{"id":"https://openalex.org/W7223663525","doi":"https://doi.org/10.1186/s12885-026-17203-8","title":"Clinical features and outcomes of orbital involvement in mantle cell lymphoma: a 15-year retrospective study and literature review","display_name":"Clinical features and outcomes of orbital involvement in mantle cell lymphoma: a 15-year retrospective study and literature review","publication_year":2026,"publication_date":"2026-10-26","ids":{"openalex":"https://openalex.org/W7223663525","doi":"https://doi.org/10.1186/s12885-026-17203-8"},"language":"en","primary_location":{"id":"doi:10.1186/s12885-026-17203-8","doi":"https://doi.org/10.1186/s12885-026-17203-8","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s12885-026-17203-8","pdf_url":null,"source":{"id":"https://openalex.org/S192926780","display_name":"BMC Cancer","issn_l":"1471-2407","issn":["1471-2407"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Cancer","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","doaj"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://doi.org/10.1186/s12885-026-17203-8","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5099632875","display_name":"Tingting Ren","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1294606314","display_name":"Beijing Tongren Hospital","ror":"https://ror.org/013e4n276","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I1294606314"]},{"id":"https://openalex.org/I183519381","display_name":"Capital Medical University","ror":"https://ror.org/013xs5b60","country_code":"CN","type":"education","lineage":["https://openalex.org/I183519381"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Tingting Ren","raw_affiliation_strings":["Beijing Institute of Ophthalmology, Beijing Tongren Hospital, Beijing Tongren Eye Center, Capital Medical University, Beijing, 100730, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Beijing Institute of Ophthalmology, Beijing Tongren Hospital, Beijing Tongren Eye Center, Capital Medical University, Beijing, 100730, China","institution_ids":["https://openalex.org/I1294606314","https://openalex.org/I183519381"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5159706385","display_name":"Jing Li","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1294606314","display_name":"Beijing Tongren Hospital","ror":"https://ror.org/013e4n276","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I1294606314"]},{"id":"https://openalex.org/I183519381","display_name":"Capital Medical University","ror":"https://ror.org/013xs5b60","country_code":"CN","type":"education","lineage":["https://openalex.org/I183519381"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Jing Li","raw_affiliation_strings":["Beijing Institute of Ophthalmology, Beijing Tongren Hospital, Beijing Tongren Eye Center, Capital Medical University, Beijing, 100730, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Beijing Institute of Ophthalmology, Beijing Tongren Hospital, Beijing Tongren Eye Center, Capital Medical University, Beijing, 100730, China","institution_ids":["https://openalex.org/I1294606314","https://openalex.org/I183519381"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5159700385","display_name":"Nan Wang","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1294606314","display_name":"Beijing Tongren Hospital","ror":"https://ror.org/013e4n276","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I1294606314"]},{"id":"https://openalex.org/I183519381","display_name":"Capital Medical University","ror":"https://ror.org/013xs5b60","country_code":"CN","type":"education","lineage":["https://openalex.org/I183519381"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Nan Wang","raw_affiliation_strings":["Beijing Institute of Ophthalmology, Beijing Tongren Hospital, Beijing Tongren Eye Center, Capital Medical University, Beijing, 100730, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Beijing Institute of Ophthalmology, Beijing Tongren Hospital, Beijing Tongren Eye Center, Capital Medical University, Beijing, 100730, China","institution_ids":["https://openalex.org/I1294606314","https://openalex.org/I183519381"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5136387941","display_name":"Liangyuan Xu","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1294606314","display_name":"Beijing Tongren Hospital","ror":"https://ror.org/013e4n276","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I1294606314"]},{"id":"https://openalex.org/I183519381","display_name":"Capital Medical University","ror":"https://ror.org/013xs5b60","country_code":"CN","type":"education","lineage":["https://openalex.org/I183519381"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Liangyuan Xu","raw_affiliation_strings":["Beijing Institute of Ophthalmology, Beijing Tongren Hospital, Beijing Tongren Eye Center, Capital Medical University, Beijing, 