{"id":"https://openalex.org/W7223449795","doi":"https://doi.org/10.1186/s12884-026-10135-y","title":"Pregnancy outcomes in women with endometriosis-associated pelvic pain: an observational cohort study of natural and assisted conceptions","display_name":"Pregnancy outcomes in women with endometriosis-associated pelvic pain: an observational cohort study of natural and assisted conceptions","publication_year":2026,"publication_date":"2026-10-24","ids":{"openalex":"https://openalex.org/W7223449795","doi":"https://doi.org/10.1186/s12884-026-10135-y"},"language":"en","primary_location":{"id":"doi:10.1186/s12884-026-10135-y","doi":"https://doi.org/10.1186/s12884-026-10135-y","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s12884-026-10135-y","pdf_url":null,"source":{"id":"https://openalex.org/S123732490","display_name":"BMC Pregnancy and Childbirth","issn_l":"1471-2393","issn":["1471-2393"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Pregnancy and Childbirth","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","doaj"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://doi.org/10.1186/s12884-026-10135-y","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5100994867","display_name":"Yunyu Xu","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I197869895","display_name":"Anhui Medical University","ror":"https://ror.org/03xb04968","country_code":"CN","type":"education","lineage":["https://openalex.org/I197869895"]},{"id":"https://openalex.org/I4210136596","display_name":"First Affiliated Hospital of Anhui Medical University","ror":"https://ror.org/03t1yn780","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210136596"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yunyu Xu","raw_affiliation_strings":["Anhui Medical University, Hefei, Anhui Province, China","Center for Big Data and Population Health of IHM, the First Affiliated Hospital of Anhui Medical University, Hefei, Anhui Province, China","Department of Obstetrics and Gynecology, the First Affiliated Hospital of Anhui Medical University, Hefei, Anhui Province, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Anhui Medical University, Hefei, Anhui Province, China","institution_ids":["https://openalex.org/I197869895"]},{"raw_affiliation_string":"Center for Big Data and Population Health of IHM, the First Affiliated Hospital of Anhui Medical University, Hefei, Anhui Province, China","institution_ids":["https://openalex.org/I4210136596"]},{"raw_affiliation_string":"Department of Obstetrics and Gynecology, the First Affiliated Hospital of Anhui Medical University, Hefei, Anhui Province, China","institution_ids":["https://openalex.org/I4210136596"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5135203937","display_name":"Xiaoxue Deng","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I197869895","display_name":"Anhui Medical University","ror":"https://ror.org/03xb04968","country_code":"CN","type":"education","lineage":["https://openalex.org/I197869895"]},{"id":"https://openalex.org/I4210136596","display_name":"First Affiliated Hospital of Anhui Medical University","ror":"https://ror.org/03t1yn780","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210136596"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Xiaoxue Deng","raw_affiliation_strings":["Anhui Medical University, Hefei, Anhui Province, China","Department of Obstetrics and Gynecology, the First Affiliated Hospital of Anhui Medical University, Hefei, Anhui Province, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Anhui Medical University, Hefei, Anhui Province, China","institution_ids":["https://openalex.org/I197869895"]},{"raw_affiliation_string":"Department of Obstetrics and Gynecology, the First Affiliated Hospital of Anhui Medical University, Hefei, Anhui Province, China","institution_ids":["https://openalex.org/I4210136596"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5159383713","display_name":"Wanqing Li","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I197869895","display_name":"Anhui Medical University","ror":"https://ror.org/03xb04968","country_code":"CN","type":"education","lineage":["https://openalex.org/I197869895"]},{"id":"https://openalex.org/I4210136596","display_name":"First Affiliated Hospital of Anhui Medical University","ror":"https://ror.org/03t1yn780","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210136596"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Wanqing Li","raw_affiliation_strings":["Anhui Medical University, Hefei, Anhui Province, China","Department of Obstetrics and Gynecology, the First Affiliated Hospital of Anhui Medical University, Hefei, Anhui Province, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Anhui Medical University, Hefei, Anhui