{"id":"https://openalex.org/W7223569072","doi":"https://doi.org/10.1038/s41467-026-78820-2","title":"Ureterovesical junction: a stem cell niche for ureteral urothelial renewal and bladder urothelial injury repair","display_name":"Ureterovesical junction: a stem cell niche for ureteral urothelial renewal and bladder urothelial injury repair","publication_year":2026,"publication_date":"2026-10-26","ids":{"openalex":"https://openalex.org/W7223569072","doi":"https://doi.org/10.1038/s41467-026-78820-2"},"language":"en","primary_location":{"id":"doi:10.1038/s41467-026-78820-2","doi":"https://doi.org/10.1038/s41467-026-78820-2","is_oa":true,"landing_page_url":"https://doi.org/10.1038/s41467-026-78820-2","pdf_url":"https://www.nature.com/articles/s41467-026-78820-2_reference.pdf","source":{"id":"https://openalex.org/S64187185","display_name":"Nature Communications","issn_l":"2041-1723","issn":["2041-1723"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","doaj","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","oarl","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319908","host_organization_name":"Nature Portfolio","host_organization_lineage":["https://openalex.org/P4310319908","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Nature Portfolio","Springer Nature"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nature Communications","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","doaj"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://www.nature.com/articles/s41467-026-78820-2_reference.pdf","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5120644969","display_name":"Yi Liao","orcid":"https://orcid.org/0000-0002-7724-1799","observed_orcids":["https://orcid.org/0000-0002-7724-1799"]},"institutions":[{"id":"https://openalex.org/I2800015068","display_name":"VA NY Harbor Healthcare System","ror":"https://ror.org/03s5r4e84","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1322918889","https://openalex.org/I2799886695","https://openalex.org/I2800015068","https://openalex.org/I4210094901"]},{"id":"https://openalex.org/I57206974","display_name":"New York University","ror":"https://ror.org/0190ak572","country_code":"US","type":"education","lineage":["https://openalex.org/I57206974"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Yi Liao","raw_affiliation_strings":["Department of Urology, New York University Grossman School of Medicine, New York, 10016, NY, USA","Veterans Affairs New York Harbor Healthcare System, Manhattan Campus, New York, 10010, NY, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Urology, New York University Grossman School of Medicine, New York, 10016, NY, USA","institution_ids":["https://openalex.org/I57206974"]},{"raw_affiliation_string":"Veterans Affairs New York Harbor Healthcare System, Manhattan Campus, New York, 10010, NY, USA","institution_ids":["https://openalex.org/I2800015068"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5159565605","display_name":"Fenglin Zhang","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I57206974","display_name":"New York University","ror":"https://ror.org/0190ak572","country_code":"US","type":"education","lineage":["https://openalex.org/I57206974"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Fenglin Zhang","raw_affiliation_strings":["Department of Urology, New York University Grossman School of Medicine, New York, 10016, NY, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Urology, New York University Grossman School of Medicine, New York, 10016, NY, USA","institution_ids":["https://openalex.org/I57206974"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5159493163","display_name":"Yan Liu","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2800015068","display_name":"VA NY Harbor Healthcare System","ror":"https://ror.org/03s5r4e84","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1322918889","https://openalex.org/I2799886695","https://openalex.org/I2800015068","https://openalex.org/I4210094901"]},{"id":"https://openalex.org/I57206974","display_name":"New York University","ror":"https://ror.org/0190ak572","country_code":"US","type":"education","lineage":["https://openalex.org/I57206974"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Yan Liu","raw_affiliation_strings":["Department of Urology, New York University Grossman School of Medicine, New York, 10016, NY, USA","Veterans Affairs New York Harbor Healthcare System, Manhattan Campus, New York, 10010, NY, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Urology, New