{"id":"https://openalex.org/W7222886979","doi":"https://doi.org/10.64898/2026.10.15.757554","title":"Structural topology shapes regional roles in neuronal avalanche initiation and termination","display_name":"Structural topology shapes regional roles in neuronal avalanche initiation and termination","publication_year":2026,"publication_date":"2026-10-16","ids":{"openalex":"https://openalex.org/W7222886979","doi":"https://doi.org/10.64898/2026.10.15.757554"},"language":"en","primary_location":{"id":"doi:10.64898/2026.10.15.757554","doi":"https://doi.org/10.64898/2026.10.15.757554","is_oa":true,"landing_page_url":"https://doi.org/10.64898/2026.10.15.757554","pdf_url":"https://www.biorxiv.org/content/biorxiv/early/2026/10/16/2026.10.15.757554.full.pdf","source":{"id":"https://openalex.org/S4306402567","display_name":"bioRxiv (Cold Spring Harbor Laboratory)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I2750212522","host_organization_name":"Cold Spring Harbor Laboratory","host_organization_lineage":["https://openalex.org/I2750212522"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"bioRxiv","raw_type":"posted-content"},"volume":null,"type":"preprint","is_traditional":true,"indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.biorxiv.org/content/biorxiv/early/2026/10/16/2026.10.15.757554.full.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5153484937","display_name":"Mario De Luca","orcid":"https://orcid.org/0009-0002-8285-1177","observed_orcids":["https://orcid.org/0009-0002-8285-1177"]},"institutions":[{"id":"https://openalex.org/I183638586","display_name":"Parthenope University of Naples","ror":"https://ror.org/05pcv4v03","country_code":"IT","type":"education","lineage":["https://openalex.org/I183638586"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Mario De Luca","raw_affiliation_strings":["Department of Medical, Motor and Wellness Sciences, University of Naples \u201cParthenope\u201d, 80133 Napoli, Italy"],"raw_orcid":"https://orcid.org/0009-0002-8285-1177","affiliations":[{"raw_affiliation_string":"Department of Medical, Motor and Wellness Sciences, University of Naples \u201cParthenope\u201d, 80133 Napoli, Italy","institution_ids":["https://openalex.org/I183638586"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5000007331","display_name":"Matteo Demuru","orcid":"https://orcid.org/0000-0002-4336-2170","observed_orcids":["https://orcid.org/0000-0002-4336-2170"]},"institutions":[{"id":"https://openalex.org/I183638586","display_name":"Parthenope University of Naples","ror":"https://ror.org/05pcv4v03","country_code":"IT","type":"education","lineage":["https://openalex.org/I183638586"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Matteo Demuru","raw_affiliation_strings":["Department of Medical, Motor and Wellness Sciences, University of Naples \u201cParthenope\u201d, 80133 Napoli, Italy"],"raw_orcid":"https://orcid.org/0000-0002-4336-2170","affiliations":[{"raw_affiliation_string":"Department of Medical, Motor and Wellness Sciences, University of Naples \u201cParthenope\u201d, 80133 Napoli, Italy","institution_ids":["https://openalex.org/I183638586"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5029491660","display_name":"Emahnuel Troisi Lopez","orcid":"https://orcid.org/0000-0002-0220-2672","observed_orcids":["https://orcid.org/0000-0002-0220-2672"]},"institutions":[{"id":"https://openalex.org/I4210125310","display_name":"Pegaso University","ror":"https://ror.org/03cxwg632","country_code":"IT","type":"education","lineage":["https://openalex.org/I4210125310"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Emahnuel Troisi Lopez","raw_affiliation_strings":["Department of Education and Sport Sciences, Pegaso Telematic University, 