{"id":"https://openalex.org/W7223675308","doi":"https://doi.org/10.7759/cureus.118639","title":"The Changing Landscape of Splenectomy in Women at a UK University Teaching Hospital: The Role of Gynaecological Oncology","display_name":"The Changing Landscape of Splenectomy in Women at a UK University Teaching Hospital: The Role of Gynaecological Oncology","publication_year":2026,"publication_date":"2026-10-26","ids":{"openalex":"https://openalex.org/W7223675308","doi":"https://doi.org/10.7759/cureus.118639"},"language":"en","primary_location":{"id":"doi:10.7759/cureus.118639","doi":"https://doi.org/10.7759/cureus.118639","is_oa":true,"landing_page_url":"https://doi.org/10.7759/cureus.118639","pdf_url":"https://www.cureus.com/articles/543233-the-changing-landscape-of-splenectomy-in-women-at-a-uk-university-teaching-hospital-the-role-of-gynaecological-oncology.pdf","source":{"id":"https://openalex.org/S2738950867","display_name":"Cureus","issn_l":"2168-8184","issn":["2168-8184"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","poland-20","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310316779","host_organization_name":"Cureus, Inc.","host_organization_lineage":["https://openalex.org/P4310316779"],"host_organization_lineage_names":["Cureus, Inc."],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cureus","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"diamond","oa_url":"https://www.cureus.com/articles/543233-the-changing-landscape-of-splenectomy-in-women-at-a-uk-university-teaching-hospital-the-role-of-gynaecological-oncology.pdf","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5120708274","display_name":"Mahwish Nayab","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210149821","display_name":"University Hospitals of Derby and Burton NHS Foundation Trust","ror":"https://ror.org/04w8sxm43","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I4210149821"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Mahwish Nayab","raw_affiliation_strings":[". Obstetrics and Gynaecology , Derby Gynaecological Cancer Centre , University Hospitals of Derby and Burton NHS Foundation Trust , Derby , GBR"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":". Obstetrics and Gynaecology , Derby Gynaecological Cancer Centre , University Hospitals of Derby and Burton NHS Foundation Trust , Derby , GBR","institution_ids":["https://openalex.org/I4210149821"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5159640025","display_name":"Safa Asghar","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210149821","display_name":"University Hospitals of Derby and Burton NHS Foundation Trust","ror":"https://ror.org/04w8sxm43","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I4210149821"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Safa Asghar","raw_affiliation_strings":[". Obstetrics and Gynaecology , Derby Gynaecological Cancer Centre , University Hospitals of Derby and Burton NHS Foundation Trust , Derby , GBR"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":". Obstetrics and Gynaecology , Derby Gynaecological Cancer Centre , University Hospitals of Derby and Burton NHS Foundation Trust , Derby , GBR","institution_ids":["https://openalex.org/I4210149821"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5077772875","display_name":"Viren Asher","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210149821","display_name":"University Hospitals of Derby and Burton NHS Foundation Trust","ror":"https://ror.org/04w8sxm43","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I4210149821"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Viren Asher","raw_affiliation_strings":[". Obstetrics and Gynaecology , Derby Gynaecological Cancer Centre , University Hospitals of Derby and Burton NHS Foundation Trust , Derby , GBR"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":". Obstetrics and Gynaecology , Derby Gynaecological Cancer Centre , University Hospitals of Derby and Burton NHS Foundation Trust , Derby , GBR","institution_ids":["https://openalex.org/I4210149821"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5089835925","display_name":"Susan Addley","orcid":"https://orcid.org/0000-0001-8272-8537","observed_orcids":["https://orcid.org/0000-0001-8272-8537"]},"institutions":[{"id":"https://openalex.org/I4210149821","display_name":"University