{"id":"https://openalex.org/W7223157696","doi":"https://doi.org/10.3389/fped.2026.1986840","title":"Divergent PICU lengths of stay despite identical phoenix sepsis scores: heterogeneity in pediatric sepsis outcomes according to system involvement profiles","display_name":"Divergent PICU lengths of stay despite identical phoenix sepsis scores: heterogeneity in pediatric sepsis outcomes according to system involvement profiles","publication_year":2026,"publication_date":"2026-10-21","ids":{"openalex":"https://openalex.org/W7223157696","doi":"https://doi.org/10.3389/fped.2026.1986840","pmid":"https://pubmed.ncbi.nlm.nih.gov/42984736","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/13731310"},"language":"en","primary_location":{"id":"doi:10.3389/fped.2026.1986840","doi":"https://doi.org/10.3389/fped.2026.1986840","is_oa":true,"landing_page_url":"https://doi.org/10.3389/fped.2026.1986840","pdf_url":"https://www.frontiersin.org/journals/pediatrics/articles/10.3389/fped.2026.1986840/pdf","source":{"id":"https://openalex.org/S2596117549","display_name":"Frontiers in Pediatrics","issn_l":"2296-2360","issn":["2296-2360"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","norway-1","poland-70","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320527","host_organization_name":"Frontiers Media","host_organization_lineage":["https://openalex.org/P4310320527"],"host_organization_lineage_names":["Frontiers Media"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in Pediatrics","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://www.frontiersin.org/journals/pediatrics/articles/10.3389/fped.2026.1986840/pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5159209285","display_name":"Zhen Jiang","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210124723","display_name":"Maternal and Child Health Hospital of Sichuan Province","ror":"https://ror.org/02taaxx56","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210124723"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Zhen Jiang","raw_affiliation_strings":["Department of Pediatric Critical Care Medicine, Sichuan Provincial Maternity and Child Health Care Hospital"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pediatric Critical Care Medicine, Sichuan Provincial Maternity and Child Health Care Hospital","institution_ids":["https://openalex.org/I4210124723"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5153656462","display_name":"Lijuan Wu","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210124723","display_name":"Maternal and Child Health Hospital of Sichuan Province","ror":"https://ror.org/02taaxx56","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210124723"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Lijuan Wu","raw_affiliation_strings":["Department of Pediatric Critical Care Medicine, Sichuan Provincial Maternity and Child Health Care Hospital"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pediatric Critical Care Medicine, Sichuan Provincial Maternity and Child Health Care Hospital","institution_ids":["https://openalex.org/I4210124723"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5159202199","display_name":"Xinyue Zhou","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210124723","display_name":"Maternal and Child Health Hospital of Sichuan Province","ror":"https://ror.org/02taaxx56","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210124723"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Xinyue Zhou","raw_affiliation_strings":["Department of Pediatric Critical Care Medicine, Sichuan Provincial Maternity and Child Health Care Hospital"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pediatric Critical Care Medicine, Sichuan Provincial Maternity and Child Health Care Hospital","institution_ids":["https://openalex.org/I4210124723"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5139538781","display_name":"Jing Xu","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210124723","display_name":"Maternal and Child Health Hospital of Sichuan Province","ror":"https://ror.org/02taaxx56","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210124723"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Jing Xu","raw_affiliation_strings":["Department of Pediatric Critical Care Medicine, Sichuan Provincial Maternity and Child Health Care Hospital"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pediatric Critical Care Medicine, Sichuan Provincial Maternity and Child Health Care Hospital","institution_ids":["https://openalex.org/I4210124723"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5029699332","display_name":"Xiaxia Xiong","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210124723","display_name":"Maternal and Child Health Hospital of Sichuan Province","ror":"https://ror.org/02taaxx56","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210124723"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Xiaxia Xiong","raw_affiliation_strings":["Department of Pediatric Critical Care Medicine, Sichuan Provincial Maternity and Child