{"id":"https://openalex.org/W7224466542","doi":"https://doi.org/10.1007/s00580-026-03876-x","title":"Systemic granulomatous disease of unknown origin in cattle: epidemiologic investigation of a clustered outbreak","display_name":"Systemic granulomatous disease of unknown origin in cattle: epidemiologic investigation of a clustered outbreak","publication_year":2026,"publication_date":"2026-10-29","ids":{"openalex":"https://openalex.org/W7224466542","doi":"https://doi.org/10.1007/s00580-026-03876-x"},"language":"en","primary_location":{"id":"doi:10.1007/s00580-026-03876-x","doi":"https://doi.org/10.1007/s00580-026-03876-x","is_oa":true,"landing_page_url":"https://doi.org/10.1007/s00580-026-03876-x","pdf_url":"https://link.springer.com/content/pdf/10.1007/s00580-026-03876-x.pdf","source":{"id":"https://openalex.org/S4210222653","display_name":"Comparative Clinical Pathology","issn_l":"0938-7714","issn":["0938-7714","1433-2973","1618-5641","1618-565X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","jufo-1","norway-1","poland-40","russia-white-list-2"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Comparative Clinical Pathology","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://link.springer.com/content/pdf/10.1007/s00580-026-03876-x.pdf","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5045131615","display_name":"Ricardo E. Mendes","orcid":"https://orcid.org/0000-0001-9222-3479","observed_orcids":["https://orcid.org/0000-0001-9222-3479"]},"institutions":[{"id":"https://openalex.org/I165733156","display_name":"University of Georgia","ror":"https://ror.org/00te3t702","country_code":"US","type":"education","lineage":["https://openalex.org/I165733156"]},{"id":"https://openalex.org/I4210118451","display_name":"Instituto Federal Catarinense","ror":"https://ror.org/02f8h1m78","country_code":"BR","type":"facility","lineage":["https://openalex.org/I4210118451"]}],"countries":["BR","US"],"is_corresponding":true,"raw_author_name":"Ricardo E. Mendes","raw_affiliation_strings":["Athens Veterinary Diagnostic Laboratory (AVDL), Department of Pathology, College of Veterinary Medicine, University of Georgia (UGA), Athens, USA","Laborat\u00f3rio de Patologia Veterin\u00e1ria (LPV), Instituto Federal Catarinense (IFC), Conc\u00f3rdia, Brazil"],"raw_orcid":"https://orcid.org/0000-0001-9222-3479","affiliations":[{"raw_affiliation_string":"Athens Veterinary Diagnostic Laboratory (AVDL), Department of Pathology, College of Veterinary Medicine, University of Georgia (UGA), Athens, USA","institution_ids":["https://openalex.org/I165733156"]},{"raw_affiliation_string":"Laborat\u00f3rio de Patologia Veterin\u00e1ria (LPV), Instituto Federal Catarinense (IFC), Conc\u00f3rdia, Brazil","institution_ids":["https://openalex.org/I4210118451"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5031459083","display_name":"Ana Fl\u00e1via Begnini","orcid":"https://orcid.org/0000-0001-7555-636X","observed_orcids":["https://orcid.org/0000-0001-7555-636X"]},"institutions":[{"id":"https://openalex.org/I4210118451","display_name":"Instituto Federal Catarinense","ror":"https://ror.org/02f8h1m78","country_code":"BR","type":"facility","lineage":["https://openalex.org/I4210118451"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Ana F. Begnini","raw_affiliation_strings":["Laborat\u00f3rio de Patologia Veterin\u00e1ria (LPV), Instituto Federal Catarinense (IFC), Conc\u00f3rdia, Brazil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laborat\u00f3rio de Patologia Veterin\u00e1ria (LPV), Instituto Federal Catarinense (IFC), Conc\u00f3rdia, Brazil","institution_ids":["https://openalex.org/I4210118451"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5091058526","display_name":"Giovana Pelisser","orcid":"https://orcid.org/0000-0003-4821-8247","observed_orcids":["https://orcid.org/0000-0003-4821-8247","https://orcid.org/0000-0001-5641-5756"]},"institutions":[{"id":"https://openalex.org/I4210118451","display_name":"Instituto Federal Catarinense","ror":"https://ror.org/02f8h1m78","country_code":"BR","type":"facility","lineage":["https://openalex.org/I4210118451"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Giovana Pelisser","raw_affiliation_strings":["Laborat\u00f3rio de Patologia Veterin\u00e1ria (LPV), Instituto Federal Catarinense (IFC), Conc\u00f3rdia, Brazil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laborat\u00f3rio de Patologia Veterin\u00e1ria (LPV), Instituto Federal Catarinense (IFC), Conc\u00f3rdia, Brazil","institution_ids":["https://openalex.org/I4210118451"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5043723123","display_name":"Vitor Waldir Horn","orcid":"https://orcid.org/0000-0001-8057-5717","observed_orcids":["https://orcid.org/0000-0001-8057-5717"]},"institutions":[{"id":"https://openalex.org/I4210118451","display_name":"Instituto Federal Catarinense","ror":"https://ror.org/02f8h1m78","country_code":"BR","type":"facility","lineage":["https://openalex.org/I4210118451"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Vitor W. Horn","raw_affiliation_strings":["Laborat\u00f3rio de Patologia Veterin\u00e1ria (LPV), Instituto Federal Catarinense (IFC), Conc\u00f3rdia, Brazil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laborat\u00f3rio de Patologia Veterin\u00e1ria (LPV), Instituto Federal Catarinense (IFC), Conc\u00f3rdia, Brazil","institution_ids":["https://openalex.org/I4210118451"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5093692866","display_name":"Raphael Adenir Valeriano Tonin","orcid":"https://orcid.org/0009-0002-6621-6392","observed_orcids":["https://orcid.org/0009-0002-6621-6392"]},"institutions":[{"id":"https://openalex.org/I4210118451","display_name":"Instituto Federal Catarinense","ror":"https://ror.org/02f8h1m78","country_code":"BR","type":"facility","lineage":["https://openalex.org/I4210118451"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Raphael V. A. Tonin","raw_affiliation_strings":["Laborat\u00f3rio de Patologia Veterin\u00e1ria (LPV), Instituto Federal Catarinense (IFC), Conc\u00f3rdia, Brazil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laborat\u00f3rio de Patologia Veterin\u00e1ria (LPV), Instituto Federal Catarinense (IFC), Conc\u00f3rdia, Brazil","institution_ids":["https://openalex.org/I4210118451"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5017725605","display_name":"Caroline Auer","orcid":"https://orcid.org/0000-0003-4385-8624","observed_orcids":["https://orcid.org/0000-0003-4385-8624"]},"institutions":[{"id":"https://openalex.org/I4210118451","display_name":"Instituto Federal Catarinense","ror":"https://ror.org/02f8h1m78","country_code":"BR","type":"facility","lineage":["https://openalex.org/I4210118451"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Caroline Auer","raw_affiliation_strings":["Laborat\u00f3rio de Patologia Veterin\u00e1ria (LPV), Instituto Federal Catarinense (IFC), Conc\u00f3rdia, Brazil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laborat\u00f3rio de Patologia Veterin\u00e1ria (LPV), Instituto Federal Catarinense (IFC), Conc\u00f3rdia, Brazil","institution_ids":["https://openalex.org/I4210118451"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5093692867","display_name":"\u00c9rica Boldori","orcid":"https://orcid.org/0009-0003-0279-1600","observed_orcids":["https://orcid.org/0009-0003-0279-1600"]},"institutions":[{"id":"https://openalex.org/I4210118451","display_name":"Instituto Federal Catarinense","ror":"https://ror.org/02f8h1m78","country_code":"BR","type":"facility","lineage":["https://openalex.org/I4210118451"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"\u00c9rica Boldori","raw_affiliation_strings":["Laborat\u00f3rio de Patologia Veterin\u00e1ria (LPV), Instituto Federal Catarinense (IFC), Conc\u00f3rdia, Brazil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laborat\u00f3rio de Patologia Veterin\u00e1ria (LPV), Instituto Federal Catarinense (IFC), Conc\u00f3rdia, Brazil","institution_ids":["https://openalex.org/I4210118451"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5093694479","display_name":"Guilherme Lima Landim","orcid":"https://orcid.org/0009-0008-9577-2084","observed_orcids":["https://orcid.org/0009-0008-9577-2084"]},"institutions":[{"id":"https://openalex.org/I165733156","display_name":"University of Georgia","ror":"https://ror.org/00te3t702","country_code":"US","type":"education","lineage":["https://openalex.org/I165733156"]},{"id":"https://openalex.org/I4210118451","display_name":"Instituto Federal Catarinense","ror":"https://ror.org/02f8h1m78","country_code":"BR","type":"facility","lineage":["https://openalex.org/I4210118451"]}],"countries":["BR","US"],"is_corresponding":false,"raw_author_name":"Guilherme L. Landim","raw_affiliation_strings":["Athens Veterinary Diagnostic Laboratory (AVDL), Department of Pathology, College of