100730, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Beijing Institute of Ophthalmology, Beijing Tongren Hospital, Beijing Tongren Eye Center, Capital Medical University, Beijing, 100730, China","institution_ids":["https://openalex.org/I1294606314","https://openalex.org/I183519381"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5084213194","display_name":"Qihan Guo","orcid":"https://orcid.org/0000-0002-4158-3623","observed_orcids":["https://orcid.org/0000-0002-4158-3623"]},"institutions":[{"id":"https://openalex.org/I1294606314","display_name":"Beijing Tongren Hospital","ror":"https://ror.org/013e4n276","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I1294606314"]},{"id":"https://openalex.org/I183519381","display_name":"Capital Medical University","ror":"https://ror.org/013xs5b60","country_code":"CN","type":"education","lineage":["https://openalex.org/I183519381"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Qihan Guo","raw_affiliation_strings":["Beijing Institute of Ophthalmology, Beijing Tongren Hospital, Beijing Tongren Eye Center, Capital Medical University, Beijing, 100730, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Beijing Institute of Ophthalmology, Beijing Tongren Hospital, Beijing Tongren Eye Center, Capital Medical University, Beijing, 100730, China","institution_ids":["https://openalex.org/I1294606314","https://openalex.org/I183519381"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5059770552","display_name":"Haihan Yan","orcid":"https://orcid.org/0000-0003-1710-2890","observed_orcids":["https://orcid.org/0000-0003-1710-2890"]},"institutions":[{"id":"https://openalex.org/I1294606314","display_name":"Beijing Tongren Hospital","ror":"https://ror.org/013e4n276","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I1294606314"]},{"id":"https://openalex.org/I183519381","display_name":"Capital Medical University","ror":"https://ror.org/013xs5b60","country_code":"CN","type":"education","lineage":["https://openalex.org/I183519381"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Haihan Yan","raw_affiliation_strings":["Beijing Institute of Ophthalmology, Beijing Tongren Hospital, Beijing Tongren Eye Center, Capital Medical University, Beijing, 100730, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Beijing Institute of Ophthalmology, Beijing Tongren Hospital, Beijing Tongren Eye Center, Capital Medical University, Beijing, 100730, China","institution_ids":["https://openalex.org/I1294606314","https://openalex.org/I183519381"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5126756943","display_name":"Yufei Zhang","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1294606314","display_name":"Beijing Tongren Hospital","ror":"https://ror.org/013e4n276","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I1294606314"]},{"id":"https://openalex.org/I183519381","display_name":"Capital Medical University","ror":"https://ror.org/013xs5b60","country_code":"CN","type":"education","lineage":["https://openalex.org/I183519381"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yufei Zhang","raw_affiliation_strings":["Beijing Institute of Ophthalmology, Beijing Tongren Hospital, Beijing Tongren Eye Center, Capital Medical University, Beijing, 100730, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Beijing Institute of Ophthalmology, Beijing Tongren Hospital, Beijing Tongren Eye Center, Capital Medical University, Beijing, 100730, China","institution_ids":["https://openalex.org/I1294606314","https://openalex.org/I183519381"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5075287990","display_name":"RunZi YANG","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1294606314","display_name":"Beijing Tongren Hospital","ror":"https://ror.org/013e4n276","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I1294606314"]},{"id":"https://openalex.org/I183519381","display_name":"Capital Medical University","ror":"https://ror.org/013xs5b60","country_code":"CN","type":"education","lineage":["https://openalex.org/I183519381"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Runzi Yang","raw_affiliation_strings":["Beijing Institute of Ophthalmology, Beijing Tongren Hospital, Beijing Tongren Eye Center, Capital Medical University, Beijing, 100730, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Beijing Institute of Ophthalmology, Beijing Tongren Hospital, Beijing Tongren Eye Center, Capital Medical University, Beijing, 100730, China","institution_ids":["https://openalex.org/I1294606314","https://openalex.org/I183519381"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5129857091","display_name":"Taiyao Wang","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1294606314","display_name":"Beijing Tongren Hospital","ror":"https://ror.org/013e4n276","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I1294606314"]},{"id":"https://openalex.org/I183519381","display_name":"Capital