{"id":"https://openalex.org/W7223464693","doi":"https://doi.org/10.1002/fsn3.72421","title":"Using Olive Leaves to Enrich Olive Oil With Oleuropein Aglycone","display_name":"Using Olive Leaves to Enrich Olive Oil With Oleuropein Aglycone","publication_year":2026,"publication_date":"2026-10-01","ids":{"openalex":"https://openalex.org/W7223464693","doi":"https://doi.org/10.1002/fsn3.72421","pmid":"https://pubmed.ncbi.nlm.nih.gov/42927163","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/13694744"},"language":"en","primary_location":{"id":"doi:10.1002/fsn3.72421","doi":"https://doi.org/10.1002/fsn3.72421","is_oa":true,"landing_page_url":"https://doi.org/10.1002/fsn3.72421","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/fsn3.72421","source":{"id":"https://openalex.org/S2764587058","display_name":"Food Science & Nutrition","issn_l":"2048-7177","issn":["2048-7177"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","jufo-1","ki-jl-1","norway-1","poland-100","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Food Science & Nutrition","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/fsn3.72421","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5159388138","display_name":"Jade te Bogt","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I52179390","display_name":"University of Waikato","ror":"https://ror.org/013fsnh78","country_code":"NZ","type":"education","lineage":["https://openalex.org/I52179390"]}],"countries":["NZ"],"is_corresponding":false,"raw_author_name":"Jade te Bogt","raw_affiliation_strings":["School of Science, Division of STEM The University of Waikato  Hamilton New Zealand"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Science, Division of STEM The University of Waikato  Hamilton New Zealand","institution_ids":["https://openalex.org/I52179390"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5038168066","display_name":"D.J. Speed","orcid":"https://orcid.org/0009-0009-5977-1284","observed_orcids":["https://orcid.org/0009-0009-5977-1284"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"David Speed","raw_affiliation_strings":["ALS Food & Environmental NZ Formerly Analytica Laboratories  Hamilton New Zealand"],"raw_orcid":"https://orcid.org/0009-0009-5977-1284","affiliations":[{"raw_affiliation_string":"ALS Food & Environmental NZ Formerly Analytica Laboratories  Hamilton New Zealand","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5035927919","display_name":"Ralf C. Schlothauer","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Ralf C. Schlothauer","raw_affiliation_strings":["Whio Innovations Ltd  Tauranga New Zealand"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Whio Innovations Ltd  Tauranga New Zealand","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5073144179","display_name":"Jed W. Fahey","orcid":"https://orcid.org/0000-0002-2129-1834","observed_orcids":["https://orcid.org/0000-0002-2129-1834"]},"institutions":[{"id":"https://openalex.org/I145311948","display_name":"Johns Hopkins University","ror":"https://ror.org/00za53h95","country_code":"US","type":"education","lineage":["https://openalex.org/I145311948"]},{"id":"https://openalex.org/I2799853436","display_name":"Johns Hopkins Medicine","ror":"https://ror.org/037zgn354","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2799853436"]},{"id":"https://openalex.org/I7947594","display_name":"University of Maine","ror":"https://ror.org/01adr0w49","country_code":"US","type":"education","lineage":["https://openalex.org/I2802397601","https://openalex.org/I7947594"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jed W. Fahey","raw_affiliation_strings":["Department of Medicine, Physiology, Pharmacology & Therapeutics, Psychiatry & Behavioral Sciences, and iMIND Hopkins, School of Medicine Johns Hopkins University  Baltimore Maryland USA","Institute of Medicine University of Maine  Orono Maine USA"],"raw_orcid":"https://orcid.org/0000-0002-2129-1834","affiliations":[{"raw_affiliation_string":"Department of Medicine, Physiology, Pharmacology & Therapeutics, Psychiatry & Behavioral Sciences, and iMIND Hopkins, School of Medicine Johns Hopkins University  Baltimore Maryland USA","institution_ids":["https://openalex.org/I145311948","https://openalex.org/I2799853436"]},{"raw_affiliation_string":"Institute