{"id":"https://openalex.org/W7223159348","doi":"https://doi.org/10.1016/j.htct.2026.107170","title":"TEND\u00caNCIA TEMPORAL DOS MARCADORES SOROL\u00d3GICOS REAGENTES EM DOADORES DE SANGUE: AN\u00c1LISE DE CINCO ANOS NO HEMON\u00daCLEO DE BARRETOS","display_name":"TEND\u00caNCIA TEMPORAL DOS MARCADORES SOROL\u00d3GICOS REAGENTES EM DOADORES DE SANGUE: AN\u00c1LISE DE CINCO ANOS NO HEMON\u00daCLEO DE BARRETOS","publication_year":2026,"publication_date":"2026-10-01","ids":{"openalex":"https://openalex.org/W7223159348","doi":"https://doi.org/10.1016/j.htct.2026.107170"},"language":"en","primary_location":{"id":"doi:10.1016/j.htct.2026.107170","doi":"https://doi.org/10.1016/j.htct.2026.107170","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.htct.2026.107170","pdf_url":"https://www.sciencedirect.com/science/article/pii/S253113792600917X/pdf","source":{"id":"https://openalex.org/S2898598332","display_name":"Hematology Transfusion and Cell Therapy","issn_l":"2531-1379","issn":["2531-1379","2531-1387"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","ki-jl-1","poland-20","russia-white-list-3","scielo"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Hematology, Transfusion and Cell Therapy","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj"],"open_access":{"is_oa":true,"oa_status":"diamond","oa_url":"https://www.sciencedirect.com/science/article/pii/S253113792600917X/pdf","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5014534916","display_name":"Fernanda Silva Gomes","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Fernanda Silva GOMES","raw_affiliation_strings":["Hospital de Amor, Barretos, SP, Brasil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Hospital de Amor, Barretos, SP, Brasil","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5159196426","display_name":"Bruna Helena Ribeiro SILVA","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Bruna Helena Ribeiro SILVA","raw_affiliation_strings":["Hospital de Amor, Barretos, SP, Brasil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Hospital de Amor, Barretos, SP, Brasil","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5159189807","display_name":"Milena Santos MAIA","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Milena Santos MAIA","raw_affiliation_strings":["Hospital de Amor, Barretos, SP, Brasil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Hospital de Amor, Barretos, SP, Brasil","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5094112917","display_name":"L\u00edvia Cristina Ferreira De Oliveira","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"L\u00edvia Cristina Ferreira OLIVEIRA","raw_affiliation_strings":["Hospital de Amor, Barretos, SP, Brasil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Hospital de Amor, Barretos, SP, Brasil","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5159170178","display_name":"Alessandra Degrande PETTA","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Alessandra Degrande PETTA","raw_affiliation_strings":["Hospital de Amor, Barretos, SP, Brasil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Hospital de Amor, Barretos, SP, Brasil","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5159194306","display_name":"Vanessa Almeida P\u00c1DUA","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Vanessa Almeida P\u00c1DUA","raw_affiliation_strings":["Hospital de Amor, Barretos, SP, Brasil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Hospital de Amor, Barretos, SP, Brasil","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5049585432","display_name":"Giuliana Martinelli Dotoli","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Giuliana Martinelli DOTOLI","raw_affiliation_strings":["Hospital de Amor, Barretos, SP, Brasil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Hospital de