{"id":"https://openalex.org/W7222903440","doi":"https://doi.org/10.7150/ijms.135665","title":"Reprogramming of Human Limbal Niche Progenitors","display_name":"Reprogramming of Human Limbal Niche Progenitors","publication_year":2026,"publication_date":"2026-09-24","ids":{"openalex":"https://openalex.org/W7222903440","doi":"https://doi.org/10.7150/ijms.135665","pmid":"https://pubmed.ncbi.nlm.nih.gov/42909366","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/13685034"},"language":"en","primary_location":{"id":"doi:10.7150/ijms.135665","doi":"https://doi.org/10.7150/ijms.135665","is_oa":true,"landing_page_url":"https://doi.org/10.7150/ijms.135665","pdf_url":"https://www.medsci.org/v23p3440.pdf","source":{"id":"https://openalex.org/S46225466","display_name":"International Journal of Medical Sciences","issn_l":"1449-1907","issn":["1449-1907"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-70","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310317973","host_organization_name":"Ivyspring International Publisher","host_organization_lineage":["https://openalex.org/P4310317973"],"host_organization_lineage_names":["Ivyspring International Publisher"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International Journal of Medical Sciences","raw_type":"journal-article"},"volume":null,"type":"review","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://www.medsci.org/v23p3440.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5159021620","display_name":"Xinghan Guo","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210160344","display_name":"Tongji Hospital","ror":"https://ror.org/04xy45965","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210160344"]},{"id":"https://openalex.org/I47720641","display_name":"Huazhong University of Science and Technology","ror":"https://ror.org/00p991c53","country_code":"CN","type":"education","lineage":["https://openalex.org/I47720641"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Xinghan Guo","raw_affiliation_strings":["Department of Ophthalmology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China","Hubei Key Laboratory of Otolaryngologic and Ophthalmic Diseases, Wuhan, 430000, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Ophthalmology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China","institution_ids":["https://openalex.org/I4210160344","https://openalex.org/I47720641"]},{"raw_affiliation_string":"Hubei Key Laboratory of Otolaryngologic and Ophthalmic Diseases, Wuhan, 430000, China","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5159015615","display_name":"Wei Wang","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210160344","display_name":"Tongji Hospital","ror":"https://ror.org/04xy45965","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210160344"]},{"id":"https://openalex.org/I47720641","display_name":"Huazhong University of Science and Technology","ror":"https://ror.org/00p991c53","country_code":"CN","type":"education","lineage":["https://openalex.org/I47720641"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Wei Wang","raw_affiliation_strings":["Department of Ophthalmology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China","Hubei Key Laboratory of Otolaryngologic and Ophthalmic Diseases, Wuhan, 430000, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Ophthalmology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China","institution_ids":["https://openalex.org/I4210160344","https://openalex.org/I47720641"]},{"raw_affiliation_string":"Hubei Key Laboratory of Otolaryngologic and Ophthalmic Diseases, Wuhan, 430000, China","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5089500554","display_name":"Allison Wilde","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Allison Wilde","raw_affiliation_strings":["BioTissue, Miami, FL, 33126 USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"BioTissue, Miami, FL, 33126 USA","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5130022622","display_name":"Yingting Zhu","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Yingting Zhu","raw_affiliation_strings":["BioTissue, Miami, FL, 33126 USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"BioTissue, Miami, FL, 33126 USA","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5051406100","display_name":"\u674e\u8d35\u521a","orcid":"https://orcid.org/0000-0002-1943-6600","observed_orcids":["https://orcid.org/0000-0002-1943-6600"]},"institutions":[{"id":"https://openalex.org/I4210160344","display_name":"Tongji