{"id":"https://openalex.org/W7223187178","doi":"https://doi.org/10.1080/21505594.2026.2749928","title":"D-enantiomeric \u03b2-casein 197 disrupts biofilm-associated infection of MDR Pseudomonas aeruginosa and Acinetobacter baumannii through superior LPS binding and host cell protection","display_name":"D-enantiomeric \u03b2-casein 197 disrupts biofilm-associated infection of MDR Pseudomonas aeruginosa and Acinetobacter baumannii through superior LPS binding and host cell protection","publication_year":2026,"publication_date":"2026-10-22","ids":{"openalex":"https://openalex.org/W7223187178","doi":"https://doi.org/10.1080/21505594.2026.2749928","pmid":"https://pubmed.ncbi.nlm.nih.gov/42908345","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/13711990"},"language":"en","primary_location":{"id":"doi:10.1080/21505594.2026.2749928","doi":"https://doi.org/10.1080/21505594.2026.2749928","is_oa":true,"landing_page_url":"https://doi.org/10.1080/21505594.2026.2749928","pdf_url":"https://www.tandfonline.com/doi/pdf/10.1080/21505594.2026.2749928?needAccess=true","source":{"id":"https://openalex.org/S2484688887","display_name":"Virulence","issn_l":"2150-5594","issn":["2150-5594","2150-5608"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320547","host_organization_name":"Taylor & Francis","host_organization_lineage":["https://openalex.org/P4310320547","https://openalex.org/P4310320449"],"host_organization_lineage_names":["Taylor & Francis","Informa"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Virulence","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","datacite","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://www.tandfonline.com/doi/pdf/10.1080/21505594.2026.2749928?needAccess=true","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5068143863","display_name":"Kaichong Jiang","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I87445476","display_name":"Xi'an Jiaotong University","ror":"https://ror.org/017zhmm22","country_code":"CN","type":"education","lineage":["https://openalex.org/I87445476"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Kaichong Jiang","raw_affiliation_strings":["Affiliated Children\u2019s Hospital of Xi\u2019an Jiaotong University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Affiliated Children\u2019s Hospital of Xi\u2019an Jiaotong University","institution_ids":["https://openalex.org/I87445476"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5159245147","display_name":"Wei Wang","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I87445476","display_name":"Xi'an Jiaotong University","ror":"https://ror.org/017zhmm22","country_code":"CN","type":"education","lineage":["https://openalex.org/I87445476"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Wei Wang","raw_affiliation_strings":["Affiliated Children\u2019s Hospital of Xi\u2019an Jiaotong University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Affiliated Children\u2019s Hospital of Xi\u2019an Jiaotong University","institution_ids":["https://openalex.org/I87445476"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100296230","display_name":"Hong Lei","orcid":"https://orcid.org/0000-0001-6518-6190","observed_orcids":["https://orcid.org/0000-0001-6518-6190","https://orcid.org/0009-0007-3734-4578"]},"institutions":[{"id":"https://openalex.org/I87445476","display_name":"Xi'an Jiaotong University","ror":"https://ror.org/017zhmm22","country_code":"CN","type":"education","lineage":["https://openalex.org/I87445476"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Hong Lei","raw_affiliation_strings":["Affiliated Children\u2019s Hospital of Xi\u2019an Jiaotong University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Affiliated Children\u2019s Hospital of Xi\u2019an Jiaotong University","institution_ids":["https://openalex.org/I87445476"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100610980","display_name":"Tianhao Wang","orcid":"https://orcid.org/0000-0001-8334-2476","observed_orcids":["https://orcid.org/0000-0001-8334-2476"]},"institutions":[{"id":"https://openalex.org/I87445476","display_name":"Xi'an Jiaotong University","ror":"https://ror.org/017zhmm22","country_code":"CN","type":"education","lineage":["https://openalex.org/I87445476"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Tianhao Wang","raw_affiliation_strings":["Affiliated Children\u2019s Hospital of