{"id":"https://openalex.org/W7223042402","doi":"https://doi.org/10.4047/jap.2026.18.5.508","title":"Clinical outcomes of a novel one-piece niobia-modified zirconia implant compared with a titanium implant at 48 weeks: a multicenter randomized controlled trial","display_name":"Clinical outcomes of a novel one-piece niobia-modified zirconia implant compared with a titanium implant at 48 weeks: a multicenter randomized controlled trial","publication_year":2026,"publication_date":"2026-01-01","ids":{"openalex":"https://openalex.org/W7223042402","doi":"https://doi.org/10.4047/jap.2026.18.5.508","pmid":"https://pubmed.ncbi.nlm.nih.gov/42948547","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/13713208"},"language":"en","primary_location":{"id":"doi:10.4047/jap.2026.18.5.508","doi":"https://doi.org/10.4047/jap.2026.18.5.508","is_oa":true,"landing_page_url":"https://doi.org/10.4047/jap.2026.18.5.508","pdf_url":null,"source":{"id":"https://openalex.org/S51937049","display_name":"The Journal of Advanced Prosthodontics","issn_l":"2005-7806","issn":["2005-7806","2005-7814"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","jufo-1","kci-registered","poland-100","russia-white-list-2"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of Advanced Prosthodontics","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"diamond","oa_url":"https://doi.org/10.4047/jap.2026.18.5.508","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5159104253","display_name":"Yee Hyun Kim","orcid":"https://orcid.org/0009-0004-9856-9189","observed_orcids":["https://orcid.org/0009-0004-9856-9189"]},"institutions":[{"id":"https://openalex.org/I2801680663","display_name":"Asan Medical Center","ror":"https://ror.org/03s5q0090","country_code":"KR","type":"healthcare","lineage":["https://openalex.org/I2801680663","https://openalex.org/I4210167194"]},{"id":"https://openalex.org/I40542001","display_name":"University of Ulsan","ror":"https://ror.org/02c2f8975","country_code":"KR","type":"education","lineage":["https://openalex.org/I40542001"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Yee Hyun Kim","raw_affiliation_strings":["Department of Periodontology, University of Ulsan College of Medicine and Asan Medical Center, Seoul, Republic of Korea"],"raw_orcid":"https://orcid.org/0009-0004-9856-9189","affiliations":[{"raw_affiliation_string":"Department of Periodontology, University of Ulsan College of Medicine and Asan Medical Center, Seoul, Republic of Korea","institution_ids":["https://openalex.org/I2801680663","https://openalex.org/I40542001"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5159136998","display_name":"Yeonsoo Seo","orcid":"https://orcid.org/0009-0004-6942-9654","observed_orcids":["https://orcid.org/0009-0004-6942-9654"]},"institutions":[{"id":"https://openalex.org/I139264467","display_name":"Seoul National University","ror":"https://ror.org/04h9pn542","country_code":"KR","type":"education","lineage":["https://openalex.org/I139264467"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Yeonsoo Seo","raw_affiliation_strings":["Department of Periodontology, School of Dentistry and Dental Research Institute, Seoul National University, Seoul, Republic of Korea"],"raw_orcid":"https://orcid.org/0009-0004-6942-9654","affiliations":[{"raw_affiliation_string":"Department of Periodontology, School of Dentistry and Dental Research Institute, Seoul National University, Seoul, Republic of Korea","institution_ids":["https://openalex.org/I139264467"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5084232965","display_name":"Kyoung-Hwa Kim","orcid":"https://orcid.org/0000-0001-5611-1242","observed_orcids":["https://orcid.org/0000-0001-5611-1242","https://orcid.org/0009-0008-3037-2792"]},"institutions":[{"id":"https://openalex.org/I139264467","display_name":"Seoul National University","ror":"https://ror.org/04h9pn542","country_code":"KR","type":"education","lineage":["https://openalex.org/I139264467"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Kyoung-Hwa Kim","raw_affiliation_strings":["Department of Periodontology, School of Dentistry and Dental Research Institute, Seoul National University, Seoul, Republic of Korea"],"raw_orcid":"https://orcid.org/0000-0001-5611-1242","affiliations":[{"raw_affiliation_string":"Department of Periodontology, School of Dentistry and Dental Research Institute, Seoul National University, Seoul, Republic of Korea","institution_ids":["https://openalex.org/I139264467"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5021432742","display_name":"Young\u2010Sung