Province, China","institution_ids":["https://openalex.org/I197869895"]},{"raw_affiliation_string":"Department of Obstetrics and Gynecology, the First Affiliated Hospital of Anhui Medical University, Hefei, Anhui Province, China","institution_ids":["https://openalex.org/I4210136596"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5158534522","display_name":"Ye He","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210136596","display_name":"First Affiliated Hospital of Anhui Medical University","ror":"https://ror.org/03t1yn780","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210136596"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Ye He","raw_affiliation_strings":["Center for Big Data and Population Health of IHM, the First Affiliated Hospital of Anhui Medical University, Hefei, Anhui Province, China","Department of Obstetrics and Gynecology, the First Affiliated Hospital of Anhui Medical University, Hefei, Anhui Province, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Big Data and Population Health of IHM, the First Affiliated Hospital of Anhui Medical University, Hefei, Anhui Province, China","institution_ids":["https://openalex.org/I4210136596"]},{"raw_affiliation_string":"Department of Obstetrics and Gynecology, the First Affiliated Hospital of Anhui Medical University, Hefei, Anhui Province, China","institution_ids":["https://openalex.org/I4210136596"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5091394061","display_name":"Youyan Fang","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210136596","display_name":"First Affiliated Hospital of Anhui Medical University","ror":"https://ror.org/03t1yn780","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210136596"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Youyan Fang","raw_affiliation_strings":["Department of Obstetrics and Gynecology, the First Affiliated Hospital of Anhui Medical University, Hefei, Anhui Province, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Obstetrics and Gynecology, the First Affiliated Hospital of Anhui Medical University, Hefei, Anhui Province, China","institution_ids":["https://openalex.org/I4210136596"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5158518090","display_name":"Zhaolian Wei","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210136596","display_name":"First Affiliated Hospital of Anhui Medical University","ror":"https://ror.org/03t1yn780","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210136596"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Zhaolian Wei","raw_affiliation_strings":["Center for Big Data and Population Health of IHM, the First Affiliated Hospital of Anhui Medical University, Hefei, Anhui Province, China","Department of Obstetrics and Gynecology, the First Affiliated Hospital of Anhui Medical University, Hefei, Anhui Province, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Big Data and Population Health of IHM, the First Affiliated Hospital of Anhui Medical University, Hefei, Anhui Province, China","institution_ids":["https://openalex.org/I4210136596"]},{"raw_affiliation_string":"Department of Obstetrics and Gynecology, the First Affiliated Hospital of Anhui Medical University, Hefei, Anhui Province, China","institution_ids":["https://openalex.org/I4210136596"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5158518090"],"corresponding_institution_ids":["https://openalex.org/I4210136596"],"apc_list":{"value":3290,"currency":"USD","value_usd":3290},"apc_paid":{"value":3290,"currency":"USD","value_usd":3290},"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.88265622,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10935","display_name":"Endometriosis Research and Treatment","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2743","display_name":"Reproductive Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10935","display_name":"Endometriosis Research and Treatment","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2743","display_name":"Reproductive Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12096","display_name":"Ectopic Pregnancy Diagnosis and Management","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2739","display_name":"Public Health, Environmental and Occupational Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11156","display_name":"Reproductive Health and Technologies","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2743","display_name":"Reproductive Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/endometriosis","display_name":"endometriosis","score":0.9950000047683716},{"id":"https://openalex.org/keywords/pelvic-pain","display_name":"pelvic pain","score":0.9800000190734863},{"id":"https://openalex.org/keywords/pregnancy-outcomes","display_name":"pregnancy