{"id":"https://openalex.org/W7223683095","doi":"https://doi.org/10.1002/mnfr.70633","title":"Maternal Vitamin D Deficiency is Associated With Sex\u2010Dependent Alterations in Neurodevelopment\u2010Related Gene Expression, Particularly in the Hypothalamus","display_name":"Maternal Vitamin D Deficiency is Associated With Sex\u2010Dependent Alterations in Neurodevelopment\u2010Related Gene Expression, Particularly in the Hypothalamus","publication_year":2026,"publication_date":"2026-10-01","ids":{"openalex":"https://openalex.org/W7223683095","doi":"https://doi.org/10.1002/mnfr.70633","pmid":"https://pubmed.ncbi.nlm.nih.gov/42928981","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/13696975"},"language":"en","primary_location":{"id":"doi:10.1002/mnfr.70633","doi":"https://doi.org/10.1002/mnfr.70633","is_oa":true,"landing_page_url":"https://doi.org/10.1002/mnfr.70633","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/mnfr.70633","source":{"id":"https://openalex.org/S27638457","display_name":"Molecular Nutrition & Food Research","issn_l":"1613-4125","issn":["1613-4125","1613-4133"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","jufo-3","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Molecular Nutrition & Food Research","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/mnfr.70633","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5092059962","display_name":"Lidia Saidi","orcid":"https://orcid.org/0000-0003-2051-0860","observed_orcids":["https://orcid.org/0000-0003-2051-0860"]},"institutions":[{"id":"https://openalex.org/I137407579","display_name":"Universit\u00e9 Oran 1 Ahmed Ben Bella","ror":"https://ror.org/059et2b68","country_code":"DZ","type":"education","lineage":["https://openalex.org/I137407579"]},{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I21491767","display_name":"Aix-Marseille Universit\u00e9","ror":"https://ror.org/035xkbk20","country_code":"FR","type":"education","lineage":["https://openalex.org/I21491767"]},{"id":"https://openalex.org/I4210088668","display_name":"Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement","ror":"https://ror.org/003vg9w96","country_code":"FR","type":"government","lineage":["https://openalex.org/I4210088668"]}],"countries":["DZ","FR"],"is_corresponding":false,"raw_author_name":"Lidia Saidi","raw_affiliation_strings":["Aix\u2010Marseille Univ INSERM INRAE C2VN  Marseille France","Laboratory of Physiology of Nutrition and Food, Safety Department of Biology Faculty of Natural and Life Sciences Oran 1 University  Oran Algeria"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Aix\u2010Marseille Univ INSERM INRAE C2VN  Marseille France","institution_ids":["https://openalex.org/I154526488","https://openalex.org/I21491767","https://openalex.org/I4210088668"]},{"raw_affiliation_string":"Laboratory of Physiology of Nutrition and Food, Safety Department of Biology Faculty of Natural and Life Sciences Oran 1 University  Oran Algeria","institution_ids":["https://openalex.org/I137407579"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5092774664","display_name":"Emmanuel Snacel-Fazy","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I21491767","display_name":"Aix-Marseille Universit\u00e9","ror":"https://ror.org/035xkbk20","country_code":"FR","type":"education","lineage":["https://openalex.org/I21491767"]},{"id":"https://openalex.org/I4210088668","display_name":"Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement","ror":"https://ror.org/003vg9w96","country_code":"FR","type":"government","lineage":["https://openalex.org/I4210088668"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Emmanuel Snacel\u2010Fazy","raw_affiliation_strings":["Aix\u2010Marseille Univ INSERM INRAE C2VN  Marseille France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Aix\u2010Marseille Univ INSERM INRAE C2VN  Marseille France","institution_ids":["https://openalex.org/I154526488","https://openalex.org/I21491767","https://openalex.org/I4210088668"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5159640697","display_name":"Eva Seipelt","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I21491767","display_name":"Aix-Marseille Universit\u00e9","ror":"https://ror.org/035xkbk20","country_code":"FR","type":"education","lineage":["https://openalex.org/I21491767"]},{"id":"https://openalex.org/I4210088668","display_name":"Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement","ror":"https://ror.org/003vg9w96","country_code":"FR","type":"government","lineage":["https://openalex.org/I4210088668"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Eva