{"id":"https://openalex.org/W7223977320","doi":"https://doi.org/10.26180/34818255","title":"SURFactant Administration by SUPraglottic Airway (the SURFSUP 1 Trial): Statistical Analysis Plan","display_name":"SURFactant Administration by SUPraglottic Airway (the SURFSUP 1 Trial): Statistical Analysis Plan","publication_year":2026,"publication_date":"2026-10-27","ids":{"openalex":"https://openalex.org/W7223977320","doi":"https://doi.org/10.26180/34818255"},"language":"en","primary_location":{"id":"doi:10.26180/34818255","doi":"https://doi.org/10.26180/34818255","is_oa":true,"landing_page_url":"https://doi.org/10.26180/34818255","pdf_url":null,"source":{"id":"https://openalex.org/S7407052105","display_name":"Monash University","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Workflow"},"volume":null,"type":"other","is_traditional":false,"indexed_in":["datacite"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://doi.org/10.26180/34818255","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5051138438","display_name":"Calum T. Roberts","orcid":"https://orcid.org/0000-0002-9111-5027","observed_orcids":["https://orcid.org/0000-0002-9111-5027"]},"institutions":[{"id":"https://openalex.org/I56590836","display_name":"Monash University","ror":"https://ror.org/02bfwt286","country_code":"AU","type":"education","lineage":["https://openalex.org/I56590836"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"Calum Roberts","raw_affiliation_strings":["Monash University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Monash University","institution_ids":["https://openalex.org/I56590836"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5055472410","display_name":"Joyce E O\u2019Shea","orcid":"https://orcid.org/0000-0002-3286-3500","observed_orcids":["https://orcid.org/0000-0002-3286-3500"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Joyce E O'Shea","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5032226344","display_name":"Miranda L. Davies-Tuck","orcid":"https://orcid.org/0000-0003-1918-5538","observed_orcids":["https://orcid.org/0000-0003-1918-5538"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Miranda Davies-Tuck","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5129688964","display_name":"PETER DAVIS","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I165779595","display_name":"The University of Melbourne","ror":"https://ror.org/01ej9dk98","country_code":"AU","type":"education","lineage":["https://openalex.org/I165779595"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"PETER DAVIS","raw_affiliation_strings":["University of Melbourne"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Melbourne","institution_ids":["https://openalex.org/I165779595"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5159914527","display_name":"Peter Dargaville","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I129801699","display_name":"University of Tasmania","ror":"https://ror.org/01nfmeh72","country_code":"AU","type":"education","lineage":["https://openalex.org/I129801699"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"Peter Dargaville","raw_affiliation_strings":["University of Tasmania"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Tasmania","institution_ids":["https://openalex.org/I129801699"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5014303691","display_name":"Kate Alison Hodgson","orcid":"https://orcid.org/0000-0002-2908-1049","observed_orcids":["https://orcid.org/0000-0002-2908-1049","https://orcid.org/0000-0003-3614-2388"]},"institutions":[{"id":"https://openalex.org/I165779595","display_name":"The University of Melbourne","ror":"https://ror.org/01ej9dk98","country_code":"AU","type":"education","lineage":["https://openalex.org/I165779595"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"Kate Hodgson","raw_affiliation_strings":["University of Melbourne"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Melbourne","institution_ids":["https://openalex.org/I165779595"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5159936672","display_name":"LOUISE