80143, Naples, Italy"],"raw_orcid":"https://orcid.org/0000-0002-0220-2672","affiliations":[{"raw_affiliation_string":"Department of Education and Sport Sciences, Pegaso Telematic University, 80143, Naples, Italy","institution_ids":["https://openalex.org/I4210125310"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5121552936","display_name":"Enrica Gallo","orcid":"https://orcid.org/0009-0003-1420-7416","observed_orcids":["https://orcid.org/0009-0003-1420-7416","https://orcid.org/0009-0005-4633-9397"]},"institutions":[{"id":"https://openalex.org/I183638586","display_name":"Parthenope University of Naples","ror":"https://ror.org/05pcv4v03","country_code":"IT","type":"education","lineage":["https://openalex.org/I183638586"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Enrica Gallo","raw_affiliation_strings":["Department of Medical, Motor and Wellness Sciences, University of Naples \u201cParthenope\u201d, 80133 Napoli, Italy"],"raw_orcid":"https://orcid.org/0009-0003-1420-7416","affiliations":[{"raw_affiliation_string":"Department of Medical, Motor and Wellness Sciences, University of Naples \u201cParthenope\u201d, 80133 Napoli, Italy","institution_ids":["https://openalex.org/I183638586"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5119219570","display_name":"Gianmarco Cafaro","orcid":"https://orcid.org/0009-0002-4354-1328","observed_orcids":["https://orcid.org/0009-0002-4354-1328"]},"institutions":[{"id":"https://openalex.org/I131729948","display_name":"University of Salerno","ror":"https://ror.org/0192m2k53","country_code":"IT","type":"education","lineage":["https://openalex.org/I131729948"]},{"id":"https://openalex.org/I4210152066","display_name":"IRCCS Eugenio Medea","ror":"https://ror.org/05ynr3m75","country_code":"IT","type":"facility","lineage":["https://openalex.org/I4210152066","https://openalex.org/I4210153126"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Gianmarco Cafaro","raw_affiliation_strings":["Department of Physics \u201cE.R. Caianiello\u201d, University of Salerno, Fisciano, Italy","Epilepsy and Clinical Neurophysiology Unit, IRCCS Eugenio Medea, Conegliano, Italy"],"raw_orcid":"https://orcid.org/0009-0002-4354-1328","affiliations":[{"raw_affiliation_string":"Department of Physics \u201cE.R. Caianiello\u201d, University of Salerno, Fisciano, Italy","institution_ids":["https://openalex.org/I131729948"]},{"raw_affiliation_string":"Epilepsy and Clinical Neurophysiology Unit, IRCCS Eugenio Medea, Conegliano, Italy","institution_ids":["https://openalex.org/I4210152066"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5058747902","display_name":"Gian Marco Duma","orcid":"https://orcid.org/0000-0002-0778-3920","observed_orcids":["https://orcid.org/0000-0002-0778-3920"]},"institutions":[{"id":"https://openalex.org/I4210152066","display_name":"IRCCS Eugenio Medea","ror":"https://ror.org/05ynr3m75","country_code":"IT","type":"facility","lineage":["https://openalex.org/I4210152066","https://openalex.org/I4210153126"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Gian Marco Duma","raw_affiliation_strings":["Epilepsy and Clinical Neurophysiology Unit, IRCCS Eugenio Medea, Conegliano, Italy"],"raw_orcid":"https://orcid.org/0000-0002-0778-3920","affiliations":[{"raw_affiliation_string":"Epilepsy and Clinical Neurophysiology Unit, IRCCS Eugenio Medea, Conegliano, Italy","institution_ids":["https://openalex.org/I4210152066"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5018882458","display_name":"Damien Depannemaecker","orcid":"https://orcid.org/0000-0003-1936-4560","observed_orcids":["https://orcid.org/0000-0003-1936-4560"]},"institutions":[{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I21491767","display_name":"Aix-Marseille Universit\u00e9","ror":"https://ror.org/035xkbk20","country_code":"FR","type":"education","lineage":["https://openalex.org/I21491767"]},{"id":"https://openalex.org/I4210110495","display_name":"Institut