Hospitals of Derby and Burton NHS Foundation Trust","ror":"https://ror.org/04w8sxm43","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I4210149821"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Susan Addley","raw_affiliation_strings":[". Obstetrics and Gynaecology , Derby Gynaecological Cancer Centre , University Hospitals of Derby and Burton NHS Foundation Trust , Derby , GBR"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":". Obstetrics and Gynaecology , Derby Gynaecological Cancer Centre , University Hospitals of Derby and Burton NHS Foundation Trust , Derby , GBR","institution_ids":["https://openalex.org/I4210149821"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111150283","display_name":"Summi Abdul","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I142263535","display_name":"University of Nottingham","ror":"https://ror.org/01ee9ar58","country_code":"GB","type":"education","lineage":["https://openalex.org/I142263535"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Summi Abdul","raw_affiliation_strings":[". Medicine and Surgery , University of Nottingham , Nottingham , GBR"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":". Medicine and Surgery , University of Nottingham , Nottingham , GBR","institution_ids":["https://openalex.org/I142263535"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5102716458","display_name":"Anish Bali","orcid":"https://orcid.org/0000-0003-1842-9043","observed_orcids":["https://orcid.org/0000-0003-1842-9043"]},"institutions":[{"id":"https://openalex.org/I142263535","display_name":"University of Nottingham","ror":"https://ror.org/01ee9ar58","country_code":"GB","type":"education","lineage":["https://openalex.org/I142263535"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Anish Bali","raw_affiliation_strings":[". Medicine and Surgery , University of Nottingham , Nottingham , GBR"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":". Medicine and Surgery , University of Nottingham , Nottingham , GBR","institution_ids":["https://openalex.org/I142263535"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5021925215","display_name":"Andrew Phillips","orcid":"https://orcid.org/0000-0003-0952-6810","observed_orcids":["https://orcid.org/0000-0003-0952-6810"]},"institutions":[{"id":"https://openalex.org/I4210149821","display_name":"University Hospitals of Derby and Burton NHS Foundation Trust","ror":"https://ror.org/04w8sxm43","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I4210149821"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Andrew Phillips","raw_affiliation_strings":[". Obstetrics and Gynaecology , Derby Gynaecological Cancer Centre , University Hospitals of Derby and Burton NHS Foundation Trust , Derby , GBR"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":". Obstetrics and Gynaecology , Derby Gynaecological Cancer Centre , University Hospitals of Derby and Burton NHS Foundation Trust , Derby , GBR","institution_ids":["https://openalex.org/I4210149821"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":{"value":0.87925049,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10550","display_name":"Ovarian cancer diagnosis and treatment","score":0.5419999957084656,"subfield":{"id":"https://openalex.org/subfields/2743","display_name":"Reproductive Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10550","display_name":"Ovarian cancer diagnosis and treatment","score":0.5419999957084656,"subfield":{"id":"https://openalex.org/subfields/2743","display_name":"Reproductive Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10668","display_name":"Endometrial and Cervical Cancer Treatments","score":0.08259999752044678,"subfield":{"id":"https://openalex.org/subfields/2729","display_name":"Obstetrics and Gynecology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10989","display_name":"Uterine Myomas and Treatments","score":0.06629999727010727,"subfield":{"id":"https://openalex.org/subfields/2729","display_name":"Obstetrics and Gynecology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/splenectomy","display_name":"splenectomy","score":0.9990000128746033},{"id":"https://openalex.org/keywords/women","display_name":"women","score":0.6840000152587891},{"id":"https://openalex.org/keywords/gynecologic-oncology","display_name":"gynecologic