{"id":"https://openalex.org/W7223248397","doi":"https://doi.org/10.1093/ehjopen/oeag181","title":"One-minute heart rate recovery and clinical outcomes in transthyretin cardiac amyloidosis: incremental model fit beyond conventional CPET indices","display_name":"One-minute heart rate recovery and clinical outcomes in transthyretin cardiac amyloidosis: incremental model fit beyond conventional CPET indices","publication_year":2026,"publication_date":"2026-10-21","ids":{"openalex":"https://openalex.org/W7223248397","doi":"https://doi.org/10.1093/ehjopen/oeag181","pmid":"https://pubmed.ncbi.nlm.nih.gov/42979091","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/13728343"},"language":"en","primary_location":{"id":"doi:10.1093/ehjopen/oeag181","doi":"https://doi.org/10.1093/ehjopen/oeag181","is_oa":true,"landing_page_url":"https://doi.org/10.1093/ehjopen/oeag181","pdf_url":"https://academic.oup.com/ehjopen/advance-article-pdf/doi/10.1093/ehjopen/oeag181/72372780/oeag181.pdf","source":{"id":"https://openalex.org/S4210237792","display_name":"European Heart Journal Open","issn_l":"2752-4191","issn":["2752-4191"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","jufo-1","ki-jl-1","norway-1","vabb-shw"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"European Heart Journal Open","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://academic.oup.com/ehjopen/advance-article-pdf/doi/10.1093/ehjopen/oeag181/72372780/oeag181.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5135268781","display_name":"Antonio K\u00f6sters","orcid":"https://orcid.org/0009-0001-5837-5708","observed_orcids":["https://orcid.org/0009-0001-5837-5708"]},"institutions":[{"id":"https://openalex.org/I76134821","display_name":"Medical University of Vienna","ror":"https://ror.org/05n3x4p02","country_code":"AT","type":"education","lineage":["https://openalex.org/I76134821"]}],"countries":["AT"],"is_corresponding":false,"raw_author_name":"Antonio K\u00f6sters","raw_affiliation_strings":["Division of Cardiology, Department of Internal Medicine II, Medical University of Vienna , Spitalgasse 23, Vienna 1090 ,"],"raw_orcid":"https://orcid.org/0009-0001-5837-5708","affiliations":[{"raw_affiliation_string":"Division of Cardiology, Department of Internal Medicine II, Medical University of Vienna , Spitalgasse 23, Vienna 1090 ,","institution_ids":["https://openalex.org/I76134821"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5001021929","display_name":"Nikita Ermolaev","orcid":"https://orcid.org/0009-0007-2744-4233","observed_orcids":["https://orcid.org/0009-0007-2744-4233"]},"institutions":[{"id":"https://openalex.org/I76134821","display_name":"Medical University of Vienna","ror":"https://ror.org/05n3x4p02","country_code":"AT","type":"education","lineage":["https://openalex.org/I76134821"]}],"countries":["AT"],"is_corresponding":false,"raw_author_name":"Nikita Ermolaev","raw_affiliation_strings":["Division of Cardiology, Department of Internal Medicine II, Medical University of Vienna , Spitalgasse 23, Vienna 1090 ,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Cardiology, Department of Internal Medicine II, Medical University of Vienna , Spitalgasse 23, Vienna 1090 ,","institution_ids":["https://openalex.org/I76134821"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5061051583","display_name":"Mahshid Eslami","orcid":"https://orcid.org/0009-0003-7401-2135","observed_orcids":["https://orcid.org/0009-0003-7401-2135"]},"institutions":[{"id":"https://openalex.org/I76134821","display_name":"Medical University of Vienna","ror":"https://ror.org/05n3x4p02","country_code":"AT","type":"education","lineage":["https://openalex.org/I76134821"]}],"countries":["AT"],"is_corresponding":false,"raw_author_name":"Mahshid Eslami","raw_affiliation_strings":["Division of