{"id":"https://openalex.org/W7224126359","doi":"https://doi.org/10.1016/j.celrep.2026.118190","title":"Sleep-dependent DNA methylation remodeling in basolateral amygdala fear engrams","display_name":"Sleep-dependent DNA methylation remodeling in basolateral amygdala fear engrams","publication_year":2026,"publication_date":"2026-10-28","ids":{"openalex":"https://openalex.org/W7224126359","doi":"https://doi.org/10.1016/j.celrep.2026.118190","pmid":"https://pubmed.ncbi.nlm.nih.gov/42949914"},"language":"en","primary_location":{"id":"doi:10.1016/j.celrep.2026.118190","doi":"https://doi.org/10.1016/j.celrep.2026.118190","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.celrep.2026.118190","pdf_url":"https://www.cell.com/cell-reports/pdf/S2211-1247(26)01269-6.pdf","source":{"id":"https://openalex.org/S169236886","display_name":"Cell Reports","issn_l":"2211-1247","issn":["2211-1247","2639-1856"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-b","doyens","jufo-3","ki-jl-2","medline","norway-2","oarl","poland-200","vabb-shw"],"host_organization":"https://openalex.org/P4310315673","host_organization_name":"Cell Press","host_organization_lineage":["https://openalex.org/P4310315673","https://openalex.org/P4310320990"],"host_organization_lineage_names":["Cell Press","Elsevier BV"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cell Reports","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://www.cell.com/cell-reports/pdf/S2211-1247(26)01269-6.pdf","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5159999662","display_name":"Xinyue Chen","orcid":"https://orcid.org/0000-0003-0264-1488","observed_orcids":["https://orcid.org/0000-0003-0264-1488"]},"institutions":[{"id":"https://openalex.org/I2799503643","display_name":"Columbia University Irving Medical Center","ror":"https://ror.org/01esghr10","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2799503643"]},{"id":"https://openalex.org/I78577930","display_name":"Columbia University","ror":"https://ror.org/00hj8s172","country_code":"US","type":"education","lineage":["https://openalex.org/I78577930"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Xinyue Chen","raw_affiliation_strings":["Department of Neuroscience, Vagelos College of Physicians and Surgeons, Columbia University Medical Center, Columbia University, New York, NY 10032, USA; Department of Neurology, Vagelos College of Physicians and Surgeons, Columbia University, New York, NY 10032, USA; Department of Physiology and Cellular Biophysics, Vagelos College of Physicians and Surgeons, Columbia University Medical Center, Columbia University, New York, NY 10032, USA"],"raw_orcid":"https://orcid.org/0000-0003-0264-1488","affiliations":[{"raw_affiliation_string":"Department of Neuroscience, Vagelos College of Physicians and Surgeons, Columbia University Medical Center, Columbia University, New York, NY 10032, USA; Department of Neurology, Vagelos College of Physicians and Surgeons, Columbia University, New York, NY 10032, USA; Department of Physiology and Cellular Biophysics, Vagelos College of Physicians and Surgeons, Columbia University Medical Center, Columbia University, New York, NY 10032, USA","institution_ids":["https://openalex.org/I2799503643","https://openalex.org/I78577930"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5079167083","display_name":"Fanwei Ruan","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I181547552","display_name":"Baylor College of Medicine","ror":"https://ror.org/02pttbw34","country_code":"US","type":"education","lineage":["https://openalex.org/I181547552","https://openalex.org/I2801539370"]},{"id":"https://openalex.org/I2799503643","display_name":"Columbia University Irving Medical Center","ror":"https://ror.org/01esghr10","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2799503643"]},{"id":"https://openalex.org/I78577930","display_name":"Columbia University","ror":"https://ror.org/00hj8s172","country_code":"US","type":"education","lineage":["https://openalex.org/I78577930"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Fanwei Ruan","raw_affiliation_strings":["Graduate Program in Quantitative and Computational Biosciences, Baylor College of Medicine, Houston, TX 77030, USA; Department of Physiology and Cellular Biophysics, Vagelos College of Physicians and Surgeons, Columbia University Medical Center, Columbia University, New York, NY 10032, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Graduate Program in Quantitative and Computational Biosciences, Baylor College of Medicine, Houston, TX 77030, USA; Department of Physiology and Cellular Biophysics, Vagelos College of Physicians and Surgeons, Columbia University Medical Center, Columbia University, New York, NY 