{"id":"https://openalex.org/W7223701574","doi":"https://doi.org/10.1152/ajpheart.90085.2026","title":"Effect of diet-induced plasma ceramide on human in vivo microvascular endothelial function","display_name":"Effect of diet-induced plasma ceramide on human in vivo microvascular endothelial function","publication_year":2026,"publication_date":"2026-10-26","ids":{"openalex":"https://openalex.org/W7223701574","doi":"https://doi.org/10.1152/ajpheart.90085.2026","pmid":"https://pubmed.ncbi.nlm.nih.gov/42932507"},"language":"en","primary_location":{"id":"doi:10.1152/ajpheart.90085.2026","doi":"https://doi.org/10.1152/ajpheart.90085.2026","is_oa":true,"landing_page_url":"https://doi.org/10.1152/ajpheart.90085.2026","pdf_url":null,"source":{"id":"https://openalex.org/S87338489","display_name":"American Journal of Physiology-Heart and Circulatory Physiology","issn_l":"0363-6135","issn":["0363-6135","1522-1539"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-a","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320261","host_organization_name":"American Physical Society","host_organization_lineage":["https://openalex.org/P4310320261"],"host_organization_lineage_names":["American Physical Society"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"American Journal of Physiology-Heart and Circulatory Physiology","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://doi.org/10.1152/ajpheart.90085.2026","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5062206894","display_name":"Tijana Simovic","orcid":"https://orcid.org/0000-0002-3613-4196","observed_orcids":["https://orcid.org/0000-0002-3613-4196"]},"institutions":[{"id":"https://openalex.org/I204308271","display_name":"Medical College of Wisconsin","ror":"https://ror.org/00qqv6244","country_code":"US","type":"education","lineage":["https://openalex.org/I204308271"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Tijana Simovic","raw_affiliation_strings":["Medical College of Wisconsin"],"raw_orcid":"https://orcid.org/0000-0002-3613-4196","affiliations":[{"raw_affiliation_string":"Medical College of Wisconsin","institution_ids":["https://openalex.org/I204308271"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5092098557","display_name":"Maria Jose Jaramillo-Torres","orcid":"https://orcid.org/0009-0008-2033-0273","observed_orcids":["https://orcid.org/0009-0008-2033-0273"]},"institutions":[{"id":"https://openalex.org/I204308271","display_name":"Medical College of Wisconsin","ror":"https://ror.org/00qqv6244","country_code":"US","type":"education","lineage":["https://openalex.org/I204308271"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Maria J. Jaramillo-Torres","raw_affiliation_strings":["Medical College of Wisconsin"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Medical College of Wisconsin","institution_ids":["https://openalex.org/I204308271"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5116245455","display_name":"William Butak","orcid":"https://orcid.org/0009-0005-5493-5295","observed_orcids":["https://orcid.org/0009-0005-5493-5295"]},"institutions":[{"id":"https://openalex.org/I204308271","display_name":"Medical College of Wisconsin","ror":"https://ror.org/00qqv6244","country_code":"US","type":"education","lineage":["https://openalex.org/I204308271"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"William J. Butak","raw_affiliation_strings":["Medical College of Wisconsin"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Medical College of Wisconsin","institution_ids":["https://openalex.org/I204308271"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103617965","display_name":"Emily M. O\u2019Connell","orcid":"https://orcid.org/0009-0003-7330-3467","observed_orcids":["https://orcid.org/0009-0003-7330-3467"]},"institutions":[{"id":"https://openalex.org/I204308271","display_name":"Medical College of Wisconsin","ror":"https://ror.org/00qqv6244","country_code":"US","type":"education","lineage":["https://openalex.org/I204308271"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Emily M. O\u2019Connell","raw_affiliation_strings":["Medical College of Wisconsin"],"raw_orcid":"https://orcid.org/0009-0003-7330-3467","affiliations":[{"raw_affiliation_string":"Medical College of Wisconsin","institution_ids":["https://openalex.org/I204308271"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5028980866","display_name":"Gopika SenthilKumar","orcid":"https://orcid.org/0000-0001-5781-1056","observed_orcids":["https://orcid.org/0000-0001-5781-1056"]},"institutions":[{"id":"https://openalex.org/I204308271","display_name":"Medical College of Wisconsin","ror":"https://ror.org/00qqv6244","country_code":"US","type":"education","lineage":["https://openalex.org/I204308271"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Gopika Senthilkumar","raw_affiliation_strings":["Medical College of