Hospital","ror":"https://ror.org/04xy45965","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210160344"]},{"id":"https://openalex.org/I47720641","display_name":"Huazhong University of Science and Technology","ror":"https://ror.org/00p991c53","country_code":"CN","type":"education","lineage":["https://openalex.org/I47720641"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Guigang Li","raw_affiliation_strings":["Department of Ophthalmology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China","Hubei Key Laboratory of Otolaryngologic and Ophthalmic Diseases, Wuhan, 430000, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Ophthalmology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China","institution_ids":["https://openalex.org/I4210160344","https://openalex.org/I47720641"]},{"raw_affiliation_string":"Hubei Key Laboratory of Otolaryngologic and Ophthalmic Diseases, Wuhan, 430000, China","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5051406100","https://openalex.org/A5130022622"],"corresponding_institution_ids":["https://openalex.org/I4210160344","https://openalex.org/I47720641"],"apc_list":{"value":2000,"currency":"AUD","value_usd":1337},"apc_paid":{"value":2000,"currency":"AUD","value_usd":1337},"fwci":0.0,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":{"value":0.62223886,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"23","issue":"11","first_page":"3440","last_page":"3452"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11828","display_name":"Corneal Surgery and Treatments","score":0.861299991607666,"subfield":{"id":"https://openalex.org/subfields/2731","display_name":"Ophthalmology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11828","display_name":"Corneal Surgery and Treatments","score":0.861299991607666,"subfield":{"id":"https://openalex.org/subfields/2731","display_name":"Ophthalmology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10505","display_name":"Pluripotent Stem Cells Research","score":0.06679999828338623,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10176","display_name":"Mesenchymal stem cell research","score":0.050599999725818634,"subfield":{"id":"https://openalex.org/subfields/1307","display_name":"Cell Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/limbal-stem-cell-deficiency","display_name":"limbal stem cell deficiency","score":0.824999988079071},{"id":"https://openalex.org/keywords/adult-stem-cells","display_name":"adult stem cells","score":0.7429999709129333},{"id":"https://openalex.org/keywords/stem-cell-reprogramming","display_name":"stem cell reprogramming","score":0.7860000133514404},{"id":"https://openalex.org/keywords/cell-therapy","display_name":"cell therapy","score":0.6349999904632568},{"id":"https://openalex.org/keywords/eye-diseases","display_name":"eye diseases","score":0.6629999876022339},{"id":"https://openalex.org/keywords/stem-cell-differentiation","display_name":"stem cell differentiation","score":0.5680000185966492},{"id":"https://openalex.org/keywords/angiogenesis","display_name":"angiogenesis","score":0.4950000047683716},{"id":"https://openalex.org/keywords/stem-cell-maintenance","display_name":"stem cell maintenance","score":0.5049999952316284},{"id":"https://openalex.org/keywords/corneal-regeneration","display_name":"corneal regeneration","score":0.6899999976158142}],"concepts":[{"id":"https://openalex.org/C28328180","wikidata":"https://www.wikidata.org/wiki/Q48196","display_name":"Stem cell","level":2,"score":0.7721999883651733},{"id":"https://openalex.org/C77255625","wikidata":"https://www.wikidata.org/wiki/Q402093","display_name":"Reprogramming","level":3,"score":0.7203999757766724},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.7020999789237976},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.6969000101089478},{"id":"https://openalex.org/C201750760","wikidata":"https://www.wikidata.org/wiki/Q1896218","display_name":"Progenitor cell","level":3,"score":0.6700999736785889},{"id":"https://openalex.org/C145103041","wikidata":"https://www.wikidata.org/wiki/Q1151519","display_name":"Embryonic stem cell","level":3,"score":0.6640999913215637},{"id":"https://openalex.org/C164794517","wikidata":"https://www.wikidata.org/wiki/Q16729831","display_name":"Stem cell niche","level":4,"score":0.5946000218391418},{"id":"https://openalex.org/C153991713","wikidata":"https://www.wikidata.org/wiki/Q17142856","display_name":"Niche","level":2,"score":0.5194000005722046},{"id":"https://openalex.org/C16930146","wikidata":"https://www.wikidata.org/wiki/Q4381253","display_name":"Stromal