Cardiology, Department of Internal Medicine II, Medical University of Vienna , Spitalgasse 23, Vienna 1090 ,"],"raw_orcid":"https://orcid.org/0009-0003-7401-2135","affiliations":[{"raw_affiliation_string":"Division of Cardiology, Department of Internal Medicine II, Medical University of Vienna , Spitalgasse 23, Vienna 1090 ,","institution_ids":["https://openalex.org/I76134821"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5139538479","display_name":"Leonhard Lichtblau","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I76134821","display_name":"Medical University of Vienna","ror":"https://ror.org/05n3x4p02","country_code":"AT","type":"education","lineage":["https://openalex.org/I76134821"]}],"countries":["AT"],"is_corresponding":false,"raw_author_name":"Leonhard Lichtblau","raw_affiliation_strings":["Division of Cardiology, Department of Internal Medicine II, Medical University of Vienna , Spitalgasse 23, Vienna 1090 ,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Cardiology, Department of Internal Medicine II, Medical University of Vienna , Spitalgasse 23, Vienna 1090 ,","institution_ids":["https://openalex.org/I76134821"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5143493076","display_name":"Lisa Seilinger","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I76134821","display_name":"Medical University of Vienna","ror":"https://ror.org/05n3x4p02","country_code":"AT","type":"education","lineage":["https://openalex.org/I76134821"]}],"countries":["AT"],"is_corresponding":false,"raw_author_name":"Lisa Seilinger","raw_affiliation_strings":["Division of Cardiology, Department of Internal Medicine II, Medical University of Vienna , Spitalgasse 23, Vienna 1090 ,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Cardiology, Department of Internal Medicine II, Medical University of Vienna , Spitalgasse 23, Vienna 1090 ,","institution_ids":["https://openalex.org/I76134821"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5152659934","display_name":"Stefanie Pahr","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I76134821","display_name":"Medical University of Vienna","ror":"https://ror.org/05n3x4p02","country_code":"AT","type":"education","lineage":["https://openalex.org/I76134821"]}],"countries":["AT"],"is_corresponding":false,"raw_author_name":"Stefanie Pahr","raw_affiliation_strings":["Division of Cardiology, Department of Internal Medicine II, Medical University of Vienna , Spitalgasse 23, Vienna 1090 ,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Cardiology, Department of Internal Medicine II, Medical University of Vienna , Spitalgasse 23, Vienna 1090 ,","institution_ids":["https://openalex.org/I76134821"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5023417526","display_name":"Mariusz Tadeusz Grzeda","orcid":"https://orcid.org/0000-0003-2777-8763","observed_orcids":["https://orcid.org/0000-0003-2777-8763","https://orcid.org/0000-0002-4249-2520"]},"institutions":[{"id":"https://openalex.org/I36234482","display_name":"University of Bristol","ror":"https://ror.org/0524sp257","country_code":"GB","type":"education","lineage":["https://openalex.org/I36234482"]},{"id":"https://openalex.org/I4210116323","display_name":"Galen Research (United Kingdom)","ror":"https://ror.org/02e9za279","country_code":"GB","type":"company","lineage":["https://openalex.org/I4210116323"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Mariusz Grzeda","raw_affiliation_strings":["Department of Population Health Sciences, Bristol Medical School, University of Bristol, Oakfield House, Oakfield Grove, Bristol BS8 2BN ,","Galen Research Ltd , Koba, 100 Barbirolli Square, Manchester M2 3BD, United Kingdom"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Population Health Sciences, Bristol Medical School, University of