Kim","orcid":"https://orcid.org/0000-0003-2674-3649","observed_orcids":["https://orcid.org/0000-0003-2674-3649"]},"institutions":[{"id":"https://openalex.org/I2801680663","display_name":"Asan Medical Center","ror":"https://ror.org/03s5q0090","country_code":"KR","type":"healthcare","lineage":["https://openalex.org/I2801680663","https://openalex.org/I4210167194"]},{"id":"https://openalex.org/I40542001","display_name":"University of Ulsan","ror":"https://ror.org/02c2f8975","country_code":"KR","type":"education","lineage":["https://openalex.org/I40542001"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Young-Sung Kim","raw_affiliation_strings":["Department of Periodontology, University of Ulsan College of Medicine and Asan Medical Center, Seoul, Republic of Korea"],"raw_orcid":"https://orcid.org/0000-0003-2674-3649","affiliations":[{"raw_affiliation_string":"Department of Periodontology, University of Ulsan College of Medicine and Asan Medical Center, Seoul, Republic of Korea","institution_ids":["https://openalex.org/I2801680663","https://openalex.org/I40542001"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5069919466","display_name":"Chang\u2010Joo Park","orcid":"https://orcid.org/0000-0002-6895-9854","observed_orcids":["https://orcid.org/0000-0002-6895-9854"]},"institutions":[{"id":"https://openalex.org/I4575257","display_name":"Hanyang University","ror":"https://ror.org/046865y68","country_code":"KR","type":"education","lineage":["https://openalex.org/I4575257"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Chang-Joo Park","raw_affiliation_strings":["Division of Oral and Maxillofacial Surgery, Department of Dentistry, College of Medicine, Hanyang University, Seoul, Republic of Korea"],"raw_orcid":"https://orcid.org/0000-0002-6895-9854","affiliations":[{"raw_affiliation_string":"Division of Oral and Maxillofacial Surgery, Department of Dentistry, College of Medicine, Hanyang University, Seoul, Republic of Korea","institution_ids":["https://openalex.org/I4575257"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100673130","display_name":"Junho Cho","orcid":"https://orcid.org/0000-0002-1416-7915","observed_orcids":["https://orcid.org/0000-0002-1416-7915"]},"institutions":[{"id":"https://openalex.org/I139264467","display_name":"Seoul National University","ror":"https://ror.org/04h9pn542","country_code":"KR","type":"education","lineage":["https://openalex.org/I139264467"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Jun-Ho Cho","raw_affiliation_strings":["Department of Prosthodontics, School of Dentistry and Dental Research Institute, Seoul National University, Seoul, Republic of Korea"],"raw_orcid":"https://orcid.org/0000-0002-1416-7915","affiliations":[{"raw_affiliation_string":"Department of Prosthodontics, School of Dentistry and Dental Research Institute, Seoul National University, Seoul, Republic of Korea","institution_ids":["https://openalex.org/I139264467"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5070983622","display_name":"Dae\u2010Joon Kim","orcid":"https://orcid.org/0000-0003-3693-7762","observed_orcids":["https://orcid.org/0000-0003-3693-7762"]},"institutions":[{"id":"https://openalex.org/I139264467","display_name":"Seoul National University","ror":"https://ror.org/04h9pn542","country_code":"KR","type":"education","lineage":["https://openalex.org/I139264467"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Dae-Joon Kim","raw_affiliation_strings":["Dental Research Institute, Seoul National University, Seoul, Republic of Korea"],"raw_orcid":"https://orcid.org/0000-0003-3693-7762","affiliations":[{"raw_affiliation_string":"Dental Research Institute, Seoul National University, Seoul, Republic of Korea","institution_ids":["https://openalex.org/I139264467"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5053511327","display_name":"Yang\u2010Jo Seol","orcid":"https://orcid.org/0000-0002-2076-5452","observed_orcids":["https://orcid.org/0000-0002-2076-5452"]},"institutions":[{"id":"https://openalex.org/I139264467","display_name":"Seoul National University","ror":"https://ror.org/04h9pn542","country_code":"KR","type":"education","lineage":["https://openalex.org/I139264467"]}],"countries":["KR"],"is_corresponding":true,"raw_author_name":"Yang-Jo Seol","raw_affiliation_strings":["Department of Periodontology, School of Dentistry and Dental Research Institute, Seoul National University, Seoul, Republic of Korea"],"raw_orcid":"https://orcid.org/0000-0002-2076-5452","affiliations":[{"raw_affiliation_string":"Department of Periodontology, School