{"id":"https://openalex.org/W7223125282","doi":"https://doi.org/10.12890/2026_007500","title":"Pulmonary sclerosing pneumocytoma may be an under-recognized pulmonary manifestation of the phosphatase and tensin homolog deleted on chromosome 10 (PTEN) hamartoma tumour syndrome","display_name":"Pulmonary sclerosing pneumocytoma may be an under-recognized pulmonary manifestation of the phosphatase and tensin homolog deleted on chromosome 10 (PTEN) hamartoma tumour syndrome","publication_year":2026,"publication_date":"2026-10-21","ids":{"openalex":"https://openalex.org/W7223125282","doi":"https://doi.org/10.12890/2026_007500","pmid":"https://pubmed.ncbi.nlm.nih.gov/43011698","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/13750768"},"language":"en","primary_location":{"id":"doi:10.12890/2026_007500","doi":"https://doi.org/10.12890/2026_007500","is_oa":true,"landing_page_url":"https://doi.org/10.12890/2026_007500","pdf_url":"https://www.ejcrim.com/index.php/EJCRIM/article/download/7500/6048","source":{"id":"https://openalex.org/S2737828108","display_name":"European Journal of Case Reports in Internal Medicine","issn_l":"2284-2594","issn":["2284-2594"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","ki-jl-1","poland-20","vabb-shw"],"host_organization":"https://openalex.org/P4310317697","host_organization_name":"SMC MEDIA SRL","host_organization_lineage":["https://openalex.org/P4310317697"],"host_organization_lineage_names":["SMC MEDIA SRL"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"European Journal of Case Reports in Internal Medicine","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://www.ejcrim.com/index.php/EJCRIM/article/download/7500/6048","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5033531221","display_name":"Arwa Alghamdi","orcid":"https://orcid.org/0000-0001-6879-7165","observed_orcids":["https://orcid.org/0000-0001-6879-7165"]},"institutions":[{"id":"https://openalex.org/I28022161","display_name":"King Saud University","ror":"https://ror.org/02f81g417","country_code":"SA","type":"education","lineage":["https://openalex.org/I28022161"]}],"countries":["SA"],"is_corresponding":false,"raw_author_name":"Arwa Alghamdi","raw_affiliation_strings":["College of Medicine, King Saud University, Riyadh, Saudi Arabia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"College of Medicine, King Saud University, Riyadh, Saudi Arabia","institution_ids":["https://openalex.org/I28022161"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5129206402","display_name":"Amani Alotaibi","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I28022161","display_name":"King Saud University","ror":"https://ror.org/02f81g417","country_code":"SA","type":"education","lineage":["https://openalex.org/I28022161"]}],"countries":["SA"],"is_corresponding":false,"raw_author_name":"Amani Alotaibi","raw_affiliation_strings":["College of Medicine, King Saud University, Riyadh, Saudi Arabia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"College of Medicine, King Saud University, Riyadh, Saudi Arabia","institution_ids":["https://openalex.org/I28022161"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5159165657","display_name":"Ajwan Aljohani","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I28022161","display_name":"King Saud University","ror":"https://ror.org/02f81g417","country_code":"SA","type":"education","lineage":["https://openalex.org/I28022161"]}],"countries":["SA"],"is_corresponding":false,"raw_author_name":"Ajwan Aljohani","raw_affiliation_strings":["College of Medicine, King Saud University, Riyadh, Saudi Arabia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"College of Medicine, King Saud University, Riyadh, Saudi Arabia","institution_ids":["https://openalex.org/I28022161"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5159184330","display_name":"Adel