of Medicine University of Maine  Orono Maine USA","institution_ids":["https://openalex.org/I7947594"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5034759150","display_name":"Megan N.C. Grainger","orcid":"https://orcid.org/0000-0003-4272-6806","observed_orcids":["https://orcid.org/0000-0003-4272-6806"]},"institutions":[{"id":"https://openalex.org/I52179390","display_name":"University of Waikato","ror":"https://ror.org/013fsnh78","country_code":"NZ","type":"education","lineage":["https://openalex.org/I52179390"]}],"countries":["NZ"],"is_corresponding":true,"raw_author_name":"Megan N. C. Grainger","raw_affiliation_strings":["School of Science, Division of STEM The University of Waikato  Hamilton New Zealand"],"raw_orcid":"https://orcid.org/0000-0003-4272-6806","affiliations":[{"raw_affiliation_string":"School of Science, Division of STEM The University of Waikato  Hamilton New Zealand","institution_ids":["https://openalex.org/I52179390"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5034759150"],"corresponding_institution_ids":["https://openalex.org/I52179390"],"apc_list":{"value":3630,"currency":"USD","value_usd":3630},"apc_paid":{"value":3630,"currency":"USD","value_usd":3630},"fwci":0.0,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":{"value":0.68928445,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"14","issue":"10","first_page":"e72421","last_page":"e72421"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10909","display_name":"Edible Oils Quality and Analysis","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/1605","display_name":"Organic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10909","display_name":"Edible Oils Quality and Analysis","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/1605","display_name":"Organic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10035","display_name":"Phytochemicals and Antioxidant Activities","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2704","display_name":"Biochemistry (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10404","display_name":"Enzyme Catalysis and Immobilization","score":0.0,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/oleuropein-aglycone","display_name":"oleuropein aglycone","score":0.8889999985694885},{"id":"https://openalex.org/keywords/olive-leaves","display_name":"olive leaves","score":0.9350000023841858},{"id":"https://openalex.org/keywords/phenolic-compounds","display_name":"phenolic compounds","score":0.8169999718666077},{"id":"https://openalex.org/keywords/beta-glucosidase","display_name":"\u03b2-glucosidase","score":0.9129999876022339},{"id":"https://openalex.org/keywords/enzymatic-hydrolysis","display_name":"enzymatic hydrolysis","score":0.9300000071525574},{"id":"https://openalex.org/keywords/almond-milk","display_name":"almond milk","score":0.6790000200271606},{"id":"https://openalex.org/keywords/almond-flour","display_name":"almond flour","score":0.8799999952316284},{"id":"https://openalex.org/keywords/almond-meal","display_name":"almond meal","score":0.9110000133514404},{"id":"https://openalex.org/keywords/aqueous-extract","display_name":"aqueous extract","score":0.675000011920929},{"id":"https://openalex.org/keywords/secoiridoids","display_name":"secoiridoids","score":0.7179999947547913},{"id":"https://openalex.org/keywords/extra-virgin-olive-oil","display_name":"extra virgin olive oil","score":0.7400000095367432}],"concepts":[{"id":"https://openalex.org/C2777957096","wikidata":"https://www.wikidata.org/wiki/Q402625","display_name":"Oleuropein","level":3,"score":0.9986000061035156},{"id":"https://openalex.org/C2779396346","wikidata":"https://www.wikidata.org/wiki/Q394316","display_name":"Aglycone","level":3,"score":0.9664000272750854},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.8518000245094299},{"id":"https://openalex.org/C2775881703","wikidata":"https://www.wikidata.org/wiki/Q744577","display_name":"Hydroxytyrosol","level":4,"score":0.7038000226020813},{"id":"https://openalex.org/C31903555","wikidata":"https://www.wikidata.org/wiki/Q1637030","display_name":"Food science","level":1,"score":0.5568000078201294},{"id":"https://openalex.org/C2988377048","wikidata":"https://www.wikidata.org/wiki/Q93165","display_name":"Olive