{"id":"https://openalex.org/W7223096837","doi":"https://doi.org/10.1016/j.htct.2026.107823","title":"RESPOSTA COMPLETA COMPAT\u00cdVEL COM EFEITO ABSCOPAL EM LINFOMA FOLICULAR MULTIRREFRAT\u00c1RIO AP\u00d3S RADIOTERAPIA LOCALIZADA: RELATO DE CASO","display_name":"RESPOSTA COMPLETA COMPAT\u00cdVEL COM EFEITO ABSCOPAL EM LINFOMA FOLICULAR MULTIRREFRAT\u00c1RIO AP\u00d3S RADIOTERAPIA LOCALIZADA: RELATO DE CASO","publication_year":2026,"publication_date":"2026-10-01","ids":{"openalex":"https://openalex.org/W7223096837","doi":"https://doi.org/10.1016/j.htct.2026.107823"},"language":"en","primary_location":{"id":"doi:10.1016/j.htct.2026.107823","doi":"https://doi.org/10.1016/j.htct.2026.107823","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.htct.2026.107823","pdf_url":"https://www.sciencedirect.com/science/article/pii/S2531137926015701/pdf","source":{"id":"https://openalex.org/S2898598332","display_name":"Hematology Transfusion and Cell Therapy","issn_l":"2531-1379","issn":["2531-1379","2531-1387"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","ki-jl-1","poland-20","russia-white-list-3","scielo"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Hematology, Transfusion and Cell Therapy","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj"],"open_access":{"is_oa":true,"oa_status":"diamond","oa_url":"https://www.sciencedirect.com/science/article/pii/S2531137926015701/pdf","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5159203693","display_name":"Yuri Zammar JORGE","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210117182","display_name":"Hospital Universit\u00e1rio Evang\u00e9lico de Curitiba","ror":"https://ror.org/022yckc24","country_code":"BR","type":"healthcare","lineage":["https://openalex.org/I4210117182"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Yuri Zammar JORGE","raw_affiliation_strings":["Hospital Universit\u00e1rio Evang\u00e9lico Mackenzie, Curitiba, PR, Brasi"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Hospital Universit\u00e1rio Evang\u00e9lico Mackenzie, Curitiba, PR, Brasi","institution_ids":["https://openalex.org/I4210117182"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5003000440","display_name":"Fabiola Pabst BREMER","orcid":"https://orcid.org/0000-0002-6817-8409","observed_orcids":["https://orcid.org/0000-0002-6817-8409"]},"institutions":[{"id":"https://openalex.org/I4210117182","display_name":"Hospital Universit\u00e1rio Evang\u00e9lico de Curitiba","ror":"https://ror.org/022yckc24","country_code":"BR","type":"healthcare","lineage":["https://openalex.org/I4210117182"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Fab\u00edola Pabst BREMER","raw_affiliation_strings":["Hospital Universit\u00e1rio Evang\u00e9lico Mackenzie, Curitiba, PR, Brasi"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Hospital Universit\u00e1rio Evang\u00e9lico Mackenzie, Curitiba, PR, Brasi","institution_ids":["https://openalex.org/I4210117182"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5023655470","display_name":"Joelma Pietrovicz","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210117182","display_name":"Hospital Universit\u00e1rio Evang\u00e9lico de Curitiba","ror":"https://ror.org/022yckc24","country_code":"BR","type":"healthcare","lineage":["https://openalex.org/I4210117182"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Joelma PIETROVICZ","raw_affiliation_strings":["Hospital Universit\u00e1rio Evang\u00e9lico Mackenzie, Curitiba, PR, Brasi"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Hospital Universit\u00e1rio Evang\u00e9lico Mackenzie, Curitiba, PR, Brasi","institution_ids":["https://openalex.org/I4210117182"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5093083990","display_name":"Maur\u00edcio LITTIERI","orcid":"https://orcid.org/0000-0002-4442-1339","observed_orcids":["https://orcid.org/0000-0002-4442-1339"]},"institutions":[{"id":"https://openalex.org/I4210117182","display_name":"Hospital Universit\u00e1rio Evang\u00e9lico de