{"id":"https://openalex.org/W7224014899","doi":"https://doi.org/10.3390/sci8110317","title":"Paired 3 T and 7 T MP2RAGE Brain Volumetry: Preserved Rank Order, Region-Dependent Offsets, and Exploratory Cross-Field Calibration","display_name":"Paired 3 T and 7 T MP2RAGE Brain Volumetry: Preserved Rank Order, Region-Dependent Offsets, and Exploratory Cross-Field Calibration","publication_year":2026,"publication_date":"2026-10-27","ids":{"openalex":"https://openalex.org/W7224014899","doi":"https://doi.org/10.3390/sci8110317"},"language":"en","primary_location":{"id":"doi:10.3390/sci8110317","doi":"https://doi.org/10.3390/sci8110317","is_oa":true,"landing_page_url":"https://doi.org/10.3390/sci8110317","pdf_url":null,"source":{"id":"https://openalex.org/S4210202795","display_name":"Sci","issn_l":"2413-4155","issn":["2413-4155"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj"],"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Sci","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://doi.org/10.3390/sci8110317","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5015869273","display_name":"Zaheer Abbas","orcid":"https://orcid.org/0000-0002-0650-8388","observed_orcids":["https://orcid.org/0000-0002-0650-8388"]},"institutions":[{"id":"https://openalex.org/I171892758","display_name":"Forschungszentrum J\u00fclich","ror":"https://ror.org/02nv7yv05","country_code":"DE","type":"facility","lineage":["https://openalex.org/I1305996414","https://openalex.org/I171892758"]}],"countries":["DE"],"is_corresponding":true,"raw_author_name":"Zaheer Abbas","raw_affiliation_strings":["Institute of Neuroscience and Medicine 4 (INM-4), Forschungszentrum J\u00fclich, 52425 J\u00fclich, Germany"],"raw_orcid":"https://orcid.org/0000-0002-0650-8388","affiliations":[{"raw_affiliation_string":"Institute of Neuroscience and Medicine 4 (INM-4), Forschungszentrum J\u00fclich, 52425 J\u00fclich, Germany","institution_ids":["https://openalex.org/I171892758"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5148489607","display_name":"Sergo Gegechkori","orcid":"https://orcid.org/0009-0008-7855-2071","observed_orcids":["https://orcid.org/0009-0008-7855-2071"]},"institutions":[{"id":"https://openalex.org/I171892758","display_name":"Forschungszentrum J\u00fclich","ror":"https://ror.org/02nv7yv05","country_code":"DE","type":"facility","lineage":["https://openalex.org/I1305996414","https://openalex.org/I171892758"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Sergo Gegechkori","raw_affiliation_strings":["Institute of Neuroscience and Medicine 4 (INM-4), Forschungszentrum J\u00fclich, 52425 J\u00fclich, Germany"],"raw_orcid":"https://orcid.org/0009-0008-7855-2071","affiliations":[{"raw_affiliation_string":"Institute of Neuroscience and Medicine 4 (INM-4), Forschungszentrum J\u00fclich, 52425 J\u00fclich, Germany","institution_ids":["https://openalex.org/I171892758"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5102764808","display_name":"Faizan Ullah","orcid":"https://orcid.org/0000-0001-6009-6153","observed_orcids":["https://orcid.org/0000-0001-6009-6153"]},"institutions":[{"id":"https://openalex.org/I171892758","display_name":"Forschungszentrum J\u00fclich","ror":"https://ror.org/02nv7yv05","country_code":"DE","type":"facility","lineage":["https://openalex.org/I1305996414","https://openalex.org/I171892758"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Faizan Ullah","raw_affiliation_strings":["Institute of Neuroscience and Medicine 4 (INM-4), Forschungszentrum J\u00fclich, 52425 J\u00fclich, Germany"],"raw_orcid":"https://orcid.org/0000-0001-6009-6153","affiliations":[{"raw_affiliation_string":"Institute of Neuroscience and Medicine 4 (INM-4), Forschungszentrum J\u00fclich, 52425 