de Neurosciences des Syst\u00e8mes","ror":"https://ror.org/019kqby73","country_code":"FR","type":"facility","lineage":["https://openalex.org/I154526488","https://openalex.org/I21491767","https://openalex.org/I4210110495"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Damien Depannemaecker","raw_affiliation_strings":["Aix-Marseille Univ, INSERM, INS, Institut de Neurosciences des Syst\u00e8mes, Marseille, France"],"raw_orcid":"https://orcid.org/0000-0003-1936-4560","affiliations":[{"raw_affiliation_string":"Aix-Marseille Univ, INSERM, INS, Institut de Neurosciences des Syst\u00e8mes, Marseille, France","institution_ids":["https://openalex.org/I154526488","https://openalex.org/I21491767","https://openalex.org/I4210110495"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5119547316","display_name":"Gabriele Casagrande","orcid":"https://orcid.org/0009-0007-3037-3923","observed_orcids":["https://orcid.org/0009-0007-3037-3923"]},"institutions":[{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I21491767","display_name":"Aix-Marseille Universit\u00e9","ror":"https://ror.org/035xkbk20","country_code":"FR","type":"education","lineage":["https://openalex.org/I21491767"]},{"id":"https://openalex.org/I4210110495","display_name":"Institut de Neurosciences des Syst\u00e8mes","ror":"https://ror.org/019kqby73","country_code":"FR","type":"facility","lineage":["https://openalex.org/I154526488","https://openalex.org/I21491767","https://openalex.org/I4210110495"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Gabriele Casagrande","raw_affiliation_strings":["Aix-Marseille Univ, INSERM, INS, Institut de Neurosciences des Syst\u00e8mes, Marseille, France"],"raw_orcid":"https://orcid.org/0009-0007-3037-3923","affiliations":[{"raw_affiliation_string":"Aix-Marseille Univ, INSERM, INS, Institut de Neurosciences des Syst\u00e8mes, Marseille, France","institution_ids":["https://openalex.org/I154526488","https://openalex.org/I21491767","https://openalex.org/I4210110495"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5058357386","display_name":"Mario Quarantelli","orcid":"https://orcid.org/0000-0001-7836-454X","observed_orcids":["https://orcid.org/0000-0001-7836-454X","https://orcid.org/0000-0003-2341-0814"]},"institutions":[{"id":"https://openalex.org/I4210137074","display_name":"Institute of Biostructure and Bioimaging","ror":"https://ror.org/03rqtqb02","country_code":"IT","type":"facility","lineage":["https://openalex.org/I4210137074","https://openalex.org/I4210155236"]},{"id":"https://openalex.org/I4210155236","display_name":"National Research Council","ror":"https://ror.org/04zaypm56","country_code":"IT","type":"nonprofit","lineage":["https://openalex.org/I4210155236"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Mario Quarantelli","raw_affiliation_strings":["Institute of Biostructures and Bioimaging, Italian National Research Council, Naples, Italy"],"raw_orcid":"https://orcid.org/0000-0001-7836-454X","affiliations":[{"raw_affiliation_string":"Institute of Biostructures and Bioimaging, Italian National Research Council, Naples, Italy","institution_ids":["https://openalex.org/I4210137074","https://openalex.org/I4210155236"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5005963473","display_name":"C. Granata","orcid":"https://orcid.org/0000-0001-5724-0994","observed_orcids":["https://orcid.org/0000-0001-5724-0994"]},"institutions":[{"id":"https://openalex.org/I4210091512","display_name":"Institute of Applied Science and Intelligent Systems","ror":"https://ror.org/00be3zh53","country_code":"IT","type":"facility","lineage":["https://openalex.org/I4210091512","https://openalex.org/I4210155236"]},{"id":"https://openalex.org/I4210155236","display_name":"National