{"id":"https://openalex.org/W7224733768","doi":"https://doi.org/10.1016/j.crmicr.2026.100674","title":"Interaction of outer membrane vesicles of the oral pathogen Porphyromonas gingivalis with human red blood cells disclosed by proteome analyses","display_name":"Interaction of outer membrane vesicles of the oral pathogen Porphyromonas gingivalis with human red blood cells disclosed by proteome analyses","publication_year":2026,"publication_date":"2026-10-30","ids":{"openalex":"https://openalex.org/W7224733768","doi":"https://doi.org/10.1016/j.crmicr.2026.100674"},"language":"en","primary_location":{"id":"doi:10.1016/j.crmicr.2026.100674","doi":"https://doi.org/10.1016/j.crmicr.2026.100674","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.crmicr.2026.100674","pdf_url":null,"source":{"id":"https://openalex.org/S4210236417","display_name":"Current Research in Microbial Sciences","issn_l":"2666-5174","issn":["2666-5174"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-d","jufo-1","norway-1","oarl","poland-20"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Current Research in Microbial Sciences","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","doaj"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://doi.org/10.1016/j.crmicr.2026.100674","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5008678453","display_name":"Marines du Teil Espina","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Marines du Teil Espina","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5061262088","display_name":"Rosario del Carmen Flores-Vallejo","orcid":"https://orcid.org/0000-0001-5986-9710","observed_orcids":["https://orcid.org/0000-0001-5986-9710"]},"institutions":[{"id":"https://openalex.org/I1334415907","display_name":"University Medical Center Groningen","ror":"https://ror.org/03cv38k47","country_code":"NL","type":"healthcare","lineage":["https://openalex.org/I1334415907"]},{"id":"https://openalex.org/I169381384","display_name":"University of Groningen","ror":"https://ror.org/012p63287","country_code":"NL","type":"education","lineage":["https://openalex.org/I169381384"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"Rosario del Carmen Flores-Vallejo","raw_affiliation_strings":["European Institute of Innovation and Technology (EIT), Healthy Ageing PhD School. Campus University Medical Center Groningen, University of Groningen, 9713 GZ, Groningen, the Netherlands","University of Groningen, Department of Medical Microbiology, University Medical Center Groningen, 9713 GZ, Groningen, the Netherlands"],"raw_orcid":"https://orcid.org/0000-0001-5986-9710","affiliations":[{"raw_affiliation_string":"European Institute of Innovation and Technology (EIT), Healthy Ageing PhD School. Campus University Medical Center Groningen, University of Groningen, 9713 GZ, Groningen, the Netherlands","institution_ids":["https://openalex.org/I1334415907","https://openalex.org/I169381384"]},{"raw_affiliation_string":"University of Groningen, Department of Medical Microbiology, University Medical Center Groningen, 9713 GZ, Groningen, the Netherlands","institution_ids":["https://openalex.org/I1334415907","https://openalex.org/I169381384"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5032102414","display_name":"Claudia Hirschfeld","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I36522303","display_name":"Universit\u00e4t Greifswald","ror":"https://ror.org/00r1edq15","country_code":"DE","type":"education","lineage":["https://openalex.org/I36522303"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Claudia Hirschfeld","raw_affiliation_strings":["University of Greifswald, Department of Microbial Physiology and Molecular Biology, Institute of Microbiology, Greifswald, 17489, Germany","University of Greifswald, Department of Microbial Proteomics, Institute of Microbiology, Greifswald, 