{"id":"https://openalex.org/W7222916622","doi":"https://doi.org/10.1093/bioinformatics/btag722","title":"MR-MAS: an end-to-end multi-agent system for autonomous Mendelian randomization analysis","display_name":"MR-MAS: an end-to-end multi-agent system for autonomous Mendelian randomization analysis","publication_year":2026,"publication_date":"2026-10-01","ids":{"openalex":"https://openalex.org/W7222916622","doi":"https://doi.org/10.1093/bioinformatics/btag722","pmid":"https://pubmed.ncbi.nlm.nih.gov/42895113","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/13680005"},"language":"en","primary_location":{"id":"doi:10.1093/bioinformatics/btag722","doi":"https://doi.org/10.1093/bioinformatics/btag722","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bioinformatics/btag722","pdf_url":"https://academic.oup.com/bioinformatics/advance-article-pdf/doi/10.1093/bioinformatics/btag722/72089679/btag722.pdf","source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["abdc-a","anvur-class-a","anvur-scientific","ccf-a","cwts-core","doaj","dongbi-b","doyens","jufo-3","ki-jl-2","medline","norway-2","oarl","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://academic.oup.com/bioinformatics/advance-article-pdf/doi/10.1093/bioinformatics/btag722/72089679/btag722.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5151082504","display_name":"Wendi Wei","orcid":"https://orcid.org/0009-0005-5622-2694","observed_orcids":["https://orcid.org/0009-0005-5622-2694"]},"institutions":[{"id":"https://openalex.org/I204823248","display_name":"Huazhong Agricultural University","ror":"https://ror.org/023b72294","country_code":"CN","type":"education","lineage":["https://openalex.org/I204823248"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Wendi Wei","raw_affiliation_strings":["College of Informatics, Huazhong Agricultural University , Wuhan, 430070,"],"raw_orcid":"https://orcid.org/0009-0005-5622-2694","affiliations":[{"raw_affiliation_string":"College of Informatics, Huazhong Agricultural University , Wuhan, 430070,","institution_ids":["https://openalex.org/I204823248"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5159043237","display_name":"Yuling Fan","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I204823248","display_name":"Huazhong Agricultural University","ror":"https://ror.org/023b72294","country_code":"CN","type":"education","lineage":["https://openalex.org/I204823248"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yuling Fan","raw_affiliation_strings":["College of Informatics, Huazhong Agricultural University , Wuhan, 430070,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"College of Informatics, Huazhong Agricultural University , Wuhan, 430070,","institution_ids":["https://openalex.org/I204823248"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100669638","display_name":"Lin Li","orcid":"https://orcid.org/0000-0002-8519-5833","observed_orcids":["https://orcid.org/0000-0002-8519-5833"]},"institutions":[{"id":"https://openalex.org/I204823248","display_name":"Huazhong Agricultural University","ror":"https://ror.org/023b72294","country_code":"CN","type":"education","lineage":["https://openalex.org/I204823248"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Lin Li","raw_affiliation_strings":["College of Plant Science & Technology, Huazhong Agricultural University , Wuhan, 430070,"],"raw_orcid":"https://orcid.org/0000-0002-8519-5833","affiliations":[{"raw_affiliation_string":"College of Plant Science & Technology, Huazhong Agricultural University , Wuhan, 430070,","institution_ids":["https://openalex.org/I204823248"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5159050687","display_name":"Thuc Duy Le","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4405259444","display_name":"Adelaide University","ror":"https://ror.org/028g18b61","country_code":"AU","type":"education","lineage":["https://openalex.org/I4405259444"]},{"id":"https://openalex.org/I5681781","display_name":"The University of Adelaide","ror":"https://ror.org/00892tw58","country_code":"AU","type":"education","lineage":["https://openalex.org/I4405259444","https://openalex.org/I5681781"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"Thuc Duy Le","raw_affiliation_strings":["College of Engineering and Information Technology, Adelaide University , Adelaide, SA 5095,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"College of Engineering and Information Technology, Adelaide University , Adelaide, SA 5095,","institution_ids":["https://openalex.org/I4405259444","https://openalex.org/I5681781"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5158761530","display_name":"Xiaomei Li","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4405276010","display_name":"Commonwealth