Veterinary Medicine, University of Georgia (UGA), Athens, USA","Laborat\u00f3rio de Patologia Veterin\u00e1ria (LPV), Instituto Federal Catarinense (IFC), Conc\u00f3rdia, Brazil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Athens Veterinary Diagnostic Laboratory (AVDL), Department of Pathology, College of Veterinary Medicine, University of Georgia (UGA), Athens, USA","institution_ids":["https://openalex.org/I165733156"]},{"raw_affiliation_string":"Laborat\u00f3rio de Patologia Veterin\u00e1ria (LPV), Instituto Federal Catarinense (IFC), Conc\u00f3rdia, Brazil","institution_ids":["https://openalex.org/I4210118451"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5056483646","display_name":"Rudi Weiblen","orcid":"https://orcid.org/0000-0002-1737-9817","observed_orcids":["https://orcid.org/0000-0002-1737-9817"]},"institutions":[{"id":"https://openalex.org/I33501960","display_name":"Universidade Federal de Santa Maria","ror":"https://ror.org/01b78mz79","country_code":"BR","type":"education","lineage":["https://openalex.org/I33501960"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Rudi Weiblen","raw_affiliation_strings":["Setor de Virologia, Departamento de Medicina Veterin\u00e1ria Preventiva, Universidade Federal de Santa Maria (UFSM), Santa Maria, Brazil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Setor de Virologia, Departamento de Medicina Veterin\u00e1ria Preventiva, Universidade Federal de Santa Maria (UFSM), Santa Maria, Brazil","institution_ids":["https://openalex.org/I33501960"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5061762838","display_name":"Daniel R. Rissi","orcid":"https://orcid.org/0000-0003-4574-2836","observed_orcids":["https://orcid.org/0000-0003-4574-2836"]},"institutions":[{"id":"https://openalex.org/I165733156","display_name":"University of Georgia","ror":"https://ror.org/00te3t702","country_code":"US","type":"education","lineage":["https://openalex.org/I165733156"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Daniel R. Rissi","raw_affiliation_strings":["Athens Veterinary Diagnostic Laboratory (AVDL), Department of Pathology, College of Veterinary Medicine, University of Georgia (UGA), Athens, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Athens Veterinary Diagnostic Laboratory (AVDL), Department of Pathology, College of Veterinary Medicine, University of Georgia (UGA), Athens, USA","institution_ids":["https://openalex.org/I165733156"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5045131615"],"corresponding_institution_ids":["https://openalex.org/I165733156","https://openalex.org/I4210118451"],"apc_list":{"value":3690,"currency":"USD","value_usd":3690},"apc_paid":{"value":3690,"currency":"USD","value_usd":3690},"fwci":0.0,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":{"value":0.8812181,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"35","issue":"1","first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11580","display_name":"Veterinary Medicine and Surgery","score":0.3521000146865845,"subfield":{"id":"https://openalex.org/subfields/3404","display_name":"Small Animals"},"field":{"id":"https://openalex.org/fields/34","display_name":"Veterinary"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11580","display_name":"Veterinary Medicine and Surgery","score":0.3521000146865845,"subfield":{"id":"https://openalex.org/subfields/3404","display_name":"Small Animals"},"field":{"id":"https://openalex.org/fields/34","display_name":"Veterinary"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12756","display_name":"Plant Toxicity and Pharmacological Properties","score":0.1525000035762787,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12944","display_name":"Animal Nutrition and Health","score":0.11029999703168869,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/systemic-granulomatous-disease","display_name":"systemic granulomatous disease","score":0.9359999895095825},{"id":"https://openalex.org/keywords/cattle","display_name":"cattle","score":0.9430000185966492},{"id":"https://openalex.org/keywords/dairy-cows","display_name":"dairy cattle","score":0.574999988079071},{"id":"https://openalex.org/keywords/beef-cattle","display_name":"beef cattle","score":0.996999979019165},{"id":"https://openalex.org/keywords/mineral-premix","display_name":"mineral premix","score":0.7549999952316284},{"id":"https://openalex.org/keywords/feed-additives","display_name":"feed