{"id":"https://openalex.org/W7223134013","doi":"https://doi.org/10.1016/j.htct.2026.107291","title":"FREQU\u00caNCIA DE ANTICORPOS IRREGULARES EM PACIENTES ATENDIDOS PELA AG\u00caNCIA TRANSFUSIONAL DO HOSPITAL UNIVERSIT\u00c1RIO OSWALDO CRUZ \u2013 RECIFE-PE, EM 2025","display_name":"FREQU\u00caNCIA DE ANTICORPOS IRREGULARES EM PACIENTES ATENDIDOS PELA AG\u00caNCIA TRANSFUSIONAL DO HOSPITAL UNIVERSIT\u00c1RIO OSWALDO CRUZ \u2013 RECIFE-PE, EM 2025","publication_year":2026,"publication_date":"2026-10-01","ids":{"openalex":"https://openalex.org/W7223134013","doi":"https://doi.org/10.1016/j.htct.2026.107291"},"language":"en","primary_location":{"id":"doi:10.1016/j.htct.2026.107291","doi":"https://doi.org/10.1016/j.htct.2026.107291","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.htct.2026.107291","pdf_url":"https://www.sciencedirect.com/science/article/pii/S2531137926010382/pdf","source":{"id":"https://openalex.org/S2898598332","display_name":"Hematology Transfusion and Cell Therapy","issn_l":"2531-1379","issn":["2531-1379","2531-1387"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","ki-jl-1","poland-20","russia-white-list-3","scielo"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Hematology, Transfusion and Cell Therapy","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj"],"open_access":{"is_oa":true,"oa_status":"diamond","oa_url":"https://www.sciencedirect.com/science/article/pii/S2531137926010382/pdf","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5130713313","display_name":"VANESSA R\u00c9GIA FRANCISCO COUTO COELHO","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210119912","display_name":"Hospital Universit\u00e1rio Oswaldo Cruz","ror":"https://ror.org/02b082946","country_code":"BR","type":"healthcare","lineage":["https://openalex.org/I4210119912"]},{"id":"https://openalex.org/I71437568","display_name":"Universidade de Pernambuco","ror":"https://ror.org/00gtcbp88","country_code":"BR","type":"education","lineage":["https://openalex.org/I71437568"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Vanessa R\u00e9gia Francisco Couto COELHO","raw_affiliation_strings":["Hospital Universit\u00e1rio Oswaldo Cruz (HUOC), Universidade de Pernambuco (UPE), Recife, PE, Brasil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Hospital Universit\u00e1rio Oswaldo Cruz (HUOC), Universidade de Pernambuco (UPE), Recife, PE, Brasil","institution_ids":["https://openalex.org/I4210119912","https://openalex.org/I71437568"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5159219798","display_name":"Maira Judith Azevedo CALLOU","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210119912","display_name":"Hospital Universit\u00e1rio Oswaldo Cruz","ror":"https://ror.org/02b082946","country_code":"BR","type":"healthcare","lineage":["https://openalex.org/I4210119912"]},{"id":"https://openalex.org/I71437568","display_name":"Universidade de Pernambuco","ror":"https://ror.org/00gtcbp88","country_code":"BR","type":"education","lineage":["https://openalex.org/I71437568"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Maira Judith Azevedo CALLOU","raw_affiliation_strings":["Hospital Universit\u00e1rio Oswaldo Cruz (HUOC), Universidade de Pernambuco (UPE), Recife, PE, Brasil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Hospital Universit\u00e1rio Oswaldo Cruz (HUOC), Universidade de Pernambuco (UPE), Recife, PE, Brasil","institution_ids":["https://openalex.org/I4210119912","https://openalex.org/I71437568"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5122654861","display_name":"Franz de Assis Graciano dos SANTOS","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210119912","display_name":"Hospital Universit\u00e1rio Oswaldo Cruz","ror":"https://ror.org/02b082946","country_code":"BR","type":"healthcare","lineage":["https://openalex.org/I4210119912"]},{"id":"https://openalex.org/I71437568","display_name":"Universidade de