{"id":"https://openalex.org/W7224321197","doi":"https://doi.org/10.3389/fped.2026.1991600","title":"The developing fetal immune landscape and congenital viral infection","display_name":"The developing fetal immune landscape and congenital viral infection","publication_year":2026,"publication_date":"2026-10-29","ids":{"openalex":"https://openalex.org/W7224321197","doi":"https://doi.org/10.3389/fped.2026.1991600"},"language":"en","primary_location":{"id":"doi:10.3389/fped.2026.1991600","doi":"https://doi.org/10.3389/fped.2026.1991600","is_oa":true,"landing_page_url":"https://doi.org/10.3389/fped.2026.1991600","pdf_url":"https://www.frontiersin.org/journals/pediatrics/articles/10.3389/fped.2026.1991600/pdf","source":{"id":"https://openalex.org/S2596117549","display_name":"Frontiers in Pediatrics","issn_l":"2296-2360","issn":["2296-2360"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","norway-1","poland-70","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320527","host_organization_name":"Frontiers Media","host_organization_lineage":["https://openalex.org/P4310320527"],"host_organization_lineage_names":["Frontiers Media"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in Pediatrics","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://www.frontiersin.org/journals/pediatrics/articles/10.3389/fped.2026.1991600/pdf","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5144251749","display_name":"Sophia C Chima","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I201448701","display_name":"University of Washington","ror":"https://ror.org/00cvxb145","country_code":"US","type":"education","lineage":["https://openalex.org/I201448701"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Sophia C. Chima","raw_affiliation_strings":["Department of Obstetrics and Gynecology, University of Washington School of Medicine"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Obstetrics and Gynecology, University of Washington School of Medicine","institution_ids":["https://openalex.org/I201448701"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5160134452","display_name":"Sidney J. Sun","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I201448701","display_name":"University of Washington","ror":"https://ror.org/00cvxb145","country_code":"US","type":"education","lineage":["https://openalex.org/I201448701"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Sidney J. Sun","raw_affiliation_strings":["Department of Obstetrics and Gynecology, University of Washington School of Medicine"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Obstetrics and Gynecology, University of Washington School of Medicine","institution_ids":["https://openalex.org/I201448701"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5152000196","display_name":"Tyla Duell","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I201448701","display_name":"University of Washington","ror":"https://ror.org/00cvxb145","country_code":"US","type":"education","lineage":["https://openalex.org/I201448701"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Tyla Duell","raw_affiliation_strings":["Department of Obstetrics and Gynecology, University of Washington School of Medicine"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Obstetrics and Gynecology, University of Washington School of Medicine","institution_ids":["https://openalex.org/I201448701"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5120005943","display_name":"Sasha Friese","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I201448701","display_name":"University of Washington","ror":"https://ror.org/00cvxb145","country_code":"US","type":"education","lineage":["https://openalex.org/I201448701"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Sasha Friese","raw_affiliation_strings":["Department of Obstetrics and Gynecology, University of Washington School of Medicine"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Obstetrics and Gynecology, University of Washington School of Medicine","institution_ids":["https://openalex.org/I201448701"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5152019522","display_name":"Vanshika