{"id":"https://openalex.org/W7221480102","doi":"https://doi.org/10.64898/2026.10.08.26365096","title":"Pulsed Field Versus Radiofrequency Ablation For Repeat Ablation of Atrial Fibrillation: Evaluation of Outcomes","display_name":"Pulsed Field Versus Radiofrequency Ablation For Repeat Ablation of Atrial Fibrillation: Evaluation of Outcomes","publication_year":2026,"publication_date":"2026-10-11","ids":{"openalex":"https://openalex.org/W7221480102","doi":"https://doi.org/10.64898/2026.10.08.26365096"},"language":"en","primary_location":{"id":"doi:10.64898/2026.10.08.26365096","doi":"https://doi.org/10.64898/2026.10.08.26365096","is_oa":false,"landing_page_url":"https://doi.org/10.64898/2026.10.08.26365096","pdf_url":null,"source":{"id":"https://openalex.org/S3005729997","display_name":"medRxiv","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":["https://openalex.org/P4310315909"],"host_organization_lineage_names":["Cold Spring Harbor Laboratory Press"],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"medRxiv","raw_type":"posted-content"},"volume":null,"type":"preprint","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5102913092","display_name":"Vishal Patel","orcid":"https://orcid.org/0000-0001-8709-5011","observed_orcids":["https://orcid.org/0000-0001-8709-5011","https://orcid.org/0000-0002-1517-4148"]},"institutions":[{"id":"https://openalex.org/I51713134","display_name":"University of Colorado Anschutz","ror":"https://ror.org/03wmf1y16","country_code":"US","type":"education","lineage":["https://openalex.org/I51713134"]},{"id":"https://openalex.org/I921990950","display_name":"University of Colorado Denver","ror":"https://ror.org/02hh7en24","country_code":"US","type":"education","lineage":["https://openalex.org/I921990950"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Vishal Patel","raw_affiliation_strings":["University of Colorado School of Medicine, Aurora, CO"],"raw_orcid":"https://orcid.org/0000-0001-8709-5011","affiliations":[{"raw_affiliation_string":"University of Colorado School of Medicine, Aurora, CO","institution_ids":["https://openalex.org/I51713134","https://openalex.org/I921990950"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5048918834","display_name":"Carmel Ashur","orcid":"https://orcid.org/0000-0003-1811-5730","observed_orcids":["https://orcid.org/0000-0003-1811-5730"]},"institutions":[{"id":"https://openalex.org/I174354714","display_name":"Trinity Health Michigan","ror":"https://ror.org/01w8eym62","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1304269903","https://openalex.org/I174354714"]},{"id":"https://openalex.org/I51713134","display_name":"University of Colorado Anschutz","ror":"https://ror.org/03wmf1y16","country_code":"US","type":"education","lineage":["https://openalex.org/I51713134"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Carmel Ashur","raw_affiliation_strings":["Trinity Health Michigan Heart, Ann Arbor, MI","University of Colorado Anschutz Medical Campus, Division of Cardiology"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Trinity Health Michigan Heart, Ann Arbor, MI","institution_ids":["https://openalex.org/I174354714"]},{"raw_affiliation_string":"University of Colorado Anschutz Medical Campus, Division of Cardiology","institution_ids":["https://openalex.org/I51713134"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5065738597","display_name":"Joseph Adewumi","orcid":"https://orcid.org/0000-0002-0786-1933","observed_orcids":["https://orcid.org/0000-0002-0786-1933"]},"institutions":[{"id":"https://openalex.org/I51713134","display_name":"University of Colorado Anschutz","ror":"https://ror.org/03wmf1y16","country_code":"US","type":"education","lineage":["https://openalex.org/I51713134"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Joseph Adewumi","raw_affiliation_strings":["University of Colorado Anschutz Medical Campus, Division of