{"id":"https://openalex.org/W7224205358","doi":"https://doi.org/10.3390/nu18213574","title":"Gene\u2013Nutrition Interaction in Gastric Cancer: miRNA-Related Polymorphisms in CTSF and NT5E, Dietary Exposures, and Site-Specific Risk","display_name":"Gene\u2013Nutrition Interaction in Gastric Cancer: miRNA-Related Polymorphisms in CTSF and NT5E, Dietary Exposures, and Site-Specific Risk","publication_year":2026,"publication_date":"2026-10-29","ids":{"openalex":"https://openalex.org/W7224205358","doi":"https://doi.org/10.3390/nu18213574"},"language":"en","primary_location":{"id":"doi:10.3390/nu18213574","doi":"https://doi.org/10.3390/nu18213574","is_oa":true,"landing_page_url":"https://doi.org/10.3390/nu18213574","pdf_url":null,"source":{"id":"https://openalex.org/S110785341","display_name":"Nutrients","issn_l":"2072-6643","issn":["2072-6643"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nutrients","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://doi.org/10.3390/nu18213574","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5072249876","display_name":"Dan Wang","orcid":"https://orcid.org/0000-0002-5638-6112","observed_orcids":["https://orcid.org/0000-0002-5638-6112"]},"institutions":[{"id":"https://openalex.org/I129708740","display_name":"Fujian Medical University","ror":"https://ror.org/050s6ns64","country_code":"CN","type":"education","lineage":["https://openalex.org/I129708740"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Dan Wang","raw_affiliation_strings":["Department of Preventive Medicine, School of Public Health, Fujian Medical University, Fuzhou 350122, China","Key Laboratory of Environment and Health, Fujian Province University, Fuzhou 350122, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Preventive Medicine, School of Public Health, Fujian Medical University, Fuzhou 350122, China","institution_ids":["https://openalex.org/I129708740"]},{"raw_affiliation_string":"Key Laboratory of Environment and Health, Fujian Province University, Fuzhou 350122, China","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100633483","display_name":"Shilin Chen","orcid":"https://orcid.org/0000-0001-9239-7655","observed_orcids":["https://orcid.org/0000-0001-9239-7655","https://orcid.org/0009-0004-6418-1872"]},"institutions":[{"id":"https://openalex.org/I129708740","display_name":"Fujian Medical University","ror":"https://ror.org/050s6ns64","country_code":"CN","type":"education","lineage":["https://openalex.org/I129708740"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Shilin Chen","raw_affiliation_strings":["Department of Preventive Medicine, School of Public Health, Fujian Medical University, Fuzhou 350122, China","Key Laboratory of Environment and Health, Fujian Province University, Fuzhou 350122, China"],"raw_orcid":"https://orcid.org/0009-0004-6418-1872","affiliations":[{"raw_affiliation_string":"Department of Preventive Medicine, School of Public Health, Fujian Medical University, Fuzhou 350122, China","institution_ids":["https://openalex.org/I129708740"]},{"raw_affiliation_string":"Key Laboratory of Environment and Health, Fujian Province University, Fuzhou 350122, China","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100542575","display_name":"Li Yalan","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I129708740","display_name":"Fujian Medical University","ror":"https://ror.org/050s6ns64","country_code":"CN","type":"education","lineage":["https://openalex.org/I129708740"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yalan Li","raw_affiliation_strings":["Department of Preventive Medicine, School of Public Health, Fujian Medical University, Fuzhou 350122, China","Key Laboratory of Environment and Health, Fujian Province University, Fuzhou 350122, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Preventive Medicine, School of Public Health, Fujian Medical University, Fuzhou 350122, China","institution_ids":["https://openalex.org/I129708740"]},{"raw_affiliation_string":"Key Laboratory of Environment and Health, Fujian Province University, Fuzhou 350122, China","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5160126005","display_name":"Ruoyu