{"id":"https://openalex.org/W7223054536","doi":"https://doi.org/10.3389/fcvm.2026.1903773","title":"Totally endoscopic mitral valve replacement: reasons for non-feasibility of repair and 5-year outcomes","display_name":"Totally endoscopic mitral valve replacement: reasons for non-feasibility of repair and 5-year outcomes","publication_year":2026,"publication_date":"2026-10-20","ids":{"openalex":"https://openalex.org/W7223054536","doi":"https://doi.org/10.3389/fcvm.2026.1903773","pmid":"https://pubmed.ncbi.nlm.nih.gov/42978567","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/13727415"},"language":"en","primary_location":{"id":"doi:10.3389/fcvm.2026.1903773","doi":"https://doi.org/10.3389/fcvm.2026.1903773","is_oa":true,"landing_page_url":"https://doi.org/10.3389/fcvm.2026.1903773","pdf_url":"https://www.frontiersin.org/journals/cardiovascular-medicine/articles/10.3389/fcvm.2026.1903773/pdf","source":{"id":"https://openalex.org/S2595413687","display_name":"Frontiers in Cardiovascular Medicine","issn_l":"2297-055X","issn":["2297-055X"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","jufo-1","ki-jl-1","norway-1","poland-40","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320527","host_organization_name":"Frontiers Media","host_organization_lineage":["https://openalex.org/P4310320527"],"host_organization_lineage_names":["Frontiers Media"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in Cardiovascular Medicine","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://www.frontiersin.org/journals/cardiovascular-medicine/articles/10.3389/fcvm.2026.1903773/pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5086088074","display_name":"Friedrich Sobik","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I159176309","display_name":"Universit\u00e4t Hamburg","ror":"https://ror.org/00g30e956","country_code":"DE","type":"education","lineage":["https://openalex.org/I159176309"]},{"id":"https://openalex.org/I4210108711","display_name":"University Medical Center Hamburg-Eppendorf","ror":"https://ror.org/01zgy1s35","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I159176309","https://openalex.org/I4210108711"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Friedrich Sobik","raw_affiliation_strings":["Department of Cardiac Surgery, University Heart and Vascular Center Hamburg, University Medical Center Hamburg-Eppendorf"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cardiac Surgery, University Heart and Vascular Center Hamburg, University Medical Center Hamburg-Eppendorf","institution_ids":["https://openalex.org/I159176309","https://openalex.org/I4210108711"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5040294055","display_name":"Jonas Pausch","orcid":"https://orcid.org/0000-0002-7418-1815","observed_orcids":["https://orcid.org/0000-0002-7418-1815"]},"institutions":[{"id":"https://openalex.org/I159176309","display_name":"Universit\u00e4t Hamburg","ror":"https://ror.org/00g30e956","country_code":"DE","type":"education","lineage":["https://openalex.org/I159176309"]},{"id":"https://openalex.org/I4210108711","display_name":"University Medical Center Hamburg-Eppendorf","ror":"https://ror.org/01zgy1s35","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I159176309","https://openalex.org/I4210108711"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Jonas Pausch","raw_affiliation_strings":["Department of Cardiac Surgery, University Heart and Vascular Center Hamburg, University Medical Center Hamburg-Eppendorf"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cardiac Surgery, University Heart and Vascular Center Hamburg, University Medical Center Hamburg-Eppendorf","institution_ids":["https://openalex.org/I159176309","https://openalex.org/I4210108711"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112587573","display_name":"Xiaoqin Hua","orcid":"https://orcid.org/0009-0005-1859-6345","observed_orcids":["https://orcid.org/0009-0005-1859-6345"]},"institutions":[{"id":"https://openalex.org/I4210153755","display_name":"University Hospital