Pernambuco","ror":"https://ror.org/00gtcbp88","country_code":"BR","type":"education","lineage":["https://openalex.org/I71437568"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Franz De Assis Graciano dos SANTOS","raw_affiliation_strings":["Hospital Universit\u00e1rio Oswaldo Cruz (HUOC), Universidade de Pernambuco (UPE), Recife, PE, Brasil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Hospital Universit\u00e1rio Oswaldo Cruz (HUOC), Universidade de Pernambuco (UPE), Recife, PE, Brasil","institution_ids":["https://openalex.org/I4210119912","https://openalex.org/I71437568"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5159190305","display_name":"Maria do Desterro Fernandes DA SILVA","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210119912","display_name":"Hospital Universit\u00e1rio Oswaldo Cruz","ror":"https://ror.org/02b082946","country_code":"BR","type":"healthcare","lineage":["https://openalex.org/I4210119912"]},{"id":"https://openalex.org/I71437568","display_name":"Universidade de Pernambuco","ror":"https://ror.org/00gtcbp88","country_code":"BR","type":"education","lineage":["https://openalex.org/I71437568"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Maria Virginia da SILVA","raw_affiliation_strings":["Hospital Universit\u00e1rio Oswaldo Cruz (HUOC), Universidade de Pernambuco (UPE), Recife, PE, Brasil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Hospital Universit\u00e1rio Oswaldo Cruz (HUOC), Universidade de Pernambuco (UPE), Recife, PE, Brasil","institution_ids":["https://openalex.org/I4210119912","https://openalex.org/I71437568"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5159204503","display_name":"Patricia De Menezes ARA\u00faJO","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210119912","display_name":"Hospital Universit\u00e1rio Oswaldo Cruz","ror":"https://ror.org/02b082946","country_code":"BR","type":"healthcare","lineage":["https://openalex.org/I4210119912"]},{"id":"https://openalex.org/I71437568","display_name":"Universidade de Pernambuco","ror":"https://ror.org/00gtcbp88","country_code":"BR","type":"education","lineage":["https://openalex.org/I71437568"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Patr\u00edcia De Menezes ARA\u00daJO","raw_affiliation_strings":["Hospital Universit\u00e1rio Oswaldo Cruz (HUOC), Universidade de Pernambuco (UPE), Recife, PE, Brasil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Hospital Universit\u00e1rio Oswaldo Cruz (HUOC), Universidade de Pernambuco (UPE), Recife, PE, Brasil","institution_ids":["https://openalex.org/I4210119912","https://openalex.org/I71437568"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":0,"currency":"USD","value_usd":0},"apc_paid":null,"fwci":0.0,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":{"value":0.79413615,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"48","issue":null,"first_page":"107291","last_page":"107291"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11660","display_name":"Blood groups and transfusion","score":0.9926999807357788,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11660","display_name":"Blood groups and transfusion","score":0.9926999807357788,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10693","display_name":"Blood transfusion and management","score":0.005200000014156103,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12735","display_name":"Blood donation and transfusion practices","score":0.0003000000142492354,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/irregular-antibodies","display_name":"irregular antibodies","score":0.9610000252723694},{"id":"https://openalex.org/keywords/antibody-screening","display_name":"antibody screening","score":0.7080000042915344},{"id":"https://openalex.org/keywords/transfusion-safety","display_name":"transfusion