{"id":"https://openalex.org/W7221548741","doi":"https://doi.org/10.3390/nu18203326","title":"Associations Between Gut Microbiota Abundance, Dietary Purine Intake, and Fecal Short-Chain Fatty Acids Across the Clinical Spectrum of Hyperuricemia: A Cross-Sectional Study in Mexican Adults","display_name":"Associations Between Gut Microbiota Abundance, Dietary Purine Intake, and Fecal Short-Chain Fatty Acids Across the Clinical Spectrum of Hyperuricemia: A Cross-Sectional Study in Mexican Adults","publication_year":2026,"publication_date":"2026-10-10","ids":{"openalex":"https://openalex.org/W7221548741","doi":"https://doi.org/10.3390/nu18203326","pmid":"https://pubmed.ncbi.nlm.nih.gov/42942896","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/13708603"},"language":"en","primary_location":{"id":"doi:10.3390/nu18203326","doi":"https://doi.org/10.3390/nu18203326","is_oa":true,"landing_page_url":"https://doi.org/10.3390/nu18203326","pdf_url":null,"source":{"id":"https://openalex.org/S110785341","display_name":"Nutrients","issn_l":"2072-6643","issn":["2072-6643"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nutrients","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://doi.org/10.3390/nu18203326","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5059167117","display_name":"Alim Caelli Fuentes-Bello","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I8961855","display_name":"Universidad Nacional Aut\u00f3noma de M\u00e9xico","ror":"https://ror.org/01tmp8f25","country_code":"MX","type":"education","lineage":["https://openalex.org/I8961855"]}],"countries":["MX"],"is_corresponding":false,"raw_author_name":"Alim Caelli Fuentes-Bello","raw_affiliation_strings":["Posgrado en Ciencias Biol\u00f3gicas, Universidad Nacional Aut\u00f3noma de M\u00e9xico, Unidad de Posgrado, Edificio D, 1\u00b0 Piso, Circuito de Posgrados, Ciudad Universitaria, Coyoac\u00e1n, Mexico City 04510, Mexico"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Posgrado en Ciencias Biol\u00f3gicas, Universidad Nacional Aut\u00f3noma de M\u00e9xico, Unidad de Posgrado, Edificio D, 1\u00b0 Piso, Circuito de Posgrados, Ciudad Universitaria, Coyoac\u00e1n, Mexico City 04510, Mexico","institution_ids":["https://openalex.org/I8961855"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5158448600","display_name":"Karla Vanessa Guevara-Gonzalez","orcid":"https://orcid.org/0009-0006-6126-3666","observed_orcids":["https://orcid.org/0009-0006-6126-3666"]},"institutions":[{"id":"https://openalex.org/I4210124243","display_name":"Instituto Nacional de Rehabilitaci\u00f3n","ror":"https://ror.org/03734cd59","country_code":"MX","type":"facility","lineage":["https://openalex.org/I4210124243"]}],"countries":["MX"],"is_corresponding":false,"raw_author_name":"Karla Vanessa Guevara-Gonzalez","raw_affiliation_strings":["Laboratorio de Gerociencias, Instituto Nacional de Rehabilitaci\u00f3n Luis Guillermo Ibarra Ibarra, Calz M\u00e9xico-Xochimilco 289, Coapa, Col. Arenal de Guadalupe, Tlalpan, Mexico City 14389, Mexico"],"raw_orcid":"https://orcid.org/0009-0006-6126-3666","affiliations":[{"raw_affiliation_string":"Laboratorio de Gerociencias, Instituto Nacional de Rehabilitaci\u00f3n Luis Guillermo Ibarra Ibarra, Calz M\u00e9xico-Xochimilco 289, Coapa, Col. Arenal de Guadalupe, Tlalpan, Mexico City 14389, Mexico","institution_ids":["https://openalex.org/I4210124243"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5055468553","display_name":"Omar Granados\u2010Portillo","orcid":"https://orcid.org/0000-0002-9647-9487","observed_orcids":["https://orcid.org/0000-0002-9647-9487"]},"institutions":[{"id":"https://openalex.org/I4210097900","display_name":"Instituto Nacional de Ciencias M\u00e9dicas y Nutrici\u00f3n Salvador Zubir\u00e1n","ror":"https://ror.org/00xgvev73","country_code":"MX","type":"facility","lineage":["https://openalex.org/I4210095685","https://openalex.org/I4210097900","https://openalex.org/I4210128723"]}],"countries":["MX"],"is_corresponding":false,"raw_author_name":"Omar Granados-Portillo","raw_affiliation_strings":["Departamento de Fisiolog\u00eda de la Nutrici\u00f3n, Instituto Nacional de Ciencias, M\u00e9dicas y Nutrici\u00f3n Salvador Zubir\u00e1n, Mexico City 14080, Mexico"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departamento de Fisiolog\u00eda de la Nutrici\u00f3n, Instituto Nacional de Ciencias, M\u00e9dicas y Nutrici\u00f3n Salvador Zubir\u00e1n, Mexico City 14080, Mexico","institution_ids":["https://openalex.org/I4210097900"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5054066391","display_name":"Laura