OWEN","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I165779595","display_name":"The University of Melbourne","ror":"https://ror.org/01ej9dk98","country_code":"AU","type":"education","lineage":["https://openalex.org/I165779595"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"LOUISE OWEN","raw_affiliation_strings":["University of Melbourne"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Melbourne","institution_ids":["https://openalex.org/I165779595"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10549","display_name":"Neonatal Respiratory Health Research","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10549","display_name":"Neonatal Respiratory Health Research","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10322","display_name":"Respiratory Support and Mechanisms","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11060","display_name":"Infant Development and Preterm Care","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2735","display_name":"Pediatrics, Perinatology and Child Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/surfactant-replacement-therapy","display_name":"surfactant therapy","score":0.8309999704360962},{"id":"https://openalex.org/keywords/supraglottic-airway-devices","display_name":"supraglottic airway devices","score":0.9440000057220459},{"id":"https://openalex.org/keywords/preterm-infants","display_name":"preterm infants","score":0.8980000019073486},{"id":"https://openalex.org/keywords/respiratory-distress-syndrome","display_name":"respiratory distress syndrome","score":0.9779999852180481},{"id":"https://openalex.org/keywords/non-inferiority","display_name":"non-inferiority","score":0.8949999809265137},{"id":"https://openalex.org/keywords/mechanical-ventilation","display_name":"mechanical ventilation","score":0.8999999761581421},{"id":"https://openalex.org/keywords/neonatal-respiratory-support","display_name":"neonatal respiratory support","score":0.6740000247955322}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8927000164985657},{"id":"https://openalex.org/C2909712316","wikidata":"https://www.wikidata.org/wiki/Q28653627","display_name":"Supraglottic airway","level":4,"score":0.6208000183105469},{"id":"https://openalex.org/C58226133","wikidata":"https://www.wikidata.org/wiki/Q1324199","display_name":"Pulmonary surfactant","level":2,"score":0.5989999771118164},{"id":"https://openalex.org/C141983124","wikidata":"https://www.wikidata.org/wiki/Q188008","display_name":"Respiratory distress","level":2,"score":0.5954999923706055},{"id":"https://openalex.org/C2776888792","wikidata":"https://www.wikidata.org/wiki/Q2357917","display_name":"Laryngoscopy","level":3,"score":0.5871000289916992},{"id":"https://openalex.org/C42219234","wikidata":"https://www.wikidata.org/wiki/Q131130","display_name":"Anesthesia","level":1,"score":0.5720999836921692},{"id":"https://openalex.org/C2986587452","wikidata":"https://www.wikidata.org/wiki/Q938438","display_name":"Statistical analysis","level":2,"score":0.5249000191688538},{"id":"https://openalex.org/C535046627","wikidata":"https://www.wikidata.org/wiki/Q30612","display_name":"Clinical trial","level":2,"score":0.4778999984264374},{"id":"https://openalex.org/C2777080012","wikidata":"https://www.wikidata.org/wiki/Q3766250","display_name":"Mechanical ventilation","level":2,"score":0.47600001096725464},{"id":"https://openalex.org/C105922876","wikidata":"https://www.wikidata.org/wiki/Q1423981","display_name":"Airway","level":2,"score":0.45419999957084656},{"id":"https://openalex.org/C200457457","wikidata":"https://www.wikidata.org/wiki/Q584049","display_name":"Ventilation (architecture)","level":2,"score":0.4027999937534332},{"id":"https://openalex.org/C168563851","wikidata":"https://www.wikidata.org/wiki/Q1436668","display_name":"Randomized controlled trial","level":2,"score":0.38960000872612},{"id":"https://openalex.org/C177713679","wikidata":"https://www.wikidata.org/wiki/Q679690","display_name":"Intensive care