Almaymuni","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210105508","display_name":"King Fahd Armed Forces Hospital","ror":"https://ror.org/00z1vyk43","country_code":"SA","type":"healthcare","lineage":["https://openalex.org/I4210105508"]}],"countries":["SA"],"is_corresponding":false,"raw_author_name":"Adel Almaymuni","raw_affiliation_strings":["Department of Surgery (Thoracic Surgery Division), King Fahad Armed Forces Hospital, Jeddah, Saudi Arabia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Surgery (Thoracic Surgery Division), King Fahad Armed Forces Hospital, Jeddah, Saudi Arabia","institution_ids":["https://openalex.org/I4210105508"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5081045522","display_name":"Wajd Althakfi","orcid":"https://orcid.org/0000-0002-6221-3672","observed_orcids":["https://orcid.org/0000-0002-6221-3672"]},"institutions":[{"id":"https://openalex.org/I28022161","display_name":"King Saud University","ror":"https://ror.org/02f81g417","country_code":"SA","type":"education","lineage":["https://openalex.org/I28022161"]}],"countries":["SA"],"is_corresponding":false,"raw_author_name":"Wajd Althakfi","raw_affiliation_strings":["Department of Pathology (Histopathology Division), College of Medicine, King Saud University, Riyadh, Saudi Arabia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pathology (Histopathology Division), College of Medicine, King Saud University, Riyadh, Saudi Arabia","institution_ids":["https://openalex.org/I28022161"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5073513178","display_name":"Waseem  M Hajjar","orcid":"https://orcid.org/0000-0001-7916-972X","observed_orcids":["https://orcid.org/0000-0001-7916-972X"]},"institutions":[{"id":"https://openalex.org/I28022161","display_name":"King Saud University","ror":"https://ror.org/02f81g417","country_code":"SA","type":"education","lineage":["https://openalex.org/I28022161"]}],"countries":["SA"],"is_corresponding":true,"raw_author_name":"Waseem M. Hajjar","raw_affiliation_strings":["Department of Surgery (Thoracic Surgery Division), College of Medicine, King Saud University, Riyadh, Saudi Arabia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Surgery (Thoracic Surgery Division), College of Medicine, King Saud University, Riyadh, Saudi Arabia","institution_ids":["https://openalex.org/I28022161"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5073513178"],"corresponding_institution_ids":["https://openalex.org/I28022161"],"apc_list":{"value":300,"currency":"EUR","value_usd":323},"apc_paid":{"value":300,"currency":"EUR","value_usd":323},"fwci":0.0,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":{"value":0.0,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"13","issue":"11","first_page":"007500","last_page":"007500"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T13759","display_name":"Medical Imaging and Pathology Studies","score":0.9907000064849854,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T13759","display_name":"Medical Imaging and Pathology Studies","score":0.9907000064849854,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12049","display_name":"Tuberous Sclerosis Complex Research","score":0.00430000014603138,"subfield":{"id":"https://openalex.org/subfields/2716","display_name":"Genetics (clinical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11586","display_name":"Congenital Diaphragmatic Hernia Studies","score":0.0010000000474974513,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/pulmonary-sclerosing-pneumocytoma","display_name":"pulmonary sclerosing pneumocytoma","score":1.0},{"id":"https://openalex.org/keywords/pten-hamartoma-tumor-syndrome","display_name":"PTEN hamartoma tumor syndrome","score":0.9900000095367432},{"id":"https://openalex.org/keywords/pi3k-akt-mtor-pathway","display_name":"PI3K/AKT/mTOR