Sindhu","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I201448701","display_name":"University of Washington","ror":"https://ror.org/00cvxb145","country_code":"US","type":"education","lineage":["https://openalex.org/I201448701"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Vanshika Sindhu","raw_affiliation_strings":["Department of Obstetrics and Gynecology, University of Washington School of Medicine"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Obstetrics and Gynecology, University of Washington School of Medicine","institution_ids":["https://openalex.org/I201448701"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5130805650","display_name":"Kristina Adams Waldorf","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I201448701","display_name":"University of Washington","ror":"https://ror.org/00cvxb145","country_code":"US","type":"education","lineage":["https://openalex.org/I201448701"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Kristina Adams Waldorf","raw_affiliation_strings":["Department of Obstetrics and Gynecology, University of Washington School of Medicine"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Obstetrics and Gynecology, University of Washington School of Medicine","institution_ids":["https://openalex.org/I201448701"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5130805650","https://openalex.org/A5144251749"],"corresponding_institution_ids":["https://openalex.org/I201448701"],"apc_list":{"value":3150,"currency":"CHF","value_usd":3801},"apc_paid":{"value":3150,"currency":"CHF","value_usd":3801},"fwci":0.0,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":{"value":0.77100215,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"14","issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11510","display_name":"Reproductive System and Pregnancy","score":0.30219998955726624,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11510","display_name":"Reproductive System and Pregnancy","score":0.30219998955726624,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T13410","display_name":"Immune responses and vaccinations","score":0.19210000336170197,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10031","display_name":"T-cell and B-cell Immunology","score":0.14390000700950623,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/fetal-immune-development","display_name":"fetal immune development","score":0.8199999928474426},{"id":"https://openalex.org/keywords/congenital-viral-infection","display_name":"congenital viral infection","score":0.8529999852180481},{"id":"https://openalex.org/keywords/innate-immunity","display_name":"innate immunity","score":0.7210000157356262},{"id":"https://openalex.org/keywords/adaptive-immunity","display_name":"adaptive immunity","score":0.847000002861023},{"id":"https://openalex.org/keywords/immune-ontogeny","display_name":"immune ontogeny","score":0.7559999823570251},{"id":"https://openalex.org/keywords/hematopoietic-stem-and-progenitor-cells","display_name":"hematopoietic stem and progenitor cells","score":0.8790000081062317},{"id":"https://openalex.org/keywords/vertical-transmission","display_name":"vertical transmission","score":0.6209999918937683},{"id":"https://openalex.org/keywords/intrauterine-growth-restriction","display_name":"fetal growth restriction","score":0.5690000057220459},{"id":"https://openalex.org/keywords/placenta","display_name":"placenta","score":0.6010000109672546},{"id":"https://openalex.org/keywords/fetal-brain","display_name":"fetal brain","score":0.6959999799728394},{"id":"https://openalex.org/keywords/fetal-liver","display_name":"fetal liver","score":0.6470000147819519},{"id":"https://openalex.org/keywords/fetal-thymus","display_name":"fetal thymus","score":0.8629999756813049},{"id":"https://openalex.org/keywords/fetal-bone-marrow","display_name":"fetal bone marrow","score":0.7590000033378601},{"id":"https://openalex.org/keywords/fetal-spleen","display_name":"fetal spleen","score":0.9110000133514404},{"id":"https://openalex.org/keywords/immune-tolerance","display_name":"immune