{"id":"https://openalex.org/W7222735858","doi":"https://doi.org/10.64898/2026.10.14.759116","title":"Thalamocortical, not Intracortical, Inputs Set the Wakeful Activity Levels of Cortical Visual Inhibition","display_name":"Thalamocortical, not Intracortical, Inputs Set the Wakeful Activity Levels of Cortical Visual Inhibition","publication_year":2026,"publication_date":"2026-10-16","ids":{"openalex":"https://openalex.org/W7222735858","doi":"https://doi.org/10.64898/2026.10.14.759116"},"language":"en","primary_location":{"id":"doi:10.64898/2026.10.14.759116","doi":"https://doi.org/10.64898/2026.10.14.759116","is_oa":true,"landing_page_url":"https://doi.org/10.64898/2026.10.14.759116","pdf_url":"https://www.biorxiv.org/content/biorxiv/early/2026/10/16/2026.10.14.759116.full.pdf","source":{"id":"https://openalex.org/S4306402567","display_name":"bioRxiv (Cold Spring Harbor Laboratory)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I2750212522","host_organization_name":"Cold Spring Harbor Laboratory","host_organization_lineage":["https://openalex.org/I2750212522"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"bioRxiv","raw_type":"posted-content"},"volume":null,"type":"preprint","indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.biorxiv.org/content/biorxiv/early/2026/10/16/2026.10.14.759116.full.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5035683945","display_name":"J\u00e9r\u00e9mie Sibille","orcid":"https://orcid.org/0000-0001-6895-7405","observed_orcids":["https://orcid.org/0000-0001-6895-7405"]},"institutions":[{"id":"https://openalex.org/I2801533059","display_name":"German Center for Neurodegenerative Diseases","ror":"https://ror.org/043j0f473","country_code":"DE","type":"facility","lineage":["https://openalex.org/I1305996414","https://openalex.org/I2801533059","https://openalex.org/I4405256427"]},{"id":"https://openalex.org/I39343248","display_name":"Humboldt-Universit\u00e4t zu Berlin","ror":"https://ror.org/01hcx6992","country_code":"DE","type":"education","lineage":["https://openalex.org/I39343248"]},{"id":"https://openalex.org/I4210152641","display_name":"Bernstein Center for Computational Neuroscience Berlin","ror":"https://ror.org/05ewdps05","country_code":"DE","type":"government","lineage":["https://openalex.org/I39343248","https://openalex.org/I4210092532","https://openalex.org/I4210152641","https://openalex.org/I4577782","https://openalex.org/I7877124"]},{"id":"https://openalex.org/I75951250","display_name":"Freie Universit\u00e4t Berlin","ror":"https://ror.org/046ak2485","country_code":"DE","type":"education","lineage":["https://openalex.org/I75951250"]},{"id":"https://openalex.org/I7877124","display_name":"Charit\u00e9 \u2013 Universit\u00e4tsmedizin Berlin","ror":"https://ror.org/001w7jn25","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I7877124"]}],"countries":["DE"],"is_corresponding":true,"raw_author_name":"J\u00e9r\u00e9mie Sibille","raw_affiliation_strings":["Charit\u00e9-Universit\u00e4tsmedizin Berlin, Corporate Member of Freie Universit\u00e4t Berlin and Humboldt-Universit\u00e4t Berlin, Bernstein Center for Computational Neuroscience, 10115 Berlin, Germany","Charit\u00e9-Universit\u00e4tsmedizin Berlin, Corporate Member of Freie Universit\u00e4t Berlin and Humboldt-Universit\u00e4t Berlin, Einstein Center for Neurosciences, 10117 Berlin, Germany","Charit\u00e9-Universit\u00e4tsmedizin Berlin, Corporate Member of Freie Universit\u00e4t Berlin and Humboldt-Universit\u00e4t Berlin, Neuroscience Research Center, 10117 Berlin, Germany","German Center for Neurodegenerative Diseases (DZNE) Berlin, 10117 Berlin, Germany"],"raw_orcid":"https://orcid.org/0000-0001-6895-7405","affiliations":[{"raw_affiliation_string":"Charit\u00e9-Universit\u00e4tsmedizin Berlin, Corporate Member of Freie Universit\u00e4t Berlin and Humboldt-Universit\u00e4t Berlin, Bernstein Center for Computational Neuroscience, 10115 Berlin, Germany","institution_ids":["https://openalex.org/I4210152641","https://openalex.org/I75951250","https://openalex.org/I7877124"]},{"raw_affiliation_string":"Charit\u00e9-Universit\u00e4tsmedizin Berlin, Corporate Member of Freie Universit\u00e4t