Gabriela S\u00e1nchez\u2010Lozada","orcid":"https://orcid.org/0000-0003-0348-9617","observed_orcids":["https://orcid.org/0000-0003-0348-9617"]},"institutions":[{"id":"https://openalex.org/I4210157394","display_name":"Instituto Nacional de Cardiolog\u00eda","ror":"https://ror.org/046e90j34","country_code":"MX","type":"facility","lineage":["https://openalex.org/I4210157394"]}],"countries":["MX"],"is_corresponding":false,"raw_author_name":"Laura Gabriela S\u00e1nchez-Lozada","raw_affiliation_strings":["Departamento de Fisiopatolog\u00eda Cardio-Renal, Instituto Nacional de Cardiolog\u00eda Ignacio Ch\u00e1vez, Juan Badiano 1, Belisario Dom\u00ednguez Secc 16, Tlalpan, Mexico City 14080, Mexico"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departamento de Fisiopatolog\u00eda Cardio-Renal, Instituto Nacional de Cardiolog\u00eda Ignacio Ch\u00e1vez, Juan Badiano 1, Belisario Dom\u00ednguez Secc 16, Tlalpan, Mexico City 14080, Mexico","institution_ids":["https://openalex.org/I4210157394"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5034050529","display_name":"Ricardo Jasso\u2010Ch\u00e1vez","orcid":"https://orcid.org/0000-0001-9455-4503","observed_orcids":["https://orcid.org/0000-0001-9455-4503"]},"institutions":[{"id":"https://openalex.org/I4210157394","display_name":"Instituto Nacional de Cardiolog\u00eda","ror":"https://ror.org/046e90j34","country_code":"MX","type":"facility","lineage":["https://openalex.org/I4210157394"]}],"countries":["MX"],"is_corresponding":false,"raw_author_name":"Ricardo Jasso-Ch\u00e1vez","raw_affiliation_strings":["Departamento de Fisiolog\u00eda, Instituto Nacional de Cardiolog\u00eda Ignacio Ch\u00e1vez, Juan Badiano 1, Belisario Dom\u00ednguez Secc 16, Tlalpan, Mexico City 14080, Mexico"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departamento de Fisiolog\u00eda, Instituto Nacional de Cardiolog\u00eda Ignacio Ch\u00e1vez, Juan Badiano 1, Belisario Dom\u00ednguez Secc 16, Tlalpan, Mexico City 14080, Mexico","institution_ids":["https://openalex.org/I4210157394"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5080187123","display_name":"David Galeana-Cadena","orcid":"https://orcid.org/0000-0003-1374-1361","observed_orcids":["https://orcid.org/0000-0003-1374-1361"]},"institutions":[{"id":"https://openalex.org/I4210124243","display_name":"Instituto Nacional de Rehabilitaci\u00f3n","ror":"https://ror.org/03734cd59","country_code":"MX","type":"facility","lineage":["https://openalex.org/I4210124243"]},{"id":"https://openalex.org/I4405267535","display_name":"Universidad de la Salud","ror":"https://ror.org/035m3y262","country_code":"MX","type":"education","lineage":["https://openalex.org/I4405267535"]}],"countries":["MX"],"is_corresponding":false,"raw_author_name":"David Galeana-Cadena","raw_affiliation_strings":["Laboratorio de Gerociencias, Instituto Nacional de Rehabilitaci\u00f3n Luis Guillermo Ibarra Ibarra, Calz M\u00e9xico-Xochimilco 289, Coapa, Col. Arenal de Guadalupe, Tlalpan, Mexico City 14389, Mexico","Universidad de la Salud (UNISA), Vasco de Quiroga 1345, Sta F\u00e9, \u00c1lvaro Obreg\u00f3n, Mexico City 01210, Mexico"],"raw_orcid":"https://orcid.org/0000-0003-1374-1361","affiliations":[{"raw_affiliation_string":"Laboratorio de Gerociencias, Instituto Nacional de Rehabilitaci\u00f3n Luis Guillermo Ibarra Ibarra, Calz M\u00e9xico-Xochimilco 289, Coapa, Col. Arenal de Guadalupe, Tlalpan, Mexico City 14389, Mexico","institution_ids":["https://openalex.org/I4210124243"]},{"raw_affiliation_string":"Universidad de la Salud (UNISA), Vasco de Quiroga 1345, Sta F\u00e9, \u00c1lvaro Obreg\u00f3n, Mexico City 01210, Mexico","institution_ids":["https://openalex.org/I4405267535"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5099072075","display_name":"Efren Altamirano-Molina","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210124243","display_name":"Instituto Nacional de Rehabilitaci\u00f3n","ror":"https://ror.org/03734cd59","country_code":"MX","type":"facility","lineage":["https://openalex.org/I4210124243"]}],"countries":["MX"],"is_corresponding":false,"raw_author_name":"Efr\u00e9n Altamirano-Molina","raw_affiliation_strings":["Servicio de Reumatolog\u00eda, Instituto Nacional de Rehabilitaci\u00f3n Luis Guillermo Ibarra Ibarra, Calz M\u00e9xico-Xochimilco 289, Coapa, Col. Arenal de Guadalupe, Tlalpan, Mexico City 14389, Mexico"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Servicio de Reumatolog\u00eda, Instituto