Seipelt","raw_affiliation_strings":["Aix\u2010Marseille Univ INSERM INRAE C2VN  Marseille France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Aix\u2010Marseille Univ INSERM INRAE C2VN  Marseille France","institution_ids":["https://openalex.org/I154526488","https://openalex.org/I21491767","https://openalex.org/I4210088668"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5059351388","display_name":"Nicole Haroun","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I21491767","display_name":"Aix-Marseille Universit\u00e9","ror":"https://ror.org/035xkbk20","country_code":"FR","type":"education","lineage":["https://openalex.org/I21491767"]},{"id":"https://openalex.org/I4210088668","display_name":"Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement","ror":"https://ror.org/003vg9w96","country_code":"FR","type":"government","lineage":["https://openalex.org/I4210088668"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Nicole Haroun","raw_affiliation_strings":["Aix\u2010Marseille Univ INSERM INRAE C2VN  Marseille France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Aix\u2010Marseille Univ INSERM INRAE C2VN  Marseille France","institution_ids":["https://openalex.org/I154526488","https://openalex.org/I21491767","https://openalex.org/I4210088668"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5106479282","display_name":"Julien Astier","orcid":"https://orcid.org/0009-0008-3281-7417","observed_orcids":["https://orcid.org/0009-0008-3281-7417"]},"institutions":[{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I21491767","display_name":"Aix-Marseille Universit\u00e9","ror":"https://ror.org/035xkbk20","country_code":"FR","type":"education","lineage":["https://openalex.org/I21491767"]},{"id":"https://openalex.org/I4210088668","display_name":"Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement","ror":"https://ror.org/003vg9w96","country_code":"FR","type":"government","lineage":["https://openalex.org/I4210088668"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Julien Astier","raw_affiliation_strings":["Aix\u2010Marseille Univ INSERM INRAE C2VN  Marseille France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Aix\u2010Marseille Univ INSERM INRAE C2VN  Marseille France","institution_ids":["https://openalex.org/I154526488","https://openalex.org/I21491767","https://openalex.org/I4210088668"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103281139","display_name":"Charl\u00e8ne Couturier","orcid":"https://orcid.org/0000-0001-8041-3961","observed_orcids":["https://orcid.org/0000-0001-8041-3961"]},"institutions":[{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I21491767","display_name":"Aix-Marseille Universit\u00e9","ror":"https://ror.org/035xkbk20","country_code":"FR","type":"education","lineage":["https://openalex.org/I21491767"]},{"id":"https://openalex.org/I4210088668","display_name":"Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement","ror":"https://ror.org/003vg9w96","country_code":"FR","type":"government","lineage":["https://openalex.org/I4210088668"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Charl\u00e8ne Couturier","raw_affiliation_strings":["Aix\u2010Marseille Univ INSERM INRAE C2VN  Marseille France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Aix\u2010Marseille Univ INSERM INRAE C2VN  Marseille France","institution_ids":["https://openalex.org/I154526488","https://openalex.org/I21491767","https://openalex.org/I4210088668"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5159669973","display_name":"Mohamed El Soltani","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I21491767","display_name":"Aix-Marseille Universit\u00e9","ror":"https://ror.org/035xkbk20","country_code":"FR","type":"education","lineage":["https://openalex.org/I21491767"]},{"id":"https://openalex.org/I4210088668","display_name":"Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement","ror":"https://ror.org/003vg9w96","country_code":"FR","type":"government","lineage":["https://openalex.org/I4210088668"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Mohamed El Soltani","raw_affiliation_strings":["Aix\u2010Marseille Univ INSERM INRAE C2VN  Marseille France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Aix\u2010Marseille Univ INSERM INRAE C2VN  Marseille France","institution_ids":["https://openalex.org/I154526488","https://openalex.org/I21491767","https://openalex.org/I4210088668"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5082544752","display_name":"Eric