Berlin and Humboldt-Universit\u00e4t Berlin, Einstein Center for Neurosciences, 10117 Berlin, Germany","institution_ids":["https://openalex.org/I39343248","https://openalex.org/I75951250","https://openalex.org/I7877124"]},{"raw_affiliation_string":"Charit\u00e9-Universit\u00e4tsmedizin Berlin, Corporate Member of Freie Universit\u00e4t Berlin and Humboldt-Universit\u00e4t Berlin, Neuroscience Research Center, 10117 Berlin, Germany","institution_ids":["https://openalex.org/I39343248","https://openalex.org/I75951250","https://openalex.org/I7877124"]},{"raw_affiliation_string":"German Center for Neurodegenerative Diseases (DZNE) Berlin, 10117 Berlin, Germany","institution_ids":["https://openalex.org/I2801533059"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5037835170","display_name":"Kai Lun Teh","orcid":"https://orcid.org/0000-0002-5839-7026","observed_orcids":["https://orcid.org/0000-0002-5839-7026"]},"institutions":[{"id":"https://openalex.org/I4210152641","display_name":"Bernstein Center for Computational Neuroscience Berlin","ror":"https://ror.org/05ewdps05","country_code":"DE","type":"government","lineage":["https://openalex.org/I39343248","https://openalex.org/I4210092532","https://openalex.org/I4210152641","https://openalex.org/I4577782","https://openalex.org/I7877124"]},{"id":"https://openalex.org/I75951250","display_name":"Freie Universit\u00e4t Berlin","ror":"https://ror.org/046ak2485","country_code":"DE","type":"education","lineage":["https://openalex.org/I75951250"]},{"id":"https://openalex.org/I7877124","display_name":"Charit\u00e9 \u2013 Universit\u00e4tsmedizin Berlin","ror":"https://ror.org/001w7jn25","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I7877124"]},{"id":"https://openalex.org/I95793202","display_name":"Otto-von-Guericke-Universit\u00e4t Magdeburg","ror":"https://ror.org/00ggpsq73","country_code":"DE","type":"education","lineage":["https://openalex.org/I95793202"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Kai Lun Teh","raw_affiliation_strings":["Charit\u00e9-Universit\u00e4tsmedizin Berlin, Corporate Member of Freie Universit\u00e4t Berlin and Humboldt-Universit\u00e4t Berlin, Bernstein Center for Computational Neuroscience, 10115 Berlin, Germany","Institute of Biology, Otto von Guericke University Magdeburg, 39120 Magdeburg, Germany"],"raw_orcid":"https://orcid.org/0000-0002-5839-7026","affiliations":[{"raw_affiliation_string":"Charit\u00e9-Universit\u00e4tsmedizin Berlin, Corporate Member of Freie Universit\u00e4t Berlin and Humboldt-Universit\u00e4t Berlin, Bernstein Center for Computational Neuroscience, 10115 Berlin, Germany","institution_ids":["https://openalex.org/I4210152641","https://openalex.org/I75951250","https://openalex.org/I7877124"]},{"raw_affiliation_string":"Institute of Biology, Otto von Guericke University Magdeburg, 39120 Magdeburg, Germany","institution_ids":["https://openalex.org/I95793202"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5158930802","display_name":"Jasper Alus Pysall","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2801533059","display_name":"German Center for Neurodegenerative Diseases","ror":"https://ror.org/043j0f473","country_code":"DE","type":"facility","lineage":["https://openalex.org/I1305996414","https://openalex.org/I2801533059","https://openalex.org/I4405256427"]},{"id":"https://openalex.org/I39343248","display_name":"Humboldt-Universit\u00e4t zu Berlin","ror":"https://ror.org/01hcx6992","country_code":"DE","type":"education","lineage":["https://openalex.org/I39343248"]},{"id":"https://openalex.org/I75951250","display_name":"Freie Universit\u00e4t Berlin","ror":"https://ror.org/046ak2485","country_code":"DE","type":"education","lineage":["https://openalex.org/I75951250"]},{"id":"https://openalex.org/I7877124","display_name":"Charit\u00e9 \u2013 Universit\u00e4tsmedizin Berlin","ror":"https://ror.org/001w7jn25","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I7877124"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Jasper Alus Pysall","raw_affiliation_strings":["Charit\u00e9-Universit\u00e4tsmedizin Berlin, Corporate Member of Freie Universit\u00e4t Berlin and