{"id":"https://openalex.org/W7222245449","doi":"https://doi.org/10.1039/d6cb00109b","title":"Solution structure of a peptide-conjugated aggregation-induced-emission (AIE) fluorophore bound to a protein","display_name":"Solution structure of a peptide-conjugated aggregation-induced-emission (AIE) fluorophore bound to a protein","publication_year":2026,"publication_date":"2026-01-01","ids":{"openalex":"https://openalex.org/W7222245449","doi":"https://doi.org/10.1039/d6cb00109b","pmid":"https://pubmed.ncbi.nlm.nih.gov/42889470","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/13670144"},"language":"en","primary_location":{"id":"doi:10.1039/d6cb00109b","doi":"https://doi.org/10.1039/d6cb00109b","is_oa":true,"landing_page_url":"https://doi.org/10.1039/d6cb00109b","pdf_url":null,"source":{"id":"https://openalex.org/S4210222191","display_name":"RSC Chemical Biology","issn_l":"2633-0679","issn":["2633-0679"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","jufo-1","ki-jl-1","norway-1","oarl","poland-20","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320556","host_organization_name":"Royal Society of Chemistry","host_organization_lineage":["https://openalex.org/P4310320556"],"host_organization_lineage_names":["Royal Society of Chemistry"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"RSC Chemical Biology","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://doi.org/10.1039/d6cb00109b","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5158828256","display_name":"Daniel Seifert","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I62318514","display_name":"University of Duisburg-Essen","ror":"https://ror.org/04mz5ra38","country_code":"DE","type":"education","lineage":["https://openalex.org/I62318514"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Daniel Seifert","raw_affiliation_strings":["Structural and Medicinal Biochemistry, University of Duisburg-Essen, Essen, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Structural and Medicinal Biochemistry, University of Duisburg-Essen, Essen, Germany","institution_ids":["https://openalex.org/I62318514"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5046213653","display_name":"Matthias Hayduk","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I62318514","display_name":"University of Duisburg-Essen","ror":"https://ror.org/04mz5ra38","country_code":"DE","type":"education","lineage":["https://openalex.org/I62318514"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Matthias Hayduk","raw_affiliation_strings":["Faculty of Chemistry (Organic Chemistry), University of Duisburg-Essen, Essen, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Faculty of Chemistry (Organic Chemistry), University of Duisburg-Essen, Essen, Germany","institution_ids":["https://openalex.org/I62318514"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5024081162","display_name":"Torsten Herrmann","orcid":"https://orcid.org/0000-0003-2115-4781","observed_orcids":["https://orcid.org/0000-0003-2115-4781"]},"institutions":[{"id":"https://openalex.org/I4210152516","display_name":"Institut de Biologie Structurale","ror":"https://ror.org/04szabx38","country_code":"FR","type":"facility","lineage":["https://openalex.org/I1294671590","https://openalex.org/I2738703131","https://openalex.org/I4210091409","https://openalex.org/I4210096427","https://openalex.org/I4210113668","https://openalex.org/I4210152516","https://openalex.org/I899635006"]},{"id":"https://openalex.org/I899635006","display_name":"Universit\u00e9 Grenoble Alpes","ror":"https://ror.org/02rx3b187","country_code":"FR","type":"education","lineage":["https://openalex.org/I899635006"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Torsten Herrmann","raw_affiliation_strings":["Institute of Structural Biology, Grenoble Alpes University, Grenoble, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Structural Biology, Grenoble Alpes University, Grenoble, France","institution_ids":["https://openalex.org/I4210152516","https://openalex.org/I899635006"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5077153685","display_name":"David Podlesainski","orcid":"https://orcid.org/0000-0002-1111-8042","observed_orcids":["https://orcid.org/0000-0002-1111-8042"]},"institutions":[{"id":"https://openalex.org/I62318514","display_name":"University of