{"id":"https://openalex.org/W7223564196","doi":"https://doi.org/10.1016/j.htct.2026.107982","title":"ASSOCIA\u00c7\u00c3O ENTRE O GEN\u00d3TIPO DE F9, O STATUS DE CRM E O FEN\u00d3TIPO HEMORR\u00c1GICO NA HEMOFILIA B GRAVE DURANTE O TRATAMENTO DE REPOSI\u00c7\u00c3O DE FATOR IX SOB DEMANDA","display_name":"ASSOCIA\u00c7\u00c3O ENTRE O GEN\u00d3TIPO DE F9, O STATUS DE CRM E O FEN\u00d3TIPO HEMORR\u00c1GICO NA HEMOFILIA B GRAVE DURANTE O TRATAMENTO DE REPOSI\u00c7\u00c3O DE FATOR IX SOB DEMANDA","publication_year":2026,"publication_date":"2026-10-01","ids":{"openalex":"https://openalex.org/W7223564196","doi":"https://doi.org/10.1016/j.htct.2026.107982"},"language":"en","primary_location":{"id":"pmh:oai:doaj.org/article:7bc6f30ee0f14a40a8b61c30f93f5139","doi":"https://doi.org/10.1016/j.htct.2026.107982","is_oa":false,"landing_page_url":"https://doaj.org/article/7bc6f30ee0f14a40a8b61c30f93f5139","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Hematology, Transfusion and Cell Therapy, Vol 48, Iss , Pp 107982- (2026)","raw_type":"article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["doaj"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5157507905","display_name":"Thais H. Trento","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Thais H TRENTO","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5077769631","display_name":"J\u00e9ssica O. Frade-Guanaes","orcid":"https://orcid.org/0000-0003-1008-4458","observed_orcids":["https://orcid.org/0000-0003-1008-4458"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Jessica O FRADE-GUANAES","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5054724297","display_name":"L\u00facia H. Siqueira","orcid":"https://orcid.org/0009-0002-4928-123X","observed_orcids":["https://orcid.org/0009-0002-4928-123X"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Lucia H SIQUEIRA","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5159181314","display_name":"Silmara A L MONTALV\u00c3O","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Silmara A L MONTALV\u00c3O","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5159503111","display_name":"Alessandra N L PREZOTTI","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Alessandra N L PREZOTTI","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5159504306","display_name":"Debora M C R SANTIAGO","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Debora M C R SANTIAGO","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5157548998","display_name":"Julia C.L. Cazarini","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Julia C L CAZARINI","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5013407757","display_name":"Gabriela G Yamaguti-Hayakawa","orcid":"https://orcid.org/0000-0002-0350-8171","observed_orcids":["https://orcid.org/0000-0002-0350-8171"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Gabriela G YAMAGUTI-HAYAKAWA","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5033744481","display_name":"Margareth C. Ozelo","orcid":"https://orcid.org/0000-0001-5938-0675","observed_orcids":["https://orcid.org/0000-0001-5938-0675"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Margareth C OZELO","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.82918082,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11280","display_name":"Hemophilia Treatment and Research","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11280","display_name":"Hemophilia Treatment and Research","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10746","display_name":"Platelet Disorders and Treatments","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11917","display_name":"Coagulation, Bradykinin, Polyphosphates, and Angioedema","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/hemophilia-b","display_name":"hemophilia B","score":0.8220000267028809},{"id":"https://openalex.org/keywords/factor-ix-replacement-therapy","display_name":"factor IX replacement therapy","score":0.5699999928474426},{"id":"https://openalex.org/keywords/on-demand-treatment","display_name":"on-demand treatment","score":0.7760000228881836},{"id":"https://openalex.org/keywords/annualized-bleeding-rate","display_name":"annualized bleeding rate","score":0.7789999842643738},{"id":"https://openalex.org/keywords/factor-ix-inhibitors","display_name":"factor IX inhibitors","score":0.6129999756813049},{"id":"https://openalex.org/keywords/splice-variants","display_name":"splice variants","score":0.7440000176429749},{"id":"https://openalex.org/keywords/frameshift-mutation","display_name":"frameshift mutation","score":0.8640000224113464},{"id":"https://openalex.org/keywords/missense-mutations","display_name":"missense mutations","score":0.9269999861717224},{"id":"https://openalex.org/keywords/inhibitor-development","display_name":"inhibitor development","score":0.3540000021457672}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.5911999940872192},{"id":"https://openalex.org/C29456083","wikidata":"https://www.wikidata.org/wiki/Q1221899","display_name":"Gynecology","level":1,"score":0.35510000586509705},{"id":"https://openalex.org/C153911025","wikidata":"https://www.wikidata.org/wiki/Q7202","display_name":"Molecular biology","level":1,"score":0.3172000050544739},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.2777999937534332},{"id":"https://openalex.org/C15708023","wikidata":"https://www.wikidata.org/wiki/Q80083","display_name":"Humanities","level":1,"score":0.2597000002861023},{"id":"https://openalex.org/C90924648","wikidata":"https://www.wikidata.org/wiki/Q120569","display_name":"Gastroenterology","level":1,"score":0.24449999630451202},{"id":"https://openalex.org/C72563966","wikidata":"https://www.wikidata.org/wiki/Q1303415","display_name":"Cohort","level":2,"score":0.2320999950170517},{"id":"https://openalex.org/C187212893","wikidata":"https://www.wikidata.org/wiki/Q123028","display_name":"Pediatrics","level":1,"score":0.22630000114440918},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.22529999911785126},{"id":"https://openalex.org/C2777910003","wikidata":"https://www.wikidata.org/wiki/Q1707292","display_name":"Asymptomatic","level":2,"score":0.2159000039100647}],"mesh":[],"locations_count":1,"locations":[{"id":"pmh:oai:doaj.org/article:7bc6f30ee0f14a40a8b61c30f93f5139","doi":"https://doi.org/10.1016/j.htct.2026.107982","is_oa":false,"landing_page_url":"https://doaj.org/article/7bc6f30ee0f14a40a8b61c30f93f5139","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Hematology, Transfusion and Cell Therapy, Vol 48, Iss , Pp 107982- (2026)","raw_type":"article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.9940000176429749,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W6999075932","https://openalex.org/W7064602284","https://openalex.org/W2741708036","https://openalex.org/W6999095418","https://openalex.org/W3153328207","https://openalex.org/W7169764707","https://openalex.org/W4285811293","https://openalex.org/W2113057220","https://openalex.org/W4389248714","https://openalex.org/W7006560640"],"abstract_inverted_index":null,"counts_by_year":[],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2026-10-26T00:00:00"}