{"id":"https://openalex.org/W7223311249","doi":"https://doi.org/10.1038/s41467-026-78562-1","title":"Tom70\u2013mediated mitochondria\u2013nuclear envelope contacts regulate nuclear pore complex inheritance during gametogenesis","display_name":"Tom70\u2013mediated mitochondria\u2013nuclear envelope contacts regulate nuclear pore complex inheritance during gametogenesis","publication_year":2026,"publication_date":"2026-10-23","ids":{"openalex":"https://openalex.org/W7223311249","doi":"https://doi.org/10.1038/s41467-026-78562-1"},"language":"en","primary_location":{"id":"doi:10.1038/s41467-026-78562-1","doi":"https://doi.org/10.1038/s41467-026-78562-1","is_oa":true,"landing_page_url":"https://doi.org/10.1038/s41467-026-78562-1","pdf_url":"https://www.nature.com/articles/s41467-026-78562-1_reference.pdf","source":{"id":"https://openalex.org/S64187185","display_name":"Nature Communications","issn_l":"2041-1723","issn":["2041-1723"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","doaj","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","oarl","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319908","host_organization_name":"Nature Portfolio","host_organization_lineage":["https://openalex.org/P4310319908","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Nature Portfolio","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nature Communications","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://www.nature.com/articles/s41467-026-78562-1_reference.pdf","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5047880671","display_name":"Cyrus T. Ruediger","orcid":"https://orcid.org/0000-0001-6054-3806","observed_orcids":["https://orcid.org/0000-0001-6054-3806"]},"institutions":[{"id":"https://openalex.org/I95457486","display_name":"University of California, Berkeley","ror":"https://ror.org/01an7q238","country_code":"US","type":"education","lineage":["https://openalex.org/I95457486"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Cyrus T. Ruediger","raw_affiliation_strings":["Department of Molecular and Cell Biology, University of California, Berkeley, CA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Molecular and Cell Biology, University of California, Berkeley, CA, USA","institution_ids":["https://openalex.org/I95457486"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5106341788","display_name":"Benjamin S. Styler","orcid":"https://orcid.org/0000-0002-0458-8230","observed_orcids":["https://orcid.org/0000-0002-0458-8230"]},"institutions":[{"id":"https://openalex.org/I95457486","display_name":"University of California, Berkeley","ror":"https://ror.org/01an7q238","country_code":"US","type":"education","lineage":["https://openalex.org/I95457486"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Benjamin S. Styler","raw_affiliation_strings":["Department of Molecular and Cell Biology, University of California, Berkeley, CA, USA"],"raw_orcid":"https://orcid.org/0000-0002-0458-8230","affiliations":[{"raw_affiliation_string":"Department of Molecular and Cell Biology, University of California, Berkeley, CA, USA","institution_ids":["https://openalex.org/I95457486"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5091595841","display_name":"Eric M. Sawyer","orcid":"https://orcid.org/0000-0003-1160-3838","observed_orcids":["https://orcid.org/0000-0003-1160-3838"]},"institutions":[{"id":"https://openalex.org/I95457486","display_name":"University of California, Berkeley","ror":"https://ror.org/01an7q238","country_code":"US","type":"education","lineage":["https://openalex.org/I95457486"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Eric M. Sawyer","raw_affiliation_strings":["Department of Molecular and Cell Biology, University of California, Berkeley, CA, USA"],"raw_orcid":"https://orcid.org/0000-0003-1160-3838","affiliations":[{"raw_affiliation_string":"Department of Molecular and Cell Biology, University of California, Berkeley, CA, USA","institution_ids":["https://openalex.org/I95457486"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5090474142","display_name":"Silvan Spiri","orcid":"https://orcid.org/0000-0002-7124-3056","observed_orcids":["https://orcid.org/0000-0002-7124-3056"]},"institutions":[{"id":"https://openalex.org/I95457486","display_name":"University of California, Berkeley","ror":"https://ror.org/01an7q238","country_code":"US","type":"education","lineage":["https://openalex.org/I95457486"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Silvan Spiri","raw_affiliation_strings":["Department of Molecular and Cell Biology, University of California, Berkeley, CA, USA"],"raw_orcid":"https://orcid.org/0000-0002-7124-3056","affiliations":[{"raw_affiliation_string":"Department of Molecular