Duisburg-Essen","ror":"https://ror.org/04mz5ra38","country_code":"DE","type":"education","lineage":["https://openalex.org/I62318514"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"David Podlesainski","raw_affiliation_strings":["Chemical Biology, University of Duisburg-Essen, Essen, Germany"],"raw_orcid":"https://orcid.org/0000-0002-1111-8042","affiliations":[{"raw_affiliation_string":"Chemical Biology, University of Duisburg-Essen, Essen, Germany","institution_ids":["https://openalex.org/I62318514"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5158792693","display_name":"Jill Rohde","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I62318514","display_name":"University of Duisburg-Essen","ror":"https://ror.org/04mz5ra38","country_code":"DE","type":"education","lineage":["https://openalex.org/I62318514"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Jill Rohde","raw_affiliation_strings":["Structural and Medicinal Biochemistry, University of Duisburg-Essen, Essen, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Structural and Medicinal Biochemistry, University of Duisburg-Essen, Essen, Germany","institution_ids":["https://openalex.org/I62318514"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5044453542","display_name":"J\u00fcrgen Linders","orcid":"https://orcid.org/0000-0001-7275-9225","observed_orcids":["https://orcid.org/0000-0001-7275-9225"]},"institutions":[{"id":"https://openalex.org/I62318514","display_name":"University of Duisburg-Essen","ror":"https://ror.org/04mz5ra38","country_code":"DE","type":"education","lineage":["https://openalex.org/I62318514"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"J\u00fcrgen Linders","raw_affiliation_strings":["Physical Chemistry, University of Duisburg-Essen, Essen, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Physical Chemistry, University of Duisburg-Essen, Essen, Germany","institution_ids":["https://openalex.org/I62318514"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5024191146","display_name":"Markus Kaiser","orcid":"https://orcid.org/0000-0002-6540-8520","observed_orcids":["https://orcid.org/0000-0002-6540-8520"]},"institutions":[{"id":"https://openalex.org/I62318514","display_name":"University of Duisburg-Essen","ror":"https://ror.org/04mz5ra38","country_code":"DE","type":"education","lineage":["https://openalex.org/I62318514"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Markus Kaiser","raw_affiliation_strings":["Chemical Biology, University of Duisburg-Essen, Essen, Germany"],"raw_orcid":"https://orcid.org/0000-0002-6540-8520","affiliations":[{"raw_affiliation_string":"Chemical Biology, University of Duisburg-Essen, Essen, Germany","institution_ids":["https://openalex.org/I62318514"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5069695058","display_name":"Peter Bayer","orcid":"https://orcid.org/0000-0003-0435-7202","observed_orcids":["https://orcid.org/0000-0003-0435-7202"]},"institutions":[{"id":"https://openalex.org/I62318514","display_name":"University of Duisburg-Essen","ror":"https://ror.org/04mz5ra38","country_code":"DE","type":"education","lineage":["https://openalex.org/I62318514"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Peter Bayer","raw_affiliation_strings":["Structural and Medicinal Biochemistry, University of Duisburg-Essen, Essen, Germany"],"raw_orcid":"https://orcid.org/0000-0003-0435-7202","affiliations":[{"raw_affiliation_string":"Structural and Medicinal Biochemistry, University of Duisburg-Essen, Essen, Germany","institution_ids":["https://openalex.org/I62318514"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5019237165","display_name":"Jens Voskuhl","orcid":"https://orcid.org/0000-0002-9612-2306","observed_orcids":["https://orcid.org/0000-0002-9612-2306"]},"institutions":[{"id":"https://openalex.org/I62318514","display_name":"University of Duisburg-Essen","ror":"https://ror.org/04mz5ra38","country_code":"DE","type":"education","lineage":["https://openalex.org/I62318514"]}],"countries":["DE"],"is_corresponding":true,"raw_author_name":"Jens Voskuhl","raw_affiliation_strings":["Faculty of Chemistry (Organic Chemistry), University of Duisburg-Essen, Essen, Germany"],"raw_orcid":"https://orcid.org/0000-0002-9612-2306","affiliations":[{"raw_affiliation_string":"Faculty of Chemistry (Organic Chemistry), University of