{"id":"https://openalex.org/W7223695243","doi":"https://doi.org/10.1093/eurpub/ckag169.950","title":"Extreme temperature events and multiple sclerosis relapses: evidence from France","display_name":"Extreme temperature events and multiple sclerosis relapses: evidence from France","publication_year":2026,"publication_date":"2026-10-01","ids":{"openalex":"https://openalex.org/W7223695243","doi":"https://doi.org/10.1093/eurpub/ckag169.950"},"language":"en","primary_location":{"id":"doi:10.1093/eurpub/ckag169.950","doi":"https://doi.org/10.1093/eurpub/ckag169.950","is_oa":true,"landing_page_url":"https://doi.org/10.1093/eurpub/ckag169.950","pdf_url":"https://academic.oup.com/eurpub/article-pdf/36/Supplement_5/ckag169.950/72465886/ckag169.950.pdf","source":{"id":"https://openalex.org/S4210220588","display_name":"European Journal of Public Health","issn_l":"1101-1262","issn":["1101-1262","1464-360X"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["abdc-b","anvur-class-a","anvur-scientific","cwts-core","doaj","dongbi-b","doyens","fnege-4","jufo-2","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"European Journal of Public Health","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://academic.oup.com/eurpub/article-pdf/36/Supplement_5/ckag169.950/72465886/ckag169.950.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5159651968","display_name":"G Fancello","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I39804081","display_name":"Sorbonne Universit\u00e9","ror":"https://ror.org/02en5vm52","country_code":"FR","type":"education","lineage":["https://openalex.org/I39804081"]},{"id":"https://openalex.org/I4210133907","display_name":"Institut Pierre Louis d\u2018\u00c9pid\u00e9miologie et de Sant\u00e9 Publique","ror":"https://ror.org/02qqh1125","country_code":"FR","type":"facility","lineage":["https://openalex.org/I154526488","https://openalex.org/I39804081","https://openalex.org/I4210133907"]}],"countries":["FR"],"is_corresponding":true,"raw_author_name":"G Fancello","raw_affiliation_strings":["Institut Pierre Louis d\u2019Epid\u00e9miologie et de Sant\u00e9 Publique, Equipe Nemesis, Sorbonne Universit\u00e9, INSERM , Paris,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institut Pierre Louis d\u2019Epid\u00e9miologie et de Sant\u00e9 Publique, Equipe Nemesis, Sorbonne Universit\u00e9, INSERM , Paris,","institution_ids":["https://openalex.org/I154526488","https://openalex.org/I39804081","https://openalex.org/I4210133907"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5159610369","display_name":"E Januel","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I39804081","display_name":"Sorbonne Universit\u00e9","ror":"https://ror.org/02en5vm52","country_code":"FR","type":"education","lineage":["https://openalex.org/I39804081"]},{"id":"https://openalex.org/I4210090185","display_name":"H\u00f4pital Rothschild","ror":"https://ror.org/009kb8w74","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210090185","https://openalex.org/I4210097159"]},{"id":"https://openalex.org/I4210097159","display_name":"Assistance Publique \u2013 H\u00f4pitaux de Paris","ror":"https://ror.org/00pg5jh14","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210097159"]},{"id":"https://openalex.org/I4210127304","display_name":"Fondation de Rothschild","ror":"https://ror.org/02yfw7119","country_code":"FR","type":"nonprofit","lineage":["https://openalex.org/I4210127304"]},{"id":"https://openalex.org/I4210133907","display_name":"Institut Pierre Louis d\u2018\u00c9pid\u00e9miologie et de Sant\u00e9 Publique","ror":"https://ror.org/02qqh1125","country_code":"FR","type":"facility","lineage":["https://openalex.org/I154526488","https://openalex.org/I39804081","https://openalex.org/I4210133907"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"E Januel","raw_affiliation_strings":["Institut