Cologne","ror":"https://ror.org/05mxhda18","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I4210153755"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Xiaoqin Hua","raw_affiliation_strings":["Department of Cardiac Surgery, University Hospital Cologne"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cardiac Surgery, University Hospital Cologne","institution_ids":["https://openalex.org/I4210153755"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5018424227","display_name":"Martin Beyer","orcid":"https://orcid.org/0000-0003-0925-7067","observed_orcids":["https://orcid.org/0000-0003-0925-7067"]},"institutions":[{"id":"https://openalex.org/I159176309","display_name":"Universit\u00e4t Hamburg","ror":"https://ror.org/00g30e956","country_code":"DE","type":"education","lineage":["https://openalex.org/I159176309"]},{"id":"https://openalex.org/I4210108711","display_name":"University Medical Center Hamburg-Eppendorf","ror":"https://ror.org/01zgy1s35","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I159176309","https://openalex.org/I4210108711"]},{"id":"https://openalex.org/I4210127591","display_name":"German Centre for Cardiovascular Research","ror":"https://ror.org/031t5w623","country_code":"DE","type":"facility","lineage":["https://openalex.org/I4210127591","https://openalex.org/I4405256427"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Martin Beyer","raw_affiliation_strings":["DZHK (German Centre for Cardiovascular Research), Partner Site North","Department of Cardiac Surgery, University Heart and Vascular Center Hamburg, University Medical Center Hamburg-Eppendorf"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"DZHK (German Centre for Cardiovascular Research), Partner Site North","institution_ids":["https://openalex.org/I4210127591"]},{"raw_affiliation_string":"Department of Cardiac Surgery, University Heart and Vascular Center Hamburg, University Medical Center Hamburg-Eppendorf","institution_ids":["https://openalex.org/I159176309","https://openalex.org/I4210108711"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5025433178","display_name":"Evelina Macius","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I159176309","display_name":"Universit\u00e4t Hamburg","ror":"https://ror.org/00g30e956","country_code":"DE","type":"education","lineage":["https://openalex.org/I159176309"]},{"id":"https://openalex.org/I4210108711","display_name":"University Medical Center Hamburg-Eppendorf","ror":"https://ror.org/01zgy1s35","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I159176309","https://openalex.org/I4210108711"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Evelina Macius","raw_affiliation_strings":["Department of Cardiac Surgery, University Heart and Vascular Center Hamburg, University Medical Center Hamburg-Eppendorf"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cardiac Surgery, University Heart and Vascular Center Hamburg, University Medical Center Hamburg-Eppendorf","institution_ids":["https://openalex.org/I159176309","https://openalex.org/I4210108711"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5040011109","display_name":"Oliver Daniel Bhadra","orcid":"https://orcid.org/0009-0005-3840-6844","observed_orcids":["https://orcid.org/0009-0005-3840-6844"]},"institutions":[{"id":"https://openalex.org/I159176309","display_name":"Universit\u00e4t Hamburg","ror":"https://ror.org/00g30e956","country_code":"DE","type":"education","lineage":["https://openalex.org/I159176309"]},{"id":"https://openalex.org/I4210108711","display_name":"University Medical Center Hamburg-Eppendorf","ror":"https://ror.org/01zgy1s35","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I159176309","https://openalex.org/I4210108711"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Oliver Bhadra","raw_affiliation_strings":["Department of Cardiac Surgery, University Heart and Vascular Center Hamburg, University Medical Center Hamburg-Eppendorf"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cardiac Surgery, University Heart and Vascular Center Hamburg, University Medical Center