Medical University","ror":"https://ror.org/013xs5b60","country_code":"CN","type":"education","lineage":["https://openalex.org/I183519381"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Taiyao Wang","raw_affiliation_strings":["Beijing Institute of Ophthalmology, Beijing Tongren Hospital, Beijing Tongren Eye Center, Capital Medical University, Beijing, 100730, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Beijing Institute of Ophthalmology, Beijing Tongren Hospital, Beijing Tongren Eye Center, Capital Medical University, Beijing, 100730, China","institution_ids":["https://openalex.org/I1294606314","https://openalex.org/I183519381"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5159644699","display_name":"Tengyu Gao","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1294606314","display_name":"Beijing Tongren Hospital","ror":"https://ror.org/013e4n276","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I1294606314"]},{"id":"https://openalex.org/I183519381","display_name":"Capital Medical University","ror":"https://ror.org/013xs5b60","country_code":"CN","type":"education","lineage":["https://openalex.org/I183519381"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Tengyu Gao","raw_affiliation_strings":["Beijing Institute of Ophthalmology, Beijing Tongren Hospital, Beijing Tongren Eye Center, Capital Medical University, Beijing, 100730, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Beijing Institute of Ophthalmology, Beijing Tongren Hospital, Beijing Tongren Eye Center, Capital Medical University, Beijing, 100730, China","institution_ids":["https://openalex.org/I1294606314","https://openalex.org/I183519381"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5153406270","display_name":"Liang Wang","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1294606314","display_name":"Beijing Tongren Hospital","ror":"https://ror.org/013e4n276","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I1294606314"]},{"id":"https://openalex.org/I183519381","display_name":"Capital Medical University","ror":"https://ror.org/013xs5b60","country_code":"CN","type":"education","lineage":["https://openalex.org/I183519381"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Liang Wang","raw_affiliation_strings":["Department of Hematology, Beijing Tongren Hospital, Capital Medical University, Beijing, 100730, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Hematology, Beijing Tongren Hospital, Capital Medical University, Beijing, 100730, China","institution_ids":["https://openalex.org/I1294606314","https://openalex.org/I183519381"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5159648891","display_name":"Jianmin Ma","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1294606314","display_name":"Beijing Tongren Hospital","ror":"https://ror.org/013e4n276","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I1294606314"]},{"id":"https://openalex.org/I183519381","display_name":"Capital Medical University","ror":"https://ror.org/013xs5b60","country_code":"CN","type":"education","lineage":["https://openalex.org/I183519381"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Jianmin Ma","raw_affiliation_strings":["Beijing Institute of Ophthalmology, Beijing Tongren Hospital, Beijing Tongren Eye Center, Capital Medical University, Beijing, 100730, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Beijing Institute of Ophthalmology, Beijing Tongren Hospital, Beijing Tongren Eye Center, Capital Medical University, Beijing, 100730, China","institution_ids":["https://openalex.org/I1294606314","https://openalex.org/I183519381"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5159648891"],"corresponding_institution_ids":["https://openalex.org/I1294606314","https://openalex.org/I183519381"],"apc_list":{"value":3390,"currency":"USD","value_usd":3390},"apc_paid":{"value":3390,"currency":"USD","value_usd":3390},"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.83713826,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10185","display_name":"Lymphoma Diagnosis and Treatment","score":0.9897000193595886,"subfield":{"id":"https://openalex.org/subfields/2734","display_name":"Pathology and Forensic Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10185","display_name":"Lymphoma Diagnosis and Treatment","score":0.9897000193595886,"subfield":{"id":"https://openalex.org/subfields/2734","display_name":"Pathology and Forensic Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11328","display_name":"Ocular Oncology and Treatments","score":0.0071000000461936,"subfield":{"id":"https://openalex.org/subfields/2731","display_name":"Ophthalmology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12212","display_name":"CNS Lymphoma Diagnosis and Treatment","score":0.0010000000474974513,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Clinical Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/mantle-cell-lymphoma","display_name":"mantle