10032, USA","institution_ids":["https://openalex.org/I181547552","https://openalex.org/I2799503643","https://openalex.org/I78577930"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5160007408","display_name":"Angie Maldonado Rodriguez","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2799503643","display_name":"Columbia University Irving Medical Center","ror":"https://ror.org/01esghr10","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2799503643"]},{"id":"https://openalex.org/I78577930","display_name":"Columbia University","ror":"https://ror.org/00hj8s172","country_code":"US","type":"education","lineage":["https://openalex.org/I78577930"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Angie Maldonado Rodriguez","raw_affiliation_strings":["Department of Neurology, Vagelos College of Physicians and Surgeons, Columbia University, New York, NY 10032, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurology, Vagelos College of Physicians and Surgeons, Columbia University, New York, NY 10032, USA","institution_ids":["https://openalex.org/I2799503643","https://openalex.org/I78577930"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5152129558","display_name":"Richard Pan","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2799503643","display_name":"Columbia University Irving Medical Center","ror":"https://ror.org/01esghr10","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2799503643"]},{"id":"https://openalex.org/I78577930","display_name":"Columbia University","ror":"https://ror.org/00hj8s172","country_code":"US","type":"education","lineage":["https://openalex.org/I78577930"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Richard Pan","raw_affiliation_strings":["Department of Physiology and Cellular Biophysics, Vagelos College of Physicians and Surgeons, Columbia University Medical Center, Columbia University, New York, NY 10032, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Physiology and Cellular Biophysics, Vagelos College of Physicians and Surgeons, Columbia University Medical Center, Columbia University, New York, NY 10032, USA","institution_ids":["https://openalex.org/I2799503643","https://openalex.org/I78577930"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5059059038","display_name":"Ruizhi Wang","orcid":"https://orcid.org/0009-0008-8976-8230","observed_orcids":["https://orcid.org/0009-0008-8976-8230"]},"institutions":[{"id":"https://openalex.org/I2799503643","display_name":"Columbia University Irving Medical Center","ror":"https://ror.org/01esghr10","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2799503643"]},{"id":"https://openalex.org/I78577930","display_name":"Columbia University","ror":"https://ror.org/00hj8s172","country_code":"US","type":"education","lineage":["https://openalex.org/I78577930"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Ruizhi Wang","raw_affiliation_strings":["Department of Neurology, Vagelos College of Physicians and Surgeons, Columbia University, New York, NY 10032, USA"],"raw_orcid":"https://orcid.org/0009-0008-8976-8230","affiliations":[{"raw_affiliation_string":"Department of Neurology, Vagelos College of Physicians and Surgeons, Columbia University, New York, NY 10032, USA","institution_ids":["https://openalex.org/I2799503643","https://openalex.org/I78577930"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5078816337","display_name":"Michelle Jin","orcid":"https://orcid.org/0000-0002-8696-1958","observed_orcids":["https://orcid.org/0000-0002-8696-1958"]},"institutions":[{"id":"https://openalex.org/I2799503643","display_name":"Columbia University Irving Medical Center","ror":"https://ror.org/01esghr10","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2799503643"]},{"id":"https://openalex.org/I78577930","display_name":"Columbia University","ror":"https://ror.org/00hj8s172","country_code":"US","type":"education","lineage":["https://openalex.org/I78577930"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Michelle Jin","raw_affiliation_strings":["Department of Neuroscience, Vagelos College of Physicians and Surgeons, Columbia University Medical Center, Columbia University, New York, NY 10032, USA; Department of Psychiatry, Vagelos College of Physicians and Surgeons, Columbia University, New York, NY 10032, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neuroscience, Vagelos College of Physicians and Surgeons, Columbia University Medical Center, Columbia University, New York, NY 10032, USA; Department of Psychiatry, Vagelos College of Physicians and Surgeons, Columbia University, New York, NY 10032, USA","institution_ids":["https://openalex.org/I2799503643","https://openalex.org/I78577930"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5068425091","display_name":"\u5468\u8fde\u8273","orcid":"https://orcid.org/0009-0001-9085-9171","observed_orcids":["https://orcid.org/0009-0001-9085-9171"]},"institutions":[{"id":"https://openalex.org/I2799503643","display_name":"Columbia