additives","score":0.8629999756813049},{"id":"https://openalex.org/keywords/dicyandiamide","display_name":"dicyandiamide","score":0.8379999995231628},{"id":"https://openalex.org/keywords/granulomatous-inflammation","display_name":"granulomatous inflammation","score":0.8140000104904175}],"concepts":[{"id":"https://openalex.org/C116675565","wikidata":"https://www.wikidata.org/wiki/Q3241045","display_name":"Outbreak","level":2,"score":0.8065999746322632},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.6592000126838684},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.5152999758720398},{"id":"https://openalex.org/C107130276","wikidata":"https://www.wikidata.org/wiki/Q133805","display_name":"Epidemiology","level":2,"score":0.46700000762939453},{"id":"https://openalex.org/C2908982167","wikidata":"https://www.wikidata.org/wiki/Q830","display_name":"Cattle Diseases","level":2,"score":0.4453999996185303},{"id":"https://openalex.org/C42972112","wikidata":"https://www.wikidata.org/wiki/Q170201","display_name":"Veterinary medicine","level":1,"score":0.40130001306533813},{"id":"https://openalex.org/C2776977481","wikidata":"https://www.wikidata.org/wiki/Q2915","display_name":"Dairy cattle","level":2,"score":0.39340001344680786},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.3887999951839447},{"id":"https://openalex.org/C2778674544","wikidata":"https://www.wikidata.org/wiki/Q1414805","display_name":"Systemic disease","level":3,"score":0.36090001463890076},{"id":"https://openalex.org/C16005928","wikidata":"https://www.wikidata.org/wiki/Q171171","display_name":"Dermatology","level":1,"score":0.3239000141620636},{"id":"https://openalex.org/C3018113122","wikidata":"https://www.wikidata.org/wiki/Q1129338","display_name":"Granulomatous disease","level":3,"score":0.31369999051094055},{"id":"https://openalex.org/C2781069245","wikidata":"https://www.wikidata.org/wiki/Q12204","display_name":"Tuberculosis","level":2,"score":0.313400000333786},{"id":"https://openalex.org/C2780505807","wikidata":"https://www.wikidata.org/wiki/Q1208989","display_name":"Beef cattle","level":2,"score":0.3037000000476837},{"id":"https://openalex.org/C2775992197","wikidata":"https://www.wikidata.org/wiki/Q513631","display_name":"Raw milk","level":2,"score":0.2849999964237213},{"id":"https://openalex.org/C2779609043","wikidata":"https://www.wikidata.org/wiki/Q5441216","display_name":"Feeder cattle","level":2,"score":0.2800999879837036},{"id":"https://openalex.org/C112964050","wikidata":"https://www.wikidata.org/wiki/Q103459","display_name":"Livestock","level":2,"score":0.2793000042438507},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.2736999988555908},{"id":"https://openalex.org/C50440223","wikidata":"https://www.wikidata.org/wiki/Q1475848","display_name":"Risk factor","level":2,"score":0.27160000801086426},{"id":"https://openalex.org/C61511704","wikidata":"https://www.wikidata.org/wiki/Q1671857","display_name":"Incidence (geometry)","level":2,"score":0.2685999870300293},{"id":"https://openalex.org/C2779984200","wikidata":"https://www.wikidata.org/wiki/Q1724379","display_name":"Shorthorn","level":3,"score":0.26109999418258667},{"id":"https://openalex.org/C2776178081","wikidata":"https://www.wikidata.org/wiki/Q3286546","display_name":"Respiratory disease","level":3,"score":0.2583000063896179}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1007/s00580-026-03876-x","doi":"https://doi.org/10.1007/s00580-026-03876-x","is_oa":true,"landing_page_url":"https://doi.org/10.1007/s00580-026-03876-x","pdf_url":"https://link.springer.com/content/pdf/10.1007/s00580-026-03876-x.pdf","source":{"id":"https://openalex.org/S4210222653","display_name":"Comparative Clinical Pathology","issn_l":"0938-7714","issn":["0938-7714","1433-2973","1618-5641","1618-565X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","jufo-1","norway-1","poland-40","russia-white-list-2"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Comparative Clinical Pathology","raw_type":"journal-article"}],"best_oa_location":{"id":"doi:10.1007/s00580-026-03876-x","doi":"https://doi.org/10.1007/s00580-026-03876-x","is_oa":true,"landing_page_url":"https://doi.org/10.1007/s00580-026-03876-x","pdf_url":"https://link.springer.com/content/pdf/10.1007/s00580-026-03876-x.pdf","source":{"id":"https://openalex.org/S4210222653","display_name":"Comparative Clinical