Curitiba","ror":"https://ror.org/022yckc24","country_code":"BR","type":"healthcare","lineage":["https://openalex.org/I4210117182"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Maur\u00edcio LITTIERI","raw_affiliation_strings":["Hospital Universit\u00e1rio Evang\u00e9lico Mackenzie, Curitiba, PR, Brasi"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Hospital Universit\u00e1rio Evang\u00e9lico Mackenzie, Curitiba, PR, Brasi","institution_ids":["https://openalex.org/I4210117182"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5159179914","display_name":"Felipe Ricardo de Souza OLIVEIRA","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210117182","display_name":"Hospital Universit\u00e1rio Evang\u00e9lico de Curitiba","ror":"https://ror.org/022yckc24","country_code":"BR","type":"healthcare","lineage":["https://openalex.org/I4210117182"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Felipe Ricardo de Souza OLIVEIRA","raw_affiliation_strings":["Hospital Universit\u00e1rio Evang\u00e9lico Mackenzie, Curitiba, PR, Brasi"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Hospital Universit\u00e1rio Evang\u00e9lico Mackenzie, Curitiba, PR, Brasi","institution_ids":["https://openalex.org/I4210117182"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5159199489","display_name":"Giovanna Mendes de Abreu SILVA","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Giovanna Bortolassi DA SILVA","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5042161231","display_name":"Helena Dos Santos REIS","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210117182","display_name":"Hospital Universit\u00e1rio Evang\u00e9lico de Curitiba","ror":"https://ror.org/022yckc24","country_code":"BR","type":"healthcare","lineage":["https://openalex.org/I4210117182"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Helena dos Santos REIS","raw_affiliation_strings":["Hospital Universit\u00e1rio Evang\u00e9lico Mackenzie, Curitiba, PR, Brasi"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Hospital Universit\u00e1rio Evang\u00e9lico Mackenzie, Curitiba, PR, Brasi","institution_ids":["https://openalex.org/I4210117182"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5159189974","display_name":"Luiza Martins AFFORNALI","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210117182","display_name":"Hospital Universit\u00e1rio Evang\u00e9lico de Curitiba","ror":"https://ror.org/022yckc24","country_code":"BR","type":"healthcare","lineage":["https://openalex.org/I4210117182"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Luiza Martins AFFORNALI","raw_affiliation_strings":["Hospital Universit\u00e1rio Evang\u00e9lico Mackenzie, Curitiba, PR, Brasi"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Hospital Universit\u00e1rio Evang\u00e9lico Mackenzie, Curitiba, PR, Brasi","institution_ids":["https://openalex.org/I4210117182"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5159215576","display_name":"Manuela Romero MACEDO","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210117182","display_name":"Hospital Universit\u00e1rio Evang\u00e9lico de Curitiba","ror":"https://ror.org/022yckc24","country_code":"BR","type":"healthcare","lineage":["https://openalex.org/I4210117182"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Manuela Romero MACEDO","raw_affiliation_strings":["Hospital Universit\u00e1rio Evang\u00e9lico Mackenzie, Curitiba, PR, Brasi"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Hospital Universit\u00e1rio Evang\u00e9lico Mackenzie, Curitiba, PR, Brasi","institution_ids":["https://openalex.org/I4210117182"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5159173061","display_name":"Roberto Hobi Weiss Cunha DE CASTILHO","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Roberto Hobi Weiss Cunha DE CASTILHO","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5031735143","display_name":"Samara Reckziegel","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210117182","display_name":"Hospital Universit\u00e1rio