{"id":"https://openalex.org/W7222779873","doi":"https://doi.org/10.1136/bmjopen-2026-120128","title":"Cancer incidence following platelet count and C-reactive protein testing across ethnic groups in English primary care: a cohort study of 5 million patients","display_name":"Cancer incidence following platelet count and C-reactive protein testing across ethnic groups in English primary care: a cohort study of 5 million patients","publication_year":2026,"publication_date":"2026-10-01","ids":{"openalex":"https://openalex.org/W7222779873","doi":"https://doi.org/10.1136/bmjopen-2026-120128","pmid":"https://pubmed.ncbi.nlm.nih.gov/42933828","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/13711558"},"language":"en","primary_location":{"id":"doi:10.1136/bmjopen-2026-120128","doi":"https://doi.org/10.1136/bmjopen-2026-120128","is_oa":true,"landing_page_url":"https://doi.org/10.1136/bmjopen-2026-120128","pdf_url":null,"source":{"id":"https://openalex.org/S79054089","display_name":"BMJ Open","issn_l":"2044-6055","issn":["2044-6055"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319945","host_organization_name":"BMJ","host_organization_lineage":["https://openalex.org/P4310319945"],"host_organization_lineage_names":["BMJ"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMJ Open","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://doi.org/10.1136/bmjopen-2026-120128","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5074873925","display_name":"Melissa Barlow","orcid":"https://orcid.org/0000-0002-0746-1868","observed_orcids":["https://orcid.org/0000-0002-0746-1868"]},"institutions":[{"id":"https://openalex.org/I23923803","display_name":"University of Exeter","ror":"https://ror.org/03yghzc09","country_code":"GB","type":"education","lineage":["https://openalex.org/I23923803"]}],"countries":["GB"],"is_corresponding":true,"raw_author_name":"Melissa Barlow","raw_affiliation_strings":["Department of Health and Community Sciences, St Luke\u2019s Campus, University of Exeter, Exeter, UK"],"raw_orcid":"https://orcid.org/0000-0002-0746-1868","affiliations":[{"raw_affiliation_string":"Department of Health and Community Sciences, St Luke\u2019s Campus, University of Exeter, Exeter, UK","institution_ids":["https://openalex.org/I23923803"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5036488573","display_name":"Liz Down","orcid":"https://orcid.org/0000-0002-2738-2710","observed_orcids":["https://orcid.org/0000-0002-2738-2710"]},"institutions":[{"id":"https://openalex.org/I23923803","display_name":"University of Exeter","ror":"https://ror.org/03yghzc09","country_code":"GB","type":"education","lineage":["https://openalex.org/I23923803"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Liz Down","raw_affiliation_strings":["Department of Health and Community Sciences, St Luke\u2019s Campus, University of Exeter, Exeter, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Health and Community Sciences, St Luke\u2019s Campus, University of Exeter, Exeter, UK","institution_ids":["https://openalex.org/I23923803"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5010025819","display_name":"Luke T. A. Mounce","orcid":"https://orcid.org/0000-0002-6089-0661","observed_orcids":["https://orcid.org/0000-0002-6089-0661"]},"institutions":[{"id":"https://openalex.org/I23923803","display_name":"University of Exeter","ror":"https://ror.org/03yghzc09","country_code":"GB","type":"education","lineage":["https://openalex.org/I23923803"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Luke T A Mounce","raw_affiliation_strings":["Department of Health and Community Sciences, St Luke\u2019s Campus, University of Exeter, Exeter, UK"],"raw_orcid":"https://orcid.org/0000-0002-6089-0661","affiliations":[{"raw_affiliation_string":"Department of Health and Community Sciences, St