{"id":"https://openalex.org/W7222885083","doi":"https://doi.org/10.64898/2026.10.12.757951","title":"The ovarian cycle and estradiol modulate cortical network state and auditory entrainment in mice and women","display_name":"The ovarian cycle and estradiol modulate cortical network state and auditory entrainment in mice and women","publication_year":2026,"publication_date":"2026-10-18","ids":{"openalex":"https://openalex.org/W7222885083","doi":"https://doi.org/10.64898/2026.10.12.757951"},"language":"en","primary_location":{"id":"doi:10.64898/2026.10.12.757951","doi":"https://doi.org/10.64898/2026.10.12.757951","is_oa":true,"landing_page_url":"https://doi.org/10.64898/2026.10.12.757951","pdf_url":"https://www.biorxiv.org/content/biorxiv/early/2026/10/18/2026.10.12.757951.full.pdf","source":{"id":"https://openalex.org/S4306402567","display_name":"bioRxiv (Cold Spring Harbor Laboratory)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I2750212522","host_organization_name":"Cold Spring Harbor Laboratory","host_organization_lineage":["https://openalex.org/I2750212522"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"bioRxiv","raw_type":"posted-content"},"volume":null,"type":"preprint","is_traditional":true,"indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.biorxiv.org/content/biorxiv/early/2026/10/18/2026.10.12.757951.full.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5159021069","display_name":"Maria Isabel Carreno Munoz","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2802351361","display_name":"Centre Hospitalier Universitaire Sainte-Justine","ror":"https://ror.org/01gv74p78","country_code":"CA","type":"healthcare","lineage":["https://openalex.org/I2801902503","https://openalex.org/I2802351361","https://openalex.org/I4210139015","https://openalex.org/I4405279980"]},{"id":"https://openalex.org/I4405268511","display_name":"CHU Sainte-Justine Research Center","ror":"https://ror.org/016e4fa89","country_code":"CA","type":"facility","lineage":["https://openalex.org/I4405268511"]},{"id":"https://openalex.org/I70931966","display_name":"Universit\u00e9 de Montr\u00e9al","ror":"https://ror.org/0161xgx34","country_code":"CA","type":"education","lineage":["https://openalex.org/I70931966"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Maria Isabel Carre\u00f1o-Mu\u00f1oz","raw_affiliation_strings":["Centre de Recherche, CHU Sainte-Justine (CHUSJ)","Neurosciences Department, Universit\u00e9 de Montr\u00e9al"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Centre de Recherche, CHU Sainte-Justine (CHUSJ)","institution_ids":["https://openalex.org/I2802351361","https://openalex.org/I4405268511"]},{"raw_affiliation_string":"Neurosciences Department, Universit\u00e9 de Montr\u00e9al","institution_ids":["https://openalex.org/I70931966"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5049286820","display_name":"Pegah Chehrazi","orcid":"https://orcid.org/0000-0001-9956-3249","observed_orcids":["https://orcid.org/0000-0001-9956-3249"]},"institutions":[{"id":"https://openalex.org/I2802351361","display_name":"Centre Hospitalier Universitaire Sainte-Justine","ror":"https://ror.org/01gv74p78","country_code":"CA","type":"healthcare","lineage":["https://openalex.org/I2801902503","https://openalex.org/I2802351361","https://openalex.org/I4210139015","https://openalex.org/I4405279980"]},{"id":"https://openalex.org/I4405268511","display_name":"CHU Sainte-Justine Research Center","ror":"https://ror.org/016e4fa89","country_code":"CA","type":"facility","lineage":["https://openalex.org/I4405268511"]},{"id":"https://openalex.org/I70931966","display_name":"Universit\u00e9 de Montr\u00e9al","ror":"https://ror.org/0161xgx34","country_code":"CA","type":"education","lineage":["https://openalex.org/I70931966"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Pegah Chehrazi","raw_affiliation_strings":["Centre de Recherche, CHU Sainte-Justine (CHUSJ)","Neurosciences Department, Universit\u00e9 de Montr\u00e9al"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Centre de Recherche, CHU Sainte-Justine (CHUSJ)","institution_ids":["https://openalex.org/I2802351361","https://openalex.org/I4405268511"]},{"raw_affiliation_string":"Neurosciences Department, Universit\u00e9 de Montr\u00e9al","institution_ids":["https://openalex.org/I70931966"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5015595003","display_name":"Alessandra G. Ciancone Chama","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2802351361","display_name":"Centre Hospitalier Universitaire Sainte-Justine","ror":"https://ror.org/01gv74p78","country_code":"CA","type":"healthcare","lineage":["https://openalex.org/I2801902503","https://openalex.org/I2802351361","https://openalex.org/I4210139015","https://openalex.org/I4405279980"]},{"id":"https://openalex.org/I4405268511","display_name":"CHU Sainte-Justine Research Center","ror":"https://ror.org/016e4fa89","country_code":"CA","type":"facility","lineage":["https://openalex.org/I4405268511"]},{"id":"https://openalex.org/I70931966","display_name":"Universit\u00e9 de Montr\u00e9al","ror":"https://ror.org/0161xgx34","country_code":"CA","type":"education","lineage":["https://openalex.org/I70931966"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Alessandra Ciancone Chama","raw_affiliation_strings":["Centre de Recherche, CHU Sainte-Justine (CHUSJ)","Neurosciences Department, Universit\u00e9 de Montr\u00e9al"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Centre de Recherche, CHU Sainte-Justine (CHUSJ)","institution_ids":["https://openalex.org/I2802351361","https://openalex.org/I4405268511"]},{"raw_affiliation_string":"Neurosciences Department, Universit\u00e9 de Montr\u00e9al","institution_ids":["https://openalex.org/I70931966"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5159005492","display_name":"Inga Knoth","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2802351361","display_name":"Centre Hospitalier Universitaire Sainte-Justine","ror":"https://ror.org/01gv74p78","country_code":"CA","type":"healthcare","lineage":["https://openalex.org/I2801902503","https://openalex.org/I2802351361","https://openalex.org/I4210139015","https://openalex.org/I4405279980"]},{"id":"https://openalex.org/I4405268511","display_name":"CHU Sainte-Justine Research Center","ror":"https://ror.org/016e4fa89","country_code":"CA","type":"facility","lineage":["https://openalex.org/I4405268511"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Inga Knoth","raw_affiliation_strings":["Centre de Recherche, CHU Sainte-Justine (CHUSJ)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Centre de Recherche, CHU Sainte-Justine (CHUSJ)","institution_ids":["https://openalex.org/I2802351361","https://openalex.org/I4405268511"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5159006445","display_name":"Samia Antonia Fernandes do Nascimento","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2802351361","display_name":"Centre Hospitalier Universitaire Sainte-Justine","ror":"https://ror.org/01gv74p78","country_code":"CA","type":"healthcare","lineage":["https://openalex.org/I2801902503","https://openalex.org/I2802351361","https://openalex.org/I4210139015","https://openalex.org/I4405279980"]},{"id":"https://openalex.org/I4405268511","display_name":"CHU Sainte-Justine Research Center","ror":"https://ror.org/016e4fa89","country_code":"CA","type":"facility","lineage":["https://openalex.org/I4405268511"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Ant\u00f4nia Samia Fernandes do Nascimento","raw_affiliation_strings":["Centre de Recherche, CHU Sainte-Justine (CHUSJ)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Centre de Recherche, CHU Sainte-Justine (CHUSJ)","institution_ids":["https://openalex.org/I2802351361","https://openalex.org/I4405268511"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5159003563","display_name":"Benjamin Campbell","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2802351361","display_name":"Centre Hospitalier Universitaire Sainte-Justine","ror":"https://ror.org/01gv74p78","country_code":"CA","type":"healthcare","lineage":["https://openalex.org/I2801902503","https://openalex.org/I2802351361","https://openalex.org/I4210139015","https://openalex.org/I4405279980"]},{"id":"https://openalex.org/I4405268511","display_name":"CHU