Research Council","ror":"https://ror.org/04zaypm56","country_code":"IT","type":"nonprofit","lineage":["https://openalex.org/I4210155236"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Carmine Granata","raw_affiliation_strings":["Institute of Applied Sciences and Intelligent Systems of National Research Council, Pozzuoli, Italy"],"raw_orcid":"https://orcid.org/0000-0001-5724-0994","affiliations":[{"raw_affiliation_string":"Institute of Applied Sciences and Intelligent Systems of National Research Council, Pozzuoli, Italy","institution_ids":["https://openalex.org/I4210091512","https://openalex.org/I4210155236"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5075309221","display_name":"Giuseppe Sorrentino","orcid":"https://orcid.org/0000-0003-0800-2433","observed_orcids":["https://orcid.org/0000-0003-0800-2433","https://orcid.org/0000-0002-5948-1414"]},"institutions":[{"id":"https://openalex.org/I4210091512","display_name":"Institute of Applied Science and Intelligent Systems","ror":"https://ror.org/00be3zh53","country_code":"IT","type":"facility","lineage":["https://openalex.org/I4210091512","https://openalex.org/I4210155236"]},{"id":"https://openalex.org/I4210155236","display_name":"National Research Council","ror":"https://ror.org/04zaypm56","country_code":"IT","type":"nonprofit","lineage":["https://openalex.org/I4210155236"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Giuseppe Sorrentino","raw_affiliation_strings":["Institute of Applied Sciences and Intelligent Systems of National Research Council, Pozzuoli, Italy"],"raw_orcid":"https://orcid.org/0000-0003-0800-2433","affiliations":[{"raw_affiliation_string":"Institute of Applied Sciences and Intelligent Systems of National Research Council, Pozzuoli, Italy","institution_ids":["https://openalex.org/I4210091512","https://openalex.org/I4210155236"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5011664348","display_name":"Pierpaolo Sorrentino","orcid":"https://orcid.org/0000-0002-9556-9800","observed_orcids":["https://orcid.org/0000-0002-9556-9800"]},"institutions":[{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I183638586","display_name":"Parthenope University of Naples","ror":"https://ror.org/05pcv4v03","country_code":"IT","type":"education","lineage":["https://openalex.org/I183638586"]},{"id":"https://openalex.org/I21491767","display_name":"Aix-Marseille Universit\u00e9","ror":"https://ror.org/035xkbk20","country_code":"FR","type":"education","lineage":["https://openalex.org/I21491767"]},{"id":"https://openalex.org/I4210110495","display_name":"Institut de Neurosciences des Syst\u00e8mes","ror":"https://ror.org/019kqby73","country_code":"FR","type":"facility","lineage":["https://openalex.org/I154526488","https://openalex.org/I21491767","https://openalex.org/I4210110495"]}],"countries":["FR","IT"],"is_corresponding":true,"raw_author_name":"Pierpaolo Sorrentino","raw_affiliation_strings":["Aix-Marseille Univ, INSERM, INS, Institut de Neurosciences des Syst\u00e8mes, Marseille, France","Department of Medical, Motor and Wellness Sciences, University of Naples \u201cParthenope\u201d, 80133 Napoli, Italy"],"raw_orcid":"https://orcid.org/0000-0002-9556-9800","affiliations":[{"raw_affiliation_string":"Aix-Marseille Univ, INSERM, INS, Institut de Neurosciences des Syst\u00e8mes, Marseille, France","institution_ids":["https://openalex.org/I154526488","https://openalex.org/I21491767","https://openalex.org/I4210110495"]},{"raw_affiliation_string":"Department of Medical, Motor and Wellness Sciences, University of Naples \u201cParthenope\u201d, 80133 Napoli, Italy","institution_ids":["https://openalex.org/I183638586"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5038073059","display_name":"Marianna