Luke\u2019s Campus, University of Exeter, Exeter, UK","institution_ids":["https://openalex.org/I23923803"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5088615477","display_name":"Samuel WD Merriel","orcid":"https://orcid.org/0000-0003-2919-9087","observed_orcids":["https://orcid.org/0000-0003-2919-9087"]},"institutions":[{"id":"https://openalex.org/I28407311","display_name":"University of Manchester","ror":"https://ror.org/027m9bs27","country_code":"GB","type":"education","lineage":["https://openalex.org/I28407311"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Samuel W D Merriel","raw_affiliation_strings":["Centre for Primary Care & Health Services Research, The University of Manchester, Manchester, UK"],"raw_orcid":"https://orcid.org/0000-0003-2919-9087","affiliations":[{"raw_affiliation_string":"Centre for Primary Care & Health Services Research, The University of Manchester, Manchester, UK","institution_ids":["https://openalex.org/I28407311"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5073791556","display_name":"Jessica Watson","orcid":"https://orcid.org/0000-0002-8177-6438","observed_orcids":["https://orcid.org/0000-0002-8177-6438"]},"institutions":[{"id":"https://openalex.org/I36234482","display_name":"University of Bristol","ror":"https://ror.org/0524sp257","country_code":"GB","type":"education","lineage":["https://openalex.org/I36234482"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Jessica Watson","raw_affiliation_strings":["Centre for Academic Primary Care (CAPC), Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK"],"raw_orcid":"https://orcid.org/0000-0002-8177-6438","affiliations":[{"raw_affiliation_string":"Centre for Academic Primary Care (CAPC), Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK","institution_ids":["https://openalex.org/I36234482"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5053884569","display_name":"Tanimola Martins","orcid":"https://orcid.org/0000-0001-5226-4073","observed_orcids":["https://orcid.org/0000-0001-5226-4073"]},"institutions":[{"id":"https://openalex.org/I23923803","display_name":"University of Exeter","ror":"https://ror.org/03yghzc09","country_code":"GB","type":"education","lineage":["https://openalex.org/I23923803"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Tanimola Martins","raw_affiliation_strings":["Department of Health and Community Sciences, St Luke\u2019s Campus, University of Exeter, Exeter, UK"],"raw_orcid":"https://orcid.org/0000-0001-5226-4073","affiliations":[{"raw_affiliation_string":"Department of Health and Community Sciences, St Luke\u2019s Campus, University of Exeter, Exeter, UK","institution_ids":["https://openalex.org/I23923803"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5156718234","display_name":"Sarah Bailey","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I165932596","display_name":"National University of Singapore","ror":"https://ror.org/01tgyzw49","country_code":"SG","type":"education","lineage":["https://openalex.org/I165932596"]},{"id":"https://openalex.org/I23923803","display_name":"University of Exeter","ror":"https://ror.org/03yghzc09","country_code":"GB","type":"education","lineage":["https://openalex.org/I23923803"]}],"countries":["GB","SG"],"is_corresponding":false,"raw_author_name":"Sarah E R Bailey","raw_affiliation_strings":["Department of Family Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore","Department of Health and Community Sciences, St Luke\u2019s Campus, University of Exeter, Exeter, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Family Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore","institution_ids":["https://openalex.org/I165932596"]},{"raw_affiliation_string":"Department of Health and Community Sciences, St Luke\u2019s Campus, University of