{"id":"https://openalex.org/W7221508025","doi":"https://doi.org/10.4244/eij-d-26-00602","title":"Coronary artery disease management in patients with severe aortic stenosis undergoing transcatheter aortic valve implantation: a systematic review and meta-analysis of randomised controlled trials","display_name":"Coronary artery disease management in patients with severe aortic stenosis undergoing transcatheter aortic valve implantation: a systematic review and meta-analysis of randomised controlled trials","publication_year":2026,"publication_date":"2026-10-01","ids":{"openalex":"https://openalex.org/W7221508025","doi":"https://doi.org/10.4244/eij-d-26-00602","pmid":"https://pubmed.ncbi.nlm.nih.gov/42910974","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/13717718"},"language":"en","primary_location":{"id":"doi:10.4244/eij-d-26-00602","doi":"https://doi.org/10.4244/eij-d-26-00602","is_oa":false,"landing_page_url":"https://doi.org/10.4244/eij-d-26-00602","pdf_url":null,"source":{"id":"https://openalex.org/S104576203","display_name":"EuroIntervention","issn_l":"1774-024X","issn":["1774-024X","1969-6213"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4323238086","host_organization_name":"European Association of Percutaneous Cardiovascular Interventions","host_organization_lineage":["https://openalex.org/P4323238086"],"host_organization_lineage_names":["European Association of Percutaneous Cardiovascular Interventions"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"EuroIntervention","raw_type":"journal-article"},"volume":null,"type":"review","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC13717718/","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5086000459","display_name":"Kamil Bujak","orcid":"https://orcid.org/0000-0002-1951-1981","observed_orcids":["https://orcid.org/0000-0002-1951-1981"]},"institutions":[{"id":"https://openalex.org/I166182418","display_name":"Medical University of Silesia","ror":"https://ror.org/005k7hp45","country_code":"PL","type":"education","lineage":["https://openalex.org/I166182418"]},{"id":"https://openalex.org/I39063666","display_name":"University of Catania","ror":"https://ror.org/03a64bh57","country_code":"IT","type":"education","lineage":["https://openalex.org/I39063666"]},{"id":"https://openalex.org/I4210129599","display_name":"Policlinico Universitario di Catania","ror":"https://ror.org/033xwx807","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210129599"]},{"id":"https://openalex.org/I4210133622","display_name":"Silesian Center for Heart Disease","ror":"https://ror.org/04kn0zf27","country_code":"PL","type":"nonprofit","lineage":["https://openalex.org/I4210133622"]},{"id":"https://openalex.org/I4210160210","display_name":"Azienda Ospedaliero Universitaria Policlinico \"G.Rodolico - San Marco\"","ror":"https://ror.org/051tt6c85","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210160210"]}],"countries":["IT","PL"],"is_corresponding":false,"raw_author_name":"Kamil Bujak","raw_affiliation_strings":["3rd Department of Cardiology, Silesian Center for Heart Diseases, Zabrze, Poland and Faculty of Medical Sciences, Medical University of Silesia, Katowice, Poland","Department of Pharmacology, Faculty of Medical Sciences in Zabrze, Medical University of Silesia, Katowice, Poland","Division of Cardiology, Azienda Ospedaliero-Universitaria Policlinico \"G. Rodolico-San Marco\", University of Catania, Catania, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"3rd Department of Cardiology, Silesian Center for Heart Diseases, Zabrze, Poland and Faculty of Medical Sciences, Medical University of Silesia, Katowice, Poland","institution_ids":["https://openalex.org/I166182418","https://openalex.org/I4210133622"]},{"raw_affiliation_string":"Department of Pharmacology, Faculty of Medical Sciences in Zabrze, Medical University of Silesia, Katowice, Poland","institution_ids":["https://openalex.org/I166182418"]},{"raw_affiliation_string":"Division of Cardiology, Azienda Ospedaliero-Universitaria Policlinico \"G. Rodolico-San Marco\", University of Catania, Catania, Italy","institution_ids":["https://openalex.org/I39063666","https://openalex.org/I4210129599","https://openalex.org/I4210160210"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5068482307","display_name":"Daniele