Sainte-Justine Research Center","ror":"https://ror.org/016e4fa89","country_code":"CA","type":"facility","lineage":["https://openalex.org/I4405268511"]},{"id":"https://openalex.org/I70931966","display_name":"Universit\u00e9 de Montr\u00e9al","ror":"https://ror.org/0161xgx34","country_code":"CA","type":"education","lineage":["https://openalex.org/I70931966"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Benjamin F.N. Campbell","raw_affiliation_strings":["Centre de Recherche, CHU Sainte-Justine (CHUSJ)","Neurosciences Department, Universit\u00e9 de Montr\u00e9al"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Centre de Recherche, CHU Sainte-Justine (CHUSJ)","institution_ids":["https://openalex.org/I2802351361","https://openalex.org/I4405268511"]},{"raw_affiliation_string":"Neurosciences Department, Universit\u00e9 de Montr\u00e9al","institution_ids":["https://openalex.org/I70931966"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5030409754","display_name":"Jozsef Csicsvari","orcid":"https://orcid.org/0000-0002-5193-4036","observed_orcids":["https://orcid.org/0000-0002-5193-4036"]},"institutions":[{"id":"https://openalex.org/I157556583","display_name":"Institute of Science and Technology Austria","ror":"https://ror.org/03gnh5541","country_code":"AT","type":"education","lineage":["https://openalex.org/I157556583"]}],"countries":["AT"],"is_corresponding":false,"raw_author_name":"Jozsef Csicsvari","raw_affiliation_strings":["Institute of Science and Technology (ISTA) Austria, 3400 Klosterneuburg, Austria"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Science and Technology (ISTA) Austria, 3400 Klosterneuburg, Austria","institution_ids":["https://openalex.org/I157556583"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5086260987","display_name":"Bidisha Chattopadhyaya","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2802351361","display_name":"Centre Hospitalier Universitaire Sainte-Justine","ror":"https://ror.org/01gv74p78","country_code":"CA","type":"healthcare","lineage":["https://openalex.org/I2801902503","https://openalex.org/I2802351361","https://openalex.org/I4210139015","https://openalex.org/I4405279980"]},{"id":"https://openalex.org/I4405268511","display_name":"CHU Sainte-Justine Research Center","ror":"https://ror.org/016e4fa89","country_code":"CA","type":"facility","lineage":["https://openalex.org/I4405268511"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Bidisha Chattopadhyaya","raw_affiliation_strings":["Centre de Recherche, CHU Sainte-Justine (CHUSJ)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Centre de Recherche, CHU Sainte-Justine (CHUSJ)","institution_ids":["https://openalex.org/I2802351361","https://openalex.org/I4405268511"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5055427963","display_name":"Sarah Lipp\u00e9","orcid":"https://orcid.org/0000-0002-4430-1644","observed_orcids":["https://orcid.org/0000-0002-4430-1644"]},"institutions":[{"id":"https://openalex.org/I2802351361","display_name":"Centre Hospitalier Universitaire Sainte-Justine","ror":"https://ror.org/01gv74p78","country_code":"CA","type":"healthcare","lineage":["https://openalex.org/I2801902503","https://openalex.org/I2802351361","https://openalex.org/I4210139015","https://openalex.org/I4405279980"]},{"id":"https://openalex.org/I4405268511","display_name":"CHU Sainte-Justine Research Center","ror":"https://ror.org/016e4fa89","country_code":"CA","type":"facility","lineage":["https://openalex.org/I4405268511"]},{"id":"https://openalex.org/I70931966","display_name":"Universit\u00e9 de Montr\u00e9al","ror":"https://ror.org/0161xgx34","country_code":"CA","type":"education","lineage":["https://openalex.org/I70931966"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Sarah Lipp\u00e9","raw_affiliation_strings":["Centre de Recherche, CHU Sainte-Justine (CHUSJ)","Department of Psychology, Universit\u00e9 de Montr\u00e9al, Montreal, QC, Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Centre de Recherche, CHU Sainte-Justine (CHUSJ)","institution_ids":["https://openalex.org/I2802351361","https://openalex.org/I4405268511"]},{"raw_affiliation_string":"Department of Psychology, Universit\u00e9 de Montr\u00e9al, Montreal, QC, Canada","institution_ids":["https://openalex.org/I70931966"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5039537483","display_name":"Graziella Di Cristo","orcid":"https://orcid.org/0000-0003-4464-4994","observed_orcids":["https://orcid.org/0000-0003-4464-4994","https://orcid.org/0000-0003-3659-9783"]},"institutions":[{"id":"https://openalex.org/I2802351361","display_name":"Centre Hospitalier Universitaire Sainte-Justine","ror":"https://ror.org/01gv74p78","country_code":"CA","type":"healthcare","lineage":["https://openalex.org/I2801902503","https://openalex.org/I2802351361","https://openalex.org/I4210139015","https://openalex.org/I4405279980"]},{"id":"https://openalex.org/I4405268511","display_name":"CHU Sainte-Justine Research Center","ror":"https://ror.org/016e4fa89","country_code":"CA","type":"facility","lineage":["https://openalex.org/I4405268511"]},{"id":"https://openalex.org/I70931966","display_name":"Universit\u00e9 de Montr\u00e9al","ror":"https://ror.org/0161xgx34","country_code":"CA","type":"education","lineage":["https://openalex.org/I70931966"]}],"countries":["CA"],"is_corresponding":true,"raw_author_name":"Graziella Di Cristo","raw_affiliation_strings":["Centre de Recherche, CHU Sainte-Justine (CHUSJ)","Neurosciences Department, Universit\u00e9 de Montr\u00e9al"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Centre de Recherche, CHU Sainte-Justine (CHUSJ)","institution_ids":["https://openalex.org/I2802351361","https://openalex.org/I4405268511"]},{"raw_affiliation_string":"Neurosciences Department, Universit\u00e9 de Montr\u00e9al","institution_ids":["https://openalex.org/I70931966"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5039537483"],"corresponding_institution_ids":["https://openalex.org/I2802351361","https://openalex.org/I4405268511","https://openalex.org/I70931966"],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10581","display_name":"Neural dynamics and brain function","score":0.9916999936103821,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10581","display_name":"Neural dynamics and brain function","score":0.9916999936103821,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10077","display_name":"Neuroscience and Neuropharmacology Research","score":0.003700000001117587,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10756","display_name":"Estrogen and related hormone effects","score":0.00139999995008111,"subfield":{"id":"https://openalex.org/subfields/1310","display_name":"Endocrinology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/ovarian-cycle","display_name":"ovarian cycle","score":0.9649999737739563},{"id":"https://openalex.org/keywords/estradiol","display_name":"estradiol","score":1.0},{"id":"https://openalex.org/keywords/auditory-entrainment","display_name":"auditory entrainment","score":0.9980000257492065},{"id":"https://openalex.org/keywords/electroencephalography","display_name":"EEG","score":0.49900001287460327},{"id":"https://openalex.org/keywords/local-field-potentials","display_name":"local field potentials","score":0.8700000047683716},{"id":"https://openalex.org/keywords/fast-spiking-interneurons","display_name":"fast-spiking interneurons","score":0.9120000004768372},{"id":"https://openalex.org/keywords/excitation-inhibition-balance","display_name":"excitation-inhibition balance","score":0.9259999990463257},{"id":"https://openalex.org/keywords/sex-hormones","display_name":"sex hormones","score":0.6169999837875366},{"id":"https://openalex.org/keywords/mice","display_name":"mice","score":0.5889999866485596},{"id":"https://openalex.org/keywords/women","display_name":"women","score":0.8669999837875366}],"concepts":[{"id":"https://openalex.org/C1998276","wikidata":"https://www.wikidata.org/wiki/Q388121","display_name":"Estrous cycle","level":2,"score":0.6524999737739563},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.5627999901771545},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.5170000195503235},{"id":"https://openalex.org/C139992725","wikidata":"https://www.wikidata.org/wiki/Q5380656","display_name":"Entrainment (biomusicology)","level":3,"score":0.5044000148773193},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.4869000017642975},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.4778999984264374},{"id":"https://openalex.org/C17077164","wikidata":"https://www.wikidata.org/wiki/Q1185869","display_name":"Inhibitory postsynaptic potential","level":2,"score":0.47510001063346863},{"id":"https://openalex.org/C187785154","wikidata":"https://www.wikidata.org/wiki/Q5464664","display_name":"Follicular phase","level":2,"score":0.4738999903202057},{"id":"https://openalex.org/C135343436","wikidata":"https://www.wikidata.org/wiki/Q170406","display_name":"Rhythm","level":2,"score":0.45089998841285706},{"id":"https://openalex.org/C117838684","wikidata":"https://www.wikidata.org/wiki/Q533483","display_name":"Local field potential","level":2,"score":0.42579999566078186},{"id":"https://openalex.org/C2780297895","wikidata":"https://www.wikidata.org/wiki/Q18676","display_name":"Auditory cortex","level":2,"score":0.4025000035762787},{"id":"https://openalex.org/C2779058012","wikidata":"https://www.wikidata.org/wiki/Q83864","display_name":"Menstrual cycle","level":3,"score":0.39559999108314514},{"id":"https://openalex.org/C552161191","wikidata":"https://www.wikidata.org/wiki/Q185080","display_name":"Midbrain","level":3,"score":0.3813000023365021},{"id":"https://openalex.org/C71315377","wikidata":"https://www.wikidata.org/wiki/Q11364","display_name":"Hormone","level":2,"score":0.36469998955726624},{"id":"https://openalex.org/C24998067","wikidata":"https://www.wikidata.org/wiki/Q4114622","display_name":"Stimulation","level":2,"score":0.3637000024318695},{"id":"https://openalex.org/C16613235","wikidata":"https://www.wikidata.org/wiki/Q285982","display_name":"Endogeny","level":2,"score":0.35100001096725464},{"id":"https://openalex.org/C2781291010","wikidata":"https://www.wikidata.org/wiki/Q178580","display_name":"Period (music)","level":2,"score":0.3411000072956085},{"id":"https://openalex.org/C47611674","wikidata":"https://www.wikidata.org/wiki/Q849491","display_name":"Neuroplasticity","level":2,"score":0.32739999890327454},{"id":"https://openalex.org/C94487597","wikidata":"https://www.wikidata.org/wiki/Q11101","display_name":"Sensory system","level":2,"score":0.3273000121116638},{"id":"https://openalex.org/C2781347215","wikidata":"https://www.wikidata.org/wiki/Q4863332","display_name":"Barrel cortex","level":3,"score":0.31380000710487366},{"id":"https://openalex.org/C74254510","wikidata":"https://www.wikidata.org/wiki/Q7240508","display_name":"Premovement neuronal activity","level":2,"score":0.3050000071525574},{"id":"https://openalex.org/C121446783","wikidata":"https://www.wikidata.org/wiki/Q208353","display_name":"Circadian rhythm","level":2,"score":0.29440000653266907},{"id":"https://openalex.org/C2778575703","wikidata":"https://www.wikidata.org/wiki/Q50265477","display_name":"Luteinizing hormone","level":3,"score":0.29319998621940613},{"id":"https://openalex.org/C2777164284","wikidata":"https://www.wikidata.org/wiki/Q277954","display_name":"Estrogen","level":2,"score":0.2890999913215637},{"id":"https://openalex.org/C2777702977","wikidata":"https://www.wikidata.org/wiki/Q187082","display_name":"Ovulation","level":3,"score":0.2549000084400177},{"id":"https://openalex.org/C2778914748","wikidata":"https://www.wikidata.org/wiki/Q10850","display_name":"Rodent","level":2,"score":0.25450000166893005},{"id":"https://openalex.org/C2777670902","wikidata":"https://www.wikidata.org/wiki/Q492038","display_name":"Human brain","level":2,"score":0.2524000108242035},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.251800000667572}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.64898/2026.10.12.757951","doi":"https://doi.org/10.64898/2026.10.12.757951","is_oa":true,"landing_page_url":"https://doi.org/10.64898/2026.10.12.757951","pdf_url":"https://www.biorxiv.org/content/biorxiv/early/2026/10/18/2026.10.12.757951.full.pdf","source":{"id":"https://openalex.org/S4306402567","display_name":"bioRxiv (Cold Spring Harbor Laboratory)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I2750212522","host_organization_name":"Cold Spring Harbor Laboratory","host_organization_lineage":["https://openalex.org/I2750212522"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"bioRxiv","raw_type":"posted-content"}],"best_oa_location":{"id":"doi:10.64898/2026.10.12.757951","doi":"https://doi.org/10.64898/2026.10.12.757951","is_oa":true,"landing_page_url":"https://doi.org/10.64898/2026.10.12.757951","pdf_url":"https://www.biorxiv.org/content/biorxiv/early/2026/10/18/2026.10.12.757951.full.pdf","source":{"id":"https://openalex.org/S4306402567","display_name":"bioRxiv (Cold Spring Harbor Laboratory)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I2750212522","host_organization_name":"Cold Spring Harbor Laboratory","host_organization_lineage":["https://openalex.org/I2750212522"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"bioRxiv","raw_type":"posted-content"},"sustainable_development_goals":[{"score":0.5683000087738037,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G927852686","display_name":null,"funder_award_id":"456461541","funder_id":"https://openalex.org/F4320334593","funder_display_name":"Natural Sciences and Engineering Research Council of Canada"}],"funders":[{"id":"https://openalex.org/F4320314000","display_name":"Compute Canada","ror":"https://ror.org/03ty8yr27"},{"id":"https://openalex.org/F4320317296","display_name":"Institut des maladies g\u00e9n\u00e9tiques Imagine","ror":"https://ror.org/05rq3rb55"},{"id":"https://openalex.org/F4320319909","display_name":"Savoy Foundation","ror":"https://ror.org/016kmmx43"},{"id":"https://openalex.org/F4320326640","display_name":"Centre hospitalier universitaire Sainte-Justine","ror":"https://ror.org/01gv74p78"},{"id":"https://openalex.org/F4320334506","display_name":"Canadian Institutes of Health Research","ror":"https://ror.org/01gavpb45"},{"id":"https://openalex.org/F4320334593","display_name":"Natural Sciences and Engineering Research Council of Canada","ror":"https://ror.org/01h531d29"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W7222885083.pdf","grobid_xml":"https://content.openalex.org/works/W7222885083.grobid-xml"},"referenced_works_count":68,"referenced_works":["https://openalex.org/W231172225","https://openalex.org/W1449283962","https://openalex.org/W1488634403","https://openalex.org/W1516762603","https://openalex.org/W1857638364","https://openalex.org/W1970513158","https://openalex.org/W1978069221","https://openalex.org/W2000775105","https://openalex.org/W2027045997","https://openalex.org/W2032679733","https://openalex.org/W2043538985","https://openalex.org/W2052195926","https://openalex.org/W2054442895","https://openalex.org/W2057987333","https://openalex.org/W2065683049","https://openalex.org/W2120768649","https://openalex.org/W2128495200","https://openalex.org/W2151442629","https://openalex.org/W2165130941","https://openalex.org/W2170814877","https://openalex.org/W2203314189","https://openalex.org/W2340329145","https://openalex.org/W2529942590","https://openalex.org/W2583043773","https://openalex.org/W2583201344","https://openalex.org/W2587947220","https://openalex.org/W2799431740","https://openalex.org/W2801534918","https://openalex.org/W2887114371","https://openalex.org/W2909755612","https://openalex.org/W2911866952","https://openalex.org/W2915916908","https://openalex.org/W2949606941","https://openalex.org/W2951503596","https://openalex.org/W2957441786","https://openalex.org/W2975966138","https://openalex.org/W2977358432","https://openalex.org/W2993557096","https://openalex.org/W3020594651","https://openalex.org/W3045808667","https://openalex.org/W3081866473","https://openalex.org/W3110151578","https://openalex.org/W3161478873","https://openalex.org/W3184272708","https://openalex.org/W3200422364","https://openalex.org/W3206856114","https://openalex.org/W3207386406","https://openalex.org/W3212968053","https://openalex.org/W4224264930","https://openalex.org/W4281689149","https://openalex.org/W4284695892","https://openalex.org/W4285795229","https://openalex.org/W4286249762","https://openalex.org/W4292092795","https://openalex.org/W4313307177","https://openalex.org/W4319334505","https://openalex.org/W4320487104","https://openalex.org/W4321494451","https://openalex.org/W4366190504","https://openalex.org/W4367297854","https://openalex.org/W4386022255","https://openalex.org/W4391605800","https://openalex.org/W4391924280","https://openalex.org/W4391930273","https://openalex.org/W4392239029","https://openalex.org/W4407803285","https://openalex.org/W4409178196","https://openalex.org/W7166743834"],"related_works":["https://openalex.org/W2799723383","https://openalex.org/W2015617072","https://openalex.org/W1988808602","https://openalex.org/W3038831287","https://openalex.org/W2010346062","https://openalex.org/W1963912375","https://openalex.org/W7095694552","https://openalex.org/W2790451454","https://openalex.org/W2485670701","https://openalex.org/W1974225136"],"abstract_inverted_index":{"ABSTRACT":[0],"The":[1],"human":[2,95],"brain":[3,63],"is":[4],"remarkably":[5],"dynamic,":[6],"continuously":[7],"adapting":[8],"to":[9,30,48,61],"internal":[10],"and":[11,16,22,34,58,68,84,94,103,105,112,140,172,190,206,234],"external":[12],"signals":[13],"across":[14,88],"rapid":[15],"protracted":[17],"timescales.":[18],"While":[19],"both":[20,204],"male":[21,111],"female":[23,41,113],"brains":[24],"are":[25],"influenced":[26],"by":[27,127],"sex":[28],"hormones":[29,51],"drive":[31,171],"adaptive":[32],"behavioural":[33],"physiological":[35],"changes,":[36],"the":[37,70,89,181,188,217,239],"ovarian":[38,71,90,124],"cycle":[39,72,91,125],"in":[40,92,101,110,134,138,147,150],"mammals":[42],"represents":[43],"a":[44,162,177],"conserved":[45,248],"naturalistic":[46],"model":[47,249],"understand":[49,66],"how":[50,69],"such":[52],"as":[53,245],"estradiol":[54,158,228],"(E2)":[55],"alter":[56],"cellular":[57],"network":[59,80,232],"states":[60,233],"shape":[62],"function.":[64],"To":[65],"whether":[67],"influences":[73],"sensory":[74],"cortical":[75,79,231],"processing,":[76],"we":[77],"investigated":[78],"activity":[81,100],"at":[82],"rest":[83],"upon":[85],"auditory":[86,174,235],"stimulation":[87],"mice":[93],"subjects.":[96],"We":[97],"recorded":[98],"EEG":[99],"men":[102],"women":[104],"intracortical":[106],"local":[107],"field":[108],"potentials":[109],"mice.":[114],"Female":[115],"participants":[116],"were":[117],"tested":[118],"during":[119,203],"two":[120],"phases":[121],"of":[122,194,220,241],"their":[123,200],"characterized":[126],"low":[128],"E2":[129,142,185,211],"levels":[130,143],"(early":[131],"follicular":[132,145],"phase":[133,146],"women;":[135,148],"late":[136],"estrus":[137],"mice)":[139],"high":[141,154,184],"(late":[144],"proestrus":[149],"mice).":[151],"Across":[152],"species,":[153],"endogenous":[155],"or":[156],"exogenous":[157],"was":[159],"associated":[160],"with":[161],"steeper":[163],"aperiodic":[164],"power":[165],"spectral":[166],"slope,":[167],"indicating":[168],"decreased":[169],"excitatory/inhibitory":[170],"attenuated":[173],"entrainment":[175],"following":[176],"40Hz":[178],"stimulation.":[179],"At":[180],"single-cell":[182],"level,":[183],"selectively":[186],"increased":[187],"baseline":[189],"sustained":[191],"40-Hz":[192],"firing":[193],"putative":[195],"fast-spiking":[196],"interneurons":[197],"while":[198,215],"reducing":[199],"temporal":[201,218],"coherence":[202],"spontaneous":[205],"stimulus-evoked":[207],"activity,":[208],"suggesting":[209],"that":[210,227],"enhances":[212],"inhibitory":[213,221],"tone,":[214],"disrupting":[216],"coordination":[219],"networks.":[222],"Altogether,":[223],"these":[224],"findings":[225],"demonstrate":[226],"dynamically":[229],"modulates":[230],"responsiveness.":[236],"This":[237],"underscores":[238],"necessity":[240],"investigating":[242],"hormone-brain":[243],"coupling":[244],"an":[246],"evolutionarily":[247],"essential":[250],"for":[251],"yielding":[252],"translational":[253],"insights":[254],"into":[255],"sex-specific":[256],"neurobiology.":[257]},"counts_by_year":[],"updated_date":"2026-11-09T13:22:03.289127","created_date":"2026-10-19T00:00:00"}