{"id":"https://openalex.org/W7224104233","doi":"https://doi.org/10.1155/cjgh/1261185","title":"Predicting Liver Stiffness Approximately 12 Months Ahead Using Serial Transient Elastography","display_name":"Predicting Liver Stiffness Approximately 12 Months Ahead Using Serial Transient Elastography","publication_year":2026,"publication_date":"2026-01-01","ids":{"openalex":"https://openalex.org/W7224104233","doi":"https://doi.org/10.1155/cjgh/1261185","pmid":"https://pubmed.ncbi.nlm.nih.gov/42947406","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/13714349"},"language":"en","primary_location":{"id":"doi:10.1155/cjgh/1261185","doi":"https://doi.org/10.1155/cjgh/1261185","is_oa":true,"landing_page_url":"https://doi.org/10.1155/cjgh/1261185","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1155/cjgh/1261185","source":{"id":"https://openalex.org/S22732266","display_name":"Canadian Journal of Gastroenterology and Hepatology","issn_l":"2291-2789","issn":["2291-2789","2291-2797"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","doyens","medline","norway-1","poland-70","russia-white-list-2"],"host_organization":"https://openalex.org/P4310313016","host_organization_name":"Pulsus Group","host_organization_lineage":["https://openalex.org/P4310313016","https://openalex.org/P4310320466"],"host_organization_lineage_names":["Pulsus Group","OMICS Publishing Group"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Canadian Journal of Gastroenterology and Hepatology","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1155/cjgh/1261185","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5160042459","display_name":"Ming Lei","orcid":"https://orcid.org/0009-0004-6130-7759","observed_orcids":["https://orcid.org/0009-0004-6130-7759"]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Ming Lei","raw_affiliation_strings":["Department of Hemodialysis Dalian Public Health Clinical Center  No. 269, Gui Bai Road, Lu Gang, Ganjingzi District Dalian Liaoning China"],"raw_orcid":"https://orcid.org/0009-0004-6130-7759","affiliations":[{"raw_affiliation_string":"Department of Hemodialysis Dalian Public Health Clinical Center  No. 269, Gui Bai Road, Lu Gang, Ganjingzi District Dalian Liaoning China","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5002377989","display_name":"Shoukang Zou","orcid":"https://orcid.org/0009-0002-7667-9016","observed_orcids":["https://orcid.org/0009-0002-7667-9016"]},"institutions":[{"id":"https://openalex.org/I4210096200","display_name":"Fourth People's Hospital of Sichuan Province","ror":"https://ror.org/00vva8g89","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210096200"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Shoukang Zou","raw_affiliation_strings":["Unit 4-Department of Geriatric Medicine The Fourth People\u2019s Hospital of Chengdu  No.8 Huli-West First-Alley, Jinniu District Chengdu Sichuan China"],"raw_orcid":"https://orcid.org/0009-0002-7667-9016","affiliations":[{"raw_affiliation_string":"Unit 4-Department of Geriatric Medicine The Fourth People\u2019s Hospital of Chengdu  No.8 Huli-West First-Alley, Jinniu District Chengdu Sichuan China","institution_ids":["https://openalex.org/I4210096200"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5160018781","display_name":"Qing Liu","orcid":"https://orcid.org/0009-0003-5229-1903","observed_orcids":["https://orcid.org/0009-0003-5229-1903"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Qing Liu","raw_affiliation_strings":["Department of Laboratory Medicine Liaoning Electric Power Central Hospital.  No. 2, Wanghu Road, Heping District Shenyang Liaoning China"],"raw_orcid":"https://orcid.org/0009-0003-5229-1903","affiliations":[{"raw_affiliation_string":"Department of Laboratory Medicine Liaoning Electric Power Central Hospital.  