Xi\u2019an Jiaotong University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Affiliated Children\u2019s Hospital of Xi\u2019an Jiaotong University","institution_ids":["https://openalex.org/I87445476"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5159252975","display_name":"Lei Xu","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210144214","display_name":"Jiangsu University of Technology","ror":"https://ror.org/04jabhf80","country_code":"CN","type":"education","lineage":["https://openalex.org/I4210144214"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Lei Xu","raw_affiliation_strings":["Jiangsu University of Technology"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Jiangsu University of Technology","institution_ids":["https://openalex.org/I4210144214"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5135893038","display_name":"Ying Yang","orcid":"https://orcid.org/0009-0007-1236-1873","observed_orcids":["https://orcid.org/0009-0007-1236-1873"]},"institutions":[{"id":"https://openalex.org/I87445476","display_name":"Xi'an Jiaotong University","ror":"https://ror.org/017zhmm22","country_code":"CN","type":"education","lineage":["https://openalex.org/I87445476"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Ying Yang","raw_affiliation_strings":["Affiliated Children\u2019s Hospital of Xi\u2019an Jiaotong University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Affiliated Children\u2019s Hospital of Xi\u2019an Jiaotong University","institution_ids":["https://openalex.org/I87445476"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5021897788","display_name":"Rui Zhou","orcid":"https://orcid.org/0000-0002-7903-9965","observed_orcids":["https://orcid.org/0000-0002-7903-9965"]},"institutions":[{"id":"https://openalex.org/I87445476","display_name":"Xi'an Jiaotong University","ror":"https://ror.org/017zhmm22","country_code":"CN","type":"education","lineage":["https://openalex.org/I87445476"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Rui Zhou","raw_affiliation_strings":["Affiliated Children\u2019s Hospital of Xi\u2019an Jiaotong University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Affiliated Children\u2019s Hospital of Xi\u2019an Jiaotong University","institution_ids":["https://openalex.org/I87445476"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5159248595","display_name":"Tianwei Lin","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I87445476","display_name":"Xi'an Jiaotong University","ror":"https://ror.org/017zhmm22","country_code":"CN","type":"education","lineage":["https://openalex.org/I87445476"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Tianwei Lin","raw_affiliation_strings":["Affiliated Children\u2019s Hospital of Xi\u2019an Jiaotong University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Affiliated Children\u2019s Hospital of Xi\u2019an Jiaotong University","institution_ids":["https://openalex.org/I87445476"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5157833227","display_name":"Yinong Huang","orcid":"https://orcid.org/0009-0003-1728-6594","observed_orcids":["https://orcid.org/0009-0003-1728-6594"]},"institutions":[{"id":"https://openalex.org/I87445476","display_name":"Xi'an Jiaotong University","ror":"https://ror.org/017zhmm22","country_code":"CN","type":"education","lineage":["https://openalex.org/I87445476"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Yinong Huang","raw_affiliation_strings":["Affiliated Children\u2019s Hospital of Xi\u2019an Jiaotong University"],"raw_orcid":"https://orcid.org/0009-0003-1728-6594","affiliations":[{"raw_affiliation_string":"Affiliated Children\u2019s Hospital of Xi\u2019an Jiaotong University","institution_ids":["https://openalex.org/I87445476"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5157833227"],"corresponding_institution_ids":["https://openalex.org/I87445476"],"apc_list":{"value":2085,"currency":"GBP","value_usd":2557},"apc_paid":{"value":2085,"currency":"GBP","value_usd":2557},"fwci":0.0,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":{"value":0.78194055,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"17","issue":"1","first_page":"2749928","last_page":"2749928"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11103","display_name":"Antimicrobial Peptides and