Exeter, Exeter, UK","institution_ids":["https://openalex.org/I23923803"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5074873925"],"corresponding_institution_ids":["https://openalex.org/I23923803"],"apc_list":{"value":1500,"currency":"GBP","value_usd":1839},"apc_paid":{"value":1500,"currency":"GBP","value_usd":1839},"fwci":0.0,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":{"value":0.76428507,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"16","issue":"10","first_page":"e120128","last_page":"e120128"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11355","display_name":"Inflammatory Biomarkers in Disease Prognosis","score":0.676800012588501,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11355","display_name":"Inflammatory Biomarkers in Disease Prognosis","score":0.676800012588501,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10556","display_name":"Global Cancer Incidence and Screening","score":0.2678000032901764,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10552","display_name":"Colorectal Cancer Screening and Detection","score":0.011900000274181366,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/cancer-incidence","display_name":"cancer incidence","score":0.9869999885559082},{"id":"https://openalex.org/keywords/platelet-count","display_name":"platelet count","score":0.9629999995231628},{"id":"https://openalex.org/keywords/c-reactive-protein","display_name":"C-reactive protein","score":0.9990000128746033},{"id":"https://openalex.org/keywords/ethnic-groups","display_name":"ethnic groups","score":0.5669999718666077},{"id":"https://openalex.org/keywords/primary-care","display_name":"primary care","score":0.7570000290870667},{"id":"https://openalex.org/keywords/inflammatory-markers","display_name":"inflammatory markers","score":0.5559999942779541},{"id":"https://openalex.org/keywords/tumor-screening","display_name":"cancer screening","score":0.6190000176429749},{"id":"https://openalex.org/keywords/english-population","display_name":"English population","score":0.3009999990463257}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8478999733924866},{"id":"https://openalex.org/C61511704","wikidata":"https://www.wikidata.org/wiki/Q1671857","display_name":"Incidence (geometry)","level":2,"score":0.6067000031471252},{"id":"https://openalex.org/C201903717","wikidata":"https://www.wikidata.org/wiki/Q1778788","display_name":"Cohort study","level":2,"score":0.5467000007629395},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.5331000089645386},{"id":"https://openalex.org/C137403100","wikidata":"https://www.wikidata.org/wiki/Q41710","display_name":"Ethnic group","level":2,"score":0.5011000037193298},{"id":"https://openalex.org/C2992704333","wikidata":"https://www.wikidata.org/wiki/Q5382717","display_name":"Cancer incidence","level":3,"score":0.4408000111579895},{"id":"https://openalex.org/C72563966","wikidata":"https://www.wikidata.org/wiki/Q1303415","display_name":"Cohort","level":2,"score":0.43549999594688416},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.40869998931884766},{"id":"https://openalex.org/C89560881","wikidata":"https://www.wikidata.org/wiki/Q101026","display_name":"Platelet","level":2,"score":0.40529999136924744},{"id":"https://openalex.org/C143998085","wikidata":"https://www.wikidata.org/wiki/Q162555","display_name":"Oncology","level":1,"score":0.3686000108718872},{"id":"https://openalex.org/C107130276","wikidata":"https://www.wikidata.org/wiki/Q133805","display_name":"Epidemiology","level":2,"score":0.2946000099182129},{"id":"https://openalex.org/C167135981","wikidata":"https://www.wikidata.org/wiki/Q2146302","display_name":"Retrospective cohort study","level":2,"score":0.28130000829696655},{"id":"https://openalex.org/C188816634","wikidata":"https://www.wikidata.org/wiki/Q2113324","display_name":"Prospective cohort