of Dentistry and Dental Research Institute, Seoul National University, Seoul, Republic of Korea","institution_ids":["https://openalex.org/I139264467"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5016373597","display_name":"In-Sung Luke Yeo","orcid":"https://orcid.org/0000-0002-6780-2601","observed_orcids":["https://orcid.org/0000-0002-6780-2601"]},"institutions":[{"id":"https://openalex.org/I139264467","display_name":"Seoul National University","ror":"https://ror.org/04h9pn542","country_code":"KR","type":"education","lineage":["https://openalex.org/I139264467"]}],"countries":["KR"],"is_corresponding":true,"raw_author_name":"In-Sung Luke Yeo","raw_affiliation_strings":["Department of Prosthodontics, School of Dentistry and Dental Research Institute, Seoul National University, Seoul, Republic of Korea"],"raw_orcid":"https://orcid.org/0000-0002-6780-2601","affiliations":[{"raw_affiliation_string":"Department of Prosthodontics, School of Dentistry and Dental Research Institute, Seoul National University, Seoul, Republic of Korea","institution_ids":["https://openalex.org/I139264467"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5016373597","https://openalex.org/A5053511327"],"corresponding_institution_ids":["https://openalex.org/I139264467"],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":{"value":0.81825193,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"18","issue":"5","first_page":"508","last_page":"508"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10359","display_name":"Dental Implant Techniques and Outcomes","score":0.9955999851226807,"subfield":{"id":"https://openalex.org/subfields/3504","display_name":"Oral Surgery"},"field":{"id":"https://openalex.org/fields/35","display_name":"Dentistry"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10359","display_name":"Dental Implant Techniques and Outcomes","score":0.9955999851226807,"subfield":{"id":"https://openalex.org/subfields/3504","display_name":"Oral Surgery"},"field":{"id":"https://openalex.org/fields/35","display_name":"Dentistry"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10113","display_name":"Dental materials and restorations","score":0.0031999999191612005,"subfield":{"id":"https://openalex.org/subfields/3500","display_name":"General Dentistry"},"field":{"id":"https://openalex.org/fields/35","display_name":"Dentistry"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10512","display_name":"Orthopaedic implants and arthroplasty","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/yttria-stabilized-tetragonal-zirconia-polycrystal","display_name":"yttria-stabilized tetragonal zirconia polycrystal","score":0.9359999895095825},{"id":"https://openalex.org/keywords/one-piece-implants","display_name":"one-piece implants","score":0.6389999985694885},{"id":"https://openalex.org/keywords/titanium-implants","display_name":"titanium implants","score":0.746999979019165},{"id":"https://openalex.org/keywords/marginal-bone-level","display_name":"marginal bone level","score":0.7210000157356262},{"id":"https://openalex.org/keywords/non-inferiority","display_name":"non-inferiority","score":0.8240000009536743},{"id":"https://openalex.org/keywords/peri-implant-soft-tissue","display_name":"peri-implant soft tissue","score":0.753000020980835},{"id":"https://openalex.org/keywords/monolithic-zirconia-crowns","display_name":"monolithic zirconia crowns","score":0.75}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8835999965667725},{"id":"https://openalex.org/C168563851","wikidata":"https://www.wikidata.org/wiki/Q1436668","display_name":"Randomized controlled trial","level":2,"score":0.7979999780654907},{"id":"https://openalex.org/C2781411149","wikidata":"https://www.wikidata.org/wiki/Q486975","display_name":"Implant","level":2,"score":0.697700023651123},{"id":"https://openalex.org/C506065880","wikidata":"https://www.wikidata.org/wiki/Q716","display_name":"Titanium","level":2,"score":0.5026000142097473},{"id":"https://openalex.org/C2992435398","wikidata":"https://www.wikidata.org/wiki/Q6934595","display_name":"Multicenter study","level":3,"score":0.4684999883174896},{"id":"https://openalex.org/C199343813","wikidata":"https://www.wikidata.org/wiki/Q12128","display_name":"Dentistry","level":1,"score":0.43070000410079956},{"id":"https://openalex.org/C2775965419","wikidata":"https://www.wikidata.org/wiki/Q6934595","display_name":"Multicenter trial","level":4,"score":0.4277999997138977},{"id":"https://openalex.org/C535046627","wikidata":"https://www.wikidata.org/wiki/Q30612","display_name":"Clinical