Amor, Barretos, SP, Brasil","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":0,"currency":"USD","value_usd":0},"apc_paid":null,"fwci":0.0,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":{"value":0.80502076,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"48","issue":null,"first_page":"107170","last_page":"107170"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12735","display_name":"Blood donation and transfusion practices","score":0.9301999807357788,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T12735","display_name":"Blood donation and transfusion practices","score":0.9301999807357788,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11314","display_name":"Clinical Laboratory Practices and Quality Control","score":0.020800000056624413,"subfield":{"id":"https://openalex.org/subfields/3607","display_name":"Medical Laboratory Technology"},"field":{"id":"https://openalex.org/fields/36","display_name":"Health Professions"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11660","display_name":"Blood groups and transfusion","score":0.005900000222027302,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/blood-donor-screening","display_name":"blood donor screening","score":0.7110000252723694},{"id":"https://openalex.org/keywords/serological-markers","display_name":"serological markers","score":0.6700000166893005},{"id":"https://openalex.org/keywords/temporal-trends","display_name":"temporal trends","score":0.8820000290870667},{"id":"https://openalex.org/keywords/hiv","display_name":"HIV","score":0.6809999942779541},{"id":"https://openalex.org/keywords/hepatitis-b","display_name":"hepatitis B","score":0.8880000114440918},{"id":"https://openalex.org/keywords/hepatitis-c","display_name":"hepatitis C","score":0.9869999885559082},{"id":"https://openalex.org/keywords/htlv","display_name":"HTLV","score":0.8109999895095825},{"id":"https://openalex.org/keywords/syphilis","display_name":"syphilis","score":0.9950000047683716},{"id":"https://openalex.org/keywords/chagas-disease","display_name":"Chagas disease","score":0.9900000095367432},{"id":"https://openalex.org/keywords/transfusion-safety","display_name":"transfusion safety","score":0.8240000009536743},{"id":"https://openalex.org/keywords/disease-surveillance","display_name":"disease surveillance","score":0.6639999747276306},{"id":"https://openalex.org/keywords/exponential-regression","display_name":"exponential regression","score":0.6309999823570251}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.7497000098228455},{"id":"https://openalex.org/C15708023","wikidata":"https://www.wikidata.org/wiki/Q80083","display_name":"Humanities","level":1,"score":0.16529999673366547},{"id":"https://openalex.org/C523008124","wikidata":"https://www.wikidata.org/wiki/Q5357996","display_name":"Electrodiagnosis","level":2,"score":0.1388999968767166},{"id":"https://openalex.org/C2779473830","wikidata":"https://www.wikidata.org/wiki/Q1540899","display_name":"MEDLINE","level":2,"score":0.12610000371932983},{"id":"https://openalex.org/C29456083","wikidata":"https://www.wikidata.org/wiki/Q1221899","display_name":"Gynecology","level":1,"score":0.12479999661445618},{"id":"https://openalex.org/C2992981700","wikidata":"https://www.wikidata.org/wiki/Q727096","display_name":"Congenital disease","level":2,"score":0.12250000238418579},{"id":"https://openalex.org/C2989005","wikidata":"https://www.wikidata.org/wiki/Q214963","display_name":"Nuclear medicine","level":1,"score":0.08969999849796295},{"id":"https://openalex.org/C99508421","wikidata":"https://www.wikidata.org/wiki/Q2678675","display_name":"Physical medicine and rehabilitation","level":1,"score":0.07999999821186066},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.0731000006198883},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.07020000368356705}],"mesh":[],"locations_count":2,"locations":[{"id":"doi:10.1016/j.htct.2026.107170","doi":"https://doi.org/10.1016/j.htct.2026.107170","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.htct.2026.107170","pdf_url":"https://www.sciencedirect.com/science/article/pii/S253113792600917X/pdf","source":{"id":"https://openalex.org/S2898598332","display_name":"Hematology Transfusion and Cell