Hamburg-Eppendorf","institution_ids":["https://openalex.org/I159176309","https://openalex.org/I4210108711"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5022965253","display_name":"Y. Alassar","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I159176309","display_name":"Universit\u00e4t Hamburg","ror":"https://ror.org/00g30e956","country_code":"DE","type":"education","lineage":["https://openalex.org/I159176309"]},{"id":"https://openalex.org/I4210108711","display_name":"University Medical Center Hamburg-Eppendorf","ror":"https://ror.org/01zgy1s35","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I159176309","https://openalex.org/I4210108711"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Yousuf Alassar","raw_affiliation_strings":["Department of Cardiac Surgery, University Heart and Vascular Center Hamburg, University Medical Center Hamburg-Eppendorf"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cardiac Surgery, University Heart and Vascular Center Hamburg, University Medical Center Hamburg-Eppendorf","institution_ids":["https://openalex.org/I159176309","https://openalex.org/I4210108711"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5076530925","display_name":"Benjamin Kloth","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I159176309","display_name":"Universit\u00e4t Hamburg","ror":"https://ror.org/00g30e956","country_code":"DE","type":"education","lineage":["https://openalex.org/I159176309"]},{"id":"https://openalex.org/I4210108711","display_name":"University Medical Center Hamburg-Eppendorf","ror":"https://ror.org/01zgy1s35","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I159176309","https://openalex.org/I4210108711"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Benjamin Kloth","raw_affiliation_strings":["Department of Cardiac Surgery, University Heart and Vascular Center Hamburg, University Medical Center Hamburg-Eppendorf"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cardiac Surgery, University Heart and Vascular Center Hamburg, University Medical Center Hamburg-Eppendorf","institution_ids":["https://openalex.org/I159176309","https://openalex.org/I4210108711"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5123364100","display_name":"Lenard Conradi","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210153755","display_name":"University Hospital Cologne","ror":"https://ror.org/05mxhda18","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I4210153755"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Lenard Conradi","raw_affiliation_strings":["Department of Cardiac Surgery, University Hospital Cologne"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cardiac Surgery, University Hospital Cologne","institution_ids":["https://openalex.org/I4210153755"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5076167190","display_name":"Hermann C. Reichenspurner","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I159176309","display_name":"Universit\u00e4t Hamburg","ror":"https://ror.org/00g30e956","country_code":"DE","type":"education","lineage":["https://openalex.org/I159176309"]},{"id":"https://openalex.org/I4210108711","display_name":"University Medical Center Hamburg-Eppendorf","ror":"https://ror.org/01zgy1s35","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I159176309","https://openalex.org/I4210108711"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Hermann Reichenspurner","raw_affiliation_strings":["Department of Cardiac Surgery, University Heart and Vascular Center Hamburg, University Medical Center Hamburg-Eppendorf"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cardiac Surgery, University Heart and Vascular Center Hamburg, University Medical Center Hamburg-Eppendorf","institution_ids":["https://openalex.org/I159176309","https://openalex.org/I4210108711"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5000972847","display_name":"Simon Pecha","orcid":"https://orcid.org/0000-0002-8747-166X","observed_orcids":["https://orcid.org/0000-0002-8747-166X"]},"institutions":[{"id":"https://openalex.org/I159176309","display_name":"Universit\u00e4t Hamburg","ror":"https://ror.org/00g30e956","country_code":"DE","type":"education","lineage":["https://openalex.org/I159176309"]},{"id":"https://openalex.org/I4210108711","display_name":"University