outcomes","score":0.9079999923706055},{"id":"https://openalex.org/keywords/live-birth","display_name":"live birth","score":0.972000002861023},{"id":"https://openalex.org/keywords/assisted-reproductive-technology","display_name":"assisted reproduction","score":0.9369999766349792},{"id":"https://openalex.org/keywords/spontaneous-pregnancy","display_name":"spontaneous conception","score":0.9769999980926514},{"id":"https://openalex.org/keywords/placenta-accreta-spectrum","display_name":"placenta accreta spectrum","score":0.8560000061988831},{"id":"https://openalex.org/keywords/pregnancy-complications","display_name":"pregnancy complications","score":0.9779999852180481},{"id":"https://openalex.org/keywords/pain-intensity","display_name":"pain intensity","score":0.7900000214576721}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9259999990463257},{"id":"https://openalex.org/C2780136519","wikidata":"https://www.wikidata.org/wiki/Q7161805","display_name":"Pelvic pain","level":2,"score":0.707099974155426},{"id":"https://openalex.org/C201903717","wikidata":"https://www.wikidata.org/wiki/Q1778788","display_name":"Cohort study","level":2,"score":0.6363000273704529},{"id":"https://openalex.org/C23131810","wikidata":"https://www.wikidata.org/wiki/Q818574","display_name":"Observational study","level":2,"score":0.6360999941825867},{"id":"https://openalex.org/C2776210078","wikidata":"https://www.wikidata.org/wiki/Q351870","display_name":"Reproductive medicine","level":3,"score":0.6353999972343445},{"id":"https://openalex.org/C131872663","wikidata":"https://www.wikidata.org/wiki/Q5284418","display_name":"Obstetrics","level":1,"score":0.6155999898910522},{"id":"https://openalex.org/C61511704","wikidata":"https://www.wikidata.org/wiki/Q1671857","display_name":"Incidence (geometry)","level":2,"score":0.5906999707221985},{"id":"https://openalex.org/C2779234561","wikidata":"https://www.wikidata.org/wiki/Q11995","display_name":"Pregnancy","level":2,"score":0.546999990940094},{"id":"https://openalex.org/C151956035","wikidata":"https://www.wikidata.org/wiki/Q1132755","display_name":"Logistic regression","level":2,"score":0.4742000102996826},{"id":"https://openalex.org/C2778279030","wikidata":"https://www.wikidata.org/wiki/Q1543380","display_name":"Live birth","level":3,"score":0.4189000129699707},{"id":"https://openalex.org/C72563966","wikidata":"https://www.wikidata.org/wiki/Q1303415","display_name":"Cohort","level":2,"score":0.4140999913215637},{"id":"https://openalex.org/C2779116671","wikidata":"https://www.wikidata.org/wiki/Q517856","display_name":"Placenta accreta","level":5,"score":0.4041000008583069},{"id":"https://openalex.org/C500014431","wikidata":"https://www.wikidata.org/wiki/Q25862","display_name":"Assisted reproductive technology","level":4,"score":0.37709999084472656},{"id":"https://openalex.org/C2779522080","wikidata":"https://www.wikidata.org/wiki/Q205764","display_name":"Endometriosis","level":2,"score":0.37529999017715454},{"id":"https://openalex.org/C188816634","wikidata":"https://www.wikidata.org/wiki/Q2113324","display_name":"Prospective cohort study","level":2,"score":0.3698999881744385},{"id":"https://openalex.org/C29456083","wikidata":"https://www.wikidata.org/wiki/Q1221899","display_name":"Gynecology","level":1,"score":0.36250001192092896},{"id":"https://openalex.org/C2776352029","wikidata":"https://www.wikidata.org/wiki/Q4686351","display_name":"Advanced maternal age","level":4,"score":0.3474000096321106},{"id":"https://openalex.org/C2779250420","wikidata":"https://www.wikidata.org/wiki/Q2071048","display_name":"Antepartum haemorrhage","level":4,"score":0.31859999895095825},{"id":"https://openalex.org/C205545832","wikidata":"https://www.wikidata.org/wiki/Q17156455","display_name":"Young adult","level":2,"score":0.3154999911785126},{"id":"https://openalex.org/C142052008","wikidata":"https://www.wikidata.org/wiki/Q954027","display_name":"Cross-sectional study","level":2,"score":0.2944999933242798},{"id":"https://openalex.org/C2777688143","wikidata":"https://www.wikidata.org/wiki/Q179399","display_name":"Infertility","level":3,"score":0.28760001063346863},{"id":"https://openalex.org/C2908647359","wikidata":"https://www.wikidata.org/wiki/Q2625603","display_name":"Population","level":2,"score":0.28459998965263367},{"id":"https://openalex.org/C167135981","wikidata":"https://www.wikidata.org/wiki/Q2146302","display_name":"Retrospective cohort study","level":2,"score":0.27869999408721924},{"id":"https://openalex.org/C2780340734","wikidata":"https://www.wikidata.org/wiki/Q7579057","display_name":"Spontaneous conception","level":4,"score":0.27459999918937683},{"id":"https://openalex.org/C3018745865","wikidata":"https://www.wikidata.org/wiki/Q749115","display_name":"Postpartum