pathway","score":0.9010000228881836},{"id":"https://openalex.org/keywords/akt1-mutation","display_name":"AKT1 mutation","score":0.8090000152587891},{"id":"https://openalex.org/keywords/pulmonary-nodules","display_name":"pulmonary nodules","score":0.9240000247955322},{"id":"https://openalex.org/keywords/hereditary-cancer-susceptibility","display_name":"hereditary cancer predisposition","score":0.3799999952316284}],"concepts":[{"id":"https://openalex.org/C2777609662","wikidata":"https://www.wikidata.org/wiki/Q416356","display_name":"PTEN","level":4,"score":0.8828999996185303},{"id":"https://openalex.org/C2779549131","wikidata":"https://www.wikidata.org/wiki/Q83167294","display_name":"Tensin","level":5,"score":0.8658999800682068},{"id":"https://openalex.org/C109825262","wikidata":"https://www.wikidata.org/wiki/Q1139164","display_name":"Germline","level":3,"score":0.6718999743461609},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.6025000214576721},{"id":"https://openalex.org/C13514818","wikidata":"https://www.wikidata.org/wiki/Q5552256","display_name":"Germline mutation","level":4,"score":0.6004999876022339},{"id":"https://openalex.org/C2780846426","wikidata":"https://www.wikidata.org/wiki/Q1138188","display_name":"Cowden syndrome","level":5,"score":0.5791000127792358},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.5306000113487244},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.5105000138282776},{"id":"https://openalex.org/C2775932916","wikidata":"https://www.wikidata.org/wiki/Q525075","display_name":"Hamartoma","level":2,"score":0.4934000074863434},{"id":"https://openalex.org/C124224327","wikidata":"https://www.wikidata.org/wiki/Q21120164","display_name":"PAX8","level":4,"score":0.42750000953674316},{"id":"https://openalex.org/C154137905","wikidata":"https://www.wikidata.org/wiki/Q17816452","display_name":"AKT1","level":4,"score":0.39570000767707825},{"id":"https://openalex.org/C37846818","wikidata":"https://www.wikidata.org/wiki/Q18032813","display_name":"BAP1","level":3,"score":0.39070001244544983},{"id":"https://openalex.org/C544855455","wikidata":"https://www.wikidata.org/wiki/Q1070952","display_name":"Histopathology","level":2,"score":0.3901999890804291},{"id":"https://openalex.org/C204232928","wikidata":"https://www.wikidata.org/wiki/Q899285","display_name":"Immunohistochemistry","level":2,"score":0.37720000743865967},{"id":"https://openalex.org/C138626823","wikidata":"https://www.wikidata.org/wiki/Q916504","display_name":"Chromosomal translocation","level":3,"score":0.35670000314712524},{"id":"https://openalex.org/C30481170","wikidata":"https://www.wikidata.org/wiki/Q37748","display_name":"Chromosome","level":3,"score":0.3481000065803528},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.33709999918937683},{"id":"https://openalex.org/C526584372","wikidata":"https://www.wikidata.org/wiki/Q16399","display_name":"Thyroid","level":2,"score":0.33379998803138733},{"id":"https://openalex.org/C134305767","wikidata":"https://www.wikidata.org/wiki/Q725508","display_name":"Somatic cell","level":3,"score":0.31130000948905945},{"id":"https://openalex.org/C2778264664","wikidata":"https://www.wikidata.org/wiki/Q422445","display_name":"Tumor suppressor gene","level":4,"score":0.303600013256073},{"id":"https://openalex.org/C2780942790","wikidata":"https://www.wikidata.org/wiki/Q372016","display_name":"Pathogenesis","level":2,"score":0.2921999990940094},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.28630000352859497},{"id":"https://openalex.org/C153209595","wikidata":"https://www.wikidata.org/wiki/Q501128","display_name":"Single-nucleotide polymorphism","level":4,"score":0.28540000319480896},{"id":"https://openalex.org/C2776731575","wikidata":"https://www.wikidata.org/wiki/Q2916245","display_name":"Nodule (geology)","level":2,"score":0.28529998660087585},{"id":"https://openalex.org/C109748351","wikidata":"https://www.wikidata.org/wiki/Q657319","display_name":"Chromosome 