Pierre Louis d\u2019Epid\u00e9miologie et de Sant\u00e9 Publique, Equipe PEPITES, AP-HP, Sorbonne Universit\u00e9, INSERM , Paris,","Neurology Department and Clinical Research Unit, H\u00f4pital Fondation A. de Rothschild , Paris,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institut Pierre Louis d\u2019Epid\u00e9miologie et de Sant\u00e9 Publique, Equipe PEPITES, AP-HP, Sorbonne Universit\u00e9, INSERM , Paris,","institution_ids":["https://openalex.org/I154526488","https://openalex.org/I39804081","https://openalex.org/I4210097159","https://openalex.org/I4210133907"]},{"raw_affiliation_string":"Neurology Department and Clinical Research Unit, H\u00f4pital Fondation A. de Rothschild , Paris,","institution_ids":["https://openalex.org/I4210090185","https://openalex.org/I4210127304"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5159650599","display_name":"J Hildago","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210136880","display_name":"Laboratoire Interdisciplinaire Solidarit\u00e9s Soci\u00e9t\u00e9s Territoires","ror":"https://ror.org/04m5rvb18","country_code":"FR","type":"facility","lineage":["https://openalex.org/I1294671590","https://openalex.org/I4210126056","https://openalex.org/I4210128193","https://openalex.org/I4210136880","https://openalex.org/I4210152422","https://openalex.org/I90669466"]},{"id":"https://openalex.org/I4405258862","display_name":"Universit\u00e9 de Toulouse","ror":"https://ror.org/01ahyrz84","country_code":"FR","type":"education","lineage":["https://openalex.org/I4405258862"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"J Hildago","raw_affiliation_strings":["Laboratoire Interdisciplinaire Solidarit\u00e9s Soci\u00e9t\u00e9s Territoires (LISST), CNR, Universit\u00e9 de Toulouse , Toulouse,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratoire Interdisciplinaire Solidarit\u00e9s Soci\u00e9t\u00e9s Territoires (LISST), CNR, Universit\u00e9 de Toulouse , Toulouse,","institution_ids":["https://openalex.org/I4210136880","https://openalex.org/I4405258862"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5159599756","display_name":"A M Vicedo-Cabrera","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I118564535","display_name":"University of Bern","ror":"https://ror.org/02k7v4d05","country_code":"CH","type":"education","lineage":["https://openalex.org/I118564535"]},{"id":"https://openalex.org/I1299204452","display_name":"Oeschger Centre for Climate Change Research","ror":"https://ror.org/0329s8h62","country_code":"CH","type":"facility","lineage":["https://openalex.org/I1299204452"]},{"id":"https://openalex.org/I4210135124","display_name":"Institute of Social and Preventive Medicine","ror":"https://ror.org/038esz880","country_code":"CH","type":"facility","lineage":["https://openalex.org/I2802229882","https://openalex.org/I4210135124","https://openalex.org/I4210149340","https://openalex.org/I97565354"]}],"countries":["CH"],"is_corresponding":false,"raw_author_name":"A M Vicedo-Cabrera","raw_affiliation_strings":["Institute of Social and Preventive Medicine and Oeschger Center for Climate Change Research, University of Bern , Bern,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Social and Preventive Medicine and Oeschger Center for Climate Change Research, University of Bern , Bern,","institution_ids":["https://openalex.org/I118564535","https://openalex.org/I1299204452","https://openalex.org/I4210135124"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5159725931","display_name":"P Masselot","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210089966","display_name":"London School of Hygiene & Tropical Medicine","ror":"https://ror.org/00a0jsq62","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I4210089966"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"P Masselot","raw_affiliation_strings":["LSHTM, Public