Nacional de Rehabilitaci\u00f3n Luis Guillermo Ibarra Ibarra, Calz M\u00e9xico-Xochimilco 289, Coapa, Col. Arenal de Guadalupe, Tlalpan, Mexico City 14389, Mexico","institution_ids":["https://openalex.org/I4210124243"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5067767609","display_name":"Br\u00edgida Herrera-L\u00f3pez","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210124243","display_name":"Instituto Nacional de Rehabilitaci\u00f3n","ror":"https://ror.org/03734cd59","country_code":"MX","type":"facility","lineage":["https://openalex.org/I4210124243"]}],"countries":["MX"],"is_corresponding":false,"raw_author_name":"Br\u00edgida Herrera-L\u00f3pez","raw_affiliation_strings":["Laboratorio de Gerociencias, Instituto Nacional de Rehabilitaci\u00f3n Luis Guillermo Ibarra Ibarra, Calz M\u00e9xico-Xochimilco 289, Coapa, Col. Arenal de Guadalupe, Tlalpan, Mexico City 14389, Mexico"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratorio de Gerociencias, Instituto Nacional de Rehabilitaci\u00f3n Luis Guillermo Ibarra Ibarra, Calz M\u00e9xico-Xochimilco 289, Coapa, Col. Arenal de Guadalupe, Tlalpan, Mexico City 14389, Mexico","institution_ids":["https://openalex.org/I4210124243"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5051024019","display_name":"Laura Edith Mart\u00ednez-G\u00f3mez","orcid":"https://orcid.org/0000-0003-3198-1350","observed_orcids":["https://orcid.org/0000-0003-3198-1350"]},"institutions":[{"id":"https://openalex.org/I4210124243","display_name":"Instituto Nacional de Rehabilitaci\u00f3n","ror":"https://ror.org/03734cd59","country_code":"MX","type":"facility","lineage":["https://openalex.org/I4210124243"]}],"countries":["MX"],"is_corresponding":false,"raw_author_name":"Laura Edith Mart\u00ednez-G\u00f3mez","raw_affiliation_strings":["Laboratorio de Gerociencias, Instituto Nacional de Rehabilitaci\u00f3n Luis Guillermo Ibarra Ibarra, Calz M\u00e9xico-Xochimilco 289, Coapa, Col. Arenal de Guadalupe, Tlalpan, Mexico City 14389, Mexico"],"raw_orcid":"https://orcid.org/0000-0003-3198-1350","affiliations":[{"raw_affiliation_string":"Laboratorio de Gerociencias, Instituto Nacional de Rehabilitaci\u00f3n Luis Guillermo Ibarra Ibarra, Calz M\u00e9xico-Xochimilco 289, Coapa, Col. Arenal de Guadalupe, Tlalpan, Mexico City 14389, Mexico","institution_ids":["https://openalex.org/I4210124243"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5000130577","display_name":"Carlos Mart\u00ednez-Armenta","orcid":"https://orcid.org/0000-0003-0413-4930","observed_orcids":["https://orcid.org/0000-0003-0413-4930"]},"institutions":[{"id":"https://openalex.org/I4210124243","display_name":"Instituto Nacional de Rehabilitaci\u00f3n","ror":"https://ror.org/03734cd59","country_code":"MX","type":"facility","lineage":["https://openalex.org/I4210124243"]}],"countries":["MX"],"is_corresponding":false,"raw_author_name":"Carlos Mart\u00ednez-Armenta","raw_affiliation_strings":["Laboratorio de Gerociencias, Instituto Nacional de Rehabilitaci\u00f3n Luis Guillermo Ibarra Ibarra, Calz M\u00e9xico-Xochimilco 289, Coapa, Col. Arenal de Guadalupe, Tlalpan, Mexico City 14389, Mexico"],"raw_orcid":"https://orcid.org/0000-0003-0413-4930","affiliations":[{"raw_affiliation_string":"Laboratorio de Gerociencias, Instituto Nacional de Rehabilitaci\u00f3n Luis Guillermo Ibarra Ibarra, Calz M\u00e9xico-Xochimilco 289, Coapa, Col. Arenal de Guadalupe, Tlalpan, Mexico City 14389, Mexico","institution_ids":["https://openalex.org/I4210124243"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5077293570","display_name":"Luis Esa\u00fa L\u00f3pez-J\u00e1come","orcid":"https://orcid.org/0000-0001-7387-0937","observed_orcids":["https://orcid.org/0000-0001-7387-0937"]},"institutions":[{"id":"https://openalex.org/I4210124243","display_name":"Instituto Nacional de Rehabilitaci\u00f3n","ror":"https://ror.org/03734cd59","country_code":"MX","type":"facility","lineage":["https://openalex.org/I4210124243"]}],"countries":["MX"],"is_corresponding":false,"raw_author_name":"Luis Esa\u00fa L\u00f3pez-J\u00e1come","raw_affiliation_strings":["Laboratorio de Microbiolog\u00eda Cl\u00ednica, Instituto Nacional de Rehabilitaci\u00f3n Luis Guillermo Ibarra Ibarra, Calz M\u00e9xico-Xochimilco 289, Coapa, Col. Arenal de Guadalupe, Tlalpan, Mexico City 14389, Mexico"],"raw_orcid":"https://orcid.org/0000-0001-7387-0937","affiliations":[{"raw_affiliation_string":"Laboratorio de Microbiolog\u00eda Cl\u00ednica, Instituto Nacional de Rehabilitaci\u00f3n Luis Guillermo Ibarra Ibarra, Calz