tolerance","score":0.7229999899864197},{"id":"https://openalex.org/keywords/adverse-obstetric-outcomes","display_name":"adverse obstetric outcomes","score":0.621999979019165}],"concepts":[{"id":"https://openalex.org/C8891405","wikidata":"https://www.wikidata.org/wiki/Q1059","display_name":"Immune system","level":2,"score":0.8328999876976013},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.6937000155448914},{"id":"https://openalex.org/C172680121","wikidata":"https://www.wikidata.org/wiki/Q26513","display_name":"Fetus","level":3,"score":0.6298999786376953},{"id":"https://openalex.org/C136449434","wikidata":"https://www.wikidata.org/wiki/Q428253","display_name":"Innate immune system","level":3,"score":0.6155999898910522},{"id":"https://openalex.org/C2777422395","wikidata":"https://www.wikidata.org/wiki/Q3149136","display_name":"Immunocompetence","level":3,"score":0.6086999773979187},{"id":"https://openalex.org/C193419808","wikidata":"https://www.wikidata.org/wiki/Q1645075","display_name":"Acquired immune system","level":3,"score":0.600600004196167},{"id":"https://openalex.org/C2779341262","wikidata":"https://www.wikidata.org/wiki/Q182581","display_name":"Immunity","level":3,"score":0.48339998722076416},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.4616999924182892},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.43810001015663147},{"id":"https://openalex.org/C109159458","wikidata":"https://www.wikidata.org/wiki/Q919283","display_name":"Haematopoiesis","level":3,"score":0.41670000553131104},{"id":"https://openalex.org/C201750760","wikidata":"https://www.wikidata.org/wiki/Q1896218","display_name":"Progenitor cell","level":3,"score":0.30880001187324524},{"id":"https://openalex.org/C28328180","wikidata":"https://www.wikidata.org/wiki/Q48196","display_name":"Stem cell","level":2,"score":0.29339998960494995},{"id":"https://openalex.org/C2778086970","wikidata":"https://www.wikidata.org/wiki/Q514525","display_name":"Hematopoietic stem cell","level":4,"score":0.28790000081062317},{"id":"https://openalex.org/C47742525","wikidata":"https://www.wikidata.org/wiki/Q13418826","display_name":"Innate lymphoid cell","level":4,"score":0.2671000063419342},{"id":"https://openalex.org/C2776090121","wikidata":"https://www.wikidata.org/wiki/Q193529","display_name":"T cell","level":3,"score":0.26260000467300415},{"id":"https://openalex.org/C2779234561","wikidata":"https://www.wikidata.org/wiki/Q11995","display_name":"Pregnancy","level":2,"score":0.2556999921798706},{"id":"https://openalex.org/C137993225","wikidata":"https://www.wikidata.org/wiki/Q6058723","display_name":"Intrinsic immunity","level":4,"score":0.251800000667572},{"id":"https://openalex.org/C2780007613","wikidata":"https://www.wikidata.org/wiki/Q546523","display_name":"Bone marrow","level":2,"score":0.2513999938964844}],"mesh":[],"locations_count":2,"locations":[{"id":"doi:10.3389/fped.2026.1991600","doi":"https://doi.org/10.3389/fped.2026.1991600","is_oa":true,"landing_page_url":"https://doi.org/10.3389/fped.2026.1991600","pdf_url":"https://www.frontiersin.org/journals/pediatrics/articles/10.3389/fped.2026.1991600/pdf","source":{"id":"https://openalex.org/S2596117549","display_name":"Frontiers in Pediatrics","issn_l":"2296-2360","issn":["2296-2360"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","norway-1","poland-70","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320527","host_organization_name":"Frontiers Media","host_organization_lineage":["https://openalex.org/P4310320527"],"host_organization_lineage_names":["Frontiers Media"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in Pediatrics","raw_type":"journal-article"},{"id":"pmh:oai:doaj.org/article:d7c37f8d9a7b4949b0298e2dd1579dba","doi":null,"is_oa":false,"landing_page_url":"https://doaj.org/article/d7c37f8d9a7b4949b0298e2dd1579dba","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Frontiers in Pediatrics, Vol 14 (2026)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.3389/fped.2026.1991600","doi":"https://doi.org/10.3389/fped.2026.1991600","is_oa":true,"landing_page_url":"https://doi.org/10.3389/fped.2026.1991600","pdf_url":"https://www.frontiersin.org/journals/pediatrics/articles/10.3389/fped.2026.1991600/pdf","source":{"id":"https://openalex.org/S2596117549","display_name":"Frontiers