17489, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Greifswald, Department of Microbial Physiology and Molecular Biology, Institute of Microbiology, Greifswald, 17489, Germany","institution_ids":["https://openalex.org/I36522303"]},{"raw_affiliation_string":"University of Greifswald, Department of Microbial Proteomics, Institute of Microbiology, Greifswald, 17489, Germany","institution_ids":["https://openalex.org/I36522303"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5057673320","display_name":"Stefano Grasso","orcid":"https://orcid.org/0000-0002-6958-9912","observed_orcids":["https://orcid.org/0000-0002-6958-9912"]},"institutions":[{"id":"https://openalex.org/I1334415907","display_name":"University Medical Center Groningen","ror":"https://ror.org/03cv38k47","country_code":"NL","type":"healthcare","lineage":["https://openalex.org/I1334415907"]},{"id":"https://openalex.org/I169381384","display_name":"University of Groningen","ror":"https://ror.org/012p63287","country_code":"NL","type":"education","lineage":["https://openalex.org/I169381384"]},{"id":"https://openalex.org/I4210102312","display_name":"Lesaffre (France)","ror":"https://ror.org/00r23cm16","country_code":"FR","type":"company","lineage":["https://openalex.org/I4210102312"]}],"countries":["FR","NL"],"is_corresponding":false,"raw_author_name":"Stefano Grasso","raw_affiliation_strings":["Lesaffre International, 101 Rue de Menin, Marcq-en-Bar\u0153ul 59700, Marquette-lez-Lille, France","University of Groningen, Department of Medical Microbiology, University Medical Center Groningen, 9713 GZ, Groningen, the Netherlands"],"raw_orcid":"https://orcid.org/0000-0002-6958-9912","affiliations":[{"raw_affiliation_string":"Lesaffre International, 101 Rue de Menin, Marcq-en-Bar\u0153ul 59700, Marquette-lez-Lille, France","institution_ids":["https://openalex.org/I4210102312"]},{"raw_affiliation_string":"University of Groningen, Department of Medical Microbiology, University Medical Center Groningen, 9713 GZ, Groningen, the Netherlands","institution_ids":["https://openalex.org/I1334415907","https://openalex.org/I169381384"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5044218865","display_name":"Pim Rozendal","orcid":"https://orcid.org/0000-0002-0741-2249","observed_orcids":["https://orcid.org/0000-0002-0741-2249"]},"institutions":[{"id":"https://openalex.org/I1334415907","display_name":"University Medical Center Groningen","ror":"https://ror.org/03cv38k47","country_code":"NL","type":"healthcare","lineage":["https://openalex.org/I1334415907"]},{"id":"https://openalex.org/I169381384","display_name":"University of Groningen","ror":"https://ror.org/012p63287","country_code":"NL","type":"education","lineage":["https://openalex.org/I169381384"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"Pim Rozendal","raw_affiliation_strings":["University of Groningen, Department of Medical Microbiology, University Medical Center Groningen, 9713 GZ, Groningen, the Netherlands"],"raw_orcid":"https://orcid.org/0000-0002-0741-2249","affiliations":[{"raw_affiliation_string":"University of Groningen, Department of Medical Microbiology, University Medical Center Groningen, 9713 GZ, Groningen, the Netherlands","institution_ids":["https://openalex.org/I1334415907","https://openalex.org/I169381384"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5016432606","display_name":"Anke Trautwein\u2010Schult","orcid":"https://orcid.org/0000-0003-3272-5746","observed_orcids":["https://orcid.org/0000-0003-3272-5746"]},"institutions":[{"id":"https://openalex.org/I36522303","display_name":"Universit\u00e4t Greifswald","ror":"https://ror.org/00r1edq15","country_code":"DE","type":"education","lineage":["https://openalex.org/I36522303"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Anke Trautwein-Schult","raw_affiliation_strings":["University of