study","level":2,"score":0.27250000834465027},{"id":"https://openalex.org/C2779473830","wikidata":"https://www.wikidata.org/wiki/Q1540899","display_name":"MEDLINE","level":2,"score":0.2646999955177307}],"mesh":[],"locations_count":6,"locations":[{"id":"doi:10.1136/bmjopen-2026-120128","doi":"https://doi.org/10.1136/bmjopen-2026-120128","is_oa":true,"landing_page_url":"https://doi.org/10.1136/bmjopen-2026-120128","pdf_url":null,"source":{"id":"https://openalex.org/S79054089","display_name":"BMJ Open","issn_l":"2044-6055","issn":["2044-6055"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319945","host_organization_name":"BMJ","host_organization_lineage":["https://openalex.org/P4310319945"],"host_organization_lineage_names":["BMJ"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMJ Open","raw_type":"journal-article"},{"id":"doi:10.64898/2026.03.03.26347503","doi":"https://doi.org/10.64898/2026.03.03.26347503","is_oa":true,"landing_page_url":"https://doi.org/10.64898/2026.03.03.26347503","pdf_url":"https://www.medrxiv.org/content/medrxiv/early/2026/03/04/2026.03.03.26347503.full.pdf","source":{"id":"https://openalex.org/S3005729997","display_name":"medRxiv","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":["https://openalex.org/P4310315909"],"host_organization_lineage_names":["Cold Spring Harbor Laboratory Press"],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"medRxiv","raw_type":"posted-content"},{"id":"pmh:oai:pubmedcentral.nih.gov:13711558","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC13711558/","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC13711558/pdf/bmjopen-16-10.pdf","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMJ Open","raw_type":"Text"},{"id":"pmid:42933828","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/42933828","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMJ open","raw_type":"Journal Article"},{"id":"pmh:oai:doaj.org/article:45d154ca9ff14ce69d36f4e807872d43","doi":null,"is_oa":false,"landing_page_url":"https://doaj.org/article/45d154ca9ff14ce69d36f4e807872d43","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"BMJ Open, Vol 16, Iss 10 (2026)","raw_type":"article"},{"id":"pmh:oai:research-information.bris.ac.uk:openaire_cris_publications/a6369720-201d-4329-8adf-9d7f8f3fe743","doi":null,"is_oa":false,"landing_page_url":"https://research-information.bris.ac.uk/en/publications/a6369720-201d-4329-8adf-9d7f8f3fe743","pdf_url":null,"source":{"id":"https://openalex.org/S7407055359","display_name":"Explore Bristol Research","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Barlow, M, Down, L, Mounce, L, Merriel, S W D, Watson, J C, Martins, T & Bailey, S 2026, 'Cancer incidence following platelet count and C-reactive protein testing across ethnic groups in English primary care : a cohort study of 5 million patients', BMJ Open.","raw_type":"info:eu-repo/semantics/article"}],"best_oa_location":{"id":"doi:10.1136/bmjopen-2026-120128","doi":"https://doi.org/10.1136/bmjopen-2026-120128","is_oa":true,"landing_page_url":"https://doi.org/10.1136/bmjopen-2026-120128","pdf_url":null,"source":{"id":"https://openalex.org/S79054089","display_name":"BMJ Open","issn_l":"2044-6055","issn":["2044-6055"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319945","host_organization_name":"BMJ","host_organization_lineage":["https://openalex.org/P4310319945"],"host_organization_lineage_names":["BMJ"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMJ Open","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":1.0,"display_name":"Good health and well-being"},{"id":"https://metadata.un.org/sdg/10","score":0.4000000059604645,"display_name":"Reduced inequalities"}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[{"id":"https://openalex.org/G1769173504","display_name":null,"funder_award_id":"EDDCPJT/100031","funder_id":"https://openalex.org/F4320319985","funder_display_name":"Cancer