J\u00fclich, Germany","institution_ids":["https://openalex.org/I171892758"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5071643772","display_name":"Nadim Jon Shah","orcid":"https://orcid.org/0000-0002-8151-6169","observed_orcids":["https://orcid.org/0000-0002-8151-6169"]},"institutions":[{"id":"https://openalex.org/I171892758","display_name":"Forschungszentrum J\u00fclich","ror":"https://ror.org/02nv7yv05","country_code":"DE","type":"facility","lineage":["https://openalex.org/I1305996414","https://openalex.org/I171892758"]},{"id":"https://openalex.org/I4210133912","display_name":"J\u00fclich Aachen Research Alliance","ror":"https://ror.org/02r0e4r58","country_code":"DE","type":"facility","lineage":["https://openalex.org/I1305996414","https://openalex.org/I171892758","https://openalex.org/I4210133912"]},{"id":"https://openalex.org/I887968799","display_name":"RWTH Aachen University","ror":"https://ror.org/04xfq0f34","country_code":"DE","type":"education","lineage":["https://openalex.org/I887968799"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"N. Jon Shah","raw_affiliation_strings":["Department of Neurology, RWTH Aachen University, 52074 Aachen, Germany","Institute of Neuroscience and Medicine 4 (INM-4), Forschungszentrum J\u00fclich, 52425 J\u00fclich, Germany","JARA Institute Molecular Neuroscience and Neuroimaging, 52074 Aachen, Germany"],"raw_orcid":"https://orcid.org/0000-0002-8151-6169","affiliations":[{"raw_affiliation_string":"Department of Neurology, RWTH Aachen University, 52074 Aachen, Germany","institution_ids":["https://openalex.org/I887968799"]},{"raw_affiliation_string":"Institute of Neuroscience and Medicine 4 (INM-4), Forschungszentrum J\u00fclich, 52425 J\u00fclich, Germany","institution_ids":["https://openalex.org/I171892758"]},{"raw_affiliation_string":"JARA Institute Molecular Neuroscience and Neuroimaging, 52074 Aachen, Germany","institution_ids":["https://openalex.org/I4210133912"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5015869273"],"corresponding_institution_ids":["https://openalex.org/I171892758"],"apc_list":{"value":1200,"currency":"CHF","value_usd":1448},"apc_paid":{"value":1200,"currency":"CHF","value_usd":1448},"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.81233069,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"8","issue":"11","first_page":"317","last_page":"317"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10378","display_name":"Advanced MRI Techniques and Applications","score":0.9711999893188477,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10378","display_name":"Advanced MRI Techniques and Applications","score":0.9711999893188477,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10052","display_name":"Medical Image Segmentation Techniques","score":0.0071000000461936,"subfield":{"id":"https://openalex.org/subfields/1707","display_name":"Computer Vision and Pattern Recognition"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11304","display_name":"Advanced Neuroimaging Techniques and Applications","score":0.005900000222027302,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/mp2rage","display_name":"MP2RAGE","score":0.9580000042915344},{"id":"https://openalex.org/keywords/brain-volumetry","display_name":"brain volumetry","score":0.7910000085830688},{"id":"https://openalex.org/keywords/subcortical-structures","display_name":"subcortical structures","score":0.8539999723434448},{"id":"https://openalex.org/keywords/hippocampus","display_name":"hippocampus","score":0.8320000171661377},{"id":"https://openalex.org/keywords/synthseg","display_name":"SynthSeg","score":0.8629999756813049}],"concepts":[{"id":"https://openalex.org/C206041023","wikidata":"https://www.wikidata.org/wiki/Q1751970","display_name":"Wilcoxon