Bristol, Oakfield House, Oakfield Grove, Bristol BS8 2BN ,","institution_ids":["https://openalex.org/I36234482"]},{"raw_affiliation_string":"Galen Research Ltd , Koba, 100 Barbirolli Square, Manchester M2 3BD, United Kingdom","institution_ids":["https://openalex.org/I4210116323"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5035929926","display_name":"Roza Badr Eslam","orcid":"https://orcid.org/0000-0002-0360-2360","observed_orcids":["https://orcid.org/0000-0002-0360-2360"]},"institutions":[{"id":"https://openalex.org/I76134821","display_name":"Medical University of Vienna","ror":"https://ror.org/05n3x4p02","country_code":"AT","type":"education","lineage":["https://openalex.org/I76134821"]}],"countries":["AT"],"is_corresponding":true,"raw_author_name":"Roza Badr Eslam","raw_affiliation_strings":["Department of Clinical Pharmacology, Medical University of Vienna , Spitalgasse 23, Vienna 1090 ,","Division of Cardiology, Department of Internal Medicine II, Medical University of Vienna , Spitalgasse 23, Vienna 1090 ,"],"raw_orcid":"https://orcid.org/0000-0002-0360-2360","affiliations":[{"raw_affiliation_string":"Department of Clinical Pharmacology, Medical University of Vienna , Spitalgasse 23, Vienna 1090 ,","institution_ids":["https://openalex.org/I76134821"]},{"raw_affiliation_string":"Division of Cardiology, Department of Internal Medicine II, Medical University of Vienna , Spitalgasse 23, Vienna 1090 ,","institution_ids":["https://openalex.org/I76134821"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5035929926"],"corresponding_institution_ids":["https://openalex.org/I76134821"],"apc_list":{"value":2365,"currency":"EUR","value_usd":2673},"apc_paid":{"value":2365,"currency":"EUR","value_usd":2673},"fwci":0.0,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":{"value":0.8236413,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"6","issue":"6","first_page":"oeag181","last_page":"oeag181"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11305","display_name":"Amyloidosis: Diagnosis, Treatment, Outcomes","score":0.9814000129699707,"subfield":{"id":"https://openalex.org/subfields/2724","display_name":"Internal Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11305","display_name":"Amyloidosis: Diagnosis, Treatment, Outcomes","score":0.9814000129699707,"subfield":{"id":"https://openalex.org/subfields/2724","display_name":"Internal Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11209","display_name":"Cardiovascular and exercise physiology","score":0.016899999231100082,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11922","display_name":"Cardiovascular Effects of Exercise","score":0.0003000000142492354,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/heart-rate-recovery","display_name":"heart rate recovery","score":0.8669999837875366},{"id":"https://openalex.org/keywords/transthyretin-amyloid-cardiomyopathy","display_name":"transthyretin amyloid cardiomyopathy","score":0.9879999756813049},{"id":"https://openalex.org/keywords/cardiopulmonary-exercise-testing","display_name":"cardiopulmonary exercise testing","score":0.9729999899864197},{"id":"https://openalex.org/keywords/all-cause-mortality","display_name":"all-cause mortality","score":0.8019999861717224},{"id":"https://openalex.org/keywords/heart-failure-hospitalization","display_name":"heart failure hospitalization","score":0.9879999756813049},{"id":"https://openalex.org/keywords/peak-oxygen-uptake","display_name":"peak oxygen uptake","score":0.5920000076293945},{"id":"https://openalex.org/keywords/ventilatory-efficiency","display_name":"ventilatory efficiency","score":0.8759999871253967},{"id":"https://openalex.org/keywords/nt-probnp","display_name":"NT-proBNP","score":0.8399999737739563},{"id":"https://openalex.org/keywords/prognosis","display_name":"prognosis","score":0.4819999933242798},{"id":"https://openalex.org/keywords/model-discrimination","display_name":"model