{"id":"https://openalex.org/W7224366277","doi":"https://doi.org/10.1021/acssensors.6c03535","title":"Interface-Engineered Biodegradable Nanofibrous Patch Integrating Electromechanical Sensing and Wound Healing","display_name":"Interface-Engineered Biodegradable Nanofibrous Patch Integrating Electromechanical Sensing and Wound Healing","publication_year":2026,"publication_date":"2026-10-29","ids":{"openalex":"https://openalex.org/W7224366277","doi":"https://doi.org/10.1021/acssensors.6c03535","pmid":"https://pubmed.ncbi.nlm.nih.gov/42953924"},"language":"en","primary_location":{"id":"doi:10.1021/acssensors.6c03535","doi":"https://doi.org/10.1021/acssensors.6c03535","is_oa":false,"landing_page_url":"https://doi.org/10.1021/acssensors.6c03535","pdf_url":null,"source":{"id":"https://openalex.org/S2764631046","display_name":"ACS Sensors","issn_l":"2379-3694","issn":["2379-3694"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","jufo-2","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320006","host_organization_name":"American Chemical Society","host_organization_lineage":["https://openalex.org/P4310320006"],"host_organization_lineage_names":["American Chemical Society"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"ACS Sensors","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5160116104","display_name":"Lingjie Xu","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I159948400","display_name":"Jinan University","ror":"https://ror.org/02xe5ns62","country_code":"CN","type":"education","lineage":["https://openalex.org/I159948400"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Lingjie Xu","raw_affiliation_strings":["Jinan University , , ,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Jinan University , , ,","institution_ids":["https://openalex.org/I159948400"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5053292822","display_name":"Zhuangzhuang Cai","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I159948400","display_name":"Jinan University","ror":"https://ror.org/02xe5ns62","country_code":"CN","type":"education","lineage":["https://openalex.org/I159948400"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Zhuangzhuang Cai","raw_affiliation_strings":["Jinan University , , ,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Jinan University , , ,","institution_ids":["https://openalex.org/I159948400"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5122223843","display_name":"Shihao Dong","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I159948400","display_name":"Jinan University","ror":"https://ror.org/02xe5ns62","country_code":"CN","type":"education","lineage":["https://openalex.org/I159948400"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Shihao Dong","raw_affiliation_strings":["Jinan University , , ,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Jinan University , , ,","institution_ids":["https://openalex.org/I159948400"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5159584381","display_name":"Shunqing Tang","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I159948400","display_name":"Jinan University","ror":"https://ror.org/02xe5ns62","country_code":"CN","type":"education","lineage":["https://openalex.org/I159948400"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Shunqing Tang","raw_affiliation_strings":["Jinan University , , ,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Jinan University , , ,","institution_ids":["https://openalex.org/I159948400"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5159165669","display_name":"Jing Ren","orcid":"https://orcid.org/0009-0004-4068-1231","observed_orcids":["https://orcid.org/0009-0004-4068-1231"]},"institutions":[{"id":"https://openalex.org/I24943067","display_name":"Fudan University","ror":"https://ror.org/013q1eq08","country_code":"CN","type":"education","lineage":["https://openalex.org/I24943067"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Jing Ren","raw_affiliation_strings":["Fudan University , , ,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Fudan University , , ,","institution_ids":["https://openalex.org/I24943067"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5006880773","display_name":"Hang Li","orcid":"https://orcid.org/0000-0002-5892-587X","observed_orcids":["https://orcid.org/0000-0002-5892-587X"]},"institutions":[{"id":"https://openalex.org/I159948400","display_name":"Jinan