{"id":"https://openalex.org/W7223174236","doi":"https://doi.org/10.18502/jovr.v21.19965","title":"Unilateral Angle Closure as the Initial Presentation of Multiple Myeloma Metastasis","display_name":"Unilateral Angle Closure as the Initial Presentation of Multiple Myeloma Metastasis","publication_year":2026,"publication_date":"2026-10-22","ids":{"openalex":"https://openalex.org/W7223174236","doi":"https://doi.org/10.18502/jovr.v21.19965","pmid":"https://pubmed.ncbi.nlm.nih.gov/43011673","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/13749109"},"language":"en","primary_location":{"id":"doi:10.18502/jovr.v21.19965","doi":"https://doi.org/10.18502/jovr.v21.19965","is_oa":true,"landing_page_url":"https://doi.org/10.18502/jovr.v21.19965","pdf_url":null,"source":{"id":"https://openalex.org/S2764519907","display_name":"Journal of Ophthalmic and Vision Research","issn_l":"2008-322X","issn":["2008-322X","2008-2010"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-d","doyens","jufo-1","norway-1","poland-70","russia-white-list-2"],"host_organization":"https://openalex.org/P4310319396","host_organization_name":"Knowledge E","host_organization_lineage":["https://openalex.org/P4310319396"],"host_organization_lineage_names":["Knowledge E"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Ophthalmic and Vision Research","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://doi.org/10.18502/jovr.v21.19965","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5159230687","display_name":"Thao Huong Nguyen","orcid":"https://orcid.org/0009-0002-5069-981X","observed_orcids":["https://orcid.org/0009-0002-5069-981X"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Thao Huong Nguyen","raw_affiliation_strings":["Ho Chi Minh City Eye Hospital, Xuan Hoa Ward, Ho Chi Minh City, Vietnam"],"raw_orcid":"https://orcid.org/0009-0002-5069-981X","affiliations":[{"raw_affiliation_string":"Ho Chi Minh City Eye Hospital, Xuan Hoa Ward, Ho Chi Minh City, Vietnam","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5125539582","display_name":"Truong Dang Minh Pham","orcid":"https://orcid.org/0009-0007-2374-8408","observed_orcids":["https://orcid.org/0009-0007-2374-8408"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Truong Dang Minh Pham","raw_affiliation_strings":["Ho Chi Minh City Eye Hospital, Xuan Hoa Ward, Ho Chi Minh City, Vietnam"],"raw_orcid":"https://orcid.org/0009-0007-2374-8408","affiliations":[{"raw_affiliation_string":"Ho Chi Minh City Eye Hospital, Xuan Hoa Ward, Ho Chi Minh City, Vietnam","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5096199662","display_name":"Thanh Nghi\u1ec7p Trang","orcid":"https://orcid.org/0009-0003-6875-3498","observed_orcids":["https://orcid.org/0009-0003-6875-3498"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Thanh Nghiep Trang","raw_affiliation_strings":["Ho Chi Minh City Eye Hospital, Xuan Hoa Ward, Ho Chi Minh City, Vietnam"],"raw_orcid":"https://orcid.org/0009-0003-6875-3498","affiliations":[{"raw_affiliation_string":"Ho Chi Minh City Eye Hospital, Xuan Hoa Ward, Ho Chi Minh City, Vietnam","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5159226659","display_name":"Ngoc Phuong Vy Ly","orcid":"https://orcid.org/0009-0002-6827-510X","observed_orcids":["https://orcid.org/0009-0002-6827-510X"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Ngoc Phuong Vy Ly","raw_affiliation_strings":["Ho Chi Minh City Eye Hospital, Xuan Hoa Ward, Ho Chi Minh City, Vietnam"],"raw_orcid":"https://orcid.org/0009-0002-6827-510X","affiliations":[{"raw_affiliation_string":"Ho Chi Minh City Eye Hospital, Xuan Hoa Ward, Ho Chi Minh City, Vietnam","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5125452103","display_name":"H\u1ed3ng \u00dd