{"id":"https://openalex.org/W7221785230","doi":"https://doi.org/10.1016/j.ctro.2026.101318","title":"Longitudinal tumor response dynamics after staged gamma knife radiosurgery combined with bevacizumab in sporadic vestibular schwannoma","display_name":"Longitudinal tumor response dynamics after staged gamma knife radiosurgery combined with bevacizumab in sporadic vestibular schwannoma","publication_year":2026,"publication_date":"2026-10-14","ids":{"openalex":"https://openalex.org/W7221785230","doi":"https://doi.org/10.1016/j.ctro.2026.101318","pmid":"https://pubmed.ncbi.nlm.nih.gov/42936495","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/13698073"},"language":"en","primary_location":{"id":"doi:10.1016/j.ctro.2026.101318","doi":"https://doi.org/10.1016/j.ctro.2026.101318","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.ctro.2026.101318","pdf_url":"https://www.ctro.science/article/S2405-6308(26)00213-2/pdf","source":{"id":"https://openalex.org/S2898297225","display_name":"Clinical and Translational Radiation Oncology","issn_l":"2405-6308","issn":["2405-6308"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","doyens","jufo-1","ki-jl-1","norway-1","oarl","poland-20","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Clinical and Translational Radiation Oncology","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://www.ctro.science/article/S2405-6308(26)00213-2/pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5158710333","display_name":"Zeyu Peng","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I183067930","display_name":"Shanghai Jiao Tong University","ror":"https://ror.org/0220qvk04","country_code":"CN","type":"education","lineage":["https://openalex.org/I183067930"]},{"id":"https://openalex.org/I2801556517","display_name":"Ruijin Hospital","ror":"https://ror.org/01hv94n30","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I2801556517"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Zeyu Peng","raw_affiliation_strings":["Department of Neurosurgery, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurosurgery, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China","institution_ids":["https://openalex.org/I183067930","https://openalex.org/I2801556517"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5158702194","display_name":"Shangbo Wang","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I183067930","display_name":"Shanghai Jiao Tong University","ror":"https://ror.org/0220qvk04","country_code":"CN","type":"education","lineage":["https://openalex.org/I183067930"]},{"id":"https://openalex.org/I2801556517","display_name":"Ruijin Hospital","ror":"https://ror.org/01hv94n30","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I2801556517"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Shangbo Wang","raw_affiliation_strings":["Department of Neurosurgery, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurosurgery, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China","institution_ids":["https://openalex.org/I183067930","https://openalex.org/I2801556517"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5040490331","display_name":"Jiaojiao Cao","orcid":"https://orcid.org/0000-0001-9839-2767","observed_orcids":["https://orcid.org/0000-0001-9839-2767"]},"institutions":[{"id":"https://openalex.org/I183067930","display_name":"Shanghai Jiao Tong University","ror":"https://ror.org/0220qvk04","country_code":"CN","type":"education","lineage":["https://openalex.org/I183067930"]},{"id":"https://openalex.org/I2801556517","display_name":"Ruijin Hospital","ror":"https://ror.org/01hv94n30","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I2801556517"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Jiao-jiao Cao","raw_affiliation_strings":["Department of Neurosurgery, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurosurgery, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China","institution_ids":["https://openalex.org/I183067930","https://openalex.org/I2801556517"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5158701768","display_name":"Hongchi Zhang","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I183067930","display_name":"Shanghai Jiao Tong University","ror":"https://ror.org/0220qvk04","country_code":"CN","type":"education","lineage":["https://openalex.org/I183067930"]},{"id":"https://openalex.org/I2801556517","display_name":"Ruijin Hospital","ror":"https://ror.org/01hv94n30","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I2801556517"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Hongchi Zhang","raw_affiliation_strings":["Department of Neurosurgery, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurosurgery, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China","institution_ids":["https://openalex.org/I183067930","https://openalex.org/I2801556517"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5158753915","display_name":"Jin Yang","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I183067930","display_name":"Shanghai Jiao Tong