oncology","score":0.9900000095367432},{"id":"https://openalex.org/keywords/surgical-trends","display_name":"surgical trends","score":0.5170000195503235},{"id":"https://openalex.org/keywords/gynecologic-cancer","display_name":"gynecologic cancer","score":0.6159999966621399},{"id":"https://openalex.org/keywords/spleen","display_name":"spleen","score":0.4970000088214874}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9794999957084656},{"id":"https://openalex.org/C2776309230","wikidata":"https://www.wikidata.org/wiki/Q580383","display_name":"Splenectomy","level":3,"score":0.7831000089645386},{"id":"https://openalex.org/C61434518","wikidata":"https://www.wikidata.org/wiki/Q932510","display_name":"General surgery","level":1,"score":0.4950000047683716},{"id":"https://openalex.org/C512399662","wikidata":"https://www.wikidata.org/wiki/Q3505712","display_name":"Family medicine","level":1,"score":0.4065000116825104},{"id":"https://openalex.org/C29456083","wikidata":"https://www.wikidata.org/wiki/Q1221899","display_name":"Gynecology","level":1,"score":0.35420000553131104},{"id":"https://openalex.org/C2779473830","wikidata":"https://www.wikidata.org/wiki/Q1540899","display_name":"MEDLINE","level":2,"score":0.34769999980926514},{"id":"https://openalex.org/C2780435969","wikidata":"https://www.wikidata.org/wiki/Q5625186","display_name":"Gynecologic oncology","level":2,"score":0.26440000534057617},{"id":"https://openalex.org/C2776598537","wikidata":"https://www.wikidata.org/wiki/Q1812651","display_name":"Clinical Oncology","level":3,"score":0.25369998812675476},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.24289999902248383},{"id":"https://openalex.org/C159110408","wikidata":"https://www.wikidata.org/wiki/Q121176","display_name":"Nursing","level":1,"score":0.2240000069141388}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.7759/cureus.118639","doi":"https://doi.org/10.7759/cureus.118639","is_oa":true,"landing_page_url":"https://doi.org/10.7759/cureus.118639","pdf_url":"https://www.cureus.com/articles/543233-the-changing-landscape-of-splenectomy-in-women-at-a-uk-university-teaching-hospital-the-role-of-gynaecological-oncology.pdf","source":{"id":"https://openalex.org/S2738950867","display_name":"Cureus","issn_l":"2168-8184","issn":["2168-8184"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","poland-20","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310316779","host_organization_name":"Cureus, Inc.","host_organization_lineage":["https://openalex.org/P4310316779"],"host_organization_lineage_names":["Cureus, Inc."],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cureus","raw_type":"journal-article"}],"best_oa_location":{"id":"doi:10.7759/cureus.118639","doi":"https://doi.org/10.7759/cureus.118639","is_oa":true,"landing_page_url":"https://doi.org/10.7759/cureus.118639","pdf_url":"https://www.cureus.com/articles/543233-the-changing-landscape-of-splenectomy-in-women-at-a-uk-university-teaching-hospital-the-role-of-gynaecological-oncology.pdf","source":{"id":"https://openalex.org/S2738950867","display_name":"Cureus","issn_l":"2168-8184","issn":["2168-8184"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","poland-20","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310316779","host_organization_name":"Cureus, Inc.","host_organization_lineage":["https://openalex.org/P4310316779"],"host_organization_lineage_names":["Cureus, Inc."],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cureus","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.9763000011444092,"display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W7223675308.pdf","grobid_xml":"https://content.openalex.org/works/W7223675308.grobid-xml"},"referenced_works_count":19,"referenced_works":["https://openalex.org/W2017074869","https://openalex.org/W2018797399","https://openalex.org/W2020938727","https://openalex.org/W2082851035","https://openalex.org/W2153914851","https://openalex.org/W2164621050","https://openalex.org/W2307646495","https://openalex.org/W2317509465","https://openalex.org/W2907250455","https://openalex.org/W2971443530","https://openalex.org/W3022420474","https://openalex.org/W3086320969","https://openalex.org/W