York University Grossman School of Medicine, New York, 10016, NY, USA","institution_ids":["https://openalex.org/I57206974"]},{"raw_affiliation_string":"Veterans Affairs New York Harbor Healthcare System, Manhattan Campus, New York, 10010, NY, USA","institution_ids":["https://openalex.org/I2800015068"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5159494786","display_name":"Xiaohong Li","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I57206974","display_name":"New York University","ror":"https://ror.org/0190ak572","country_code":"US","type":"education","lineage":["https://openalex.org/I57206974"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Xiaohong Li","raw_affiliation_strings":["Department of Cell Biology, New York University School of Medicine, New York, 10016, NY, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cell Biology, New York University School of Medicine, New York, 10016, NY, USA","institution_ids":["https://openalex.org/I57206974"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5015925521","display_name":"Fiona I. Kuo","orcid":"https://orcid.org/0000-0003-1329-7272","observed_orcids":["https://orcid.org/0000-0003-1329-7272"]},"institutions":[{"id":"https://openalex.org/I57206974","display_name":"New York University","ror":"https://ror.org/0190ak572","country_code":"US","type":"education","lineage":["https://openalex.org/I57206974"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Fiona I. Kuo","raw_affiliation_strings":["Department of Cell Biology, New York University School of Medicine, New York, 10016, NY, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cell Biology, New York University School of Medicine, New York, 10016, NY, USA","institution_ids":["https://openalex.org/I57206974"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5159544569","display_name":"Ten Hou","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I57206974","display_name":"New York University","ror":"https://ror.org/0190ak572","country_code":"US","type":"education","lineage":["https://openalex.org/I57206974"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Ten Hou","raw_affiliation_strings":["Department of Cell Biology, New York University School of Medicine, New York, 10016, NY, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cell Biology, New York University School of Medicine, New York, 10016, NY, USA","institution_ids":["https://openalex.org/I57206974"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100663515","display_name":"Yuan Wei","orcid":"https://orcid.org/0000-0001-8058-8542","observed_orcids":["https://orcid.org/0000-0001-8058-8542"]},"institutions":[{"id":"https://openalex.org/I57206974","display_name":"New York University","ror":"https://ror.org/0190ak572","country_code":"US","type":"education","lineage":["https://openalex.org/I57206974"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Yuan Wei","raw_affiliation_strings":["Department of Cell Biology, New York University School of Medicine, New York, 10016, NY, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cell Biology, New York University School of Medicine, New York, 10016, NY, USA","institution_ids":["https://openalex.org/I57206974"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5159478333","display_name":"Tak-Wah Wong","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I57206974","display_name":"New York University","ror":"https://ror.org/0190ak572","country_code":"US","type":"education","lineage":["https://openalex.org/I57206974"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Tak-Wah Wong","raw_affiliation_strings":["Department of Cell Biology, New York University School of Medicine, New York, 10016, NY, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cell Biology, New York University School of Medicine, New York, 10016, NY, USA","institution_ids":["https://openalex.org/I57206974"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5011556876","display_name":"Herbert Lepor","orcid":"https://orcid.org/0000-0002-7839-835X","observed_orcids":["https://orcid.org/0000-0002-7839-835X"]},"institutions":[{"id":"https://openalex.org/I57206974","display_name":"New York University","ror":"https://ror.org/0190ak572","country_code":"US","type":"education","lineage":["https://openalex.org/I57206974"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Herbert Lepor","raw_affiliation_strings":["Department of Urology, New York University Grossman School of Medicine, New York, 10016, NY, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Urology, New