Giacoppo","orcid":"https://orcid.org/0000-0001-9008-3011","observed_orcids":["https://orcid.org/0000-0001-9008-3011"]},"institutions":[{"id":"https://openalex.org/I39063666","display_name":"University of Catania","ror":"https://ror.org/03a64bh57","country_code":"IT","type":"education","lineage":["https://openalex.org/I39063666"]},{"id":"https://openalex.org/I4210129599","display_name":"Policlinico Universitario di Catania","ror":"https://ror.org/033xwx807","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210129599"]},{"id":"https://openalex.org/I4210160210","display_name":"Azienda Ospedaliero Universitaria Policlinico \"G.Rodolico - San Marco\"","ror":"https://ror.org/051tt6c85","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210160210"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Daniele Giacoppo","raw_affiliation_strings":["Division of Cardiology, Azienda Ospedaliero-Universitaria Policlinico \"G. Rodolico-San Marco\", University of Catania, Catania, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Cardiology, Azienda Ospedaliero-Universitaria Policlinico \"G. Rodolico-San Marco\", University of Catania, Catania, Italy","institution_ids":["https://openalex.org/I39063666","https://openalex.org/I4210129599","https://openalex.org/I4210160210"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5029354324","display_name":"Claudio Laudani","orcid":"https://orcid.org/0000-0001-5467-7402","observed_orcids":["https://orcid.org/0000-0001-5467-7402"]},"institutions":[{"id":"https://openalex.org/I39063666","display_name":"University of Catania","ror":"https://ror.org/03a64bh57","country_code":"IT","type":"education","lineage":["https://openalex.org/I39063666"]},{"id":"https://openalex.org/I4210129599","display_name":"Policlinico Universitario di Catania","ror":"https://ror.org/033xwx807","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210129599"]},{"id":"https://openalex.org/I4210160210","display_name":"Azienda Ospedaliero Universitaria Policlinico \"G.Rodolico - San Marco\"","ror":"https://ror.org/051tt6c85","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210160210"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Claudio Laudani","raw_affiliation_strings":["Division of Cardiology, Azienda Ospedaliero-Universitaria Policlinico \"G. Rodolico-San Marco\", University of Catania, Catania, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Cardiology, Azienda Ospedaliero-Universitaria Policlinico \"G. Rodolico-San Marco\", University of Catania, Catania, Italy","institution_ids":["https://openalex.org/I39063666","https://openalex.org/I4210129599","https://openalex.org/I4210160210"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5034270893","display_name":"Marco Spagnolo","orcid":"https://orcid.org/0000-0002-5434-607X","observed_orcids":["https://orcid.org/0000-0002-5434-607X"]},"institutions":[{"id":"https://openalex.org/I39063666","display_name":"University of Catania","ror":"https://ror.org/03a64bh57","country_code":"IT","type":"education","lineage":["https://openalex.org/I39063666"]},{"id":"https://openalex.org/I4210129599","display_name":"Policlinico Universitario di Catania","ror":"https://ror.org/033xwx807","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210129599"]},{"id":"https://openalex.org/I4210160210","display_name":"Azienda Ospedaliero Universitaria Policlinico \"G.Rodolico - San Marco\"","ror":"https://ror.org/051tt6c85","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210160210"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Marco Spagnolo","raw_affiliation_strings":["Division of Cardiology, Azienda Ospedaliero-Universitaria Policlinico \"G. Rodolico-San Marco\", University of Catania, Catania, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Cardiology, Azienda Ospedaliero-Universitaria Policlinico \"G. Rodolico-San Marco\", University of Catania, Catania, Italy","institution_ids":["https://openalex.org/I39063666","https://openalex.org/I4210129599","https://openalex.org/I4210160210"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5066106914","display_name":"Placido Maria Mazzone","orcid":"https://orcid.org/0000-0002-0621-4224","observed_orcids":["https://orcid.org/0000-0002-0621-4224"]},"institutions":[{"id":"https://openalex.org/I39063666","display_name":"University