University Irving Medical Center","ror":"https://ror.org/01esghr10","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2799503643"]},{"id":"https://openalex.org/I78577930","display_name":"Columbia University","ror":"https://ror.org/00hj8s172","country_code":"US","type":"education","lineage":["https://openalex.org/I78577930"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Lianyan Zhou","raw_affiliation_strings":["Department of Neurology, Vagelos College of Physicians and Surgeons, Columbia University, New York, NY 10032, USA"],"raw_orcid":"https://orcid.org/0009-0001-9085-9171","affiliations":[{"raw_affiliation_string":"Department of Neurology, Vagelos College of Physicians and Surgeons, Columbia University, New York, NY 10032, USA","institution_ids":["https://openalex.org/I2799503643","https://openalex.org/I78577930"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5160043476","display_name":"Kehan Yi","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2799503643","display_name":"Columbia University Irving Medical Center","ror":"https://ror.org/01esghr10","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2799503643"]},{"id":"https://openalex.org/I78577930","display_name":"Columbia University","ror":"https://ror.org/00hj8s172","country_code":"US","type":"education","lineage":["https://openalex.org/I78577930"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Kehan Yi","raw_affiliation_strings":["Department of Physiology and Cellular Biophysics, Vagelos College of Physicians and Surgeons, Columbia University Medical Center, Columbia University, New York, NY 10032, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Physiology and Cellular Biophysics, Vagelos College of Physicians and Surgeons, Columbia University Medical Center, Columbia University, New York, NY 10032, USA","institution_ids":["https://openalex.org/I2799503643","https://openalex.org/I78577930"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5160057545","display_name":"Hanqing Liu","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Hanqing Liu","raw_affiliation_strings":["Department of Neurobiology, Harvard Medical School, Boston, MA 02115, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurobiology, Harvard Medical School, Boston, MA 02115, USA","institution_ids":["https://openalex.org/I136199984"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5143715445","display_name":"Wanding Zhou","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1335321130","display_name":"Children's Hospital of Philadelphia","ror":"https://ror.org/01z7r7q48","country_code":"US","type":"funder","lineage":["https://openalex.org/I1335321130"]},{"id":"https://openalex.org/I79576946","display_name":"University of Pennsylvania","ror":"https://ror.org/00b30xv10","country_code":"US","type":"education","lineage":["https://openalex.org/I79576946"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Wanding Zhou","raw_affiliation_strings":["Center for Computational and Genomic Medicine, The Children's Hospital of Philadelphia, Philadelphia, PA 19104, USA; Department of Pathology and Laboratory Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Computational and Genomic Medicine, The Children's Hospital of Philadelphia, Philadelphia, PA 19104, USA; Department of Pathology and Laboratory Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA","institution_ids":["https://openalex.org/I1335321130","https://openalex.org/I79576946"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5087665557","display_name":"Yueqing Peng","orcid":"https://orcid.org/0000-0002-3488-0670","observed_orcids":["https://orcid.org/0000-0002-3488-0670"]},"institutions":[{"id":"https://openalex.org/I2799503643","display_name":"Columbia University Irving Medical Center","ror":"https://ror.org/01esghr10","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2799503643"]},{"id":"https://openalex.org/I78577930","display_name":"Columbia University","ror":"https://ror.org/00hj8s172","country_code":"US","type":"education","lineage":["https://openalex.org/I78577930"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Yueqing Peng","raw_affiliation_strings":["Department of Neurology, Vagelos College of Physicians and Surgeons, Columbia University, New York, NY 10032, USA; Department of Pathology and Cell Biology, Vagelos College of Physicians and Surgeons, Columbia University Medical Center, Columbia University, New York, NY 10032, USA. Electronic address: yp2249@cumc.columbia.edu"],"raw_orcid":"https://orcid.org/0000-0002-3488-0670","affiliations":[{"raw_affiliation_string":"Department of Neurology, Vagelos College of Physicians and Surgeons, Columbia University, New York, NY 10032, USA; Department of Pathology