York University Grossman School of Medicine, New York, 10016, NY, USA","institution_ids":["https://openalex.org/I57206974"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113583296","display_name":"Ellen Shapiro","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I57206974","display_name":"New York University","ror":"https://ror.org/0190ak572","country_code":"US","type":"education","lineage":["https://openalex.org/I57206974"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Ellen Shapiro","raw_affiliation_strings":["Department of Urology, New York University Grossman School of Medicine, New York, 10016, NY, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Urology, New York University Grossman School of Medicine, New York, 10016, NY, USA","institution_ids":["https://openalex.org/I57206974"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5072062044","display_name":"Fang\u2010Ming Deng","orcid":"https://orcid.org/0000-0002-1156-0930","observed_orcids":["https://orcid.org/0000-0002-1156-0930"]},"institutions":[{"id":"https://openalex.org/I57206974","display_name":"New York University","ror":"https://ror.org/0190ak572","country_code":"US","type":"education","lineage":["https://openalex.org/I57206974"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Fang-Ming Deng","raw_affiliation_strings":["Department of Pathology, New York University School of Medicine, New York, 10016, NY, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pathology, New York University School of Medicine, New York, 10016, NY, USA","institution_ids":["https://openalex.org/I57206974"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5085800142","display_name":"Cathy Lee Mendelsohn","orcid":"https://orcid.org/0000-0002-4026-4073","observed_orcids":["https://orcid.org/0000-0002-4026-4073"]},"institutions":[{"id":"https://openalex.org/I2799503643","display_name":"Columbia University Irving Medical Center","ror":"https://ror.org/01esghr10","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2799503643"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Cathy Lee Mendelsohn","raw_affiliation_strings":["Department of Urology, Columbia University Irving Medical Center, New York, 10027, USA"],"raw_orcid":"https://orcid.org/0000-0002-4026-4073","affiliations":[{"raw_affiliation_string":"Department of Urology, Columbia University Irving Medical Center, New York, 10027, USA","institution_ids":["https://openalex.org/I2799503643"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5059105242","display_name":"Xue\u2010Ru Wu","orcid":"https://orcid.org/0000-0001-6058-6291","observed_orcids":["https://orcid.org/0000-0001-6058-6291"]},"institutions":[{"id":"https://openalex.org/I2800015068","display_name":"VA NY Harbor Healthcare System","ror":"https://ror.org/03s5r4e84","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1322918889","https://openalex.org/I2799886695","https://openalex.org/I2800015068","https://openalex.org/I4210094901"]},{"id":"https://openalex.org/I57206974","display_name":"New York University","ror":"https://ror.org/0190ak572","country_code":"US","type":"education","lineage":["https://openalex.org/I57206974"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Xue-Ru Wu","raw_affiliation_strings":["Department of Pathology, New York University School of Medicine, New York, 10016, NY, USA","Department of Urology, New York University Grossman School of Medicine, New York, 10016, NY, USA","Veterans Affairs New York Harbor Healthcare System, Manhattan Campus, New York, 10010, NY, USA"],"raw_orcid":"https://orcid.org/0000-0001-6058-6291","affiliations":[{"raw_affiliation_string":"Department of Pathology, New York University School of Medicine, New York, 10016, NY, USA","institution_ids":["https://openalex.org/I57206974"]},{"raw_affiliation_string":"Department of Urology, New York University Grossman School of Medicine, New York, 10016, NY, USA","institution_ids":["https://openalex.org/I57206974"]},{"raw_affiliation_string":"Veterans Affairs New York Harbor Healthcare System, Manhattan Campus, New York, 10010, NY, USA","institution_ids":["https://openalex.org/I2800015068"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5059105242"],"corresponding_institution_ids":["https://openalex.org/I2800015068","https://openalex.org/I57206974"],"apc_list":{"value":6990,"currency":"USD","value_usd":6990},"apc_paid":{"value":6990,"currency":"USD","value_usd":6990},"fwci":0.0,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":{"value":0.88057923,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10279","display_name":"Urinary