medicine","level":1,"score":0.35120001435279846},{"id":"https://openalex.org/C2778716859","wikidata":"https://www.wikidata.org/wiki/Q939018","display_name":"Intubation","level":2,"score":0.3416999876499176},{"id":"https://openalex.org/C2994577977","wikidata":"https://www.wikidata.org/wiki/Q1203526","display_name":"Pilot trial","level":3,"score":0.29649999737739563},{"id":"https://openalex.org/C2779547634","wikidata":"https://www.wikidata.org/wiki/Q5165502","display_name":"Continuous positive airway pressure","level":3,"score":0.2809000015258789},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.2757999897003174},{"id":"https://openalex.org/C2778029997","wikidata":"https://www.wikidata.org/wiki/Q750195","display_name":"Tracheal intubation","level":3,"score":0.2734000086784363},{"id":"https://openalex.org/C2776953283","wikidata":"https://www.wikidata.org/wiki/Q17125052","display_name":"Surfactant therapy","level":4,"score":0.25519999861717224},{"id":"https://openalex.org/C534529494","wikidata":"https://www.wikidata.org/wiki/Q7891","display_name":"Respiratory system","level":2,"score":0.2524999976158142}],"mesh":[],"locations_count":2,"locations":[{"id":"doi:10.26180/34818255","doi":"https://doi.org/10.26180/34818255","is_oa":true,"landing_page_url":"https://doi.org/10.26180/34818255","pdf_url":null,"source":{"id":"https://openalex.org/S7407052105","display_name":"Monash University","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Workflow"},{"id":"doi:10.26180/34818255.v1","doi":"https://doi.org/10.26180/34818255.v1","is_oa":true,"landing_page_url":"https://doi.org/10.26180/34818255.v1","pdf_url":null,"source":{"id":"https://openalex.org/S7407052105","display_name":"Monash University","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Workflow"}],"best_oa_location":{"id":"doi:10.26180/34818255","doi":"https://doi.org/10.26180/34818255","is_oa":true,"landing_page_url":"https://doi.org/10.26180/34818255","pdf_url":null,"source":{"id":"https://openalex.org/S7407052105","display_name":"Monash University","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Workflow"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.9537000060081482}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320334705","display_name":"National Health and Medical Research Council","ror":"https://ror.org/011kf5r70"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W4416844593","https://openalex.org/W3113353924","https://openalex.org/W4386864641","https://openalex.org/W6977286089","https://openalex.org/W2040861967","https://openalex.org/W7214928555","https://openalex.org/W3091604953","https://openalex.org/W2158576990","https://openalex.org/W6902162730","https://openalex.org/W2244162321"],"abstract_inverted_index":{"The":[0,12,58],"SURFSUP":[1],"1":[2],"Trial":[3,99,102],"is":[4,14,21],"a":[5,52],"multi-centre,":[6],"unblinded,":[7],"randomised":[8],"controlled,":[9],"non-inferiority":[10],"trial.":[11],"trial":[13,59,90,96],"investigating":[15],"whether":[16],"supraglottic":[17],"airway":[18],"surfactant":[19,26,42],"treatment":[20,27],"non-inferior":[22],"to":[23,61],"minimally":[24],"invasive":[25],"(MIST)":[28],"provided":[29],"by":[30],"laryngoscopy":[31],"and":[32,80],"thin":[33],"catheter,":[34],"in":[35,48,68,72,77,83,94],"preventing":[36],"mechanical":[37],"ventilation":[38],"(MV)":[39],"or":[40],"repeat":[41],"within":[43],"72":[44],"hours":[45],"of":[46,54,88],"randomisation,":[47],"preterm":[49,66],"infants":[50,67],"with":[51],"diagnosis":[53],"respiratory":[55],"distress":[56],"syndrome.":[57],"aimed":[60],"enrol":[62],"at":[63],"least":[64],"1000":[65],"57":[69],"neonatal":[70],"units":[71],"seven":[73],"countries.":[74],"Enrolment":[75],"commenced":[76],"February":[78],"2021":[79],"was":[81],"completed":[82],"August":[84],"2026.":[85],"Full":[86],"details":[87],"the":[89,95],"design":[91],"are":[92],"available":[93],"protocol.RegistrationWHO":[97],"Universal":[98],"Number:":[100],"U1111-1258-2109ANZCTR":[101],"ID:":[103],"ACTRN12620001184965":[104]},"counts_by_year":[],"updated_date":"2026-10-29T09:56:32.521200","created_date":"2026-10-28T00:00:00"}