Greifswald, Department of Microbial Proteomics, Institute of Microbiology, Greifswald, 17489, Germany"],"raw_orcid":"https://orcid.org/0000-0003-3272-5746","affiliations":[{"raw_affiliation_string":"University of Greifswald, Department of Microbial Proteomics, Institute of Microbiology, Greifswald, 17489, Germany","institution_ids":["https://openalex.org/I36522303"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5080866705","display_name":"D\u00f6rte Becher","orcid":"https://orcid.org/0000-0002-9630-5735","observed_orcids":["https://orcid.org/0000-0002-9630-5735"]},"institutions":[{"id":"https://openalex.org/I36522303","display_name":"Universit\u00e4t Greifswald","ror":"https://ror.org/00r1edq15","country_code":"DE","type":"education","lineage":["https://openalex.org/I36522303"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"D\u00f6rte Becher","raw_affiliation_strings":["University of Greifswald, Department of Microbial Proteomics, Institute of Microbiology, Greifswald, 17489, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Greifswald, Department of Microbial Proteomics, Institute of Microbiology, Greifswald, 17489, Germany","institution_ids":["https://openalex.org/I36522303"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5071837419","display_name":"Giorgio Gabarrini","orcid":"https://orcid.org/0000-0001-6936-4919","observed_orcids":["https://orcid.org/0000-0001-6936-4919"]},"institutions":[{"id":"https://openalex.org/I1334415907","display_name":"University Medical Center Groningen","ror":"https://ror.org/03cv38k47","country_code":"NL","type":"healthcare","lineage":["https://openalex.org/I1334415907"]},{"id":"https://openalex.org/I169381384","display_name":"University of Groningen","ror":"https://ror.org/012p63287","country_code":"NL","type":"education","lineage":["https://openalex.org/I169381384"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"Giorgio Gabarrini","raw_affiliation_strings":["ImmunoIVD, Nacka Strand, Stockholm, 13152, Sweden","University of Groningen, Department of Medical Microbiology, University Medical Center Groningen, 9713 GZ, Groningen, the Netherlands"],"raw_orcid":"https://orcid.org/0000-0001-6936-4919","affiliations":[{"raw_affiliation_string":"ImmunoIVD, Nacka Strand, Stockholm, 13152, Sweden","institution_ids":[]},{"raw_affiliation_string":"University of Groningen, Department of Medical Microbiology, University Medical Center Groningen, 9713 GZ, Groningen, the Netherlands","institution_ids":["https://openalex.org/I1334415907","https://openalex.org/I169381384"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5070787254","display_name":"Jan Maarten van Dijl","orcid":"https://orcid.org/0000-0002-5688-8438","observed_orcids":["https://orcid.org/0000-0002-5688-8438"]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Jan Maarten van Dijl","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-5688-8438","affiliations":[]}],"institutions":[],"countries_distinct_count":3,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5070787254"],"corresponding_institution_ids":[],"apc_list":{"value":2680,"currency":"USD","value_usd":2680},"apc_paid":{"value":2680,"currency":"USD","value_usd":2680},"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.87344091,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"11","issue":null,"first_page":"100674","last_page":"100674"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10257","display_name":"Oral microbiology and periodontitis research","score":0.9868000149726868,"subfield":{"id":"https://openalex.org/subfields/3506","display_name":"Periodontics"},"field":{"id":"https://openalex.org/fields/35","display_name":"Dentistry"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10257","display_name":"Oral microbiology and periodontitis