{"id":"https://openalex.org/W7221020751","doi":"https://doi.org/10.1093/bioadv/vbag304","title":"dbcan-nf: a Nextflow pipeline for accurate CAZyme annotation in metagenomes","display_name":"dbcan-nf: a Nextflow pipeline for accurate CAZyme annotation in metagenomes","publication_year":2026,"publication_date":"2026-01-01","ids":{"openalex":"https://openalex.org/W7221020751","doi":"https://doi.org/10.1093/bioadv/vbag304","pmid":"https://pubmed.ncbi.nlm.nih.gov/42899262","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/13679938"},"language":"en","primary_location":{"id":"doi:10.1093/bioadv/vbag304","doi":"https://doi.org/10.1093/bioadv/vbag304","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bioadv/vbag304","pdf_url":"https://academic.oup.com/bioinformaticsadvances/advance-article-pdf/doi/10.1093/bioadv/vbag304/71671498/vbag304.pdf","source":{"id":"https://openalex.org/S4210234069","display_name":"Bioinformatics Advances","issn_l":"2635-0041","issn":["2635-0041"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","jufo-1","ki-jl-1","norway-1","oarl"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics Advances","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://academic.oup.com/bioinformaticsadvances/advance-article-pdf/doi/10.1093/bioadv/vbag304/71671498/vbag304.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5140398203","display_name":"Xinpeng Zhang","orcid":"https://orcid.org/0000-0001-7567-8973","observed_orcids":["https://orcid.org/0000-0001-7567-8973"]},"institutions":[{"id":"https://openalex.org/I114395901","display_name":"University of Nebraska\u2013Lincoln","ror":"https://ror.org/043mer456","country_code":"US","type":"education","lineage":["https://openalex.org/I114395901"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Xinpeng Zhang","raw_affiliation_strings":["Department of Food Science and Technology, Nebraska Food for Health Center, University of Nebraska-Lincoln , Lincoln, NE 68588,"],"raw_orcid":"https://orcid.org/0000-0001-7567-8973","affiliations":[{"raw_affiliation_string":"Department of Food Science and Technology, Nebraska Food for Health Center, University of Nebraska-Lincoln , Lincoln, NE 68588,","institution_ids":["https://openalex.org/I114395901"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5036880760","display_name":"Haidong Yi","orcid":"https://orcid.org/0000-0002-2591-1922","observed_orcids":["https://orcid.org/0000-0002-2591-1922"]},"institutions":[{"id":"https://openalex.org/I1313298211","display_name":"St. Jude Children's Research Hospital","ror":"https://ror.org/02r3e0967","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1313298211","https://openalex.org/I2802152183"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Haidong Yi","raw_affiliation_strings":["St. Jude Children\u2019s Research Hospital Center for Applied Bioinformatics, , Memphis, TN 38105,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"St. Jude Children\u2019s Research Hospital Center for Applied Bioinformatics, , Memphis, TN 38105,","institution_ids":["https://openalex.org/I1313298211"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5140699185","display_name":"Jinfang Zheng","orcid":"https://orcid.org/0000-0001-5966-7713","observed_orcids":["https://orcid.org/0000-0001-5966-7713"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Jinfang Zheng","raw_affiliation_strings":["Chongqing Institute of Intelligent Medicine (CIIM) , Chongqing, 400042,"],"raw_orcid":"https://orcid.org/0000-0001-5966-7713","affiliations":[{"raw_affiliation_string":"Chongqing Institute of Intelligent Medicine (CIIM) , Chongqing, 400042,","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5100563236","display_name":"Yanbin Yin","orcid":"https://orcid.org/0000-0001-7667-881X","observed_orcids":["https://orcid.org/0000-0001-7667-881X","https://orcid.org/0000-0002-5755-5977"]},"institutions":[{"id":"https://openalex.org/I114395901","display_name":"University