Health and Policy , London,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"LSHTM, Public Health and Policy , London,","institution_ids":["https://openalex.org/I4210089966"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5159635564","display_name":"V Masson","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1294671590","display_name":"Centre National de la Recherche Scientifique","ror":"https://ror.org/02feahw73","country_code":"FR","type":"government","lineage":["https://openalex.org/I1294671590"]},{"id":"https://openalex.org/I4210088553","display_name":"Centre National de Recherches M\u00e9t\u00e9orologiques","ror":"https://ror.org/004rej139","country_code":"FR","type":"facility","lineage":["https://openalex.org/I1294671590","https://openalex.org/I4210088553","https://openalex.org/I4210113730","https://openalex.org/I4210148025"]},{"id":"https://openalex.org/I4210113730","display_name":"M\u00e9t\u00e9o-France","ror":"https://ror.org/0233st365","country_code":"FR","type":"other","lineage":["https://openalex.org/I4210113730"]},{"id":"https://openalex.org/I4405258862","display_name":"Universit\u00e9 de Toulouse","ror":"https://ror.org/01ahyrz84","country_code":"FR","type":"education","lineage":["https://openalex.org/I4405258862"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"V Masson","raw_affiliation_strings":["CNRM, M\u00e9t\u00e9o-France, CNRS, Universit\u00e9 de Toulouse , Toulouse,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"CNRM, M\u00e9t\u00e9o-France, CNRS, Universit\u00e9 de Toulouse , Toulouse,","institution_ids":["https://openalex.org/I1294671590","https://openalex.org/I4210088553","https://openalex.org/I4210113730","https://openalex.org/I4405258862"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5159582053","display_name":"C Morlighem","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I39804081","display_name":"Sorbonne Universit\u00e9","ror":"https://ror.org/02en5vm52","country_code":"FR","type":"education","lineage":["https://openalex.org/I39804081"]},{"id":"https://openalex.org/I4210133907","display_name":"Institut Pierre Louis d\u2018\u00c9pid\u00e9miologie et de Sant\u00e9 Publique","ror":"https://ror.org/02qqh1125","country_code":"FR","type":"facility","lineage":["https://openalex.org/I154526488","https://openalex.org/I39804081","https://openalex.org/I4210133907"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"C Morlighem","raw_affiliation_strings":["Institut Pierre Louis d\u2019Epid\u00e9miologie et de Sant\u00e9 Publique, Equipe Nemesis, Sorbonne Universit\u00e9, INSERM , Paris,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institut Pierre Louis d\u2019Epid\u00e9miologie et de Sant\u00e9 Publique, Equipe Nemesis, Sorbonne Universit\u00e9, INSERM , Paris,","institution_ids":["https://openalex.org/I154526488","https://openalex.org/I39804081","https://openalex.org/I4210133907"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5159603519","display_name":"N Strzelewicz","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210136880","display_name":"Laboratoire Interdisciplinaire Solidarit\u00e9s Soci\u00e9t\u00e9s Territoires","ror":"https://ror.org/04m5rvb18","country_code":"FR","type":"facility","lineage":["https://openalex.org/I1294671590","https://openalex.org/I4210126056","https://openalex.org/I4210128193","https://openalex.org/I4210136880","https://openalex.org/I4210152422","https://openalex.org/I90669466"]},{"id":"https://openalex.org/I4405258862","display_name":"Universit\u00e9 de Toulouse","ror":"https://ror.org/01ahyrz84","country_code":"FR","type":"education","lineage":["https://openalex.org/I4405258862"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"N Strzelewicz","raw_affiliation_strings":["Laboratoire Interdisciplinaire Solidarit\u00e9s Soci\u00e9t\u00e9s Territoires (LISST), CNR, Universit\u00e9 