No. 2, Wanghu Road, Heping District Shenyang Liaoning China","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5160027893","display_name":"Yangling Li","orcid":"https://orcid.org/0009-0007-5691-8071","observed_orcids":["https://orcid.org/0009-0007-5691-8071"]},"institutions":[{"id":"https://openalex.org/I4210089761","display_name":"West China Hospital of Sichuan University","ror":"https://ror.org/007mrxy13","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210089761"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yangling Li","raw_affiliation_strings":["Department of Gastroenterology West China Hospital of Sichuan University  No. 37, Guoxue Lane, Wuhou District Chengdu Sichuan China  wchscu.cn"],"raw_orcid":"https://orcid.org/0009-0007-5691-8071","affiliations":[{"raw_affiliation_string":"Department of Gastroenterology West China Hospital of Sichuan University  No. 37, Guoxue Lane, Wuhou District Chengdu Sichuan China  wchscu.cn","institution_ids":["https://openalex.org/I4210089761"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5160059682","display_name":"Jing Han","orcid":"https://orcid.org/0009-0000-5028-2489","observed_orcids":["https://orcid.org/0009-0000-5028-2489"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Jing Han","raw_affiliation_strings":["Department of Hemodialysis Dalian Public Health Clinical Center  No. 269, Gui Bai Road, Lu Gang, Ganjingzi District Dalian Liaoning China"],"raw_orcid":"https://orcid.org/0009-0000-5028-2489","affiliations":[{"raw_affiliation_string":"Department of Hemodialysis Dalian Public Health Clinical Center  No. 269, Gui Bai Road, Lu Gang, Ganjingzi District Dalian Liaoning China","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5123656679","display_name":"Yungang Zhang","orcid":"https://orcid.org/0000-0001-8467-5520","observed_orcids":["https://orcid.org/0000-0001-8467-5520","https://orcid.org/0009-0000-0106-416X"]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Yungang Zhang","raw_affiliation_strings":["Department of Hemodialysis Dalian Public Health Clinical Center  No. 269, Gui Bai Road, Lu Gang, Ganjingzi District Dalian Liaoning China"],"raw_orcid":"https://orcid.org/0009-0000-0106-416X","affiliations":[{"raw_affiliation_string":"Department of Hemodialysis Dalian Public Health Clinical Center  No. 269, Gui Bai Road, Lu Gang, Ganjingzi District Dalian Liaoning China","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5014803780","display_name":"Chunwen Pu","orcid":"https://orcid.org/0000-0001-6442-3393","observed_orcids":["https://orcid.org/0000-0001-6442-3393","https://orcid.org/0009-0007-9150-0543"]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Chunwen Pu","raw_affiliation_strings":["Biobank for Biological Samples and Data Dalian Public Health Clinical Center  No. 269, Gui Bai Road, Lu Gang, Ganjingzi District Dalian Liaoning China"],"raw_orcid":"https://orcid.org/0009-0007-9150-0543","affiliations":[{"raw_affiliation_string":"Biobank for Biological Samples and Data Dalian Public Health Clinical Center  No. 269, Gui Bai Road, Lu Gang, Ganjingzi District Dalian Liaoning China","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5014803780","https://openalex.org/A5123656679","https://openalex.org/A5160042459"],"corresponding_institution_ids":[],"apc_list":{"value":2830,"currency":"USD","value_usd":2830},"apc_paid":{"value":2830,"currency":"USD","value_usd":2830},"fwci":0.0,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":{"value":0.79786007,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"2026","issue":"1","first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10351","display_name":"Liver Disease Diagnosis and Treatment","score":0.9550999999046326,"subfield":{"id":"https://openalex.org/subfields/2721","display_name":"Hepatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10351","display_name":"Liver Disease Diagnosis and