University","ror":"https://ror.org/02xe5ns62","country_code":"CN","type":"education","lineage":["https://openalex.org/I159948400"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Hang Li","raw_affiliation_strings":["Jinan University , , ,"],"raw_orcid":"https://orcid.org/0000-0002-5892-587X","affiliations":[{"raw_affiliation_string":"Jinan University , , ,","institution_ids":["https://openalex.org/I159948400"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5010488547","display_name":"Xiaoying Wang","orcid":"https://orcid.org/0000-0002-3840-5543","observed_orcids":["https://orcid.org/0000-0002-3840-5543"]},"institutions":[{"id":"https://openalex.org/I159948400","display_name":"Jinan University","ror":"https://ror.org/02xe5ns62","country_code":"CN","type":"education","lineage":["https://openalex.org/I159948400"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Xiaoying Wang","raw_affiliation_strings":["Jinan University , , ,"],"raw_orcid":"https://orcid.org/0000-0002-3840-5543","affiliations":[{"raw_affiliation_string":"Jinan University , , ,","institution_ids":["https://openalex.org/I159948400"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5045764373","display_name":"Shengjie Ling","orcid":"https://orcid.org/0000-0003-1156-0479","observed_orcids":["https://orcid.org/0000-0003-1156-0479"]},"institutions":[{"id":"https://openalex.org/I24943067","display_name":"Fudan University","ror":"https://ror.org/013q1eq08","country_code":"CN","type":"education","lineage":["https://openalex.org/I24943067"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Shengjie Ling","raw_affiliation_strings":["Fudan University , , ,"],"raw_orcid":"https://orcid.org/0000-0003-1156-0479","affiliations":[{"raw_affiliation_string":"Fudan University , , ,","institution_ids":["https://openalex.org/I24943067"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5006880773","https://openalex.org/A5010488547","https://openalex.org/A5045764373"],"corresponding_institution_ids":["https://openalex.org/I159948400","https://openalex.org/I24943067"],"apc_list":{"value":4500,"currency":"USD","value_usd":4500},"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.70678662,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10729","display_name":"Electrospun Nanofibers in Biomedical Applications","score":0.45170000195503235,"subfield":{"id":"https://openalex.org/subfields/2502","display_name":"Biomaterials"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10729","display_name":"Electrospun Nanofibers in Biomedical Applications","score":0.45170000195503235,"subfield":{"id":"https://openalex.org/subfields/2502","display_name":"Biomaterials"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10771","display_name":"Wound Healing and Treatments","score":0.4214000105857849,"subfield":{"id":"https://openalex.org/subfields/2742","display_name":"Rehabilitation"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10338","display_name":"Advanced Sensor and Energy Harvesting Materials","score":0.093299999833107,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/temperature-sensing","display_name":"temperature sensing","score":0.9070000052452087},{"id":"https://openalex.org/keywords/antibacterial-activity","display_name":"antibacterial activity","score":0.9850000143051147},{"id":"https://openalex.org/keywords/hemostasis","display_name":"hemostasis","score":0.9959999918937683},{"id":"https://openalex.org/keywords/blood-coagulation","display_name":"coagulation","score":0.6990000009536743},{"id":"https://openalex.org/keywords/fibroblast-behavior","display_name":"fibroblast behavior","score":0.800000011920929},{"id":"https://openalex.org/keywords/cutaneous-wound-healing","display_name":"skin wound healing","score":0.6840000152587891},{"id":"https://openalex.org/keywords/stretchability","display_name":"stretchability","score":0.4560000002384186}],"concepts":[{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.6620000004768372},{"id":"https://openalex.org/C89429830","wikidata":"https://www.wikidata.org/wiki/Q735710","display_name":"Scaffold","level":2,"score":0.6344000101089478},{"id":"https://openalex.org/C136229726","wikidata":"https://www.wikidata.org/wiki/Q327092","display_name":"Biomedical engineering","level":1,"score":0.612500011920929},{"id":"https://openalex.org/C2780269544","wikidata":"https://www.wikidata.org/wiki/Q1509074","display_name":"Wound