Wisconsin"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Medical College of Wisconsin","institution_ids":["https://openalex.org/I204308271"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5104212431","display_name":"Haoran Teng","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I204308271","display_name":"Medical College of Wisconsin","ror":"https://ror.org/00qqv6244","country_code":"US","type":"education","lineage":["https://openalex.org/I204308271"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Haoran Teng","raw_affiliation_strings":["Medical College of Wisconsin"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Medical College of Wisconsin","institution_ids":["https://openalex.org/I204308271"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5031961745","display_name":"Kai Yang","orcid":"https://orcid.org/0000-0003-3044-2240","observed_orcids":["https://orcid.org/0000-0003-3044-2240","https://orcid.org/0000-0003-1923-2859","https://orcid.org/0000-0002-9966-1380","https://orcid.org/0009-0006-2782-4888","https://orcid.org/0009-0007-5482-1081"]},"institutions":[{"id":"https://openalex.org/I204308271","display_name":"Medical College of Wisconsin","ror":"https://ror.org/00qqv6244","country_code":"US","type":"education","lineage":["https://openalex.org/I204308271"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Kai Yang","raw_affiliation_strings":["Medical College of Wisconsin"],"raw_orcid":"https://orcid.org/0000-0002-9966-1380","affiliations":[{"raw_affiliation_string":"Medical College of Wisconsin","institution_ids":["https://openalex.org/I204308271"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5066805752","display_name":"Matthew J. Durand","orcid":"https://orcid.org/0000-0002-1416-1652","observed_orcids":["https://orcid.org/0000-0002-1416-1652"]},"institutions":[{"id":"https://openalex.org/I204308271","display_name":"Medical College of Wisconsin","ror":"https://ror.org/00qqv6244","country_code":"US","type":"education","lineage":["https://openalex.org/I204308271"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Matthew J. Durand","raw_affiliation_strings":["Medical College of Wisconsin"],"raw_orcid":"https://orcid.org/0000-0002-1416-1652","affiliations":[{"raw_affiliation_string":"Medical College of Wisconsin","institution_ids":["https://openalex.org/I204308271"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5047276993","display_name":"Julie K. Freed","orcid":"https://orcid.org/0000-0002-9367-2281","observed_orcids":["https://orcid.org/0000-0002-9367-2281"]},"institutions":[{"id":"https://openalex.org/I204308271","display_name":"Medical College of Wisconsin","ror":"https://ror.org/00qqv6244","country_code":"US","type":"education","lineage":["https://openalex.org/I204308271"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Julie K. Freed","raw_affiliation_strings":["Medical College of Wisconsin"],"raw_orcid":"https://orcid.org/0000-0002-9367-2281","affiliations":[{"raw_affiliation_string":"Medical College of Wisconsin","institution_ids":["https://openalex.org/I204308271"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5062206894","https://openalex.org/A5092098557"],"corresponding_institution_ids":["https://openalex.org/I204308271"],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.73198724,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"331","issue":"5","first_page":"H1718","last_page":"H1730"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11308","display_name":"Sphingolipid Metabolism and Signaling","score":0.8881999850273132,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11308","display_name":"Sphingolipid Metabolism and Signaling","score":0.8881999850273132,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10155","display_name":"Nitric Oxide and Endothelin Effects","score":0.04450000077486038,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12964","display_name":"Diet, Metabolism, and Disease","score":0.019500000402331352,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/ceramide","display_name":"ceramide","score":0.6890000104904175},{"id":"https://openalex.org/keywords/plasma-ceramides","display_name":"plasma ceramides","score":0.671999990940094},{"id":"https://openalex.org/keywords/microvascular-endothelial-function","display_name":"microvascular endothelial function","score":0.9150000214576721},{"id":"https://openalex.org/keywords/long-chain-fatty-acids","display_name":"long-chain fatty acids","score":0.8569999933242798},{"id":"https://openalex.org/keywords/medium-chain-fatty-acids","display_name":"medium-chain fatty acids","score":0.9110000133514404},{"id":"https://openalex.org/keywords/sex-differences","display_name":"sex differences","score":0.7039999961853027},{"id":"https://openalex.org/keywords/dietary-fat","display_name":"dietary fat","score":0.5120000243186951},{"id":"https://openalex.org/keywords/cardiovascular-risk","display_name":"cardiovascular