Treatment","score":0.9550999999046326,"subfield":{"id":"https://openalex.org/subfields/2721","display_name":"Hepatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10727","display_name":"Ultrasound Imaging and Elastography","score":0.02280000038444996,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10337","display_name":"Liver Disease and Transplantation","score":0.0020000000949949026,"subfield":{"id":"https://openalex.org/subfields/2721","display_name":"Hepatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/liver-stiffness-measurement","display_name":"liver stiffness measurement","score":0.9210000038146973},{"id":"https://openalex.org/keywords/transient-elastography","display_name":"transient elastography","score":0.9539999961853027},{"id":"https://openalex.org/keywords/longitudinal-prediction","display_name":"longitudinal prediction","score":0.5640000104904175},{"id":"https://openalex.org/keywords/chronic-liver-disease","display_name":"chronic liver disease","score":0.8859999775886536},{"id":"https://openalex.org/keywords/fibrosis-progression","display_name":"fibrosis progression","score":0.7730000019073486},{"id":"https://openalex.org/keywords/random-forest","display_name":"random forest","score":0.7110000252723694},{"id":"https://openalex.org/keywords/clinical-indicators","display_name":"clinical indicators","score":0.42100000381469727},{"id":"https://openalex.org/keywords/model-calibration","display_name":"model calibration","score":0.48399999737739563}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.6671000123023987},{"id":"https://openalex.org/C44249647","wikidata":"https://www.wikidata.org/wiki/Q208498","display_name":"Confidence interval","level":2,"score":0.6496999859809875},{"id":"https://openalex.org/C165838908","wikidata":"https://www.wikidata.org/wiki/Q736777","display_name":"Calibration","level":2,"score":0.5799000263214111},{"id":"https://openalex.org/C2989005","wikidata":"https://www.wikidata.org/wiki/Q214963","display_name":"Nuclear medicine","level":1,"score":0.517799973487854},{"id":"https://openalex.org/C2779372316","wikidata":"https://www.wikidata.org/wiki/Q569057","display_name":"Stiffness","level":2,"score":0.4991999864578247},{"id":"https://openalex.org/C2780826214","wikidata":"https://www.wikidata.org/wiki/Q1324974","display_name":"Transient elastography","level":4,"score":0.4641999900341034},{"id":"https://openalex.org/C207609745","wikidata":"https://www.wikidata.org/wiki/Q4944086","display_name":"Bootstrapping (finance)","level":2,"score":0.435699999332428},{"id":"https://openalex.org/C2779466056","wikidata":"https://www.wikidata.org/wiki/Q107630651","display_name":"Time point","level":2,"score":0.3693999946117401},{"id":"https://openalex.org/C73782692","wikidata":"https://www.wikidata.org/wiki/Q196372","display_name":"Random error","level":2,"score":0.3537999987602234},{"id":"https://openalex.org/C105054674","wikidata":"https://www.wikidata.org/wiki/Q3707381","display_name":"Mean difference","level":3,"score":0.3490000069141388},{"id":"https://openalex.org/C58489278","wikidata":"https://www.wikidata.org/wiki/Q1172284","display_name":"Data set","level":2,"score":0.336899995803833},{"id":"https://openalex.org/C2986012078","wikidata":"https://www.wikidata.org/wiki/Q210868","display_name":"Sampling interval","level":2,"score":0.321399986743927},{"id":"https://openalex.org/C3020672099","wikidata":"https://www.wikidata.org/wiki/Q857354","display_name":"Longitudinal data","level":2,"score":0.31349998712539673},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.3077999949455261},{"id":"https://openalex.org/C136229726","wikidata":"https://www.wikidata.org/wiki/Q327092","display_name":"Biomedical engineering","level":1,"score":0.3059000074863434},{"id":"https://openalex.org/C2777690781","wikidata":"https://www.wikidata.org/wiki/Q1324974","display_name":"Elastography","level":3,"score":0.30250000953674316},{"id":"https://openalex.org/C169903167","wikidata":"https://www.wikidata.org/wiki/Q3985153","display_name":"Test