safety","score":0.6769999861717224},{"id":"https://openalex.org/keywords/alloimmunization","display_name":"alloimmunization","score":0.8479999899864197},{"id":"https://openalex.org/keywords/anti-e","display_name":"anti-E","score":0.6010000109672546},{"id":"https://openalex.org/keywords/anti-d","display_name":"anti-D","score":0.9789999723434448},{"id":"https://openalex.org/keywords/anti-c-antibody","display_name":"anti-C antibody","score":0.8849999904632568},{"id":"https://openalex.org/keywords/rh-blood-group-system","display_name":"Rh blood group system","score":0.5460000038146973},{"id":"https://openalex.org/keywords/abo-blood-group","display_name":"ABO blood group system","score":0.6019999980926514},{"id":"https://openalex.org/keywords/anti-hla-antibodies","display_name":"HLA antibodies","score":0.40400001406669617},{"id":"https://openalex.org/keywords/hla-g","display_name":"HLA-G","score":0.30399999022483826},{"id":"https://openalex.org/keywords/hla-e","display_name":"HLA-E","score":0.4189999997615814},{"id":"https://openalex.org/keywords/hla-a","display_name":"HLA-A","score":0.4620000123977661},{"id":"https://openalex.org/keywords/hla-b","display_name":"HLA-B","score":0.6460000276565552},{"id":"https://openalex.org/keywords/hla-dr","display_name":"HLA-DR","score":0.5550000071525574},{"id":"https://openalex.org/keywords/hla-dq","display_name":"HLA-DQ","score":0.7760000228881836},{"id":"https://openalex.org/keywords/hla-dp","display_name":"HLA-DP","score":0.8270000219345093},{"id":"https://openalex.org/keywords/hla-drb1","display_name":"HLA-DRB1","score":0.47200000286102295},{"id":"https://openalex.org/keywords/hla-dqb1","display_name":"HLA-DQB1","score":0.6890000104904175},{"id":"https://openalex.org/keywords/hla-dpb1","display_name":"HLA-DPB1","score":0.6589999794960022},{"id":"https://openalex.org/keywords/hla-drb3","display_name":"HLA-DRB3","score":0.6449999809265137},{"id":"https://openalex.org/keywords/hla-drb4","display_name":"HLA-DRB4","score":0.8330000042915344},{"id":"https://openalex.org/keywords/hla-drb5","display_name":"HLA-DRB5","score":0.9240000247955322},{"id":"https://openalex.org/keywords/hla-dqb2","display_name":"HLA-DQB2","score":0.6480000019073486},{"id":"https://openalex.org/keywords/hla-dpb2","display_name":"HLA-DPB2","score":0.7379999756813049},{"id":"https://openalex.org/keywords/hla-drb1-03","display_name":"HLA-DRB1*03","score":0.5709999799728394}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9585999846458435},{"id":"https://openalex.org/C29456083","wikidata":"https://www.wikidata.org/wiki/Q1221899","display_name":"Gynecology","level":1,"score":0.335099995136261},{"id":"https://openalex.org/C187212893","wikidata":"https://www.wikidata.org/wiki/Q123028","display_name":"Pediatrics","level":1,"score":0.28850001096725464},{"id":"https://openalex.org/C2779473830","wikidata":"https://www.wikidata.org/wiki/Q1540899","display_name":"MEDLINE","level":2,"score":0.25099998712539673},{"id":"https://openalex.org/C3006700255","wikidata":"https://www.wikidata.org/wiki/Q81068910","display_name":"2019-20 coronavirus outbreak","level":3,"score":0.22509999573230743},{"id":"https://openalex.org/C3007834351","wikidata":"https://www.wikidata.org/wiki/Q82069695","display_name":"Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)","level":5,"score":0.21580000221729279},{"id":"https://openalex.org/C177713679","wikidata":"https://www.wikidata.org/wiki/Q679690","display_name":"Intensive care medicine","level":1,"score":0.19529999792575836},{"id":"https://openalex.org/C545542383","wikidata":"https://www.wikidata.org/wiki/Q2751242","display_name":"Medical emergency","level":1,"score":0.193900004029274},{"id":"https://openalex.org/C3008058167","wikidata":"https://www.wikidata.org/wiki/Q84263196","display_name":"Coronavirus disease 2019 (COVID-19)","level":4,"score":0.19120000302791595},{"id":"https://openalex.org/C159047783","wikidata":"https://www.wikidata.org/wiki/Q7215","display_name":"Virology","level":1,"score":0.17579999566078186}],"mesh":[],"locations_count":2,"locations":[{"id":"doi:10.1016/j.htct.2026.107291","doi":"https://doi.org/10.1016/j.htct.2026.107291","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.htct.2026.107291","pdf_url":"https://www.sciencedirect.com/science/article/pii/S2531137926010382/pdf","source":{"id":"https://openalex.org/S2898598332","display_name":"Hematology