of Catania","ror":"https://ror.org/03a64bh57","country_code":"IT","type":"education","lineage":["https://openalex.org/I39063666"]},{"id":"https://openalex.org/I4210129599","display_name":"Policlinico Universitario di Catania","ror":"https://ror.org/033xwx807","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210129599"]},{"id":"https://openalex.org/I4210160210","display_name":"Azienda Ospedaliero Universitaria Policlinico \"G.Rodolico - San Marco\"","ror":"https://ror.org/051tt6c85","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210160210"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Placido Maria Mazzone","raw_affiliation_strings":["Division of Cardiology, Azienda Ospedaliero-Universitaria Policlinico \"G. Rodolico-San Marco\", University of Catania, Catania, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Cardiology, Azienda Ospedaliero-Universitaria Policlinico \"G. Rodolico-San Marco\", University of Catania, Catania, Italy","institution_ids":["https://openalex.org/I39063666","https://openalex.org/I4210129599","https://openalex.org/I4210160210"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5047328430","display_name":"Maria Sara Mauro","orcid":"https://orcid.org/0000-0001-9432-9314","observed_orcids":["https://orcid.org/0000-0001-9432-9314"]},"institutions":[{"id":"https://openalex.org/I39063666","display_name":"University of Catania","ror":"https://ror.org/03a64bh57","country_code":"IT","type":"education","lineage":["https://openalex.org/I39063666"]},{"id":"https://openalex.org/I4210129599","display_name":"Policlinico Universitario di Catania","ror":"https://ror.org/033xwx807","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210129599"]},{"id":"https://openalex.org/I4210160210","display_name":"Azienda Ospedaliero Universitaria Policlinico \"G.Rodolico - San Marco\"","ror":"https://ror.org/051tt6c85","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210160210"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Maria Sara Mauro","raw_affiliation_strings":["Division of Cardiology, Azienda Ospedaliero-Universitaria Policlinico \"G. Rodolico-San Marco\", University of Catania, Catania, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Cardiology, Azienda Ospedaliero-Universitaria Policlinico \"G. Rodolico-San Marco\", University of Catania, Catania, Italy","institution_ids":["https://openalex.org/I39063666","https://openalex.org/I4210129599","https://openalex.org/I4210160210"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5092113454","display_name":"Luigi Cutore","orcid":"https://orcid.org/0009-0006-3536-8341","observed_orcids":["https://orcid.org/0009-0006-3536-8341"]},"institutions":[{"id":"https://openalex.org/I39063666","display_name":"University of Catania","ror":"https://ror.org/03a64bh57","country_code":"IT","type":"education","lineage":["https://openalex.org/I39063666"]},{"id":"https://openalex.org/I4210129599","display_name":"Policlinico Universitario di Catania","ror":"https://ror.org/033xwx807","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210129599"]},{"id":"https://openalex.org/I4210160210","display_name":"Azienda Ospedaliero Universitaria Policlinico \"G.Rodolico - San Marco\"","ror":"https://ror.org/051tt6c85","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210160210"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Luigi Cutore","raw_affiliation_strings":["Division of Cardiology, Azienda Ospedaliero-Universitaria Policlinico \"G. Rodolico-San Marco\", University of Catania, Catania, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Cardiology, Azienda Ospedaliero-Universitaria Policlinico \"G. Rodolico-San Marco\", University of Catania, Catania, Italy","institution_ids":["https://openalex.org/I39063666","https://openalex.org/I4210129599","https://openalex.org/I4210160210"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5122256682","display_name":"Giacinto Di Leo","orcid":"https://orcid.org/0009-0001-3583-3331","observed_orcids":["https://orcid.org/0009-0001-3583-3331"]},"institutions":[{"id":"https://openalex.org/I39063666","display_name":"University of