Angiolelli","orcid":"https://orcid.org/0000-0001-9717-0572","observed_orcids":["https://orcid.org/0000-0001-9717-0572"]},"institutions":[{"id":"https://openalex.org/I183638586","display_name":"Parthenope University of Naples","ror":"https://ror.org/05pcv4v03","country_code":"IT","type":"education","lineage":["https://openalex.org/I183638586"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Marianna Angiolelli","raw_affiliation_strings":["Department of Medical, Motor and Wellness Sciences, University of Naples \u201cParthenope\u201d, 80133 Napoli, Italy"],"raw_orcid":"https://orcid.org/0000-0001-9717-0572","affiliations":[{"raw_affiliation_string":"Department of Medical, Motor and Wellness Sciences, University of Naples \u201cParthenope\u201d, 80133 Napoli, Italy","institution_ids":["https://openalex.org/I183638586"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":10,"corresponding_author_ids":["https://openalex.org/A5011664348"],"corresponding_institution_ids":["https://openalex.org/I154526488","https://openalex.org/I183638586","https://openalex.org/I21491767","https://openalex.org/I4210110495"],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10241","display_name":"Functional Brain Connectivity Studies","score":0.9340999722480774,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10241","display_name":"Functional Brain Connectivity Studies","score":0.9340999722480774,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10581","display_name":"Neural dynamics and brain function","score":0.056299999356269836,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11304","display_name":"Advanced Neuroimaging Techniques and Applications","score":0.004100000020116568,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/neuronal-avalanches","display_name":"neuronal avalanches","score":0.9990000128746033},{"id":"https://openalex.org/keywords/structural-connectome","display_name":"structural connectome","score":0.7070000171661377},{"id":"https://openalex.org/keywords/white-matter-tracts","display_name":"white matter tracts","score":0.875},{"id":"https://openalex.org/keywords/avalanche-initiation","display_name":"avalanche initiation","score":0.6079999804496765},{"id":"https://openalex.org/keywords/cortical-dynamics","display_name":"cortical dynamics","score":0.4909999966621399},{"id":"https://openalex.org/keywords/structure-function-coupling","display_name":"structure-function coupling","score":0.8399999737739563},{"id":"https://openalex.org/keywords/resting-state-brain-activity","display_name":"resting-state brain activity","score":0.7580000162124634}],"concepts":[{"id":"https://openalex.org/C84787856","wikidata":"https://www.wikidata.org/wiki/Q3076659","display_name":"Tractography","level":4,"score":0.7189000248908997},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.6554999947547913},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.5210999846458435},{"id":"https://openalex.org/C131584629","wikidata":"https://www.wikidata.org/wiki/Q4308705","display_name":"Coupling (piping)","level":2,"score":0.4961000084877014},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.4657000005245209},{"id":"https://openalex.org/C184720557","wikidata":"https://www.wikidata.org/wiki/Q7825049","display_name":"Topology (electrical circuits)","level":2,"score":0.45980000495910645},{"id":"https://openalex.org/C2780799671","wikidata":"https://www.wikidata.org/wiki/Q17087362","display_name":"Transient (computer programming)","level":2,"score":0.4359000027179718},{"id":"https://openalex.org/C2781192897","wikidata":"https://www.wikidata.org/wiki/Q822050","display_name":"White