Research UK"},{"id":"https://openalex.org/G2481553752","display_name":null,"funder_award_id":"C8640/A23385","funder_id":"https://openalex.org/F4320319990","funder_display_name":"National Institute for Health and Care Research"},{"id":"https://openalex.org/G3832996911","display_name":null,"funder_award_id":"(C8640/A23385)","funder_id":"https://openalex.org/F4320319985","funder_display_name":"Cancer Research UK"},{"id":"https://openalex.org/G3986422802","display_name":null,"funder_award_id":"NIHR301666","funder_id":"https://openalex.org/F4320319985","funder_display_name":"Cancer Research UK"},{"id":"https://openalex.org/G6000438162","display_name":null,"funder_award_id":"C56361/A26124","funder_id":"https://openalex.org/F4320319985","funder_display_name":"Cancer Research UK"},{"id":"https://openalex.org/G6052954810","display_name":null,"funder_award_id":"A23385","funder_id":"https://openalex.org/F4320319985","funder_display_name":"Cancer Research UK"},{"id":"https://openalex.org/G6201277709","display_name":"Supporting clinical decision making in patients with symptoms of cancer and pre-existing health conditions.","funder_award_id":"NIHR301666","funder_id":"https://openalex.org/F4320319990","funder_display_name":"National Institute for Health and Care Research"},{"id":"https://openalex.org/G7791781452","display_name":null,"funder_award_id":"C8640","funder_id":"https://openalex.org/F4320319985","funder_display_name":"Cancer Research UK"}],"funders":[{"id":"https://openalex.org/F4320319985","display_name":"Cancer Research UK","ror":"https://ror.org/054225q67"},{"id":"https://openalex.org/F4320319990","display_name":"National Institute for Health and Care Research","ror":"https://ror.org/0187kwz08"},{"id":"https://openalex.org/F4320319994","display_name":"Department of Health and Social Care","ror":"https://ror.org/03sbpja79"},{"id":"https://openalex.org/F4320334771","display_name":"Science and Engineering Research Board","ror":"https://ror.org/03ffdsr55"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W7222779873.pdf","grobid_xml":"https://content.openalex.org/works/W7222779873.grobid-xml"},"referenced_works_count":33,"referenced_works":["https://openalex.org/W1967011667","https://openalex.org/W2037852093","https://openalex.org/W2056664141","https://openalex.org/W2061355384","https://openalex.org/W2078440642","https://openalex.org/W2163278718","https://openalex.org/W2275737843","https://openalex.org/W2342469004","https://openalex.org/W2418494338","https://openalex.org/W2619583278","https://openalex.org/W2940642980","https://openalex.org/W2972519206","https://openalex.org/W2995525013","https://openalex.org/W3045744783","https://openalex.org/W3124056846","https://openalex.org/W3138329177","https://openalex.org/W3149026346","https://openalex.org/W3158323486","https://openalex.org/W3164798201","https://openalex.org/W3193259848","https://openalex.org/W4206038228","https://openalex.org/W4214903413","https://openalex.org/W4283383960","https://openalex.org/W4310593800","https://openalex.org/W4318263486","https://openalex.org/W4324139796","https://openalex.org/W4376106384","https://openalex.org/W4389155624","https://openalex.org/W4389636115","https://openalex.org/W4392401590","https://openalex.org/W4392863907","https://openalex.org/W4396675681","https://openalex.org/W4401872373"],"related_works":["https://openalex.org/W4402237846","https://openalex.org/W2905525484","https://openalex.org/W3045744783","https://openalex.org/W7112186082","https://openalex.org/W4396748994","https://openalex.org/W2425529429","https://openalex.org/W6968139927","https://openalex.org/W2970530115","https://openalex.org/W7135919651","https://openalex.org/W2408507928"],"abstract_inverted_index":{"Abstract":[0],"Background