Catania","ror":"https://ror.org/03a64bh57","country_code":"IT","type":"education","lineage":["https://openalex.org/I39063666"]},{"id":"https://openalex.org/I4210129599","display_name":"Policlinico Universitario di Catania","ror":"https://ror.org/033xwx807","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210129599"]},{"id":"https://openalex.org/I4210160210","display_name":"Azienda Ospedaliero Universitaria Policlinico \"G.Rodolico - San Marco\"","ror":"https://ror.org/051tt6c85","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210160210"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Giacinto Di Leo","raw_affiliation_strings":["Division of Cardiology, Azienda Ospedaliero-Universitaria Policlinico \"G. Rodolico-San Marco\", University of Catania, Catania, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Cardiology, Azienda Ospedaliero-Universitaria Policlinico \"G. Rodolico-San Marco\", University of Catania, Catania, Italy","institution_ids":["https://openalex.org/I39063666","https://openalex.org/I4210129599","https://openalex.org/I4210160210"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5078233605","display_name":"Simone Finocchiaro","orcid":"https://orcid.org/0000-0002-3974-3878","observed_orcids":["https://orcid.org/0000-0002-3974-3878"]},"institutions":[{"id":"https://openalex.org/I39063666","display_name":"University of Catania","ror":"https://ror.org/03a64bh57","country_code":"IT","type":"education","lineage":["https://openalex.org/I39063666"]},{"id":"https://openalex.org/I4210129599","display_name":"Policlinico Universitario di Catania","ror":"https://ror.org/033xwx807","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210129599"]},{"id":"https://openalex.org/I4210160210","display_name":"Azienda Ospedaliero Universitaria Policlinico \"G.Rodolico - San Marco\"","ror":"https://ror.org/051tt6c85","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210160210"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Simone Finocchiaro","raw_affiliation_strings":["Division of Cardiology, Azienda Ospedaliero-Universitaria Policlinico \"G. Rodolico-San Marco\", University of Catania, Catania, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Cardiology, Azienda Ospedaliero-Universitaria Policlinico \"G. Rodolico-San Marco\", University of Catania, Catania, Italy","institution_ids":["https://openalex.org/I39063666","https://openalex.org/I4210129599","https://openalex.org/I4210160210"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5048882118","display_name":"Antonio Greco","orcid":"https://orcid.org/0000-0003-2926-9428","observed_orcids":["https://orcid.org/0000-0003-2926-9428"]},"institutions":[{"id":"https://openalex.org/I39063666","display_name":"University of Catania","ror":"https://ror.org/03a64bh57","country_code":"IT","type":"education","lineage":["https://openalex.org/I39063666"]},{"id":"https://openalex.org/I4210129599","display_name":"Policlinico Universitario di Catania","ror":"https://ror.org/033xwx807","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210129599"]},{"id":"https://openalex.org/I4210160210","display_name":"Azienda Ospedaliero Universitaria Policlinico \"G.Rodolico - San Marco\"","ror":"https://ror.org/051tt6c85","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210160210"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Antonio Greco","raw_affiliation_strings":["Division of Cardiology, Azienda Ospedaliero-Universitaria Policlinico \"G. Rodolico-San Marco\", University of Catania, Catania, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Cardiology, Azienda Ospedaliero-Universitaria Policlinico \"G. Rodolico-San Marco\", University of Catania, Catania, Italy","institution_ids":["https://openalex.org/I39063666","https://openalex.org/I4210129599","https://openalex.org/I4210160210"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5087550320","display_name":"Davide Capodanno","orcid":"https://orcid.org/0000-0002-5156-7723","observed_orcids":["https://orcid.org/0000-0002-5156-7723"]},"institutions":[{"id":"https://openalex.org/I39063666","display_name":"University of Catania","ror":"https://ror.org/03a64bh57","country_code":"IT","type":"education","lineage":["https://openalex.org/I39063666"]},{"id":"https://openalex.org/I4210129599","display_name":"Policlinico Universitario di