matter","level":3,"score":0.4350999891757965},{"id":"https://openalex.org/C45715564","wikidata":"https://www.wikidata.org/wiki/Q1292103","display_name":"Connectome","level":3,"score":0.4260999858379364},{"id":"https://openalex.org/C556910895","wikidata":"https://www.wikidata.org/wiki/Q384188","display_name":"Magnetoencephalography","level":3,"score":0.3806999921798706},{"id":"https://openalex.org/C2777670902","wikidata":"https://www.wikidata.org/wiki/Q492038","display_name":"Human brain","level":2,"score":0.37599998712539673},{"id":"https://openalex.org/C149550507","wikidata":"https://www.wikidata.org/wiki/Q899360","display_name":"Diffusion MRI","level":3,"score":0.375},{"id":"https://openalex.org/C199845137","wikidata":"https://www.wikidata.org/wiki/Q145490","display_name":"Network topology","level":2,"score":0.3723999857902527},{"id":"https://openalex.org/C152478114","wikidata":"https://www.wikidata.org/wiki/Q660910","display_name":"Neurophysiology","level":2,"score":0.37229999899864197},{"id":"https://openalex.org/C2780196419","wikidata":"https://www.wikidata.org/wiki/Q1762173","display_name":"Nerve net","level":2,"score":0.3328000009059906},{"id":"https://openalex.org/C21308566","wikidata":"https://www.wikidata.org/wiki/Q7169365","display_name":"Permutation (music)","level":2,"score":0.3043000102043152},{"id":"https://openalex.org/C2779478453","wikidata":"https://www.wikidata.org/wiki/Q6889748","display_name":"Modularity (biology)","level":2,"score":0.29750001430511475},{"id":"https://openalex.org/C3018011982","wikidata":"https://www.wikidata.org/wiki/Q7316120","display_name":"Functional connectivity","level":2,"score":0.289000004529953},{"id":"https://openalex.org/C53645450","wikidata":"https://www.wikidata.org/wiki/Q907093","display_name":"Scaffold protein","level":3,"score":0.2867000102996826},{"id":"https://openalex.org/C117220453","wikidata":"https://www.wikidata.org/wiki/Q5172842","display_name":"Correlation","level":2,"score":0.2782999873161316},{"id":"https://openalex.org/C150060386","wikidata":"https://www.wikidata.org/wiki/Q7574054","display_name":"Spatial correlation","level":2,"score":0.27730000019073486},{"id":"https://openalex.org/C97820695","wikidata":"https://www.wikidata.org/wiki/Q387749","display_name":"Human Connectome Project","level":3,"score":0.2667999863624573},{"id":"https://openalex.org/C2779226451","wikidata":"https://www.wikidata.org/wiki/Q903809","display_name":"Functional magnetic resonance imaging","level":2,"score":0.2612000107765198},{"id":"https://openalex.org/C89429830","wikidata":"https://www.wikidata.org/wiki/Q735710","display_name":"Scaffold","level":2,"score":0.2524000108242035},{"id":"https://openalex.org/C58693492","wikidata":"https://www.wikidata.org/wiki/Q551875","display_name":"Neuroimaging","level":2,"score":0.25029999017715454}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.64898/2026.10.15.757554","doi":"https://doi.org/10.64898/2026.10.15.757554","is_oa":true,"landing_page_url":"https://doi.org/10.64898/2026.10.15.757554","pdf_url":"https://www.biorxiv.org/content/biorxiv/early/2026/10/16/2026.10.15.757554.full.pdf","source":{"id":"https://openalex.org/S4306402567","display_name":"bioRxiv (Cold Spring Harbor Laboratory)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I2750212522","host_organization_name":"Cold Spring Harbor Laboratory","host_organization_lineage":["https://openalex.org/I2750212522"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"bioRxiv","raw_type":"posted-content"}],"best_oa_location":{"id":"doi:10.64898/2026.10.15.757554","doi":"https://doi.org/10.64898/2026.10.15.757554","is_oa":true,"landing_page_url":"https://doi.org/10.64898/2026.10.15.757554","pdf_url":"https://www.biorxiv.org/content/biorxiv/early/2026/10/16/2026.10.15.757554.full.pdf","source":{"id":"https://openalex.org/S4306402567","display_name":"bioRxiv (Cold Spring Harbor Laboratory)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I2750212522","host_organization_name":"Cold Spring Harbor