7 (human)","level":4,"score":0.2827000021934509},{"id":"https://openalex.org/C186836561","wikidata":"https://www.wikidata.org/wiki/Q1931516","display_name":"Microarray","level":4,"score":0.27140000462532043},{"id":"https://openalex.org/C530470458","wikidata":"https://www.wikidata.org/wiki/Q128581","display_name":"Breast cancer","level":3,"score":0.2702000141143799},{"id":"https://openalex.org/C2776192174","wikidata":"https://www.wikidata.org/wiki/Q18028978","display_name":"Mdm2","level":3,"score":0.2685000002384186},{"id":"https://openalex.org/C2780238508","wikidata":"https://www.wikidata.org/wiki/Q840604","display_name":"Chromosome 9","level":4,"score":0.267300009727478},{"id":"https://openalex.org/C2777277851","wikidata":"https://www.wikidata.org/wiki/Q1348398","display_name":"Cancer syndrome","level":5,"score":0.2540999948978424},{"id":"https://openalex.org/C2779761222","wikidata":"https://www.wikidata.org/wiki/Q826522","display_name":"Thyroid cancer","level":3,"score":0.2535000145435333},{"id":"https://openalex.org/C35158069","wikidata":"https://www.wikidata.org/wiki/Q61333","display_name":"X chromosome","level":3,"score":0.2515999972820282}],"mesh":[],"locations_count":3,"locations":[{"id":"doi:10.12890/2026_007500","doi":"https://doi.org/10.12890/2026_007500","is_oa":true,"landing_page_url":"https://doi.org/10.12890/2026_007500","pdf_url":"https://www.ejcrim.com/index.php/EJCRIM/article/download/7500/6048","source":{"id":"https://openalex.org/S2737828108","display_name":"European Journal of Case Reports in Internal Medicine","issn_l":"2284-2594","issn":["2284-2594"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","ki-jl-1","poland-20","vabb-shw"],"host_organization":"https://openalex.org/P4310317697","host_organization_name":"SMC MEDIA SRL","host_organization_lineage":["https://openalex.org/P4310317697"],"host_organization_lineage_names":["SMC MEDIA SRL"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"European Journal of Case Reports in Internal Medicine","raw_type":"journal-article"},{"id":"pmid:43011698","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/43011698","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"European journal of case reports in internal medicine","raw_type":"Journal Article"},{"id":"pmh:oai:doaj.org/article:94a1f880a2594ef2815e5fae12dfbe6c","doi":null,"is_oa":false,"landing_page_url":"https://doaj.org/article/94a1f880a2594ef2815e5fae12dfbe6c","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"European Journal of Case Reports in Internal Medicine, Vol 13, Iss 11 (2026)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.12890/2026_007500","doi":"https://doi.org/10.12890/2026_007500","is_oa":true,"landing_page_url":"https://doi.org/10.12890/2026_007500","pdf_url":"https://www.ejcrim.com/index.php/EJCRIM/article/download/7500/6048","source":{"id":"https://openalex.org/S2737828108","display_name":"European Journal of Case Reports in Internal Medicine","issn_l":"2284-2594","issn":["2284-2594"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","ki-jl-1","poland-20","vabb-shw"],"host_organization":"https://openalex.org/P4310317697","host_organization_name":"SMC MEDIA SRL","host_organization_lineage":["https://openalex.org/P4310317697"],"host_organization_lineage_names":["SMC MEDIA SRL"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"European Journal of Case Reports in Internal Medicine","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.9922999739646912}],"study_designs":[{"display_name":"Case