Health Care Hospital"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pediatric Critical Care Medicine, Sichuan Provincial Maternity and Child Health Care Hospital","institution_ids":["https://openalex.org/I4210124723"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5139520879","display_name":"Jian Chen","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210124723","display_name":"Maternal and Child Health Hospital of Sichuan Province","ror":"https://ror.org/02taaxx56","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210124723"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Jian Chen","raw_affiliation_strings":["Department of Pediatric Critical Care Medicine, Sichuan Provincial Maternity and Child Health Care Hospital"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pediatric Critical Care Medicine, Sichuan Provincial Maternity and Child Health Care Hospital","institution_ids":["https://openalex.org/I4210124723"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5153626914","display_name":"Yuhang Hu","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210124723","display_name":"Maternal and Child Health Hospital of Sichuan Province","ror":"https://ror.org/02taaxx56","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210124723"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Yuhang Hu","raw_affiliation_strings":["Department of Pediatric Critical Care Medicine, Sichuan Provincial Maternity and Child Health Care Hospital"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pediatric Critical Care Medicine, Sichuan Provincial Maternity and Child Health Care Hospital","institution_ids":["https://openalex.org/I4210124723"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5139520879","https://openalex.org/A5153626914"],"corresponding_institution_ids":["https://openalex.org/I4210124723"],"apc_list":{"value":3150,"currency":"CHF","value_usd":3801},"apc_paid":{"value":3150,"currency":"CHF","value_usd":3801},"fwci":0.0,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":{"value":0.80708356,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"14","issue":null,"first_page":"1986840","last_page":"1986840"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10218","display_name":"Sepsis Diagnosis and Treatment","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2706","display_name":"Critical Care and Intensive Care Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10218","display_name":"Sepsis Diagnosis and Treatment","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2706","display_name":"Critical Care and Intensive Care Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T14165","display_name":"Inflammation biomarkers and pathways","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10684","display_name":"Acute Kidney Injury Research","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2727","display_name":"Nephrology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/sepsis","display_name":"sepsis","score":0.8939999938011169},{"id":"https://openalex.org/keywords/pediatric-sepsis","display_name":"pediatric sepsis","score":0.9399999976158142},{"id":"https://openalex.org/keywords/picu-length-of-stay","display_name":"PICU length of stay","score":0.8690000176429749},{"id":"https://openalex.org/keywords/phoenix-sepsis-score","display_name":"Phoenix Sepsis Score","score":0.9950000047683716},{"id":"https://openalex.org/keywords/multisystem-involvement","display_name":"multisystem involvement","score":0.5260000228881836},{"id":"https://openalex.org/keywords/respiratory-involvement","display_name":"respiratory involvement","score":0.5789999961853027},{"id":"https://openalex.org/keywords/invasive-mechanical-ventilation","display_name":"invasive mechanical ventilation","score":0.8270000219345093},{"id":"https://openalex.org/keywords/sepsis-mortality","display_name":"sepsis mortality","score":0.6110000014305115},{"id":"https://openalex.org/keywords/lactate","display_name":"lactate","score":0.7749999761581421},{"id":"https://openalex.org/keywords/sepsis-scoring-systems","display_name":"sepsis severity scoring","score":0.4339999854564667}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9290000200271606},{"id":"https://openalex.org/C2778384902","wikidata":"https://www.wikidata.org/wiki/Q183134","display_name":"Sepsis","level":2,"score":0.7264000177383423},{"id":"https://openalex.org/C151956035","wikidata":"https://www.wikidata.org/wiki/Q1132755","display_name":"Logistic regression","level":2,"score":0.6283000111579895},{"id":"https://openalex.org/C2777080012","wikidata":"https://www.wikidata.org/wiki/Q3766250","display_name":"Mechanical ventilation","level":2,"score":0.5716000199317932},{"id":"https://openalex.org/C200457457","wikidata":"https://www.wikidata.org/wiki/Q584049","display_name":"Ventilation (architecture)","level":2,"score":0.5200999975204468},{"id":"https://openalex.org/C187212893","wikidata":"https://www.wikidata.org/wiki/Q123028","display_name":"Pediatrics","level":1,"score":0.4390000104904175},{"id":"https://openalex.org/C534529494","wikidata":"https://www.wikidata.org/wiki/Q7891","display_name":"Respiratory