oil","level":2,"score":0.4918999969959259},{"id":"https://openalex.org/C2779005586","wikidata":"https://www.wikidata.org/wiki/Q7087231","display_name":"Olive leaf","level":2,"score":0.48750001192092896},{"id":"https://openalex.org/C94412978","wikidata":"https://www.wikidata.org/wiki/Q103135","display_name":"Hydrolysis","level":2,"score":0.4697999954223633},{"id":"https://openalex.org/C46328234","wikidata":"https://www.wikidata.org/wiki/Q1501465","display_name":"Organoleptic","level":2,"score":0.46480000019073486},{"id":"https://openalex.org/C2776344796","wikidata":"https://www.wikidata.org/wiki/Q155966","display_name":"Oleaceae","level":2,"score":0.45249998569488525},{"id":"https://openalex.org/C2781397471","wikidata":"https://www.wikidata.org/wiki/Q296910","display_name":"Olea","level":2,"score":0.41690000891685486},{"id":"https://openalex.org/C53270655","wikidata":"https://www.wikidata.org/wiki/Q5381536","display_name":"Enzymatic hydrolysis","level":3,"score":0.4032000005245209},{"id":"https://openalex.org/C43617362","wikidata":"https://www.wikidata.org/wiki/Q170050","display_name":"Chromatography","level":1,"score":0.36899998784065247},{"id":"https://openalex.org/C184651966","wikidata":"https://www.wikidata.org/wiki/Q906356","display_name":"Aqueous solution","level":2,"score":0.33899998664855957},{"id":"https://openalex.org/C2777728882","wikidata":"https://www.wikidata.org/wiki/Q407142","display_name":"Phenols","level":2,"score":0.33739998936653137},{"id":"https://openalex.org/C2779096019","wikidata":"https://www.wikidata.org/wiki/Q4739805","display_name":"Vegetable oil","level":2,"score":0.3305000066757202},{"id":"https://openalex.org/C188198153","wikidata":"https://www.wikidata.org/wiki/Q1613840","display_name":"Limiting","level":2,"score":0.31949999928474426},{"id":"https://openalex.org/C59822182","wikidata":"https://www.wikidata.org/wiki/Q441","display_name":"Botany","level":1,"score":0.2825999855995178},{"id":"https://openalex.org/C16281581","wikidata":"https://www.wikidata.org/wiki/Q874733","display_name":"Flavour","level":2,"score":0.2802000045776367},{"id":"https://openalex.org/C2993907526","wikidata":"https://www.wikidata.org/wiki/Q1259977","display_name":"Aqueous extract","level":2,"score":0.26269999146461487}],"mesh":[],"locations_count":3,"locations":[{"id":"doi:10.1002/fsn3.72421","doi":"https://doi.org/10.1002/fsn3.72421","is_oa":true,"landing_page_url":"https://doi.org/10.1002/fsn3.72421","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/fsn3.72421","source":{"id":"https://openalex.org/S2764587058","display_name":"Food Science & Nutrition","issn_l":"2048-7177","issn":["2048-7177"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","jufo-1","ki-jl-1","norway-1","poland-100","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Food Science & Nutrition","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:13694744","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC13694744/","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC13694744/pdf/FSN3-14-e72421.pdf","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Food Sci Nutr","raw_type":"Text"},{"id":"pmid:42927163","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/42927163","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Food science & nutrition","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.1002/fsn3.72421","doi":"https://doi.org/10.1002/fsn3.72421","is_oa":true,"landing_page_url":"https://doi.org/10.1002/fsn3.72421","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/fsn3.72421","source":{"id":"https://openalex.org/S2764587058","display_name":"Food Science & Nutrition","issn_l":"2048-7177","issn":["2048-7177"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","jufo-1","ki-jl-1","norway-1","poland-100","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Food Science & Nutrition","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/12","score":0.7811999917030334,"display_name":"Responsible consumption and