S\u00e9r\u00e9e","orcid":"https://orcid.org/0000-0003-2453-8393","observed_orcids":["https://orcid.org/0000-0003-2453-8393"]},"institutions":[{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I21491767","display_name":"Aix-Marseille Universit\u00e9","ror":"https://ror.org/035xkbk20","country_code":"FR","type":"education","lineage":["https://openalex.org/I21491767"]},{"id":"https://openalex.org/I4210088668","display_name":"Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement","ror":"https://ror.org/003vg9w96","country_code":"FR","type":"government","lineage":["https://openalex.org/I4210088668"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Eric S\u00e9r\u00e9e","raw_affiliation_strings":["Aix\u2010Marseille Univ INSERM INRAE C2VN  Marseille France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Aix\u2010Marseille Univ INSERM INRAE C2VN  Marseille France","institution_ids":["https://openalex.org/I154526488","https://openalex.org/I21491767","https://openalex.org/I4210088668"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5043495603","display_name":"Flavie Sicard","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I21491767","display_name":"Aix-Marseille Universit\u00e9","ror":"https://ror.org/035xkbk20","country_code":"FR","type":"education","lineage":["https://openalex.org/I21491767"]},{"id":"https://openalex.org/I4210088668","display_name":"Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement","ror":"https://ror.org/003vg9w96","country_code":"FR","type":"government","lineage":["https://openalex.org/I4210088668"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Flavie Sicard","raw_affiliation_strings":["Aix\u2010Marseille Univ INSERM INRAE C2VN  Marseille France","PhenoMARS Aix\u2010Marseille Technology Platform  Marseille France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Aix\u2010Marseille Univ INSERM INRAE C2VN  Marseille France","institution_ids":["https://openalex.org/I154526488","https://openalex.org/I21491767","https://openalex.org/I4210088668"]},{"raw_affiliation_string":"PhenoMARS Aix\u2010Marseille Technology Platform  Marseille France","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5056851959","display_name":"Habib Hammou","orcid":"https://orcid.org/0000-0003-2694-7430","observed_orcids":["https://orcid.org/0000-0003-2694-7430"]},"institutions":[{"id":"https://openalex.org/I137407579","display_name":"Universit\u00e9 Oran 1 Ahmed Ben Bella","ror":"https://ror.org/059et2b68","country_code":"DZ","type":"education","lineage":["https://openalex.org/I137407579"]}],"countries":["DZ"],"is_corresponding":false,"raw_author_name":"Habib Hammou","raw_affiliation_strings":["Laboratory of Physiology of Nutrition and Food, Safety Department of Biology Faculty of Natural and Life Sciences Oran 1 University  Oran Algeria"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory of Physiology of Nutrition and Food, Safety Department of Biology Faculty of Natural and Life Sciences Oran 1 University  Oran Algeria","institution_ids":["https://openalex.org/I137407579"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5159619628","display_name":"Michel Puceat","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I21491767","display_name":"Aix-Marseille Universit\u00e9","ror":"https://ror.org/035xkbk20","country_code":"FR","type":"education","lineage":["https://openalex.org/I21491767"]},{"id":"https://openalex.org/I4210088668","display_name":"Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement","ror":"https://ror.org/003vg9w96","country_code":"FR","type":"government","lineage":["https://openalex.org/I4210088668"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Michel Puceat","raw_affiliation_strings":["Aix\u2010Marseille Univ INSERM INRAE C2VN  Marseille France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Aix\u2010Marseille Univ INSERM INRAE C2VN  Marseille France","institution_ids":["https://openalex.org/I154526488","https://openalex.org/I21491767","https://openalex.org/I4210088668"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5005955072","display_name":"Jean\u2010Fran\u00e7ois Landrier","orcid":"https://orcid.org/0000-0002-8690-8014","observed_orcids":["https://orcid.org/0000-0002-8690-8014"]},"institutions":[{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I21491767","display_name":"Aix-Marseille