Cardiology"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Colorado Anschutz Medical Campus, Division of Cardiology","institution_ids":["https://openalex.org/I51713134"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5018068593","display_name":"Kishan Padalia","orcid":"https://orcid.org/0000-0002-5894-9679","observed_orcids":["https://orcid.org/0000-0002-5894-9679"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Kishan Padalia","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-5894-9679","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5032347518","display_name":"Matthew Michael Zipse","orcid":"https://orcid.org/0000-0002-5662-8505","observed_orcids":["https://orcid.org/0000-0002-5662-8505"]},"institutions":[{"id":"https://openalex.org/I51713134","display_name":"University of Colorado Anschutz","ror":"https://ror.org/03wmf1y16","country_code":"US","type":"education","lineage":["https://openalex.org/I51713134"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Matthew M. Zipse","raw_affiliation_strings":["University of Colorado Anschutz Medical Campus, Division of Cardiology"],"raw_orcid":"https://orcid.org/0000-0002-5662-8505","affiliations":[{"raw_affiliation_string":"University of Colorado Anschutz Medical Campus, Division of Cardiology","institution_ids":["https://openalex.org/I51713134"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5158375506","display_name":"Alexis Tumolo","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I51713134","display_name":"University of Colorado Anschutz","ror":"https://ror.org/03wmf1y16","country_code":"US","type":"education","lineage":["https://openalex.org/I51713134"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Alexis Z. Tumolo","raw_affiliation_strings":["University of Colorado Anschutz Medical Campus, Division of Cardiology"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Colorado Anschutz Medical Campus, Division of Cardiology","institution_ids":["https://openalex.org/I51713134"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5058396008","display_name":"Lohit Garg","orcid":"https://orcid.org/0000-0002-9387-4369","observed_orcids":["https://orcid.org/0000-0002-9387-4369"]},"institutions":[{"id":"https://openalex.org/I51713134","display_name":"University of Colorado Anschutz","ror":"https://ror.org/03wmf1y16","country_code":"US","type":"education","lineage":["https://openalex.org/I51713134"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Lohit Garg","raw_affiliation_strings":["University of Colorado Anschutz Medical Campus, Division of Cardiology"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Colorado Anschutz Medical Campus, Division of Cardiology","institution_ids":["https://openalex.org/I51713134"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5158376623","display_name":"Rafay Sabzwari","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I51713134","display_name":"University of Colorado Anschutz","ror":"https://ror.org/03wmf1y16","country_code":"US","type":"education","lineage":["https://openalex.org/I51713134"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Syed Rafay Ali Sabzwari","raw_affiliation_strings":["University of Colorado Anschutz Medical Campus, Division of Cardiology"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Colorado Anschutz Medical Campus, Division of Cardiology","institution_ids":["https://openalex.org/I51713134"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5060915805","display_name":"Amneet Sandhu","orcid":"https://orcid.org/0000-0002-6435-5746","observed_orcids":["https://orcid.org/0000-0002-6435-5746"]},"institutions":[{"id":"https://openalex.org/I4210113540","display_name":"VA Rocky Mountain Network","ror":"https://ror.org/01x6zzb23","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1322918889","https://openalex.org/I2799886695","https://openalex.org/I4210113540"]},{"id":"https://openalex.org/I51713134","display_name":"University