in Pediatrics","issn_l":"2296-2360","issn":["2296-2360"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","norway-1","poland-70","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320527","host_organization_name":"Frontiers Media","host_organization_lineage":["https://openalex.org/P4310320527"],"host_organization_lineage_names":["Frontiers Media"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in Pediatrics","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.9763000011444092}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337355","display_name":"National Institute of Allergy and Infectious Diseases","ror":"https://ror.org/043z4tv69"},{"id":"https://openalex.org/F4320337364","display_name":"National Institute of Child Health and Human Development","ror":"https://ror.org/04byxyr05"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W7224321197.pdf","grobid_xml":"https://content.openalex.org/works/W7224321197.grobid-xml"},"referenced_works_count":126,"referenced_works":["https://openalex.org/W34434364","https://openalex.org/W1512693074","https://openalex.org/W1937405158","https://openalex.org/W1937527608","https://openalex.org/W1967416722","https://openalex.org/W1971246106","https://openalex.org/W1973976214","https://openalex.org/W1983598990","https://openalex.org/W1983609489","https://openalex.org/W1986875328","https://openalex.org/W1991689171","https://openalex.org/W1991849405","https://openalex.org/W1997131126","https://openalex.org/W2001056499","https://openalex.org/W2008582581","https://openalex.org/W2016870461","https://openalex.org/W2023990790","https://openalex.org/W2025890371","https://openalex.org/W2026515510","https://openalex.org/W2029190354","https://openalex.org/W2029888713","https://openalex.org/W2041311243","https://openalex.org/W2044201812","https://openalex.org/W2046634287","https://openalex.org/W2054919518","https://openalex.org/W2061170290","https://openalex.org/W2072066004","https://openalex.org/W2076593960","https://openalex.org/W2077962599","https://openalex.org/W2088657555","https://openalex.org/W2090320337","https://openalex.org/W2093042038","https://openalex.org/W2093060517","https://openalex.org/W2099151586","https://openalex.org/W2120426862","https://openalex.org/W2122546244","https://openalex.org/W2122956735","https://openalex.org/W2125041033","https://openalex.org/W2125679885","https://openalex.org/W2128303660","https://openalex.org/W2133657835","https://openalex.org/W2133963802","https://openalex.org/W2137711689","https://openalex.org/W2144625807","https://openalex.org/W2152582437","https://openalex.org/W2154673881","https://openalex.org/W2159934585","https://openalex.org/W2160849060","https://openalex.org/W2169189116","https://openalex.org/W2295245778","https://openalex.org/W2323062796","https://openalex.org/W2326233293","https://openalex.org/W2395416726","https://openalex.org/W2400827254","https://openalex.org/W2503872635","https://openalex.org/W2515448189","https://openalex.org/W2580172796","https://openalex.org/W2581199190","https://openalex.org/W2598783947","https://openalex.org/W2602095193","https://openalex.org/W2609460893","https://openalex.org/W2613031442","https://openalex.org/W2625822122","https://openalex.org/W2735712510","https://openalex.org/W2757992727","https://openalex.org/W2778279659","https://openalex.org/W2782327081","https://openalex.org/W2800025479","https://openalex.org/W2800578026","https://openalex.org/W2805118976","https://openalex.org/W2809259575","https://openalex.org/W2908761681","https://openalex.org/W2924921114","https://openalex.org/W2946147773","https://openalex.org/W2949030426","https://openalex.org/W2964973553","https://openalex.org/W2980292232","https://openalex.org/W2990266583","https://openalex.org/W2990911496","https://openalex.org/W3002591206","https://openalex.org/W3006781275","https://openalex.org/W3013558569","https://openalex.org/W3015830199","https://openalex.org/W3027100209","https://openalex.org/W3033714866","https://openalex.org/W3046622690