Evang\u00e9lico de Curitiba","ror":"https://ror.org/022yckc24","country_code":"BR","type":"healthcare","lineage":["https://openalex.org/I4210117182"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Samara RECKZIEGEL","raw_affiliation_strings":["Hospital Universit\u00e1rio Evang\u00e9lico Mackenzie, Curitiba, PR, Brasi"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Hospital Universit\u00e1rio Evang\u00e9lico Mackenzie, Curitiba, PR, Brasi","institution_ids":["https://openalex.org/I4210117182"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":0,"currency":"USD","value_usd":0},"apc_paid":null,"fwci":0.0,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":{"value":0.84051765,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"48","issue":null,"first_page":"107823","last_page":"107823"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10185","display_name":"Lymphoma Diagnosis and Treatment","score":0.9961000084877014,"subfield":{"id":"https://openalex.org/subfields/2734","display_name":"Pathology and Forensic Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10185","display_name":"Lymphoma Diagnosis and Treatment","score":0.9961000084877014,"subfield":{"id":"https://openalex.org/subfields/2734","display_name":"Pathology and Forensic Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10685","display_name":"Viral-associated cancers and disorders","score":0.0005000000237487257,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11811","display_name":"Cutaneous lymphoproliferative disorders research","score":0.00039999998989515007,"subfield":{"id":"https://openalex.org/subfields/2708","display_name":"Dermatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/abscopal-effect","display_name":"abscopal effect","score":0.9869999885559082},{"id":"https://openalex.org/keywords/follicular-lymphoma","display_name":"follicular lymphoma","score":0.8759999871253967},{"id":"https://openalex.org/keywords/palliative-radiotherapy","display_name":"palliative radiotherapy","score":0.7649999856948853},{"id":"https://openalex.org/keywords/complete-response","display_name":"complete response","score":0.7580000162124634},{"id":"https://openalex.org/keywords/cd8-t-cells","display_name":"CD8+ T cells","score":0.6930000185966492},{"id":"https://openalex.org/keywords/systemic-immune-response","display_name":"systemic immune response","score":0.6840000152587891},{"id":"https://openalex.org/keywords/immunogenic-cell-death","display_name":"immunogenic cell death","score":0.5839999914169312},{"id":"https://openalex.org/keywords/lymphoma-progression","display_name":"lymphoma progression","score":0.3490000069141388},{"id":"https://openalex.org/keywords/treatment-futility","display_name":"futility of treatment","score":0.3370000123977661},{"id":"https://openalex.org/keywords/r-chop","display_name":"R-CHOP","score":0.5460000038146973},{"id":"https://openalex.org/keywords/salvage-chemotherapy","display_name":"salvage chemotherapy","score":0.3240000009536743},{"id":"https://openalex.org/keywords/lymphadenopathy","display_name":"lymphadenopathy","score":0.3190000057220459},{"id":"https://openalex.org/keywords/subcutaneous-nodules","display_name":"subcutaneous nodules","score":0.7179999947547913},{"id":"https://openalex.org/keywords/brazil","display_name":"Brazil","score":0.3319999873638153}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9599000215530396},{"id":"https://openalex.org/C2781274730","wikidata":"https://www.wikidata.org/wiki/Q4669679","display_name":"Abscopal effect","level":4,"score":0.4196000099182129},{"id":"https://openalex.org/C2989005","wikidata":"https://www.wikidata.org/wiki/Q214963","display_name":"Nuclear medicine","level":1,"score":0.3375999927520752},{"id":"https://openalex.org/C29456083","wikidata":"https://www.wikidata.org/wiki/Q1221899","display_name":"Gynecology","level":1,"score":0.30820000171661377},{"id":"https://openalex.org/C509974204","wikidata":"https://www.wikidata.org/wiki/Q180507","display_name":"Radiation