and Cell Biology, University of California, Berkeley, CA, USA","institution_ids":["https://openalex.org/I95457486"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5005435988","display_name":"Grant A. King","orcid":"https://orcid.org/0000-0001-9854-3174","observed_orcids":["https://orcid.org/0000-0001-9854-3174"]},"institutions":[{"id":"https://openalex.org/I95457486","display_name":"University of California, Berkeley","ror":"https://ror.org/01an7q238","country_code":"US","type":"education","lineage":["https://openalex.org/I95457486"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Grant A. King","raw_affiliation_strings":["Department of Molecular and Cell Biology, University of California, Berkeley, CA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Molecular and Cell Biology, University of California, Berkeley, CA, USA","institution_ids":["https://openalex.org/I95457486"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5046942095","display_name":"Madison E. Walsh","orcid":"https://orcid.org/0000-0002-1082-9678","observed_orcids":["https://orcid.org/0000-0002-1082-9678"]},"institutions":[{"id":"https://openalex.org/I95457486","display_name":"University of California, Berkeley","ror":"https://ror.org/01an7q238","country_code":"US","type":"education","lineage":["https://openalex.org/I95457486"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Madison E. Walsh","raw_affiliation_strings":["Department of Molecular and Cell Biology, University of California, Berkeley, CA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Molecular and Cell Biology, University of California, Berkeley, CA, USA","institution_ids":["https://openalex.org/I95457486"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5058972457","display_name":"Gloria Ann Brar","orcid":"https://orcid.org/0000-0002-8560-9581","observed_orcids":["https://orcid.org/0000-0002-8560-9581"]},"institutions":[{"id":"https://openalex.org/I103922791","display_name":"QB3","ror":"https://ror.org/04n1n3n22","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I103922791","https://openalex.org/I180670191","https://openalex.org/I185103710","https://openalex.org/I95457486"]},{"id":"https://openalex.org/I95457486","display_name":"University of California, Berkeley","ror":"https://ror.org/01an7q238","country_code":"US","type":"education","lineage":["https://openalex.org/I95457486"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Gloria A. Brar","raw_affiliation_strings":["California Institute for Quantitative Biosciences (QB3), University of California, Berkeley, CA, USA","Center for Computational Biology, University of California, Berkeley, CA, USA","Department of Molecular and Cell Biology, University of California, Berkeley, CA, USA"],"raw_orcid":"https://orcid.org/0000-0002-8560-9581","affiliations":[{"raw_affiliation_string":"California Institute for Quantitative Biosciences (QB3), University of California, Berkeley, CA, USA","institution_ids":["https://openalex.org/I103922791","https://openalex.org/I95457486"]},{"raw_affiliation_string":"Center for Computational Biology, University of California, Berkeley, CA, USA","institution_ids":["https://openalex.org/I95457486"]},{"raw_affiliation_string":"Department of Molecular and Cell Biology, University of California, Berkeley, CA, USA","institution_ids":["https://openalex.org/I95457486"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5072470315","display_name":"Danielle M. Jorgens","orcid":"https://orcid.org/0000-0002-7143-0118","observed_orcids":["https://orcid.org/0000-0002-7143-0118"]},"institutions":[{"id":"https://openalex.org/I95457486","display_name":"University of California, Berkeley","ror":"https://ror.org/01an7q238","country_code":"US","type":"education","lineage":["https://openalex.org/I95457486"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Danielle M. Jorgens","raw_affiliation_strings":["Electron Microscope Lab, University of California, Berkeley, CA, USA"],"raw_orcid":"https://orcid.org/0000-0002-7143-0118","affiliations":[{"raw_affiliation_string":"Electron Microscope Lab, University of California, Berkeley, CA, USA","institution_ids":["https://openalex.org/I95457486"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5051343849","display_name":"El\u00e7in \u00dcnal","orcid":"https://orcid.org/0000-0002-6768-609X","observed_orcids":["https://orcid.org/0000-0002-6768-609X"]},"institutions":[{"id":"https://openalex.org/I103922791","display_name":"QB3","ror":"https://ror.org/04n1n3n22","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I103922791","https://openalex.org/I180670191","https://openalex.org/I185103710","https://openalex.org/I95457486"]},{"id":"https://openalex.org/I95457486","display_name":"University