Li","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I129708740","display_name":"Fujian Medical University","ror":"https://ror.org/050s6ns64","country_code":"CN","type":"education","lineage":["https://openalex.org/I129708740"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Ruoyu Li","raw_affiliation_strings":["Department of Preventive Medicine, School of Public Health, Fujian Medical University, Fuzhou 350122, China","Key Laboratory of Environment and Health, Fujian Province University, Fuzhou 350122, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Preventive Medicine, School of Public Health, Fujian Medical University, Fuzhou 350122, China","institution_ids":["https://openalex.org/I129708740"]},{"raw_affiliation_string":"Key Laboratory of Environment and Health, Fujian Province University, Fuzhou 350122, China","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5123302427","display_name":"Peifang Liu","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I129708740","display_name":"Fujian Medical University","ror":"https://ror.org/050s6ns64","country_code":"CN","type":"education","lineage":["https://openalex.org/I129708740"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Peifang Liu","raw_affiliation_strings":["Department of Preventive Medicine, School of Public Health, Fujian Medical University, Fuzhou 350122, China","Key Laboratory of Environment and Health, Fujian Province University, Fuzhou 350122, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Preventive Medicine, School of Public Health, Fujian Medical University, Fuzhou 350122, China","institution_ids":["https://openalex.org/I129708740"]},{"raw_affiliation_string":"Key Laboratory of Environment and Health, Fujian Province University, Fuzhou 350122, China","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5090610975","display_name":"Yu Jiang","orcid":"https://orcid.org/0000-0003-4045-1634","observed_orcids":["https://orcid.org/0000-0003-4045-1634"]},"institutions":[{"id":"https://openalex.org/I129708740","display_name":"Fujian Medical University","ror":"https://ror.org/050s6ns64","country_code":"CN","type":"education","lineage":["https://openalex.org/I129708740"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yu Jiang","raw_affiliation_strings":["Department of Preventive Medicine, School of Public Health, Fujian Medical University, Fuzhou 350122, China","Key Laboratory of Environment and Health, Fujian Province University, Fuzhou 350122, China"],"raw_orcid":"https://orcid.org/0000-0003-4045-1634","affiliations":[{"raw_affiliation_string":"Department of Preventive Medicine, School of Public Health, Fujian Medical University, Fuzhou 350122, China","institution_ids":["https://openalex.org/I129708740"]},{"raw_affiliation_string":"Key Laboratory of Environment and Health, Fujian Province University, Fuzhou 350122, China","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5102762174","display_name":"Jianjun Xiang","orcid":"https://orcid.org/0000-0001-8107-2580","observed_orcids":["https://orcid.org/0000-0001-8107-2580"]},"institutions":[{"id":"https://openalex.org/I129708740","display_name":"Fujian Medical University","ror":"https://ror.org/050s6ns64","country_code":"CN","type":"education","lineage":["https://openalex.org/I129708740"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Jianjun Xiang","raw_affiliation_strings":["Department of Preventive Medicine, School of Public Health, Fujian Medical University, Fuzhou 350122, China","Key Laboratory of Environment and Health, Fujian Province University, Fuzhou 350122, China"],"raw_orcid":"https://orcid.org/0000-0001-8107-2580","affiliations":[{"raw_affiliation_string":"Department of Preventive Medicine, School of Public Health, Fujian Medical University, Fuzhou 350122, China","institution_ids":["https://openalex.org/I129708740"]},{"raw_affiliation_string":"Key Laboratory of Environment and Health, Fujian Province University, Fuzhou 350122, China","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5160073552","display_name":"Wei Yan","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Wei Yan","raw_affiliation_strings":["The First Hospital of Putian City, Putian 