research","score":0.9868000149726868,"subfield":{"id":"https://openalex.org/subfields/3506","display_name":"Periodontics"},"field":{"id":"https://openalex.org/fields/35","display_name":"Dentistry"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10873","display_name":"Bacterial Infections and Vaccines","score":0.009200000204145908,"subfield":{"id":"https://openalex.org/subfields/2404","display_name":"Microbiology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10943","display_name":"Escherichia coli research studies","score":0.0005000000237487257,"subfield":{"id":"https://openalex.org/subfields/1310","display_name":"Endocrinology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/porphyromonas-gingivalis","display_name":"Porphyromonas gingivalis","score":1.0},{"id":"https://openalex.org/keywords/outer-membrane-vesicles","display_name":"outer membrane vesicles","score":1.0},{"id":"https://openalex.org/keywords/peptidylarginine-deiminase","display_name":"peptidylarginine deiminase","score":0.925000011920929},{"id":"https://openalex.org/keywords/type-ix-secretion-system","display_name":"type IX secretion system","score":0.7879999876022339},{"id":"https://openalex.org/keywords/erythrocyte-binding","display_name":"erythrocyte binding","score":0.5960000157356262},{"id":"https://openalex.org/keywords/hemagglutination","display_name":"hemagglutination","score":0.9909999966621399},{"id":"https://openalex.org/keywords/hemolysis","display_name":"hemolysis","score":0.9789999723434448},{"id":"https://openalex.org/keywords/iron-acquisition","display_name":"iron acquisition","score":0.8230000138282776},{"id":"https://openalex.org/keywords/heme-acquisition","display_name":"heme acquisition","score":1.0},{"id":"https://openalex.org/keywords/virulence-factors","display_name":"virulence factors","score":0.7730000019073486},{"id":"https://openalex.org/keywords/periodontitis","display_name":"periodontitis","score":0.9100000262260437},{"id":"https://openalex.org/keywords/bacterial-dissemination","display_name":"bacterial dissemination","score":0.4180000126361847}],"concepts":[{"id":"https://openalex.org/C2780183776","wikidata":"https://www.wikidata.org/wiki/Q3214147","display_name":"Porphyromonas gingivalis","level":3,"score":0.9139999747276306},{"id":"https://openalex.org/C146587185","wikidata":"https://www.wikidata.org/wiki/Q258248","display_name":"Bacterial outer membrane","level":4,"score":0.8837000131607056},{"id":"https://openalex.org/C104397665","wikidata":"https://www.wikidata.org/wiki/Q860947","display_name":"Proteome","level":2,"score":0.8116000294685364},{"id":"https://openalex.org/C60987743","wikidata":"https://www.wikidata.org/wiki/Q1460232","display_name":"Virulence","level":3,"score":0.7343000173568726},{"id":"https://openalex.org/C89423630","wikidata":"https://www.wikidata.org/wiki/Q7193","display_name":"Microbiology","level":1,"score":0.6978999972343445},{"id":"https://openalex.org/C201663137","wikidata":"https://www.wikidata.org/wiki/Q21198990","display_name":"Periplasmic space","level":4,"score":0.5874999761581421},{"id":"https://openalex.org/C2776460866","wikidata":"https://www.wikidata.org/wiki/Q170065","display_name":"Pathogen","level":2,"score":0.5591999888420105},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.5546000003814697},{"id":"https://openalex.org/C2779902561","wikidata":"https://www.wikidata.org/wiki/Q471706","display_name":"Hemolysis","level":2,"score":0.477400004863739},{"id":"https://openalex.org/C2780014169","wikidata":"https://www.wikidata.org/wiki/Q7168662","display_name":"Periodontal pathogen","level":4,"score":0.460099995136261},{"id":"https://openalex.org/C144647389","wikidata":"https://www.wikidata.org/wiki/Q423042","display_name":"Membrane protein","level":3,"score":0.41429999470710754},{"id":"https://openalex.org/C2780187896","wikidata":"https://www.wikidata.org/wiki/Q134745","display_name":"Treponema","level":4,"score":0.4090999960899353},{"id":"https://openalex.org/C2777327803","wikidata":"https://www.wikidata.org/wiki/Q7683667","display_name":"Tannerella