healing","level":2,"score":0.5153999924659729},{"id":"https://openalex.org/C171250308","wikidata":"https://www.wikidata.org/wiki/Q11468","display_name":"Nanotechnology","level":1,"score":0.42899999022483826},{"id":"https://openalex.org/C49892992","wikidata":"https://www.wikidata.org/wiki/Q1540285","display_name":"Tissue engineering","level":2,"score":0.4221000075340271},{"id":"https://openalex.org/C2993873987","wikidata":"https://www.wikidata.org/wiki/Q184753","display_name":"Wound closure","level":3,"score":0.39989998936653137},{"id":"https://openalex.org/C2993269979","wikidata":"https://www.wikidata.org/wiki/Q523536","display_name":"Wound dressing","level":2,"score":0.39169999957084656},{"id":"https://openalex.org/C202374169","wikidata":"https://www.wikidata.org/wiki/Q124291","display_name":"Electrical conductor","level":2,"score":0.3774999976158142},{"id":"https://openalex.org/C2780381497","wikidata":"https://www.wikidata.org/wiki/Q463418","display_name":"Fibroblast","level":3,"score":0.3700000047683716},{"id":"https://openalex.org/C2778414984","wikidata":"https://www.wikidata.org/wiki/Q865663","display_name":"Biomaterial","level":2,"score":0.3596999943256378},{"id":"https://openalex.org/C106487976","wikidata":"https://www.wikidata.org/wiki/Q685816","display_name":"Matrix (chemical analysis)","level":2,"score":0.35690000653266907},{"id":"https://openalex.org/C513720949","wikidata":"https://www.wikidata.org/wiki/Q1778729","display_name":"Carbon nanotube","level":2,"score":0.33719998598098755},{"id":"https://openalex.org/C144796933","wikidata":"https://www.wikidata.org/wiki/Q1533542","display_name":"Electrospinning","level":3,"score":0.33570000529289246},{"id":"https://openalex.org/C2779843651","wikidata":"https://www.wikidata.org/wiki/Q7390335","display_name":"SIGNAL (programming language)","level":2,"score":0.31610000133514404},{"id":"https://openalex.org/C1318750","wikidata":"https://www.wikidata.org/wiki/Q865663","display_name":"Biocompatible material","level":2,"score":0.29249998927116394},{"id":"https://openalex.org/C189165786","wikidata":"https://www.wikidata.org/wiki/Q193825","display_name":"Extracellular matrix","level":2,"score":0.2816999852657318},{"id":"https://openalex.org/C2780171871","wikidata":"https://www.wikidata.org/wiki/Q6804676","display_name":"Mechanobiology","level":2,"score":0.27950000762939453},{"id":"https://openalex.org/C18762648","wikidata":"https://www.wikidata.org/wiki/Q42213","display_name":"Work (physics)","level":2,"score":0.2687000036239624}],"mesh":[],"locations_count":2,"locations":[{"id":"doi:10.1021/acssensors.6c03535","doi":"https://doi.org/10.1021/acssensors.6c03535","is_oa":false,"landing_page_url":"https://doi.org/10.1021/acssensors.6c03535","pdf_url":null,"source":{"id":"https://openalex.org/S2764631046","display_name":"ACS Sensors","issn_l":"2379-3694","issn":["2379-3694"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","jufo-2","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320006","host_organization_name":"American Chemical Society","host_organization_lineage":["https://openalex.org/P4310320006"],"host_organization_lineage_names":["American Chemical Society"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"ACS Sensors","raw_type":"journal-article"},{"id":"pmid:42953924","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/42953924","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"ACS sensors","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.4043000042438507,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320321001","display_name":"National Natural Science Foundation of China","ror":"https://ror.org/01h0zpd94"},{"id":"https://openalex.org/F4320322292","display_name":"Jinan University","ror":"https://ror.org/02xe5ns62"},{"id":"https://openalex.org/F4320335956","display_name":"Key Technologies Research and Development Program of Guangzhou","ror":null},{"id":"https://openalex.org/F4320337111","display_name":"Basic and Applied Basic Research Foundation of Guangdong