of Nebraska\u2013Lincoln","ror":"https://ror.org/043mer456","country_code":"US","type":"education","lineage":["https://openalex.org/I114395901"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Yanbin Yin","raw_affiliation_strings":["Department of Food Science and Technology, Nebraska Food for Health Center, University of Nebraska-Lincoln , Lincoln, NE 68588,"],"raw_orcid":"https://orcid.org/0000-0001-7667-881X","affiliations":[{"raw_affiliation_string":"Department of Food Science and Technology, Nebraska Food for Health Center, University of Nebraska-Lincoln , Lincoln, NE 68588,","institution_ids":["https://openalex.org/I114395901"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5100563236"],"corresponding_institution_ids":["https://openalex.org/I114395901"],"apc_list":{"value":2726,"currency":"USD","value_usd":2726},"apc_paid":{"value":2726,"currency":"USD","value_usd":2726},"fwci":0.0,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":{"value":0.63117179,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"6","issue":"1","first_page":"vbag304","last_page":"vbag304"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10015","display_name":"Genomics and Phylogenetic Studies","score":0.9779999852180481,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10015","display_name":"Genomics and Phylogenetic Studies","score":0.9779999852180481,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11617","display_name":"Enzyme Production and Characterization","score":0.003599999938160181,"subfield":{"id":"https://openalex.org/subfields/1305","display_name":"Biotechnology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11986","display_name":"Scientific Computing and Data Management","score":0.0017000000225380063,"subfield":{"id":"https://openalex.org/subfields/1802","display_name":"Information Systems and Management"},"field":{"id":"https://openalex.org/fields/18","display_name":"Decision Sciences"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/carbohydrate-active-enzymes","display_name":"carbohydrate-active enzymes","score":0.9070000052452087},{"id":"https://openalex.org/keywords/metagenome","display_name":"metagenome","score":0.800000011920929},{"id":"https://openalex.org/keywords/nextflow-pipeline","display_name":"Nextflow pipeline","score":0.828000009059906},{"id":"https://openalex.org/keywords/whole-genome-shotgun-sequencing","display_name":"whole genome shotgun sequencing","score":0.8669999837875366},{"id":"https://openalex.org/keywords/sequencing-depth","display_name":"sequencing depth","score":0.609000027179718},{"id":"https://openalex.org/keywords/long-reads","display_name":"long reads","score":0.46799999475479126},{"id":"https://openalex.org/keywords/carbohydrate-degradation","display_name":"carbohydrate degradation","score":0.628000020980835}],"concepts":[{"id":"https://openalex.org/C2776321320","wikidata":"https://www.wikidata.org/wiki/Q857525","display_name":"Annotation","level":2,"score":0.7628999948501587},{"id":"https://openalex.org/C43521106","wikidata":"https://www.wikidata.org/wiki/Q2165493","display_name":"Pipeline (software)","level":2,"score":0.7483999729156494},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.6901999711990356},{"id":"https://openalex.org/C48044578","wikidata":"https://www.wikidata.org/wiki/Q727490","display_name":"Scalability","level":2,"score":0.6067000031471252},{"id":"https://openalex.org/C18949551","wikidata":"https://www.wikidata.org/wiki/Q740578","display_name":"Sequence assembly","level":5,"score":0.5259000062942505},{"id":"https://openalex.org/C185798385","wikidata":"https://www.wikidata.org/wiki/Q1161707","display_name":"Benchmark (surveying)","level":2,"score":0.4287000000476837},{"id":"https://openalex.org/C177212765","wikidata":"https://www.wikidata.org/wiki/Q627335","display_name":"Workflow","level":2,"score":0.4178999960422516},{"id":"https://openalex.org/C89566754","wikidata":"https://www.wikidata.org/wiki/Q2273828","display_name":"Genome