Humboldt-Universit\u00e4t Berlin, Neuroscience Research Center, 10117 Berlin, Germany","German Center for Neurodegenerative Diseases (DZNE) Berlin, 10117 Berlin, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Charit\u00e9-Universit\u00e4tsmedizin Berlin, Corporate Member of Freie Universit\u00e4t Berlin and Humboldt-Universit\u00e4t Berlin, Neuroscience Research Center, 10117 Berlin, Germany","institution_ids":["https://openalex.org/I39343248","https://openalex.org/I75951250","https://openalex.org/I7877124"]},{"raw_affiliation_string":"German Center for Neurodegenerative Diseases (DZNE) Berlin, 10117 Berlin, Germany","institution_ids":["https://openalex.org/I2801533059"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5033503615","display_name":"Jens Kremkow","orcid":"https://orcid.org/0000-0001-7077-4528","observed_orcids":["https://orcid.org/0000-0001-7077-4528"]},"institutions":[{"id":"https://openalex.org/I4210152641","display_name":"Bernstein Center for Computational Neuroscience Berlin","ror":"https://ror.org/05ewdps05","country_code":"DE","type":"government","lineage":["https://openalex.org/I39343248","https://openalex.org/I4210092532","https://openalex.org/I4210152641","https://openalex.org/I4577782","https://openalex.org/I7877124"]},{"id":"https://openalex.org/I75951250","display_name":"Freie Universit\u00e4t Berlin","ror":"https://ror.org/046ak2485","country_code":"DE","type":"education","lineage":["https://openalex.org/I75951250"]},{"id":"https://openalex.org/I7877124","display_name":"Charit\u00e9 \u2013 Universit\u00e4tsmedizin Berlin","ror":"https://ror.org/001w7jn25","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I7877124"]},{"id":"https://openalex.org/I95793202","display_name":"Otto-von-Guericke-Universit\u00e4t Magdeburg","ror":"https://ror.org/00ggpsq73","country_code":"DE","type":"education","lineage":["https://openalex.org/I95793202"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Jens Kremkow","raw_affiliation_strings":["Charit\u00e9-Universit\u00e4tsmedizin Berlin, Corporate Member of Freie Universit\u00e4t Berlin and Humboldt-Universit\u00e4t Berlin, Bernstein Center for Computational Neuroscience, 10115 Berlin, Germany","Institute of Biology, Otto von Guericke University Magdeburg, 39120 Magdeburg, Germany"],"raw_orcid":"https://orcid.org/0000-0001-7077-4528","affiliations":[{"raw_affiliation_string":"Charit\u00e9-Universit\u00e4tsmedizin Berlin, Corporate Member of Freie Universit\u00e4t Berlin and Humboldt-Universit\u00e4t Berlin, Bernstein Center for Computational Neuroscience, 10115 Berlin, Germany","institution_ids":["https://openalex.org/I4210152641","https://openalex.org/I75951250","https://openalex.org/I7877124"]},{"raw_affiliation_string":"Institute of Biology, Otto von Guericke University Magdeburg, 39120 Magdeburg, Germany","institution_ids":["https://openalex.org/I95793202"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":6,"corresponding_author_ids":["https://openalex.org/A5035683945"],"corresponding_institution_ids":["https://openalex.org/I2801533059","https://openalex.org/I39343248","https://openalex.org/I4210152641","https://openalex.org/I75951250","https://openalex.org/I7877124"],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10581","display_name":"Neural dynamics and brain function","score":0.9648000001907349,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10581","display_name":"Neural dynamics and brain function","score":0.9648000001907349,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10077","display_name":"Neuroscience and Neuropharmacology Research","score":0.025100000202655792,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10427","display_name":"Visual perception and processing mechanisms","score":0.002099999925121665,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/thalamocortical-input","display_name":"thalamocortical input","score":0.9210000038146973},{"id":"https://openalex.org/keywords/intracortical-connectivity","display_name":"intracortical connectivity","score":0.9300000071525574},{"id":"https://openalex.org/keywords/cortical-inhibition","display_name":"cortical