Catania","ror":"https://ror.org/033xwx807","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210129599"]},{"id":"https://openalex.org/I4210160210","display_name":"Azienda Ospedaliero Universitaria Policlinico \"G.Rodolico - San Marco\"","ror":"https://ror.org/051tt6c85","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210160210"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Davide Capodanno","raw_affiliation_strings":["Division of Cardiology, Azienda Ospedaliero-Universitaria Policlinico \"G. Rodolico-San Marco\", University of Catania, Catania, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Cardiology, Azienda Ospedaliero-Universitaria Policlinico \"G. Rodolico-San Marco\", University of Catania, Catania, Italy","institution_ids":["https://openalex.org/I39063666","https://openalex.org/I4210129599","https://openalex.org/I4210160210"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":5,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":1.1605,"has_fulltext":false,"cited_by_count":1,"citation_normalized_percentile":{"value":0.84139422,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":92,"max":95},"biblio":{"volume":"22","issue":"20","first_page":"e1082","last_page":"e1091"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10172","display_name":"Cardiac Valve Diseases and Treatments","score":0.9970999956130981,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10172","display_name":"Cardiac Valve Diseases and Treatments","score":0.9970999956130981,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10193","display_name":"Coronary Interventions and Diagnostics","score":0.00139999995008111,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10372","display_name":"Cardiac Imaging and Diagnostics","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/coronary-artery-disease","display_name":"coronary artery disease","score":0.9620000123977661},{"id":"https://openalex.org/keywords/severe-aortic-stenosis","display_name":"severe aortic stenosis","score":0.949999988079071},{"id":"https://openalex.org/keywords/transcatheter-aortic-valve-replacement","display_name":"transcatheter aortic valve implantation","score":0.9990000128746033},{"id":"https://openalex.org/keywords/percutaneous-coronary-intervention","display_name":"percutaneous coronary intervention","score":0.7400000095367432},{"id":"https://openalex.org/keywords/coronary-stenting","display_name":"coronary stenting","score":0.39899998903274536},{"id":"https://openalex.org/keywords/tavi-outcomes","display_name":"TAVI outcomes","score":0.3779999911785126}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9916999936103821},{"id":"https://openalex.org/C164705383","wikidata":"https://www.wikidata.org/wiki/Q10379","display_name":"Cardiology","level":1,"score":0.746999979019165},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.7059999704360962},{"id":"https://openalex.org/C2780007028","wikidata":"https://www.wikidata.org/wiki/Q2343082","display_name":"Stenosis","level":2,"score":0.6481000185012817},{"id":"https://openalex.org/C2778213512","wikidata":"https://www.wikidata.org/wiki/Q844935","display_name":"Coronary artery disease","level":2,"score":0.5414999723434448},{"id":"https://openalex.org/C168563851","wikidata":"https://www.wikidata.org/wiki/Q1436668","display_name":"Randomized controlled trial","level":2,"score":0.42640000581741333},{"id":"https://openalex.org/C2781414266","wikidata":"https://www.wikidata.org/wiki/Q531019","display_name":"Aortic valve stenosis","level":3,"score":0.4205999970436096},{"id":"https://openalex.org/C2982889124","wikidata":"https://www.wikidata.org/wiki/Q107439039","display_name":"Disease management","level":4,"score":0.367000013589859},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.3517000079154968},{"id":"https://openalex.org/C2779473830","wikidata":"https://www.wikidata.org/wiki/Q1540899","display_name":"MEDLINE","level":2,"score":0.3384999930858612},{"id":"https://openalex.org/C2780714102","wikidata":"https://www.wikidata.org/wiki/Q616071","display_name":"Aortic valve","level":2,"score":0.33809998631477356},{"id":"https://openalex.org/C2780026749","wikidata":"https://www.wikidata.org/wiki/Q7912830","display_name":"Valve