Duisburg-Essen, Essen, Germany","institution_ids":["https://openalex.org/I62318514"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5015679438","display_name":"Christine Beuck","orcid":"https://orcid.org/0000-0001-7513-7384","observed_orcids":["https://orcid.org/0000-0001-7513-7384"]},"institutions":[{"id":"https://openalex.org/I62318514","display_name":"University of Duisburg-Essen","ror":"https://ror.org/04mz5ra38","country_code":"DE","type":"education","lineage":["https://openalex.org/I62318514"]}],"countries":["DE"],"is_corresponding":true,"raw_author_name":"Christine Beuck","raw_affiliation_strings":["Structural and Medicinal Biochemistry, University of Duisburg-Essen, Essen, Germany"],"raw_orcid":"https://orcid.org/0000-0001-7513-7384","affiliations":[{"raw_affiliation_string":"Structural and Medicinal Biochemistry, University of Duisburg-Essen, Essen, Germany","institution_ids":["https://openalex.org/I62318514"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5015679438","https://openalex.org/A5019237165"],"corresponding_institution_ids":["https://openalex.org/I62318514"],"apc_list":{"value":1600,"currency":"GBP","value_usd":1962},"apc_paid":{"value":1600,"currency":"GBP","value_usd":1962},"fwci":0.0,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":{"value":0.60965276,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"7","issue":"11","first_page":"2299","last_page":"2308"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11240","display_name":"Luminescence and Fluorescent Materials","score":0.9794999957084656,"subfield":{"id":"https://openalex.org/subfields/2505","display_name":"Materials Chemistry"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T11240","display_name":"Luminescence and Fluorescent Materials","score":0.9794999957084656,"subfield":{"id":"https://openalex.org/subfields/2505","display_name":"Materials Chemistry"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10532","display_name":"Molecular Sensors and Ion Detection","score":0.006000000052154064,"subfield":{"id":"https://openalex.org/subfields/1607","display_name":"Spectroscopy"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10540","display_name":"Advanced Fluorescence Microscopy Techniques","score":0.0019000000320374966,"subfield":{"id":"https://openalex.org/subfields/1304","display_name":"Biophysics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/aggregation-induced-emission","display_name":"aggregation-induced emission","score":0.9980000257492065},{"id":"https://openalex.org/keywords/protein-peptide-interactions","display_name":"protein-peptide interactions","score":0.7149999737739563},{"id":"https://openalex.org/keywords/solution-structure","display_name":"solution structure","score":0.6299999952316284},{"id":"https://openalex.org/keywords/protein-recognition","display_name":"protein recognition","score":0.39100000262260437},{"id":"https://openalex.org/keywords/autofluorescence","display_name":"autofluorescence","score":0.8119999766349792},{"id":"https://openalex.org/keywords/peptide-length-effects","display_name":"peptide length effects","score":0.5830000042915344}],"concepts":[{"id":"https://openalex.org/C2778617687","wikidata":"https://www.wikidata.org/wiki/Q2448456","display_name":"Fluorophore","level":3,"score":0.7150999903678894},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.6776000261306763},{"id":"https://openalex.org/C91881484","wikidata":"https://www.wikidata.org/wiki/Q191807","display_name":"Fluorescence","level":2,"score":0.6625999808311462},{"id":"https://openalex.org/C112613896","wikidata":"https://www.wikidata.org/wiki/Q898370","display_name":"Conjugated system","level":3,"score":0.5631999969482422},{"id":"https://openalex.org/C2779281246","wikidata":"https://www.wikidata.org/wiki/Q172847","display_name":"Peptide","level":2,"score":0.4339999854564667},{"id":"https://openalex.org/C8010536","wikidata":"https://www.wikidata.org/wiki/Q160398","display_name":"Crystallography","level":1,"score":0.3596000075340271},{"id":"https://openalex.org/C47701112","wikidata":"https://www.wikidata.org/wiki/Q735188","display_name":"Protein structure","level":2,"score":0.34869998693466187},{"id":"https://openalex.org/C12554922","wikidata":"https://www.wikidata.org/wiki/Q7100","display_name":"Biophysics","level":1,"score":0.29649999737739563},{"id":"https://openalex.org/C2994041443","wikidata":"https://www.wikidata.org/wiki/Q5447188","display_name":"Chemical