therapy","level":2,"score":0.2409999966621399},{"id":"https://openalex.org/C16005928","wikidata":"https://www.wikidata.org/wiki/Q171171","display_name":"Dermatology","level":1,"score":0.18770000338554382},{"id":"https://openalex.org/C2987700449","wikidata":"https://www.wikidata.org/wiki/Q186161","display_name":"Radiation dose","level":2,"score":0.10459999740123749},{"id":"https://openalex.org/C2993278735","wikidata":"https://www.wikidata.org/wiki/Q275459","display_name":"Radiation injury","level":3,"score":0.08829999715089798},{"id":"https://openalex.org/C187785154","wikidata":"https://www.wikidata.org/wiki/Q5464664","display_name":"Follicular phase","level":2,"score":0.08579999953508377},{"id":"https://openalex.org/C126838900","wikidata":"https://www.wikidata.org/wiki/Q77604","display_name":"Radiology","level":1,"score":0.0851999968290329}],"mesh":[],"locations_count":2,"locations":[{"id":"doi:10.1016/j.htct.2026.107823","doi":"https://doi.org/10.1016/j.htct.2026.107823","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.htct.2026.107823","pdf_url":"https://www.sciencedirect.com/science/article/pii/S2531137926015701/pdf","source":{"id":"https://openalex.org/S2898598332","display_name":"Hematology Transfusion and Cell Therapy","issn_l":"2531-1379","issn":["2531-1379","2531-1387"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","ki-jl-1","poland-20","russia-white-list-3","scielo"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Hematology, Transfusion and Cell Therapy","raw_type":"journal-article"},{"id":"pmh:oai:doaj.org/article:c5c66b4e34f047d9bf437cad552e9f98","doi":null,"is_oa":false,"landing_page_url":"https://doaj.org/article/c5c66b4e34f047d9bf437cad552e9f98","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Hematology, Transfusion and Cell Therapy, Vol 48, Iss , Pp 107823- (2026)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.1016/j.htct.2026.107823","doi":"https://doi.org/10.1016/j.htct.2026.107823","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.htct.2026.107823","pdf_url":"https://www.sciencedirect.com/science/article/pii/S2531137926015701/pdf","source":{"id":"https://openalex.org/S2898598332","display_name":"Hematology Transfusion and Cell Therapy","issn_l":"2531-1379","issn":["2531-1379","2531-1387"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","ki-jl-1","poland-20","russia-white-list-3","scielo"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Hematology, Transfusion and Cell Therapy","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.9763000011444092,"display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/case-report","display_name":"Case Report"}],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W7223096837.pdf","grobid_xml":"https://content.openalex.org/works/W7223096837.grobid-xml"},"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W3202863753","https://openalex.org/W7211892961","https://openalex.org/W2051212887","https://openalex.org/W2110081577","https://openalex.org/W3081898590","https://openalex.org/W2980052686","https://openalex.org/W2989628398","https://openalex.org/W4405070154","https://openalex.org/W7120224780","https://openalex.org/W4415933213"],"abstract_inverted_index":{"Introdu\u00e7\u00e3o":[0],"O":[1,349],"efeito":[2,45,63,281],"abscopal":[3,64,282],"\u00e9":[4],"um":[5,56],"fen\u00f4meno":[6],"raro":[7],"e":[8,34,99,119,152,164,193,290,316],"imunomediado,":[9],"no":[10,139,285],"qual":[11],"a":[12,106,110,124,130,134,184,198,218,228,231,311,326],"radioterapia":[13,29,69,205,238,303,356],"localizada":[14],"induz":[15],"regress\u00e3o":[16,296],"de":[17,58,73,81,113,132,167,189,214,255,292,298,342,363],"les\u00f5es":[18,299],"fora":[19],"do":[20,200,331],"campo":[21],"irradiado,":[22],"descrito":[23,275],"sobretudo":[24],"em":[25,46,65,84,127,136,211,259,269,277,345,361],"tumores":[26,47,278],"s\u00f3lidos.":[27],"A":[28,295],"promove":[30],"morte":[31,323],"celular":[32,324],"imunog\u00eanica":[33],"resposta":[35,59,142,256,264,318],"imune":[36,319],"sist\u00eamica":