{"id":"https://openalex.org/W7223966709","doi":"https://doi.org/10.1186/s12894-026-02364-2","title":"Development and validation of a pre-stratified strategy for predicting clinically significant prostate cancer in PI-RADS 3 lesions","display_name":"Development and validation of a pre-stratified strategy for predicting clinically significant prostate cancer in PI-RADS 3 lesions","publication_year":2026,"publication_date":"2026-10-28","ids":{"openalex":"https://openalex.org/W7223966709","doi":"https://doi.org/10.1186/s12894-026-02364-2"},"language":"en","primary_location":{"id":"doi:10.1186/s12894-026-02364-2","doi":"https://doi.org/10.1186/s12894-026-02364-2","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s12894-026-02364-2","pdf_url":null,"source":{"id":"https://openalex.org/S155033327","display_name":"BMC Urology","issn_l":"1471-2490","issn":["1471-2490"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Urology","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://doi.org/10.1186/s12894-026-02364-2","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5100420461","display_name":"Hong Chen","orcid":"https://orcid.org/0000-0003-0921-2547","observed_orcids":["https://orcid.org/0000-0003-0921-2547"]},"institutions":[{"id":"https://openalex.org/I4210166576","display_name":"First Affiliated Hospital Zhejiang University","ror":"https://ror.org/05m1p5x56","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210166576"]},{"id":"https://openalex.org/I76130692","display_name":"Zhejiang University","ror":"https://ror.org/00a2xv884","country_code":"CN","type":"education","lineage":["https://openalex.org/I76130692"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Hong Chen","raw_affiliation_strings":["Department of Urology, The First Affiliated Hospital, Zhejiang University School of Medicine, Qingchun Road 79, Hangzhou, Zhejiang, 310003, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Urology, The First Affiliated Hospital, Zhejiang University School of Medicine, Qingchun Road 79, Hangzhou, Zhejiang, 310003, China","institution_ids":["https://openalex.org/I4210166576","https://openalex.org/I76130692"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5159811876","display_name":"Boqing Zhu","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210166576","display_name":"First Affiliated Hospital Zhejiang University","ror":"https://ror.org/05m1p5x56","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210166576"]},{"id":"https://openalex.org/I76130692","display_name":"Zhejiang University","ror":"https://ror.org/00a2xv884","country_code":"CN","type":"education","lineage":["https://openalex.org/I76130692"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Boqing Zhu","raw_affiliation_strings":["Department of Urology, The First Affiliated Hospital, Zhejiang University School of Medicine, Qingchun Road 79, Hangzhou, Zhejiang, 310003, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Urology, The First Affiliated Hospital, Zhejiang University School of Medicine, Qingchun Road 79, Hangzhou, Zhejiang, 310003, China","institution_ids":["https://openalex.org/I4210166576","https://openalex.org/I76130692"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5159797434","display_name":"Jiangfeng Li","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210166576","display_name":"First Affiliated Hospital Zhejiang University","ror":"https://ror.org/05m1p5x56","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210166576"]},{"id":"https://openalex.org/I76130692","display_name":"Zhejiang University","ror":"https://ror.org/00a2xv884","country_code":"CN","type":"education","lineage":["https://openalex.org/I76130692"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Jiangfeng Li","raw_affiliation_strings":["Department of Urology, The First Affiliated Hospital, Zhejiang University School of Medicine, Qingchun Road 79, Hangzhou, Zhejiang, 310003, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Urology, The First Affiliated Hospital, Zhejiang University School of Medicine, Qingchun Road 79, Hangzhou, Zhejiang, 310003, China","institution_ids":["https://openalex.org/I4210166576","https://openalex.org/I76130692"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5159866805","display_name":"Jian Wu","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210166576","display_name":"First Affiliated Hospital Zhejiang University","ror":"https://ror.org/05m1p5x56","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210166576"]},{"id":"https://openalex.org/I76130692","display_name":"Zhejiang