of Colorado Anschutz","ror":"https://ror.org/03wmf1y16","country_code":"US","type":"education","lineage":["https://openalex.org/I51713134"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Amneet Sandhu","raw_affiliation_strings":["Section of Cardiology, Rocky Mountain Regional VA Medical Center","University of Colorado Anschutz Medical Campus, Division of Cardiology"],"raw_orcid":"https://orcid.org/0000-0002-6435-5746","affiliations":[{"raw_affiliation_string":"Section of Cardiology, Rocky Mountain Regional VA Medical Center","institution_ids":["https://openalex.org/I4210113540"]},{"raw_affiliation_string":"University of Colorado Anschutz Medical Campus, Division of Cardiology","institution_ids":["https://openalex.org/I51713134"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5085940278","display_name":"Michael A. Rosenberg","orcid":"https://orcid.org/0000-0002-6708-1648","observed_orcids":["https://orcid.org/0000-0002-6708-1648"]},"institutions":[{"id":"https://openalex.org/I51713134","display_name":"University of Colorado Anschutz","ror":"https://ror.org/03wmf1y16","country_code":"US","type":"education","lineage":["https://openalex.org/I51713134"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Michael A. Rosenberg","raw_affiliation_strings":["University of Colorado Anschutz Medical Campus, Division of Cardiology"],"raw_orcid":"https://orcid.org/0000-0002-6708-1648","affiliations":[{"raw_affiliation_string":"University of Colorado Anschutz Medical Campus, Division of Cardiology","institution_ids":["https://openalex.org/I51713134"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5022135400","display_name":"Wendy S. Tzou","orcid":"https://orcid.org/0000-0002-8514-1165","observed_orcids":["https://orcid.org/0000-0002-8514-1165"]},"institutions":[{"id":"https://openalex.org/I51713134","display_name":"University of Colorado Anschutz","ror":"https://ror.org/03wmf1y16","country_code":"US","type":"education","lineage":["https://openalex.org/I51713134"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Wendy S. Tzou","raw_affiliation_strings":["University of Colorado Anschutz Medical Campus, Division of Cardiology"],"raw_orcid":"https://orcid.org/0000-0002-8514-1165","affiliations":[{"raw_affiliation_string":"University of Colorado Anschutz Medical Campus, Division of Cardiology","institution_ids":["https://openalex.org/I51713134"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10065","display_name":"Atrial Fibrillation Management and Outcomes","score":0.9955999851226807,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10065","display_name":"Atrial Fibrillation Management and Outcomes","score":0.9955999851226807,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11217","display_name":"Cardiac Arrhythmias and Treatments","score":0.00419999985024333,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10598","display_name":"Cardiac pacing and defibrillation studies","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/pulsed-field-ablation","display_name":"pulsed field ablation","score":0.9300000071525574},{"id":"https://openalex.org/keywords/radiofrequency-ablation","display_name":"radiofrequency ablation","score":0.8640000224113464},{"id":"https://openalex.org/keywords/atrial-fibrillation","display_name":"atrial fibrillation","score":0.9169999957084656},{"id":"https://openalex.org/keywords/repeat-catheter-ablation","display_name":"repeat ablation","score":0.7889999747276306},{"id":"https://openalex.org/keywords/atrial-fibrillation-recurrence","display_name":"atrial fibrillation recurrence","score":0.7400000095367432},{"id":"https://openalex.org/keywords/arrhythmia-recurrence","display_name":"arrhythmia recurrence","score":0.8700000047683716},{"id":"https://openalex.org/keywords/arrhythmia-free-survival","display_name":"arrhythmia-free survival","score":0.9070000052452087},{"id":"https://openalex.org/keywords/procedural-outcomes","display_name":"procedural