set","level":2,"score":0.3003999888896942},{"id":"https://openalex.org/C2777895361","wikidata":"https://www.wikidata.org/wiki/Q1758614","display_name":"Longitudinal study","level":2,"score":0.296099990606308},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.28369998931884766},{"id":"https://openalex.org/C105795698","wikidata":"https://www.wikidata.org/wiki/Q12483","display_name":"Statistics","level":1,"score":0.2761000096797943},{"id":"https://openalex.org/C2779974597","wikidata":"https://www.wikidata.org/wiki/Q28448986","display_name":"Clinical Practice","level":2,"score":0.2728999853134155},{"id":"https://openalex.org/C2909095640","wikidata":"https://www.wikidata.org/wiki/Q1324974","display_name":"Ultrasound elastography","level":4,"score":0.2727999985218048},{"id":"https://openalex.org/C535046627","wikidata":"https://www.wikidata.org/wiki/Q30612","display_name":"Clinical trial","level":2,"score":0.2703000009059906},{"id":"https://openalex.org/C198433322","wikidata":"https://www.wikidata.org/wiki/Q3910099","display_name":"Predictive value of tests","level":2,"score":0.26829999685287476},{"id":"https://openalex.org/C18747219","wikidata":"https://www.wikidata.org/wiki/Q620994","display_name":"Standard error","level":2,"score":0.2680000066757202},{"id":"https://openalex.org/C168563851","wikidata":"https://www.wikidata.org/wiki/Q1436668","display_name":"Randomized controlled trial","level":2,"score":0.2671999931335449},{"id":"https://openalex.org/C27181475","wikidata":"https://www.wikidata.org/wiki/Q541014","display_name":"Cross-validation","level":2,"score":0.26429998874664307},{"id":"https://openalex.org/C2992435398","wikidata":"https://www.wikidata.org/wiki/Q6934595","display_name":"Multicenter study","level":3,"score":0.26420000195503235},{"id":"https://openalex.org/C2992444157","wikidata":"https://www.wikidata.org/wiki/Q775079","display_name":"Single point","level":3,"score":0.25029999017715454}],"mesh":[{"descriptor_ui":"D000093743","descriptor_name":"Random Forest","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008099","descriptor_name":"Liver","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":true},{"descriptor_ui":"D008099","descriptor_name":"Liver","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D008103","descriptor_name":"Liver Cirrhosis","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":true},{"descriptor_ui":"D008107","descriptor_name":"Liver Diseases","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":true},{"descriptor_ui":"D008137","descriptor_name":"Longitudinal Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011237","descriptor_name":"Predictive Value of Tests","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012189","descriptor_name":"Retrospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013997","descriptor_name":"Time Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015203","descriptor_name":"Reproducibility of Results","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D054459","descriptor_name":"Elasticity Imaging Techniques","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true}],"locations_count":4,"locations":[{"id":"doi:10.1155/cjgh/1261185","doi":"https://doi.org/10.1155/cjgh/1261185","is_oa":true,"landing_page_url":"https://doi.org/10.1155/cjgh/1261185","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1155/cjgh/1261185","source":{"id":"https://openalex.org/S22732266","display_name":"Canadian Journal of Gastroenterology and Hepatology","issn_l":"2291-2789","issn":["2291-2789","2291-2797"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","doyens","medline","norway-1","poland-70","russia-white-list-2"],"host_organization":"https://openalex.org/P4310313016","host_organization_name":"Pulsus Group","host_organization_lineage":["https://openalex.org/P4310313016","https://openalex.org/P4310320466"],"host_organization_lineage_names":["Pulsus