{"id":"https://openalex.org/W7224097207","doi":"https://doi.org/10.5281/zenodo.23725580","title":"Information Looking for Its Owner in DNA Repair","display_name":"Information Looking for Its Owner in DNA Repair","publication_year":2026,"publication_date":"2026-10-28","ids":{"openalex":"https://openalex.org/W7224097207","doi":"https://doi.org/10.5281/zenodo.23725580"},"language":"en","primary_location":{"id":"doi:10.5281/zenodo.23725580","doi":"https://doi.org/10.5281/zenodo.23725580","is_oa":true,"landing_page_url":"https://doi.org/10.5281/zenodo.23725580","pdf_url":null,"source":{"id":"https://openalex.org/S4306400562","display_name":"Zenodo (CERN European Organization for Nuclear Research)","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I67311998","host_organization_name":"European Organization for Nuclear Research","host_organization_lineage":["https://openalex.org/I67311998"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Preprint"},"volume":null,"type":"preprint","is_traditional":true,"indexed_in":["datacite"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://doi.org/10.5281/zenodo.23725580","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5120952914","display_name":"Erkan Bayar","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Bayar, Erkan","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":["https://openalex.org/A5120952914"],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":1,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10123","display_name":"DNA Repair Mechanisms","score":0.9887999892234802,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10123","display_name":"DNA Repair Mechanisms","score":0.9887999892234802,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10432","display_name":"DNA and Nucleic Acid Chemistry","score":0.002899999963119626,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11520","display_name":"Advanced Thermodynamics and Statistical Mechanics","score":0.000699999975040555,"subfield":{"id":"https://openalex.org/subfields/3109","display_name":"Statistical and Nonlinear Physics"},"field":{"id":"https://openalex.org/fields/31","display_name":"Physics and Astronomy"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/dna-repair","display_name":"DNA repair","score":0.7350000143051147},{"id":"https://openalex.org/keywords/nucleotide-excision-repair","display_name":"nucleotide excision repair","score":0.9559999704360962},{"id":"https://openalex.org/keywords/cyclobutane-pyrimidine-dimers","display_name":"cyclobutane pyrimidine dimers","score":0.9330000281333923},{"id":"https://openalex.org/keywords/uv-damage","display_name":"UV damage","score":0.7099999785423279},{"id":"https://openalex.org/keywords/kinetic-proofreading","display_name":"kinetic proofreading","score":0.7710000276565552},{"id":"https://openalex.org/keywords/repair-kinetics","display_name":"repair kinetics","score":0.31299999356269836}],"concepts":[{"id":"https://openalex.org/C167975912","wikidata":"https://www.wikidata.org/wiki/Q1018722","display_name":"Pyrimidine dimer","level":4,"score":0.6195999979972839},{"id":"https://openalex.org/C177264268","wikidata":"https://www.wikidata.org/wiki/Q1514741","display_name":"Set (abstract data type)","level":2,"score":0.49410000443458557},{"id":"https://openalex.org/C552990157","wikidata":"https://www.wikidata.org/wiki/Q7430","display_name":"DNA","level":2,"score":0.4742000102996826},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.454800009727478},{"id":"https://openalex.org/C134935766","wikidata":"https://www.wikidata.org/wiki/Q210538","display_name":"DNA repair","level":3,"score":0.4438999891281128},{"id":"https://openalex.org/C104451858","wikidata":"https://www.wikidata.org/wiki/Q2714458","display_name":"Nucleotide excision repair","level":4,"score":0.4350000023841858},{"id":"https://openalex.org/C48103436","wikidata":"https://www.wikidata.org/wiki/Q599031","display_name":"State (computer science)","level":2,"score":0.41620001196861267},{"id":"https://openalex.org/C2775924081","wikidata":"https://www.wikidata.org/wiki/Q55608371","display_name":"Control (management)","level":2,"score":0.4050000011920929},{"id":"https://openalex.org/C512185932","wikidata":"https://www.wikidata.org/wiki/Q28745","display_name":"Nucleotide","level":3,"score":0.3837999999523163},{"id":"https://openalex.org/C197077220","wikidata":"https://www.wikidata.org/wiki/Q720988","display_name":"Human genome","level":4,"score":0.37630000710487366},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.3610999882221222},{"id":"https://openalex.org/C141231307","wikidata":"https://www.wikidata.org/wiki/Q7020","display_name":"Genome","level":3,"score":0.34709998965263367},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.3452000021934509},{"id":"https://openalex.org/C2779546866","wikidata":"https://www.wikidata.org/wiki/Q531306","display_name":"Dimer","level":2,"score":0.3296999931335449},{"id":"https://openalex.org/C12554922","wikidata":"https://www.wikidata.org/wiki/Q7100","display_name":"Biophysics","level":1,"score":0.3244999945163727},{"id":"https://openalex.org/C185581394","wikidata":"https://www.wikidata.org/wiki/Q145911","display_name":"Base pair","level":3,"score":0.32339999079704285},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.32249999046325684},{"id":"https://openalex.org/C141353440","wikidata":"https://www.wikidata.org/wiki/Q182221","display_name":"Fuse (electrical)","level":2,"score":0.31949999928474426},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.2750000059604645},{"id":"https://openalex.org/C2780385302","wikidata":"https://www.wikidata.org/wiki/Q367158","display_name":"Protocol (science)","level":3,"score":0.2743000090122223},{"id":"https://openalex.org/C2987116853","wikidata":"https://www.wikidata.org/wiki/Q11391","display_name":"Ultraviolet light","level":2,"score":0.27090001106262207},{"id":"https://openalex.org/C2780377690","wikidata":"https://www.wikidata.org/wiki/Q80232","display_name":"Cyclobutane","level":3,"score":0.26820001006126404},{"id":"https://openalex.org/C2986317502","wikidata":"https://www.wikidata.org/wiki/Q570714","display_name":"Energy metabolism","level":2,"score":0.26820001006126404},{"id":"https://openalex.org/C143425029","wikidata":"https://www.wikidata.org/wiki/Q5205747","display_name":"DNA damage","level":3,"score":0.2678999900817871},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.26089999079704285},{"id":"https://openalex.org/C42058472","wikidata":"https://www.wikidata.org/wiki/Q810214","display_name":"Base (topology)","level":2,"score":0.25870001316070557}],"mesh":[],"locations_count":2,"locations":[{"id":"doi:10.5281/zenodo.23725580","doi":"https://doi.org/10.5281/zenodo.23725580","is_oa":true,"landing_page_url":"https://doi.org/10.5281/zenodo.23725580","pdf_url":null,"source":{"id":"https://openalex.org/S4306400562","display_name":"Zenodo (CERN European Organization for Nuclear Research)","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I67311998","host_organization_name":"European Organization for Nuclear Research","host_organization_lineage":["https://openalex.org/I67311998"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Preprint"},{"id":"doi:10.5281/zenodo.23725581","doi":"https://doi.org/10.5281/zenodo.23725581","is_oa":true,"landing_page_url":"https://doi.org/10.5281/zenodo.23725581","pdf_url":null,"source":{"id":"https://openalex.org/S4306400562","display_name":"Zenodo (CERN European Organization for Nuclear Research)","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I67311998","host_organization_name":"European Organization for Nuclear Research","host_organization_lineage":["https://openalex.org/I67311998"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Preprint"}],"best_oa_location":{"id":"doi:10.5281/zenodo.23725580","doi":"https://doi.org/10.5281/zenodo.23725580","is_oa":true,"landing_page_url":"https://doi.org/10.5281/zenodo.23725580","pdf_url":null,"source":{"id":"https://openalex.org/S4306400562","display_name":"Zenodo (CERN European Organization for Nuclear Research)","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I67311998","host_organization_name":"European Organization for Nuclear