outcomes","score":0.5870000123977661},{"id":"https://openalex.org/keywords/fluoroscopy-time","display_name":"fluoroscopy time","score":0.7870000004768372},{"id":"https://openalex.org/keywords/vascular-access-complications","display_name":"vascular access complications","score":0.6940000057220459}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9271000027656555},{"id":"https://openalex.org/C2777377203","wikidata":"https://www.wikidata.org/wiki/Q1809554","display_name":"Radiofrequency ablation","level":3,"score":0.8560000061988831},{"id":"https://openalex.org/C2778902805","wikidata":"https://www.wikidata.org/wiki/Q322177","display_name":"Ablation","level":2,"score":0.8309000134468079},{"id":"https://openalex.org/C2779161974","wikidata":"https://www.wikidata.org/wiki/Q815819","display_name":"Atrial fibrillation","level":2,"score":0.8230999708175659},{"id":"https://openalex.org/C2776805002","wikidata":"https://www.wikidata.org/wiki/Q614984","display_name":"Fluoroscopy","level":2,"score":0.5950000286102295},{"id":"https://openalex.org/C2776131983","wikidata":"https://www.wikidata.org/wiki/Q436572","display_name":"Catheter ablation","level":3,"score":0.5152000188827515},{"id":"https://openalex.org/C2777611987","wikidata":"https://www.wikidata.org/wiki/Q436572","display_name":"Ablation of atrial fibrillation","level":4,"score":0.41780000925064087},{"id":"https://openalex.org/C164705383","wikidata":"https://www.wikidata.org/wiki/Q10379","display_name":"Cardiology","level":1,"score":0.4108999967575073},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.37709999084472656},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.3765000104904175},{"id":"https://openalex.org/C126838900","wikidata":"https://www.wikidata.org/wiki/Q77604","display_name":"Radiology","level":1,"score":0.35929998755455017},{"id":"https://openalex.org/C72563966","wikidata":"https://www.wikidata.org/wiki/Q1303415","display_name":"Cohort","level":2,"score":0.35120001435279846},{"id":"https://openalex.org/C17923572","wikidata":"https://www.wikidata.org/wiki/Q7250160","display_name":"Propensity score matching","level":2,"score":0.3328000009059906},{"id":"https://openalex.org/C167135981","wikidata":"https://www.wikidata.org/wiki/Q2146302","display_name":"Retrospective cohort study","level":2,"score":0.3125999867916107},{"id":"https://openalex.org/C197934379","wikidata":"https://www.wikidata.org/wiki/Q2047938","display_name":"Adverse effect","level":2,"score":0.3095000088214874},{"id":"https://openalex.org/C76856502","wikidata":"https://www.wikidata.org/wiki/Q322152","display_name":"Ablation zone","level":3,"score":0.2840999960899353},{"id":"https://openalex.org/C2989005","wikidata":"https://www.wikidata.org/wiki/Q214963","display_name":"Nuclear medicine","level":1,"score":0.272599995136261}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.64898/2026.10.08.26365096","doi":"https://doi.org/10.64898/2026.10.08.26365096","is_oa":false,"landing_page_url":"https://doi.org/10.64898/2026.10.08.26365096","pdf_url":null,"source":{"id":"https://openalex.org/S3005729997","display_name":"medRxiv","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":["https://openalex.org/P4310315909"],"host_organization_lineage_names":["Cold Spring Harbor Laboratory Press"],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"medRxiv","raw_type":"posted-content"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","score":1.0,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":22,"referenced_works":["https://openalex.org/W4226412814","https://openalex.org/W4323294621","https://openalex.org/W4377010952","https://openalex.org/W4382502299","https://openalex.org/W4386203333","https://openalex.org/W4390892676","https://openalex.org/W4391736038","https://openalex.org/W4397032255","https://openalex.org/W4399425705","https://openalex.org/W4400422937","https://openalex.org/W4401688676