Therapy","issn_l":"2531-1379","issn":["2531-1379","2531-1387"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","ki-jl-1","poland-20","russia-white-list-3","scielo"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Hematology, Transfusion and Cell Therapy","raw_type":"journal-article"},{"id":"pmh:oai:doaj.org/article:f68e0a73288240878507eb156b2c8f4d","doi":null,"is_oa":false,"landing_page_url":"https://doaj.org/article/f68e0a73288240878507eb156b2c8f4d","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Hematology, Transfusion and Cell Therapy, Vol 48, Iss , Pp 107170- (2026)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.1016/j.htct.2026.107170","doi":"https://doi.org/10.1016/j.htct.2026.107170","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.htct.2026.107170","pdf_url":"https://www.sciencedirect.com/science/article/pii/S253113792600917X/pdf","source":{"id":"https://openalex.org/S2898598332","display_name":"Hematology Transfusion and Cell Therapy","issn_l":"2531-1379","issn":["2531-1379","2531-1387"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","ki-jl-1","poland-20","russia-white-list-3","scielo"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Hematology, Transfusion and Cell Therapy","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.9476000070571899,"display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W7223159348.pdf","grobid_xml":"https://content.openalex.org/works/W7223159348.grobid-xml"},"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W4403568299","https://openalex.org/W4387748542","https://openalex.org/W4415671064","https://openalex.org/W4415670676","https://openalex.org/W7223108182","https://openalex.org/W4403568308","https://openalex.org/W4415669345","https://openalex.org/W4403568636","https://openalex.org/W4387747937","https://openalex.org/W4403568443"],"abstract_inverted_index":{"Introdu\u00e7\u00e3o":[0],"A":[1,163,325,384,420],"triagem":[2,91,506],"sorol\u00f3gica":[3,92,269,400,485],"constitui":[4],"uma":[5,61,434],"etapa":[6],"essencial":[7],"para":[8,43,142,197,431,502],"a":[9,13,44,82,105,180,267,440,459],"seguran\u00e7a":[10,509],"transfusional,":[11],"permitindo":[12],"identifica\u00e7\u00e3o":[14],"de":[15,28,32,34,36,48,51,64,93,95,99,103,119,123,128,133,137,155,175,187,191,220,290,305,398,407,416,476,483,486],"infec\u00e7\u00f5es":[16],"transmiss\u00edveis":[17],"pelo":[18],"sangue,":[19,221],"em":[20,239,245,251,258,423,444],"conformidade":[21],"com":[22,114,272,403,427,437],"os":[23,57,466],"crit\u00e9rios":[24],"estabelecidos":[25],"pela":[26,321],"Portaria":[27],"Consolida\u00e7\u00e3o":[29],"n\u00ba":[30],"5,":[31],"28":[33],"setembro":[35],"2017,":[37],"do":[38,70,78,117,121,199,203,371,392,474,493],"Minist\u00e9rio":[39],"da":[40,472,505,508],"Sa\u00fade,":[41],"contribuindo":[42],"prote\u00e7\u00e3o":[45],"dos":[46,85,386,401],"receptores":[47],"hemocomponentes.":[49],"Al\u00e9m":[50],"sua":[52],"relev\u00e2ncia":[53],"na":[54,73,90,161],"pr\u00e1tica":[55],"assistencial,":[56],"resultados":[58,140,154,233,387],"sorol\u00f3gicos":[59,87,388],"representam":[60],"importante":[62],"ferramenta":[63],"vigil\u00e2ncia":[65],"epidemiol\u00f3gica,":[66],"possibilitando":[67],"o":[68,185,315,329,414,489,503],"monitoramento":[69,497],"seu":[71],"perfil":[72,397],"popula\u00e7\u00e3o":[74],"doadora":[75],"ao":[76,294,390,411,470],"longo":[77,391],"tempo.":[79],"Objetivo":[80],"Analisar":[81],"tend\u00eancia":[83,181,273,379],"temporal":[84,182],"marcadores":[86,376,454],"reagentes":[88,141,234,389,448],"identificados":[89],"doadores":[94],"sangue":[96,129],"no":[97,101,396],"Hemon\u00facleo":[98,122],"Barretos,":[100],"per\u00edodo":[102,393],"2021":[104,134,213],"2025.":[106],"Metodologia":[107],"Estudo":[108],"retrospectivo,":[109],"observacional":[110],"e":[111,135,151,169,173,190,195,214,287,348,382,425,449,507],"anal\u00edtico,":[112],"realizado":[113],"dados":[115],"secund\u00e1rios":[116],"setor":[118],"sorologia":[120,226],"Barretos.":[124],"Foram":[125],"analisadas":[126],"doa\u00e7\u00f