system","level":2,"score":0.38940000534057617},{"id":"https://openalex.org/C167135981","wikidata":"https://www.wikidata.org/wiki/Q2146302","display_name":"Retrospective cohort study","level":2,"score":0.35530000925064087},{"id":"https://openalex.org/C194828623","wikidata":"https://www.wikidata.org/wiki/Q2861470","display_name":"Emergency medicine","level":1,"score":0.35089999437332153},{"id":"https://openalex.org/C2779167034","wikidata":"https://www.wikidata.org/wiki/Q27685","display_name":"Phoenix","level":3,"score":0.3352999985218048},{"id":"https://openalex.org/C50440223","wikidata":"https://www.wikidata.org/wiki/Q1475848","display_name":"Risk factor","level":2,"score":0.32670000195503235},{"id":"https://openalex.org/C179755657","wikidata":"https://www.wikidata.org/wiki/Q58702","display_name":"Mortality rate","level":2,"score":0.3179999887943268},{"id":"https://openalex.org/C177713679","wikidata":"https://www.wikidata.org/wiki/Q679690","display_name":"Intensive care medicine","level":1,"score":0.31200000643730164},{"id":"https://openalex.org/C2994086866","wikidata":"https://www.wikidata.org/wiki/Q183134","display_name":"Severe sepsis","level":4,"score":0.3116999864578247},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.310699999332428},{"id":"https://openalex.org/C2776888751","wikidata":"https://www.wikidata.org/wiki/Q767485","display_name":"Respiratory failure","level":2,"score":0.29100000858306885},{"id":"https://openalex.org/C2777984932","wikidata":"https://www.wikidata.org/wiki/Q7336293","display_name":"Risk of mortality","level":2,"score":0.27970001101493835},{"id":"https://openalex.org/C2777785397","wikidata":"https://www.wikidata.org/wiki/Q492194","display_name":"Group B","level":2,"score":0.2703000009059906},{"id":"https://openalex.org/C30036603","wikidata":"https://www.wikidata.org/wiki/Q17125150","display_name":"Severity of illness","level":2,"score":0.26809999346733093}],"mesh":[],"locations_count":4,"locations":[{"id":"doi:10.3389/fped.2026.1986840","doi":"https://doi.org/10.3389/fped.2026.1986840","is_oa":true,"landing_page_url":"https://doi.org/10.3389/fped.2026.1986840","pdf_url":"https://www.frontiersin.org/journals/pediatrics/articles/10.3389/fped.2026.1986840/pdf","source":{"id":"https://openalex.org/S2596117549","display_name":"Frontiers in Pediatrics","issn_l":"2296-2360","issn":["2296-2360"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","norway-1","poland-70","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320527","host_organization_name":"Frontiers Media","host_organization_lineage":["https://openalex.org/P4310320527"],"host_organization_lineage_names":["Frontiers Media"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in Pediatrics","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:13731310","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC13731310/","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC13731310/pdf/fped-14-1986840.pdf","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Front Pediatr","raw_type":"Text"},{"id":"pmid:42984736","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/42984736","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in pediatrics","raw_type":"Journal Article"},{"id":"pmh:oai:doaj.org/article:638f3b3a3fa44ca38a53df57051175e9","doi":null,"is_oa":false,"landing_page_url":"https://doaj.org/article/638f3b3a3fa44ca38a53df57051175e9","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Frontiers in Pediatrics, Vol 14 (2026)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.3389/fped.2026.1986840","doi":"https://doi.org/10.3389/fped.2026.1986840","is_oa":true,"landing_page_url":"https://doi.org/10.3389/fped.2026.1986840","pdf_url":"https://www.frontiersin.org/journals/pediatrics/articles/10.3389/fped.2026.1986840/pdf","source":{"id":"https://openalex.org/S2596117549","display_name":"Frontiers in Pediatrics","issn_l":"2296-2360","issn":["2296-2360"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","norway-1","poland-70","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320527","host_organization_name":"Frontiers Media","host_organization_lineage":["https://openalex.org/P4310320527"],"host_organization_lineage_names":["Frontiers Media"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in