M\u00e9xico-Xochimilco 289, Coapa, Col. Arenal de Guadalupe, Tlalpan, Mexico City 14389, Mexico","institution_ids":["https://openalex.org/I4210124243"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5158493037","display_name":"Regina Matesanz S\u00e1nchez Azcona","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I210606318","display_name":"Universidad An\u00e1huac M\u00e9xico Sur","ror":"https://ror.org/057g08s23","country_code":"MX","type":"education","lineage":["https://openalex.org/I210606318"]},{"id":"https://openalex.org/I4210113355","display_name":"Universidad An\u00e1huac","ror":"https://ror.org/02z9t1k38","country_code":"MX","type":"education","lineage":["https://openalex.org/I4210113355"]}],"countries":["MX"],"is_corresponding":false,"raw_author_name":"Regina Matesanz S\u00e1nchez Azcona","raw_affiliation_strings":["Facultad de Ciencias de la Salud, Universidad An\u00e1huac Campus Sur, Av. de los Tanques 865, Torres de Potrero, \u00c1lvaro Obreg\u00f3n, Mexico City 01840, Mexico"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Facultad de Ciencias de la Salud, Universidad An\u00e1huac Campus Sur, Av. de los Tanques 865, Torres de Potrero, \u00c1lvaro Obreg\u00f3n, Mexico City 01840, Mexico","institution_ids":["https://openalex.org/I210606318","https://openalex.org/I4210113355"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5020321513","display_name":"Mireya Mart\u00ednez-Garc\u00eda","orcid":"https://orcid.org/0000-0002-2876-8500","observed_orcids":["https://orcid.org/0000-0002-2876-8500"]},"institutions":[{"id":"https://openalex.org/I8961855","display_name":"Universidad Nacional Aut\u00f3noma de M\u00e9xico","ror":"https://ror.org/01tmp8f25","country_code":"MX","type":"education","lineage":["https://openalex.org/I8961855"]}],"countries":["MX"],"is_corresponding":false,"raw_author_name":"Mireya Mart\u00ednez-Garc\u00eda","raw_affiliation_strings":["Dental Public Health Department, Division of Graduate Studies and Research, School of Dentistry, Univesidad Nacional Aut\u00f3noma de M\u00e9xico, Mexico City 04510, Mexico"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Dental Public Health Department, Division of Graduate Studies and Research, School of Dentistry, Univesidad Nacional Aut\u00f3noma de M\u00e9xico, Mexico City 04510, Mexico","institution_ids":["https://openalex.org/I8961855"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5067983526","display_name":"Luis Manuel Amezcua-Guerra","orcid":"https://orcid.org/0000-0002-6258-5732","observed_orcids":["https://orcid.org/0000-0002-6258-5732"]},"institutions":[{"id":"https://openalex.org/I4210157394","display_name":"Instituto Nacional de Cardiolog\u00eda","ror":"https://ror.org/046e90j34","country_code":"MX","type":"facility","lineage":["https://openalex.org/I4210157394"]}],"countries":["MX"],"is_corresponding":false,"raw_author_name":"Luis M. Amezcua-Guerra","raw_affiliation_strings":["Departamento de Inmunolog\u00eda, Instituto Nacional de Cardiolog\u00eda Ignacio Ch\u00e1vez, Juan Badiano 1, Belisario Dom\u00ednguez Secc 16, Tlalpan, Mexico City 14080, Mexico"],"raw_orcid":"https://orcid.org/0000-0002-6258-5732","affiliations":[{"raw_affiliation_string":"Departamento de Inmunolog\u00eda, Instituto Nacional de Cardiolog\u00eda Ignacio Ch\u00e1vez, Juan Badiano 1, Belisario Dom\u00ednguez Secc 16, Tlalpan, Mexico City 14080, Mexico","institution_ids":["https://openalex.org/I4210157394"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5071619690","display_name":"Guadalupe Obdulia Guti\u00e9rrez-Esparza","orcid":"https://orcid.org/0000-0003-0090-2701","observed_orcids":["https://orcid.org/0000-0003-0090-2701","https://orcid.org/0000-0001-9572-9846"]},"institutions":[{"id":"https://openalex.org/I4210157394","display_name":"Instituto Nacional de Cardiolog\u00eda","ror":"https://ror.org/046e90j34","country_code":"MX","type":"facility","lineage":["https://openalex.org/I4210157394"]},{"id":"https://openalex.org/I4210163111","display_name":"Secretar\u00eda de Ciencia, Humanidades, Tecnolog\u00eda e Innovaci\u00f3n","ror":"https://ror.org/059ex5q34","country_code":"MX","type":"government","lineage":["https://openalex.org/I4210163111"]}],"countries":["MX"],"is_corresponding":false,"raw_author_name":"Guadalupe Guti\u00e9rrez-Esparza","raw_affiliation_strings":["Investigadora por M\u00e9xico, Secretar\u00eda de Ciencia, Humanidades, Tecnolog\u00eda e Innovaci\u00f3n, Avenida Insurgentes Sur 1582, Cr\u00e9dito Constructor, Mexico City 03940, Mexico","Subdirecci\u00f3n