trial","level":2,"score":0.3837999999523163},{"id":"https://openalex.org/C123609680","wikidata":"https://www.wikidata.org/wiki/Q225666","display_name":"Cubic zirconia","level":3,"score":0.34549999237060547},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.32350000739097595},{"id":"https://openalex.org/C1318750","wikidata":"https://www.wikidata.org/wiki/Q865663","display_name":"Biocompatible material","level":2,"score":0.28450000286102295},{"id":"https://openalex.org/C3019548353","wikidata":"https://www.wikidata.org/wiki/Q181802","display_name":"Prosthesis design","level":3,"score":0.25999999046325684}],"mesh":[],"locations_count":3,"locations":[{"id":"doi:10.4047/jap.2026.18.5.508","doi":"https://doi.org/10.4047/jap.2026.18.5.508","is_oa":true,"landing_page_url":"https://doi.org/10.4047/jap.2026.18.5.508","pdf_url":null,"source":{"id":"https://openalex.org/S51937049","display_name":"The Journal of Advanced Prosthodontics","issn_l":"2005-7806","issn":["2005-7806","2005-7814"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","jufo-1","kci-registered","poland-100","russia-white-list-2"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of Advanced Prosthodontics","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:13713208","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC13713208/","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC13713208/pdf/jap-18-508.pdf","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"J Adv Prosthodont","raw_type":"Text"},{"id":"pmid:42948547","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/42948547","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The journal of advanced prosthodontics","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.4047/jap.2026.18.5.508","doi":"https://doi.org/10.4047/jap.2026.18.5.508","is_oa":true,"landing_page_url":"https://doi.org/10.4047/jap.2026.18.5.508","pdf_url":null,"source":{"id":"https://openalex.org/S51937049","display_name":"The Journal of Advanced Prosthodontics","issn_l":"2005-7806","issn":["2005-7806","2005-7814"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","jufo-1","kci-registered","poland-100","russia-white-list-2"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of Advanced Prosthodontics","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.9922999739646912,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/randomized-controlled-trial","display_name":"Randomized Controlled Trial"},{"id":"https://openalex.org/study-designs/clinical-trial","display_name":"Clinical Trial"}],"awards":[{"id":"https://openalex.org/G8086594992","display_name":null,"funder_award_id":"RS-2020-KD000105","funder_id":"https://openalex.org/F4320318847","funder_display_name":"Korea Medical Device Development Fund"},{"id":"https://openalex.org/G8182657796","display_name":null,"funder_award_id":"RS-2020-KD000105","funder_id":"https://openalex.org/F4320322014","funder_display_name":"Ministry of Food and Drug Safety"}],"funders":[{"id":"https://openalex.org/F4320318847","display_name":"Korea Medical Device Development Fund","ror":"https://ror.org/03g98ap29"},{"id":"https://openalex.org/F4320321142","display_name":"Hanyang University","ror":"https://ror.org/046865y68"},{"id":"https://openalex.org/F4320321292","display_name":"Seoul National University","ror":"https://ror.org/04h9pn542"},{"id":"https://openalex.org/F4320321681","display_name":"Ministry of Trade, Industry and Energy","ror":"https://ror.org/008nkqk13"},{"id":"https://openalex.org/F4320322014","display_name":"Ministry of Food and Drug Safety","ror":"https://ror.org/01f7dp456"},{"id":"https://openalex.org/F4320328359","display_name":"Ministry of Science and ICT, South Korea","ror":"https://ror.org/01wpjm123"},{"id":"https://openalex.org/F4320329391","display_name":"Seoul National University Dental Hospital","ror":"https://ror.org/0494zgc81"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W7223042402.pdf","grobid_xml":"https://content.openalex.org/works/W7223042402.grobid-xml"},"referenced_works_count":34,"referenced_works":["https://openalex.org/W1870957361","https://openalex.org/W1967076724","https://openalex.org/W1979164497","https://openalex.org/W1982749880","https://openalex.org/W2007239126","https://openalex.org/W2031806889","https://openalex.org/W2059226182","https://openalex.org/W2076008117","https://openalex.org/W2091923662","https://openalex.org/W2094327218","https://openalex.org/W2101101596","https://openalex.org/W2116369314","https://openalex.org/W2121016728","https://openalex.org/W2147186719","https://openalex.org/W2148689027","https://openalex.org/W2162835535","https://openalex.org/W2379248761","https://openalex.org/W2756022119","https://openalex.org/W2801931244","https://openalex.org/W2913286657","https://openalex.org/W2941905571","https://openalex.org/W3000920627","https://openalex.org/W3048289146","https://openalex.org/W3151227294","https://openalex.org/W3201467980","https://openalex.org/W4281295774","https://openalex.org/W4307711830","https://openalex.org/W4313311914","https://openalex.org/W4390144438","https://openalex.org/W4392737739","https://openalex.org/W4395094084","https://openalex.org/W4402394007","https://openalex.org/W4403769648","https://openalex.org/W4415604349"],"related_works":["https://openalex.org/W4406070047","https://openalex.org/W7165144889","https://openalex.org/W7056631990","https://openalex.org/W4230039901","https://openalex.org/W4406936992","https://openalex.org/W4255299452","https://openalex.org/W2999588505","https://openalex.org/W4235577196","https://openalex.org/W2325593593","https://openalex.org/W7125487876"],"abstract_inverted_index":{"PURPOSE:":[0],"To":[1,128],"compare":[2],"the":[3,23,98,103,106,190,196,210,240],"clinical":[4,35,225],"outcomes":[5,112],"of":[6,17,78,105,141,156,189,212],"one-piece":[7,55],"niobia-modified":[8],"yttria-stabilized":[9],"tetragonal":[10],"zirconia":[11,87],"polycrystal":[12],"((Y,Nb)-TZP)":[13],"implants":[14,21,221,235],"with":[15,152,271],"those":[16],"clinically":[18],"established":[19,231],"titanium":[20,63,234],"during":[22],"first":[24],"48":[25],"weeks":[26,77],"post-placement.":[27],"MATERIALS":[28],"AND":[29],"METHODS:":[30],"This":[31],"multi-center,":[32],"randomized":[33],"controlled":[34],"trial":[36],"evaluated":[37],"patients":[38],"requiring":[39],"a":[40,59,71,131,138,153,257],"single":[41],"premolar":[42],"or":[43,58],"molar":[44],"implant.":[45,64],"Participants":[46],"underwent":[47],"random":[48],"assignment":[49],"to":[50,230,276],"receive":[51],"either":[52,216],"an":[53],"experimental":[54],"(Y,Nb)-TZP":[56,220],"implant":[57,99,119,181,213,245],"control":[60],"two-piece":[61,232],"transmucosal":[62,233],"The":[65,94,176],"protocol":[66],"comprised":[67],"seven":[68],"visits":[69],"over":[70,236],"one-year":[72],"observation":[73],"period.":[74],"Following":[75],"10":[76],"healing,":[79],"abutment-level":[80],"definitive":[81],"impressions":[82],"were":[83,89,150,164,169],"obtained,":[84],"and":[85,123,168,227,239,279],"monolithic":[86],"crowns":[88],"delivered":[90],"at":[91,102,137],"16":[92],"weeks.":[93],"primary":[95],"outcome":[96],"was":[97,135,184,207,248,254],"success":[100,182,246,261],"rate":[101,183,247],"end":[104],"follow-up":[107,273],"period":[108],"(48":[109],"weeks).":[110],"Secondary":[111],"included":[113],"marginal":[114],"bone":[115],"level":[116,140],"(MBL)":[117],"changes,":[118],"survival,":[120],"esthetic":[121],"scores,":[122],"peri-implant":[124],"soft":[125],"tissue":[126],"status.":[127],"evaluate":[129],"non-inferiority,":[130],"one-sided":[132,191],"statistical":[133],"test":[134],"performed":[136],"significance":[139,154],"0.025.":[142],"For":[143],"all":[144],"other":[145],"comparative":[146],"analyses,":[147],"two-sided":[148],"tests":[149],"applied":[151],"threshold":[155],"0.05.":[157],"RESULTS:":[158],"=":[159],".0408);":[160],"however,":[161,251],"both":[162,263],"differences":[163],"only":[165],"marginally":[166],"significant":[167],"not":[170],"adjusted":[171],"for":[172,180,195,244],"multiple":[173],"secondary":[174],"comparisons.":[175],"prespecified":[177,241],"non-inferiority":[178,242,278],"criterion":[179,243,253],"numerically":[185,249],"met":[186],"(upper":[187],"limit":[188],"97.5%":[192],"confidence":[193],"interval":[194,206],"between-group":[197],"difference,":[198],"0.00%;":[199],"margin,":[200],"10.0":[201],"percentage":[202],"points),":[203],"although":[204],"this":[205,252],"degenerate":[208],"given":[209],"absence":[211],"failures":[214],"in":[215,262],"group.":[217],"CONCLUSION:":[218],"One-piece":[219],"showed":[222],"favorable":[223],"short-term":[224],"performance":[226],"safety":[228],"comparable":[229],"one":[237],"year,":[238],"met;":[250],"assessed":[255],"under":[256],"boundary":[258],"condition":[259],"(100%":[260],"groups)":[264],"that":[265],"limits":[266],"its":[267],"precision.":[268],"Larger":[269],"studies":[270],"longer":[272],"are":[274],"warranted":[275],"confirm":[277],"long-term":[280],"effectiveness.":[281]},"counts_by_year":[],"updated_date":"2026-11-08T12:12:28.789561","created_date":"2026-10-21T00:00:00"}