5es":[127,219,306,417],"realizadas":[130,217],"entre":[131,236,243,249,255,262,465],"janeiro":[132],"dezembro":[136],"2025,":[138,215,259],"considerando":[139],"HIV,":[143],"HBsAg,":[144],"Anti-HBc,":[145],"Anti-HCV,":[146],"HTLV":[147],"I/II,":[148],"s\u00edfilis":[149,322],"(VDRL)":[150,323],"Chagas.":[152],"Os":[153,374,452],"segunda":[156],"amostra":[157],"n\u00e3o":[158,377,462],"foram":[159,216],"inclu\u00eddos":[160],"avalia\u00e7\u00e3o.":[162],"an\u00e1lise":[164,326],"descritiva":[165],"utilizou":[166],"frequ\u00eancias":[167],"absolutas":[168],"relativas,":[170],"distribui\u00e7\u00e3o":[171],"anual":[172,304],"propor\u00e7\u00e3o":[174],"positividade":[176,268],"sorol\u00f3gica.":[177],"Para":[178],"avaliar":[179],"(2021\u20132025),":[183],"aplicou-se":[184],"teste":[186],"Associa\u00e7\u00e3o":[188],"Linear-Linear":[189],"regress\u00e3o":[192],"linear":[193],"simples":[194],"exponencial":[196,429],"quantifica\u00e7\u00e3o":[198],"decr\u00e9scimo,":[200],"por":[201,369],"meio":[202],"software":[204],"IBM":[205],"SPSS":[206],"Statistics":[207],"(p":[208,309],"<":[209,285],"0,05).":[210],"Resultados":[211],"Entre":[212],"64.964":[218],"das":[222],"quais":[223],"1.015":[224],"apresentaram":[225,378],"reagente":[227],"(1,6%).":[228],"Em":[229,468],"2021,":[230],"ocorreram":[231],"301":[232],"(2,4%)":[235],"12.347":[237],"doa\u00e7\u00f5es;":[238],"2022,":[240],"223":[241],"(1,7%)":[242],"12.965;":[244],"2023,":[246],"185":[247],"(1,4%)":[248],"13.125;":[250],"2024,":[252],"155":[253],"(1,2%)":[254],"13.283;":[256],"e,":[257],"151":[260],"(1,1%)":[261],"13.244":[263],"doa\u00e7\u00f5es.":[264],"No":[265],"per\u00edodo,":[266],"reduziu":[270],"54,2%,":[271],"decrescente":[274],"significativa":[275],"(Associa\u00e7\u00e3o":[276],"Linear-Linear:":[277],"\u03c7\u00b2":[278],"=":[279,282,297,300,310,333,336,339,343,346,352,355,358,362,365],"81,334;":[280],"gl":[281],"1;":[283],"p":[284,338,345,357,364],"0,001)":[286],"redu\u00e7\u00e3o":[288,385,460],"m\u00e9dia":[289],"0,31":[291,408],"ponto":[292,409],"percentual":[293,410],"ano":[295],"(B":[296],"-0,310;":[298],"R\u00b2":[299,335,342,354,361],"0,880).":[301],"O":[302,312,496],"n\u00famero":[303,415],"manteve-se":[307,491],"est\u00e1vel":[308],"0,052).":[311],"Anti-HBc":[313,330,424],"foi":[314,463],"marcador":[316],"mais":[317],"frequente":[318],"(35,1%),":[319],"seguido":[320],"(30,4%),":[324],"estratificada":[327],"identificou":[328],"(linear:":[331,350],"B":[332,351],"\u22120,167;":[334],"0,784;":[337],"0,046;":[340],"exponencial:":[341,360],"0,894;":[344],"0,015)":[347],"VDRL":[349],"\u22120,141;":[353],"0,855;":[356],"0,024;":[359],"0,931;":[363],"0,008)":[366],"como":[367],"respons\u00e1veis":[368],"99,4%":[370],"decl\u00ednio":[372,404],"total.":[373],"demais":[375,453],"significativa.":[380],"Discuss\u00e3o":[381],"conclus\u00e3o":[383],"indica":[394],"melhora":[395],"inaptid\u00e3o":[399,484],"doadores,":[402],"m\u00e9dio":[405],"significativo":[406],"ano,":[412],"enquanto":[413],"permaneceu":[418],"est\u00e1vel.":[419],"queda":[421],"concentrou-se":[422],"VDRL,":[426],"ajuste":[428],"superior":[430],"ambos,":[432],"sugerindo":[433],"desacelera\u00e7\u00e3o":[435],"(2024-2025)":[436],"poss\u00edvel":[438],"aproxima\u00e7\u00e3o":[439],"taxas":[441],"residuais":[442],"(infec\u00e7\u00f5es":[443],"janela":[445],"imunol\u00f3gica,":[446],"falsos":[447],"casos":[450],"end\u00eamicos).":[451],"permaneceram":[455],"est\u00e1veis,":[456],"indicando":[457],"que":[458,480],"global":[461],"uniforme":[464],"par\u00e2metros.":[467],"compara\u00e7\u00e3o":[469],"par\u00e2metro":[471],"Hemorrede":[473],"Estado":[475],"S\u00e3o":[477],"Paulo":[478],"(2011),":[479],"estabelece":[481],"taxa":[482],"at\u00e9":[487],"2,5%,":[488],"servi\u00e7o":[490],"dentro":[492],"limite":[494],"recomendado.":[495],"cont\u00ednuo":[498],"desses":[499],"indicadores":[500],"contribui":[501],"aprimoramento":[504],"transfusional.":[510]},"counts_by_year":[],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2026-10-22T00:00:00"}