Medical Center Hamburg-Eppendorf","ror":"https://ror.org/01zgy1s35","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I159176309","https://openalex.org/I4210108711"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Simon Pecha","raw_affiliation_strings":["Department of Cardiac Surgery, University Heart and Vascular Center Hamburg, University Medical Center Hamburg-Eppendorf"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cardiac Surgery, University Heart and Vascular Center Hamburg, University Medical Center Hamburg-Eppendorf","institution_ids":["https://openalex.org/I159176309","https://openalex.org/I4210108711"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5126251765","display_name":"Evaldas Girdauskas","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I159176309","display_name":"Universit\u00e4t Hamburg","ror":"https://ror.org/00g30e956","country_code":"DE","type":"education","lineage":["https://openalex.org/I159176309"]},{"id":"https://openalex.org/I4210108711","display_name":"University Medical Center Hamburg-Eppendorf","ror":"https://ror.org/01zgy1s35","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I159176309","https://openalex.org/I4210108711"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Evaldas Girdauskas","raw_affiliation_strings":["Department of Cardiac Surgery, University Heart and Vascular Center Hamburg, University Medical Center Hamburg-Eppendorf"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cardiac Surgery, University Heart and Vascular Center Hamburg, University Medical Center Hamburg-Eppendorf","institution_ids":["https://openalex.org/I159176309","https://openalex.org/I4210108711"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5006616766","display_name":"Andreas Schaefer","orcid":"https://orcid.org/0000-0001-7304-6083","observed_orcids":["https://orcid.org/0000-0001-7304-6083"]},"institutions":[{"id":"https://openalex.org/I159176309","display_name":"Universit\u00e4t Hamburg","ror":"https://ror.org/00g30e956","country_code":"DE","type":"education","lineage":["https://openalex.org/I159176309"]},{"id":"https://openalex.org/I4210108711","display_name":"University Medical Center Hamburg-Eppendorf","ror":"https://ror.org/01zgy1s35","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I159176309","https://openalex.org/I4210108711"]}],"countries":["DE"],"is_corresponding":true,"raw_author_name":"Andreas Schaefer","raw_affiliation_strings":["Department of Cardiac Surgery, University Heart and Vascular Center Hamburg, University Medical Center Hamburg-Eppendorf"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cardiac Surgery, University Heart and Vascular Center Hamburg, University Medical Center Hamburg-Eppendorf","institution_ids":["https://openalex.org/I159176309","https://openalex.org/I4210108711"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5006616766"],"corresponding_institution_ids":["https://openalex.org/I159176309","https://openalex.org/I4210108711"],"apc_list":{"value":3150,"currency":"CHF","value_usd":3801},"apc_paid":{"value":3150,"currency":"CHF","value_usd":3801},"fwci":0.0,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":{"value":0.79313632,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"13","issue":null,"first_page":"1903773","last_page":"1903773"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10172","display_name":"Cardiac Valve Diseases and Treatments","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10172","display_name":"Cardiac Valve Diseases and Treatments","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11055","display_name":"Cardiac and Coronary Surgery Techniques","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11217","display_name":"Cardiac Arrhythmias and Treatments","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/mitral-valve-replacement","display_name":"mitral valve replacement","score":0.8510000109672546},{"id":"https://openalex.org/keywords/mitral-regurgitation","display_name":"mitral regurgitation","score":0.8360000252723694},{"id":"https://openalex.org/keywords/mitral-valve-repair","display_name":"mitral