cell lymphoma","score":0.9990000128746033},{"id":"https://openalex.org/keywords/orbital-involvement","display_name":"orbital involvement","score":0.9240000247955322},{"id":"https://openalex.org/keywords/eyelid-mass","display_name":"eyelid mass","score":0.7799999713897705},{"id":"https://openalex.org/keywords/proptosis","display_name":"proptosis","score":0.8330000042915344},{"id":"https://openalex.org/keywords/ocular-motility-disorders","display_name":"eye movement disorders","score":0.9480000138282776},{"id":"https://openalex.org/keywords/lacrimal-gland-involvement","display_name":"lacrimal gland involvement","score":0.8180000185966492},{"id":"https://openalex.org/keywords/extraocular-muscles","display_name":"extraocular muscles","score":0.8980000019073486},{"id":"https://openalex.org/keywords/cyclin-d1","display_name":"cyclin D1","score":0.8149999976158142},{"id":"https://openalex.org/keywords/cd20","display_name":"CD20","score":0.7049999833106995},{"id":"https://openalex.org/keywords/bcl-2","display_name":"Bcl-2","score":0.9520000219345093},{"id":"https://openalex.org/keywords/systemic-chemotherapy","display_name":"systemic chemotherapy","score":0.7360000014305115},{"id":"https://openalex.org/keywords/radiotherapy","display_name":"radiotherapy","score":0.7179999947547913},{"id":"https://openalex.org/keywords/progression-free-survival","display_name":"progression-free survival","score":0.949999988079071},{"id":"https://openalex.org/keywords/relapse","display_name":"relapse","score":0.699999988079071}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8932999968528748},{"id":"https://openalex.org/C167135981","wikidata":"https://www.wikidata.org/wiki/Q2146302","display_name":"Retrospective cohort study","level":2,"score":0.6930999755859375},{"id":"https://openalex.org/C2777525834","wikidata":"https://www.wikidata.org/wiki/Q268713","display_name":"Mantle cell lymphoma","level":3,"score":0.571399986743927},{"id":"https://openalex.org/C2779298748","wikidata":"https://www.wikidata.org/wiki/Q913628","display_name":"Lacrimal gland","level":2,"score":0.5692999958992004},{"id":"https://openalex.org/C2781302119","wikidata":"https://www.wikidata.org/wiki/Q48228","display_name":"Eyelid","level":2,"score":0.49410000443458557},{"id":"https://openalex.org/C196644772","wikidata":"https://www.wikidata.org/wiki/Q3884964","display_name":"Orbit (dynamics)","level":2,"score":0.47029998898506165},{"id":"https://openalex.org/C2775934546","wikidata":"https://www.wikidata.org/wiki/Q179991","display_name":"Biopsy","level":2,"score":0.4187000095844269},{"id":"https://openalex.org/C2780140570","wikidata":"https://www.wikidata.org/wiki/Q3545481","display_name":"Surgical oncology","level":2,"score":0.39410001039505005},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.3612000048160553},{"id":"https://openalex.org/C2777601897","wikidata":"https://www.wikidata.org/wiki/Q3409113","display_name":"Presentation (obstetrics)","level":2,"score":0.35760000348091125},{"id":"https://openalex.org/C2780849966","wikidata":"https://www.wikidata.org/wiki/Q170758","display_name":"Lymph node","level":2,"score":0.3375000059604645},{"id":"https://openalex.org/C205545832","wikidata":"https://www.wikidata.org/wiki/Q17156455","display_name":"Young adult","level":2,"score":0.3127000033855438},{"id":"https://openalex.org/C126838900","wikidata":"https://www.wikidata.org/wiki/Q77604","display_name":"Radiology","level":1,"score":0.30079999566078186},{"id":"https://openalex.org/C2780581723","wikidata":"https://www.wikidata.org/wiki/Q775940","display_name":"Diplopia","level":2,"score":0.2987000048160553},{"id":"https://openalex.org/C2909668393","wikidata":"https://www.wikidata.org/wiki/Q156075","display_name":"Orbital Diseases","level":4,"score":0.2971000075340271},{"id":"https://openalex.org/C2909463153","wikidata":"https://www.wikidata.org/wiki/Q496812","display_name":"Leukocytopenia","level":3,"score":0.29100000858306885},{"id":"https://openalex.org/C526584372","wikidata":"https://www.wikidata.org/wiki/Q16399","display_name":"Thyroid","level":2,"score":0.287200003862381},{"id":"https://openalex.org/C143409427","wikidata":"https://www.wikidata.org/wiki/Q161238","display_name":"Magnetic resonance imaging","level":2,"score":0.28360000252723694},{"id":"https://openalex.org/C2779338263","wikidata":"https://www.wikidata.org/wiki/Q208414","display_name":"Lymphoma","level":2,"score":0.2833000123500824},{"id":"https://openalex.org/C101265243","wikidata":"https://www.wikidata.org/wiki/Q384445","display_name":"Case series","level":3,"score":0.2773999869823456},{"id":"https://openalex.org/C2776807875","wikidata":"https://www.wikidata.org/wiki/Q533979","display_name":"Extraocular