Province","ror":null}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":52,"referenced_works":["https://openalex.org/W1994506733","https://openalex.org/W2062061704","https://openalex.org/W2072567873","https://openalex.org/W2288435061","https://openalex.org/W2565346753","https://openalex.org/W2606239549","https://openalex.org/W2968441064","https://openalex.org/W3016463754","https://openalex.org/W3023631077","https://openalex.org/W3080127600","https://openalex.org/W3093272460","https://openalex.org/W3196027478","https://openalex.org/W3199284680","https://openalex.org/W3209158005","https://openalex.org/W3209936538","https://openalex.org/W4289793055","https://openalex.org/W4295047702","https://openalex.org/W4296901580","https://openalex.org/W4312082954","https://openalex.org/W4320487989","https://openalex.org/W4320882953","https://openalex.org/W4366134172","https://openalex.org/W4367673612","https://openalex.org/W4368282472","https://openalex.org/W4380184651","https://openalex.org/W4385952190","https://openalex.org/W4389346516","https://openalex.org/W4390197746","https://openalex.org/W4391051342","https://openalex.org/W4391515408","https://openalex.org/W4392562772","https://openalex.org/W4393144087","https://openalex.org/W4393930924","https://openalex.org/W4394014366","https://openalex.org/W4394836984","https://openalex.org/W4394950993","https://openalex.org/W4403157517","https://openalex.org/W4404704617","https://openalex.org/W4404742269","https://openalex.org/W4405741159","https://openalex.org/W4408672774","https://openalex.org/W4409715947","https://openalex.org/W4409776300","https://openalex.org/W4410779875","https://openalex.org/W4410875281","https://openalex.org/W4412436860","https://openalex.org/W4412988896","https://openalex.org/W4416195997","https://openalex.org/W4417038646","https://openalex.org/W7141814277","https://openalex.org/W7163049714","https://openalex.org/W7197049956"],"related_works":["https://openalex.org/W4389936387","https://openalex.org/W7163567387","https://openalex.org/W7211889575","https://openalex.org/W2235791268","https://openalex.org/W7154451666","https://openalex.org/W7204757466","https://openalex.org/W4307794320","https://openalex.org/W7204636980","https://openalex.org/W7213867475","https://openalex.org/W4399267504"],"abstract_inverted_index":{"Flexible":[0],"wound":[1,30,143,152,167],"dressings":[2,168],"that":[3,42],"integrate":[4],"mechanical":[5,44,172],"compliance,":[6,45],"sensing":[7,80],"capability,":[8],"and":[9,47,50,89,97,116,128,134,154],"biological":[10,51],"functionality":[11,99],"remain":[12],"difficult":[13],"to":[14],"realize":[15],"without":[16,100],"compromising":[17,101],"structural":[18],"stability":[19],"or":[20],"signal":[21],"reliability.":[22],"This":[23,157],"work":[24,158],"reports":[25],"an":[26,160],"interface-engineered":[27,146],"biodegradable":[28,165],"nanofibrous":[29],"patch":[31,104],"based":[32],"on":[33],"a":[34,54,82,139],"carbon":[35],"nanotube/silver":[36],"nanoparticle":[37],"(CNT/Ag)":[38],"dual":[39,70],"conductive":[40,71],"network":[41,66],"integrates":[43],"electromechanical":[46],"thermal":[48],"sensing,":[49],"regulation":[52],"within":[53],"single":[55],"flexible":[56],"platform.":[57],"The":[58,103],"highly":[59],"elastic":[60],"poly(CL-co-TOSUO)":[61],"(PCT)":[62],"matrix":[63],"maintains":[64],"continuous":[65],"integrity.":[67],"Concurrently,":[68],"the":[69,75,145],"architecture":[72],"helps":[73],"alleviate":[74],"sensitivity-stretchability":[76],"trade-off,":[77],"enabling":[78],"stable":[79],"over":[81],"broad":[83],"deformation":[84],"range.":[85],"Polydopamine-mediated":[86],"interface":[87],"engineering":[88],"collagen":[90],"incorporation":[91],"enable":[92],"antibacterial":[93],"activity,":[94],"enhanced":[95],"hemostasis,":[96],"cell-interactive":[98],"stretchability.":[102],"exhibits":[105],"reproducible":[106],"resistance":[107],"responses":[108],"under":[109,170],"large":[110],"strain,":[111],"dynamic":[112,171],"loading,":[113],"cyclic":[114],"deformation,":[115],"wound-relevant":[117],"temperature":[118],"variations.":[119],"In":[120,138],"vitro":[121],"studies":[122],"demonstrate":[123],"effective":[124],"suppression":[125],"of":[126],"Gram-negative":[127],"Gram-positive":[129],"bacteria,":[130],"accelerated":[131],"blood":[132],"coagulation,":[133],"favorable":[135],"fibroblast":[136],"behavior.":[137],"rat":[140],"full-thickness":[141],"skin":[142],"model,":[144],"scaffold":[147],"shows":[148],"time-dependent":[149],"improvements":[150],"in":[151],"closure":[153],"tissue":[155],"regeneration.":[156],"establishes":[159],"interface-driven":[161],"materials":[162],"strategy":[163],"for":[164],"bioelectronic":[166],"operating":[169],"environments.":[173]},"counts_by_year":[],"updated_date":"2026-11-01T11:40:01.658920","created_date":"2026-10-30T00:00:00"}