Bank of Australia (Australia)","ror":"https://ror.org/04pbqbn34","country_code":"AU","type":"company","lineage":["https://openalex.org/I4405276010"]}],"countries":["AU"],"is_corresponding":true,"raw_author_name":"Xiaomei Li","raw_affiliation_strings":["Business Banking, Commonwealth Bank , Sydney, NSW 2000,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Business Banking, Commonwealth Bank , Sydney, NSW 2000,","institution_ids":["https://openalex.org/I4405276010"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5065281913","display_name":"Debo Cheng","orcid":"https://orcid.org/0000-0002-0383-1462","observed_orcids":["https://orcid.org/0000-0002-0383-1462"]},"institutions":[{"id":"https://openalex.org/I20942203","display_name":"Hainan University","ror":"https://ror.org/03q648j11","country_code":"CN","type":"education","lineage":["https://openalex.org/I20942203"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Debo Cheng","raw_affiliation_strings":["School of Computer Science and Technology, Hainan University , Haikou, 570228,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Computer Science and Technology, Hainan University , Haikou, 570228,","institution_ids":["https://openalex.org/I20942203"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5049033206","display_name":"Zaiwen Feng","orcid":"https://orcid.org/0000-0003-1618-3553","observed_orcids":["https://orcid.org/0000-0003-1618-3553"]},"institutions":[{"id":"https://openalex.org/I204823248","display_name":"Huazhong Agricultural University","ror":"https://ror.org/023b72294","country_code":"CN","type":"education","lineage":["https://openalex.org/I204823248"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Zaiwen Feng","raw_affiliation_strings":["College of Informatics, Huazhong Agricultural University , Wuhan, 430070,","Hubei Key Laboratory of Agricultural Bioinformatics, Huazhong Agricultural University , Wuhan, 430070,"],"raw_orcid":"https://orcid.org/0000-0003-1618-3553","affiliations":[{"raw_affiliation_string":"College of Informatics, Huazhong Agricultural University , Wuhan, 430070,","institution_ids":["https://openalex.org/I204823248"]},{"raw_affiliation_string":"Hubei Key Laboratory of Agricultural Bioinformatics, Huazhong Agricultural University , Wuhan, 430070,","institution_ids":["https://openalex.org/I204823248"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":5,"corresponding_author_ids":["https://openalex.org/A5049033206","https://openalex.org/A5065281913","https://openalex.org/A5158761530"],"corresponding_institution_ids":["https://openalex.org/I204823248","https://openalex.org/I20942203","https://openalex.org/I4405276010"],"apc_list":{"value":3989,"currency":"USD","value_usd":3989},"apc_paid":{"value":3989,"currency":"USD","value_usd":3989},"fwci":0.0,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":{"value":0.72706671,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"42","issue":"10","first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10261","display_name":"Genetic Associations and Epidemiology","score":0.763700008392334,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10261","display_name":"Genetic Associations and Epidemiology","score":0.763700008392334,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11986","display_name":"Scientific Computing and Data Management","score":0.11990000307559967,"subfield":{"id":"https://openalex.org/subfields/1802","display_name":"Information Systems and Management"},"field":{"id":"https://openalex.org/fields/18","display_name":"Decision Sciences"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}},{"id":"https://openalex.org/T10887","display_name":"Bioinformatics and Genomic Networks","score":0.019099999219179153,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/mendelian-randomization","display_name":"Mendelian randomization","score":0.9959999918937683},{"id":"https://openalex.org/keywords/multi-agent-systems","display_name":"multi-agent systems","score":0.8980000019073486},{"id":"https://openalex.org/keywords/large-language-models","display_name":"large language models","score":0.9179999828338623},{"id":"https://openalex.org/keywords/code-repair","display_name":"code repair","score":0.6949999928474426},{"id":"https://openalex.org/keywords/reproducible-analysis-workflow","display_name":"reproducible analysis workflow","score":0.6079999804496765},{"id":"https://openalex.org/keywords/manuscript-writing","display_name":"manuscript preparation","score":0.6639999747276306},{"id":"https://openalex.org/keywords/causal-effect-estimation","display_name":"causal effect