de Toulouse , Toulouse,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratoire Interdisciplinaire Solidarit\u00e9s Soci\u00e9t\u00e9s Territoires (LISST), CNR, Universit\u00e9 de Toulouse , Toulouse,","institution_ids":["https://openalex.org/I4210136880","https://openalex.org/I4405258862"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5159663262","display_name":"F Tubach","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I39804081","display_name":"Sorbonne Universit\u00e9","ror":"https://ror.org/02en5vm52","country_code":"FR","type":"education","lineage":["https://openalex.org/I39804081"]},{"id":"https://openalex.org/I4210097159","display_name":"Assistance Publique \u2013 H\u00f4pitaux de Paris","ror":"https://ror.org/00pg5jh14","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210097159"]},{"id":"https://openalex.org/I4210133907","display_name":"Institut Pierre Louis d\u2018\u00c9pid\u00e9miologie et de Sant\u00e9 Publique","ror":"https://ror.org/02qqh1125","country_code":"FR","type":"facility","lineage":["https://openalex.org/I154526488","https://openalex.org/I39804081","https://openalex.org/I4210133907"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"F Tubach","raw_affiliation_strings":["Institut Pierre Louis d\u2019Epid\u00e9miologie et de Sant\u00e9 Publique, Equipe PEPITES, AP-HP, Sorbonne Universit\u00e9, INSERM , Paris,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institut Pierre Louis d\u2019Epid\u00e9miologie et de Sant\u00e9 Publique, Equipe PEPITES, AP-HP, Sorbonne Universit\u00e9, INSERM , Paris,","institution_ids":["https://openalex.org/I154526488","https://openalex.org/I39804081","https://openalex.org/I4210097159","https://openalex.org/I4210133907"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5159638184","display_name":"B Chaix","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I39804081","display_name":"Sorbonne Universit\u00e9","ror":"https://ror.org/02en5vm52","country_code":"FR","type":"education","lineage":["https://openalex.org/I39804081"]},{"id":"https://openalex.org/I4210133907","display_name":"Institut Pierre Louis d\u2018\u00c9pid\u00e9miologie et de Sant\u00e9 Publique","ror":"https://ror.org/02qqh1125","country_code":"FR","type":"facility","lineage":["https://openalex.org/I154526488","https://openalex.org/I39804081","https://openalex.org/I4210133907"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"B Chaix","raw_affiliation_strings":["Institut Pierre Louis d\u2019Epid\u00e9miologie et de Sant\u00e9 Publique, Equipe Nemesis, Sorbonne Universit\u00e9, INSERM , Paris,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institut Pierre Louis d\u2019Epid\u00e9miologie et de Sant\u00e9 Publique, Equipe Nemesis, Sorbonne Universit\u00e9, INSERM , Paris,","institution_ids":["https://openalex.org/I154526488","https://openalex.org/I39804081","https://openalex.org/I4210133907"]}]}],"institutions":[],"countries_distinct_count":3,"institutions_distinct_count":15,"corresponding_author_ids":["https://openalex.org/A5159651968"],"corresponding_institution_ids":["https://openalex.org/I154526488","https://openalex.org/I39804081","https://openalex.org/I4210133907"],"apc_list":{"value":2815,"currency":"EUR","value_usd":3181},"apc_paid":{"value":2815,"currency":"EUR","value_usd":3181},"fwci":0.0,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":{"value":0.76130945,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"36","issue":"Supplement_5","first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11244","display_name":"Climate Change and Health Impacts","score":0.9940999746322632,"subfield":{"id":"https://openalex.org/subfields/2307","display_name":"Health, Toxicology and Mutagenesis"},"field":{"id":"https://openalex.org/fields/23","display_name":"Environmental Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T11244","display_name":"Climate