","https://openalex.org/W3085636544","https://openalex.org/W3092854319","https://openalex.org/W3114485724","https://openalex.org/W3172575896","https://openalex.org/W3181618064","https://openalex.org/W3184970938","https://openalex.org/W3194381721","https://openalex.org/W3203091379","https://openalex.org/W3203597352","https://openalex.org/W3204931394","https://openalex.org/W4200536663","https://openalex.org/W4211063468","https://openalex.org/W4214629326","https://openalex.org/W4214834735","https://openalex.org/W4224434437","https://openalex.org/W4248368453","https://openalex.org/W4280578638","https://openalex.org/W4292056881","https://openalex.org/W4293724332","https://openalex.org/W4301398506","https://openalex.org/W4308074641","https://openalex.org/W4312125451","https://openalex.org/W4377692714","https://openalex.org/W4382468401","https://openalex.org/W4384664721","https://openalex.org/W4393161822","https://openalex.org/W4396585734","https://openalex.org/W4396659238","https://openalex.org/W4401464008","https://openalex.org/W4403458585","https://openalex.org/W4403607080","https://openalex.org/W4405416306","https://openalex.org/W4406338636","https://openalex.org/W4407251444","https://openalex.org/W4407989346","https://openalex.org/W4410130037","https://openalex.org/W4410601308","https://openalex.org/W4413020552","https://openalex.org/W4415619687","https://openalex.org/W7167366743"],"related_works":["https://openalex.org/W2982083094","https://openalex.org/W2411456541","https://openalex.org/W4206827140","https://openalex.org/W7214587280","https://openalex.org/W3023140579","https://openalex.org/W2596227297","https://openalex.org/W4308309506","https://openalex.org/W2920794476","https://openalex.org/W1857069017","https://openalex.org/W4399682068"],"abstract_inverted_index":{"Fetal":[0],"development":[1,72],"is":[2,28,45,87,158],"a":[3,29],"complex":[4],"process":[5],"that":[6,187],"can":[7],"lead":[8],"to":[9,75,88],"adverse":[10,76],"health":[11],"consequences":[12],"when":[13,160],"impaired,":[14],"such":[15],"as":[16],"congenital":[17],"anomalies,":[18],"fetal":[19,71,97,130],"growth":[20],"restriction,":[21],"preterm":[22],"birth,":[23],"and":[24,50,73,78,99,105,119,137,146,155,168,175],"stillbirth.":[25],"Although":[26],"there":[27],"well-developed":[30],"literature":[31],"on":[32],"the":[33,41,48,54,82,93,96,114,129,182],"timing":[34],"of":[35,53,66,84,92,95,116,150],"adaptive":[36,98],"immune":[37,56,101,126,144,174,185],"cell":[38],"appearance":[39],"in":[40,125,143,153],"fetus,":[42],"comparatively":[43],"little":[44],"known":[46],"about":[47],"ontogeny":[49,94],"functional":[51],"maturation":[52],"innate":[55,100,151],"system":[57],"over":[58],"gestation.":[59,190],"This":[60],"knowledge":[61,91],"gap":[62],"limits":[63],"our":[64],"understanding":[65],"how":[67,106,165],"intrauterine":[68],"infections":[69,171],"influence":[70],"contribute":[74],"obstetric":[77],"neonatal":[79],"outcomes.":[80],"Thus,":[81],"goal":[83],"this":[85],"review":[86],"summarize":[89],"existing":[90],"systems":[102],"throughout":[103,189],"gestation,":[104],"they":[107],"are":[108],"impacted":[109],"by":[110],"infection.":[111],"We":[112],"examine":[113],"emergence":[115],"hematopoietic":[117],"stem":[118],"progenitor":[120],"cells,":[121],"while":[122],"highlighting":[123],"changes":[124],"lineages":[127],"across":[128],"brain,":[131],"liver,":[132],"thymus,":[133],"bone":[134],"marrow,":[135],"spleen,":[136],"placenta,":[138],"which":[139],"play":[140],"critical":[141],"roles":[142],"competency":[145],"tolerance.":[147],"The":[148],"role":[149],"immunity":[152],"immunocompetence":[154],"pathogen":[156],"responses":[157],"highlighted":[159],"known.":[161],"Finally,":[162],"we":[163],"address":[164],"vertically":[166],"transmitted":[167],"teratogenic":[169],"viral":[170],"disrupt":[172],"normal":[173],"tissue":[176],"development.":[177],"Collectively,":[178],"these":[179],"studies":[180],"demonstrate":[181],"dynamic,":[183],"tissue-specific":[184],"landscape":[186],"evolves":[188]},"counts_by_year":[],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2026-10-30T00:00:00"}