Universit\u00e9","ror":"https://ror.org/035xkbk20","country_code":"FR","type":"education","lineage":["https://openalex.org/I21491767"]},{"id":"https://openalex.org/I4210088668","display_name":"Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement","ror":"https://ror.org/003vg9w96","country_code":"FR","type":"government","lineage":["https://openalex.org/I4210088668"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Jean\u2010Fran\u00e7ois Landrier","raw_affiliation_strings":["Aix\u2010Marseille Univ INSERM INRAE C2VN  Marseille France","PhenoMARS Aix\u2010Marseille Technology Platform  Marseille France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Aix\u2010Marseille Univ INSERM INRAE C2VN  Marseille France","institution_ids":["https://openalex.org/I154526488","https://openalex.org/I21491767","https://openalex.org/I4210088668"]},{"raw_affiliation_string":"PhenoMARS Aix\u2010Marseille Technology Platform  Marseille France","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5003795666","display_name":"Lourdes Mounien","orcid":"https://orcid.org/0000-0002-9221-5783","observed_orcids":["https://orcid.org/0000-0002-9221-5783"]},"institutions":[{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I21491767","display_name":"Aix-Marseille Universit\u00e9","ror":"https://ror.org/035xkbk20","country_code":"FR","type":"education","lineage":["https://openalex.org/I21491767"]},{"id":"https://openalex.org/I4210088668","display_name":"Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement","ror":"https://ror.org/003vg9w96","country_code":"FR","type":"government","lineage":["https://openalex.org/I4210088668"]}],"countries":["FR"],"is_corresponding":true,"raw_author_name":"Lourdes Mounien","raw_affiliation_strings":["Aix\u2010Marseille Univ INSERM INRAE C2VN  Marseille France","PhenoMARS Aix\u2010Marseille Technology Platform  Marseille France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Aix\u2010Marseille Univ INSERM INRAE C2VN  Marseille France","institution_ids":["https://openalex.org/I154526488","https://openalex.org/I21491767","https://openalex.org/I4210088668"]},{"raw_affiliation_string":"PhenoMARS Aix\u2010Marseille Technology Platform  Marseille France","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5003795666"],"corresponding_institution_ids":["https://openalex.org/I154526488","https://openalex.org/I21491767","https://openalex.org/I4210088668"],"apc_list":{"value":4880,"currency":"USD","value_usd":4880},"apc_paid":{"value":4880,"currency":"USD","value_usd":4880},"fwci":0.0,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":{"value":0.82889683,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"70","issue":"20","first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10277","display_name":"Vitamin D Research Studies","score":0.9833999872207642,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10277","display_name":"Vitamin D Research Studies","score":0.9833999872207642,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11629","display_name":"Birth, Development, and Health","score":0.008999999612569809,"subfield":{"id":"https://openalex.org/subfields/2735","display_name":"Pediatrics, Perinatology and Child Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10608","display_name":"Neurogenesis and neuroplasticity mechanisms","score":0.002099999925121665,"subfield":{"id":"https://openalex.org/subfields/2806","display_name":"Developmental Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/maternal-vitamin-d-deficiency","display_name":"maternal vitamin D deficiency","score":0.9950000047683716},{"id":"https://openalex.org/keywords/hypothalamus","display_name":"hypothalamus","score":0.8119999766349792},{"id":"https://openalex.org/keywords/sex-differences","display_name":"sex differences","score":0.7699999809265137},{"id":"https://openalex.org/keywords/brain-development","display_name":"brain development","score":0.9100000262260437},{"id":"https://openalex.org/keywords/gene-expression","display_name":"gene expression","score":0.7279999852180481},{"id":"https://openalex.org/keywords/neuronal-differentiation","display_name":"neuronal differentiation","score":0.9089999794960022},{"id":"https://openalex.org/keywords/synaptogenesis","display_name":"synaptogenesis","score":0.9829999804496765},{"id":"https://openalex.org/keywords/astrocytes","display_name":"astrocytes","score":0.9210000038146973},{"id":"https://openalex.org/keywords/melanocortin-pathway","display_name":"melanocortin pathway","score":0.9879999756813049},{"id":"https://openalex.org/keywords/synaptic-signaling","display_name":"synaptic signaling","score":0.9959999918937683},{"id":"https://openalex.org/keywords/postnatal-brain-development","display_name":"postnatal