and Cell Biology, Vagelos College of Physicians and Surgeons, Columbia University Medical Center, Columbia University, New York, NY 10032, USA. Electronic address: yp2249@cumc.columbia.edu","institution_ids":["https://openalex.org/I2799503643","https://openalex.org/I78577930"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5071487394","display_name":"X. Shawn Liu","orcid":"https://orcid.org/0000-0002-2799-2519","observed_orcids":["https://orcid.org/0000-0002-2799-2519"]},"institutions":[{"id":"https://openalex.org/I2799503643","display_name":"Columbia University Irving Medical Center","ror":"https://ror.org/01esghr10","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2799503643"]},{"id":"https://openalex.org/I78577930","display_name":"Columbia University","ror":"https://ror.org/00hj8s172","country_code":"US","type":"education","lineage":["https://openalex.org/I78577930"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"X. Shawn Liu","raw_affiliation_strings":["Department of Physiology and Cellular Biophysics, Vagelos College of Physicians and Surgeons, Columbia University Medical Center, Columbia University, New York, NY 10032, USA. Electronic address: sl4738@cumc.columbia.edu"],"raw_orcid":"https://orcid.org/0000-0002-2799-2519","affiliations":[{"raw_affiliation_string":"Department of Physiology and Cellular Biophysics, Vagelos College of Physicians and Surgeons, Columbia University Medical Center, Columbia University, New York, NY 10032, USA. Electronic address: sl4738@cumc.columbia.edu","institution_ids":["https://openalex.org/I2799503643","https://openalex.org/I78577930"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":6,"corresponding_author_ids":["https://openalex.org/A5071487394","https://openalex.org/A5087665557"],"corresponding_institution_ids":["https://openalex.org/I2799503643","https://openalex.org/I78577930"],"apc_list":{"value":5620,"currency":"USD","value_usd":5620},"apc_paid":{"value":5620,"currency":"USD","value_usd":5620},"fwci":0.0,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":{"value":0.80307524,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"45","issue":"11","first_page":"118190","last_page":"118190"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10448","display_name":"Memory and Neural Mechanisms","score":0.9628999829292297,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10448","display_name":"Memory and Neural Mechanisms","score":0.9628999829292297,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10985","display_name":"Sleep and Wakefulness Research","score":0.030799999833106995,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10269","display_name":"Epigenetics and DNA Methylation","score":0.0027000000700354576,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/sleep-dependent-memory-consolidation","display_name":"sleep-dependent memory consolidation","score":0.9049999713897705},{"id":"https://openalex.org/keywords/dna-methylation","display_name":"DNA methylation","score":0.9810000061988831},{"id":"https://openalex.org/keywords/epigenetic-remodeling","display_name":"epigenetic remodeling","score":0.9039999842643738},{"id":"https://openalex.org/keywords/basolateral-amygdala","display_name":"basolateral amygdala","score":0.8970000147819519},{"id":"https://openalex.org/keywords/fear-memory","display_name":"fear memory","score":0.7630000114440918},{"id":"https://openalex.org/keywords/memory-reconsolidation","display_name":"memory reconsolidation","score":0.6990000009536743}],"concepts":[{"id":"https://openalex.org/C190727270","wikidata":"https://www.wikidata.org/wiki/Q874745","display_name":"DNA methylation","level":4,"score":0.6585000157356262},{"id":"https://openalex.org/C28093023","wikidata":"https://www.wikidata.org/wiki/Q175168","display_name":"Engram","level":2,"score":0.589900016784668},{"id":"https://openalex.org/C2780451725","wikidata":"https://www.wikidata.org/wiki/Q4867818","display_name":"Basolateral amygdala","level":3,"score":0.5825999975204468},{"id":"https://openalex.org/C2779144063","wikidata":"https://www.wikidata.org/wiki/Q338924","display_name":"Amygdala","level":2,"score":0.5353999733924866},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.5012000203132629},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.4659000039100647},{"id":"https://openalex.org/C41091548","wikidata":"https://www.wikidata.org/wiki/Q26939","display_name":"Epigenetics","level":3,"score":0.46399998664855957},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.43070000410079956},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.41830000281333923},{"id":"https://openalex.org/C2778901553","wikidata":"https://www.wikidata.org/wiki/Q238535","display_name":"5-Hydroxymethylcytosine","level":5,"score":0.40470001101493835},{"id":"https://openalex.org/C552990157","wikidata":"https://www.wikidata.org/wiki/Q7430","display_name":"DNA","level":2,"score":0.3968000113964081},{"id":"https://openalex.org/C33288867","wikidata":"https://www.wikidata.org/wiki/Q518328","display_name":"Methylation","level":3,"score":0.37209999561309814},{"id":"https://openalex.org/C150194340","wikidata":"https://www.wikidata.org/wiki/Q26972","display_name":"Gene