de Investigaci\u00f3n, Instituto Nacional de Cardiolog\u00eda Ignacio Ch\u00e1vez, Juan Badiano 1, Belisario Dom\u00ednguez Secc 16, Tlalpan, Mexico City 14080, Mexico"],"raw_orcid":"https://orcid.org/0000-0003-0090-2701","affiliations":[{"raw_affiliation_string":"Investigadora por M\u00e9xico, Secretar\u00eda de Ciencia, Humanidades, Tecnolog\u00eda e Innovaci\u00f3n, Avenida Insurgentes Sur 1582, Cr\u00e9dito Constructor, Mexico City 03940, Mexico","institution_ids":["https://openalex.org/I4210163111"]},{"raw_affiliation_string":"Subdirecci\u00f3n de Investigaci\u00f3n, Instituto Nacional de Cardiolog\u00eda Ignacio Ch\u00e1vez, Juan Badiano 1, Belisario Dom\u00ednguez Secc 16, Tlalpan, Mexico City 14080, Mexico","institution_ids":["https://openalex.org/I4210157394"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5158521800","display_name":"Carlos Pineda","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210124243","display_name":"Instituto Nacional de Rehabilitaci\u00f3n","ror":"https://ror.org/03734cd59","country_code":"MX","type":"facility","lineage":["https://openalex.org/I4210124243"]}],"countries":["MX"],"is_corresponding":false,"raw_author_name":"Carlos Pineda","raw_affiliation_strings":["Direcci\u00f3n General, Instituto Nacional de Rehabilitaci\u00f3n Luis Guillermo Ibarra Ibarra, Calz M\u00e9xico-Xochimilco 289, Coapa, Col. Arenal de Guadalupe, Tlalpan, Mexico City 14389, Mexico"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Direcci\u00f3n General, Instituto Nacional de Rehabilitaci\u00f3n Luis Guillermo Ibarra Ibarra, Calz M\u00e9xico-Xochimilco 289, Coapa, Col. Arenal de Guadalupe, Tlalpan, Mexico City 14389, Mexico","institution_ids":["https://openalex.org/I4210124243"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5007846055","display_name":"Janitzia V\u00e1zquez\u2010Mellado","orcid":"https://orcid.org/0000-0001-6636-2301","observed_orcids":["https://orcid.org/0000-0001-6636-2301"]},"institutions":[{"id":"https://openalex.org/I2802421035","display_name":"Hospital General de M\u00e9xico","ror":"https://ror.org/01php1d31","country_code":"MX","type":"healthcare","lineage":["https://openalex.org/I2802421035","https://openalex.org/I4210095685"]}],"countries":["MX"],"is_corresponding":false,"raw_author_name":"Janitzia V\u00e1zquez-Mellado","raw_affiliation_strings":["Servicio de Reumatolog\u00eda, Hospital General de M\u00e9xico Eduardo Liceaga, Dr. Balmis 148, Doctores, Cuauht\u00e9moc, Mexico City 06720, Mexico"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Servicio de Reumatolog\u00eda, Hospital General de M\u00e9xico Eduardo Liceaga, Dr. Balmis 148, Doctores, Cuauht\u00e9moc, Mexico City 06720, Mexico","institution_ids":["https://openalex.org/I2802421035"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5030980297","display_name":"Alberto Gabriel L\u00f3pez-Reyes","orcid":"https://orcid.org/0000-0002-2575-2589","observed_orcids":["https://orcid.org/0000-0002-2575-2589"]},"institutions":[{"id":"https://openalex.org/I4210124243","display_name":"Instituto Nacional de Rehabilitaci\u00f3n","ror":"https://ror.org/03734cd59","country_code":"MX","type":"facility","lineage":["https://openalex.org/I4210124243"]}],"countries":["MX"],"is_corresponding":false,"raw_author_name":"Alberto G. L\u00f3pez-Reyes","raw_affiliation_strings":["Laboratorio de Gerociencias, Instituto Nacional de Rehabilitaci\u00f3n Luis Guillermo Ibarra Ibarra, Calz M\u00e9xico-Xochimilco 289, Coapa, Col. Arenal de Guadalupe, Tlalpan, Mexico City 14389, Mexico"],"raw_orcid":"https://orcid.org/0000-0002-2575-2589","affiliations":[{"raw_affiliation_string":"Laboratorio de Gerociencias, Instituto Nacional de Rehabilitaci\u00f3n Luis Guillermo Ibarra Ibarra, Calz M\u00e9xico-Xochimilco 289, Coapa, Col. Arenal de Guadalupe, Tlalpan, Mexico City 14389, Mexico","institution_ids":["https://openalex.org/I4210124243"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5090953579","display_name":"Gabriela Ang\u00e9lica Mart\u00ednez\u2010Nava","orcid":"https://orcid.org/0000-0001-9857-3840","observed_orcids":["https://orcid.org/0000-0001-9857-3840"]},"institutions":[{"id":"https://openalex.org/I4210124243","display_name":"Instituto Nacional de Rehabilitaci\u00f3n","ror":"https://ror.org/03734cd59","country_code":"MX","type":"facility","lineage":["https://openalex.org/I4210124243"]}],"countries":["MX"],"is_corresponding":true,"raw_author_name":"Gabriela Ang\u00e9lica Mart\u00ednez-Nava","raw_affiliation_strings":["Laboratorio de Gerociencias, Instituto