Research","host_organization_lineage":["https://openalex.org/I67311998"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Preprint"},"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":2,"referenced_works":["https://openalex.org/W2625176645","https://openalex.org/W7106516671"],"related_works":["https://openalex.org/W1973170344","https://openalex.org/W1603844734","https://openalex.org/W128868113","https://openalex.org/W2134181073","https://openalex.org/W2281395179","https://openalex.org/W4391278168","https://openalex.org/W1836983423","https://openalex.org/W2490540142","https://openalex.org/W2042391520","https://openalex.org/W2068091125"],"abstract_inverted_index":{"Ultraviolet":[0],"light":[1],"writes":[2],"a":[3,12,31,52,58,61,65,84,111,168,173,222,226,267],"mark":[4,18],"into":[5,11],"DNA:":[6],"two":[7],"neighbouring":[8],"pyrimidines":[9],"fuse":[10],"cyclobutane":[13],"pyrimidine":[14],"dimer":[15],"(CPD).":[16],"The":[17,170],"is":[19,100,130,154,293],"information":[20,184],"without":[21],"an":[22],"owner.":[23],"Somewhere":[24],"among":[25],"billions":[26],"of":[27,33,54,70,86,246,270],"intact":[28],"base":[29],"pairs,":[30],"set":[32],"proteins":[34],"has":[35,256],"to":[36,77,151,185],"find":[37,186],"it,":[38,40],"confirm":[39],"cut":[41],"it":[42,76,107,179],"out":[43],"and":[44,74,110,190,207,274,282],"rewrite":[45],"the":[46,68,95,101,105,115,119,131,144,211,214,247],"gap.":[47],"This":[48,284],"application":[49],"note":[50,171,215,285],"borrows":[51],"way":[53],"asking":[55],"questions,":[56],"not":[57,104,142,257,287],"result,":[59],"from":[60],"protocol":[62],"written":[63],"for":[64,183,202],"different":[66],"system,":[67],"freezing":[69],"supercooled":[71],"water":[72],"(doi:10.5281/zenodo.23724281),":[73],"applies":[75],"nucleotide":[78],"excision":[79,133],"repair.":[80],"Three":[81],"things":[82],"transfer:":[83,143],"separation":[85],"five":[87],"roles":[88],"(source,":[89],"carrier,":[90],"processor,":[91],"state":[92,106],"builder,":[93],"meaning-giver);":[94],"idea":[96],"that":[97,113,128,147,164,176],"what":[98,178],"matters":[99],"irreversible":[102,152],"act,":[103],"leaves":[108],"behind;":[109],"control":[112,129],"spends":[114],"same":[116,120,212],"energy":[117],"with":[118,266],"machinery":[121],"but":[122],"produces":[123,194],"no":[124,217],"record.":[125],"In":[126],"repair,":[127],"full":[132],"system":[134],"working":[135],"on":[136,277],"undamaged":[137],"DNA.":[138],"One":[139],"thing":[140],"does":[141,286],"clock":[145,163],"effect":[146],"Time-Gel":[148,289],"Theory":[149],"attaches":[150],"events":[153],"about":[155,244,271],"10^-11":[156],"s":[157],"per":[158],"cell,":[159],"far":[160],"below":[161],"any":[162],"could":[165],"sit":[166],"inside":[167],"cell.":[169],"proposes":[172],"biochemical":[174],"experiment":[175],"measures":[177],"costs,":[180],"in":[181,232,250],"ATP,":[182],"its":[187],"correct":[188],"owner,":[189],"whether":[191],"paying":[192],"less":[193],"more":[195],"wrong":[196],"owners.":[197],"Conventional":[198],"kinetic":[199],"proofreading,":[200],"proposed":[201],"this":[203],"step":[204],"by":[205],"Reardon":[206],"Sancar":[208],"(2003),":[209],"predicts":[210],"outcomes;":[213],"claims":[216],"discrimination.":[218],"It":[219],"then":[220],"takes":[221],"first":[223],"look":[224],"at":[225,260],"public":[227],"CPD":[228],"Damage-seq":[229],"time":[230],"course":[231],"human":[233],"fibroblasts":[234],"(Hu":[235],"et":[236],"al.,":[237],"PNAS":[238],"2017).":[239],"Thirty-six":[240],"hours":[241],"after":[242],"UV,":[243],"17%":[245],"genome":[248],"sits":[249],"100":[251],"kb":[252,273],"bins":[253,263],"whose":[254],"damage":[255],"gone":[258],"down":[259],"all;":[261],"these":[262],"form":[264],"blocks":[265],"mean":[268],"length":[269],"560":[272],"are":[275],"concentrated":[276],"chromosomes":[278],"21,":[279],"X,":[280],"13":[281],"18.":[283],"test":[288],"Theory.":[290],"Every":[291],"claim":[292],"labelled":[294],"(MEASURED,":[295],"OBSERVED,":[296],"MODEL,":[297],"HYPOTHESIS,":[298],"DECISION,":[299],"OPEN,":[300],"INTERPRETATION,":[301],"ANALOGY).":[302]},"counts_by_year":[{"year":2026,"cited_by_count":1}],"updated_date":"2026-10-30T12:39:25.321706","created_date":"2026-10-29T00:00:00"}