production"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W7223464693.pdf","grobid_xml":"https://content.openalex.org/works/W7223464693.grobid-xml"},"referenced_works_count":51,"referenced_works":["https://openalex.org/W1174839022","https://openalex.org/W1876119972","https://openalex.org/W1980502026","https://openalex.org/W1990766989","https://openalex.org/W2001731791","https://openalex.org/W2003805854","https://openalex.org/W2004985722","https://openalex.org/W2006462593","https://openalex.org/W2014093552","https://openalex.org/W2017006111","https://openalex.org/W2026065943","https://openalex.org/W2053874078","https://openalex.org/W2073519247","https://openalex.org/W2103002506","https://openalex.org/W2149828455","https://openalex.org/W2260428028","https://openalex.org/W2260654140","https://openalex.org/W2319172607","https://openalex.org/W2330775953","https://openalex.org/W2743061906","https://openalex.org/W2750098455","https://openalex.org/W2767561178","https://openalex.org/W2785861020","https://openalex.org/W2901112932","https://openalex.org/W2918561444","https://openalex.org/W2927495432","https://openalex.org/W2945482058","https://openalex.org/W2967775669","https://openalex.org/W2972563901","https://openalex.org/W3000240068","https://openalex.org/W3006236989","https://openalex.org/W3009551732","https://openalex.org/W3027497533","https://openalex.org/W3037762241","https://openalex.org/W3044920299","https://openalex.org/W3046063438","https://openalex.org/W3048936444","https://openalex.org/W3091991021","https://openalex.org/W3119627417","https://openalex.org/W3123627425","https://openalex.org/W3169824267","https://openalex.org/W3186935786","https://openalex.org/W3211869032","https://openalex.org/W4200436870","https://openalex.org/W4221006086","https://openalex.org/W4224242773","https://openalex.org/W4296006451","https://openalex.org/W4308593374","https://openalex.org/W4311206019","https://openalex.org/W4312094887","https://openalex.org/W4318485588"],"related_works":["https://openalex.org/W7072056239","https://openalex.org/W4224271774","https://openalex.org/W2529232953","https://openalex.org/W4392935190","https://openalex.org/W2014093552","https://openalex.org/W2807388069","https://openalex.org/W3158463224","https://openalex.org/W4285793877","https://openalex.org/W2140013017","https://openalex.org/W6977332879"],"abstract_inverted_index":{"Oleuropein":[0,22],"is":[1,7,24],"present":[2],"in":[3,150],"olive":[4,33,54,79,113],"fruit":[5],"and":[6,19,92,117,126,153],"converted":[8],"during":[9],"olive-oil":[10,65],"manufacture":[11],"into":[12,81],"oleuropein":[13,90,131,148,175],"aglycone,":[14],"other":[15],"downstream":[16],"secoiridoid":[17],"derivatives,":[18],"phenolic":[20,28,61,74],"alcohols.":[21],"aglycone":[23,91,134,176],"among":[25],"the":[26,53,70,109,133,138,146,151,157,162,171,174,178,182,188,197],"major":[27],"constituents":[29],"of":[30,37,45,52,60,72,94,103,108,120,159,168,173],"extra":[31],"virgin":[32],"oil;":[34],"however,":[35],"concentrations":[36],"these":[38],"compounds":[39,62],"can":[40],"vary":[41],"substantially":[42],"between":[43],"batches":[44],"oil.":[46],"Olive":[47],"leaves,":[48],"an":[49,82,98],"oleuropein-rich":[50],"by-product":[51],"industry,":[55],"may":[56],"provide":[57],"a":[58],"source":[59,158],"for":[63],"targeted":[64],"enrichment.":[66],"This":[67],"study":[68],"investigated":[69],"prospect":[71],"extracting":[73],"compounds,":[75],"particularly":[76],"oleuropein,":[77],"from":[78,177],"leaves":[80,110,142],"aqueous":[83,115,179],"extract":[84,116,180],"followed":[85],"by":[86],"enzymatic":[87],"hydrolysis":[88,167],"to":[89,97,129,132,165,181],"assessment":[93],"its":[95],"transfer":[96,172],"oil":[99,183],"phase.":[100],"The":[101],"impact":[102],"parameters":[104],"such":[105],"as":[106,156],"dryness":[107],"when":[111],"making":[112],"leaf":[114],"different":[118],"sources":[119],"\u03b2-glucosidase":[121],"(almond":[122],"flour,":[123],"almond":[124,127,154],"meal,":[125],"milk)":[128],"hydrolyse":[130],"were":[135,195],"investigated.":[136],"Among":[137],"conditions":[139,189],"tested,":[140,190],"drying":[141],"at":[143],"70\u00b0C":[144],"produced":[145],"highest":[147],"concentration":[149],"extract,":[152],"milk":[155],"enzyme":[160],"was":[161,185],"best":[163],"combination":[164],"achieve":[166],"oleuropein.":[169],"However,":[170],"phase":[184],"inefficient":[186],"under":[187],"indicating":[191],"that":[192],"multiple":[193],"factors":[194],"limiting":[196],"mass":[198],"transfer.":[199]},"counts_by_year":[],"updated_date":"2026-11-08T12:12:28.789561","created_date":"2026-10-25T00:00:00"}