Hu\u1ef3nh","orcid":"https://orcid.org/0009-0008-2926-4997","observed_orcids":["https://orcid.org/0009-0008-2926-4997"]},"institutions":[{"id":"https://openalex.org/I18550681","display_name":"Pham Ngoc Thach University of Medicine","ror":"https://ror.org/003g49r03","country_code":"VN","type":"education","lineage":["https://openalex.org/I18550681"]}],"countries":["VN"],"is_corresponding":false,"raw_author_name":"Hong Y Huynh","raw_affiliation_strings":["Pham Ngoc Thach University of Medicine, Hoa Hung Ward, Ho Chi Minh City, Vietnam"],"raw_orcid":"https://orcid.org/0009-0008-2926-4997","affiliations":[{"raw_affiliation_string":"Pham Ngoc Thach University of Medicine, Hoa Hung Ward, Ho Chi Minh City, Vietnam","institution_ids":["https://openalex.org/I18550681"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":200,"currency":"USD","value_usd":200},"apc_paid":{"value":200,"currency":"USD","value_usd":200},"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.0,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"21","issue":null,"first_page":"1","last_page":"9"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10649","display_name":"Multiple Myeloma Research and Treatments","score":0.5922999978065491,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10649","display_name":"Multiple Myeloma Research and Treatments","score":0.5922999978065491,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11328","display_name":"Ocular Oncology and Treatments","score":0.40230000019073486,"subfield":{"id":"https://openalex.org/subfields/2731","display_name":"Ophthalmology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T13467","display_name":"Drug-Induced Ocular Toxicity","score":0.0024999999441206455,"subfield":{"id":"https://openalex.org/subfields/2731","display_name":"Ophthalmology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/multiple-myeloma","display_name":"multiple myeloma","score":0.9980000257492065},{"id":"https://openalex.org/keywords/ocular-metastasis","display_name":"ocular metastasis","score":0.8259999752044678},{"id":"https://openalex.org/keywords/angle-closure-glaucoma","display_name":"angle-closure glaucoma","score":0.8820000290870667},{"id":"https://openalex.org/keywords/ocular-hypertension","display_name":"ocular hypertension","score":0.9570000171661377},{"id":"https://openalex.org/keywords/choroidal-metastases","display_name":"choroidal metastasis","score":0.7260000109672546},{"id":"https://openalex.org/keywords/ciliary-body-cysts","display_name":"ciliary body cysts","score":0.9010000228881836},{"id":"https://openalex.org/keywords/proptosis","display_name":"proptosis","score":0.8809999823570251},{"id":"https://openalex.org/keywords/retinal-detachment","display_name":"retinal detachment","score":0.8029999732971191},{"id":"https://openalex.org/keywords/choroidal-detachment","display_name":"choroidal detachment","score":0.9390000104904175},{"id":"https://openalex.org/keywords/glaucoma-treatment","display_name":"glaucoma treatment","score":0.6669999957084656},{"id":"https://openalex.org/keywords/orbital-metastases","display_name":"orbital metastasis","score":0.4950000047683716}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9847999811172485},{"id":"https://openalex.org/C2776364478","wikidata":"https://www.wikidata.org/wiki/Q467635","display_name":"Multiple myeloma","level":2,"score":0.7138000130653381},{"id":"https://openalex.org/C143409427","wikidata":"https://www.wikidata.org/wiki/Q161238","display_name":"Magnetic resonance imaging","level":2,"score":0.636900007724762},{"id":"https://openalex.org/C2777601897","wikidata":"https://www.wikidata.org/wiki/Q3409113","display_name":"Presentation (obstetrics)","level":2,"score":0.5787000060081482},{"id":"https://openalex.org/C126838900","wikidata":"https://www.wikidata.org/wiki/Q77604","display_name":"Radiology","level":1,"score":0.4537999927997589},{"id":"https://openalex.org/C118487528","wikidata":"https://www.wikidata.org/wiki/Q161437","display_name":"Ophthalmology","level":1,"score":0.41290000081062317},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.39959999918937683},{"id":"https://openalex.org/C2778434524","wikidata":"https://www.wikidata.org/wiki/Q1048080","display_name":"Ciliary body","level":2,"score":0.39169999957084656},{"id":"https://openalex.org/C2779013556","wikidata":"https://www.wikidata.org/wiki/Q181876","display_name":"Metastasis","level":3,"score":0.38420000672340393},{"id":"https://openalex.org/C2778257484","wikidata":"https://www.wikidata.org/wiki/Q555066","display_name":"Visual acuity","level":2,"score":0.36419999599456787},{"id":"https://openalex.org/C2780849966","wikidata":"https://www.wikidata.org/wiki/Q170758","display_name":"Lymph node","level":2,"score":0.3544999957084656},{"id":"https://openalex.org/C3019796121","wikidata":"https://www.wikidata.org/wiki/Q5048356","display_name":"Case presentation","level":2,"score":0.34700000286102295},{"id":"https://openalex.org/C2781092963","wikidata":"https://www.wikidata.org/wiki/Q650050","display_name":"Intraocular pressure","level":2,"score":0.3215999901294708},{"id":"https://openalex.org/C2779159986","wikidata":"https://www.wikidata.org/wiki/Q4930803","display_name":"Blurred vision","level":2,"score":0.3179999887943268},{"id":"https://openalex.org/C527108885","wikidata":"https://www.wikidata.org/wiki/Q835153","display_name":"Physical examination","level":2,"score":0.25850000977516174},{"id":"https://openalex.org/C2776148792","wikidata":"https://www.wikidata.org/wiki/Q3041498","display_name":"Eye disease","level":2,"score":0.2547999918460846},{"id":"https://openalex.org/C38298161","wikidata":"https://www.wikidata.org/wiki/Q1207920","display_name":"Derangement","level":2,"score":0.251800000667572}],"mesh":[],"locations_count":3,"locations":[{"id":"doi:10.18502/jovr.v21.19965","doi":"https://doi.org/10.18502/jovr.v21.19965","is_oa":true,"landing_page_url":"https://doi.org/10.18502/jovr.v21.19965","pdf_url":null,"source":{"id":"https://openalex.org/S2764519907","display_name":"Journal of Ophthalmic and Vision Research","issn_l":"2008-322X","issn":["2008-322X","2008-2010"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-d","doyens","jufo-1","norway-1","poland-70","russia-white-list-2"],"host_organization":"https://openalex.org/P4310319396","host_organization_name":"Knowledge E","host_organization_lineage":["https://openalex.org/P4310319396"],"host_organization_lineage_names":["Knowledge E"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Ophthalmic and Vision Research","raw_type":"journal-article"},{"id":"pmid:43011673","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/43011673","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of ophthalmic & vision research","raw_type":"Case Reports"},{"id":"pmh:oai:doaj.org/article:be9ebed8faf64a9cbc160c9e6c6f7153","doi":null,"is_oa":false,"landing_page_url":"https://doaj.org/article/be9ebed8faf64a9cbc160c9e6c6f7153","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Journal of Ophthalmic & Vision Research, Vol 21 (2026)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.18502/jovr.v21.19965","doi":"https://doi.org/10.18502/jovr.v21.19965","is_oa":true,"landing_page_url":"https://doi.org/10.18502/jovr.v21.19965","pdf_url":null,"source":{"id":"https://openalex.org/S2764519907","display_name":"Journal of Ophthalmic and Vision Research","issn_l":"2008-322X","issn":["2008-322X","2008-2010"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-d","doyens","jufo-1","norway-1","poland-70","russia-white-list-2"],"host_organization":"https://openalex.org/P4310319396","host_organization_name":"Knowledge