Group","OMICS Publishing Group"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Canadian Journal of Gastroenterology and Hepatology","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:13714349","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC13714349/","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC13714349/pdf/CJGH-2026-1261185.pdf","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Can J Gastroenterol Hepatol","raw_type":"Text"},{"id":"pmid:42947406","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/42947406","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Canadian journal of gastroenterology & hepatology","raw_type":"Journal Article"},{"id":"pmh:oai:doaj.org/article:7241518a0cc94777a23390d82117b51f","doi":null,"is_oa":false,"landing_page_url":"https://doaj.org/article/7241518a0cc94777a23390d82117b51f","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Canadian Journal of Gastroenterology and Hepatology, Vol 2026 (2026)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.1155/cjgh/1261185","doi":"https://doi.org/10.1155/cjgh/1261185","is_oa":true,"landing_page_url":"https://doi.org/10.1155/cjgh/1261185","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1155/cjgh/1261185","source":{"id":"https://openalex.org/S22732266","display_name":"Canadian Journal of Gastroenterology and Hepatology","issn_l":"2291-2789","issn":["2291-2789","2291-2797"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","doyens","medline","norway-1","poland-70","russia-white-list-2"],"host_organization":"https://openalex.org/P4310313016","host_organization_name":"Pulsus Group","host_organization_lineage":["https://openalex.org/P4310313016","https://openalex.org/P4310320466"],"host_organization_lineage_names":["Pulsus Group","OMICS Publishing Group"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Canadian Journal of Gastroenterology and Hepatology","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.9537000060081482}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W7224104233.pdf","grobid_xml":"https://content.openalex.org/works/W7224104233.grobid-xml"},"referenced_works_count":51,"referenced_works":["https://openalex.org/W1678356000","https://openalex.org/W1987971958","https://openalex.org/W1997865776","https://openalex.org/W2027498662","https://openalex.org/W2064387090","https://openalex.org/W2088337379","https://openalex.org/W2093904708","https://openalex.org/W2099184552","https://openalex.org/W2110580470","https://openalex.org/W2112496618","https://openalex.org/W2119910794","https://openalex.org/W2124171243","https://openalex.org/W2128366104","https://openalex.org/W2128596638","https://openalex.org/W2141007997","https://openalex.org/W2162280127","https://openalex.org/W2528274262","https://openalex.org/W2734724639","https://openalex.org/W2767262086","https://openalex.org/W2896476100","https://openalex.org/W2907554860","https://openalex.org/W2911964244","https://openalex.org/W2913997948","https://openalex.org/W2996480032","https://openalex.org/W3003904779","https://openalex.org/W3040545282","https://openalex.org/W3046545849","https://openalex.org/W3094834023","https://openalex.org/W3137152892","https://openalex.org/W3143409077","https://openalex.org/W3154897461","https://openalex.org/W3174905293","https://openalex.org/W3185148315","https://openalex.org/W4200103499","https://openalex.org/W4234698323","https://openalex.org/W4235169531","https://openalex.org/W4285678391","https://openalex.org/W4309306328","https://openalex.org/W4388849564","https://openalex.org/W4391744369","https://openalex.org/W4392856685","https://openalex.org/W4394857110","https://openalex.org/W4396979237","https://openalex.org/W4399125221","https://openalex.org/W4400097826","https://openalex.org/W4401116198","https://openalex.org/W4402199506","https://openalex.org/W4404061115","https://openalex.org/W4407903057","https://openalex.org/W4413866760","https://openalex.org/W7171499370"],"related_works":["https://openalex.org/W4401511668","https://openalex.org/W4308721888","https://openalex.org/W4394873998","https://openalex.org/W2770799053","https://openalex.org/W2324218806","https://openalex.org/W2415738812","https://openalex.org/W2095851283","https://openalex.org/W13771369","https://openalex.org/W1858944688","https://openalex.org/W4328014576"],"abstract_inverted_index":{"Background":[0],"Liver":[1],"stiffness":[2],"measurement":[3,16],"(LSM)":[4],"is":[5,248],"widely":[6],"used":[7],"to":[8,65,215],"assess":[9],"chronic":[10],"liver":[11],"disease,":[12],"but":[13,237],"a":[14,53,84,206],"single":[15],"does":[17],"not":[18,239],"capture":[19],"longitudinal":[20,42,112],"change.":[21],"We":[22],"evaluated":[23],"whether":[24],"serial":[25],"LSMs":[26,51],"and":[27,52,71,94,109,157,177,232],"routine":[28],"clinical":[29,251],"indicators":[30],"could":[31],"predict":[32],"continuous":[33],"LSM":[34,55,63,202,218],"approximately":[35],"12":[36],"months":[37],"later.":[38],"Methods":[39],"This":[40],"retrospective":[41],"study":[43],"included":[44,124],"patients":[45,126],"with":[46,111,205],"at":[47],"least":[48],"two":[49],"historical":[50],"follow\u2010up":[54],"270\u2013450":[56],"days":[57,67],"after":[58],"the":[59,69,75,103,138,164,184,187,199,221,241],"index":[60],"date.":[61],"The":[62,122,225],"closest":[64],"365":[66],"was":[68,106,135,146,154,160,168,174,180],"outcome,":[70],"each":[72],"patient":[73],"contributed":[74],"earliest":[76],"eligible":[77],"task.":[78],"Patients":[79],"were":[80,220],"separated":[81],"chronologically":[82],"into":[83],"train":[85],"set":[86,92,96],"(index":[87],"date":[88],"through":[89],"2022),":[90],"test":[91,139,185],"(2023),":[93],"validation":[95,165,247],"(2024).":[97],"Nested":[98],"expanding":[99],"temporal":[100],"cross\u2010validation":[101],"selected":[102],"model,":[104],"which":[105],"then":[107],"fixed":[108],"compared":[110],"benchmarks.":[113],"Patient\u2010level":[114],"bootstrapping":[115],"provided":[116],"95%":[117],"confidence":[118],"intervals":[119],"(CIs).":[120],"Results":[121],"analysis":[123],"715":[125],"(train,":[127],"434;":[128],"test,":[129],"178;":[130],"validation,":[131],"103).":[132],"Random":[133],"forest":[134],"selected.":[136],"In":[137,163,183],"set,":[140,166,186],"its":[141],"mean":[142],"absolute":[143],"error":[144],"(MAE)":[145],"3.622":[147],"kPa":[148,170,193,213],"(95%":[149],"CI,":[150],"2.828\u20134.769),":[151],"R":[152,172],"2":[153,173],"0.456":[155],"(0.240\u20130.550),":[156],"calibration":[158,178,234],"slope":[159,179],"1.043":[161],"(0.612\u20131.475).":[162],"MAE":[167,190,209],"2.989":[169],"(2.149\u20134.149),":[171],"0.432":[175],"(\u22120.141\u20130.575),":[176],"0.951":[181],"(0.513\u20131.598).":[182],"model":[188,227],"reduced":[189],"by":[191],"8.443":[192],"(4.833\u201312.605)":[194],"versus":[195],"linear\u2010trend":[196],"extrapolation;":[197],"however,":[198],"last":[200,242],"observed":[201,243],"performed":[203],"better,":[204],"paired":[207],"last\u2010observed\u2010LSM\u2010minus\u2010model":[208],"difference":[210],"of":[211],"\u22120.658":[212],"(\u22121.168":[214],"\u22120.187).":[216],"Historical":[217],"summaries":[219],"dominant":[222],"features.":[223],"Conclusions":[224],"locked":[226],"showed":[228],"reproducible":[229],"out\u2010of\u2010time":[230],"performance":[231],"near\u2010ideal":[233],"point":[235],"estimates":[236],"did":[238],"outperform":[240],"LSM.":[244],"Independent":[245],"multicenter":[246],"required":[249],"before":[250],"translation.":[252],"Trial":[253],"Registration:":[254],"ClinicalTrials.gov":[255],"identifier:":[256],"NCT06123858":[257]},"counts_by_year":[],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2026-10-29T00:00:00"}