estimation","score":0.7269999980926514}],"concepts":[{"id":"https://openalex.org/C177212765","wikidata":"https://www.wikidata.org/wiki/Q627335","display_name":"Workflow","level":2,"score":0.8514000177383423},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.7688000202178955},{"id":"https://openalex.org/C2779901538","wikidata":"https://www.wikidata.org/wiki/Q6816584","display_name":"Mendelian randomization","level":5,"score":0.7221999764442444},{"id":"https://openalex.org/C185798385","wikidata":"https://www.wikidata.org/wiki/Q1161707","display_name":"Benchmark (surveying)","level":2,"score":0.6599000096321106},{"id":"https://openalex.org/C124101348","wikidata":"https://www.wikidata.org/wiki/Q172491","display_name":"Data mining","level":1,"score":0.491100013256073},{"id":"https://openalex.org/C119857082","wikidata":"https://www.wikidata.org/wiki/Q2539","display_name":"Machine learning","level":1,"score":0.41659998893737793},{"id":"https://openalex.org/C2777904410","wikidata":"https://www.wikidata.org/wiki/Q7397","display_name":"Software","level":2,"score":0.4066999852657318},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.39899998903274536},{"id":"https://openalex.org/C11671645","wikidata":"https://www.wikidata.org/wiki/Q5054567","display_name":"Causal model","level":2,"score":0.329800009727478},{"id":"https://openalex.org/C151201525","wikidata":"https://www.wikidata.org/wiki/Q177239","display_name":"Limit (mathematics)","level":2,"score":0.3264000117778778},{"id":"https://openalex.org/C106934330","wikidata":"https://www.wikidata.org/wiki/Q1971873","display_name":"Trait","level":2,"score":0.3230000138282776},{"id":"https://openalex.org/C43126263","wikidata":"https://www.wikidata.org/wiki/Q128751","display_name":"Source code","level":2,"score":0.3190000057220459},{"id":"https://openalex.org/C2987525970","wikidata":"https://www.wikidata.org/wiki/Q96374569","display_name":"Causal analysis","level":2,"score":0.29170000553131104},{"id":"https://openalex.org/C2984074130","wikidata":"https://www.wikidata.org/wiki/Q73539779","display_name":"R package","level":2,"score":0.2838999927043915},{"id":"https://openalex.org/C115086926","wikidata":"https://www.wikidata.org/wiki/Q17004651","display_name":"Causal reasoning","level":3,"score":0.27480000257492065},{"id":"https://openalex.org/C4554734","wikidata":"https://www.wikidata.org/wiki/Q593744","display_name":"Knowledge base","level":2,"score":0.266400009393692},{"id":"https://openalex.org/C158600405","wikidata":"https://www.wikidata.org/wiki/Q5054566","display_name":"Causal inference","level":2,"score":0.26030001044273376},{"id":"https://openalex.org/C115903868","wikidata":"https://www.wikidata.org/wiki/Q80993","display_name":"Software engineering","level":1,"score":0.257999986410141},{"id":"https://openalex.org/C2776505523","wikidata":"https://www.wikidata.org/wiki/Q4785468","display_name":"Plan (archaeology)","level":2,"score":0.25270000100135803}],"mesh":[{"descriptor_ui":"D000098342","descriptor_name":"Large Language Models","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D057182","descriptor_name":"Mendelian Randomization Analysis","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true}],"locations_count":3,"locations":[{"id":"doi:10.1093/bioinformatics/btag722","doi":"https://doi.org/10.1093/bioinformatics/btag722","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bioinformatics/btag722","pdf_url":"https://academic.oup.com/bioinformatics/advance-article-pdf/doi/10.1093/bioinformatics/btag722/72089679/btag722.pdf","source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["abdc-a","anvur-class-a","anvur-scientific","ccf-a","cwts-core","doaj","dongbi-b","doyens","jufo-3","ki-jl-2","medline","norway-2","oarl","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:13680005","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC13680005/","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC13680005/pdf/btag722.pdf","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"Text"},{"id":"pmid:42895113","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/42895113","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics (Oxford, England)","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.1093/bioinformatics/btag722","doi":"https://doi.org/10.1093/bioinformatics/btag722","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bioinformatics/btag722","pdf_url":"https://academic.oup.com/bioinformatics/advance-article-pdf/doi/10.1093/bioinformatics/btag722/72089679/btag722.pdf","source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["abdc-a","anvur-class-a","anvur-scientific","ccf-a","cwts-core","doaj","dongbi-b","doyens","jufo-3","ki-jl-2","medline","norway-2","oarl","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},"sustainable_development_goals":[],"study_designs":[],"awards":[{"id":"https://openalex.org/G540840432","display_name":null,"funder_award_id":"2023-YFF1000100","funder_id":"https://openalex.org/F4320335777","funder_display_name":"National