discrimination","score":0.6029999852180481}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.7366999983787537},{"id":"https://openalex.org/C164705383","wikidata":"https://www.wikidata.org/wiki/Q10379","display_name":"Cardiology","level":1,"score":0.7322999835014343},{"id":"https://openalex.org/C121157162","wikidata":"https://www.wikidata.org/wiki/Q419999","display_name":"Transthyretin","level":2,"score":0.7059999704360962},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.7009999752044678},{"id":"https://openalex.org/C44249647","wikidata":"https://www.wikidata.org/wiki/Q208498","display_name":"Confidence interval","level":2,"score":0.5246999859809875},{"id":"https://openalex.org/C2777953023","wikidata":"https://www.wikidata.org/wiki/Q1073121","display_name":"Heart rate","level":3,"score":0.46209999918937683},{"id":"https://openalex.org/C23131810","wikidata":"https://www.wikidata.org/wiki/Q818574","display_name":"Observational study","level":2,"score":0.44749999046325684},{"id":"https://openalex.org/C50382708","wikidata":"https://www.wikidata.org/wiki/Q223218","display_name":"Proportional hazards model","level":2,"score":0.42309999465942383},{"id":"https://openalex.org/C179755657","wikidata":"https://www.wikidata.org/wiki/Q58702","display_name":"Mortality rate","level":2,"score":0.38960000872612},{"id":"https://openalex.org/C2778856057","wikidata":"https://www.wikidata.org/wiki/Q6015458","display_name":"Incremental exercise","level":4,"score":0.3828999996185303},{"id":"https://openalex.org/C2778198053","wikidata":"https://www.wikidata.org/wiki/Q181754","display_name":"Heart failure","level":2,"score":0.36730000376701355},{"id":"https://openalex.org/C2781197716","wikidata":"https://www.wikidata.org/wiki/Q864574","display_name":"Biomarker","level":2,"score":0.3328000009059906},{"id":"https://openalex.org/C12713177","wikidata":"https://www.wikidata.org/wiki/Q1900281","display_name":"Perspective (graphical)","level":2,"score":0.3310999870300293},{"id":"https://openalex.org/C207103383","wikidata":"https://www.wikidata.org/wiki/Q3930246","display_name":"Hazard ratio","level":3,"score":0.3239000141620636},{"id":"https://openalex.org/C2779161974","wikidata":"https://www.wikidata.org/wiki/Q815819","display_name":"Atrial fibrillation","level":2,"score":0.31520000100135803},{"id":"https://openalex.org/C2778067643","wikidata":"https://www.wikidata.org/wiki/Q166507","display_name":"Interval (graph theory)","level":2,"score":0.3118000030517578},{"id":"https://openalex.org/C2779951007","wikidata":"https://www.wikidata.org/wiki/Q816798","display_name":"Amyloidosis","level":2,"score":0.3098999857902527},{"id":"https://openalex.org/C2776291640","wikidata":"https://www.wikidata.org/wiki/Q2912517","display_name":"Value (mathematics)","level":2,"score":0.30250000953674316},{"id":"https://openalex.org/C2780040984","wikidata":"https://www.wikidata.org/wiki/Q79785","display_name":"Electrocardiography","level":2,"score":0.29010000824928284},{"id":"https://openalex.org/C2777720157","wikidata":"https://www.wikidata.org/wiki/Q7306947","display_name":"Reentry","level":2,"score":0.28850001096725464},{"id":"https://openalex.org/C3019211846","wikidata":"https://www.wikidata.org/wiki/Q492905","display_name":"Ventricular filling","level":4,"score":0.28439998626708984},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.2757999897003174},{"id":"https://openalex.org/C2777984932","wikidata":"https://www.wikidata.org/wiki/Q7336293","display_name":"Risk of mortality","level":2,"score":0.25279998779296875},{"id":"https://openalex.org/C10515644","wikidata":"https://www.wikidata.org/wiki/Q543310","display_name":"Survival