forsythia","level":5,"score":0.4081000089645386},{"id":"https://openalex.org/C2776217839","wikidata":"https://www.wikidata.org/wiki/Q189621","display_name":"Heme","level":3,"score":0.40209999680519104},{"id":"https://openalex.org/C49039625","wikidata":"https://www.wikidata.org/wiki/Q84230","display_name":"Secretion","level":2,"score":0.3978999853134155},{"id":"https://openalex.org/C523546767","wikidata":"https://www.wikidata.org/wiki/Q10876","display_name":"Bacteria","level":2,"score":0.39070001244544983},{"id":"https://openalex.org/C24527192","wikidata":"https://www.wikidata.org/wiki/Q17149729","display_name":"Human pathogen","level":3,"score":0.3752000033855438},{"id":"https://openalex.org/C2778754761","wikidata":"https://www.wikidata.org/wiki/Q421804","display_name":"Lipopolysaccharide","level":2,"score":0.3361999988555908},{"id":"https://openalex.org/C2776357993","wikidata":"https://www.wikidata.org/wiki/Q4840030","display_name":"Bacteroidaceae","level":3,"score":0.3321000039577484},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.31200000643730164},{"id":"https://openalex.org/C111684460","wikidata":"https://www.wikidata.org/wiki/Q334848","display_name":"Complement system","level":3,"score":0.2921000123023987},{"id":"https://openalex.org/C2776051709","wikidata":"https://www.wikidata.org/wiki/Q632006","display_name":"Gram-negative bacteria","level":4,"score":0.2777999937534332},{"id":"https://openalex.org/C24530287","wikidata":"https://www.wikidata.org/wiki/Q424204","display_name":"Transmembrane protein","level":3,"score":0.2775000035762787},{"id":"https://openalex.org/C62130838","wikidata":"https://www.wikidata.org/wiki/Q5196163","display_name":"Pathogenicity island","level":4,"score":0.2712000012397766},{"id":"https://openalex.org/C130316041","wikidata":"https://www.wikidata.org/wiki/Q189206","display_name":"Vesicle","level":3,"score":0.27070000767707825},{"id":"https://openalex.org/C71318922","wikidata":"https://www.wikidata.org/wiki/Q426181","display_name":"Complement component 5","level":4,"score":0.26269999146461487},{"id":"https://openalex.org/C2781090273","wikidata":"https://www.wikidata.org/wiki/Q1623405","display_name":"Virulence factor","level":4,"score":0.2535000145435333}],"mesh":[],"locations_count":2,"locations":[{"id":"doi:10.1016/j.crmicr.2026.100674","doi":"https://doi.org/10.1016/j.crmicr.2026.100674","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.crmicr.2026.100674","pdf_url":null,"source":{"id":"https://openalex.org/S4210236417","display_name":"Current Research in Microbial Sciences","issn_l":"2666-5174","issn":["2666-5174"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-d","jufo-1","norway-1","oarl","poland-20"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Current Research in Microbial Sciences","raw_type":"journal-article"},{"id":"pmh:oai:doaj.org/article:8ca4ff51eda5406cbcbf150d195ea679","doi":null,"is_oa":false,"landing_page_url":"https://doaj.org/article/8ca4ff51eda5406cbcbf150d195ea679","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Current Research in Microbial Sciences, Vol 11, Iss , Pp 100674- (2026)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.1016/j.crmicr.2026.100674","doi":"https://doi.org/10.1016/j.crmicr.2026.100674","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.crmicr.2026.100674","pdf_url":null,"source":{"id":"https://openalex.org/S4210236417","display_name":"Current Research in Microbial Sciences","issn_l":"2666-5174","issn":["2666-5174"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-d","jufo-1","norway-1","oarl","poland-20"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Current Research in Microbial