project","level":4,"score":0.41749998927116394},{"id":"https://openalex.org/C124101348","wikidata":"https://www.wikidata.org/wiki/Q172491","display_name":"Data mining","level":1,"score":0.4056999981403351},{"id":"https://openalex.org/C2778505942","wikidata":"https://www.wikidata.org/wiki/Q18344624","display_name":"Microservices","level":3,"score":0.38089999556541443},{"id":"https://openalex.org/C2908923196","wikidata":"https://www.wikidata.org/wiki/Q5205742","display_name":"Gene Annotation","level":4,"score":0.3765000104904175},{"id":"https://openalex.org/C141231307","wikidata":"https://www.wikidata.org/wiki/Q7020","display_name":"Genome","level":3,"score":0.3617999851703644},{"id":"https://openalex.org/C168167062","wikidata":"https://www.wikidata.org/wiki/Q1117970","display_name":"Component (thermodynamics)","level":2,"score":0.3589000105857849},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.3560999929904938},{"id":"https://openalex.org/C105565629","wikidata":"https://www.wikidata.org/wiki/Q1248292","display_name":"Gene prediction","level":4,"score":0.3407000005245209},{"id":"https://openalex.org/C15151743","wikidata":"https://www.wikidata.org/wiki/Q903778","display_name":"Metagenomics","level":3,"score":0.3402000069618225},{"id":"https://openalex.org/C77088390","wikidata":"https://www.wikidata.org/wiki/Q8513","display_name":"Database","level":1,"score":0.32850000262260437},{"id":"https://openalex.org/C2777904410","wikidata":"https://www.wikidata.org/wiki/Q7397","display_name":"Software","level":2,"score":0.3239000141620636},{"id":"https://openalex.org/C36464697","wikidata":"https://www.wikidata.org/wiki/Q451553","display_name":"Visualization","level":2,"score":0.32339999079704285},{"id":"https://openalex.org/C189206191","wikidata":"https://www.wikidata.org/wiki/Q222046","display_name":"Genomics","level":4,"score":0.3140999972820282},{"id":"https://openalex.org/C184898388","wikidata":"https://www.wikidata.org/wiki/Q1435712","display_name":"Pairwise comparison","level":2,"score":0.31299999356269836},{"id":"https://openalex.org/C157764524","wikidata":"https://www.wikidata.org/wiki/Q1383412","display_name":"Throughput","level":3,"score":0.3075999915599823},{"id":"https://openalex.org/C175309249","wikidata":"https://www.wikidata.org/wiki/Q725864","display_name":"Pipeline transport","level":2,"score":0.30630001425743103},{"id":"https://openalex.org/C86251818","wikidata":"https://www.wikidata.org/wiki/Q816754","display_name":"Benchmarking","level":2,"score":0.304500013589859},{"id":"https://openalex.org/C101985253","wikidata":"https://www.wikidata.org/wiki/Q1073526","display_name":"Shotgun sequencing","level":4,"score":0.2992999851703644},{"id":"https://openalex.org/C115903868","wikidata":"https://www.wikidata.org/wiki/Q80993","display_name":"Software engineering","level":1,"score":0.29440000653266907},{"id":"https://openalex.org/C180384323","wikidata":"https://www.wikidata.org/wiki/Q16335137","display_name":"Alignment-free sequence analysis","level":5,"score":0.29339998960494995},{"id":"https://openalex.org/C2780598303","wikidata":"https://www.wikidata.org/wiki/Q65921492","display_name":"Flexibility (engineering)","level":2,"score":0.2840000092983246},{"id":"https://openalex.org/C2776633867","wikidata":"https://www.wikidata.org/wiki/Q186612","display_name":"Timer","level":3,"score":0.2757999897003174},{"id":"https://openalex.org/C2779694297","wikidata":"https://www.wikidata.org/wiki/Q2888953","display_name":"Bioconductor","level":3,"score":0.27079999446868896},{"id":"https://openalex.org/C3019060180","wikidata":"https://www.wikidata.org/wiki/Q184199","display_name":"Automated method","level":2,"score":0.26510000228881836},{"id":"https://openalex.org/C2778012447","wikidata":"https://www.wikidata.org/wiki/Q1034415","display_name":"Scope (computer science)","level":2,"score":0.2630999982357025},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.2628999948501587},{"id":"https://openalex.org/C2781018962","wikidata":"https://www.wikidata.org/wiki/Q5164884","display_name":"Container (type theory)","level":2,"score":0.2614000141620636},{"id":"https://openalex.org/C198531522","wikidata":"https://www.wikidata.org/wiki/Q485146","display_name":"Sample (material)","level":2,"score":0.2567000091075897}],"mesh":[],"locations_count":3,"locations":[{"id":"doi:10.1093/bioadv/vbag304","doi":"https://doi.org/10.1093/bioadv/vbag304","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bioadv/vbag304","pdf_url":"https://academic.oup.com/bioinformaticsadvances/advance-article-pdf/doi/10.1093/bioadv/vbag304/71671498/vbag304.pdf","source":{"id":"https://openalex.org/S4210234069","display_name":"Bioinformatics Advances","issn_l":"2635-0041","issn":["2635-0041"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","jufo-1","ki-jl-1","norway-1","oarl"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics Advances","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:13679938","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC13679938/","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC13679938/pdf/vbag304.pdf","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinform Adv","raw_type":"Text"},{"id":"pmid:42899262","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/42899262","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics advances","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.1093/bioadv/vbag304","doi":"https://doi.org/10.1093/bioadv/vbag304","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bioadv/vbag304","pdf_url":"https://academic.oup.com/bioinformaticsadvances/advance-article-pdf/doi/10.1093/bioadv/vbag304/71671498/vbag304.pdf","source":{"id":"https://openalex.org/S4210234069","display_name":"Bioinformatics Advances","issn_l":"2635-0041","issn":["2635-0041"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","jufo-1","ki-jl-1","norway-1","oarl"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics Advances","raw_type":"journal-article"},"sustainable_development_goals":[],"study_designs":[],"awards":[{"id":"https://openalex.org/G3199230180","display_name":"Carbohydrate enzyme gene clusters in human gut microbiome","funder_award_id":"R01GM140370","funder_id":"https://openalex.org/F4320337354","funder_display_name":"National Institute of General Medical Sciences"},{"id":"https://openalex.org/G7016608140","display_name":null,"funder_award_id":"R01GM140370","funder_id":"https://openalex.org/F4320306114","funder_display_name":"U.S. Department of Agriculture"},{"id":"https://openalex.org/G8353590143","display_name":null,"funder_award_id":"58-8042-3-076","funder_id":"https://openalex.org/F4320306114","funder_display_name":"U.S. Department of Agriculture"},{"id":"https://openalex.org/G9000900998","display_name":"Glycan Utilization Profiling in Human Gut Microbiomes of Common Funds Data","funder_award_id":"1r03od039979-01","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"}],"funders":[{"id":"https://openalex.org/F4320306114","display_name":"U.S. Department of Agriculture","ror":"https://ror.org/01na82s61"},{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337354","display_name":"National Institute of General Medical