University","ror":"https://ror.org/0220qvk04","country_code":"CN","type":"education","lineage":["https://openalex.org/I183067930"]},{"id":"https://openalex.org/I2801556517","display_name":"Ruijin Hospital","ror":"https://ror.org/01hv94n30","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I2801556517"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Jin Yang","raw_affiliation_strings":["Department of Pulmonary and Critical Care Medicine, Ruijin Hospital, Shanghai Jiao Tong University, School of Medicine, Shanghai, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pulmonary and Critical Care Medicine, Ruijin Hospital, Shanghai Jiao Tong University, School of Medicine, Shanghai, China","institution_ids":["https://openalex.org/I183067930","https://openalex.org/I2801556517"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5032142225","display_name":"Liangyun Hu","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I183067930","display_name":"Shanghai Jiao Tong University","ror":"https://ror.org/0220qvk04","country_code":"CN","type":"education","lineage":["https://openalex.org/I183067930"]},{"id":"https://openalex.org/I2801556517","display_name":"Ruijin Hospital","ror":"https://ror.org/01hv94n30","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I2801556517"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Liang-Yun Hu","raw_affiliation_strings":["Department of Neurosurgery, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurosurgery, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China","institution_ids":["https://openalex.org/I183067930","https://openalex.org/I2801556517"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5158736013","display_name":"Ran-ran Dai","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I183067930","display_name":"Shanghai Jiao Tong University","ror":"https://ror.org/0220qvk04","country_code":"CN","type":"education","lineage":["https://openalex.org/I183067930"]},{"id":"https://openalex.org/I2801556517","display_name":"Ruijin Hospital","ror":"https://ror.org/01hv94n30","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I2801556517"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Ran-ran Dai","raw_affiliation_strings":["Department of Pulmonary and Critical Care Medicine, Ruijin Hospital, Shanghai Jiao Tong University, School of Medicine, Shanghai, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pulmonary and Critical Care Medicine, Ruijin Hospital, Shanghai Jiao Tong University, School of Medicine, Shanghai, China","institution_ids":["https://openalex.org/I183067930","https://openalex.org/I2801556517"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110797913","display_name":"Si\u2010Jian Pan","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I183067930","display_name":"Shanghai Jiao Tong University","ror":"https://ror.org/0220qvk04","country_code":"CN","type":"education","lineage":["https://openalex.org/I183067930"]},{"id":"https://openalex.org/I2801556517","display_name":"Ruijin Hospital","ror":"https://ror.org/01hv94n30","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I2801556517"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Si-Jian Pan","raw_affiliation_strings":["Department of Neurosurgery, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurosurgery, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China","institution_ids":["https://openalex.org/I183067930","https://openalex.org/I2801556517"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5070861479","display_name":"Chengjie Qiu","orcid":"https://orcid.org/0000-0002-5382-8325","observed_orcids":["https://orcid.org/0000-0002-5382-8325"]},"institutions":[{"id":"https://openalex.org/I183067930","display_name":"Shanghai Jiao Tong University","ror":"https://ror.org/0220qvk04","country_code":"CN","type":"education","lineage":["https://openalex.org/I183067930"]},{"id":"https://openalex.org/I2801556517","display_name":"Ruijin Hospital","ror":"https://ror.org/01hv94n30","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I2801556517"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Cheng-Jie Qiu","raw_affiliation_strings":["Department of Neurosurgery, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurosurgery, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China","institution_ids":["https://openalex.org/I183067930","https://openalex.org/I2801556517"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5070861479","https://openalex.org/A5110797913"],"corresponding_institution_ids":["https://openalex.org/I183067930","https://openalex.org/I2801556517"],"apc_list":{"value":2430,"currency":"USD","value_usd":2430},"apc_paid":{"value":2430,"currency":"USD","value_usd":2430},"fwci":0.0,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":{"value":0.82219822,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"62","issue":null,"first_page":"101318","last_page":"101318"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11251","display_name":"Meningioma and schwannoma management","score":0.9951000213623047,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11251","display_name":"Meningioma and schwannoma