risk","score":0.5120000243186951}],"concepts":[{"id":"https://openalex.org/C207001950","wikidata":"https://www.wikidata.org/wiki/Q141124","display_name":"In vivo","level":2,"score":0.7689999938011169},{"id":"https://openalex.org/C2777851122","wikidata":"https://www.wikidata.org/wiki/Q424213","display_name":"Ceramide","level":3,"score":0.6819000244140625},{"id":"https://openalex.org/C14036430","wikidata":"https://www.wikidata.org/wiki/Q3736076","display_name":"Function (biology)","level":2,"score":0.5950000286102295},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.5795000195503235},{"id":"https://openalex.org/C2776992346","wikidata":"https://www.wikidata.org/wiki/Q111140","display_name":"Endothelium","level":2,"score":0.5717999935150146},{"id":"https://openalex.org/C2780972559","wikidata":"https://www.wikidata.org/wiki/Q550061","display_name":"Endothelial dysfunction","level":2,"score":0.48260000348091125},{"id":"https://openalex.org/C12722491","wikidata":"https://www.wikidata.org/wiki/Q1632335","display_name":"Microcirculation","level":2,"score":0.4352000057697296},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.4302000105381012},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.42719998955726624},{"id":"https://openalex.org/C123012128","wikidata":"https://www.wikidata.org/wiki/Q5376430","display_name":"Endothelial stem cell","level":3,"score":0.362199991941452},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.323199987411499},{"id":"https://openalex.org/C2777663904","wikidata":"https://www.wikidata.org/wiki/Q988343","display_name":"Blood vessel","level":2,"score":0.31040000915527344},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.30079999566078186},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.27309998869895935},{"id":"https://openalex.org/C543025807","wikidata":"https://www.wikidata.org/wiki/Q61476","display_name":"Fatty acid","level":2,"score":0.2685000002384186},{"id":"https://openalex.org/C44353895","wikidata":"https://www.wikidata.org/wiki/Q6556772","display_name":"Lipotoxicity","level":4,"score":0.25049999356269836}],"mesh":[{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002518","descriptor_name":"Ceramides","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true},{"descriptor_ui":"D004311","descriptor_name":"Double-Blind Method","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004730","descriptor_name":"Endothelium, Vascular","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D004730","descriptor_name":"Endothelium, Vascular","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D004730","descriptor_name":"Endothelium, Vascular","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":true},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008833","descriptor_name":"Microcirculation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012737","descriptor_name":"Sex Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014664","descriptor_name":"Vasodilation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D017078","descriptor_name":"Laser-Doppler Flowmetry","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018592","descriptor_name":"Cross-Over Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019518","descriptor_name":"Postprandial Period","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D055806","descriptor_name":"Microvessels","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D055806","descriptor_name":"Microvessels","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D055815","descriptor_name":"Young Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D059305","descriptor_name":"Diet, High-Fat","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1152/ajpheart.90085.2026","doi":"https://doi.org/10.1152/ajpheart.90085.2026","is_oa":true,"landing_page_url":"https://doi.org/10.1152/ajpheart.90085.2026","pdf_url":null,"source":{"id":"https://openalex.org/S87338489","display_name":"American Journal of Physiology-Heart and Circulatory Physiology","issn_l":"0363-6135","issn":["0363-6135","1522-1539"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-a","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320261","host_organization_name":"American Physical Society","host_organization_lineage":["https://openalex.org/P4310320261"],"host_organization_lineage_names":["American Physical Society"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"American Journal of Physiology-Heart and Circulatory Physiology","raw_type":"journal-article"},{"id":"pmid:42932507","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/42932507","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"American journal of physiology. Heart and circulatory physiology","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.1152/ajpheart.90085.2026","doi":"https://doi.org/10.1152/ajpheart.90085.2026","is_oa":true,"landing_page_url":"https://doi.org/10.1152/ajpheart.90085.2026","pdf_url":null,"source":{"id":"https://openalex.org/S87338489","display_name":"American