Change and Health Impacts","score":0.9940999746322632,"subfield":{"id":"https://openalex.org/subfields/2307","display_name":"Health, Toxicology and Mutagenesis"},"field":{"id":"https://openalex.org/fields/23","display_name":"Environmental Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10137","display_name":"Multiple Sclerosis Research Studies","score":0.005499999970197678,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Clinical Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T14393","display_name":"Health, Environment, Cognitive Aging","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2307","display_name":"Health, Toxicology and Mutagenesis"},"field":{"id":"https://openalex.org/fields/23","display_name":"Environmental Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/multiple-sclerosis","display_name":"multiple sclerosis","score":0.9890000224113464},{"id":"https://openalex.org/keywords/relapse","display_name":"relapse","score":0.703000009059906},{"id":"https://openalex.org/keywords/extreme-heat","display_name":"extreme heat","score":0.953000009059906},{"id":"https://openalex.org/keywords/heat-waves","display_name":"heat waves","score":0.9919999837875366},{"id":"https://openalex.org/keywords/cold-waves","display_name":"cold waves","score":0.9449999928474426},{"id":"https://openalex.org/keywords/temperature-exposure","display_name":"temperature exposure","score":0.6069999933242798},{"id":"https://openalex.org/keywords/climate-change","display_name":"climate change","score":0.8069999814033508},{"id":"https://openalex.org/keywords/disease-activity","display_name":"disease activity","score":0.4449999928474426},{"id":"https://openalex.org/keywords/lagged-effects","display_name":"lagged effects","score":0.421999990940094}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.7458999752998352},{"id":"https://openalex.org/C2780640218","wikidata":"https://www.wikidata.org/wiki/Q8277","display_name":"Multiple sclerosis","level":2,"score":0.7236999869346619},{"id":"https://openalex.org/C156957248","wikidata":"https://www.wikidata.org/wiki/Q1862216","display_name":"Odds ratio","level":2,"score":0.6366000175476074},{"id":"https://openalex.org/C107130276","wikidata":"https://www.wikidata.org/wiki/Q133805","display_name":"Epidemiology","level":2,"score":0.6014999747276306},{"id":"https://openalex.org/C151956035","wikidata":"https://www.wikidata.org/wiki/Q1132755","display_name":"Logistic regression","level":2,"score":0.5967000126838684},{"id":"https://openalex.org/C72563966","wikidata":"https://www.wikidata.org/wiki/Q1303415","display_name":"Cohort","level":2,"score":0.579200029373169},{"id":"https://openalex.org/C201903717","wikidata":"https://www.wikidata.org/wiki/Q1778788","display_name":"Cohort study","level":2,"score":0.43459999561309814},{"id":"https://openalex.org/C143095724","wikidata":"https://www.wikidata.org/wiki/Q515895","display_name":"Odds","level":3,"score":0.4185999929904938},{"id":"https://openalex.org/C2781156865","wikidata":"https://www.wikidata.org/wiki/Q827023","display_name":"Lesion","level":2,"score":0.3662000000476837},{"id":"https://openalex.org/C149923435","wikidata":"https://www.wikidata.org/wiki/Q37732","display_name":"Demography","level":1,"score":0.3635999858379364},{"id":"https://openalex.org/C2993190167","wikidata":"https://www.wikidata.org/wiki/Q215864","display_name":"Extreme heat","level":3,"score":0.36160001158714294},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.3587000072002411},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.3379000127315521},{"id":"https://openalex.org/C44249647","wikidata":"https://www.wikidata.org/wiki/Q208498","display_name":"Confidence interval","level":2,"score":0.3305000066757202},{"id":"https://openalex.org/C2779662715","wikidata":"https://www.wikidata.org/wiki/Q19596443","display_name":"Conditional