University","ror":"https://ror.org/00a2xv884","country_code":"CN","type":"education","lineage":["https://openalex.org/I76130692"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Jian Wu","raw_affiliation_strings":["Department of Urology, The First Affiliated Hospital, Zhejiang University School of Medicine, Qingchun Road 79, Hangzhou, Zhejiang, 310003, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Urology, The First Affiliated Hospital, Zhejiang University School of Medicine, Qingchun Road 79, Hangzhou, Zhejiang, 310003, China","institution_ids":["https://openalex.org/I4210166576","https://openalex.org/I76130692"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5159939743","display_name":"Xiangyi Zheng","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210166576","display_name":"First Affiliated Hospital Zhejiang University","ror":"https://ror.org/05m1p5x56","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210166576"]},{"id":"https://openalex.org/I76130692","display_name":"Zhejiang University","ror":"https://ror.org/00a2xv884","country_code":"CN","type":"education","lineage":["https://openalex.org/I76130692"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Xiangyi Zheng","raw_affiliation_strings":["Department of Urology, The First Affiliated Hospital, Zhejiang University School of Medicine, Qingchun Road 79, Hangzhou, Zhejiang, 310003, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Urology, The First Affiliated Hospital, Zhejiang University School of Medicine, Qingchun Road 79, Hangzhou, Zhejiang, 310003, China","institution_ids":["https://openalex.org/I4210166576","https://openalex.org/I76130692"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100462064","display_name":"Ben Liu","orcid":"https://orcid.org/0000-0002-0709-6784","observed_orcids":["https://orcid.org/0000-0002-0709-6784"]},"institutions":[{"id":"https://openalex.org/I4210166576","display_name":"First Affiliated Hospital Zhejiang University","ror":"https://ror.org/05m1p5x56","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210166576"]},{"id":"https://openalex.org/I76130692","display_name":"Zhejiang University","ror":"https://ror.org/00a2xv884","country_code":"CN","type":"education","lineage":["https://openalex.org/I76130692"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Ben Liu","raw_affiliation_strings":["Department of Urology, The First Affiliated Hospital, Zhejiang University School of Medicine, Qingchun Road 79, Hangzhou, Zhejiang, 310003, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Urology, The First Affiliated Hospital, Zhejiang University School of Medicine, Qingchun Road 79, Hangzhou, Zhejiang, 310003, China","institution_ids":["https://openalex.org/I4210166576","https://openalex.org/I76130692"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5159805014","display_name":"Liping Xie","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210166576","display_name":"First Affiliated Hospital Zhejiang University","ror":"https://ror.org/05m1p5x56","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210166576"]},{"id":"https://openalex.org/I76130692","display_name":"Zhejiang University","ror":"https://ror.org/00a2xv884","country_code":"CN","type":"education","lineage":["https://openalex.org/I76130692"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Liping Xie","raw_affiliation_strings":["Department of Urology, The First Affiliated Hospital, Zhejiang University School of Medicine, Qingchun Road 79, Hangzhou, Zhejiang, 310003, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Urology, The First Affiliated Hospital, Zhejiang University School of Medicine, Qingchun Road 79, Hangzhou, Zhejiang, 310003, China","institution_ids":["https://openalex.org/I4210166576","https://openalex.org/I76130692"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5100411441","display_name":"Xiao Wang","orcid":"https://orcid.org/0000-0001-8824-6280","observed_orcids":["https://orcid.org/0000-0001-8824-6280"]},"institutions":[{"id":"https://openalex.org/I4210166576","display_name":"First Affiliated Hospital Zhejiang University","ror":"https://ror.org/05m1p5x56","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210166576"]},{"id":"https://openalex.org/I76130692","display_name":"Zhejiang University","ror":"https://ror.org/00a2xv884","country_code":"CN","type":"education","lineage":["https://openalex.org/I76130692"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Xiao Wang","raw_affiliation_strings":["Department of Urology, The First Affiliated Hospital, Zhejiang University School of