Key Research and Development Program of China"}],"funders":[{"id":"https://openalex.org/F4320335777","display_name":"National Key Research and Development Program of China","ror":null}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W7222916622.pdf","grobid_xml":"https://content.openalex.org/works/W7222916622.grobid-xml"},"referenced_works_count":30,"referenced_works":["https://openalex.org/W1972696558","https://openalex.org/W2101746535","https://openalex.org/W2105161006","https://openalex.org/W2106036991","https://openalex.org/W2113699335","https://openalex.org/W2324862792","https://openalex.org/W2604218568","https://openalex.org/W2613603864","https://openalex.org/W2803072880","https://openalex.org/W2805983714","https://openalex.org/W2895486342","https://openalex.org/W2901303766","https://openalex.org/W2941271956","https://openalex.org/W2949543964","https://openalex.org/W3027865872","https://openalex.org/W3048245060","https://openalex.org/W4294553991","https://openalex.org/W4391136507","https://openalex.org/W4396723768","https://openalex.org/W4403099947","https://openalex.org/W4403785188","https://openalex.org/W4404330874","https://openalex.org/W4405599065","https://openalex.org/W4405766390","https://openalex.org/W4409228901","https://openalex.org/W4411720284","https://openalex.org/W4412709685","https://openalex.org/W4414827381","https://openalex.org/W7133224126","https://openalex.org/W7167845123"],"related_works":["https://openalex.org/W4409228901","https://openalex.org/W4416108792","https://openalex.org/W4415502886","https://openalex.org/W7203682992","https://openalex.org/W2909648768","https://openalex.org/W2125098987","https://openalex.org/W7099807180","https://openalex.org/W7213342257","https://openalex.org/W2806712690","https://openalex.org/W4414493504"],"abstract_inverted_index":{"MOTIVATION:":[0],"Understanding":[1],"disease-related":[2],"causal":[3,79,129,134],"mechanisms":[4],"is":[5],"essential":[6],"for":[7,165],"biomedical":[8,173],"research,":[9],"yet":[10],"the":[11,34,61,191],"practical":[12,163],"use":[13],"of":[14,40,66,113],"Mendelian":[15,100],"Randomization":[16,101],"(MR)":[17],"remains":[18],"constrained":[19],"by":[20],"fragmented":[21],"analytical":[22],"workflows":[23],"and":[24,37,63,71,84,110,131,139,149,168,182],"a":[25,56,88,98],"strong":[26],"dependence":[27],"on":[28,55],"specialized":[29],"expertise.":[30],"These":[31,156],"challenges":[32],"limit":[33],"efficient,":[35],"standardized,":[36,167],"reproducible":[38,169],"execution":[39],"end-to-end":[41,49],"MR":[42,51,107,114,170],"analyses.":[43],"RESULTS:":[44],"We":[45],"propose":[46],"MR-MAS,":[47],"an":[48],"automated":[50],"analysis":[52,115],"system":[53],"built":[54],"multi-agent":[57],"architecture.":[58],"MR-MAS":[59,95,121,160],"leverages":[60],"reasoning":[62],"coordination":[64],"capabilities":[65],"large":[67],"language":[68],"models":[69],"(LLMs)":[70],"integrates":[72],"external":[73],"tools":[74],"to":[75,105],"unify":[76],"data":[77,184],"acquisition,":[78],"effect":[80],"estimation,":[81],"results":[82,157],"interpretation,":[83],"manuscript":[85],"preparation":[86],"into":[87],"single":[89],"workflow,":[90],"thereby":[91],"reducing":[92],"manual":[93],"effort.":[94],"further":[96],"incorporates":[97],"structured":[99],"Knowledge":[102],"Base":[103],"(MRKB)":[104],"support":[106,164],"method":[108],"implementation":[109],"targeted":[111],"repair":[112],"code.":[116],"Across":[117],"diverse":[118],"test":[119],"scenarios,":[120],"demonstrated":[122],"stable":[123],"workflow":[124],"execution,":[125],"reproduced":[126],"several":[127],"literature-supported":[128],"signals,":[130],"maintained":[132],"consistent":[133],"estimates":[135],"across":[136],"repeated":[137],"runs":[138],"different":[140],"model":[141],"backends.":[142],"Additional":[143],"evaluations":[144],"showed":[145],"robust":[146],"trait":[147],"retrieval":[148],"improved":[150],"code-repair":[151],"performance":[152],"with":[153,190],"MRKB":[154],"guidance.":[155],"suggest":[158],"that":[159],"may":[161],"provide":[162],"scalable,":[166],"analyses":[171],"in":[172,194],"research.":[174],"AVAILABILITY":[175],"AND":[176],"IMPLEMENTATION:":[177],"The":[178],"source":[179],"code,":[180],"MRKB,":[181],"benchmark":[183],"are":[185],"freely":[186],"available":[187],"at":[188,198],"https://github.com/Zaiwen/MR-MAS,":[189],"version":[192],"used":[193],"this":[195],"study":[196],"archived":[197],"https://doi.org/10.5281/zenodo.20342636.":[199]},"counts_by_year":[],"updated_date":"2026-11-08T12:12:28.789561","created_date":"2026-10-20T00:00:00"}