Report","id":"https://openalex.org/study-designs/case-report"}],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W7223125282.pdf","grobid_xml":"https://content.openalex.org/works/W7223125282.grobid-xml"},"referenced_works_count":10,"referenced_works":["https://openalex.org/W2010288342","https://openalex.org/W2014322780","https://openalex.org/W2120530835","https://openalex.org/W2948270481","https://openalex.org/W2973601147","https://openalex.org/W3173627210","https://openalex.org/W3175627534","https://openalex.org/W3195679464","https://openalex.org/W4225164723","https://openalex.org/W4387642903"],"related_works":["https://openalex.org/W2948270481","https://openalex.org/W4403807315","https://openalex.org/W3197736369","https://openalex.org/W2772014449","https://openalex.org/W3170526645","https://openalex.org/W7117718333","https://openalex.org/W4311572535","https://openalex.org/W3095356646","https://openalex.org/W2010288342","https://openalex.org/W4416121812"],"abstract_inverted_index":{"Introduction:":[0],"Pulmonary":[1,195],"sclerosing":[2,196],"pneumocytoma":[3,197],"(PSP)":[4,198],"is":[5,51],"a":[6,58,65,92,99,110,116,139,178,186,239,243],"rare,":[7],"benign":[8,89],"neoplasm":[9],"driven":[10],"by":[11,181,227],"somatic":[12],"AKT1":[13],"mutations":[14],"that":[15],"activate":[16],"the":[17,39,46,148,161,231],"PI3K/AKT/mTOR":[18,182,232],"pathway.":[19,48],"Phosphatase":[20],"and":[21,98,115,131,177,207,222],"tensin":[22,208],"homolog":[23,209],"deleted":[24,210],"on":[25,211],"chromosome":[26,212],"10":[27,213],"(PTEN)":[28,214],"hamartoma":[29,215],"tumour":[30,40,179,216],"syndrome":[31,217],"(PHTS)":[32],"results":[33],"from":[34],"germline":[35,141,174],"pathogenic":[36,140],"variants":[37],"affecting":[38],"suppressor":[41],"gene":[42],"PTEN,":[43,146],"which":[44],"regulates":[45],"same":[47],"Although":[49],"PSP":[50,165,221,237],"not":[52],"an":[53,76,201,253],"established":[54],"manifestation":[55,204],"of":[56,61,150,173,205,230,236,252],"PHTS":[57,223],"small":[59],"number":[60],"reports":[62],"have":[63],"suggested":[64],"possible":[66],"association.":[67],"Case":[68],"description:":[69],"A":[70],"23-year-old":[71],"Saudi":[72],"woman":[73],"presented":[74],"with":[75,112,118,168,242],"incidental":[77],"9":[78],"mm":[79],"pulmonary":[80,203],"nodule":[81,95],"detected":[82],"during":[83],"imaging.":[84],"Her":[85],"history":[86,103,248],"included":[87],"bilateral":[88],"thyroid":[90],"nodules,":[91],"left":[93],"breast":[94,108],"(BI-RADS":[96],"3)":[97],"venolymphatic":[100],"malformation.":[101],"Family":[102],"was":[104,128],"significant":[105],"for":[106,190],"maternal":[107],"cancer,":[109],"sister":[111],"diffuse":[113],"lipomatosis,":[114],"brother":[117],"autism":[119],"spectrum":[120],"disorder.":[121,256],"Video-assisted":[122],"thoracoscopic":[123],"surgery":[124],"(VATS)":[125],"wedge":[126],"resection":[127],"performed;":[129],"histopathology":[130],"immunohistochemistry":[132],"confirmed":[133,157],"PSP.":[134],"Chromosomal":[135],"microarray":[136],"analysis":[137],"revealed":[138],"deletion":[142],"at":[143],"10q23.31":[144],"encompassing":[145],"confirming":[147],"diagnosis":[149],"PHTS.":[151],"Conclusion:":[152],"This":[153],"case":[154],"adds":[155],"molecularly":[156],"adult":[158],"evidence":[159],"to":[160],"limited":[162],"literature":[163],"describing":[164],"in":[166,238],"patients":[167],"PTEN":[169,175],"alterations.":[170],"The":[171],"coexistence":[172],"loss":[176],"characterized":[180],"pathway":[183],"activation":[184],"provides":[185],"biologically":[187],"plausible":[188],"basis":[189],"further":[191],"investigation.":[192],"LEARNING":[193],"POINTS:":[194],"may":[199,224,249],"represent":[200],"under-recognized":[202],"phosphatase":[206],"(PHTS).The":[218],"association":[219],"between":[220],"be":[225],"explained":[226],"shared":[228],"involvement":[229],"signalling":[233],"pathway.The":[234],"presence":[235],"young":[240],"patient":[241],"suggestive":[244],"personal":[245],"or":[246],"family":[247],"warrant":[250],"consideration":[251],"underlying":[254],"PTEN-related":[255]},"counts_by_year":[],"updated_date":"2026-11-12T12:28:57.059296","created_date":"2026-10-22T00:00:00"}