Bladder and Prostate Research","score":0.1770000010728836,"subfield":{"id":"https://openalex.org/subfields/2748","display_name":"Urology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10279","display_name":"Urinary Bladder and Prostate Research","score":0.1770000010728836,"subfield":{"id":"https://openalex.org/subfields/2748","display_name":"Urology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12634","display_name":"Ureteral procedures and complications","score":0.14489999413490295,"subfield":{"id":"https://openalex.org/subfields/2729","display_name":"Obstetrics and Gynecology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10458","display_name":"Bladder and Urothelial Cancer Treatments","score":0.14270000159740448,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/ureterovesical-junction","display_name":"ureterovesical junction","score":1.0},{"id":"https://openalex.org/keywords/stem-cell-niche","display_name":"stem cell niche","score":0.7889999747276306},{"id":"https://openalex.org/keywords/bladder-urothelium","display_name":"bladder urothelium","score":0.8629999756813049},{"id":"https://openalex.org/keywords/tissue-regeneration","display_name":"tissue regeneration","score":0.5640000104904175}],"concepts":[{"id":"https://openalex.org/C28328180","wikidata":"https://www.wikidata.org/wiki/Q48196","display_name":"Stem cell","level":2,"score":0.6464999914169312},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.5616000294685364},{"id":"https://openalex.org/C153991713","wikidata":"https://www.wikidata.org/wiki/Q17142856","display_name":"Niche","level":2,"score":0.5375000238418579},{"id":"https://openalex.org/C164794517","wikidata":"https://www.wikidata.org/wiki/Q16729831","display_name":"Stem cell niche","level":4,"score":0.5260000228881836},{"id":"https://openalex.org/C2779762690","wikidata":"https://www.wikidata.org/wiki/Q9382","display_name":"Urinary bladder","level":2,"score":0.4169999957084656},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.39719998836517334},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.384799987077713},{"id":"https://openalex.org/C2777540882","wikidata":"https://www.wikidata.org/wiki/Q11878994","display_name":"Urothelium","level":3,"score":0.34119999408721924},{"id":"https://openalex.org/C2776664737","wikidata":"https://www.wikidata.org/wiki/Q9385","display_name":"Ureter","level":2,"score":0.33480000495910645},{"id":"https://openalex.org/C2778475373","wikidata":"https://www.wikidata.org/wiki/Q6066379","display_name":"Urinary bladder disease","level":3,"score":0.31439998745918274},{"id":"https://openalex.org/C126894567","wikidata":"https://www.wikidata.org/wiki/Q105650","display_name":"Urology","level":1,"score":0.31279999017715454},{"id":"https://openalex.org/C2910041100","wikidata":"https://www.wikidata.org/wiki/Q11878994","display_name":"Urothelial Cell","level":4,"score":0.31060001254081726},{"id":"https://openalex.org/C1491633281","wikidata":"https://www.wikidata.org/wiki/Q7868","display_name":"Cell","level":2,"score":0.2957000136375427},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.2870999872684479},{"id":"https://openalex.org/C198826908","wikidata":"https://www.wikidata.org/wiki/Q1922379","display_name":"Mesenchymal stem cell","level":2,"score":0.2808000147342682},{"id":"https://openalex.org/C3020745361","wikidata":"https://www.wikidata.org/wiki/Q2501186","display_name":"Urothelial cancer","level":4,"score":0.2768000066280365},{"id":"https://openalex.org/C138798377","wikidata":"https://www.wikidata.org/wiki/Q7312502","display_name":"Renal stem cell","level":4,"score":0.27649998664855957},{"id":"https://openalex.org/C3019882237","wikidata":"https://www.wikidata.org/wiki/Q2501186","display_name":"Urothelial carcinoma","level":4,"score":0.27320000529289246},{"id":"https://openalex.org/C2780091579","wikidata":"https://www.wikidata.org/wiki/Q9377","display_name":"Kidney","level":2,"score":0.2554999887943268}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1038/s41467-026-78820-2","doi":"https://doi.org/10.1038/s41467-026-78820-2","is_oa":true,"landing_page_url":"https://doi.org/10.1038/s41467-026-78820-2","pdf_url":"https://www.nature.com/articles/s41467-026-78820-2_reference.pdf","source":{"id":"https://openalex.org/S64187185","display_name":"Nature Communications","issn_l":"2041-1723","issn":["2041-1723"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","doaj","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","oarl","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319908","host_organization_name":"Nature