Nacional de Rehabilitaci\u00f3n Luis Guillermo Ibarra Ibarra, Calz M\u00e9xico-Xochimilco 289, Coapa, Col. Arenal de Guadalupe, Tlalpan, Mexico City 14389, Mexico"],"raw_orcid":"https://orcid.org/0000-0001-9857-3840","affiliations":[{"raw_affiliation_string":"Laboratorio de Gerociencias, Instituto Nacional de Rehabilitaci\u00f3n Luis Guillermo Ibarra Ibarra, Calz M\u00e9xico-Xochimilco 289, Coapa, Col. Arenal de Guadalupe, Tlalpan, Mexico City 14389, Mexico","institution_ids":["https://openalex.org/I4210124243"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":9,"corresponding_author_ids":["https://openalex.org/A5090953579"],"corresponding_institution_ids":["https://openalex.org/I4210124243"],"apc_list":{"value":2900,"currency":"CHF","value_usd":3499},"apc_paid":{"value":2900,"currency":"CHF","value_usd":3499},"fwci":0.0,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":{"value":0.64850455,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"18","issue":"20","first_page":"3326","last_page":"3326"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10066","display_name":"Gut microbiota and health","score":0.7172999978065491,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10066","display_name":"Gut microbiota and health","score":0.7172999978065491,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11139","display_name":"Gout, Hyperuricemia, Uric Acid","score":0.2809999883174896,"subfield":{"id":"https://openalex.org/subfields/2727","display_name":"Nephrology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12964","display_name":"Diet, Metabolism, and Disease","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/hyperuricemia","display_name":"hyperuricemia","score":0.9819999933242798},{"id":"https://openalex.org/keywords/gout","display_name":"gout","score":0.996999979019165},{"id":"https://openalex.org/keywords/gut-microbiota","display_name":"gut microbiota","score":0.9950000047683716},{"id":"https://openalex.org/keywords/short-chain-fatty-acids","display_name":"short-chain fatty acids","score":0.9679999947547913},{"id":"https://openalex.org/keywords/dietary-purine-intake","display_name":"dietary purine intake","score":0.9700000286102295},{"id":"https://openalex.org/keywords/akkermansia","display_name":"Akkermansia","score":0.9539999961853027},{"id":"https://openalex.org/keywords/prevotella","display_name":"Prevotella","score":1.0},{"id":"https://openalex.org/keywords/uric-acid-metabolism","display_name":"uric acid metabolism","score":0.7319999933242798},{"id":"https://openalex.org/keywords/inflammation","display_name":"inflammation","score":0.4490000009536743}],"concepts":[{"id":"https://openalex.org/C2779721657","wikidata":"https://www.wikidata.org/wiki/Q49970","display_name":"Hyperuricemia","level":3,"score":0.6764000058174133},{"id":"https://openalex.org/C539455810","wikidata":"https://www.wikidata.org/wiki/Q739734","display_name":"Gut flora","level":2,"score":0.6625000238418579},{"id":"https://openalex.org/C61716771","wikidata":"https://www.wikidata.org/wiki/Q496","display_name":"Feces","level":2,"score":0.6535000205039978},{"id":"https://openalex.org/C2780402116","wikidata":"https://www.wikidata.org/wiki/Q133087","display_name":"Gout","level":2,"score":0.5335999727249146},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.522599995136261},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.5038999915122986},{"id":"https://openalex.org/C2776109033","wikidata":"https://www.wikidata.org/wiki/Q3884023","display_name":"Akkermansia","level":4,"score":0.47099998593330383},{"id":"https://openalex.org/C2780423288","wikidata":"https://www.wikidata.org/wiki/Q7242440","display_name":"Prevotella","level":3,"score":0.4625999927520752},{"id":"https://openalex.org/C42407357","wikidata":"https://www.wikidata.org/wiki/Q521","display_name":"Physiology","level":1,"score":0.45719999074935913},{"id":"https://openalex.org/C2779881121","wikidata":"https://www.wikidata.org/wiki/Q105522","display_name":"Uric acid","level":2,"score":0.38019999861717224},{"id":"https://openalex.org/C2779704485","wikidata":"https://www.wikidata.org/wiki/Q3825240","display_name":"Lachnospiraceae","level":5,"score":0.36890000104904175},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.3617999851703644},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.3314000070095062},{"id":"https://openalex.org/C2777910003","wikidata":"https://www.wikidata.org/wiki/Q1707292","display_name":"Asymptomatic","level":2,"score":0.32910001277923584},{"id":"https://openalex.org/C2776476023","wikidata":"https://www.wikidata.org/wiki/Q188261","display_name":"Purine","level":3,"score":0.32589998841285706},{"id":"https://openalex.org/C2776229602","wikidata":"https://www.wikidata.org/wiki/Q2698455","display_name":"Short-chain