","https://openalex.org/W4404625381","https://openalex.org/W4406508010","https://openalex.org/W4406727700","https://openalex.org/W4409758630","https://openalex.org/W4409887872","https://openalex.org/W4412489974","https://openalex.org/W4413107675","https://openalex.org/W4416079886","https://openalex.org/W7118320848","https://openalex.org/W7125537013","https://openalex.org/W7130515552"],"related_works":["https://openalex.org/W4415792366","https://openalex.org/W4409281723","https://openalex.org/W4416313810","https://openalex.org/W4412489974","https://openalex.org/W7165854882","https://openalex.org/W7170156567","https://openalex.org/W4412146857","https://openalex.org/W7162289436","https://openalex.org/W4410620980","https://openalex.org/W7164914813"],"abstract_inverted_index":{"Abstract":[0],"Background":[1],"Pulsed-field":[2],"ablation":[3,58,80,94,100,125,155],"(PFA)":[4],"has":[5,36,45],"recently":[6],"been":[7],"approved":[8],"in":[9,27,49,74,112,219],"the":[10,28,69,113,191],"USA":[11],"as":[12],"a":[13,23,37,89,120,140,180],"new":[14,25],"method":[15],"for":[16,110],"treating":[17],"atrial":[18,31,137,263],"fibrillation":[19,32],"(AF).":[20],"PFA":[21,44,82,102,157,169,194,222,233,236,269],"provides":[22],"promising":[24,47],"approach":[26],"treatment":[29],"of":[30,51,63,91,135,147,221,225],"(AF),":[33],"which":[34],"historically":[35],"high":[38],"recurrence":[39,134,217,241],"rate":[40],"post-ablation.":[41],"Of":[42],"significance,":[43],"shown":[46],"data":[48],"terms":[50],"safety":[52],"and":[53,71,95,122,127,278],"procedural":[54,70],"efficiency":[55],"to":[56,67,119,190],"radiofrequency":[57,93],"(RFA).":[59],"Objective":[60],"The":[61,130,168],"purpose":[62],"this":[64],"study":[65],"was":[66,133,171,270],"compare":[68],"health":[72],"outcomes":[73],"patients":[75,87,149,213,260],"with":[76,88,101,150,179,228,239,261,272,282],"recurrent":[77,96,151,262],"AF":[78,97,152],"undergoing":[79,98],"using":[81,156],"or":[83,103,162],"RFA.":[84],"Methods":[85],"Consecutive":[86],"history":[90],"previous":[92],"redo":[99,154],"RFA":[104,163,192,226],"were":[105,108,196,256],"included.":[106],"Patients":[107],"seen":[109,214],"follow-up":[111],"clinic":[114],"ranging":[115],"from":[116],"4":[117],"months":[118],"year":[121],"we":[123],"reported":[124],"strategy":[126],"arrhythmia":[128,138,280],"type.":[129],"primary":[131],"outcome":[132],"any":[136],"after":[139,232,242,265],"90-day":[141],"blanking":[142],"period.":[143],"Results":[144],"A":[145],"total":[146],"242":[148],"underwent":[153],"(n":[158,164],"=":[159,165],"54,":[160],"22.5%)":[161],"188,":[166],"77.5%).":[167],"cohort":[170],"younger":[172],"on":[173,215],"average":[174],"(66":[175],"vs.":[176,186],"70":[177],"years)":[178],"lower":[181,240,279],"mean":[182],"CHA2DS2-VASc":[183],"score":[184],"(2.2":[185],"3.06,":[187],"p=0.001)":[188],"compared":[189],"cohort.":[193],"procedures":[195],"shorter":[197,273],"(162\u00b153":[198],"vs":[199,208],"206\u00b160":[200],"minutes,":[201,210],"p<0.001)":[202],"but":[203],"required":[204],"more":[205],"fluoroscopy":[206,276],"(13.9\u00b18.9":[207],"8.7\u00b16.3":[209],"p<0.001).":[211],"Among":[212,259],"follow-up,":[216],"occurred":[218],"28%":[220],"versus":[223],"55%":[224],"patients,":[227],"longer":[229],"arrhythmia-free":[230],"survival":[231],"(log-rank":[234],"p=0.03).":[235],"remained":[237],"associated":[238,271],"multivariable":[243],"adjustment":[244],"(HR":[245],"0.4,":[246],"95%":[247],"CI":[248],"0.2\u20130.9,":[249],"p=0.04).":[250],"Adverse":[251],"events,":[252],"predominantly":[253],"vascular":[254],"access\u2013related,":[255],"similar.":[257],"Conclusion":[258],"arrhythmias":[264],"prior":[266],"RFA,":[267],"repeat":[268],"procedures,":[274],"greater":[275],"use,":[277],"recurrence,":[281],"comparable":[283],"safety.":[284]},"counts_by_year":[],"updated_date":"2026-11-05T12:25:35.769452","created_date":"2026-10-12T00:00:00"}