analysis","level":2,"score":0.2506999969482422}],"mesh":[],"locations_count":4,"locations":[{"id":"doi:10.1093/ehjopen/oeag181","doi":"https://doi.org/10.1093/ehjopen/oeag181","is_oa":true,"landing_page_url":"https://doi.org/10.1093/ehjopen/oeag181","pdf_url":"https://academic.oup.com/ehjopen/advance-article-pdf/doi/10.1093/ehjopen/oeag181/72372780/oeag181.pdf","source":{"id":"https://openalex.org/S4210237792","display_name":"European Heart Journal Open","issn_l":"2752-4191","issn":["2752-4191"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","jufo-1","ki-jl-1","norway-1","vabb-shw"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"European Heart Journal Open","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:13728343","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC13728343/","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC13728343/pdf/oeag181.pdf","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Eur Heart J Open","raw_type":"Text"},{"id":"pmid:42979091","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/42979091","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"European heart journal open","raw_type":"Journal Article"},{"id":"pmh:oai:research-information.bris.ac.uk:openaire/9f489bd7-b982-4236-ba49-eb9876ee9218","doi":null,"is_oa":true,"landing_page_url":"https://research-information.bris.ac.uk/en/publications/9f489bd7-b982-4236-ba49-eb9876ee9218","pdf_url":null,"source":{"id":"https://openalex.org/S7407055359","display_name":"Explore Bristol Research","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"K\u00f6sters, A, Ermolaev, N, Eslami, M, Lichtblau, L, Seilinger, L, Pahr, S, Grzeda, M & Badr Eslam, R 2026, 'One-Minute Heart Rate Recovery and Clinical Outcomes in Transthyretin Cardiac Amyloidosis : Incremental Model Fit Beyond Conventional CPET Indices', European Heart Journal Open. https://doi.org/10.1093/ehjopen/oeag181","raw_type":"info:eu-repo/semantics/article"}],"best_oa_location":{"id":"doi:10.1093/ehjopen/oeag181","doi":"https://doi.org/10.1093/ehjopen/oeag181","is_oa":true,"landing_page_url":"https://doi.org/10.1093/ehjopen/oeag181","pdf_url":"https://academic.oup.com/ehjopen/advance-article-pdf/doi/10.1093/ehjopen/oeag181/72372780/oeag181.pdf","source":{"id":"https://openalex.org/S4210237792","display_name":"European Heart Journal Open","issn_l":"2752-4191","issn":["2752-4191"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","jufo-1","ki-jl-1","norway-1","vabb-shw"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"European Heart Journal Open","raw_type":"journal-article"},"sustainable_development_goals":[{"score":1.0,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[],"funders":[{"id":"https://openalex.org/F4320307770","display_name":"AstraZeneca","ror":"https://ror.org/04r9x1a08"},{"id":"https://openalex.org/F4320307771","display_name":"Bayer","ror":"https://ror.org/04hmn8g73"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W7223248397.pdf","grobid_xml":"https://content.openalex.org/works/W7223248397.grobid-xml"},"referenced_works_count":28,"referenced_works":["https://openalex.org/W1988582346","https://openalex.org/W2033925409","https://openalex.org/W2089895947","https://openalex.org/W2096857234","https://openalex.org/W2318588083","https://openalex.org/W2337532627","https://openalex.org/W2346989408","https://openalex.org/W2613107176","https://openalex.org/W2795990770","https://openalex.org/W2885222854","https://openalex.org/W2888036721","https://openalex.org/W2937755845","https://openalex.org/W3085675504","https://openalex.org/W3091354871","https://openalex.org/W3114105654","https://openalex.org/W3145296972","https://openalex.org/W3186668188","https://openalex.org/W4206353703","https://openalex.org/W4283717325","https://openalex.org/W4313892290","https://openalex.org/W4392509018","https