351100, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The First Hospital of Putian City, Putian 351100, China","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5059581979","display_name":"Chuancheng Wu","orcid":"https://orcid.org/0000-0003-2101-4738","observed_orcids":["https://orcid.org/0000-0003-2101-4738","https://orcid.org/0009-0002-6773-0780"]},"institutions":[{"id":"https://openalex.org/I129708740","display_name":"Fujian Medical University","ror":"https://ror.org/050s6ns64","country_code":"CN","type":"education","lineage":["https://openalex.org/I129708740"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Chuancheng Wu","raw_affiliation_strings":["Department of Preventive Medicine, School of Public Health, Fujian Medical University, Fuzhou 350122, China","Key Laboratory of Environment and Health, Fujian Province University, Fuzhou 350122, China"],"raw_orcid":"https://orcid.org/0000-0003-2101-4738","affiliations":[{"raw_affiliation_string":"Department of Preventive Medicine, School of Public Health, Fujian Medical University, Fuzhou 350122, China","institution_ids":["https://openalex.org/I129708740"]},{"raw_affiliation_string":"Key Laboratory of Environment and Health, Fujian Province University, Fuzhou 350122, China","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5059581979","https://openalex.org/A5160073552"],"corresponding_institution_ids":["https://openalex.org/I129708740"],"apc_list":{"value":2900,"currency":"CHF","value_usd":3499},"apc_paid":{"value":2900,"currency":"CHF","value_usd":3499},"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.82806242,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"18","issue":"21","first_page":"3574","last_page":"3574"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10062","display_name":"MicroRNA in disease regulation","score":0.5541999936103821,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10062","display_name":"MicroRNA in disease regulation","score":0.5541999936103821,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10276","display_name":"Helicobacter pylori-related gastroenterology studies","score":0.23559999465942383,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T13984","display_name":"Nutrition, Genetics, and Disease","score":0.09440000355243683,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/gastric-cancer","display_name":"gastric cancer","score":0.9980000257492065},{"id":"https://openalex.org/keywords/nt5e","display_name":"NT5E","score":0.9909999966621399},{"id":"https://openalex.org/keywords/mir-30a","display_name":"miR-30a","score":0.9240000247955322},{"id":"https://openalex.org/keywords/dietary-exposure","display_name":"dietary exposure","score":0.5609999895095825},{"id":"https://openalex.org/keywords/gastric-cardia-cancer","display_name":"gastric cardia cancer","score":0.8539999723434448},{"id":"https://openalex.org/keywords/cancer-risk","display_name":"cancer risk","score":0.5400000214576721}],"concepts":[{"id":"https://openalex.org/C25249476","wikidata":"https://www.wikidata.org/wiki/Q6934678","display_name":"Multifactor dimensionality reduction","level":5,"score":0.897599995136261},{"id":"https://openalex.org/C153209595","wikidata":"https://www.wikidata.org/wiki/Q501128","display_name":"Single-nucleotide polymorphism","level":4,"score":0.7148000001907349},{"id":"https://openalex.org/C151956035","wikidata":"https://www.wikidata.org/wiki/Q1132755","display_name":"Logistic regression","level":2,"score":0.6983000040054321},{"id":"https://openalex.org/C2779662715","wikidata":"https://www.wikidata.org/wiki/Q19596443","display_name":"Conditional logistic regression","level":3,"score":0.6315000057220459},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.5889000296592712},{"id":"https://openalex.org/C2781249084","wikidata":"https://www.wikidata.org/wiki/Q908656","display_name":"Preference","level":2,"score":0.47859999537467957},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.4636000096797943},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.4401000142097473},{"id":"https://openalex.org/C855514","wikidata":"https://www.wikidata.org/wiki/Q1665869","display_name":"Interaction","level":2,"score":0.3813999891281128},{"id":"https://openalex.org/C139275648","wikidata":"https://www.wikidata.org/wiki/Q17134011","display_name":"SNP","level":5,"score":0.38029998540878296},{"id":"https://openalex.org/C143998085","wikidata":"https://www.wikidata.org/wiki/Q162555","display_name":"Oncology","level":1,"score":0.37869998812675476},{"id":"https://openalex.org/C146304588","wikidata":"https://www.wikidata.org/wiki/Q961652","display_name":"Case-control