3115810660","https://openalex.org/W3168374360","https://openalex.org/W4206917927","https://openalex.org/W4394721833","https://openalex.org/W4399898754","https://openalex.org/W4404443717","https://openalex.org/W7118003472"],"related_works":["https://openalex.org/W2017074869","https://openalex.org/W2977540123","https://openalex.org/W2992609771","https://openalex.org/W4409905982","https://openalex.org/W2408933839","https://openalex.org/W2067858682","https://openalex.org/W4392633063","https://openalex.org/W1979473527","https://openalex.org/W4225102748","https://openalex.org/W2325543457"],"abstract_inverted_index":{"ObjectiveTo":[0],"characterise":[1],"the":[2,32,49,103],"volume,":[3],"indications":[4,197],"and":[5,25,29,54,78,88,93,107,132,141,161,172,184,196,281],"surgical":[6,26],"context":[7],"of":[8,34,41,52,158,175,190,206,234,278],"splenectomy":[9,47,260],"in":[10,90,204,261],"adult":[11],"women":[12,124],"at":[13,48,119],"a":[14,255],"UK":[15],"tertiary":[16],"centre,":[17],"comparing":[18],"gynaecological":[19],"oncology":[20],"(GO)":[21],"with":[22,99,177,245,267],"general":[23],"surgery":[24],"subspecialities":[27],"(GS),":[28],"to":[30,65,258],"examine":[31],"distribution":[33],"procedural":[35],"exposure":[36],"between":[37],"specialities.":[38],"MethodsRetrospective":[39],"study":[40],"all":[42,146,159,162],"female":[43],"patients":[44],"who":[45],"underwent":[46,125,129],"University":[50],"Hospitals":[51],"Derby":[53],"Burton":[55],"(UHDB)":[56],"NHS":[57],"Foundation":[58],"Trust,":[59],"Derby,":[60],"UK,":[61],"from":[62,84],"January":[63],"2014":[64],"June":[66],"2025.Exclusion":[67],"criteria":[68],"were":[69,82,96,149,166,193,198,230,250],"male":[70],"sex,":[71],"splenic":[72],"biopsy":[73],"only,":[74],"splenunculus":[75],"removal":[76],"only":[77],"age":[79],"<18":[80],"years.Data":[81],"extracted":[83],"electronic":[85],"patient":[86],"records":[87],"collated":[89],"Microsoft":[91],"Excel.Categorical":[92],"continuous":[94],"variables":[95],"summarised":[97],"descriptively,":[98],"Fisher's":[100],"exact":[101],"test,":[102],"Mann-Whitney":[104],"U":[105],"test":[106],"negative":[108],"binomial":[109],"regression":[110],"analyses":[111],"used":[112],"as":[113],"appropriate;":[114],"statistical":[115],"significance":[116],"was":[117,201,240],"set":[118],"p":[120],"<":[121],"0.05.":[122],"ResultsNinety-four":[123],"splenectomy;":[126],"69":[127],"(73.4%)":[128],"elective":[130,144,154,259],"procedures,":[131,155,195],"25":[133],"(26.6%)underwent":[134],"emergency":[135,163],"procedures.GO":[136],"performed":[137,151],"46/94":[138],"(49.0%)":[139],"procedures":[140,148,210,223],"46/69":[142],"(66.7%)":[143],"procedures;":[145],"GO":[147,207,243],"elective.GS":[150],"23/69":[152],"(33.3%)":[153],"48/94":[156],"(51.0%)":[157],"splenectomies":[160,165,192,235],"splenectomies.GO":[164],"undertaken":[167],"for":[168,211,224,242,247,275],"advanced":[169],"M\u00fcllerian":[170],"malignancy":[171],"formed":[173],"part":[174],"cytoreduction,":[176],"concomitant":[178],"omentectomy":[179],"(97.8%),":[180],"uterine/adnexal":[181],"resection":[182,186],"(84.8%)":[183],"colorectal":[185],"(60.9%).In":[187],"contrast,":[188],"79.2%":[189],"GS":[191,209,269],"isolated":[194],"heterogeneous.Malignant":[199],"involvement":[200],"confirmed":[202],"histologically":[203],"89.1%":[205],"splenectomies.Among":[208],"known":[212],"or":[213],"suspected":[214,225],"malignancy,":[215,227],"7/15":[216],"(46.7%)":[217],"had":[218],"malignant":[219],"involvement;":[220],"among":[221],"five":[222],"solid-organ":[226],"two":[228],"(40%)":[229],"confirmed.The":[231],"mean":[232],"number":[233],"per":[236,238],"surgeon":[237],"year":[239],"1.00":[241],"compared":[244],"0.23":[246],"GS.Temporal":[248],"trends":[249],"non-significant.":[251],"ConclusionGO":[252],"has":[253],"become":[254],"major":[256],"contributor":[257],"women.Its":[262],"concentrated":[263],"multivisceral":[264],"practice":[265],"contrasts":[266],"dispersed":[268],"exposure.These":[270],"findings":[271],"highlight":[272],"potential":[273],"opportunities":[274],"crossspeciality":[276],"discussion":[277],"operative":[279],"experience":[280],"training.":[282]},"counts_by_year":[],"updated_date":"2026-10-29T09:56:32.521200","created_date":"2026-10-27T00:00:00"}