of California, Berkeley","ror":"https://ror.org/01an7q238","country_code":"US","type":"education","lineage":["https://openalex.org/I95457486"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"El\u00e7in \u00dcnal","raw_affiliation_strings":["California Institute for Quantitative Biosciences (QB3), University of California, Berkeley, CA, USA","Center for Computational Biology, University of California, Berkeley, CA, USA","Department of Molecular and Cell Biology, University of California, Berkeley, CA, USA"],"raw_orcid":"https://orcid.org/0000-0002-6768-609X","affiliations":[{"raw_affiliation_string":"California Institute for Quantitative Biosciences (QB3), University of California, Berkeley, CA, USA","institution_ids":["https://openalex.org/I103922791","https://openalex.org/I95457486"]},{"raw_affiliation_string":"Center for Computational Biology, University of California, Berkeley, CA, USA","institution_ids":["https://openalex.org/I95457486"]},{"raw_affiliation_string":"Department of Molecular and Cell Biology, University of California, Berkeley, CA, USA","institution_ids":["https://openalex.org/I95457486"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5051343849"],"corresponding_institution_ids":["https://openalex.org/I103922791","https://openalex.org/I95457486"],"apc_list":{"value":6990,"currency":"USD","value_usd":6990},"apc_paid":{"value":6990,"currency":"USD","value_usd":6990},"fwci":0.0,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":{"value":0.68658854,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11841","display_name":"Nuclear Structure and Function","score":0.9779999852180481,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11841","display_name":"Nuclear Structure and Function","score":0.9779999852180481,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10301","display_name":"Mitochondrial Function and Pathology","score":0.005200000014156103,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10492","display_name":"Microtubule and mitosis dynamics","score":0.0034000000450760126,"subfield":{"id":"https://openalex.org/subfields/1307","display_name":"Cell Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/tom70","display_name":"Tom70","score":0.9980000257492065},{"id":"https://openalex.org/keywords/gametogenesis","display_name":"gametogenesis","score":0.7850000262260437},{"id":"https://openalex.org/keywords/meiosis-ii","display_name":"meiosis II","score":0.6940000057220459},{"id":"https://openalex.org/keywords/nuclear-quality-control","display_name":"nuclear quality control","score":0.7200000286102295},{"id":"https://openalex.org/keywords/saccharomyces-cerevisiae","display_name":"Saccharomyces cerevisiae","score":0.9139999747276306}],"concepts":[{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.6801999807357788},{"id":"https://openalex.org/C126725582","wikidata":"https://www.wikidata.org/wiki/Q30679","display_name":"Nuclear pore","level":3,"score":0.6586999893188477},{"id":"https://openalex.org/C39297687","wikidata":"https://www.wikidata.org/wiki/Q1410510","display_name":"Gametogenesis","level":4,"score":0.5770999789237976},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.5465999841690063},{"id":"https://openalex.org/C168240541","wikidata":"https://www.wikidata.org/wiki/Q45948","display_name":"Organelle","level":2,"score":0.5076000094413757},{"id":"https://openalex.org/C148196450","wikidata":"https://www.wikidata.org/wiki/Q21100485","display_name":"Meiosis","level":3,"score":0.4968999922275543},{"id":"https://openalex.org/C2777576037","wikidata":"https://www.wikidata.org/wiki/Q719725","display_name":"Saccharomyces cerevisiae","level":3,"score":0.4950000047683716},{"id":"https://openalex.org/C6929976","wikidata":"https://www.wikidata.org/wiki/Q3771881","display_name":"Regulator","level":3,"score":0.47589999437332153},{"id":"https://openalex.org/C2776803348","wikidata":"https://www.wikidata.org/wiki/Q211050","display_name":"Gamete","level":3,"score":0.43470001220703125},{"id":"https://openalex.org/C28859421","wikidata":"https://www.wikidata.org/wiki/Q39572","display_name":"Mitochondrion","level":2,"score":0.4169999957084656},{"id":"https://openalex.org/C110455231","wikidata":"https://www.wikidata.org/wiki/Q897788","display_name":"Compartmentalization (fire protection)","level":3,"score":0.3905999958515167},{"id":"https://openalex.org/C68556195","wikidata":"https://www.wikidata.org/wiki/Q3571630","display_name":"Nucleoporin","level":5,"score":0.35690000653266907},{"id":"https://openalex.org/C93304396","wikidata":"https://www.wikidata.org/wiki/Q14763008","display_name":"Mitosis","level":2,"score":0.35249999165534973},{"id":"https://openalex.org/C203635412","wikidata":"https://www.wikidata.org/wiki/Q17007432","display_name":"Compartment (ship)","level":2,"score":0.34929999709129333},{"id":"https://openalex.org/C2780114586","wikidata":"https://www.wikidata.org/wiki/Q40260","display_name":"Cell nucleus","level":3,"score":0.3425999879837036},{"id":"https://openalex.org/C20750100","wikidata":"https://www.wikidata.org/wiki/Q7068120","display_name":"Nuclear gene","level":4,"score":0.3327000141143799},{"id":"https://openalex.org/C29512474","wikidata":"https://www.wikidata.org/wiki/Q16860021","display_name":"Nuclear protein","level":4,"score":0.3255999982357025},{"id":"https://openalex.org/C163950672","wikidata":"https://www.wikidata.org/wiki/Q14905375","display_name":"mitochondrial fusion","level":4,"score":0.3100000023841858},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.30250000953674316},{"id":"https://openalex.org/C59157529","wikidata":"https://www.wikidata.org/wiki/Q994741","display_name":"Nuclear transport","level":4,"score":0.29829999804496765},{"id":"https://openalex.org/C2779324830","wikidata":"https://www.wikidata.org/wiki/Q1806192","display_name":"Mitophagy","level":4,"score":0.2957000136375427},{"id":"https://openalex.org/C49805395","wikidata":"https://www.wikidata.org/wiki/Q910966","display_name":"Nuclear localization sequence","level":3,"score":0.2865999937057495},{"id":"https://openalex.org/C65871279","wikidata":"https://www.wikidata.org/wiki/Q42884945","display_name":"Inner membrane","level":3,"score":0.28610000014305115},{"id":"https://openalex.org/C2777166614","wikidata":"https://www.wikidata.org/wiki/Q1198419","display_name":"Tetrahymena","level":2,"score":0.27799999713897705},{"id":"https://openalex.org/C2776519988","wikidata":"https://www.wikidata.org/wiki/Q1317935","display_name":"Schizosaccharomyces","level":5,"score":0.27390000224113464},{"id":"https://openalex.org/C179093185","wikidata":"https://www.wikidata.org/wiki/Q424506","display_name":"Lamin","level":3,"score":0.2702000141143799},{"id":"https://openalex.org/C501734568","wikidata":"https://www.wikidata.org/wiki/Q42918","display_name":"Mutation","level":3,"score":0.2689000070095062},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.26739999651908875},{"id":"https://openalex.org/C10879258","wikidata":"https://www.wikidata.org/wiki/Q76826611","display_name":"RNase P","level":4,"score":0.26489999890327454},{"id":"https://openalex.org/C2777896290","wikidata":"https://www.wikidata.org/wiki/Q465608","display_name":"Nuclear membrane","level":3,"score":0.25060001015663147},{"id":"https://openalex.org/C65155139","wikidata":"https://www.wikidata.org/wiki/Q5380912","display_name":"Envelope (radar)","level":3,"score":0.25040000677108765}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1038/s41467-026-78562-1","doi":"https://doi.org/10.1038/s41467-026-78562-1","is_oa":true,"landing_page_url":"https://doi.org/10.1038/s41467-026-78562-1","pdf_url":"https://www.nature.com/articles/s41467-026-78562-1_reference.pdf","source":{"id":"https://openalex.org/S64187185","display_name":"Nature Communications","issn_l":"2041-1723","issn":["2041-1723"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","doaj","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","oarl","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319908","host_organization_name":"Nature Portfolio","host_organization_lineage":["https://openalex.org/P4310319908","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Nature Portfolio","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nature Communications","raw_type":"journal-article"}],"best_oa_location":{"id":"doi:10.1038/s41467-026-78562-1","doi":"https://doi.org/10.1038/s41467-026-78562-1","is_oa":true,"landing_page_url":"https://doi.org/10.1038/s41467-026-78562-1","pdf_url":"https://www.nature.com/articles/s41467-026-78562-1_reference.pdf","source":{"id":"https://openalex.org/S64187185","display_name":"Nature Communications","issn_l":"2041-1723","issn":["2041-1723"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","doaj","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","oarl","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319908","host_organization_name":"Nature Portfolio","host_organization_lineage":["https://openalex.org/P4310319908","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Nature Portfolio","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nature Communications","raw_type":"journal-article"},"sustainable_development_goals":[],"study_designs":[],"awards":[{"id":"https://openalex.org/G2465514544","display_name":"Graduate Research Fellowship Program","funder_award_id":"1106400","funder_id":"https://openalex.org/F4320306076","funder_display_name":"National Science