replacement","level":3,"score":0.32839998602867126},{"id":"https://openalex.org/C535046627","wikidata":"https://www.wikidata.org/wiki/Q30612","display_name":"Clinical trial","level":2,"score":0.326200008392334},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.3206000030040741},{"id":"https://openalex.org/C2776820930","wikidata":"https://www.wikidata.org/wiki/Q9655","display_name":"Artery","level":2,"score":0.304500013589859},{"id":"https://openalex.org/C2777466421","wikidata":"https://www.wikidata.org/wiki/Q1266890","display_name":"Vascular disease","level":2,"score":0.28679999709129333},{"id":"https://openalex.org/C2777385415","wikidata":"https://www.wikidata.org/wiki/Q1615191","display_name":"Cardiac catheterization","level":2,"score":0.2849999964237213},{"id":"https://openalex.org/C2779736815","wikidata":"https://www.wikidata.org/wiki/Q1130519","display_name":"valvular heart disease","level":2,"score":0.27090001106262207},{"id":"https://openalex.org/C30036603","wikidata":"https://www.wikidata.org/wiki/Q17125150","display_name":"Severity of illness","level":2,"score":0.2619999945163727},{"id":"https://openalex.org/C2781274984","wikidata":"https://www.wikidata.org/wiki/Q3559674","display_name":"Interventional cardiology","level":2,"score":0.25920000672340393}],"mesh":[{"descriptor_ui":"D001024","descriptor_name":"Aortic Valve Stenosis","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":true},{"descriptor_ui":"D001024","descriptor_name":"Aortic Valve Stenosis","qualifier_ui":"Q000601","qualifier_name":"surgery","is_major_topic":true},{"descriptor_ui":"D003324","descriptor_name":"Coronary Artery Disease","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":true},{"descriptor_ui":"D003324","descriptor_name":"Coronary Artery Disease","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012720","descriptor_name":"Severity of Illness Index","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016032","descriptor_name":"Randomized Controlled Trials as Topic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016896","descriptor_name":"Treatment Outcome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D062645","descriptor_name":"Percutaneous Coronary Intervention","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D065467","descriptor_name":"Transcatheter Aortic Valve Replacement","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true}],"locations_count":3,"locations":[{"id":"doi:10.4244/eij-d-26-00602","doi":"https://doi.org/10.4244/eij-d-26-00602","is_oa":false,"landing_page_url":"https://doi.org/10.4244/eij-d-26-00602","pdf_url":null,"source":{"id":"https://openalex.org/S104576203","display_name":"EuroIntervention","issn_l":"1774-024X","issn":["1774-024X","1969-6213"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4323238086","host_organization_name":"European Association of Percutaneous Cardiovascular Interventions","host_organization_lineage":["https://openalex.org/P4323238086"],"host_organization_lineage_names":["European Association of Percutaneous Cardiovascular Interventions"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"EuroIntervention","raw_type":"journal-article"},{"id":"pmid:42910974","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/42910974","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:13717718","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC13717718/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"EuroIntervention","raw_type":"Text"}],"best_oa_location":{"id":"pmh:oai:pubmedcentral.nih.gov:13717718","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC13717718/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"EuroIntervention","raw_type":"Text"},"sustainable_development_goals":[{"score":1.0,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Systematic