signed-rank test","level":3,"score":0.7813000082969666},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.642799973487854},{"id":"https://openalex.org/C105795698","wikidata":"https://www.wikidata.org/wiki/Q12483","display_name":"Statistics","level":1,"score":0.5673999786376953},{"id":"https://openalex.org/C2989005","wikidata":"https://www.wikidata.org/wiki/Q214963","display_name":"Nuclear medicine","level":1,"score":0.5580999851226807},{"id":"https://openalex.org/C165838908","wikidata":"https://www.wikidata.org/wiki/Q736777","display_name":"Calibration","level":2,"score":0.5475000143051147},{"id":"https://openalex.org/C105054674","wikidata":"https://www.wikidata.org/wiki/Q3707381","display_name":"Mean difference","level":3,"score":0.42669999599456787},{"id":"https://openalex.org/C70437156","wikidata":"https://www.wikidata.org/wiki/Q7228652","display_name":"Pooling","level":2,"score":0.4185999929904938},{"id":"https://openalex.org/C159744936","wikidata":"https://www.wikidata.org/wiki/Q1126730","display_name":"Spearman's rank correlation coefficient","level":2,"score":0.38609999418258667},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.37459999322891235},{"id":"https://openalex.org/C164226766","wikidata":"https://www.wikidata.org/wiki/Q7293202","display_name":"Rank (graph theory)","level":2,"score":0.35690000653266907},{"id":"https://openalex.org/C2778724333","wikidata":"https://www.wikidata.org/wiki/Q14401","display_name":"Kappa","level":2,"score":0.3488999903202057},{"id":"https://openalex.org/C106347477","wikidata":"https://www.wikidata.org/wiki/Q5384228","display_name":"Equating","level":3,"score":0.2865000069141388},{"id":"https://openalex.org/C175291020","wikidata":"https://www.wikidata.org/wiki/Q1156822","display_name":"Offset (computer science)","level":2,"score":0.27889999747276306},{"id":"https://openalex.org/C3018260909","wikidata":"https://www.wikidata.org/wiki/Q1322871","display_name":"Exploratory analysis","level":2,"score":0.274399995803833},{"id":"https://openalex.org/C101601086","wikidata":"https://www.wikidata.org/wiki/Q3753228","display_name":"Rank correlation","level":2,"score":0.26600000262260437},{"id":"https://openalex.org/C2985213535","wikidata":"https://www.wikidata.org/wiki/Q1626599","display_name":"Reference values","level":2,"score":0.26179999113082886},{"id":"https://openalex.org/C3018023364","wikidata":"https://www.wikidata.org/wiki/Q425265","display_name":"Significant difference","level":2,"score":0.2565000057220459}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.3390/sci8110317","doi":"https://doi.org/10.3390/sci8110317","is_oa":true,"landing_page_url":"https://doi.org/10.3390/sci8110317","pdf_url":null,"source":{"id":"https://openalex.org/S4210202795","display_name":"Sci","issn_l":"2413-4155","issn":["2413-4155"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj"],"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Sci","raw_type":"journal-article"}],"best_oa_location":{"id":"doi:10.3390/sci8110317","doi":"https://doi.org/10.3390/sci8110317","is_oa":true,"landing_page_url":"https://doi.org/10.3390/sci8110317","pdf_url":null,"source":{"id":"https://openalex.org/S4210202795","display_name":"Sci","issn_l":"2413-4155","issn":["2413-4155"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj"],"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Sci","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.5683000087738037,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320320879","display_name":"Deutsche