Transfusion and Cell Therapy","issn_l":"2531-1379","issn":["2531-1379","2531-1387"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","ki-jl-1","poland-20","russia-white-list-3","scielo"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Hematology, Transfusion and Cell Therapy","raw_type":"journal-article"},{"id":"pmh:oai:doaj.org/article:1a0049a5ce5944738243089488fb2915","doi":null,"is_oa":false,"landing_page_url":"https://doaj.org/article/1a0049a5ce5944738243089488fb2915","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Hematology, Transfusion and Cell Therapy, Vol 48, Iss , Pp 107291- (2026)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.1016/j.htct.2026.107291","doi":"https://doi.org/10.1016/j.htct.2026.107291","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.htct.2026.107291","pdf_url":"https://www.sciencedirect.com/science/article/pii/S2531137926010382/pdf","source":{"id":"https://openalex.org/S2898598332","display_name":"Hematology Transfusion and Cell Therapy","issn_l":"2531-1379","issn":["2531-1379","2531-1387"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","ki-jl-1","poland-20","russia-white-list-3","scielo"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Hematology, Transfusion and Cell Therapy","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":1.0,"display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W7223134013.pdf","grobid_xml":"https://content.openalex.org/works/W7223134013.grobid-xml"},"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W7223550831","https://openalex.org/W4387747960","https://openalex.org/W4415669318","https://openalex.org/W4403568159","https://openalex.org/W7223101216","https://openalex.org/W7223090729","https://openalex.org/W7223577015","https://openalex.org/W3106778275","https://openalex.org/W7223152751","https://openalex.org/W4415669911"],"abstract_inverted_index":{"Introdu\u00e7\u00e3o":[0],"A":[1,67,174,318,353,376],"seguran\u00e7a":[2],"transfusional":[3],"depende":[4],"da":[5,61,152,369,373,414,456,461],"triagem":[6],"imuno-hematol\u00f3gica,":[7],"que":[8],"inclui":[9],"a":[10,51,70,78,90,99,144,185,204,212,225,233,240,249,324,358,367,402,411,454],"Pesquisa":[11],"de":[12,20,22,26,29,53,64,72,80,92,121,142,146,182,187,258,312,320,326,333,344,355,360,378,404,423,431,441,443],"Anticorpos":[13],"Irregulares":[14],"(PAI)":[15],"no":[16,189,416],"soro":[17],"ou":[18,111,166],"plasma":[19],"receptores":[21,343],"hemocomponentes.":[23],"No":[24,206,243,265],"\u00e2mbito":[25],"um":[27,57],"hospital":[28,332],"grande":[30],"porte":[31],"e":[32,40,83,97,101,124,128,172,219,237,260,286,293,305,341,347,357,363,372,400,438,458],"refer\u00eancia":[33],"para":[34,463],"transplantes":[35],"hep\u00e1ticos,":[36],"doen\u00e7as":[37,339],"hematol\u00f3gicas,":[38],"oncol\u00f3gicas":[39],"alta":[41,334],"demanda":[42,351],"cir\u00fargica,":[43],"como":[44],"o":[45,84,102,119,209,222,231,238,246,261],"Hospital":[46],"Universit\u00e1rio":[47],"Oswaldo":[48],"Cruz":[49],"(HUOC),":[50],"presen\u00e7a":[52,325],"anticorpos":[54,105,177,268,361,379,432,442],"irregulares":[55],"representa":[56],"desafio":[58],"em":[59,270,328],"raz\u00e3o":[60],"necessidade":[62],"recorrente":[63],"suporte":[65],"transfusional.":[66,375],"aloimuniza\u00e7\u00e3o":[68,327],"dificulta":[69],"obten\u00e7\u00e3o":[71],"hemocomponentes":[73],"compat\u00edveis,":[74],"tornando":[75],"relevante":[76],"conhecer":[77],"frequ\u00eancia":[79,91,100,214,319],"PAI":[81,96,153,321,415,427,462],"positiva":[82,322],"perfil":[85,103,467],"dos":[86,104,133,176,469],"anticorpos.":[87],"Objetivo":[88],"Analisar":[89],"resultados":[93,151],"positivos":[94],"na":[95,392],"caracterizar":[98],"identificados,":[106