inhibition","score":0.7450000047683716},{"id":"https://openalex.org/keywords/wakefulness","display_name":"wakefulness","score":0.7929999828338623},{"id":"https://openalex.org/keywords/visual-cortex","display_name":"visual cortex","score":0.7450000047683716},{"id":"https://openalex.org/keywords/cortical-inhibitory-neurons","display_name":"cortical inhibitory neurons","score":0.7279999852180481},{"id":"https://openalex.org/keywords/excitatory-neurons","display_name":"excitatory neurons","score":0.7950000166893005},{"id":"https://openalex.org/keywords/light-anesthesia","display_name":"light anesthesia","score":0.4830000102519989}],"concepts":[{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.8474000096321106},{"id":"https://openalex.org/C112592302","wikidata":"https://www.wikidata.org/wiki/Q1207387","display_name":"Excitatory postsynaptic potential","level":3,"score":0.7908999919891357},{"id":"https://openalex.org/C17077164","wikidata":"https://www.wikidata.org/wiki/Q1185869","display_name":"Inhibitory postsynaptic potential","level":2,"score":0.7559999823570251},{"id":"https://openalex.org/C2779320081","wikidata":"https://www.wikidata.org/wiki/Q246710","display_name":"Wakefulness","level":3,"score":0.7103999853134155},{"id":"https://openalex.org/C200170125","wikidata":"https://www.wikidata.org/wiki/Q969316","display_name":"Neurotransmission","level":3,"score":0.5066999793052673},{"id":"https://openalex.org/C50738837","wikidata":"https://www.wikidata.org/wiki/Q781492","display_name":"Optogenetics","level":2,"score":0.4309999942779541},{"id":"https://openalex.org/C2779345533","wikidata":"https://www.wikidata.org/wiki/Q75785","display_name":"Visual cortex","level":2,"score":0.4253000020980835},{"id":"https://openalex.org/C2777348757","wikidata":"https://www.wikidata.org/wiki/Q2346577","display_name":"Cortex (anatomy)","level":2,"score":0.424699991941452},{"id":"https://openalex.org/C2777222312","wikidata":"https://www.wikidata.org/wiki/Q726562","display_name":"Neocortex","level":2,"score":0.423799991607666},{"id":"https://openalex.org/C2781041448","wikidata":"https://www.wikidata.org/wiki/Q75839","display_name":"Cerebral cortex","level":2,"score":0.4007999897003174},{"id":"https://openalex.org/C2983650178","wikidata":"https://www.wikidata.org/wiki/Q75839","display_name":"Cortical neurons","level":2,"score":0.37880000472068787},{"id":"https://openalex.org/C127445978","wikidata":"https://www.wikidata.org/wiki/Q187181","display_name":"Synapse","level":2,"score":0.358599990606308},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.3483999967575073},{"id":"https://openalex.org/C2779246727","wikidata":"https://www.wikidata.org/wiki/Q184215","display_name":"Thalamus","level":2,"score":0.31690001487731934},{"id":"https://openalex.org/C74254510","wikidata":"https://www.wikidata.org/wiki/Q7240508","display_name":"Premovement neuronal activity","level":2,"score":0.30570000410079956},{"id":"https://openalex.org/C66882249","wikidata":"https://www.wikidata.org/wiki/Q169336","display_name":"Homogeneous","level":2,"score":0.29429998993873596},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.28769999742507935},{"id":"https://openalex.org/C2778794669","wikidata":"https://www.wikidata.org/wiki/Q43054","display_name":"Neuron","level":2,"score":0.2847999930381775},{"id":"https://openalex.org/C2781347215","wikidata":"https://www.wikidata.org/wiki/Q4863332","display_name":"Barrel cortex","level":3,"score":0.2752000093460083},{"id":"https://openalex.org/C185263204","wikidata":"https://www.wikidata.org/wiki/Q1154774","display_name":"Electrophysiology","level":2,"score":0.25589999556541443},{"id":"https://openalex.org/C2780196419","wikidata":"https://www.wikidata.org/wiki/Q1762173","display_name":"Nerve net","level":2,"score":0.2547000050544739},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.2533999979496002},{"id":"https://openalex.org/C172497186","wikidata":"https://www.wikidata.org/wiki/Q328835","display_name":"Somatosensory