Activities","score":0.9854000210762024,"subfield":{"id":"https://openalex.org/subfields/2404","display_name":"Microbiology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11103","display_name":"Antimicrobial Peptides and Activities","score":0.9854000210762024,"subfield":{"id":"https://openalex.org/subfields/2404","display_name":"Microbiology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10593","display_name":"Bacterial biofilms and quorum sensing","score":0.010999999940395355,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12526","display_name":"Antimicrobial agents and applications","score":0.0008999999845400453,"subfield":{"id":"https://openalex.org/subfields/2402","display_name":"Applied Microbiology and Biotechnology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/antimicrobial-peptides","display_name":"antimicrobial peptides","score":0.8709999918937683},{"id":"https://openalex.org/keywords/antibiofilm-activity","display_name":"antibiofilm activity","score":0.8579999804496765},{"id":"https://openalex.org/keywords/multidrug-resistant-pseudomonas-aeruginosa","display_name":"multidrug-resistant Pseudomonas aeruginosa","score":0.953000009059906},{"id":"https://openalex.org/keywords/acinetobacter-baumannii","display_name":"Acinetobacter baumannii","score":0.9750000238418579},{"id":"https://openalex.org/keywords/lps-binding","display_name":"LPS binding","score":0.7369999885559082},{"id":"https://openalex.org/keywords/lipid-a","display_name":"lipid A","score":0.875},{"id":"https://openalex.org/keywords/membrane-damage","display_name":"membrane damage","score":0.6679999828338623},{"id":"https://openalex.org/keywords/bacterial-motility-inhibition","display_name":"bacterial motility inhibition","score":0.8970000147819519},{"id":"https://openalex.org/keywords/macrophage-mediated-cytotoxicity","display_name":"macrophage cytotoxicity","score":0.8640000224113464},{"id":"https://openalex.org/keywords/galleria-mellonella-infection-model","display_name":"Galleria mellonella infection model","score":0.8740000128746033},{"id":"https://openalex.org/keywords/nosocomial-infections","display_name":"nosocomial infections","score":0.7670000195503235},{"id":"https://openalex.org/keywords/host-cell-protection","display_name":"host cell protection","score":0.5799999833106995}],"concepts":[{"id":"https://openalex.org/C2776315533","wikidata":"https://www.wikidata.org/wiki/Q3241189","display_name":"Acinetobacter baumannii","level":4,"score":0.8414000272750854},{"id":"https://openalex.org/C89423630","wikidata":"https://www.wikidata.org/wiki/Q7193","display_name":"Microbiology","level":1,"score":0.7705000042915344},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.7682999968528748},{"id":"https://openalex.org/C2777637488","wikidata":"https://www.wikidata.org/wiki/Q31856","display_name":"Pseudomonas aeruginosa","level":3,"score":0.7631999850273132},{"id":"https://openalex.org/C126831891","wikidata":"https://www.wikidata.org/wiki/Q221673","display_name":"Host (biology)","level":2,"score":0.4787999987602234},{"id":"https://openalex.org/C523546767","wikidata":"https://www.wikidata.org/wiki/Q10876","display_name":"Bacteria","level":2,"score":0.4657000005245209},{"id":"https://openalex.org/C133936738","wikidata":"https://www.wikidata.org/wiki/Q643839","display_name":"Multiple drug resistance","level":3,"score":0.38580000400543213},{"id":"https://openalex.org/C159047783","wikidata":"https://www.wikidata.org/wiki/Q7215","display_name":"Virology","level":1,"score":0.3637000024318695},{"id":"https://openalex.org/C2781433018","wikidata":"https://www.wikidata.org/wiki/Q133966","display_name":"Pseudomonadales","level":4,"score":0.3443000018596649},{"id":"https://openalex.org/C60987743","wikidata":"https://www.wikidata.org/wiki/Q1460232","display_name":"Virulence","level":3,"score":0.329800009727478},{"id":"https://openalex.org/C501593827","wikidata":"https://www.wikidata.org/wiki/Q12187","display_name":"Antibiotics","level":2,"score":0.32829999923706055},{"id":"https://openalex.org/C2776738503","wikidata":"https://www.wikidata.org/wiki/Q138058","display_name":"Pseudomonadaceae","level":4,"score":0.32030001282691956},{"id":"https://openalex.org/C2778523567","wikidata":"https://www.wikidata.org/wiki/Q310457","display_name":"Acinetobacter","level":3,"score":0.3124000132083893},{"id":"https://openalex.org/C136449434","wikidata":"https://www.wikidata.org/wiki/Q428253","display_name":"Innate immune