valve repair","score":0.8029999732971191},{"id":"https://openalex.org/keywords/mitral-stenosis","display_name":"mitral stenosis","score":0.8730000257492065},{"id":"https://openalex.org/keywords/endocarditis","display_name":"endocarditis","score":0.7919999957084656},{"id":"https://openalex.org/keywords/long-term-outcomes","display_name":"long-term outcomes","score":0.6499999761581421},{"id":"https://openalex.org/keywords/5-year-survival","display_name":"five-year survival","score":0.7089999914169312},{"id":"https://openalex.org/keywords/reintervention","display_name":"reintervention","score":0.6480000019073486},{"id":"https://openalex.org/keywords/transvalvular-pressure-gradient","display_name":"transvalvular gradient","score":0.7120000123977661},{"id":"https://openalex.org/keywords/permanent-pacemaker-implantation","display_name":"permanent pacemaker implantation","score":0.6660000085830688}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9789999723434448},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.7049000263214111},{"id":"https://openalex.org/C2780679668","wikidata":"https://www.wikidata.org/wiki/Q6882374","display_name":"Mitral valve repair","level":3,"score":0.623199999332428},{"id":"https://openalex.org/C2993373945","wikidata":"https://www.wikidata.org/wiki/Q268292","display_name":"Mitral regurgitation","level":2,"score":0.5849999785423279},{"id":"https://openalex.org/C2780007028","wikidata":"https://www.wikidata.org/wiki/Q2343082","display_name":"Stenosis","level":2,"score":0.5710999965667725},{"id":"https://openalex.org/C2775854548","wikidata":"https://www.wikidata.org/wiki/Q6882369","display_name":"Mitral valve replacement","level":3,"score":0.4499000012874603},{"id":"https://openalex.org/C2779159551","wikidata":"https://www.wikidata.org/wiki/Q1414874","display_name":"Comorbidity","level":2,"score":0.4325999915599823},{"id":"https://openalex.org/C2780026749","wikidata":"https://www.wikidata.org/wiki/Q7912830","display_name":"Valve replacement","level":3,"score":0.41999998688697815},{"id":"https://openalex.org/C164705383","wikidata":"https://www.wikidata.org/wiki/Q10379","display_name":"Cardiology","level":1,"score":0.41359999775886536},{"id":"https://openalex.org/C2775872228","wikidata":"https://www.wikidata.org/wiki/Q82504","display_name":"Endocarditis","level":2,"score":0.41290000081062317},{"id":"https://openalex.org/C2780073493","wikidata":"https://www.wikidata.org/wiki/Q7523837","display_name":"Single Center","level":2,"score":0.37439998984336853},{"id":"https://openalex.org/C2777543888","wikidata":"https://www.wikidata.org/wiki/Q369939","display_name":"Mitral valve","level":2,"score":0.34369999170303345},{"id":"https://openalex.org/C2780176578","wikidata":"https://www.wikidata.org/wiki/Q2450598","display_name":"Infective endocarditis","level":2,"score":0.34220001101493835},{"id":"https://openalex.org/C17923572","wikidata":"https://www.wikidata.org/wiki/Q7250160","display_name":"Propensity score matching","level":2,"score":0.32690000534057617},{"id":"https://openalex.org/C179755657","wikidata":"https://www.wikidata.org/wiki/Q58702","display_name":"Mortality rate","level":2,"score":0.3109999895095825},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.30230000615119934},{"id":"https://openalex.org/C2780168065","wikidata":"https://www.wikidata.org/wiki/Q1930043","display_name":"Regurgitation (circulation)","level":2,"score":0.299699991941452},{"id":"https://openalex.org/C2908602593","wikidata":"https://www.wikidata.org/wiki/Q268292","display_name":"Mitral incompetence","level":3,"score":0.28769999742507935},{"id":"https://openalex.org/C167135981","wikidata":"https://www.wikidata.org/wiki/Q2146302","display_name":"Retrospective cohort study","level":2,"score":0.28690001368522644},{"id":"https://openalex.org/C2776283816","wikidata":"https://www.wikidata.org/wiki/Q332823","display_name":"Survival rate","level":2,"score":0.28459998965263367},{"id":"https://openalex.org/C2779433084","wikidata":"https://www.wikidata.org/wiki/Q5004192","display_name":"Bypass