Medicine, Qingchun Road 79, Hangzhou, Zhejiang, 310003, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Urology, The First Affiliated Hospital, Zhejiang University School of Medicine, Qingchun Road 79, Hangzhou, Zhejiang, 310003, China","institution_ids":["https://openalex.org/I4210166576","https://openalex.org/I76130692"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5100411441"],"corresponding_institution_ids":["https://openalex.org/I4210166576","https://openalex.org/I76130692"],"apc_list":{"value":2990,"currency":"USD","value_usd":2990},"apc_paid":{"value":2990,"currency":"USD","value_usd":2990},"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.85930028,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10124","display_name":"Prostate Cancer Diagnosis and Treatment","score":0.9810000061988831,"subfield":{"id":"https://openalex.org/subfields/2748","display_name":"Urology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10124","display_name":"Prostate Cancer Diagnosis and Treatment","score":0.9810000061988831,"subfield":{"id":"https://openalex.org/subfields/2748","display_name":"Urology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12422","display_name":"Radiomics and Machine Learning in Medical Imaging","score":0.009499999694526196,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11885","display_name":"MRI in cancer diagnosis","score":0.0010999999940395355,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/prostate-cancer","display_name":"prostate cancer","score":0.8769999742507935},{"id":"https://openalex.org/keywords/pi-rads-3","display_name":"PI-RADS 3","score":0.8610000014305115},{"id":"https://openalex.org/keywords/clinically-significant-prostate-cancer","display_name":"clinically significant prostate cancer","score":0.8109999895095825},{"id":"https://openalex.org/keywords/model-validation","display_name":"model validation","score":0.45100000500679016},{"id":"https://openalex.org/keywords/prostate-cancer-detection","display_name":"prostate cancer detection","score":0.34299999475479126}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.957099974155426},{"id":"https://openalex.org/C2780192828","wikidata":"https://www.wikidata.org/wiki/Q181257","display_name":"Prostate cancer","level":3,"score":0.7501999735832214},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.5663999915122986},{"id":"https://openalex.org/C143998085","wikidata":"https://www.wikidata.org/wiki/Q162555","display_name":"Oncology","level":1,"score":0.5497000217437744},{"id":"https://openalex.org/C2779473830","wikidata":"https://www.wikidata.org/wiki/Q1540899","display_name":"MEDLINE","level":2,"score":0.37139999866485596},{"id":"https://openalex.org/C2779466945","wikidata":"https://www.wikidata.org/wiki/Q1765251","display_name":"Prostatectomy","level":4,"score":0.3179999887943268},{"id":"https://openalex.org/C198433322","wikidata":"https://www.wikidata.org/wiki/Q3910099","display_name":"Predictive value of tests","level":2,"score":0.30149999260902405},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.28760001063346863},{"id":"https://openalex.org/C2781406297","wikidata":"https://www.wikidata.org/wiki/Q409450","display_name":"Prostate-specific antigen","level":4,"score":0.2851000130176544},{"id":"https://openalex.org/C3018130915","wikidata":"https://www.wikidata.org/wiki/Q1752284","display_name":"Neoplasm staging","level":3,"score":0.28439998626708984},{"id":"https://openalex.org/C126838900","wikidata":"https://www.wikidata.org/wiki/Q77604","display_name":"Radiology","level":1,"score":0.27469998598098755},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.2646999955177307},{"id":"https://openalex.org/C71472368","wikidata":"https://www.wikidata.org/wiki/Q676880","display_name":"Text mining","level":2,"score":0.2549000084400177},{"id":"https://openalex.org/C509974204","wikidata":"https://www.wikidata.org/wiki/Q180507","display_name":"Radiation therapy","level":2,"score":0.2533999979496002}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1186/s12894-026-02364-2","doi":"https://doi.org/10.1186/s12894-026-02364-2","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s12894-026-02364-2","pdf_url":null,"source":{"id":"https://openalex.org/S155033327","display_name":"BMC Urology","issn_l":"1471-2490","issn":["1471-2490"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Urology","raw_type":"journal-article"}],"best_oa_location":{"id":"doi:10.1186/s12894-026-02364-2","doi":"https://doi.org/10.1186/s12894-026-02364-2","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s12894-026-02364-2","pdf_url":null,"source":{"id":"https://openalex.org/S155033327","display_name":"BMC