solution","level":2,"score":0.29330000281333923},{"id":"https://openalex.org/C158711907","wikidata":"https://www.wikidata.org/wiki/Q1768467","display_name":"Fluorescence spectroscopy","level":3,"score":0.28630000352859497},{"id":"https://openalex.org/C66974803","wikidata":"https://www.wikidata.org/wiki/Q10359898","display_name":"Nuclear magnetic resonance spectroscopy","level":2,"score":0.27390000224113464}],"mesh":[],"locations_count":5,"locations":[{"id":"doi:10.1039/d6cb00109b","doi":"https://doi.org/10.1039/d6cb00109b","is_oa":true,"landing_page_url":"https://doi.org/10.1039/d6cb00109b","pdf_url":null,"source":{"id":"https://openalex.org/S4210222191","display_name":"RSC Chemical Biology","issn_l":"2633-0679","issn":["2633-0679"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","jufo-1","ki-jl-1","norway-1","oarl","poland-20","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320556","host_organization_name":"Royal Society of Chemistry","host_organization_lineage":["https://openalex.org/P4310320556"],"host_organization_lineage_names":["Royal Society of Chemistry"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"RSC Chemical Biology","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:13670144","doi":null,"is_oa":true,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/42889470/","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC13670144/pdf/CB-OLF-D6CB00109B.pdf","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"RSC Chem Biol","raw_type":"Text"},{"id":"pmid:42889470","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/42889470","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"RSC chemical biology","raw_type":"Journal Article"},{"id":"pmh:oai:bibliographie.ub.uni-due.de:ubo_mods_00247979","doi":null,"is_oa":false,"landing_page_url":"https://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&origin=inward&scp=105053400024","pdf_url":null,"source":{"id":"https://openalex.org/S7407055102","display_name":"Universit\u00e4tsbibliographie, Universit\u00e4t Duisburg-Essen","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"article"},{"id":"pmh:oai:doaj.org/article:24f58b72b169476fb4d5e06b92f62f03","doi":null,"is_oa":false,"landing_page_url":"https://doaj.org/article/24f58b72b169476fb4d5e06b92f62f03","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"RSC Chemical Biology, Vol 7, Iss 11, Pp 2299-2299 (2026)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.1039/d6cb00109b","doi":"https://doi.org/10.1039/d6cb00109b","is_oa":true,"landing_page_url":"https://doi.org/10.1039/d6cb00109b","pdf_url":null,"source":{"id":"https://openalex.org/S4210222191","display_name":"RSC Chemical Biology","issn_l":"2633-0679","issn":["2633-0679"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","jufo-1","ki-jl-1","norway-1","oarl","poland-20","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320556","host_organization_name":"Royal Society of Chemistry","host_organization_lineage":["https://openalex.org/P4310320556"],"host_organization_lineage_names":["Royal Society of Chemistry"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"RSC Chemical Biology","raw_type":"journal-article"},"sustainable_development_goals":[],"study_designs":[],"awards":[{"id":"https://openalex.org/G1743581083","display_name":null,"funder_award_id":"CRC 1093","funder_id":"https://openalex.org/F4320320879","funder_display_name":"Deutsche Forschungsgemeinschaft"},{"id":"https://openalex.org/G9001303099","display_name":null,"funder_award_id":"INST 20876/495-1","funder_id":"https://openalex.org/F4320320879","funder_display_name":"Deutsche Forschungsgemeinschaft"},{"id":"https://openalex.org/G9001303876","display_name":null,"funder_award_id":"INST 20876/372-1","funder_id":"https://openalex.org/F4320320879","funder_display_name":"Deutsche Forschungsgemeinschaft"}],"funders":[{"id":"https://openalex.org/F4320320879","display_name":"Deutsche