expression","level":3,"score":0.3075000047683716},{"id":"https://openalex.org/C50738837","wikidata":"https://www.wikidata.org/wiki/Q781492","display_name":"Optogenetics","level":2,"score":0.2786000072956085},{"id":"https://openalex.org/C162317418","wikidata":"https://www.wikidata.org/wiki/Q252857","display_name":"Transcriptome","level":4,"score":0.2761000096797943},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.2612000107765198},{"id":"https://openalex.org/C179463898","wikidata":"https://www.wikidata.org/wiki/Q10273301","display_name":"Epigenesis","level":5,"score":0.2578999996185303},{"id":"https://openalex.org/C2777361361","wikidata":"https://www.wikidata.org/wiki/Q1112585","display_name":"Polarity (international relations)","level":3,"score":0.25609999895095825}],"mesh":[],"locations_count":3,"locations":[{"id":"doi:10.1016/j.celrep.2026.118190","doi":"https://doi.org/10.1016/j.celrep.2026.118190","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.celrep.2026.118190","pdf_url":"https://www.cell.com/cell-reports/pdf/S2211-1247(26)01269-6.pdf","source":{"id":"https://openalex.org/S169236886","display_name":"Cell Reports","issn_l":"2211-1247","issn":["2211-1247","2639-1856"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-b","doyens","jufo-3","ki-jl-2","medline","norway-2","oarl","poland-200","vabb-shw"],"host_organization":"https://openalex.org/P4310315673","host_organization_name":"Cell Press","host_organization_lineage":["https://openalex.org/P4310315673","https://openalex.org/P4310320990"],"host_organization_lineage_names":["Cell Press","Elsevier BV"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cell Reports","raw_type":"journal-article"},{"id":"pmid:42949914","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/42949914","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cell reports","raw_type":"Journal Article"},{"id":"pmh:oai:doaj.org/article:ca16e2554ac144c2a9c59d5c2a5ba120","doi":null,"is_oa":false,"landing_page_url":"https://doaj.org/article/ca16e2554ac144c2a9c59d5c2a5ba120","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Cell Reports, Vol 45, Iss 11, Pp 118190- (2026)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.1016/j.celrep.2026.118190","doi":"https://doi.org/10.1016/j.celrep.2026.118190","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.celrep.2026.118190","pdf_url":"https://www.cell.com/cell-reports/pdf/S2211-1247(26)01269-6.pdf","source":{"id":"https://openalex.org/S169236886","display_name":"Cell Reports","issn_l":"2211-1247","issn":["2211-1247","2639-1856"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-b","doyens","jufo-3","ki-jl-2","medline","norway-2","oarl","poland-200","vabb-shw"],"host_organization":"https://openalex.org/P4310315673","host_organization_name":"Cell Press","host_organization_lineage":["https://openalex.org/P4310315673","https://openalex.org/P4310320990"],"host_organization_lineage_names":["Cell Press","Elsevier BV"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cell Reports","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.504800021648407,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320309170","display_name":"Florida State University","ror":"https://ror.org/05g3dte14"},{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337346","display_name":"National Institute of Mental Health","ror":"https://ror.org/04xeg9z08"},{"id":"https://openalex.org/F4320337359","display_name":"National Institute of Neurological Disorders and Stroke","ror":"https://ror.org/01s5ya894"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W7224126359.pdf","grobid_xml":"https://content.openalex.org/works/W7224126359.grobid-xml"},"referenced_works_count":91,"referenced_works":["https://openalex.org/W1576464279","https://openalex.org/W1920095995","https://openalex.org/W1971396436","https://openalex.org/W1979526394","https://openalex.org/W1985534367","https://openalex.org/W1985995915","https://openalex.org/W2001484935","https://openalex.org/W2008060564","https://openalex.org/W2009614729","https://openalex.org/W2018304597","https://openalex.org/W2018419725","https://openalex.org/W2019252920","https://openalex.org/W2031379951","https://openalex.org/W2038640115","https://openalex.org/W2047148152","https://openalex.org/W2051483319","https://openalex.org/W2064756496","https://openalex.org/W2076312647","https://openalex.org/W2076327464","https://openalex.org/W