system","level":3,"score":0.2921999990940094},{"id":"https://openalex.org/C180223184","wikidata":"https://www.wikidata.org/wiki/Q4839986","display_name":"Bacterial genetics","level":4,"score":0.27140000462532043},{"id":"https://openalex.org/C2776983828","wikidata":"https://www.wikidata.org/wiki/Q1974989","display_name":"Neisseriaceae","level":3,"score":0.2646999955177307},{"id":"https://openalex.org/C4937899","wikidata":"https://www.wikidata.org/wiki/Q68541106","display_name":"Antimicrobial","level":2,"score":0.26429998874664307},{"id":"https://openalex.org/C2776460866","wikidata":"https://www.wikidata.org/wiki/Q170065","display_name":"Pathogen","level":2,"score":0.2605000138282776},{"id":"https://openalex.org/C94665300","wikidata":"https://www.wikidata.org/wiki/Q63391344","display_name":"Antibiotic resistance","level":3,"score":0.25769999623298645},{"id":"https://openalex.org/C8891405","wikidata":"https://www.wikidata.org/wiki/Q1059","display_name":"Immune system","level":2,"score":0.25690001249313354},{"id":"https://openalex.org/C2779259085","wikidata":"https://www.wikidata.org/wiki/Q418946","display_name":"Colistin","level":3,"score":0.25360000133514404},{"id":"https://openalex.org/C114851261","wikidata":"https://www.wikidata.org/wiki/Q12147416","display_name":"Drug resistance","level":2,"score":0.2531999945640564}],"mesh":[{"descriptor_ui":"D000089882","descriptor_name":"Antimicrobial Peptides","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D000151","descriptor_name":"Acinetobacter Infections","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":false},{"descriptor_ui":"D000151","descriptor_name":"Acinetobacter Infections","qualifier_ui":"Q000382","qualifier_name":"microbiology","is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000900","descriptor_name":"Anti-Bacterial Agents","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D000900","descriptor_name":"Anti-Bacterial Agents","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D002364","descriptor_name":"Caseins","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D002364","descriptor_name":"Caseins","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008070","descriptor_name":"Lipopolysaccharides","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D009036","descriptor_name":"Moths","qualifier_ui":"Q000382","qualifier_name":"microbiology","is_major_topic":false},{"descriptor_ui":"D011550","descriptor_name":"Pseudomonas aeruginosa","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D011550","descriptor_name":"Pseudomonas aeruginosa","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D011552","descriptor_name":"Pseudomonas Infections","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":false},{"descriptor_ui":"D011552","descriptor_name":"Pseudomonas Infections","qualifier_ui":"Q000382","qualifier_name":"microbiology","is_major_topic":false},{"descriptor_ui":"D018441","descriptor_name":"Biofilms","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D024901","descriptor_name":"Drug Resistance, Multiple, Bacterial","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D040981","descriptor_name":"Acinetobacter baumannii","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D040981","descriptor_name":"Acinetobacter baumannii","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D062105","descriptor_name":"Molecular Docking Simulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":6,"locations":[{"id":"doi:10.1080/21505594.2026.2749928","doi":"https://doi.org/10.1080/21505594.2026.2749928","is_oa":true,"landing_page_url":"https://doi.org/10.1080/21505594.2026.2749928","pdf_url":"https://www.tandfonline.com/doi/pdf/10.1080/21505594.2026.2749928?needAccess=true","source":{"id":"https://openalex.org/S2484688887","display_name":"Virulence","issn_l":"2150-5594","issn":["2150-5594","2150-5608"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320547","host_organization_name":"Taylor & Francis","host_organization_lineage":["https://openalex.org/P4310320547","https://openalex.org/P4310320449"],"host_organization_lineage_names":["Taylor & Francis","Informa"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Virulence","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:13711990","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC13711990/","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC13711990/pdf/KVIR_17_2749928.pdf","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Virulence","raw_type":"Text"},{"id":"pmid:42908345","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/42908345","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Virulence","raw_type":"Journal Article"},{"id":"pmh:oai:doaj.org/article:56b98328d4364a1e8c90e3f1aed4c4ee","doi":null,"is_oa":false,"landing_page_url":"https://doaj.org/article/56b98328d4364a1e8c90e3f1aed4c4ee","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Virulence, Vol 17, Iss 1 (2026)","raw_type":"article"},{"id":"doi:10.6084/m9.figshare.34744649","doi":"https://doi.org/10.6084/m9.figshare.34744649","is_oa":true,"landing_page_url":"https://doi.org/10.6084/m9.figshare.34744649","pdf_url":null,"source":{"id":"https://openalex.org/S4377196282","display_name":"Figshare","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4210132348","host_organization_name":"Figshare (United Kingdom)","host_organization_lineage":["https://openalex.org/I4210132348"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"JournalArticle"},{"id":"doi:10.6084/m9.figshare.34744649.v1","doi":"https://doi.org/10.6084/m9.figshare.34744649.v1","is_oa":true,"landing_page_url":"https://doi.org/10.6084/m9.figshare.34744649.v1","pdf_url":null,"source":{"id":"https://openalex.org/S4377196282","display_name":"Figshare","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4210132348","host_organization_name":"Figshare (United Kingdom)","host_organization_lineage":["https://openalex.org/I4210132348"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"JournalArticle"}],"best_oa_location":{"id":"doi:10.1080/21505594.2026.2749928","doi":"https://doi.org/10.1080/21505594.2026.2749928","is_oa":true,"landing_page_url":"https://doi.org/10.1080/21505594.2026.2749928","pdf_url":"https://www.tandfonline.com/doi/pdf/10.1080/21505594.2026.2749928?needAccess=true","source":{"id":"https://openalex.org/S2484688887","display_name":"Virulence","issn_l":"2150-5594","issn":["2150-5594","2150-5608"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320547","host_organization_name":"Taylor & Francis","host_organization_lineage":["https://openalex.org/P4310320547","https://openalex.org/P4310320449"],"host_organization_lineage_names":["Taylor & Francis","Informa"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Virulence","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.9391000270843506,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G5999262464","display_name":null,"funder_award_id":"2025JC-YBQN-1203","funder_id":"https://openalex.org/F4320324173","funder_display_name":"Natural Science Foundation of Shaanxi Province"},{"id":"https://openalex.org/G7149803078","display_name":null,"funder_award_id":"xzy012022129","funder_id":"https://openalex.org/F4320335787","funder_display_name":"Fundamental Research Funds for the Central Universities"}],"funders":[{"id":"https://openalex.org/F4320324173","display_name":"Natural Science Foundation of Shaanxi Province","ror":null},{"id":"https://openalex.org/F4320335787","display_name":"Fundamental Research Funds for the Central Universities","ror":null}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W7223187178.pdf","grobid_xml":"https://content.openalex.org/works/W7223187178.grobid-xml"},"referenced_works_count":56,"referenced_works":["https://openalex.org/W1833417126","https://openalex.org/W1927301544","https://openalex.org/W1940255949","https://openalex.org/W1989942811","https://openalex.org/W2017914970","https://openalex.org/W2058916766","https://openalex.org/W2095721618","https://openalex.org/W2095894402","https://openalex.org/W2117834417","https://openalex.org/W2143215494","https://openalex.org/W2146837416","https://openalex.org/W2148070193","https://openalex.org/W2151921983","https://openalex.org/W2152683133","https://openalex.org/W2158594038","https://openalex.org/W2159435953","https://openalex.org/W2214330682","https://openalex.org/W2337903860","https://openalex.org/W2418269076","https://openalex.org/W2559271087","https://openalex.org/W2622044682","https://openalex.org/W2623129532","https://openalex.org/W2626490880","https://openalex.org/W2738070685","https://openalex.org/W2754882069","https://openalex.org/W2776579174","https://openalex.org/W2778732581","https://openalex.org/W2793220261","https://openalex.org/W2894483060","https://openalex.org/W2900331994","https://openalex.org/W2909796347