cell","level":2,"score":0.4966000020503998},{"id":"https://openalex.org/C20875687","wikidata":"https://www.wikidata.org/wiki/Q2642600","display_name":"Adult stem cell","level":4,"score":0.49639999866485596},{"id":"https://openalex.org/C123012128","wikidata":"https://www.wikidata.org/wiki/Q5376430","display_name":"Endothelial stem cell","level":3,"score":0.47920000553131104},{"id":"https://openalex.org/C18414845","wikidata":"https://www.wikidata.org/wiki/Q15107837","display_name":"Induced stem cells","level":5,"score":0.4526999890804291},{"id":"https://openalex.org/C171056886","wikidata":"https://www.wikidata.org/wiki/Q193119","display_name":"Regeneration (biology)","level":2,"score":0.44279998540878296},{"id":"https://openalex.org/C198826908","wikidata":"https://www.wikidata.org/wiki/Q1922379","display_name":"Mesenchymal stem cell","level":2,"score":0.41749998927116394},{"id":"https://openalex.org/C107459253","wikidata":"https://www.wikidata.org/wiki/Q674925","display_name":"Induced pluripotent stem cell","level":4,"score":0.4106999933719635},{"id":"https://openalex.org/C2780394083","wikidata":"https://www.wikidata.org/wiki/Q539568","display_name":"Angiogenesis","level":2,"score":0.39340001344680786},{"id":"https://openalex.org/C10882517","wikidata":"https://www.wikidata.org/wiki/Q15268054","display_name":"Cell therapy","level":3,"score":0.392300009727478},{"id":"https://openalex.org/C1491633281","wikidata":"https://www.wikidata.org/wiki/Q7868","display_name":"Cell","level":2,"score":0.3862000107765198},{"id":"https://openalex.org/C148738053","wikidata":"https://www.wikidata.org/wiki/Q210861","display_name":"Cellular differentiation","level":3,"score":0.3828999996185303},{"id":"https://openalex.org/C2779389132","wikidata":"https://www.wikidata.org/wiki/Q1533033","display_name":"Stem-cell therapy","level":3,"score":0.36059999465942383},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.3578000068664551},{"id":"https://openalex.org/C202438428","wikidata":"https://www.wikidata.org/wiki/Q1939923","display_name":"Somatic cell nuclear transfer","level":5,"score":0.31119999289512634},{"id":"https://openalex.org/C189014844","wikidata":"https://www.wikidata.org/wiki/Q189118","display_name":"Cell type","level":3,"score":0.27399998903274536},{"id":"https://openalex.org/C13685319","wikidata":"https://www.wikidata.org/wiki/Q7607302","display_name":"Stem cell transplantation for articular cartilage repair","level":5,"score":0.27070000767707825},{"id":"https://openalex.org/C2777117487","wikidata":"https://www.wikidata.org/wiki/Q18811569","display_name":"Directed differentiation","level":5,"score":0.260699987411499},{"id":"https://openalex.org/C143441281","wikidata":"https://www.wikidata.org/wiki/Q5133858","display_name":"Clinical uses of mesenchymal stem cells","level":5,"score":0.25609999895095825},{"id":"https://openalex.org/C15729860","wikidata":"https://www.wikidata.org/wiki/Q2329919","display_name":"Progenitor","level":4,"score":0.2522999942302704}],"mesh":[{"descriptor_ui":"D000092423","descriptor_name":"Limbal Stem Cell Deficiency","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":false},{"descriptor_ui":"D000093282","descriptor_name":"Limbal Stem Cells","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002454","descriptor_name":"Cell Differentiation","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016850","descriptor_name":"Limbus Corneae","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":true},{"descriptor_ui":"D033581","descriptor_name":"Stem Cell Transplantation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D053595","descriptor_name":"Embryonic Stem Cells","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":false},{"descriptor_ui":"D053687","descriptor_name":"Adult Stem Cells","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":false},{"descriptor_ui":"D055153","descriptor_name":"Stem Cell Niche","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D055153","descriptor_name":"Stem Cell Niche","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D065150","descriptor_name":"Cellular Reprogramming","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true}],"locations_count":3,"locations":[{"id":"doi:10.7150/ijms.135665","doi":"https://doi.org/10.7150/ijms.135665","is_oa":true,"landing_page_url":"https://doi.org/10.7150/ijms.135665","pdf_url":"https://www.medsci.org/v23p3440.pdf","source":{"id":"https://openalex.org/S46225466","display_name":"International Journal of Medical