[37,320],"mediada":[38],"por":[39,87,150,179,287],"linf\u00f3citos":[40,293],"T":[41],"CD8+,":[42],"favorecendo":[43],"o":[44,50,165,248,280,352],"imunog\u00eanicos,":[48],"como":[49,357],"linfoma":[51],"folicular":[52],"(LF).":[53],"Objetivos":[54],"Relatar":[55],"caso":[57,74,346,350],"completa":[60,265],"compat\u00edvel":[61],"com":[62,79,94],"LF":[66,82,286],"multirrefrat\u00e1rio":[67],"ap\u00f3s":[68,302],"paliativa":[70],"isolada.":[71,239],"Relato":[72],"Paciente":[75],"feminina,":[76],"51":[77],"anos,":[78],"diagn\u00f3stico":[80],"cl\u00e1ssico":[83],"2023,":[85],"confirmado":[86],"bi\u00f3psia":[88,156],"excisional":[89],"(padr\u00e3o":[90],"nodular,":[91],"grau":[92,162],"1-2),":[93],"estadiamento":[95],"Ann":[96],"Arbor":[97],"III-A":[98],"FLIPI":[100],"3":[101],"(alto":[102],"risco).":[103],"De":[104],"2023":[105],"2025":[107],"foi":[108],"submetida":[109],"quatro":[111],"linhas":[112,137],"tratamento":[114],"\u2014":[115],"R-CHOP,":[116,145],"DHAP,":[117],"GEMOX":[118],"ICE":[120],"\u2014,":[121],"sendo":[122,202],"somente":[123],"primeira":[125,253],"baseada":[126,344],"quimioimunoterapia,":[128],"dada":[129],"falta":[131],"acesso":[133],"imunoter\u00e1picos":[135],"subsequentes":[138],"SUS.":[140],"Ap\u00f3s":[141],"parcial":[143],"ao":[144,244],"houve":[146,221],"progress\u00e3o":[147,170],"sucessiva":[148],"documentada":[149],"PET":[151,166,249],"tomografia.":[153],"Uma":[154],"segunda":[155],"(janeiro/2025)":[157],"registrou":[158,250],"evolu\u00e7\u00e3o":[159],"histol\u00f3gica":[160],"para":[161,204,368],"3A,":[163],"mar\u00e7o/2025":[168],"evidenciou":[169],"franca":[171],"(Deauville":[172],"5),":[173],"levando":[174],"\u00e0":[175,313,330],"suspens\u00e3o":[176],"da":[177,246,355],"quimioterapia":[178,314],"futilidade":[180],"terap\u00eautica.":[181],"Nesse":[182],"momento,":[183],"paciente":[185],"apresentou":[186],"crescimento":[187],"intenso":[188],"linfonodomegalia":[190],"axilar":[191],"esquerda":[192],"implantes":[194],"nodulares":[195],"subcut\u00e2neos,":[196],"limitando":[197],"movimenta\u00e7\u00e3o":[199],"membro,":[201],"encaminhada":[203],"paliativa,":[206],"que":[207,227],"totalizou":[208],"40,5":[209],"Gy":[210],"15":[212],"fra\u00e7\u00f5es":[213],"270":[215],"cGy":[216],"(abril":[217],"maio/2025).":[219],"N\u00e3o":[220],"imunoterapia":[222,306],"concomitante":[223],"ou":[224],"recente,":[225,307],"visto":[226],"\u00faltima":[229],"exposi\u00e7\u00e3o":[230],"anti-CD20":[232],"ocorreu":[233],"18":[234],"meses":[235],"antes,":[236],"caracterizando":[237],"Em":[240],"junho/2025,":[241],"m\u00eas":[242],"seguinte":[243],"t\u00e9rmino":[245],"radioterapia,":[247],"Deauville":[251,261],"3,":[252],"evid\u00eancia":[254],"completa,":[257],"e,":[258],"dezembro/2025,":[260],"2,":[262],"indicando":[263],"metab\u00f3lica":[266],"sustentada,":[267],"inclusive":[268],"s\u00edtios":[270],"n\u00e3o":[271,300],"irradiados.":[272],"Discuss\u00e3o":[273],"Embora":[274],"majoritariamente":[276],"s\u00f3lidos,":[279],"tem":[283],"plausibilidade":[284],"sua":[288],"imunogenicidade":[289],"depend\u00eancia":[291],"T.":[294],"sustentada":[297],"irradiadas":[301],"isolada,":[304],"sem":[305],"torna":[308],"pouco":[309],"prov\u00e1vel":[310],"atribui\u00e7\u00e3o":[312],"pr\u00e9via":[315],"sugere":[317],"desencadeada":[321],"pela":[322],"imunog\u00eanica;":[325],"dose":[327],"empregada,":[328],"superior":[329],"esquema":[332],"paliativo":[333],"habitual,":[334],"pode":[335],"ter":[336],"ampliado":[337],"esse":[338],"est\u00edmulo.":[339],"Trata-se,":[340],"contudo,":[341],"infer\u00eancia":[343],"\u00fanico.":[347],"Conclus\u00e3o":[348],"refor\u00e7a":[351],"potencial":[353],"imunomodulador":[354],"mecanismo":[358],"relevante":[359],"mesmo":[360],"cen\u00e1rios":[362],"refratariedade,":[364],"justificando":[365],"investiga\u00e7\u00f5es":[366],"prospectivas":[367],"compreender":[369],"seus":[370],"determinantes.":[371]},"counts_by_year":[],"updated_date":"2026-11-08T12:12:28.789561","created_date":"2026-10-22T00:00:00"}