period","level":3,"score":0.2632000148296356},{"id":"https://openalex.org/C121752807","wikidata":"https://www.wikidata.org/wiki/Q1981388","display_name":"Reproductive health","level":3,"score":0.26100000739097595},{"id":"https://openalex.org/C146304588","wikidata":"https://www.wikidata.org/wiki/Q961652","display_name":"Case-control study","level":2,"score":0.25200000405311584},{"id":"https://openalex.org/C14184104","wikidata":"https://www.wikidata.org/wiki/Q1362526","display_name":"Visual analogue scale","level":2,"score":0.25130000710487366}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1186/s12884-026-10135-y","doi":"https://doi.org/10.1186/s12884-026-10135-y","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s12884-026-10135-y","pdf_url":null,"source":{"id":"https://openalex.org/S123732490","display_name":"BMC Pregnancy and Childbirth","issn_l":"1471-2393","issn":["1471-2393"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Pregnancy and Childbirth","raw_type":"journal-article"}],"best_oa_location":{"id":"doi:10.1186/s12884-026-10135-y","doi":"https://doi.org/10.1186/s12884-026-10135-y","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s12884-026-10135-y","pdf_url":null,"source":{"id":"https://openalex.org/S123732490","display_name":"BMC Pregnancy and Childbirth","issn_l":"1471-2393","issn":["1471-2393"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Pregnancy and Childbirth","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":1.0,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W4390154016","https://openalex.org/W4387395998","https://openalex.org/W2211503579","https://openalex.org/W2889996896","https://openalex.org/W7142070571","https://openalex.org/W2548132309","https://openalex.org/W3197614877","https://openalex.org/W4396903092","https://openalex.org/W2569100509","https://openalex.org/W4388901385"],"abstract_inverted_index":{"Pelvic":[0],"pain":[1,40,86,102,117,141,178,184,218,243],"is":[2],"a":[3,90,165,194,237,245],"cardinal":[4],"symptom":[5],"of":[6,37,169,197,248],"endometriosis,":[7,50,215],"but":[8,257],"whether":[9,16,54],"it":[10],"independently":[11,144,221],"predicts":[12],"reproductive":[13,25,120],"outcomes,":[14,121],"and":[15,23,44,51,119,199,244,264],"this":[17,62,189,258],"association":[18,36,115,239],"differs":[19],"between":[20,116,240],"spontaneous":[21,209,231],"conception":[22,59,80,210,232],"assisted":[24],"technology":[26],"(ART),":[27],"remains":[28],"unclear.":[29],"This":[30],"study":[31],"aimed":[32],"to":[33,52,76,111],"evaluate":[34],"the":[35,113,126,159,208,228,254],"moderate-to-severe":[38,177,216],"pelvic":[39,217],"with":[41,49,72,122,146,176,182,214,223],"live":[42,123,147,224],"birth":[43,124,148,225],"obstetric":[45],"complications":[46,130],"in":[47,98,149,207,226,253],"women":[48,71,175,213],"examine":[53],"these":[55],"associations":[56],"differed":[57],"by":[58,79],"pathway.":[60,211,233],"In":[61,158,212],"observational":[63],"cohort":[64],"study,":[65],"we":[66],"analyzed":[67,132],"data":[68],"from":[69],"1,063":[70],"endometriosis":[73],"who":[74],"intended":[75],"conceive,":[77],"stratified":[78],"pathway":[81,151],"(ART":[82],"vs.":[83,186],"spontaneous).":[84],"Moderate-to-severe":[85,140],"was":[87,142,191,205,219],"defined":[88],"as":[89,125,133,266],"visual":[91],"analog":[92],"scale":[93],"(VAS)":[94],"score":[95],"\u2265":[96],"4":[97],"at":[99],"least":[100],"one":[101],"domain.":[103],"Pathway-specific":[104],"multivariable":[105],"logistic":[106],"regression":[107],"models":[108],"were":[109,131],"used":[110],"assess":[112],"independent":[114],"severity":[118],"primary":[127],"outcome.":[128],"Obstetric":[129],"secondary":[134],"exploratory":[135,162],"outcomes":[136],"using":[137],"unadjusted":[138,200],"comparisons.":[139,201],"not":[143,220],"associated":[145,222],"either":[150,227],"after":[152],"adjustment":[153],"for":[154],"clinically":[155],"relevant":[156],"confounders.":[157],"ART":[160,229,255],"pathway,":[161,256],"analyses":[163],"showed":[164],"higher":[166,246],"observed":[167,206],"incidence":[168,247],"placenta":[170,249],"accreta":[171,250],"spectrum":[172,251],"disorders":[173,252],"among":[174,180],"than":[179],"those":[181],"no/mild":[183],"(9.0%":[185],"3.2%).":[187],"However,":[188],"finding":[190],"based":[192],"on":[193],"small":[195],"number":[196],"events":[198],"No":[202],"comparable":[203],"pattern":[204],"or":[230],"Exploratory":[234],"findings":[235],"suggested":[236],"possible":[238],"more":[241],"severe":[242],"observation":[259],"should":[260],"be":[261],"interpreted":[262],"cautiously":[263],"regarded":[265],"hypothesis-generating.":[267]},"counts_by_year":[],"updated_date":"2026-10-27T15:51:10.671819","created_date":"2026-10-25T00:00:00"}