Sciences","ror":"https://ror.org/04q48ey07"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W7221020751.pdf","grobid_xml":"https://content.openalex.org/works/W7221020751.grobid-xml"},"referenced_works_count":33,"referenced_works":["https://openalex.org/W1991497480","https://openalex.org/W2103539617","https://openalex.org/W2113679889","https://openalex.org/W2115888213","https://openalex.org/W2529838505","https://openalex.org/W2605897695","https://openalex.org/W2761566426","https://openalex.org/W2789843538","https://openalex.org/W2803787045","https://openalex.org/W2990618091","https://openalex.org/W3006653136","https://openalex.org/W3042305844","https://openalex.org/W3091506611","https://openalex.org/W3143063265","https://openalex.org/W3177500196","https://openalex.org/W3217216416","https://openalex.org/W4200175714","https://openalex.org/W4213375238","https://openalex.org/W4221074414","https://openalex.org/W4224865640","https://openalex.org/W4297498241","https://openalex.org/W4308995499","https://openalex.org/W4309305886","https://openalex.org/W4367598489","https://openalex.org/W4377293006","https://openalex.org/W4381547687","https://openalex.org/W4390765730","https://openalex.org/W4394666350","https://openalex.org/W4406799200","https://openalex.org/W4412785066","https://openalex.org/W4416715651","https://openalex.org/W7155040782","https://openalex.org/W7155552143"],"related_works":["https://openalex.org/W4390765730","https://openalex.org/W2803787045","https://openalex.org/W2761566426","https://openalex.org/W4388263226","https://openalex.org/W4367598489","https://openalex.org/W4309305886","https://openalex.org/W6920660904","https://openalex.org/W2100450322","https://openalex.org/W2103539617","https://openalex.org/W4385798023"],"abstract_inverted_index":{"Motivation:":[0],"Carbohydrate-active":[1],"enzymes":[2],"(CAZymes)":[3],"are":[4],"crucial":[5],"for":[6,81,185],"carbohydrate":[7],"degradation":[8],"in":[9,19,85],"any":[10],"ecological":[11],"environment.":[12],"However,":[13,164],"CAZyme":[14,50,83,136,152],"annotation":[15,51,84],"is":[16,159],"not":[17,59],"easy":[18],"whole-genome":[20],"shotgun":[21],"(WGS)":[22],"metagenomes,":[23],"due":[24],"to":[25],"the":[26,56,139,144,149,156],"lack":[27],"of":[28,191],"accurate,":[29],"scalable,":[30],"robust,":[31],"and":[32,43,71,102,105,109,121,130,133,195],"reproducible":[33],"workflows.":[34],"We":[35],"previously":[36],"published":[37],"dbCAN":[38],"as":[39,55,77,165],"a":[40,78,125,166,172],"web":[41],"server":[42],"associated":[44],"standalone":[45],"tool":[46,141],"run_dbcan":[47,76],"that":[48,118],"performs":[49],"with":[52,60],"assembled":[53],"genomes":[54],"input":[57],"but":[58],"raw":[61],"WGS":[62],"reads.":[63,111],"Results:":[64],"Here,":[65],"we":[66,116],"present":[67],"dbcan-nf,":[68],"an":[69],"accurate":[70,151],"scalable":[72],"Nextflow":[73],"pipeline":[74],"integrating":[75],"component":[79],"step,":[80],"automated":[82],"metagenomes.":[86],"dbcan-nf":[87,119,179],"supports":[88],"multiple":[89,192],"analytical":[90],"routes,":[91,146],"including":[92],"individual":[93],"sample":[94],"assembly":[95],"(IA),":[96],"multisample":[97],"coassembly":[98],"(CA),":[99],"assembly-free":[100],"(AF),":[101],"subsampling":[103],"(SS),":[104],"accepts":[106],"both":[107],"short":[108],"long":[110],"Using":[112],"five":[113],"benchmark":[114],"datasets,":[115],"showed":[117],"(IA":[120],"AF":[122],"routes)":[123],"had":[124,171],"much":[126],"higher":[127,173],"accuracy":[128],"(recall":[129],"F1":[131],"score)":[132],"detected":[134],"more":[135],"families":[137],"than":[138,176],"competing":[140],"Cayman.":[142,177],"Among":[143],"different":[145],"dbcan-nf-IA":[147,170],"produced":[148],"most":[150],"annotation,":[153],"especially":[154],"when":[155],"sequencing":[157],"depth":[158],"sufficient":[160],"(e.g.,":[161],">1.0":[162],"Gb).":[163],"read":[167],"assembly-based":[168],"method,":[169],"computational":[174],"cost":[175],"Finally,":[178],"leverages":[180],"Nextflow-supported":[181],"high-performance":[182],"computing":[183],"execution":[184],"workflow-level":[186],"scalability":[187],"through":[188],"concurrent":[189],"processing":[190],"samples.":[193],"Availability":[194],"implementation:":[196],"https://github.com/bcb-unl/dbcan-nf.":[197]},"counts_by_year":[],"updated_date":"2026-11-08T12:12:28.789561","created_date":"2026-10-09T00:00:00"}