Portfolio","host_organization_lineage":["https://openalex.org/P4310319908","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Nature Portfolio","Springer Nature"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nature Communications","raw_type":"journal-article"}],"best_oa_location":{"id":"doi:10.1038/s41467-026-78820-2","doi":"https://doi.org/10.1038/s41467-026-78820-2","is_oa":true,"landing_page_url":"https://doi.org/10.1038/s41467-026-78820-2","pdf_url":"https://www.nature.com/articles/s41467-026-78820-2_reference.pdf","source":{"id":"https://openalex.org/S64187185","display_name":"Nature Communications","issn_l":"2041-1723","issn":["2041-1723"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","doaj","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","oarl","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319908","host_organization_name":"Nature Portfolio","host_organization_lineage":["https://openalex.org/P4310319908","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Nature Portfolio","Springer Nature"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nature Communications","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.9391000270843506,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G1158796701","display_name":null,"funder_award_id":"1I01BX002049","funder_id":"https://openalex.org/F4320306127","funder_display_name":"U.S. Department of Veterans Affairs"}],"funders":[{"id":"https://openalex.org/F4320306127","display_name":"U.S. Department of Veterans Affairs","ror":"https://ror.org/05rsv9s98"},{"id":"https://openalex.org/F4320309037","display_name":"Office of Research and Development","ror":"https://ror.org/05rsv9s98"},{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W7223569072.pdf","grobid_xml":"https://content.openalex.org/works/W7223569072.grobid-xml"},"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W3030169054","https://openalex.org/W2602516669","https://openalex.org/W2626638406","https://openalex.org/W4211020098","https://openalex.org/W7128851738","https://openalex.org/W4404144018","https://openalex.org/W2078556297","https://openalex.org/W2903070098","https://openalex.org/W2027039143","https://openalex.org/W7203918872"],"abstract_inverted_index":{"Epithelial":[0],"stem":[1,156],"cells":[2,29,40,66,112,137,157,163],"are":[3],"essential":[4],"for":[5],"lineage":[6],"specification,":[7],"tissue":[8],"renewal,":[9],"and":[10,59,83,96,101,107,119,129,143,167,169,174],"regeneration.":[11],"Here":[12],"we":[13],"show":[14],"that":[15,30],"ureterovesical":[16],"junction":[17],"(UVJ)":[18],"of":[19,26,62,99,135,154],"urinary":[20],"tract":[21],"harbors":[22],"a":[23,151],"major":[24,152],"cluster":[25,153],"label-retaining":[27],"urothelial":[28,39,105,111,121,141,155,178],"exhibit":[31],"organoid-forming":[32],"activities.":[33],"During":[34],"lineage-tracing,":[35],"these":[36,89],"Foxa2-expressing":[37],"UVJ":[38,65,115,118,136],"renew":[41,171],"ureteral":[42,172],"urothelium,":[43,64],"but":[44],"do":[45],"not":[46],"migrate":[47,67],"into":[48,69],"the":[49,70,94,133,159],"bladder":[50,55,63,71,74,85,110,120,140,146,177],"during":[51,80],"homeostasis":[52],"or":[53],"mild":[54],"injury.":[56],"Upon":[57],"mechanical":[58],"chemical":[60],"denudation":[61],"rapidly":[68],"to":[72,88],"replace":[73],"urothelium.":[75],"This":[76],"reepithelization":[77],"also":[78],"occurs":[79],"combination":[81],"chemotherapies":[82],"severe":[84,176],"infection.":[86],"Common":[87],"injury":[90],"repair":[91,175],"processes":[92],"is":[93],"early-phase":[95],"selective":[97],"phosphorylation":[98],"TRKA":[100],"AKT":[102],"which":[103],"drives":[104],"proliferation":[106],"differentiation.":[108],"Nascent":[109],"derived":[113],"from":[114],"express":[116],"both":[117],"markers,":[122],"signifying":[123],"active":[124],"remodeling":[125],"influenced":[126],"by":[127],"intrinsic":[128],"extrinsic":[130],"factors.":[131],"Modulating":[132],"activities":[134],"may":[138],"enhance":[139],"regeneration":[142],"combat":[144],"challenging":[145],"diseases.":[147],"The":[148],"authors":[149],"identified":[150],"at":[158],"ureter-bladder":[160],"junction.":[161],"These":[162],"efficiently":[164],"formed":[165],"colonies":[166],"organoids,":[168],"they":[170],"urothelium":[173],"injuries.":[179]},"counts_by_year":[],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2026-10-26T00:00:00"}