muscles","level":2,"score":0.2759000062942505},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.26969999074935913},{"id":"https://openalex.org/C187212893","wikidata":"https://www.wikidata.org/wiki/Q123028","display_name":"Pediatrics","level":1,"score":0.2639999985694885},{"id":"https://openalex.org/C16005928","wikidata":"https://www.wikidata.org/wiki/Q171171","display_name":"Dermatology","level":1,"score":0.26080000400543213},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.2605000138282776}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1186/s12885-026-17203-8","doi":"https://doi.org/10.1186/s12885-026-17203-8","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s12885-026-17203-8","pdf_url":null,"source":{"id":"https://openalex.org/S192926780","display_name":"BMC Cancer","issn_l":"1471-2407","issn":["1471-2407"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Cancer","raw_type":"journal-article"}],"best_oa_location":{"id":"doi:10.1186/s12885-026-17203-8","doi":"https://doi.org/10.1186/s12885-026-17203-8","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s12885-026-17203-8","pdf_url":null,"source":{"id":"https://openalex.org/S192926780","display_name":"BMC Cancer","issn_l":"1471-2407","issn":["1471-2407"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Cancer","raw_type":"journal-article"},"sustainable_development_goals":[{"score":1.0,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2055432403","https://openalex.org/W2094896740","https://openalex.org/W2035135228","https://openalex.org/W2089292691","https://openalex.org/W1975304979","https://openalex.org/W2046798131","https://openalex.org/W3020863315","https://openalex.org/W2050940592","https://openalex.org/W2783841710","https://openalex.org/W2767921494"],"abstract_inverted_index":{"To":[0],"summarize":[1],"the":[2,74,114,183],"clinical":[3,226],"features,":[4],"treatment,":[5],"and":[6,36,40,45,49,65,101,122,136,152,163,192,200,207,221,235,246],"outcomes":[7],"of":[8,228],"mantle":[9],"cell":[10],"lymphoma":[11],"(MCL)":[12],"with":[13,23,129,157,180,230,249],"orbital":[14,24,84,109,231],"involvement.":[15,85],"This":[16],"descriptive":[17],"retrospective":[18],"study":[19],"included":[20],"13":[21],"patients":[22,61,106,128,166,179,190,237,248],"involvement":[25,140,232],"by":[26],"MCL":[27,229],"treated":[28],"at":[29,240],"Beijing":[30],"Tongren":[31],"Hospital":[32],"between":[33],"January":[34],"2010":[35],"May":[37],"2025.":[38],"Clinical":[39],"follow-up":[41,181,185],"data":[42],"were":[43,52,63,89,141,146,204],"analyzed,":[44],"published":[46],"individual":[47],"cases":[48],"case":[50],"series":[51],"reviewed.":[53],"The":[54,86,196,210,225],"median":[55,184],"age":[56],"was":[57,73,186],"65":[58],"years.":[59],"10":[60],"(76.9%)":[62],"male,":[64],"9":[66,78],"(69.2%)":[67],"had":[68,82,107],"bilateral":[69,217],"disease.":[70],"Orbital":[71],"disease":[72],"initial":[75],"presentation":[76,227],"in":[77,154],"patients,":[79,156],"whereas":[80],"4":[81],"secondary":[83],"main":[87],"manifestations":[88],"eyelid":[90,115],"swelling":[91],"or":[92],"mass":[93],"(12/13;":[94,116],"92.3%),":[95,117],"ocular":[96],"motility":[97],"disorders":[98],"(8/13;":[99],"61.5%),":[100],"proptosis":[102],"(6/13;":[103],"46.2%).":[104],"All":[105],"multi-structure":[108],"involvement,":[110],"most":[111,142,236],"often":[112],"affecting":[113],"lacrimal":[118],"gland":[119],"(11/13;":[120,125],"84.6%),":[121],"extraocular":[123],"muscles":[124],"84.6%).":[126],"Among":[127,177],"systemic":[130,168],"evaluation,":[131],"lymph":[132],"node":[133],"(10/10;":[134],"100%)":[135],"nasopharyngeal":[137],"(9/10;":[138],"90.0%)":[139],"common.":[143],"Tumor":[144],"cells":[145],"positive":[147],"for":[148,160,258],"cyclin":[149],"D1,":[150],"CD20,":[151],"Bcl-2":[153],"all":[155],"typical":[158],"negativity":[159],"CD23,":[161],"Bcl-6,":[162],"CD10.":[164],"Ten":[165],"received":[167,174],"chemotherapy,":[169],"including":[170],"2":[171],"who":[172],"also":[173],"local":[175],"radiotherapy.":[176],"11":[178],"data,":[182],"48":[187],"months;":[188],"three":[189],"relapsed,":[191],"no":[193],"deaths":[194],"occurred.":[195],"estimated":[197],"1-,":[198],"3-,":[199],"5-year":[201],"PFS":[202],"rates":[203],"90%,":[205],"80%,":[206],"67%,":[208],"respectively.":[209],"literature":[211],"review":[212],"confirmed":[213],"male":[214],"predominance,":[215],"frequent":[216],"disease,":[218],"advanced-stage":[219],"presentation,":[220],"heterogeneous":[222],"treatment":[223],"patterns.":[224],"lacks":[233],"specificity,":[234],"are":[238],"diagnosed":[239],"an":[241],"advanced":[242],"stage.":[243],"For":[244],"middle-aged":[245],"elderly":[247],"only":[250],"transient":[251],"steroid":[252],"responsiveness,":[253],"early":[254],"biopsy":[255],"is":[256],"crucial":[257],"accurate":[259],"diagnosis.":[260]},"counts_by_year":[],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2026-10-27T00:00:00"}