Forschungsgemeinschaft","ror":"https://ror.org/018mejw64"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":19,"referenced_works":["https://openalex.org/W1979968489","https://openalex.org/W2007683591","https://openalex.org/W2008152557","https://openalex.org/W2015795623","https://openalex.org/W2019587683","https://openalex.org/W2028672950","https://openalex.org/W2063399989","https://openalex.org/W2067724039","https://openalex.org/W2105552075","https://openalex.org/W2110065044","https://openalex.org/W2950086191","https://openalex.org/W3087149559","https://openalex.org/W4226366125","https://openalex.org/W4241074797","https://openalex.org/W4283359293","https://openalex.org/W4321440702","https://openalex.org/W4321760728","https://openalex.org/W4365483650","https://openalex.org/W4408463052"],"related_works":["https://openalex.org/W7223206711","https://openalex.org/W7165014830","https://openalex.org/W2014441541","https://openalex.org/W4406624064","https://openalex.org/W3185347074","https://openalex.org/W2049696359","https://openalex.org/W2544598231","https://openalex.org/W1999048506","https://openalex.org/W3030624398","https://openalex.org/W3165599762"],"abstract_inverted_index":{"Structural":[0],"MRI":[1],"volumes":[2],"from":[3,150],"different":[4],"field":[5],"strengths":[6],"may":[7],"correlate":[8],"across":[9],"individuals":[10],"yet":[11],"differ":[12],"systematically,":[13],"complicating":[14],"pooling":[15],"and":[16,23,46,59,67,86],"calibration.":[17],"We":[18],"assessed":[19],"paired":[20,74],"3":[21],"T":[22,25],"7":[24],"MP2RAGE":[26],"volumetry":[27],"in":[28,141,163],"22":[29],"healthy":[30],"right-handed":[31],"male":[32],"volunteers":[33],"(of":[34],"32":[35],"initially":[36],"processed;":[37],"10":[38],"excluded":[39],"after":[40],"FreeSurfer":[41],"surface-reconstruction":[42],"failure),":[43],"using":[44],"SynthStrip":[45],"SynthSeg":[47],"on":[48],"reconstructed":[49],"UNI":[50],"images.":[51],"Volumes":[52],"were":[53],"normalised":[54],"to":[55,131,146,152],"total":[56],"intracranial":[57],"volume":[58],"evaluated":[60,96],"for":[61,108,172],"global":[62],"tissue":[63],"classes,":[64],"subcortical":[65],"structures,":[66],"mean":[68,99],"hemispheric":[69],"cortical":[70],"composites.":[71],"Analyses":[72],"included":[73],"Wilcoxon":[75],"tests":[76],"with":[77,97],"false-discovery-rate":[78],"correction,":[79],"Spearman":[80],"correlations,":[81],"absolute-agreement":[82],"ICC(2,1),":[83],"Bland\u2013Altman":[84],"analysis,":[85],"an":[87],"exploratory":[88],"leave-one-out":[89],"comparison":[90],"of":[91],"three":[92],"linear":[93],"calibration":[94,159],"models":[95,160],"symmetric":[98],"absolute":[100,182],"percentage":[101],"error":[102,162],"(sMAPE).":[103],"Rank-order":[104],"association":[105],"was":[106,120,177],"high":[107],"global/subcortical":[109],"measures":[110],"(\u03c1":[111],"=":[112],"0.804\u20130.965,":[113],"all":[114,142,158],"p":[115],"<":[116],"0.001),":[117],"but":[118,168],"agreement":[119],"region-dependent.":[121],"Field-specific":[122],"TIV":[123],"normalisation":[124],"yielded":[125,137],"four":[126,165],"significant":[127,138],"negative":[128],"offsets":[129,184],"(\u22121.00%":[130],"\u22122.20%),":[132],"whereas":[133],"the":[134,155,164,173],"common-denominator/raw-volume":[135],"analysis":[136],"positive":[139],"differences":[140,190],"seven":[143],"regions":[144],"(+1.20%":[145],"+4.35%).":[147],"ICC(2,1)":[148],"ranged":[149],"0.696":[151],"0.980.":[153],"On":[154],"%TIV":[156],"scale,":[157],"reduced":[161],"offset":[166],"regions,":[167],"none":[169],"did":[170],"so":[171],"hippocampus.":[174],"Rank":[175],"order":[176],"preserved":[178],"more":[179],"consistently":[180],"than":[181,192],"agreement;":[183],"should":[185],"be":[186],"interpreted":[187],"as":[188],"scanner-protocol":[189],"rather":[191],"field-strength":[193],"effects":[194],"alone.":[195]},"counts_by_year":[],"updated_date":"2026-10-29T09:56:32.521200","created_date":"2026-10-28T00:00:00"}