fatty acid","level":4,"score":0.32019999623298645},{"id":"https://openalex.org/C2780578515","wikidata":"https://www.wikidata.org/wiki/Q657193","display_name":"Metabolic syndrome","level":3,"score":0.3188999891281128},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.3028999865055084},{"id":"https://openalex.org/C2776706654","wikidata":"https://www.wikidata.org/wiki/Q3941444","display_name":"Roseburia","level":4,"score":0.28850001096725464},{"id":"https://openalex.org/C90924648","wikidata":"https://www.wikidata.org/wiki/Q120569","display_name":"Gastroenterology","level":1,"score":0.2815999984741211},{"id":"https://openalex.org/C2778772119","wikidata":"https://www.wikidata.org/wiki/Q6058862","display_name":"Fatty liver","level":3,"score":0.25760000944137573}],"mesh":[{"descriptor_ui":"D000069196","descriptor_name":"Gastrointestinal Microbiome","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003430","descriptor_name":"Cross-Sectional Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004032","descriptor_name":"Diet","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D005232","descriptor_name":"Fatty Acids, Volatile","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":true},{"descriptor_ui":"D005232","descriptor_name":"Fatty Acids, Volatile","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D005243","descriptor_name":"Feces","qualifier_ui":"Q000382","qualifier_name":"microbiology","is_major_topic":true},{"descriptor_ui":"D005243","descriptor_name":"Feces","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006073","descriptor_name":"Gout","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D006073","descriptor_name":"Gout","qualifier_ui":"Q000382","qualifier_name":"microbiology","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008800","descriptor_name":"Mexico","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011687","descriptor_name":"Purines","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":true},{"descriptor_ui":"D018720","descriptor_name":"Prevotella","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D033461","descriptor_name":"Hyperuricemia","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D033461","descriptor_name":"Hyperuricemia","qualifier_ui":"Q000382","qualifier_name":"microbiology","is_major_topic":true}],"locations_count":3,"locations":[{"id":"doi:10.3390/nu18203326","doi":"https://doi.org/10.3390/nu18203326","is_oa":true,"landing_page_url":"https://doi.org/10.3390/nu18203326","pdf_url":null,"source":{"id":"https://openalex.org/S110785341","display_name":"Nutrients","issn_l":"2072-6643","issn":["2072-6643"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nutrients","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:13708603","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC13708603/","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC13708603/pdf/nutrients-18-03326.pdf","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nutrients","raw_type":"Text"},{"id":"pmid:42942896","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/42942896","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nutrients","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.3390/nu18203326","doi":"https://doi.org/10.3390/nu18203326","is_oa":true,"landing_page_url":"https://doi.org/10.3390/nu18203326","pdf_url":null,"source":{"id":"https://openalex.org/S110785341","display_name":"Nutrients","issn_l":"2072-6643","issn":["2072-6643"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nutrients","raw_type":"journal-article"},"sustainable_development_goals":[{"score":1.0,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[],"funders":[{"id":"https://openalex.org/F4320332167","display_name":"Directorate for Biological