surgery","level":3,"score":0.28279998898506165},{"id":"https://openalex.org/C3019894029","wikidata":"https://www.wikidata.org/wiki/Q332823","display_name":"Overall survival","level":2,"score":0.2808000147342682},{"id":"https://openalex.org/C2776570981","wikidata":"https://www.wikidata.org/wiki/Q4413093","display_name":"Aortic valve replacement","level":3,"score":0.27129998803138733},{"id":"https://openalex.org/C2780074459","wikidata":"https://www.wikidata.org/wiki/Q389735","display_name":"Heart disease","level":2,"score":0.2612000107765198},{"id":"https://openalex.org/C2778583881","wikidata":"https://www.wikidata.org/wiki/Q1325542","display_name":"Stent","level":2,"score":0.25369998812675476},{"id":"https://openalex.org/C2778451229","wikidata":"https://www.wikidata.org/wiki/Q212809","display_name":"Endoscopy","level":2,"score":0.2524000108242035}],"mesh":[],"locations_count":4,"locations":[{"id":"doi:10.3389/fcvm.2026.1903773","doi":"https://doi.org/10.3389/fcvm.2026.1903773","is_oa":true,"landing_page_url":"https://doi.org/10.3389/fcvm.2026.1903773","pdf_url":"https://www.frontiersin.org/journals/cardiovascular-medicine/articles/10.3389/fcvm.2026.1903773/pdf","source":{"id":"https://openalex.org/S2595413687","display_name":"Frontiers in Cardiovascular Medicine","issn_l":"2297-055X","issn":["2297-055X"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","jufo-1","ki-jl-1","norway-1","poland-40","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320527","host_organization_name":"Frontiers Media","host_organization_lineage":["https://openalex.org/P4310320527"],"host_organization_lineage_names":["Frontiers Media"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in Cardiovascular Medicine","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:13727415","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC13727415/","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC13727415/pdf/fcvm-13-1903773.pdf","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Front Cardiovasc Med","raw_type":"Text"},{"id":"pmid:42978567","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/42978567","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in cardiovascular medicine","raw_type":"Journal Article"},{"id":"pmh:oai:doaj.org/article:77e3cc8d64e8493e95281ede82eb6e93","doi":null,"is_oa":false,"landing_page_url":"https://doaj.org/article/77e3cc8d64e8493e95281ede82eb6e93","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Frontiers in Cardiovascular Medicine, Vol 13 (2026)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.3389/fcvm.2026.1903773","doi":"https://doi.org/10.3389/fcvm.2026.1903773","is_oa":true,"landing_page_url":"https://doi.org/10.3389/fcvm.2026.1903773","pdf_url":"https://www.frontiersin.org/journals/cardiovascular-medicine/articles/10.3389/fcvm.2026.1903773/pdf","source":{"id":"https://openalex.org/S2595413687","display_name":"Frontiers in Cardiovascular Medicine","issn_l":"2297-055X","issn":["2297-055X"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","jufo-1","ki-jl-1","norway-1","poland-40","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320527","host_organization_name":"Frontiers Media","host_organization_lineage":["https://openalex.org/P4310320527"],"host_organization_lineage_names":["Frontiers Media"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in Cardiovascular Medicine","raw_type":"journal-article"},"sustainable_development_goals":[{"score":1.0,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W7223054536.pdf","grobid_xml":"https://content.openalex.org/works/W7223054536.grobid-xml"},"referenced_works_count":34,"referenced_works":["https://openalex.org/W1845635296","https://openalex.org/W1967927259","https://openalex.org/W1989252516","https://openalex.org/W2009654793","https://openalex.org/W2013823704","https://openalex.org/W2016911992","https://openalex.org/W2066927687","https://openalex.org/W2099982366","https://openalex.org/W2107617215","https://openalex.org/W2112323503","https://openalex.org/W2122694177","https://openalex.org/W2156378925","https://openalex.org/W2191399290","https://openalex.org/W2193849676","https://openalex.org/W2297730185","https