2083750191","https://openalex.org/W2085974955","https://openalex.org/W2094060127","https://openalex.org/W2102656701","https://openalex.org/W2104846922","https://openalex.org/W2110659025","https://openalex.org/W2111085588","https://openalex.org/W2115818350","https://openalex.org/W2122682406","https://openalex.org/W2139693494","https://openalex.org/W2141674392","https://openalex.org/W2146070554","https://openalex.org/W2152642144","https://openalex.org/W2155505956","https://openalex.org/W2159887581","https://openalex.org/W2162596587","https://openalex.org/W2168645178","https://openalex.org/W2170356111","https://openalex.org/W2171952745","https://openalex.org/W2194751123","https://openalex.org/W2199911847","https://openalex.org/W2262614321","https://openalex.org/W2345356016","https://openalex.org/W2408031231","https://openalex.org/W2488937931","https://openalex.org/W2510223785","https://openalex.org/W2514732099","https://openalex.org/W2521023622","https://openalex.org/W2534475745","https://openalex.org/W2584305758","https://openalex.org/W2604790384","https://openalex.org/W2604988916","https://openalex.org/W2750304043","https://openalex.org/W2761133874","https://openalex.org/W2766704091","https://openalex.org/W2789352630","https://openalex.org/W2800392236","https://openalex.org/W2817838603","https://openalex.org/W2889326414","https://openalex.org/W2897249806","https://openalex.org/W2903944365","https://openalex.org/W2906904130","https://openalex.org/W2909810226","https://openalex.org/W2914830318","https://openalex.org/W2949177718","https://openalex.org/W2953204260","https://openalex.org/W2975634117","https://openalex.org/W2984472267","https://openalex.org/W3003892910","https://openalex.org/W3032372703","https://openalex.org/W3036458710","https://openalex.org/W3093167159","https://openalex.org/W3171613899","https://openalex.org/W3196897371","https://openalex.org/W3200149349","https://openalex.org/W3202606175","https://openalex.org/W3203959602","https://openalex.org/W4224319396","https://openalex.org/W4323320159","https://openalex.org/W4366606050","https://openalex.org/W4385638791","https://openalex.org/W4385728766","https://openalex.org/W4387965083","https://openalex.org/W4392908375","https://openalex.org/W4395447607","https://openalex.org/W4400974527","https://openalex.org/W4401487945","https://openalex.org/W4404395587","https://openalex.org/W4406385607","https://openalex.org/W4407151069","https://openalex.org/W7097355968","https://openalex.org/W7135293462"],"related_works":["https://openalex.org/W4414559933","https://openalex.org/W2735917749","https://openalex.org/W7008742965","https://openalex.org/W4378610482","https://openalex.org/W2974852011","https://openalex.org/W806808397","https://openalex.org/W2057869525","https://openalex.org/W2049417128","https://openalex.org/W2966982187","https://openalex.org/W2777781671"],"abstract_inverted_index":{"How":[0],"sleep":[1,45,80,93],"consolidates":[2],"fear":[3,39,115,137],"memories":[4],"at":[5],"the":[6,22,33,75,99,113],"molecular":[7,110],"level":[8],"within":[9],"individual":[10],"engram":[11,28,59,100,116],"neurons":[12],"is":[13],"unknown.":[14],"Using":[15],"activity-dependent":[16],"tagging":[17],"and":[18,25,29,42,52,87,117,123,128],"sequencing,":[19],"we":[20,106],"profiled":[21],"DNA":[23,54],"methylome":[24,101],"transcriptome":[26,104],"of":[27,74,112],"non-engram":[30],"nuclei":[31],"from":[32],"basolateral":[34],"amygdala":[35],"(BLA)":[36],"after":[37],"contextual":[38],"conditioning":[40],"with":[41,61,102],"without":[43],"post-learning":[44],"deprivation.":[46],"Fear":[47],"learning":[48],"induces":[49],"coordinated":[50],"CpG":[51],"CpH":[53,68],"methylation":[55,69,85,125],"remodeling":[56],"specifically":[57],"in":[58],"neurons,":[60],"each":[62],"showing":[63],"unique":[64],"temporal":[65],"dynamics,":[66],"revealing":[67],"as":[70,120],"a":[71,108,121],"separate":[72],"component":[73],"engram's":[76],"epigenetic":[77,96,147],"signature.":[78],"Interestingly,":[79],"deprivation":[81],"partially":[82],"reverses":[83],"learning-induced":[84],"changes":[86],"impairs":[88],"memory":[89,138],"recall,":[90],"indicating":[91],"that":[92],"supports":[94],"engram-specific":[95,129],"consolidation.":[97],"Integrating":[98],"single-cell":[103],"profiling,":[105],"construct":[107],"multi-omic":[109],"atlas":[111],"BLA":[114],"identify":[118,144],"Mid1":[119,130],"learning-":[122],"sleep-regulated":[124],"target.":[126],"BLA-wide":[127],"knockdown":[131],"establishes":[132],"its":[133],"functional":[134],"requirement":[135],"for":[136],"consolidation,":[139],"providing":[140],"an":[141],"approach":[142],"to":[143],"behaviorally":[145],"relevant":[146],"targets.":[148]},"counts_by_year":[],"updated_date":"2026-11-06T12:05:46.655746","created_date":"2026-10-29T00:00:00"}