management","score":0.9951000213623047,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10832","display_name":"Pituitary Gland Disorders and Treatments","score":0.0006000000284984708,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11054","display_name":"Adrenal and Paraganglionic Tumors","score":0.0005000000237487257,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/vestibular-schwannoma","display_name":"vestibular schwannoma","score":0.984000027179718},{"id":"https://openalex.org/keywords/gamma-knife-radiosurgery","display_name":"gamma knife radiosurgery","score":0.9150000214576721},{"id":"https://openalex.org/keywords/bevacizumab","display_name":"bevacizumab","score":0.906000018119812},{"id":"https://openalex.org/keywords/staged-treatment","display_name":"staged treatment","score":0.5590000152587891},{"id":"https://openalex.org/keywords/anti-vegf-therapy","display_name":"anti-VEGF therapy","score":0.6240000128746033}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8956000208854675},{"id":"https://openalex.org/C2781447767","wikidata":"https://www.wikidata.org/wiki/Q369148","display_name":"Schwannoma","level":2,"score":0.7942000031471252},{"id":"https://openalex.org/C2777802072","wikidata":"https://www.wikidata.org/wiki/Q413299","display_name":"Bevacizumab","level":3,"score":0.75},{"id":"https://openalex.org/C2780387249","wikidata":"https://www.wikidata.org/wiki/Q973234","display_name":"Radiosurgery","level":3,"score":0.7394999861717224},{"id":"https://openalex.org/C126838900","wikidata":"https://www.wikidata.org/wiki/Q77604","display_name":"Radiology","level":1,"score":0.5356000065803528},{"id":"https://openalex.org/C2994042627","wikidata":"https://www.wikidata.org/wiki/Q973234","display_name":"Gamma knife","level":4,"score":0.46149998903274536},{"id":"https://openalex.org/C190041318","wikidata":"https://www.wikidata.org/wiki/Q596832","display_name":"Vestibular system","level":2,"score":0.43059998750686646},{"id":"https://openalex.org/C2776651944","wikidata":"https://www.wikidata.org/wiki/Q1147165","display_name":"Cyberknife","level":4,"score":0.3149999976158142},{"id":"https://openalex.org/C187625094","wikidata":"https://www.wikidata.org/wiki/Q7388452","display_name":"SABR volatility model","level":4,"score":0.3077000081539154},{"id":"https://openalex.org/C509974204","wikidata":"https://www.wikidata.org/wiki/Q180507","display_name":"Radiation therapy","level":2,"score":0.30250000953674316},{"id":"https://openalex.org/C2989005","wikidata":"https://www.wikidata.org/wiki/Q214963","display_name":"Nuclear medicine","level":1,"score":0.30169999599456787},{"id":"https://openalex.org/C2778679214","wikidata":"https://www.wikidata.org/wiki/Q1935832","display_name":"Neurofibromatosis type 2","level":3,"score":0.2976999878883362},{"id":"https://openalex.org/C2780858735","wikidata":"https://www.wikidata.org/wiki/Q423965","display_name":"Acoustic neuroma","level":2,"score":0.2793999910354614},{"id":"https://openalex.org/C2908761598","wikidata":"https://www.wikidata.org/wiki/Q3488638","display_name":"Positron Emission Tomography-Computed Tomography","level":3,"score":0.2578999996185303},{"id":"https://openalex.org/C2779281540","wikidata":"https://www.wikidata.org/wiki/Q5062122","display_name":"Central nervous system disease","level":2,"score":0.25519999861717224},{"id":"https://openalex.org/C2778934081","wikidata":"https://www.wikidata.org/wiki/Q1981345","display_name":"Neuroma","level":2,"score":0.2549000084400177},{"id":"https://openalex.org/C145912823","wikidata":"https://www.wikidata.org/wiki/Q113558","display_name":"Dynamics (music)","level":2,"score":0.2533000111579895}],"mesh":[],"locations_count":4,"locations":[{"id":"doi:10.1016/j.ctro.2026.101318","doi":"https://doi.org/10.1016/j.ctro.2026.101318","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.ctro.2026.101318","pdf_url":"https://www.ctro.science/article/S2405-6308(26)00213-2/pdf","source":{"id":"https://openalex.org/S2898297225","display_name":"Clinical and Translational Radiation Oncology","issn_l":"2405-6308","issn":["2405-6308"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","doyens","jufo-1","ki-jl-1","norway-1","oarl","poland-20","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Clinical and Translational Radiation Oncology","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:13698073","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC13698073/","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC13698073/pdf/main.pdf","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Clin Transl Radiat Oncol","raw_type":"Text"},{"id":"pmid:42936495","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/42936495","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Clinical and translational radiation oncology","raw_type":"Journal Article"},{"id":"pmh:oai:doaj.org/article:122abf6811ff4add8ee40a26544e02be","doi":null,"is_oa":false,"landing_page_url":"https://doaj.org/article/122abf6811ff4add8ee40a26544e02be","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Clinical and Translational Radiation Oncology, Vol 62, Iss , Pp 