Pediatrics","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":1.0,"display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W7223157696.pdf","grobid_xml":"https://content.openalex.org/works/W7223157696.grobid-xml"},"referenced_works_count":31,"referenced_works":["https://openalex.org/W1981940713","https://openalex.org/W2006780009","https://openalex.org/W2037668591","https://openalex.org/W2052233685","https://openalex.org/W2056047588","https://openalex.org/W2076590961","https://openalex.org/W2156828749","https://openalex.org/W2280404143","https://openalex.org/W2553300030","https://openalex.org/W2745212246","https://openalex.org/W2779809707","https://openalex.org/W2790215980","https://openalex.org/W2912650925","https://openalex.org/W2998853022","https://openalex.org/W3208596645","https://openalex.org/W4391062880","https://openalex.org/W4391063005","https://openalex.org/W4403301561","https://openalex.org/W4405950420","https://openalex.org/W4406052576","https://openalex.org/W4406304109","https://openalex.org/W4410040582","https://openalex.org/W4412159692","https://openalex.org/W4412423588","https://openalex.org/W4412651035","https://openalex.org/W4414166677","https://openalex.org/W4417465617","https://openalex.org/W7130537348","https://openalex.org/W7133859366","https://openalex.org/W7140090221","https://openalex.org/W7158912507"],"related_works":["https://openalex.org/W7148673897","https://openalex.org/W7165027312","https://openalex.org/W7092596890","https://openalex.org/W7124135637","https://openalex.org/W4409962689","https://openalex.org/W7223204999","https://openalex.org/W4407812496","https://openalex.org/W4413245074","https://openalex.org/W4414471997","https://openalex.org/W7165184507"],"abstract_inverted_index":{"Objective":[0],"This":[1],"study":[2],"examined":[3],"how":[4],"different":[5,309,315],"subsystem":[6,322],"involvement":[7,96,103,136,311],"patterns":[8,312],"in":[9,263,276],"the":[10,57,86,120,144,155,178,225,243,260,272,277,285,304,335,351,359],"Phoenix":[11,61,286,306,343],"Sepsis":[12],"Score":[13],"relate":[14],"to":[15,48,252],"PICU":[16,51,115,125,185,264,330],"length":[17,126,265],"of":[18,59,93,113,127,141,266,284,328],"stay":[19,116,128,186,231,267],"among":[20],"children":[21,44,302],"with":[22,27,36,45,89,143,303],"sepsis,":[23],"focusing":[24],"on":[25],"patients":[26],"identical":[28,90,169],"total":[29,91,157,170,307,342,360],"scores,":[30,158],"and":[31,77,119,124,161,207,317],"explored":[32],"clinical":[33],"factors":[34],"associated":[35],"these":[37],"differences.":[38],"Methods":[39],"We":[40,83],"retrospectively":[41],"included":[42],"107":[43],"sepsis":[46],"admitted":[47],"a":[49],"single":[50],"(2024\u20132025).":[52],"Patients":[53],"were":[54],"grouped":[55],"by":[56,271,334],"number":[58],"affected":[60],"subsystems":[62],"(respiratory,":[63],"coagulation,":[64],"circulatory,":[65],"neurological):":[66],"single-system":[67],"(":[68,73,79,97,104,248,254],"n":[69,74,80,98,105],"=":[70,75,81,99,106,176,256],"37),":[71],"dual-system":[72],"62),":[76],"multi-system":[78,152],"8).":[82],"further":[84,130],"compared":[85],"largest":[87],"subgroups":[88],"scores":[92,171],"2\u2014isolated":[94],"respiratory":[95,180,287,321,352],"29)":[100],"versus":[101],"respiratory-coagulation":[102],"59).":[107],"Multivariable":[108],"logistic":[109],"regression":[110],"identified":[111],"predictors":[112],"prolonged":[114,184,230,329],"(\u226510":[117],"days),":[118],"association":[121],"between":[122],"IMV":[123,274,281],"was":[129,224,268],"explored.":[131],"Results":[132],"Respiratory":[133],"and/or":[134],"coagulation":[135],"accounted":[137],"for":[138,229,240,338,348],"89.7%":[139],"(96/107)":[140],"cases,":[142],"respiratory\u2013coagulation":[145],"combination":[146],"being":[147],"most":[148],"frequent":[149],"(55.1%).":[150],"The":[151,341],"group":[153,181,244],"had":[154,182],"highest":[156],"lactate":[159],"levels,":[160],"mortality":[162],"(37.5%,":[163],"all":[164],"P":[165,175,195,204,219,236,249,255],"<":[166,196,205,220,237,250],"0.05).":[167],"Despite":[168],"[2":[172],"(2,":[173],"2),":[174],"0.457],":[177],"isolated":[179],"significantly":[183],"[10":[187],"(9,":[188],"12)":[189],"vs.":[190,202,214],"6":[191],"(4,":[192,212],"8)":[193],"days,":[194,218],"0.001],":[197],"higher":[198,273],"ventilation":[199,209,223,241],"rates":[200],"(100%":[201],"25.4%,":[203],"0.001),":[206],"longer":[208],"duration":[210],"[6":[211],"7)":[213],"0":[215],"(0,":[216],"0)":[217],"0.001].":[221],"Invasive":[222],"strongest":[226],"risk":[227,327],"factor":[228],"(OR=18.80,":[232],"95%":[233],"CI:":[234],"3.78\u2013123.24,":[235],"0.001).":[238],"Adjusting":[239],"attenuated":[242],"effect":[245],"from":[246],"OR=6.92":[247],"0.001)":[251],"OR=1.27":[253],"0.739),":[257],"suggesting":[258],"that":[259],"subgroup":[261],"difference":[262],"largely":[269,332],"explained":[270,333],"use":[275],"single-respiratory":[278],"group.":[279],"Since":[280],"is":[282,346],"part":[283],"subscore,":[288],"this":[289],"attenuation":[290],"likely":[291],"reflects":[292],"shared":[293],"information":[294,357],"rather":[295],"than":[296],"formal":[297],"mediation.":[298],"Conclusions":[299],"In":[300],"septic":[301],"same":[305],"score,":[308],"system":[310],"yield":[313],"substantially":[314],"outcomes":[316],"resource":[318,349],"use.":[319],"A":[320],"score":[323,344],"\u22652":[324],"signals":[325],"high":[326],"stay,":[331],"greater":[336],"need":[337],"invasive":[339],"ventilation.":[340],"alone":[345],"insufficient":[347],"planning;":[350],"component":[353],"may":[354],"provide":[355],"additional":[356],"beyond":[358],"score.":[361]},"counts_by_year":[],"updated_date":"2026-11-09T13:22:03.289127","created_date":"2026-10-22T00:00:00"}