Sciences","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.9391000270843506}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320321739","display_name":"Consejo Nacional de Ciencia y Tecnolog\u00eda","ror":"https://ror.org/059ex5q34"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":115,"referenced_works":["https://openalex.org/W1560020441","https://openalex.org/W1691524838","https://openalex.org/W1821691195","https://openalex.org/W1825352697","https://openalex.org/W1836157892","https://openalex.org/W1900937478","https://openalex.org/W1917110699","https://openalex.org/W1964516944","https://openalex.org/W1973519236","https://openalex.org/W1979151099","https://openalex.org/W1990025846","https://openalex.org/W1991825361","https://openalex.org/W1998890104","https://openalex.org/W2007267559","https://openalex.org/W2010759599","https://openalex.org/W2021545698","https://openalex.org/W2028854133","https://openalex.org/W2036321220","https://openalex.org/W2043248182","https://openalex.org/W2045015942","https://openalex.org/W2056077453","https://openalex.org/W2071624135","https://openalex.org/W2071899271","https://openalex.org/W2075963746","https://openalex.org/W2080752012","https://openalex.org/W2082507075","https://openalex.org/W2084115323","https://openalex.org/W2086953830","https://openalex.org/W2095691138","https://openalex.org/W2098619370","https://openalex.org/W2101291993","https://openalex.org/W2103991421","https://openalex.org/W2114737779","https://openalex.org/W2123764746","https://openalex.org/W2126470914","https://openalex.org/W2127322768","https://openalex.org/W2127683899","https://openalex.org/W2135807668","https://openalex.org/W2141198567","https://openalex.org/W2142678478","https://openalex.org/W2142695127","https://openalex.org/W2145502538","https://openalex.org/W2146766390","https://openalex.org/W2156618766","https://openalex.org/W2167131572","https://openalex.org/W2170776626","https://openalex.org/W2171858045","https://openalex.org/W2178452720","https://openalex.org/W2192030661","https://openalex.org/W2315766670","https://openalex.org/W2316646952","https://openalex.org/W2317868549","https://openalex.org/W2346283343","https://openalex.org/W2404222461","https://openalex.org/W2463195069","https://openalex.org/W2528528379","https://openalex.org/W2529479209","https://openalex.org/W2554624417","https://openalex.org/W2619363404","https://openalex.org/W2736180350","https://openalex.org/W2748973404","https://openalex.org/W2782533799","https://openalex.org/W2787617893","https://openalex.org/W2793788871","https://openalex.org/W2796138116","https://openalex.org/W2797879107","https://openalex.org/W2805001896","https://openalex.org/W2806734624","https://openalex.org/W2891887939","https://openalex.org/W2899299976","https://openalex.org/W2912555658","https://openalex.org/W2913159336","https://openalex.org/W2913584714","https://openalex.org/W2914092103","https://openalex.org/W2972603299","https://openalex.org/W2976719148","https://openalex.org/W2988396470","https://openalex.org/W2990075650","https://openalex.org/W2997646075","https://openalex.org/W2999712948","https://openalex.org/W3004817752","https://openalex.org/W3006516341","https://openalex.org/W3034202342","https://openalex.org/W3040530029","https://openalex.org/W3046406930","https://openalex.org/W3094967361","https://openalex.org/W3096855089","https://openalex.org/W3097636277","https://openalex.org/W3109085939","https://openalex.org/W3112376646","https://openalex.org/W3198361296","https://openalex.org/W4205861010","https://openalex.org/W4220973836","https://openalex.org/W4282542855","https://openalex.org/W4286697422","https://openalex.org/W4290730903","https://openalex.org/W4293214573","https://openalex.org/W4293230947","https://openalex.org/W4306918395","https://openalex.org/W4312046006","https://openalex.org/W4313489034","https://openalex.org/W4319461542","https://openalex.org