brain development","score":0.7020000219345093}],"concepts":[{"id":"https://openalex.org/C65232495","wikidata":"https://www.wikidata.org/wiki/Q1813773","display_name":"Synaptogenesis","level":2,"score":0.8752999901771545},{"id":"https://openalex.org/C112672928","wikidata":"https://www.wikidata.org/wiki/Q239526","display_name":"Offspring","level":3,"score":0.7635999917984009},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.7207000255584717},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.7125999927520752},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.6879000067710876},{"id":"https://openalex.org/C162317418","wikidata":"https://www.wikidata.org/wiki/Q252857","display_name":"Transcriptome","level":4,"score":0.6453999876976013},{"id":"https://openalex.org/C150194340","wikidata":"https://www.wikidata.org/wiki/Q26972","display_name":"Gene expression","level":3,"score":0.6312000155448914},{"id":"https://openalex.org/C2777003273","wikidata":"https://www.wikidata.org/wiki/Q164386","display_name":"Hypothalamus","level":2,"score":0.6240000128746033},{"id":"https://openalex.org/C124490489","wikidata":"https://www.wikidata.org/wiki/Q7936963","display_name":"Vitamin D and neurology","level":2,"score":0.46720001101493835},{"id":"https://openalex.org/C2779740938","wikidata":"https://www.wikidata.org/wiki/Q4138762","display_name":"vitamin D deficiency","level":3,"score":0.45680001378059387},{"id":"https://openalex.org/C165864922","wikidata":"https://www.wikidata.org/wiki/Q411391","display_name":"Regulation of gene expression","level":3,"score":0.3874000012874603},{"id":"https://openalex.org/C63645605","wikidata":"https://www.wikidata.org/wiki/Q103191","display_name":"Homeostasis","level":2,"score":0.3619999885559082},{"id":"https://openalex.org/C105580179","wikidata":"https://www.wikidata.org/wiki/Q188928","display_name":"Messenger RNA","level":3,"score":0.3231000006198883},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.3100999891757965},{"id":"https://openalex.org/C2779555244","wikidata":"https://www.wikidata.org/wiki/Q409638","display_name":"Immediate early gene","level":4,"score":0.3012999892234802},{"id":"https://openalex.org/C4746552","wikidata":"https://www.wikidata.org/wiki/Q1456827","display_name":"Neurogenesis","level":2,"score":0.2515999972820282},{"id":"https://openalex.org/C18431079","wikidata":"https://www.wikidata.org/wiki/Q1502169","display_name":"Gene expression profiling","level":4,"score":0.25099998712539673}],"mesh":[{"descriptor_ui":"D000099203","descriptor_name":"Neurodevelopment","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007031","descriptor_name":"Hypothalamus","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008810","descriptor_name":"Mice, Inbred C57BL","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011247","descriptor_name":"Pregnancy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012333","descriptor_name":"RNA, Messenger","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D012737","descriptor_name":"Sex Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014808","descriptor_name":"Vitamin D Deficiency","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D039382","descriptor_name":"Maternal Nutritional Physiological Phenomena","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1002/mnfr.70633","doi":"https://doi.org/10.1002/mnfr.70633","is_oa":true,"landing_page_url":"https://doi.org/10.1002/mnfr.70633","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/mnfr.70633","source":{"id":"https://openalex.org/S27638457","display_name":"Molecular Nutrition & Food Research","issn_l":"1613-4125","issn":["1613-4125","1613-4133"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","jufo-3","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Molecular Nutrition & Food Research","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:13696975","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC13696975/","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC13696975/pdf/MNFR-70-e70633.pdf","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Mol Nutr Food Res","raw_type":"Text"},{"id":"pmid:42928981","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/42928981","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Molecular nutrition & food research","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.1002/mnfr.70633","doi":"https://doi.org/10.1002/mnfr.70633","is_oa":true,"landing_page_url":"https://doi.org/10.1002/mnfr.70633","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/mnfr.70633","source":{"id":"https://openalex.org/S27638457","display_name":"Molecular