study","level":2,"score":0.3336000144481659},{"id":"https://openalex.org/C180754005","wikidata":"https://www.wikidata.org/wiki/Q80726","display_name":"Allele","level":3,"score":0.310699999332428},{"id":"https://openalex.org/C2993967602","wikidata":"https://www.wikidata.org/wiki/Q5532932","display_name":"Genetic variants","level":4,"score":0.290800005197525},{"id":"https://openalex.org/C2909999518","wikidata":"https://www.wikidata.org/wiki/Q1029907","display_name":"GASTRIC CARDIA","level":4,"score":0.2824000120162964},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.27799999713897705},{"id":"https://openalex.org/C3017650416","wikidata":"https://www.wikidata.org/wiki/Q3281331","display_name":"Feeding behavior","level":2,"score":0.2736000120639801},{"id":"https://openalex.org/C186413461","wikidata":"https://www.wikidata.org/wiki/Q744727","display_name":"Genetic association","level":5,"score":0.26820001006126404},{"id":"https://openalex.org/C135763542","wikidata":"https://www.wikidata.org/wiki/Q106016","display_name":"Genotype","level":3,"score":0.2653999924659729},{"id":"https://openalex.org/C130947863","wikidata":"https://www.wikidata.org/wiki/Q5533121","display_name":"Gene\u2013environment interaction","level":4,"score":0.2630000114440918},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.2587999999523163},{"id":"https://openalex.org/C60644358","wikidata":"https://www.wikidata.org/wiki/Q128570","display_name":"Bioinformatics","level":1,"score":0.2529999911785126}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.3390/nu18213574","doi":"https://doi.org/10.3390/nu18213574","is_oa":true,"landing_page_url":"https://doi.org/10.3390/nu18213574","pdf_url":null,"source":{"id":"https://openalex.org/S110785341","display_name":"Nutrients","issn_l":"2072-6643","issn":["2072-6643"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nutrients","raw_type":"journal-article"}],"best_oa_location":{"id":"doi:10.3390/nu18213574","doi":"https://doi.org/10.3390/nu18213574","is_oa":true,"landing_page_url":"https://doi.org/10.3390/nu18213574","pdf_url":null,"source":{"id":"https://openalex.org/S110785341","display_name":"Nutrients","issn_l":"2072-6643","issn":["2072-6643"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nutrients","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":1.0,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[],"funders":[{"id":"https://openalex.org/F4320323190","display_name":"Fujian Provincial Department of Science and Technology","ror":"https://ror.org/00rgzpv08"},{"id":"https://openalex.org/F4320328113","display_name":"Fujian Medical University","ror":"https://ror.org/050s6ns64"},{"id":"https://openalex.org/F4320336588","display_name":"Fujian Provincial Health Technology Project","ror":null}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":45,"referenced_works":["https://openalex.org/W1563316806","https://openalex.org/W1975600230","https://openalex.org/W1976634586","https://openalex.org/W1980263659","https://openalex.org/W2082791291","https://openalex.org/W2141638857","https://openalex.org/W2162425895","https://openalex.org/W2178408458","https://openalex.org/W2280504966","https://openalex.org/W2282263597","https://openalex.org/W2740042480","https://openalex.org/W2907841219","https://openalex.org/W2924460699","https://openalex.org/W2997804362","https://openalex.org/W3069136166","https://openalex.org/W3107074523","https://openalex.org/W3138512260","https://openalex.org/W4220998335","https://openalex.org/W4221038986","https://openalex.org/W4224321569","https://openalex.org/W4281391945","https://openalex.org/W4281839057","https://openalex.org/W4308510074","https://openalex.org/W4318042053","https://openalex.org/W4360611401","