E","host_organization_lineage":["https://openalex.org/P4310319396"],"host_organization_lineage_names":["Knowledge E"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Ophthalmic and Vision Research","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.9940000176429749}],"study_designs":[{"id":"https://openalex.org/study-designs/case-report","display_name":"Case Report"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":21,"referenced_works":["https://openalex.org/W1980222117","https://openalex.org/W2002567411","https://openalex.org/W2016250924","https://openalex.org/W2040078972","https://openalex.org/W2055465308","https://openalex.org/W2061792610","https://openalex.org/W2069014463","https://openalex.org/W2072493037","https://openalex.org/W2094377588","https://openalex.org/W2144728882","https://openalex.org/W2161185780","https://openalex.org/W2167491188","https://openalex.org/W2334549976","https://openalex.org/W2493714412","https://openalex.org/W2555309053","https://openalex.org/W2791021848","https://openalex.org/W2807642471","https://openalex.org/W2983161385","https://openalex.org/W2995346138","https://openalex.org/W3111083953","https://openalex.org/W4286567508"],"related_works":["https://openalex.org/W2055465308","https://openalex.org/W2418038752","https://openalex.org/W1975659494","https://openalex.org/W4408434817","https://openalex.org/W4392003698","https://openalex.org/W4404118230","https://openalex.org/W2072493037","https://openalex.org/W2278040164","https://openalex.org/W2061792610","https://openalex.org/W4402112448"],"abstract_inverted_index":{"Purpose:":[0],"Ocular":[1],"manifestations":[2],"of":[3,14,63,148],"multiple":[4,85],"myeloma":[5],"(MM)":[6],"are":[7],"rare":[8],"but":[9],"may":[10],"affect":[11],"all":[12],"tissues":[13],"the":[15],"eye.":[16],"This":[17],"report":[18],"describes":[19],"a":[20,89,113],"patient":[21,47,120],"with":[22,27,48,53,74,105,140],"recurrent":[23,103],"MM":[24,51,104,133,141],"initially":[25],"presenting":[26],"ocular":[28,149],"hypertension":[29],"due":[30],"to":[31,123,129],"angle":[32,80],"closure,":[33],"revealing":[34],"extensive":[35],"ocular,":[36],"orbital,":[37],"and":[38,59,78,93,109,112,126],"systemic":[39],"metastatic":[40],"disease.":[41],"Case":[42],"Report:":[43],"A":[44],"54-year-old":[45],"female":[46],"previously":[49],"treated":[50],"presented":[52],"left":[54],"eye":[55],"pain,":[56],"blurred":[57],"vision,":[58],"an":[60],"intraocular":[61],"pressure":[62],"38":[64],"mmHg.":[65],"Examination":[66],"revealed":[67],"proptosis,":[68],"restricted":[69],"upward":[70],"gaze,":[71],"conjunctival":[72],"injection":[73],"two":[75],"salmon-patch":[76],"lesions,":[77],"complete":[79],"closure.":[81],"Further":[82],"findings":[83],"included":[84],"ciliary":[86],"body":[87],"cysts,":[88],"massive":[90],"choroidal":[91],"mass,":[92],"retinal/choroidal":[94],"detachments.":[95],"She":[96],"had":[97],"pancytopenia.":[98],"Magnetic":[99],"resonance":[100],"imaging":[101],"confirmed":[102],"superior":[106],"rectus":[107],"muscle":[108],"spine":[110],"infiltrations,":[111],"large":[114],"prevertebral":[115],"lymph":[116],"node":[117],"mass.":[118],"The":[119],"responded":[121],"well":[122],"antiglaucoma":[124],"medications":[125],"was":[127],"referred":[128],"her":[130],"oncologist.":[131],"Conclusion:":[132],"can":[134],"involve":[135],"various":[136],"ophthalmic":[137],"structures.":[138],"Patients":[139],"require":[142],"regular":[143],"examinations":[144],"for":[145],"early":[146],"detection":[147],"metastasis.":[150]},"counts_by_year":[],"updated_date":"2026-11-12T12:28:57.059296","created_date":"2026-10-22T00:00:00"}