Nutrition & Food Research","issn_l":"1613-4125","issn":["1613-4125","1613-4133"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","jufo-3","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Molecular Nutrition & Food Research","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.9391000270843506,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W7223683095.pdf","grobid_xml":"https://content.openalex.org/works/W7223683095.grobid-xml"},"referenced_works_count":38,"referenced_works":["https://openalex.org/W1893024994","https://openalex.org/W1968454615","https://openalex.org/W1974173211","https://openalex.org/W1982145294","https://openalex.org/W1992187858","https://openalex.org/W1994956074","https://openalex.org/W1995878014","https://openalex.org/W1996853027","https://openalex.org/W2000253046","https://openalex.org/W2008359796","https://openalex.org/W2010541258","https://openalex.org/W2021788127","https://openalex.org/W2032288122","https://openalex.org/W2033616801","https://openalex.org/W2042916372","https://openalex.org/W2077251596","https://openalex.org/W2096407616","https://openalex.org/W2100057436","https://openalex.org/W2101292935","https://openalex.org/W2111598959","https://openalex.org/W2124064773","https://openalex.org/W2153784703","https://openalex.org/W2223173753","https://openalex.org/W2347173394","https://openalex.org/W2404128804","https://openalex.org/W2790148108","https://openalex.org/W2979406738","https://openalex.org/W2996505549","https://openalex.org/W3085119287","https://openalex.org/W3106618836","https://openalex.org/W3113912473","https://openalex.org/W4226146295","https://openalex.org/W4280628349","https://openalex.org/W4283460371","https://openalex.org/W4378905064","https://openalex.org/W4382984627","https://openalex.org/W4389069267","https://openalex.org/W4406924895"],"related_works":["https://openalex.org/W2008359796","https://openalex.org/W1996186369","https://openalex.org/W2223173753","https://openalex.org/W2790148108","https://openalex.org/W4224937900","https://openalex.org/W2034256696","https://openalex.org/W7150896341","https://openalex.org/W3113048898","https://openalex.org/W4378905064","https://openalex.org/W2462935756"],"abstract_inverted_index":{"Vitamin":[0],"D":[1],"(VD)":[2],"is":[3],"essential":[4],"for":[5,13],"calcium":[6],"homeostasis":[7],"and":[8,16,55,58,78,102,112,140,155,193],"bone":[9],"metabolism":[10],"but":[11],"also":[12],"brain":[14,33,52,128],"development":[15],"function.":[17],"However,":[18],"few":[19],"data":[20],"are":[21],"available":[22],"on":[23,31,50],"the":[24,45,107],"impact":[25,46],"of":[26,47,72,86,100,109,134,153,163],"maternal":[27,48,168,174],"VD":[28],"deficiency":[29],"(VDD)":[30],"sex-specific":[32],"development,":[34,53,129],"particularly":[35],"in":[36,62,80,106,122,137,142,189],"specific":[37],"structures":[38],"such":[39],"as":[40],"hypothalamus.":[41],"This":[42],"study":[43],"investigated":[44],"VDD":[49,65,116,175],"early":[51,110,127,182],"neuronal":[54,76,138],"glial":[56],"differentiation,":[57],"hypothalamic":[59,164],"gene":[60,123,165,179],"expression":[61,71,85,124,133,152,166,180],"mice.":[63,114],"Maternal":[64,115],"was":[66,117],"associated":[67,118],"with":[68,119,130],"increased":[69],"mRNA":[70,84,132],"markers":[73,88,135],"related":[74],"to":[75,126,167,186],"differentiation":[77,139],"synaptogenesis":[79,141],"both":[81,143],"sexes,":[82],"while":[83],"astrocyte-related":[87],"remained":[89],"largely":[90],"unchanged.":[91],"Male":[92,145],"offspring":[93,146],"exhibited":[94,147],"broader":[95],"transcriptomic":[96,148],"alterations,":[97],"including":[98,150],"dysregulation":[99],"melanocortin-pathway":[101,154],"synaptic":[103,156,190],"signaling":[104,157],"genes,":[105,158],"hypothalamus":[108],"postnatal":[111],"adult":[113],"sex-dependent":[120],"changes":[121],"relevant":[125],"altered":[131,151],"involved":[136],"sexes.":[144],"changes,":[149],"further":[159],"suggesting":[160],"greater":[161],"susceptibility":[162],"VDD.":[169],"These":[170],"findings":[171],"indicate":[172],"that":[173],"may":[176],"influence":[177],"neurodevelopmental":[178],"during":[181],"life,":[183],"potentially":[184],"contributing":[185],"later":[187],"alterations":[188],"function,":[191],"metabolism,":[192],"behavior.":[194]},"counts_by_year":[],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2026-10-27T00:00:00"}