Pathology","issn_l":"0938-7714","issn":["0938-7714","1433-2973","1618-5641","1618-565X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","jufo-1","norway-1","poland-40","russia-white-list-2"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Comparative Clinical Pathology","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.6875,"id":"https://metadata.un.org/sdg/2","display_name":"Zero hunger"},{"score":0.5683000087738037,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G288602667","display_name":null,"funder_award_id":"307086/2022-4","funder_id":"https://openalex.org/F4320322025","funder_display_name":"Conselho Nacional de Desenvolvimento Cient\u00edfico e Tecnol\u00f3gico"}],"funders":[{"id":"https://openalex.org/F4320322025","display_name":"Conselho Nacional de Desenvolvimento Cient\u00edfico e Tecnol\u00f3gico","ror":"https://ror.org/03swz6y49"},{"id":"https://openalex.org/F4320330599","display_name":"Instituto Federal Catarinense","ror":"https://ror.org/00fcpmw49"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W7224466542.pdf","grobid_xml":"https://content.openalex.org/works/W7224466542.grobid-xml"},"referenced_works_count":20,"referenced_works":["https://openalex.org/W1997333350","https://openalex.org/W2002554740","https://openalex.org/W2005247207","https://openalex.org/W2011662216","https://openalex.org/W2018130679","https://openalex.org/W2052431484","https://openalex.org/W2060392556","https://openalex.org/W2081006696","https://openalex.org/W2086439020","https://openalex.org/W2111244579","https://openalex.org/W2137491277","https://openalex.org/W2145338559","https://openalex.org/W2584216064","https://openalex.org/W2775026413","https://openalex.org/W2913091190","https://openalex.org/W2932174958","https://openalex.org/W3040930767","https://openalex.org/W3120460832","https://openalex.org/W3184118068","https://openalex.org/W4401919319"],"related_works":["https://openalex.org/W2932174958","https://openalex.org/W7043726635","https://openalex.org/W7120516063","https://openalex.org/W2167018685","https://openalex.org/W78921803","https://openalex.org/W7098211909","https://openalex.org/W2081006696","https://openalex.org/W2052431484","https://openalex.org/W2802195795","https://openalex.org/W7027944768"],"abstract_inverted_index":{"Abstract":[0],"Systemic":[1],"granulomatous":[2,40,141],"disease":[3,41],"in":[4,19,45,50,72,83,115],"cattle":[5,49,54,82,137],"is":[6],"most":[7],"commonly":[8],"associated":[9],"with":[10],"hypersensitivity":[11],"to":[12],"ingested":[13],"Vicia":[14,125],"villosa":[15],".":[16],"Cases":[17],"occurring":[18],"the":[20,91,98,147,153],"absence":[21],"of":[22,38,42,90,164],"recognized":[23],"dietary":[24],"causes":[25],"or":[26],"feed":[27,165],"additives":[28],"have":[29],"rarely":[30],"been":[31],"reported.":[32],"Here":[33],"we":[34],"describe":[35],"an":[36],"outbreak":[37],"systemic":[39,140],"unknown":[43],"cause":[44],"dairy":[46,73,116],"and":[47,58,64,77,107,131,168],"beef":[48,78],"southern":[51],"Brazil.":[52],"Affected":[53],"underwent":[55],"autopsy,":[56],"histopathology,":[57],"epidemiologic":[59,154],"assessment.":[60],"Between":[61],"November":[62],"2021":[63],"January":[65],"2022,":[66,109],"14":[67],"cases":[68,87,112],"were":[69,113,133,146],"diagnosed,":[70],"both":[71],"(12":[74],"cases,":[75,80],"86%)":[76],"(2":[79],"14%)":[81],"several":[84],"farms.":[85],"These":[86],"represented":[88],"36.8%":[89],"diagnoses":[92],"issued":[93],"by":[94],"our":[95],"laboratory":[96],"during":[97,152],"same":[99],"period.":[100],"A":[101],"few":[102],"months":[103],"later,":[104],"between":[105],"April":[106],"June":[108],"five":[110],"additional":[111],"diagnosed":[114],"cattle.":[117],"Known":[118],"causative":[119],"agents,":[120],"such":[121],"as":[122],"citric":[123],"pulp,":[124],"sp.,":[126],"citrinine,":[127],"dicyandiamide,":[128],"formalin-based":[129],"additives,":[130],"viruses":[132],"ruled":[134],"out.":[135],"All":[136],"had":[138],"moderate-to-severe":[139],"inflammation.":[142],"Commercial":[143],"mineral":[144],"premixes":[145],"only":[148],"common":[149],"exposure":[150],"identified":[151],"investigation;":[155],"however,":[156],"causation":[157],"could":[158],"not":[159,172],"be":[160],"established.":[161],"Detailed":[162],"investigation":[163],"ingredients,":[166],"suppliers,":[167],"formulation":[169],"changes":[170],"was":[171],"possible.":[173]},"counts_by_year":[],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2026-10-30T00:00:00"}