Forschungsgemeinschaft","ror":"https://ror.org/018mejw64"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W7222245449.pdf","grobid_xml":"https://content.openalex.org/works/W7222245449.grobid-xml"},"referenced_works_count":56,"referenced_works":["https://openalex.org/W72907974","https://openalex.org/W1522143782","https://openalex.org/W1963676212","https://openalex.org/W1964272884","https://openalex.org/W1967163463","https://openalex.org/W1984990803","https://openalex.org/W2004925055","https://openalex.org/W2012871864","https://openalex.org/W2021226373","https://openalex.org/W2032185182","https://openalex.org/W2033416116","https://openalex.org/W2035503835","https://openalex.org/W2043885312","https://openalex.org/W2050779639","https://openalex.org/W2068486719","https://openalex.org/W2074278124","https://openalex.org/W2089390251","https://openalex.org/W2094991239","https://openalex.org/W2113675798","https://openalex.org/W2119117290","https://openalex.org/W2125059729","https://openalex.org/W2139936160","https://openalex.org/W2143791437","https://openalex.org/W2149200290","https://openalex.org/W2266320077","https://openalex.org/W2332044748","https://openalex.org/W2728759441","https://openalex.org/W2744329338","https://openalex.org/W2791996520","https://openalex.org/W2811498567","https://openalex.org/W2887040277","https://openalex.org/W2903028026","https://openalex.org/W2906838946","https://openalex.org/W2948334193","https://openalex.org/W2966155083","https://openalex.org/W3004934154","https://openalex.org/W3042602012","https://openalex.org/W3049004397","https://openalex.org/W3119682294","https://openalex.org/W3134386439","https://openalex.org/W3156094766","https://openalex.org/W3193038869","https://openalex.org/W4200136444","https://openalex.org/W4220840464","https://openalex.org/W4297007959","https://openalex.org/W4308934385","https://openalex.org/W4313907718","https://openalex.org/W4316115300","https://openalex.org/W4321780682","https://openalex.org/W4381999304","https://openalex.org/W4387665886","https://openalex.org/W4388658985","https://openalex.org/W4400289289","https://openalex.org/W4401035908","https://openalex.org/W4404565402","https://openalex.org/W4410287219"],"related_works":["https://openalex.org/W6962745810","https://openalex.org/W1974052969","https://openalex.org/W2906838946","https://openalex.org/W2041390593","https://openalex.org/W2193351087","https://openalex.org/W2914665311","https://openalex.org/W3092494435","https://openalex.org/W7024636522","https://openalex.org/W2902104369","https://openalex.org/W4205512959"],"abstract_inverted_index":{"Here,":[0],"we":[1],"present":[2],"a":[3,37,45,50,74,98,118,124],"class":[4],"of":[5,20,30,40,76,107,117,131,135,164],"peptide-conjugated":[6],"fluorophores":[7,57],"based":[8],"on":[9],"aromatic":[10,133,162],"thioethers":[11],"with":[12,86,156,170],"aggregation-induced":[13],"emission":[14],"(AIE)":[15],"properties":[16,70],"for":[17,63],"specific":[18,64],"recognition":[19,159],"small":[21],"proteins":[22],"and":[23,68,79,111,178],"also":[24],"the":[25,41,105,108,115,120,132,136,145,151,165,171,182],"first":[26],"solution":[27],"NMR":[28],"structure":[29],"an":[31,83,91],"AIE":[32,84],"ligand":[33],"specifically":[34],"bound":[35],"to":[36,103,154],"protein.":[38],"Binding":[39],"hPin1-WW":[42,152],"domain":[43,153],"as":[44,59,73],"model":[46],"protein":[47,65,96,172],"resulted":[48],"in":[49,140,181],"significant":[51],"fluorescence":[52,93,184],"increase,":[53],"making":[54],"these":[55],"AIE-peptide":[56,110,121,146],"suitable":[58],"direct":[60],"readout":[61],"probes":[62],"interactions.":[66],"Autofluorescence":[67],"protein-binding":[69],"were":[71],"elucidated":[72],"function":[75],"peptide":[77,158],"length":[78],"fluorophore":[80,85],"concentration.":[81],"While":[82],"two":[87],"conjugated":[88],"peptides":[89],"shows":[90,123],"enhanced":[92],"increase":[94],"upon":[95,148],"binding,":[97,149],"one-armed":[99],"derivative":[100],"enabled":[101],"us":[102],"solve":[104],"structures":[106],"free":[109],"its":[112,157],"complex.":[113],"In":[114,143],"absence":[116],"protein,":[119],"conjugate":[122],"curled-up":[125],"conformation":[126],"that":[127],"still":[128],"allows":[129],"rotation":[130],"rings":[134,163],"AIE-core,":[137],"thus":[138,179],"resulting":[139],"low":[141],"auto-fluorescence.":[142],"contrast,":[144],"unfurls":[147],"allowing":[150],"interact":[155],"sequence.":[160],"The":[161],"AIE-core":[166],"form":[167],"additional":[168],"contacts":[169],"surface,":[173],"which":[174],"restricts":[175],"their":[176],"motions":[177],"results":[180],"observed":[183],"increase.":[185]},"counts_by_year":[],"updated_date":"2026-11-08T12:12:28.789561","created_date":"2026-10-16T00:00:00"}