":[1],"Platelet":[2],"count":[3,89],"and":[4,48,63,98,103,124,144,156,170,190,203,220,230,249,253,309],"C-reactive":[5],"protein":[6],"(CRP)":[7],"are":[8],"blood":[9,246],"tests":[10,29,344],"commonly":[11],"used":[12,59],"in":[13,68],"primary":[14,62,331],"care":[15,66,332],"as":[16,119],"part":[17],"of":[18,27,82,113,135,146],"diagnostic":[19,255,276,343],"work":[20],"up":[21],"for":[22,138,187,193,217,223,233,266,291,296,302,310,316,322,337],"symptomatic":[23],"patients.":[24,174],"Abnormal":[25],"results":[26,273],"these":[28],"can":[30],"indicate":[31],"an":[32,44],"undetected":[33],"cancer;":[34],"however,":[35],"it":[36],"is":[37],"not":[38],"known":[39],"whether":[40],"the":[41,111,335],"association":[42],"between":[43,93,244],"abnormal":[45,272],"test":[46,247],"result":[47],"cancer":[49,74,131,163,180,212,251],"risk":[50],"varies":[51],"by":[52],"patient":[53],"ethnicity.":[54],"Methods":[55],"This":[56,329],"cohort":[57],"study":[58,333],"routinely":[60],"collected":[61],"secondary":[64],"health":[65],"records":[67],"England":[69],"with":[70,152,158,271,281],"linkage":[71],"to":[72,200,227,285,345],"national":[73],"registry":[75],"data.":[76],"Included":[77],"patients":[78,151,169,189,219,270,298,304,318,324],"had":[79],"a":[80,87,153,159,176,208,234,286],"record":[81,92,155],"ethnicity,":[83,245],"no":[84],"prior":[85],"malignancy,":[86],"platelet":[88,154,178],"or":[90,108],"CRP":[91,160,210,236,312],"1":[94],"st":[95,100],"January":[96],"2010":[97],"31":[99],"December":[101],"2017,":[102],"were":[104,242,259],"aged":[105],"40":[106],"years":[107],"over":[109],"at":[110],"time":[112],"that":[114],"test.":[115,147],"Ethnicity":[116],"was":[117,165,182,214,293,313],"categorised":[118],"White,":[120],"Asian,":[121],"Black,":[122],"Other,":[123],"Mixed.":[125],"Multi-level":[126],"logistic":[127],"regression":[128],"models":[129],"estimated":[130],"incidence":[132,164,181,198,213],"within":[133],"one-year":[134,162],"testing,":[136],"adjusted":[137],"age,":[139],"sex,":[140],"comorbidities,":[141],"BMI,":[142],"deprivation,":[143],"year":[145],"Results":[148],"Among":[149],"4,948,342":[150],"811,559":[157],"record,":[161],"highest":[166],"among":[167,172],"White":[168,188,218,282,303,323],"lowest":[171],"Asian":[173,194,224],"Following":[175],"normal":[177,209,287],"count,":[179],"1.3%":[183],"(95%":[184],"CI":[185],"1.3-1.3%)":[186],"0.63%":[191],"(0.60-0.66%)":[192],"patients;":[195],"following":[196],"thrombocytosis,":[197],"increased":[199],"4.1%":[201],"(4.0-4.2%)":[202],"1.8%":[204],"(1.5-2.0%),":[205],"respectively.":[206,238],"After":[207],"result,":[211,237,248],"1.5%":[215],"(1.4-1.5%)":[216],"0.79%":[221],"(0.71-0.88%)":[222],"patients,":[225,283],"rising":[226],"3.6%":[228],"(3.5-3.7%)":[229],"1.9%":[231],"(1.7-2.2%)":[232],"high":[235],"No":[239],"significant":[240],"interactions":[241],"found":[243],"overall":[250],"diagnosis,":[252],"similar":[254],"odds":[256,277],"ratios":[257,278],"(dOR)":[258,279],"observed":[260],"across":[261],"all":[262],"ethnic":[263],"groups.":[264],"However,":[265],"colorectal":[267],"cancer,":[268],"Black":[269,297,317],"showed":[274],"higher":[275],"compared":[280],"relative":[284],"result.":[288],"The":[289],"dOR":[290],"thrombocytosis":[292],"11.1":[294],"(7.8-15.6)":[295],"versus":[299,319],"5.7":[300],"(5.4-6.0)":[301],"(interaction":[305,325],"p":[306,326],"-value":[307],"<0.001),":[308],"raised":[311],"4.1":[314],"(2.6-6.6)":[315],"2.5":[320],"(2.3-2.7)":[321],"-value=0.043).":[327],"Conclusion":[328],"large":[330],"underscores":[334],"need":[336],"ethnically":[338],"diverse":[339],"cohorts":[340],"when":[341],"evaluating":[342],"avoid":[346],"widening":[347],"healthcare":[348],"inequalities.":[349]},"counts_by_year":[],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2026-10-17T00:00:00"}