/W4383187200","https://openalex.org/W4391471488","https://openalex.org/W4400930802","https://openalex.org/W4405869758","https://openalex.org/W4406657204","https://openalex.org/W4406739472","https://openalex.org/W4407351216","https://openalex.org/W4410217681","https://openalex.org/W4411026247","https://openalex.org/W7131786715","https://openalex.org/W7132852386","https://openalex.org/W7154038326","https://openalex.org/W7161628705"],"related_works":["https://openalex.org/W2316646952","https://openalex.org/W2805001896","https://openalex.org/W3097636277","https://openalex.org/W2127683899","https://openalex.org/W2061809527","https://openalex.org/W4387581263","https://openalex.org/W4409072204","https://openalex.org/W2103614811","https://openalex.org/W2090671384","https://openalex.org/W4399466631"],"abstract_inverted_index":{"Porphyromonas":[0],"gingivalis":[1,38,76,192,218],"is":[2],"a":[3,238],"keystone":[4],"oral":[5],"pathogen":[6],"implicated":[7],"in":[8,178],"periodontitis":[9],"and":[10,49,80,88,91,108,180,200,226,229],"several":[11],"other":[12],"pro-inflammatory":[13],"or":[14],"degenerative":[15],"diseases.":[16],"Previous":[17],"studies":[18],"showed":[19],"that":[20,190,232],"outer":[21,109],"membrane":[22],"vesicles":[23],"(OMVs)":[24],"produced":[25],"by":[26,159],"this":[27],"Gram-negative":[28],"bacterium":[29],"are":[30,194],"loaded":[31],"with":[32,220],"virulence":[33,140],"factors,":[34,141],"including":[35,78,143],"the":[36,50,63,84,105,131,148,155,165,170,187,245],"P.":[37,75,191,217],"peptidyl-arginine":[39],"deiminase":[40],"(PPAD).":[41],"However,":[42],"our":[43,210],"understanding":[44],"of":[45,52,72,83,139,147,198,205,216],"strain-specific":[46],"OMV":[47,55,70,112,125,156,242],"features":[48],"impact":[51],"PPAD":[53],"on":[54],"cargo":[56,126],"composition":[57],"was":[58,66],"so":[59],"far":[60],"limited.":[61],"Therefore,":[62],"present":[64,211],"study":[65],"aimed":[67],"at":[68],"comparing":[69],"proteomes":[71],"six":[73],"different":[74],"strains,":[77],"PPAD-proficient":[79,167],"-deficient":[81],"variants":[82],"type":[85,132],"strains":[86],"W83":[87],"ATCC":[89],"33277,":[90],"two":[92],"clinical":[93],"isolates.":[94],"Per":[95],"strain,":[96],"100\u2013203":[97],"OMV-borne":[98],"proteins":[99,127,176],"were":[100,128],"identified,":[101],"originating":[102],"mostly":[103],"from":[104,164],"bacterial":[106],"periplasm":[107],"membrane.":[110],"The":[111],"core":[113],"proteome":[114,212],"included":[115],"79":[116],"orthogroups":[117],"representing":[118],"11":[119],"biological":[120],"pathways.":[121],"Interestingly,":[122],"23":[123],"identified":[124],"related":[129,223],"to":[130,162,201,224,234],"IX":[133],"secretion":[134],"system":[135],"(T9SS)":[136],"for":[137,186,241],"export":[138],"invariably":[142,173],"all":[144],"four":[145],"components":[146],"so-called":[149],"T9SS":[150],"attachment":[151,233],"complex.":[152],"PPAD-deficiency":[153],"altered":[154],"protein":[157],"content":[158],"\u223c18%":[160],"compared":[161],"OMVs":[163,172,193,219],"respective":[166],"strains.":[168],"Lastly,":[169],"investigated":[171],"carried":[174],"multiple":[175],"involved":[177],"iron":[179,227],"heme":[181,225],"acquisition.":[182],"Accordingly,":[183],"we":[184],"demonstrate":[185],"first":[188],"time":[189],"highly":[195],"potent":[196],"inducers":[197],"hemagglutination":[199],"lesser":[202],"extent":[203],"hemolysis":[204],"human":[206,221,246],"erythrocytes.":[207],"In":[208],"conclusion,":[209],"analyses":[213],"disclose":[214],"interactions":[215],"erythrocytes":[222,235],"acquisition,":[228],"they":[230],"suggest":[231],"could":[236],"represent":[237],"plausible":[239],"mechanism":[240],"dissemination":[243],"throughout":[244],"body.":[247]},"counts_by_year":[],"updated_date":"2026-11-03T10:50:19.383937","created_date":"2026-10-31T00:00:00"}