Foundation"},{"id":"https://openalex.org/G2966665750","display_name":"Graduate Research Fellowship Program (GRFP)","funder_award_id":"1752814","funder_id":"https://openalex.org/F4320306076","funder_display_name":"National Science Foundation"},{"id":"https://openalex.org/G3339040648","display_name":null,"funder_award_id":"DGE 1106400","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G5415523653","display_name":null,"funder_award_id":"DGE 1106400","funder_id":"https://openalex.org/F4320320924","funder_display_name":"Schweizerischer Nationalfonds zur F\u00f6rderung der Wissenschaftlichen Forschung"},{"id":"https://openalex.org/G6852334964","display_name":"Graduate Research Fellowship Program (GRFP)","funder_award_id":"2146752","funder_id":"https://openalex.org/F4320306076","funder_display_name":"National Science Foundation"},{"id":"https://openalex.org/G718078759","display_name":"The Molecular Basis of Cell Function","funder_award_id":"T32GM007232","funder_id":"https://openalex.org/F4320337354","funder_display_name":"National Institute of General Medical Sciences"},{"id":"https://openalex.org/G9000873219","display_name":"Illuminating the gene regulatory strategies underlying yeast meiosis and beyond","funder_award_id":"R35GM134886","funder_id":"https://openalex.org/F4320337354","funder_display_name":"National Institute of General Medical Sciences"}],"funders":[{"id":"https://openalex.org/F4320306076","display_name":"National Science Foundation","ror":"https://ror.org/021nxhr62"},{"id":"https://openalex.org/F4320320924","display_name":"Schweizerischer Nationalfonds zur F\u00f6rderung der Wissenschaftlichen Forschung","ror":"https://ror.org/00yjd3n13"},{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337337","display_name":"National Institute on Aging","ror":"https://ror.org/049v75w11"},{"id":"https://openalex.org/F4320337354","display_name":"National Institute of General Medical Sciences","ror":"https://ror.org/04q48ey07"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W7223311249.pdf","grobid_xml":"https://content.openalex.org/works/W7223311249.grobid-xml"},"referenced_works_count":3,"referenced_works":["https://openalex.org/W4214861448","https://openalex.org/W4388565585","https://openalex.org/W7214793562"],"related_works":["https://openalex.org/W3174071665","https://openalex.org/W7095518335","https://openalex.org/W3206102574","https://openalex.org/W4392595243","https://openalex.org/W2036424075","https://openalex.org/W4220904407","https://openalex.org/W3084409472","https://openalex.org/W1994005262","https://openalex.org/W2397033814","https://openalex.org/W7017921514"],"abstract_inverted_index":{"Abstract":[0],"Gametogenesis":[1,24],"rejuvenates":[2],"the":[3,23,37,54,68,97,102,131],"cellular":[4],"lineage":[5],"and":[6,64,81],"excludes":[7],"senescence-associated":[8,62],"factors":[9],"from":[10,32],"gametes.":[11,33],"In":[12],"Saccharomyces":[13],"cerevisiae":[14],",":[15],"this":[16],"involves":[17],"sequestration":[18,55],"of":[19,47,51,56,74,109],"nuclear":[20,57,103,132,137,148],"constituents":[21],"into":[22,67],"Uninherited":[25],"Nuclear":[26],"Compartment":[27],"(GUNC),":[28],"which":[29],"is":[30],"excluded":[31],"Here":[34],"we":[35],"identify":[36],"conserved":[38],"mitochondrial":[39,79],"import":[40,80],"receptor":[41],"Tom70":[42,94],"as":[43],"a":[44,84,123],"key":[45],"regulator":[46],"GUNC-mediated":[48],"exclusion.":[49],"Loss":[50,108],"TOM70":[52],"disrupts":[53],"pore":[58],"complexes,":[59],"but":[60],"not":[61],"aggregates":[63],"nucleolar":[65],"components,":[66],"GUNC.":[69],"Tom70\u2019s":[70],"role":[71],"appears":[72],"independent":[73],"its":[75],"canonical":[76],"function":[77],"in":[78],"instead":[82],"reflects":[83],"meiosis-specific":[85],"requirement":[86],"for":[87],"mitochondria-nuclear":[88],"envelope":[89,104,133],"tethering.":[90],"During":[91],"meiosis":[92],"II,":[93],"concentrates":[95],"around":[96],"GUNC,":[98],"where":[99],"it":[100],"recruits":[101],"tethering":[105,118],"protein":[106],"Cnm1.":[107],"CNM1":[110],"partially":[111],"phenocopies":[112],"tom70":[113],"\u2206,":[114],"consistent":[115],"with":[116,147],"parallel":[117],"interactions.":[119],"These":[120],"findings":[121],"uncover":[122],"previously":[124],"unrecognized":[125],"organelle":[126,144],"contact-dependent":[127],"pathway":[128],"that":[129],"remodels":[130],"to":[134,151],"support":[135],"selective":[136],"inheritance.":[138],"More":[139],"broadly,":[140],"they":[141],"highlight":[142],"how":[143],"contacts":[145],"integrate":[146],"quality":[149],"control":[150],"safeguard":[152],"gamete":[153],"integrity.":[154]},"counts_by_year":[],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2026-10-24T00:00:00"}