Urology","issn_l":"1471-2490","issn":["1471-2490"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Urology","raw_type":"journal-article"},"sustainable_development_goals":[{"score":1.0,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[],"funders":[{"id":"https://openalex.org/F8142712028","display_name":"Key Research and Development Program of Zhejiang Province","ror":null}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W4282028071","https://openalex.org/W4282048032","https://openalex.org/W4404144414","https://openalex.org/W3112546661","https://openalex.org/W4319955585","https://openalex.org/W4393854335","https://openalex.org/W7208731233","https://openalex.org/W7221021682","https://openalex.org/W4404144681","https://openalex.org/W6945694555"],"abstract_inverted_index":{"The":[0,94,216,267],"optimal":[1],"management":[2,305],"of":[3,88,126,163,214,229,247,254,260,265,269,279,292,297,321,329],"patients":[4,38,151,165,293,308],"with":[5,52,142,155,226,257,309],"Prostate":[6],"Imaging":[7],"Reporting":[8],"and":[9,43,66,76,112,133,152,197,262,281],"Data":[10],"System":[11],"(PI-RADS)":[12],"3":[13,54,311],"lesions":[14,55],"remains":[15],"a":[16,32,236,258,263,302,326],"clinical":[17],"dilemma,":[18],"primarily":[19],"due":[20],"to":[21,30,40,73,84,272],"the":[22,101,104,123,130,136,161,232,240,270,273,282],"lesions\u2019":[23],"intermediate":[24],"risk":[25],"profile.":[26],"This":[27,46,299,313],"study":[28,48,300],"aimed":[29],"develop":[31],"risk-adapted":[33,304],"decision-making":[34],"strategy":[35,243,285,306],"by":[36],"pre-stratifying":[37],"according":[39,72],"biopsy":[41,62,74,242,284,289],"history":[42,75],"lesion":[44,77],"location.":[45,78],"retrospective":[47],"included":[49],"919":[50,127],"men":[51],"PI-RADS":[53,310],"on":[56],"mpMRI":[57],"who":[58],"underwent":[59],"systematic":[60],"prostate":[61,91],"between":[63],"January":[64],"2022":[65],"June":[67],"2025.":[68],"Patients":[69],"were":[70,115,140],"stratified":[71],"Multivariable":[79],"logistic":[80,170],"regression":[81,171],"was":[82,98,145],"employed":[83],"identify":[85],"independent":[86,212],"predictors":[87,213],"clinically":[89],"significant":[90],"cancer":[92],"(csPCa).":[93],"model\u2019s":[95],"discriminative":[96],"performance":[97],"assessed":[99],"using":[100],"area":[102],"under":[103],"receiver":[105],"operating":[106],"characteristic":[107],"curve":[108,119],"(AUC).":[109],"Clinical":[110],"utility":[111],"net":[113],"benefit":[114],"evaluated":[116],"via":[117],"decision":[118],"analysis":[120],"(DCA).":[121],"Among":[122],"overall":[124],"cohort":[125,275],"patients\u2014684":[128],"in":[129,135,149,153,231,290],"training":[131,233],"set":[132],"235":[134],"validation":[137,274],"set\u2014152":[138],"(16.5%)":[139],"diagnosed":[141],"csPCa.":[143,215,298],"csPCa":[144,255,331],"more":[146],"frequently":[147],"detected":[148],"biopsy-naive":[150,164],"those":[154],"peripheral":[156],"zone":[157],"(PZ)":[158],"lesions.":[159,312],"In":[160],"subgroup":[162],"without":[166],"PZ":[167],"lesions,":[168],"multivariable":[169],"identified":[172],"age":[173],"(OR":[174,184,202],"=":[175,185,203],"1.07,":[176],"95%":[177,187,205],"CI":[178,188,206],"1.01\u20131.13;":[179],"P":[180,194,208],"<":[181,195,209],"0.05),":[182],"f/tPSA":[183],"0.0001352,":[186],"2.823e":[189],"\u2212":[190],"7":[191],"-":[192],"0.02962;":[193],"0.01),":[196],"prostate\u2011specific":[198],"antigen":[199],"density":[200],"(PSAD)":[201],"5.34,":[204],"1.69\u201324.84;":[207],"0.05)":[210],"as":[211],"final":[217],"model":[218,271],"combining":[219],"these":[220],"three":[221],"variables":[222],"showed":[223],"excellent":[224],"discrimination,":[225],"an":[227,277],"AUC":[228,278],"0.839":[230],"cohort.":[234],"Using":[235],"10%":[237],"probability":[238],"threshold,":[239],"optimized":[241,283,314],"would":[244,286,316],"avert":[245],"44.6%":[246],"immediate":[248],"biopsies":[249,323],"while":[250,294,324],"missing":[251,295],"only":[252],"7.6%":[253],"cases":[256],"sensitivity":[259],"86%":[261],"specificity":[264],"72.5%.":[266],"application":[268],"achieved":[276],"0.746":[280],"have":[287,317],"deferred":[288,318],"43.8%":[291],"14.7%":[296],"proposed":[301],"novel,":[303],"for":[307],"approach":[315],"nearly":[319],"half":[320],"unnecessary":[322],"maintaining":[325],"low":[327],"rate":[328],"missed":[330],"diagnoses.":[332]},"counts_by_year":[],"updated_date":"2026-10-30T12:39:25.321706","created_date":"2026-10-28T00:00:00"}