Sciences","ror":"https://ror.org/001xhss06"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W7221548741.pdf","grobid_xml":"https://content.openalex.org/works/W7221548741.grobid-xml"},"referenced_works_count":34,"referenced_works":["https://openalex.org/W1599893459","https://openalex.org/W1618714494","https://openalex.org/W1948266836","https://openalex.org/W1983377204","https://openalex.org/W1984486655","https://openalex.org/W2031118520","https://openalex.org/W2078455937","https://openalex.org/W2119742837","https://openalex.org/W2133287974","https://openalex.org/W2165067288","https://openalex.org/W2166562121","https://openalex.org/W2175465469","https://openalex.org/W2236332835","https://openalex.org/W2335302945","https://openalex.org/W2409656339","https://openalex.org/W2589364187","https://openalex.org/W2808457437","https://openalex.org/W2808513510","https://openalex.org/W2809439583","https://openalex.org/W2914997630","https://openalex.org/W2978939437","https://openalex.org/W2981841221","https://openalex.org/W3164844417","https://openalex.org/W3177721978","https://openalex.org/W3188678456","https://openalex.org/W4223471954","https://openalex.org/W4239736175","https://openalex.org/W4302283522","https://openalex.org/W4381137496","https://openalex.org/W4401977857","https://openalex.org/W4408727962","https://openalex.org/W4412044124","https://openalex.org/W4412529144","https://openalex.org/W4413972137"],"related_works":["https://openalex.org/W4302283522","https://openalex.org/W7133754894","https://openalex.org/W4413255244","https://openalex.org/W4362706747","https://openalex.org/W4213391215","https://openalex.org/W7171201842","https://openalex.org/W4224929304","https://openalex.org/W4408727962","https://openalex.org/W4379522701","https://openalex.org/W3202328808"],"abstract_inverted_index":{"Background:":[0],"Hyperuricemia":[1],"and":[2,25,43,49,53,84,97,111,133,154,188,214],"gout":[3,29,87,160,189,220],"are":[4,265],"closely":[5],"associated":[6],"with":[7,39,77,86,177,197,241,262],"alterations":[8],"in":[9,159,180,218],"gut":[10,244],"microbiota":[11],"function.":[12],"Short-chain":[13],"fatty":[14],"acids":[15],"(SCFAs)":[16],"produced":[17],"by":[18,95,100,106,113,120],"intestinal":[19],"microorganisms":[20],"may":[21],"modulate":[22],"immune":[23],"responses":[24],"inflammation":[26],"relevant":[27],"to":[28,137,247,253,267],"pathophysiology.":[30],"This":[31,64],"study":[32,66],"evaluated":[33,119],"fecal":[34,54,178,215,233],"SCFA":[35,55,234],"concentrations,":[36],"their":[37],"associations":[38,176],"dietary":[40,143,248],"purine":[41,114,144,249],"intake,":[42],"the":[44,58,121,219,254],"relationship":[45],"between":[46,210],"Akkermansia":[47],"spp.":[48,51,212],"Prevotella":[50,211],"abundance":[52,99,213],"profiles":[56,235],"across":[57,236],"clinical":[59,147],"spectrum":[60],"of":[61,238,257],"hyperuricemia.":[62],"Methods:":[63],"cross-sectional":[65],"included":[67],"380":[68],"Mexican":[69],"adults:":[70],"normouricemic":[71],"controls":[72,181],"(n":[73,88],"=":[74,82,89,183,186,192,195,202,223,226],"141),":[75],"individuals":[76,166],"asymptomatic":[78],"hyperuricemia":[79],"(AH;":[80],"n":[81],"98),":[83],"patients":[85,161,190],"141).":[90],"Fecal":[91,152],"SCFAs":[92],"were":[93,118,156],"quantified":[94],"GC-FID":[96],"bacterial":[98],"qPCR.":[101],"Dietary":[102],"intake":[103,145,173,250],"was":[104,135],"assessed":[105],"semi-quantitative":[107],"food":[108,172],"frequency":[109],"questionnaire":[110],"classified":[112],"content.":[115],"Between-group":[116],"differences":[117],"Kruskal\u2013Wallis":[122],"test":[123],"(Benjamini\u2013Hochberg":[124],"correction);":[125],"multivariable":[126],"linear":[127],"regression":[128],"adjusted":[129],"for":[130],"age,":[131],"sex,":[132],"BMI":[134],"used":[136],"assess":[138],"associations,":[139],"including":[140],"a":[141,198,207,242],"pre-specified":[142],"per":[146],"group":[148,221],"interaction":[149,200],"term.":[150],"Results:":[151],"acetate":[153,179,216],"propionate":[155],"significantly":[157,168],"higher":[158,169],"than":[162],"controls,":[163],"whereas":[164],"AH":[165],"had":[167],"butyrate.":[170],"Moderate-purine":[171],"showed":[174],"opposing":[175],"(\u03b2":[182,191,222],"+3.61,":[184],"p":[185,194,225],"0.019)":[187],"\u22124.59,":[193],"0.036),":[196],"significant":[199],"(p":[201],"0.004).":[203],"Exploratory":[204],"analyses":[205],"revealed":[206],"positive":[208],"association":[209],"exclusively":[217],"0.085,":[224],"0.020).":[227],"Conclusion:":[228],"These":[229],"findings":[230],"suggest":[231],"distinct":[232],"stages":[237],"urate-related":[239],"disease,":[240],"disease-specific":[243],"metabolic":[245],"response":[246],"potentially":[251],"contributing":[252],"inflammatory":[255],"environment":[256],"established":[258],"gout.":[259],"Longitudinal":[260],"studies":[261],"whole-microbiome":[263],"profiling":[264],"needed":[266],"establish":[268],"causality.":[269]},"counts_by_year":[],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2026-10-13T00:00:00"}