","https://openalex.org/W2947136203","https://openalex.org/W2955344024","https://openalex.org/W3014350499","https://openalex.org/W3101923829","https://openalex.org/W3129095230","https://openalex.org/W3134998265","https://openalex.org/W3175863350","https://openalex.org/W3204048502","https://openalex.org/W3211299661","https://openalex.org/W4200393513","https://openalex.org/W4220675688","https://openalex.org/W4220766160","https://openalex.org/W4224276811","https://openalex.org/W4234317413","https://openalex.org/W4247333866","https://openalex.org/W4307156210","https://openalex.org/W4312138773","https://openalex.org/W4396721167","https://openalex.org/W4401044736","https://openalex.org/W4404540111","https://openalex.org/W4406178102","https://openalex.org/W4408339448","https://openalex.org/W4412428571","https://openalex.org/W7123579634","https://openalex.org/W7139939690"],"related_works":["https://openalex.org/W2158594038","https://openalex.org/W2140049316","https://openalex.org/W2678288201","https://openalex.org/W3172875306","https://openalex.org/W4376641212","https://openalex.org/W2738070685","https://openalex.org/W3046721888","https://openalex.org/W4386870159","https://openalex.org/W2995638615","https://openalex.org/W2015021843"],"abstract_inverted_index":{"Biofilms":[0],"formed":[1],"by":[2,28,69,76,96],"multidrug-resistant":[3],"(MDR)":[4],"Pseudomonas":[5],"aeruginosa":[6,60,181],"and":[7,18,42,48,61,75,99,121,151,157,184,197,230],"Acinetobacter":[8],"baumannii":[9,186],"are":[10,25],"a":[11,45,169,219],"major":[12],"cause":[13],"of":[14,58],"chronic":[15],"nosocomial":[16],"infections":[17],"therapeutic":[19],"failure.":[20],"L-form":[21,196],"antimicrobial":[22,236],"peptides":[23,32,140],"(AMPs)":[24],"rapidly":[26],"degraded":[27],"proteases,":[29],"whereas":[30],"D-enantiomeric":[31],"offer":[33],"enhanced":[34,228],"resistance":[35],"to":[36,71,78,194,206,244],"proteases.":[37],"Here,":[38],"we":[39],"synthesized":[40],"L-":[41],"D-\u03b2-casein":[43,174,216],"197,":[44],"milk-derived":[46],"AMP,":[47],"systematically":[49],"compared":[50,193],"their":[51],"antibiofilm":[52,221],"activities":[53],"against":[54,179,223],"eight":[55],"clinical":[56],"isolates":[57],"P.":[59,180],"A.":[62,130,185],"baumannii.":[63],"The":[64,131],"D-form":[65,88,109,132,153],"reduced":[66,154],"biofilm":[67],"biomass":[68],"up":[70,77],"83%":[72],"during":[73],"formation":[74],"88%":[79],"in":[80,160,241],"preformed":[81],"biofilms.":[82],"Mechanistic":[83],"analyses":[84],"revealed":[85],"that":[86,107,234],"the":[87,108,152,166,195],"caused":[89],"more":[90,134,163],"extensive":[91],"membrane":[92],"disruption,":[93],"as":[94,218],"demonstrated":[95],"flow":[97],"cytometry":[98],"transmission":[100],"electron":[101],"microscopy.":[102],"Isothermal":[103],"titration":[104],"calorimetry":[105],"showed":[106],"bound":[110],"LPS":[111,247],"with":[112,128,227],"higher":[113],"affinity":[114],"(KD":[115],"0.8":[116],"\u03bcM":[117],"vs":[118],"3.1":[119],"\u03bcM),":[120,150],"molecular":[122],"docking":[123],"identified":[124],"additional":[125],"hydrogen":[126],"bonds":[127],"lipid":[129],"also":[133],"effectively":[135,164],"inhibited":[136],"bacterial":[137,158],"motility.":[138],"Both":[139],"exhibited":[141],"low":[142],"cytotoxicity":[143,156],"toward":[144],"cells":[145],"(>90%":[146],"viability":[147],"at":[148,239],"100":[149],"bacteria-induced":[155],"internalization":[159],"infected":[161,199],"macrophages":[162],"than":[165],"L-form.":[167],"In":[168],"Galleria":[170],"mellonella":[171],"infection":[172],"model,":[173],"197":[175,217],"significantly":[176],"improved":[177],"survival":[178,203],"no.":[182,187],"R1":[183],"13":[188],"challenge":[189],"over":[190],"96":[191],"h":[192],"untreated":[198],"controls,":[200,208],"while":[201],"larval":[202],"remained":[204],"comparable":[205],"PBS":[207],"indicating":[209],"negligible":[210],"host":[211],"toxicity.":[212],"These":[213],"findings":[214],"identify":[215],"potent":[220],"peptide":[222],"MDR":[224],"Gram-negative":[225],"biofilms,":[226],"activity,":[229],"LPS-neutralization":[231],"assays":[232],"confirmed":[233],"its":[235,245],"potency":[237],"is,":[238],"least":[240],"part,":[242],"attributable":[243],"stronger":[246],"binding":[248],"affinity.":[249]},"counts_by_year":[],"updated_date":"2026-11-08T12:12:28.789561","created_date":"2026-10-22T00:00:00"}