Sciences","issn_l":"1449-1907","issn":["1449-1907"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-70","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310317973","host_organization_name":"Ivyspring International Publisher","host_organization_lineage":["https://openalex.org/P4310317973"],"host_organization_lineage_names":["Ivyspring International Publisher"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International Journal of Medical Sciences","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:13685034","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC13685034/","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC13685034/pdf/ijmsv23p3440.pdf","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Int J Med Sci","raw_type":"Text"},{"id":"pmid:42909366","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/42909366","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International journal of medical sciences","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.7150/ijms.135665","doi":"https://doi.org/10.7150/ijms.135665","is_oa":true,"landing_page_url":"https://doi.org/10.7150/ijms.135665","pdf_url":"https://www.medsci.org/v23p3440.pdf","source":{"id":"https://openalex.org/S46225466","display_name":"International Journal of Medical Sciences","issn_l":"1449-1907","issn":["1449-1907"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-70","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310317973","host_organization_name":"Ivyspring International Publisher","host_organization_lineage":["https://openalex.org/P4310317973"],"host_organization_lineage_names":["Ivyspring International Publisher"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International Journal of Medical Sciences","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.9391000270843506}],"study_designs":[],"awards":[{"id":"https://openalex.org/G2804751791","display_name":null,"funder_award_id":"82471050","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"}],"funders":[{"id":"https://openalex.org/F4320321001","display_name":"National Natural Science Foundation of China","ror":"https://ror.org/01h0zpd94"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W7222903440.pdf","grobid_xml":"https://content.openalex.org/works/W7222903440.grobid-xml"},"referenced_works_count":1,"referenced_works":["https://openalex.org/W4387968200"],"related_works":["https://openalex.org/W2801892506","https://openalex.org/W3135011529","https://openalex.org/W2011540058","https://openalex.org/W2013899958","https://openalex.org/W2766297399","https://openalex.org/W3209876574","https://openalex.org/W2005501677","https://openalex.org/W1967479683","https://openalex.org/W2554576720","https://openalex.org/W2016492649"],"abstract_inverted_index":{"Limbal":[0],"niche":[1,110],"cells":[2,40,60,78],"(LNCs)":[3],"possess":[4],"embryonic":[5],"stem":[6,55,90,96,134,148],"cell":[7,91,97,135,149],"(ESC)":[8],"characteristics,":[9,20],"expressing":[10,21,31],"ESC":[11],"markers":[12,23,33],"such":[13,24,34,73,93],"as":[14,25,35,94],"Sox2,":[15],"Nanog,":[16],"and":[17,27,47,65,75,121],"Oct4;":[18],"stromal":[19],"neurocrest":[22],"CD90;":[26],"have":[28],"angiogenic":[29],"potential":[30],"angiogenesis":[32],"CD34.":[36],"In":[37],"addition,":[38],"these":[39,59],"can":[41,79],"be":[42,62,80],"induced":[43],"into":[44],"adipocytes,":[45],"chondrocytes,":[46],"osteocytes,":[48],"indicating":[49],"that":[50],"they":[51],"are":[52,70],"valuable":[53],"adult":[54,118],"cells.":[56],"However,":[57],"how":[58,76],"may":[61,142],"appropriately":[63],"passaged":[64],"maintained,":[66],"what":[67],"signaling":[68],"pathways":[69],"necessary":[71],"for":[72,82,128,147,151],"regeneration,":[74],"the":[77,83,104,115],"used":[81],"treatment":[84],"of":[85,117],"various":[86,129],"diseases":[87,131,155],"caused":[88],"by":[89],"deficiency,":[92,98],"limbal":[95,109,119],"remain":[99],"unclear.":[100],"Herein,":[101],"we":[102],"summarize":[103],"most":[105],"recent":[106],"advances":[107],"in":[108],"research,":[111],"with":[112],"emphasis":[113],"on":[114],"regeneration":[116],"progenitors":[120],"their":[122],"mechanisms,":[123],"to":[124,133],"promote":[125],"cell-based":[126],"therapy":[127,150],"eye":[130],"due":[132],"deficiency":[136],"or":[137],"malfunction.":[138],"Such":[139],"a":[140,145],"strategy":[141],"also":[143],"provide":[144],"platform":[146],"other":[152],"similar":[153],"human":[154],"worldwide.":[156]},"counts_by_year":[],"updated_date":"2026-11-08T12:12:28.789561","created_date":"2026-10-19T00:00:00"}