Review","id":"https://openalex.org/study-designs/systematic-review"},{"display_name":"Meta-Analysis","id":"https://openalex.org/study-designs/meta-analysis"}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":36,"referenced_works":["https://openalex.org/W173091792","https://openalex.org/W1484080302","https://openalex.org/W1617328014","https://openalex.org/W2016785465","https://openalex.org/W2149609916","https://openalex.org/W2160414137","https://openalex.org/W2726155843","https://openalex.org/W2808359328","https://openalex.org/W2898696166","https://openalex.org/W2917964765","https://openalex.org/W2967765261","https://openalex.org/W2970684805","https://openalex.org/W2976969014","https://openalex.org/W3014025744","https://openalex.org/W3110765623","https://openalex.org/W3199019011","https://openalex.org/W4321612395","https://openalex.org/W4365484936","https://openalex.org/W4383998540","https://openalex.org/W4384831257","https://openalex.org/W4386590116","https://openalex.org/W4396675991","https://openalex.org/W4397033869","https://openalex.org/W4401035990","https://openalex.org/W4402064302","https://openalex.org/W4402080669","https://openalex.org/W4403191060","https://openalex.org/W4405010470","https://openalex.org/W4405198202","https://openalex.org/W4409147648","https://openalex.org/W4413812708","https://openalex.org/W4417134726","https://openalex.org/W4417164420","https://openalex.org/W4417516747","https://openalex.org/W7142642663","https://openalex.org/W7162437202"],"related_works":["https://openalex.org/W4306254753","https://openalex.org/W4306255182","https://openalex.org/W2415384713","https://openalex.org/W4318755537","https://openalex.org/W4401425505","https://openalex.org/W7160029985","https://openalex.org/W3163519447","https://openalex.org/W4402080669","https://openalex.org/W7161819876","https://openalex.org/W2094265494"],"abstract_inverted_index":{"BACKGROUND:":[0],"The":[1,87],"optimal":[2],"management":[3,35],"of":[4,46,54,79,95,107,152,175,221],"coronary":[5,31,65],"artery":[6],"disease":[7],"in":[8,36,127,135],"patients":[9,37,212],"with":[10,68,142,149,197,225,236],"severe":[11],"aortic":[12,16],"stenosis":[13],"undergoing":[14,38],"transcatheter":[15],"valve":[17],"implantation":[18],"(TAVI)":[19],"remains":[20],"uncertain.":[21],"AIMS:":[22],"We":[23,58],"aimed":[24],"to":[25,41],"compare":[26],"clinical":[27],"outcomes":[28,106,206,223],"between":[29],"routine":[30,145,216],"revascularisation":[32,48,165,195,208,217],"and":[33,40,71,84,117,131,163,171,193,200],"conservative":[34,69,143,198,226],"TAVI":[39],"assess":[42],"the":[43,76,104,128,136,184,219,237],"relative":[44,77],"effectiveness":[45,78],"individual":[47,80,105],"strategies":[49],"by":[50],"performing":[51],"a":[52,60,72,91],"meta-analysis":[53,62,74],"randomised":[55],"trials.":[56],"METHODS:":[57],"conducted":[59],"pairwise":[61],"comparing":[63,75],"percutaneous":[64],"intervention":[66],"(PCI)":[67],"treatment":[70,199],"network":[73,185],"strategies,":[81],"including":[82],"angiography-guided":[83],"physiology-guided":[85,187,231],"PCI.":[86],"primary":[88,137],"outcome":[89],"was":[90,147],"study-defined":[92],"composite":[93],"endpoint":[94],"major":[96,118,176],"adverse":[97],"cardiovascular":[98,110],"events":[99],"(MACE).":[100],"Secondary":[101],"endpoints":[102],"included":[103,126,134],"all-cause":[108],"death,":[109,111],"myocardial":[112],"infarction,":[113],"stroke,":[114,192],"unplanned":[115,164,194],"revascularisation,":[116],"bleeding.":[119],"RESULTS:":[120],"Five":[121],"trials":[122],"(N=1,644":[123],"patients)":[124],"were":[125,133],"systematic":[129],"review,":[130],"four":[132],"quantitative":[138],"synthesis":[139],"(N=1,476).":[140],"Compared":[141],"treatment,":[144],"PCI":[146,188,232],"associated":[148,235],"lower":[150],"risks":[151],"MACE":[153],"(risk":[154],"ratio":[155],"[RR]":[156],"0.80,":[157],"95%":[158,168,180],"confidence":[159],"interval":[160],"[CI]:":[161],"0.65-0.98)":[162],"(RR":[166,178],"0.30,":[167],"CI:":[169,181],"0.11-0.83)":[170],"an":[172],"increased":[173],"risk":[174,220],"bleeding":[177],"1.57,":[179],"1.07-2.32).":[182],"In":[183,228],"meta-analysis,":[186],"significantly":[189],"reduced":[190],"MACE,":[191],"compared":[196,224],"ranked":[201],"highest":[202],"for":[203,214],"all":[204],"ischaemic":[205,222],"among":[207],"strategies.":[209,244],"CONCLUSIONS:":[210],"Among":[211],"referred":[213],"TAVI,":[215],"reduces":[218],"treatment.":[227],"this":[229],"setting,":[230],"may":[233],"be":[234],"most":[238],"favourable":[239],"efficacy":[240],"profile":[241],"across":[242],"available":[243],"(PROSPERO:":[245],"CRD420261330194).":[246]},"counts_by_year":[{"year":2026,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2026-10-13T00:00:00"}