logistic regression","level":3,"score":0.32839998602867126},{"id":"https://openalex.org/C187212893","wikidata":"https://www.wikidata.org/wiki/Q123028","display_name":"Pediatrics","level":1,"score":0.3102000057697296},{"id":"https://openalex.org/C100564792","wikidata":"https://www.wikidata.org/wiki/Q190259","display_name":"Thermoregulation","level":2,"score":0.30640000104904175},{"id":"https://openalex.org/C2779668873","wikidata":"https://www.wikidata.org/wiki/Q6693756","display_name":"Lower risk","level":3,"score":0.2768999934196472},{"id":"https://openalex.org/C205545832","wikidata":"https://www.wikidata.org/wiki/Q17156455","display_name":"Young adult","level":2,"score":0.26570001244544983},{"id":"https://openalex.org/C77350462","wikidata":"https://www.wikidata.org/wiki/Q1125472","display_name":"Confounding","level":2,"score":0.26460000872612},{"id":"https://openalex.org/C30036603","wikidata":"https://www.wikidata.org/wiki/Q17125150","display_name":"Severity of illness","level":2,"score":0.26350000500679016},{"id":"https://openalex.org/C159009313","wikidata":"https://www.wikidata.org/wiki/Q5283159","display_name":"Distributed lag","level":2,"score":0.26350000500679016},{"id":"https://openalex.org/C2781258859","wikidata":"https://www.wikidata.org/wiki/Q1060890","display_name":"Shivering","level":2,"score":0.2549000084400177},{"id":"https://openalex.org/C12174686","wikidata":"https://www.wikidata.org/wiki/Q1058438","display_name":"Risk assessment","level":2,"score":0.2515999972820282}],"mesh":[],"locations_count":2,"locations":[{"id":"doi:10.1093/eurpub/ckag169.950","doi":"https://doi.org/10.1093/eurpub/ckag169.950","is_oa":true,"landing_page_url":"https://doi.org/10.1093/eurpub/ckag169.950","pdf_url":"https://academic.oup.com/eurpub/article-pdf/36/Supplement_5/ckag169.950/72465886/ckag169.950.pdf","source":{"id":"https://openalex.org/S4210220588","display_name":"European Journal of Public Health","issn_l":"1101-1262","issn":["1101-1262","1464-360X"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["abdc-b","anvur-class-a","anvur-scientific","cwts-core","doaj","dongbi-b","doyens","fnege-4","jufo-2","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"European Journal of Public Health","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:13699432","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC13699432/","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC13699432/pdf/ckag169.950.pdf","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Eur J Public Health","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1093/eurpub/ckag169.950","doi":"https://doi.org/10.1093/eurpub/ckag169.950","is_oa":true,"landing_page_url":"https://doi.org/10.1093/eurpub/ckag169.950","pdf_url":"https://academic.oup.com/eurpub/article-pdf/36/Supplement_5/ckag169.950/72465886/ckag169.950.pdf","source":{"id":"https://openalex.org/S4210220588","display_name":"European Journal of Public Health","issn_l":"1101-1262","issn":["1101-1262","1464-360X"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["abdc-b","anvur-class-a","anvur-scientific","cwts-core","doaj","dongbi-b","doyens","fnege-4","jufo-2","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"European Journal of Public Health","raw_type":"journal-article"},"sustainable_development_goals":[{"score":1.0,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W7223695243.pdf","grobid_xml":"https://content.openalex.org/works/W7223695243.grobid-xml"},"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W1964725892","https://openalex.org/W7223695416","https://openalex.org/W2053019207","https://openalex.org/W3007277703","https://openalex.org/W2070829635","https://openalex.org/W3167802184","https://openalex.org/W4416074253","https://openalex.org/W2605850927","https://openalex.org/W2066793288","https