Journal of Physiology-Heart and Circulatory Physiology","issn_l":"0363-6135","issn":["0363-6135","1522-1539"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-a","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320261","host_organization_name":"American Physical Society","host_organization_lineage":["https://openalex.org/P4310320261"],"host_organization_lineage_names":["American Physical Society"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"American Journal of Physiology-Heart and Circulatory Physiology","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.979200005531311}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320337338","display_name":"National Heart, Lung, and Blood Institute","ror":"https://ror.org/012pb6c26"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":75,"referenced_works":["https://openalex.org/W163997156","https://openalex.org/W1558810642","https://openalex.org/W1850582709","https://openalex.org/W1953327177","https://openalex.org/W1954294349","https://openalex.org/W1956526639","https://openalex.org/W1968072950","https://openalex.org/W1975654814","https://openalex.org/W1985399016","https://openalex.org/W2018366399","https://openalex.org/W2020868445","https://openalex.org/W2040159339","https://openalex.org/W2043659929","https://openalex.org/W2045888765","https://openalex.org/W2057131420","https://openalex.org/W2057365509","https://openalex.org/W2061278204","https://openalex.org/W2077244492","https://openalex.org/W2078653194","https://openalex.org/W2078702640","https://openalex.org/W2090721334","https://openalex.org/W2093798318","https://openalex.org/W2097830293","https://openalex.org/W2110076941","https://openalex.org/W2111857958","https://openalex.org/W2113686362","https://openalex.org/W2122648697","https://openalex.org/W2128925208","https://openalex.org/W2128986918","https://openalex.org/W2133845866","https://openalex.org/W2150396523","https://openalex.org/W2158374290","https://openalex.org/W2170417182","https://openalex.org/W2184794742","https://openalex.org/W2267534767","https://openalex.org/W2537881633","https://openalex.org/W2601591567","https://openalex.org/W2610746418","https://openalex.org/W2614280800","https://openalex.org/W2614924495","https://openalex.org/W2682020735","https://openalex.org/W2756082575","https://openalex.org/W2763829738","https://openalex.org/W2807637161","https://openalex.org/W2808313808","https://openalex.org/W2887865548","https://openalex.org/W2903873335","https://openalex.org/W2909042712","https://openalex.org/W2917793655","https://openalex.org/W2940625026","https://openalex.org/W2964856589","https://openalex.org/W2971328455","https://openalex.org/W2997147418","https://openalex.org/W3011466961","https://openalex.org/W3048944834","https://openalex.org/W3086065874","https://openalex.org/W3088459900","https://openalex.org/W3092984751","https://openalex.org/W3095680891","https://openalex.org/W3119399564","https://openalex.org/W3135720498","https://openalex.org/W3139478356","https://openalex.org/W3183126524","https://openalex.org/W3214335234","https://openalex.org/W4224883705","https://openalex.org/W4293037809","https://openalex.org/W4322758712","https://openalex.org/W4328053201","https://openalex.org/W4389225893","https://openalex.org/W4398767005","https://openalex.org/W4399366051","https://openalex.org/W4399862273","https://openalex.org/W4402490871","https://openalex.org/W4403485168","https://openalex.org/W4415549914"],"related_works":["https://openalex.org/W7160930286","https://openalex.org/W2313739180","https://openalex.org/W7096794260","https://openalex.org/W2101647334","https://openalex.org/W7098164368","https://openalex.org/W7154778720","https://openalex.org/W4398165438","https://openalex.org/W2058504608","https://openalex.org/W2118079678","https://openalex.org/W7018038271"],"abstract_inverted_index":{"Acute":[0],"consumption":[1],"of":[2,53,62],"a":[3,12],"long-chain":[4,35],"fatty":[5,36],"acid-rich":[6,37],"meal":[7],"increased":[8],"circulating":[9],"ceramides":[10],"in":[11,19,23],"sex-specific":[13],"manner,":[14],"with":[15,39],"elevations":[16],"observed":[17,42],"only":[18],"females.":[20],"Despite":[21],"this,":[22],"vivo":[24],"microvascular":[25,55],"endothelial":[26],"function":[27],"was":[28],"similarly":[29],"impaired":[30],"after":[31],"both":[32],"medium-":[33],"and":[34,57],"meals,":[38],"no":[40],"differences":[41],"between":[43],"sexes.":[44],"Further":[45],"studies":[46],"are":[47],"needed":[48],"to":[49],"define":[50],"the":[51,58],"role":[52],"ceramide-induced":[54],"dysfunction":[56],"long-term":[59],"cardiovascular":[60],"impact":[61],"repeated":[63],"exposure.":[64]},"counts_by_year":[],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2026-10-27T00:00:00"}