://openalex.org/W4398144067","https://openalex.org/W4399982975","https://openalex.org/W4400682254","https://openalex.org/W4404425956","https://openalex.org/W4409106176","https://openalex.org/W4409869722","https://openalex.org/W4409997085"],"related_works":["https://openalex.org/W2937755845","https://openalex.org/W4406412609","https://openalex.org/W4309368425","https://openalex.org/W7167246917","https://openalex.org/W4387252526","https://openalex.org/W3215844062","https://openalex.org/W7106693685","https://openalex.org/W3216028215","https://openalex.org/W3085675504","https://openalex.org/W7132815129"],"abstract_inverted_index":{"Abstract":[0],"Aims":[1],"To":[2],"assess":[3],"the":[4,85,181,221],"association":[5],"of":[6,87,166],"1-min":[7],"heart":[8,68,71],"rate":[9,69,72],"recovery":[10,59],"(HRR1)":[11],"with":[12,40,119,137,145,163,239],"clinical":[13],"outcomes":[14,240],"and":[15,25,36,84,101,105,125,180,201,215,244],"its":[16],"incremental":[17],"contribution":[18],"to":[19,211,218],"model":[20,195,246],"fit":[21,196],"beyond":[22,253],"peak":[23,67,99],"VO2":[24,100],"ventilatory":[26],"efficiency":[27],"(VE/VCO2":[28],"slope)":[29],"in":[30,51,130],"transthyretin":[31],"cardiac":[32],"amyloidosis":[33],"(ATTR-CM).":[34],"Methods":[35],"results":[37],"Consecutive":[38],"adults":[39],"confirmed":[41],"ATTR-CM":[42],"undergoing":[43],"symptom-limited":[44],"cardiopulmonary":[45],"exercise":[46],"testing":[47],"(CPET)":[48],"were":[49,111,123,225,250],"included":[50,134,142],"this":[52],"single-centre":[53],"observational":[54],"study.":[55],"During":[56],"standardized":[57],"active":[58],"at":[60],"24":[61],"W,":[62],"HRR1":[63,127,149,160,193,236],"was":[64,128,150,161,256],"defined":[65],"as":[66],"minus":[70],"exactly":[73],"60":[74],"s":[75],"after":[76,227,241],"exercise.":[77],"Cox":[78],"proportional-hazards":[79],"models":[80,94],"evaluated":[81],"all-cause":[82],"mortality":[83,88,167,214],"composite":[86,182,222],"or":[89,232],"first":[90],"heart-failure":[91],"hospitalization.":[92],"Principal":[93],"adjusted":[95],"for":[96,213,220,230],"age,":[97],"sex,":[98],"VE/VCO2":[102],"slope;":[103],"NT-proBNP":[104,231],"National":[106],"Amyloidosis":[107],"Centre":[108],"(NAC)":[109],"stage":[110],"examined":[112],"separately.":[113],"Of":[114],"161":[115],"baseline":[116],"patients,":[117],"11":[118],"unverifiable":[120],"heart-rate":[121],"measurements":[122],"excluded,":[124],"exact":[126],"available":[129],"110.":[131],"Mortality":[132],"analysis":[133,141],"105":[135],"patients":[136,144],"33":[138],"deaths;":[139],"composite-outcome":[140],"107":[143],"51":[146],"events.":[147],"Median":[148],"15.5":[151],"bpm.":[152],"In":[153],"conventional":[154],"CPET-adjusted":[155],"models,":[156],"each":[157],"10-bpm":[158],"greater":[159],"associated":[162,238],"lower":[164],"hazards":[165],"[hazard":[168],"ratio":[169],"(HR)":[170],"0.65,":[171],"95%":[172,186],"confidence":[173],"interval":[174],"(CI)":[175],"0.44\u20130.95;":[176],"P":[177,189,198,202],"=":[178,190,199,203],"0.028]":[179],"outcome":[183],"(HR":[184],"0.74,":[185],"CI":[187],"0.57\u20130.97;":[188],"0.029).":[191],"Adding":[192],"improved":[194,245],"(likelihood-ratio":[197],"0.017":[200],"0.021,":[204],"respectively);":[205],"apparent":[206],"C-indices":[207],"increased":[208],"from":[209,216],"0.770":[210],"0.795":[212],"0.695":[217],"0.699":[219],"outcome.":[223],"Associations":[224],"non-significant":[226],"separate":[228],"adjustment":[229,243],"NAC":[233],"stage.":[234],"Conclusion":[235],"remained":[237],"CPET":[242],"fit.":[247],"Discrimination":[248],"gains":[249],"modest;":[251],"value":[252],"biomarker":[254],"staging":[255],"unproven.":[257]},"counts_by_year":[],"updated_date":"2026-11-08T12:12:28.789561","created_date":"2026-10-23T00:00:00"}