system","level":2,"score":0.2513999938964844}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.64898/2026.10.14.759116","doi":"https://doi.org/10.64898/2026.10.14.759116","is_oa":true,"landing_page_url":"https://doi.org/10.64898/2026.10.14.759116","pdf_url":"https://www.biorxiv.org/content/biorxiv/early/2026/10/16/2026.10.14.759116.full.pdf","source":{"id":"https://openalex.org/S4306402567","display_name":"bioRxiv (Cold Spring Harbor Laboratory)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I2750212522","host_organization_name":"Cold Spring Harbor Laboratory","host_organization_lineage":["https://openalex.org/I2750212522"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"bioRxiv","raw_type":"posted-content"}],"best_oa_location":{"id":"doi:10.64898/2026.10.14.759116","doi":"https://doi.org/10.64898/2026.10.14.759116","is_oa":true,"landing_page_url":"https://doi.org/10.64898/2026.10.14.759116","pdf_url":"https://www.biorxiv.org/content/biorxiv/early/2026/10/16/2026.10.14.759116.full.pdf","source":{"id":"https://openalex.org/S4306402567","display_name":"bioRxiv (Cold Spring Harbor Laboratory)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I2750212522","host_organization_name":"Cold Spring Harbor Laboratory","host_organization_lineage":["https://openalex.org/I2750212522"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"bioRxiv","raw_type":"posted-content"},"sustainable_development_goals":[],"study_designs":[],"awards":[{"id":"https://openalex.org/G3628789648","display_name":null,"funder_award_id":"KR 4062/4-1","funder_id":"https://openalex.org/F4320320879","funder_display_name":"Deutsche Forschungsgemeinschaft"},{"id":"https://openalex.org/G4528975930","display_name":null,"funder_award_id":"KR 4062/4-2","funder_id":"https://openalex.org/F4320320879","funder_display_name":"Deutsche Forschungsgemeinschaft"}],"funders":[{"id":"https://openalex.org/F4320320879","display_name":"Deutsche Forschungsgemeinschaft","ror":"https://ror.org/018mejw64"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W7222735858.pdf","grobid_xml":"https://content.openalex.org/works/W7222735858.grobid-xml"},"referenced_works_count":85,"referenced_works":["https://openalex.org/W1233556525","https://openalex.org/W1869936268","https://openalex.org/W1875306972","https://openalex.org/W1949141612","https://openalex.org/W1972869628","https://openalex.org/W1973654985","https://openalex.org/W1974067040","https://openalex.org/W1975117887","https://openalex.org/W1982782013","https://openalex.org/W1984202832","https://openalex.org/W1987521590","https://openalex.org/W1990752984","https://openalex.org/W1999282908","https://openalex.org/W2001908985","https://openalex.org/W2018085295","https://openalex.org/W2022438346","https://openalex.org/W2035067043","https://openalex.org/W2041918412","https://openalex.org/W2045933100","https://openalex.org/W2069849731","https://openalex.org/W2089242029","https://openalex.org/W2103934527","https://openalex.org/W2129317350","https://openalex.org/W2138635047","https://openalex.org/W2145117823","https://openalex.org/W2152527426","https://openalex.org/W2153113253","https://openalex.org/W2154697573","https://openalex.org/W2178512749","https://openalex.org/W2255398506","https://openalex.org/W2467813275","https://openalex.org/W2515318112","https://openalex.org/W2580559781","https://openalex.org/W2764215565","https://openalex.org/W2767493192","https://openalex.org/W2800506573","https://openalex.org/W2806983257","https://openalex.org/W2898002359","https://openalex.org/W2913925629","https://openalex.org/W2923922145","https://openalex.org/W2937274403","https://openalex.org/W2950262541","https://openalex.org/W2965697058","https://openalex.org/W2971570110","https://openalex.org/W2979487778","https://openalex.org/W2982557070","https://openalex.org/W2999139721","https://openalex.org/W3007531339","https://openalex.org/W3010010399","https://openalex.org/W3111368838","https://openalex.org/W3113280799","https://openalex.org/W3114533066","https://openalex.org/W3122868809","https://openalex.org/W3124792448","https://openalex.org/W3142226569","https://openalex.org/W3189975020","https://openalex.org/W3211354089","https://openalex.org/W4220896689","https://openalex.org/W4224281833","https://openalex.org/W4225401197","https://openalex.org/W4284889206","https://openalex.org/W4294688359","https://openalex