://openalex.org/W3158415670"],"abstract_inverted_index":{"Abstract":[0],"Background":[1],"Multiple":[2],"sclerosis":[3],"(MS)":[4],"is":[5,18,54],"a":[6,25],"chronic":[7],"autoimmune":[8],"disease":[9],"that":[10,243],"affects":[11],"around":[12],"130000":[13],"people":[14],"in":[15,30,66,269,318],"France.":[16],"It":[17],"characterized":[19],"by":[20,106],"recurrent":[21],"relapses":[22,150],"corresponding":[23],"to":[24,40,157,199,219,265,283,314],"newly":[26],"formed":[27],"inflammatory":[28],"lesion":[29],"the":[31,67,100,119,126,205,224,229,237,253,270,288,296,302,319],"central":[32],"nervous":[33],"system.":[34],"Lesion":[35],"development":[36],"begins":[37],"several":[38,248],"weeks":[39,235,294],"months":[41],"before":[42],"clinical":[43,85,241,280],"manifestation.":[44],"While":[45],"extreme":[46,97,214,220,284],"temperatures":[47],"are":[48],"suspected":[49],"activate":[50],"relapses,":[51],"epidemiological":[52],"evidence":[53],"limited.":[55],"Methods":[56],"We":[57,116],"collected":[58],"data":[59],"from":[60,191],"1189":[61],"relapsing":[62],"MS":[63],"patients":[64,141],"included":[65],"French":[68],"CONFISEP":[69],"cohort":[70],"(2018-2021),":[71],"including":[72],"daily":[73,80],"mean":[74],"temperature":[75,98],"at":[76,143,162,186],"geolocated":[77],"residential":[78],"addresses,":[79],"occurrence":[81],"of":[82,96,102,131,136,160,226,272,290,321],"MS-relapse":[83],"and":[84,123,133,181,261,310],"characteristics.":[86],"An":[87],"individual-level":[88],"case-time":[89],"series":[90],"design":[91],"was":[92,104],"applied.":[93],"The":[94,174],"impact":[95,231],"on":[99],"risk":[101,175,225,289],"MS-relapses":[103],"quantified":[105],"conditional":[107],"logistic":[108],"regression":[109],"combined":[110],"with":[111,167,177,183,228,240,279],"distributed":[112],"lag":[113],"non-linear":[114],"models.":[115],"first":[117],"assessed":[118],"overall":[120],"temperature-relapse":[121],"association":[122],"then":[124],"explored":[125],"effect":[127],"across":[128],"17":[129],"definitions":[130,135],"heatwaves":[132,198],"15":[134],"cold":[137,215],"spells.":[138,216],"Results":[139],"573":[140],"experienced":[142],"least":[144],"one":[145],"relapse,":[146],"accounting":[147],"for":[148,213,255,304],"939":[149],"overall.":[151],"Temperatures":[152],"\u226530":[153],"\u00b0C":[154],"where":[155],"related":[156],"higher":[158],"odds":[159,184],"relapse":[161,291],"lags":[163,187],"between":[164],"19-24":[165],"days,":[166],"maximum":[168],"OR":[169],"1.23":[170],"(95%CI:":[171,193,201],"1.05,":[172],"1.43).":[173],"rose":[176],"increasing":[178],"heatwave":[179],"intensity":[180],"duration,":[182],"ratio":[185],"17-26":[188],"days":[189],"ranging":[190],"1.06":[192],"1.01,":[194,202],"1.13)":[195],"during":[196,204],"mild":[197],"1.39":[200],"1.94)":[203],"most":[206],"severe":[207],"events.":[208],"No":[209],"associations":[210],"were":[211],"observed":[212,232],"Conclusions":[217],"Exposure":[218],"heat":[221,285],"significantly":[222,286],"increases":[223,287],"MS-relapse,":[227],"greatest":[230],"approximately":[233,292],"three":[234,293],"after":[236,295],"event,":[238],"consistent":[239],"observations":[242],"lesions":[244],"develops":[245],"gradually":[246],"over":[247],"weeks.":[249],"These":[250,299],"findings":[251,300],"highlight":[252,301],"need":[254,303],"targeted":[256,305],"preventive":[257,306],"measures,":[258,307],"patient":[259,308],"guidance":[260,309],"public":[262,311],"health":[263,312],"policies":[264,313],"protect":[266,315],"vulnerable":[267,316],"populations":[268,317],"context":[271,320],"climate":[273,322],"change.":[274,323],"Key":[275],"messages":[276],"\u2022":[277,298],"Consistent":[278],"observations,":[281],"exposure":[282],"event.":[297]},"counts_by_year":[],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2026-10-27T00:00:00"}