101318- (2027)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.1016/j.ctro.2026.101318","doi":"https://doi.org/10.1016/j.ctro.2026.101318","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.ctro.2026.101318","pdf_url":"https://www.ctro.science/article/S2405-6308(26)00213-2/pdf","source":{"id":"https://openalex.org/S2898297225","display_name":"Clinical and Translational Radiation Oncology","issn_l":"2405-6308","issn":["2405-6308"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","doyens","jufo-1","ki-jl-1","norway-1","oarl","poland-20","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Clinical and Translational Radiation Oncology","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":1.0}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W7221785230.pdf","grobid_xml":"https://content.openalex.org/works/W7221785230.grobid-xml"},"referenced_works_count":23,"referenced_works":["https://openalex.org/W1975105301","https://openalex.org/W1990143919","https://openalex.org/W2013970861","https://openalex.org/W2018161909","https://openalex.org/W2170249858","https://openalex.org/W2170554416","https://openalex.org/W2293809486","https://openalex.org/W2794184867","https://openalex.org/W2889084541","https://openalex.org/W2941691447","https://openalex.org/W2953688818","https://openalex.org/W2970929853","https://openalex.org/W2981209726","https://openalex.org/W2982067290","https://openalex.org/W3085200879","https://openalex.org/W3107425853","https://openalex.org/W3128589524","https://openalex.org/W4205574973","https://openalex.org/W4295073966","https://openalex.org/W4362506515","https://openalex.org/W4383872499","https://openalex.org/W4385442832","https://openalex.org/W7162324218"],"related_works":["https://openalex.org/W4295073966","https://openalex.org/W2344234294","https://openalex.org/W2944962460","https://openalex.org/W2334547552","https://openalex.org/W2586876342","https://openalex.org/W2402578492","https://openalex.org/W4416141542","https://openalex.org/W2901835507","https://openalex.org/W3011111207","https://openalex.org/W1727822242"],"abstract_inverted_index":{"Background":[0],"Vestibular":[1],"schwannomas":[2],"(VSs)":[3],"are":[4],"benign":[5],"tumors":[6],"of":[7,157,173,216],"the":[8,241],"eighth":[9],"cranial":[10],"nerve.":[11],"Although":[12],"Gamma":[13],"Knife":[14],"radiosurgery":[15],"(GKRS)":[16],"achieves":[17],"durable":[18],"tumor":[19,36,43,85,134,183,210,225],"control,":[20],"delayed":[21],"regression":[22,211],"and":[23,46,55,78,104,130,196,212,227],"pseudoprogression":[24],"remain":[25],"clinical":[26,47],"challenges.":[27],"Staged":[28,199],"GKRS":[29,51,57,75,82,112,115,200],"combined":[30,52,201],"with":[31,53,68,73,80,111,128,188,202,206,232],"bevacizumab":[32,54,77,117,203],"may":[33],"alter":[34],"post-radiosurgical":[35],"response":[37,121],"patterns.":[38],"Aim":[39],"To":[40],"compare":[41],"longitudinal":[42],"response,":[44],"pseudoprogression,":[45],"outcomes":[48],"between":[49],"staged":[50,74,114],"single-session":[56,81],"alone":[58],"in":[59,153,169,220],"sporadic":[60,69,221],"VSs.":[61,222],"Methods":[62],"We":[63],"retrospectively":[64],"reviewed":[65],"72":[66],"patients":[67,158],"VSs:":[70],"49":[71],"treated":[72],"plus":[76,116],"23":[79],"alone.":[83],"Longitudinal":[84],"volume":[86,226],"changes":[87],"were":[88,194,230],"analyzed":[89],"using":[90,101],"multivariable":[91],"linear":[92],"mixed-effects":[93],"models,":[94],"while":[95],"early":[96,217],"volumetric":[97,149],"enlargement":[98,150,219],"was":[99,136,185,204,236,243],"evaluated":[100],"Kaplan-Meier":[102],"estimates":[103],"Cox":[105],"proportional":[106],"hazards":[107],"models.":[108],"Results":[109],"Compared":[110],"alone,":[113],"showed":[118],"significantly":[119],"different":[120],"trajectories":[122],"(treatment-by-time":[123],"interaction,":[124],"P":[125,145,164,179],"<":[126,146,165],"0.001),":[127],"earlier":[129],"sustained":[131,209],"regression.":[132,190,234],"Greater":[133],"reduction":[135],"observed":[137],"from":[138],"3":[139],"to":[140],"36":[141],"months":[142],"(all":[143],"adjusted":[144],"0.05).":[147],"Early":[148],"(>10%)":[151],"occurred":[152,168],"14.3%":[154],"versus":[155,171],"60.9%":[156],"(HR,":[159],"0.16;":[160],"95%":[161],"CI,":[162],"0.06\u20130.40;":[163],"0.001).":[166],"Pseudoprogression":[167,235],"4.1%":[170],"17.4%":[172],"patients,":[174],"without":[175],"statistical":[176],"significance":[177],"(":[178],"=":[180],"0.078).":[181],"Cystic":[182],"composition":[184,229],"independently":[186],"associated":[187,205,231],"greater":[189,233],"BEV-related":[191],"adverse":[192],"events":[193],"mild":[195],"manageable.":[197],"Conclusion":[198],"earlier,":[207],"more":[208],"a":[213],"lower":[214],"risk":[215],"post-treatment":[218],"Larger":[223],"baseline":[224],"cystic":[228],"numerically":[237],"less":[238],"frequent,":[239],"although":[240],"difference":[242],"not":[244],"statistically":[245],"significant.":[246],"Trial":[247,252],"registration":[248],"ChiCTR2600131856":[249],"(Chinese":[250],"Clinical":[251],"Registry).":[253]},"counts_by_year":[],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2026-10-15T00:00:00"}