://openalex.org/W2414221325","https://openalex.org/W2520838835","https://openalex.org/W2809127278","https://openalex.org/W2945954951","https://openalex.org/W2987601365","https://openalex.org/W3082273768","https://openalex.org/W3135326068","https://openalex.org/W3158898376","https://openalex.org/W3195842247","https://openalex.org/W4200422439","https://openalex.org/W4292290582","https://openalex.org/W4380480637","https://openalex.org/W4390534977","https://openalex.org/W4402125899","https://openalex.org/W4403714622","https://openalex.org/W4406087349","https://openalex.org/W4407367579","https://openalex.org/W4411329453","https://openalex.org/W4416553914"],"related_works":["https://openalex.org/W4407367439","https://openalex.org/W7165683049","https://openalex.org/W2066927687","https://openalex.org/W2901157807","https://openalex.org/W2366700957","https://openalex.org/W7204790614","https://openalex.org/W3140246614","https://openalex.org/W4404733841","https://openalex.org/W4406087349","https://openalex.org/W7170133295"],"abstract_inverted_index":{"Objectives":[0],"Totally":[1,192,234],"endoscopic":[2,41,58,193,235],"mitral":[3,12],"valve":[4],"(MV)":[5],"surgery":[6,195],"is":[7,27,200],"an":[8],"established":[9],"therapy":[10],"for":[11,39,97,247],"regurgitation":[13],"(MR)":[14],"with":[15,203],"high":[16],"repair":[17,26,87,110,122],"rates":[18,148,185],"at":[19,156,196],"experienced":[20],"centers.":[21],"In":[22],"certain":[23],"scenarios,":[24],"however,":[25],"not":[28],"feasible,":[29],"necessitating":[30],"chordal-sparing":[31,67,236],"MV":[32,42,59,68,98,106,194,204,213,237],"replacement.":[33,69,205],"This":[34],"study":[35],"investigates":[36],"the":[37],"reasons":[38,208],"totally":[40,57],"replacement":[43,99,143,161,238],"and":[44,51,74,80,116,125,183,215,222,229,242],"reports":[45],"5-year":[46],"outcomes.":[47],"Methods":[48],"Between":[49],"2012":[50],"2022,":[52],"1,037":[53],"consecutive":[54],"patients":[55,64],"underwent":[56,66],"surgery.":[60],"Of":[61],"those,":[62],"75":[63],"(7.2%)":[65],"Preoperative":[70],"characteristics,":[71],"periprocedural":[72],"data,":[73],"mid-term":[75,230],"outcomes":[76,231],"were":[77,94,128,149,158,186,232],"retrospectively":[78],"analyzed":[79],"compared":[81],"to":[82],"a":[83,197,218,240],"1:1":[84],"propensity":[85],"score-matched":[86],"group.":[88],"Results":[89],"After":[90],"matching,":[91,227],"baseline":[92,224],"characteristics":[93],"balanced.":[95],"Indications":[96],"included":[100,209],"sclerotic":[101,210],"leaflets":[102],"(28.0%),":[103],"endocarditis":[104],"(26.7%),":[105],"stenosis":[107],"(17.3%),":[108,112],"failed":[109],"attempt":[111],"rheumatic":[113],"disease":[114],"(12.0%),":[115],"residual":[117,223],"MR":[118],"after":[119,142,160,226],"transcatheter":[120],"edge-to-edge":[121],"(7%).":[123],"Cross-clamp":[124],"bypass":[126],"times":[127],"similar.":[129],"Re-thoracotomy":[130],"occurred":[131,140],"in":[132],"14.7%":[133],"vs.":[134,152,175,181,189],"6.7%,":[135],"while":[136],"permanent":[137],"pacemaker":[138],"implantation":[139],"solely":[141],"(16.0%).":[144],"Low":[145],"cardiac":[146],"output":[147],"comparable":[150],"(6.7%":[151],"5.5%).":[153],"Transvalvular":[154],"gradients":[155],"discharge":[157],"higher":[159,219],"(":[162],"p":[163],"<":[164],"0.001).":[165],"No":[166],"paravalvular":[167],"leakage":[168],"was":[169,173,179],"observed.":[170],"In-hospital":[171],"mortality":[172],"4%":[174],"0%.":[176],"Five-year":[177],"survival":[178],"86.7%":[180],"94.7%,":[182],"reintervention":[184],"similar":[187],"(4.0%":[188],"6.7%).":[190],"Conclusion":[191],"high-volume":[198],"center":[199],"infrequently":[201],"associated":[202],"The":[206],"main":[207],"leaflet":[211],"pathology,":[212],"stenosis,":[214],"endocarditis.":[216],"Despite":[217],"comorbidity":[220],"burden":[221],"imbalance":[225],"early":[228],"acceptable.":[233],"represents":[239],"safe":[241],"clinically":[243],"effective":[244],"treatment":[245],"option":[246],"selected":[248],"patients.":[249]},"counts_by_year":[],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2026-10-21T00:00:00"}