.org/W4297498015","https://openalex.org/W4307707398","https://openalex.org/W4311116298","https://openalex.org/W4321601845","https://openalex.org/W4379162241","https://openalex.org/W4385898424","https://openalex.org/W4386828252","https://openalex.org/W4389729803","https://openalex.org/W4391018049","https://openalex.org/W4391450294","https://openalex.org/W4391528430","https://openalex.org/W4393942528","https://openalex.org/W4395478479","https://openalex.org/W4396916382","https://openalex.org/W4411100487","https://openalex.org/W4411397270","https://openalex.org/W4412692211","https://openalex.org/W4412798178","https://openalex.org/W4414713894","https://openalex.org/W7123265126","https://openalex.org/W7125509679","https://openalex.org/W7125614102","https://openalex.org/W7131412564"],"related_works":["https://openalex.org/W2141443763","https://openalex.org/W2050909532","https://openalex.org/W1987521590","https://openalex.org/W1927501767","https://openalex.org/W1568660743","https://openalex.org/W2158489049","https://openalex.org/W1997221105","https://openalex.org/W1984202832","https://openalex.org/W1490647657","https://openalex.org/W4400179653"],"abstract_inverted_index":{"ABSTRACT":[0],"Cortical":[1],"neurons":[2,176,187,255],"integrate":[3],"from":[4,17],"a":[5,81,136,189,244],"wide":[6],"range":[7],"of":[8,28,52,85,123,146,166,193,198,228,247,251,253,260],"synaptic":[9,241],"inputs,":[10],"locally":[11],"within":[12,160],"the":[13,24,31,119,163,182,196,199,223,248,257],"cortex":[14],"and":[15,26,40,91,105,154,211,232],"distally":[16],"multiple":[18],"brain":[19],"sources,":[20],"which":[21,98,131],"altogether":[22],"support":[23],"generation":[25],"transmission":[27,208],"spikes.":[29],"Yet,":[30],"relative":[32,67],"influence":[33],"on":[34],"local":[35,70],"cortical":[36,71,93,110,128,201,233,262],"processing":[37],"between":[38],"thalamocortical":[39,58,89,124,152,184,210,231,240],"intracortical":[41,61,157,161,212],"inputs":[42,220,242],"still":[43],"remains":[44],"poorly":[45],"understood.":[46],"Here,":[47],"we":[48,79,132,141,214],"used":[49],"tangential":[50],"insertion":[51],"high-density":[53],"silicon":[54],"probes":[55],"to":[56,60,69,118,134],"capture":[57],"next":[59],"functional":[62],"connectivity,":[63],"thereby":[64],"unraveling":[65],"their":[66],"contribution":[68],"dynamics.":[72],"By":[73],"comparing":[74],"wakefulness":[75],"versus":[76],"light":[77],"anesthesia,":[78],"revealed":[80],"marked":[82,190],"wakeful":[83,144,164,191,226,249],"increase":[84,97,192],"firing":[86,167,229,252],"in":[87,102,108,151,156,170,209,230],"specifically":[88],"axons":[90,125],"putative":[92,127],"inhibitory":[94,129,234,254],"neurons;":[95],"an":[96],"is":[99,116],"very":[100],"homogeneous":[101,225],"both":[103],"populations,":[104],"comparatively":[106],"absent":[107],"neighboring":[109],"excitatory":[111,186,200],"neurons.":[112,235],"Such":[113],"specific":[114],"comodulation":[115],"attributable":[117],"known":[120],"preferential":[121],"connectivity":[122],"toward":[126],"neurons,":[130,172],"quantified":[133],"follow":[135],"90/10%":[137],"preference.":[138],"In":[139,181],"addition,":[140],"uncovered":[142],"that":[143,216],"increases":[145,165,227],"activity":[147],"levels":[148],"are":[149],"symmetric":[150],"synapses":[153],"asymmetric":[155],"synapses.":[158],"Indeed,":[159],"synapses,":[162],"mostly":[168],"happen":[169],"receiving":[171,185],"leaving":[173],"pre-synaptic":[174],"upstream":[175],"barely":[177],"impacted":[178],"by":[179],"wakefulness.":[180],"meantime,":[183],"exhibit":[188],"firing,":[194],"unlike":[195],"rest":[197],"population.":[202],"Using":[203],"mathematical":[204],"modelling":[205],"simulating":[206],"spike":[207],"networks,":[213],"showed":[215],"only":[217],"outnumbering":[218],"thalamocortical-to-intracortical":[219],"could":[221],"mimic":[222],"observed":[224],"Altogether,":[236],"our":[237],"results":[238],"identify":[239],"as":[243],"key":[245],"controller":[246],"level":[250],"at":[256],"first":[258],"relay":[259],"visual":[261],"processing.":[263]},"counts_by_year":[],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2026-10-17T00:00:00"}