Laboratory","host_organization_lineage":["https://openalex.org/I2750212522"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"bioRxiv","raw_type":"posted-content"},"sustainable_development_goals":[],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W7222886979.pdf","grobid_xml":"https://content.openalex.org/works/W7222886979.grobid-xml"},"referenced_works_count":25,"referenced_works":["https://openalex.org/W1557605126","https://openalex.org/W1982134291","https://openalex.org/W1999653836","https://openalex.org/W2020652754","https://openalex.org/W2058046532","https://openalex.org/W2084148650","https://openalex.org/W2118635321","https://openalex.org/W2120078534","https://openalex.org/W2122803078","https://openalex.org/W2155847838","https://openalex.org/W2167822639","https://openalex.org/W2311303842","https://openalex.org/W2623598950","https://openalex.org/W2752739326","https://openalex.org/W2963913999","https://openalex.org/W3046452378","https://openalex.org/W3182011398","https://openalex.org/W3201884881","https://openalex.org/W4306180778","https://openalex.org/W4321497950","https://openalex.org/W4360976795","https://openalex.org/W4386566010","https://openalex.org/W4416204604","https://openalex.org/W7172326483","https://openalex.org/W7203652064"],"related_works":["https://openalex.org/W7203652064","https://openalex.org/W2102707829","https://openalex.org/W3182011398","https://openalex.org/W4404743463","https://openalex.org/W1979832296","https://openalex.org/W2963913999","https://openalex.org/W1988597888","https://openalex.org/W6884789418","https://openalex.org/W2987398824","https://openalex.org/W4360825323"],"abstract_inverted_index":{"Abstract":[0],"Whole-brain":[1],"dynamics":[2],"unfold":[3],"as":[4,10],"fast,":[5],"discrete,":[6],"transient":[7,48],"events":[8],"known":[9],"neuronal":[11,165],"avalanches,":[12],"whose":[13],"propagation":[14],"is":[15,99,112,125],"constrained":[16],"by":[17],"the":[18,22,29,32,35,39,42,71,79,83,91,103,136],"connectome,":[19],"that":[20,90,111,135,154],"is,":[21],"large-scale":[23],"scaffolding":[24],"of":[25,34,41,46,74,85,93,138],"structural":[26,72,104,155],"connections":[27],"wiring":[28],"brain.":[30],"However,":[31],"role":[33],"connectome":[36],"in":[37],"determining":[38],"topographies":[40],"start":[43],"and":[44,57,82,95,120,128,163],"end":[45,84],"these":[47],"cascades":[49],"remains":[50],"unclear.":[51],"Leveraging":[52],"resting-state":[53],"Magnetoencephalography":[54],"(MEG)":[55],"recordings":[56],"diffusion":[58],"magnetic":[59],"resonance":[60],"imaging":[61],"(dMRI)":[62],"tractography":[63],"across":[64,130],"42":[65],"healthy":[66],"individuals,":[67],"we":[68],"examined":[69],"whether":[70],"architecture":[73],"white":[75],"matter":[76],"tracts":[77],"dictates":[78],"spatial":[80,117],"origins":[81],"cortical":[86],"avalanches.":[87,166],"We":[88],"found":[89],"probability":[92],"triggering":[94],"finishing":[96],"an":[97],"avalanche":[98,139],"strongly":[100],"related":[101],"to":[102,115,161],"nodal":[105],"strength,":[106],"showing":[107],"a":[108,158],"positive":[109],"correlation":[110],"highly":[113,126],"robust":[114,129],"non-parametric":[116],"permutation":[118],"testing":[119],"bootstrapping.":[121],"This":[122],"structure-function":[123],"coupling":[124],"stable":[127],"different":[131],"activation":[132],"thresholds,":[133],"demonstrating":[134],"choice":[137],"extraction":[140],"threshold":[141],"does":[142],"not":[143],"drive":[144],"or":[145],"alter":[146],"our":[147,151],"main":[148],"findings.":[149],"Collectively,":[150],"results":[152],"suggest":[153],"properties":[156],"determine":[157],"region\u2019s":[159],"propensity":[160],"initiate":[162],"terminate":[164]},"counts_by_year":[],"updated_date":"2026-11-06T12:05:46.655746","created_date":"2026-10-19T00:00:00"}