],"considerando":[107],"sua":[108],"ocorr\u00eancia":[109,164,359],"isolada":[110,165],"associada,":[112],"nos":[113,131],"pacientes":[114,337,348,470],"atendidos":[115],"pelo":[116],"HUOC":[117],"durante":[118],"ano":[120],"2025.":[122,147],"Materiais":[123],"m\u00e9todos":[125],"Estudo":[126],"descritivo":[127],"retrospectivo,":[129],"baseado":[130],"registros":[132],"exames":[134],"pr\u00e9-transfusionais":[135],"realizados":[136],"pela":[137,388],"Ag\u00eancia":[138],"Transfusional":[139],"do":[140,276,281,288,295,380,433,466],"HUOC,":[141],"janeiro":[143],"dezembro":[145],"Foram":[148,168,194,272,299],"analisados":[149],"os":[150,156],"e,":[154],"entre":[155,425],"casos":[157],"positivos,":[158],"as":[159,426],"especificidades":[160,356,395,424],"identificadas":[161],"quanto":[162,449],"\u00e0":[163],"associada.":[167],"calculadas":[169],"frequ\u00eancias":[170],"absoluta":[171],"relativa.":[173],"identifica\u00e7\u00e3o":[175],"foi":[178],"realizada":[179],"por":[180,315,331],"pain\u00e9is":[181],"hem\u00e1cias,":[183],"utilizando":[184],"t\u00e9cnica":[186],"gel/centrifuga\u00e7\u00e3o":[188],"hemocentro":[190],"coordenador":[191],"(HEMOPE).":[192],"Resultados":[193],"realizadas":[195],"6.695":[196],"PAI,":[197],"das":[198],"quais":[199],"51":[200],"foram":[201],"positivas,":[202,428],"correspondendo":[203],"0,76%.":[205],"sistema":[207,244,266,277,282,289,296,381,434],"Rh,":[208,382,435],"Anti-E":[210,437],"apresentou":[211],"maior":[213],"(23,52%),":[215],"sendo":[216],"9,80%":[217],"isolado":[218],"13,72%":[220,250],"associado;":[221,236,254],"Anti-D":[223],"correspondeu":[224,248],"11,76%":[226],"(7,84%":[227,251],"isolado;":[228,252],"5,88%":[229],"associado);":[230],"Anti-C,":[232],"9,80%,":[234],"exclusivamente":[235],"Anti-c,":[239],"1,96%,":[241],"associado.":[242,264],"MNS,":[245],"Anti-M":[247],"1,96%":[253],"3,92%":[255],"com":[256,338,349,429],"efeito":[257],"dose)":[259],"Anti-S,":[262],"5,88%,":[263],"Lewis,":[267],"ocorreram":[269],"7,84%.":[271],"identificados":[273],"ainda":[274],"Anti-Jka":[275],"Kidd":[278],"(7,84%),":[279],"Anti-K":[280],"Kell":[283],"(3,92%),":[284],"Anti-Fya":[285],"Anti-Fyb":[287],"Duffy":[290],"(1,96%":[291],"cada)":[292],"Anti-Dia":[294],"Diego":[297],"(1,96%).":[298],"registradas":[300],"26":[301],"ocorr\u00eancias":[302],"isoladas":[303],"(50,98%)":[304],"28":[306],"associadas":[307],"(54,90%),":[308],"podendo":[309],"haver":[310],"mais":[311],"uma":[313],"especificidade":[314],"paciente.":[316],"Discuss\u00e3o":[317],"evidencia":[323],"popula\u00e7\u00e3o":[329],"assistida":[330],"complexidade,":[335],"incluindo":[336],"hematol\u00f3gicas":[340],"oncol\u00f3gicas,":[342],"transplante":[345],"hep\u00e1tico":[346],"elevada":[350],"cir\u00fargica.":[352],"diversidade":[354,422],"isolados":[362,448],"associados":[364],"podem":[365,396],"aumentar":[366],"complexidade":[368],"investiga\u00e7\u00e3o":[370,398],"imuno-hematol\u00f3gica":[371],"compatibiliza\u00e7\u00e3o":[374],"predomin\u00e2ncia":[377,430],"especialmente":[383,436],"Anti-E,":[384],"apresenta":[385],"relev\u00e2ncia":[386,412],"cl\u00ednica":[387,413],"import\u00e2ncia":[389,455],"desse":[390],"grupo":[391],"aloimuniza\u00e7\u00e3o.":[393],"M\u00faltiplas":[394],"demandar":[397],"detalhada":[399],"dificultar":[401],"disponibiliza\u00e7\u00e3o":[403],"unidades":[405],"compat\u00edveis.":[406],"Conclus\u00e3o":[407],"O":[408,418],"estudo":[409],"demonstra":[410],"HUOC.":[417],"levantamento":[419],"evidenciou":[420],"ampla":[421],"Anti-D,":[439],"al\u00e9m":[440],"diferentes":[444],"sistemas":[445],"eritrocit\u00e1rios,":[446],"tanto":[447],"associados.":[450],"Esses":[451],"achados":[452],"refor\u00e7am":[453],"realiza\u00e7\u00e3o":[457],"caracteriza\u00e7\u00e3o":[459],"adequada":[460],"melhor":[464],"compreens\u00e3o":[465],"imuno-hematol\u00f3gico":[468],"atendidos.":[471]},"counts_by_year":[],"updated_date":"2026-11-08T12:12:28.789561","created_date":"2026-10-22T00:00:00"}