https://openalex.org/W4393222443","https://openalex.org/W4399122894","https://openalex.org/W4399578543","https://openalex.org/W4400223060","https://openalex.org/W4401032065","https://openalex.org/W4402432673","https://openalex.org/W4402777618","https://openalex.org/W4402929903","https://openalex.org/W4407025454","https://openalex.org/W4409508147","https://openalex.org/W4410732162","https://openalex.org/W4412391233","https://openalex.org/W4414011323","https://openalex.org/W4415680691","https://openalex.org/W7119501295","https://openalex.org/W7124173782","https://openalex.org/W7125520973","https://openalex.org/W7136034905","https://openalex.org/W7166643638","https://openalex.org/W7169833601"],"related_works":["https://openalex.org/W2343523410","https://openalex.org/W7096899850","https://openalex.org/W2340087958","https://openalex.org/W4206537709","https://openalex.org/W2069713744","https://openalex.org/W2162710411","https://openalex.org/W2997623499","https://openalex.org/W2894375933","https://openalex.org/W1645677503","https://openalex.org/W2096812786"],"abstract_inverted_index":{"Background:":[0],"Gastric":[1],"cancer":[2,9],"(GC)":[3],"is":[4],"a":[5,70,242],"leading":[6],"cause":[7],"of":[8,140],"death":[10],"in":[11,14,33,50,73,89,195,200,206,249],"China,":[12],"particularly":[13],"rural":[15],"high-incidence":[16,71],"areas.":[17],"miRNA-related":[18,31,77,193],"SNPs":[19,32,78],"may":[20],"interact":[21],"with":[22,39,47,114,125,137,180],"diet":[23],"to":[24,84,104,241],"influence":[25],"GC":[26,64,119,130,142],"risk.":[27,120],"We":[28],"therefore":[29],"examined":[30],"COPS2,":[34],"CTSF,":[35],"and":[36,43,53,66,81,96,107,117,128,151,169,197,199,237],"NT5E,":[37],"together":[38],"their":[40,45],"cognate":[41],"miRNAs,":[42],"assessed":[44],"interactions":[46],"dietary":[48,256],"factors":[49],"overall,":[51],"cardia,":[52],"non-cardia":[54,118],"GC.":[55,160],"Methods:":[56],"A":[57,161],"1:1":[58],"matched":[59],"case-control":[60],"study":[61],"included":[62,88],"550":[63,67],"cases":[65],"controls":[68],"from":[69],"county":[72],"Fujian,":[74],"China.":[75],"Eight":[76],"were":[79,87,102],"genotyped,":[80],"seven":[82],"conforming":[83],"Hardy\u2013Weinberg":[85],"equilibrium":[86],"the":[90,154,230],"final":[91],"analysis.":[92],"Conditional":[93],"logistic":[94],"regression":[95],"generalized":[97],"multifactor":[98],"dimensionality":[99],"reduction":[100],"(GMDR)":[101],"used":[103],"assess":[105],"associations":[106],"interactions.":[108],"Results:":[109],"CTSF":[110,196],"rs4576":[111,152,168,236],"was":[112,123,135,165],"associated":[113,124,136],"increased":[115,126,138],"overall":[116,127,159],"NT5E":[121,198],"rs6913634":[122],"cardia":[129,141],"risk,":[131],"whereas":[132],"miR-30a":[133,201],"rs2222722":[134],"risk":[139],"only.":[143],"GMDR":[144],"identified":[145],"hard-food":[146,170,181,238],"preference,":[147],"pickled":[148,184],"vegetable":[149,185],"intake,":[150],"as":[153,221],"best":[155],"interaction":[156,164,234,245],"model":[157],"for":[158],"positive":[162,232],"additive":[163,233],"observed":[166,222],"between":[167,235],"preference":[171,182,239],"(RERI":[172],"=":[173],"1.65,":[174],"95%":[175],"CI:":[176],"0.049\u20133.26).":[177],"G-allele":[178],"carriers":[179],"or":[183],"intake":[186],"had":[187],"markedly":[188],"elevated":[189],"joint":[190],"risks.":[191],"Conclusions:":[192],"polymorphisms":[194],"showed":[202],"subsite-related":[203],"association":[204],"patterns":[205,223],"this":[207],"high-risk":[208],"Chinese":[209],"population;":[210],"however,":[211],"without":[212],"formal":[213],"between-subsite":[214],"heterogeneity":[215],"tests,":[216],"these":[217],"should":[218],"be":[219],"interpreted":[220],"rather":[224],"than":[225],"established":[226],"subtype-specific":[227],"differences.":[228],"Additionally,":[229],"preliminary":[231],"points":[240],"potential":[243],"gene\u2013diet":[244],"that":[246],"warrants":[247],"validation":[248],"independent":[250],"populations":[251],"before":[252],"it":[253],"can":[254],"inform":[255],"prevention.":[257]},"counts_by_year":[],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2026-10-30T00:00:00"}