{"id":"https://openalex.org/W7220992947","doi":"https://doi.org/10.3389/fnut.2026.1863436","title":"Association of nutritional\u2013immune indicators and their dynamic changes with disease severity and wound healing in diabetic foot ulcers treated by tibial transverse transport: a retrospective study","display_name":"Association of nutritional\u2013immune indicators and their dynamic changes with disease severity and wound healing in diabetic foot ulcers treated by tibial transverse transport: a retrospective study","publication_year":2026,"publication_date":"2026-10-08","ids":{"openalex":"https://openalex.org/W7220992947","doi":"https://doi.org/10.3389/fnut.2026.1863436","pmid":"https://pubmed.ncbi.nlm.nih.gov/42923346","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/13687399"},"language":"en","primary_location":{"id":"doi:10.3389/fnut.2026.1863436","doi":"https://doi.org/10.3389/fnut.2026.1863436","is_oa":true,"landing_page_url":"https://doi.org/10.3389/fnut.2026.1863436","pdf_url":"https://www.frontiersin.org/journals/nutrition/articles/10.3389/fnut.2026.1863436/pdf","source":{"id":"https://openalex.org/S2596909297","display_name":"Frontiers in Nutrition","issn_l":"2296-861X","issn":["2296-861X"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","norway-1","poland-70","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320527","host_organization_name":"Frontiers Media","host_organization_lineage":["https://openalex.org/P4310320527"],"host_organization_lineage_names":["Frontiers Media"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in Nutrition","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://www.frontiersin.org/journals/nutrition/articles/10.3389/fnut.2026.1863436/pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5121427502","display_name":"Yueyue Zhu","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I160354086","display_name":"Guangxi Medical University","ror":"https://ror.org/03dveyr97","country_code":"CN","type":"education","lineage":["https://openalex.org/I160354086"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yueyue Zhu","raw_affiliation_strings":["Collaborative Innovation Centre of Regenerative Medicine and Medical BioResource Development and Application Co-constructed by the Province and Ministry, Guangxi Medical University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Collaborative Innovation Centre of Regenerative Medicine and Medical BioResource Development and Application Co-constructed by the Province and Ministry, Guangxi Medical University","institution_ids":["https://openalex.org/I160354086"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5157953870","display_name":"Sijie Yang","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210115919","display_name":"The People's Hospital of Guangxi Zhuang Autonomous Region","ror":"https://ror.org/02aa8kj12","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210115919"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Sijie Yang","raw_affiliation_strings":["Department of Bone and Joint Surgery, The People\u2019s Hospital of Guangxi Zhuang Autonomous Region, Guangxi Academy of Medical Sciences"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Bone and Joint Surgery, The People\u2019s Hospital of Guangxi Zhuang Autonomous Region, Guangxi Academy of Medical Sciences","institution_ids":["https://openalex.org/I4210115919"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5157932416","display_name":"Zhenhong Zhu","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I3923682","display_name":"Soochow University","ror":"https://ror.org/05t8y2r12","country_code":"CN","type":"education","lineage":["https://openalex.org/I3923682"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Zhenhong Zhu","raw_affiliation_strings":["Department of Burn and Plastic Surgery, Children\u2019s Hospital of Soochow University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Burn and Plastic Surgery, Children\u2019s Hospital of Soochow University","institution_ids":["https://openalex.org/I3923682"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111319017","display_name":"Ruiqing Mo","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210126060","display_name":"First Affiliated Hospital of GuangXi Medical University","ror":"https://ror.org/030sc3x20","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210126060"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Ruiqing Mo","raw_affiliation_strings":["Department of Diabetic Foot Limb-Salvage and Ulcer Reconstruction, The First Affiliated Hospital of Guangxi Medical University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Diabetic Foot Limb-Salvage and Ulcer Reconstruction, The First Affiliated Hospital of Guangxi Medical University","institution_ids":["https://openalex.org/I4210126060"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5121435963","display_name":"Ruibin Feng","orcid":"https://orcid.org/0000-0002-7533-5767","observed_orcids":["https://orcid.org/0000-0002-7533-5767"]},"institutions":[{"id":"https://openalex.org/I4210126060","display_name":"First Affiliated Hospital of GuangXi Medical University","ror":"https://ror.org/030sc3x20","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210126060"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Ruibin Feng","raw_affiliation_strings":["Department of Diabetic Foot Limb-Salvage and Ulcer Reconstruction, The First Affiliated Hospital of Guangxi Medical University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Diabetic Foot Limb-Salvage and Ulcer Reconstruction, The First Affiliated Hospital of Guangxi Medical University","institution_ids":["https://openalex.org/I4210126060"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5129011507","display_name":"Xingyu Chen","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210126060","display_name":"First Affiliated Hospital of GuangXi Medical University","ror":"https://ror.org/030sc3x20","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210126060"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Xingyu Chen","raw_affiliation_strings":["Department of Diabetic Foot Limb-Salvage and Ulcer Reconstruction, The First Affiliated Hospital of Guangxi Medical University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Diabetic Foot Limb-Salvage and Ulcer Reconstruction, The First Affiliated Hospital of Guangxi Medical University","institution_ids":["https://openalex.org/I4210126060"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5157962154","display_name":"Dapeng Yu","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210126060","display_name":"First Affiliated Hospital of GuangXi Medical University","ror":"https://ror.org/030sc3x20","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210126060"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Dapeng Yu","raw_affiliation_strings":["Department of Diabetic Foot Limb-Salvage and Ulcer Reconstruction, The First Affiliated Hospital of Guangxi Medical University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Diabetic Foot Limb-Salvage and Ulcer Reconstruction, The First Affiliated Hospital of Guangxi Medical University","institution_ids":["https://openalex.org/I4210126060"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5141206461","display_name":"Hongjie Su","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210126060","display_name":"First Affiliated Hospital of GuangXi Medical University","ror":"https://ror.org/030sc3x20","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210126060"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Hongjie Su","raw_affiliation_strings":["Department of Diabetic Foot Limb-Salvage and Ulcer Reconstruction, The First Affiliated Hospital of Guangxi Medical University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Diabetic Foot Limb-Salvage and Ulcer Reconstruction, The First Affiliated Hospital of Guangxi Medical University","institution_ids":["https://openalex.org/I4210126060"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5141206635","display_name":"Qikai Hua","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I160354086","display_name":"Guangxi Medical University","ror":"https://ror.org/03dveyr97","country_code":"CN","type":"education","lineage":["https://openalex.org/I160354086"]},{"id":"https://openalex.org/I4210126060","display_name":"First Affiliated Hospital of GuangXi Medical University","ror":"https://ror.org/030sc3x20","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210126060"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Qikai Hua","raw_affiliation_strings":["Collaborative Innovation Centre of Regenerative Medicine and Medical BioResource Development and Application Co-constructed by the Province and Ministry, Guangxi Medical University","Department of Diabetic Foot Limb-Salvage and Ulcer Reconstruction, The First Affiliated Hospital of Guangxi Medical University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Collaborative Innovation Centre of Regenerative Medicine and Medical BioResource Development and Application Co-constructed by the Province and Ministry, Guangxi Medical University","institution_ids":["https://openalex.org/I160354086"]},{"raw_affiliation_string":"Department of Diabetic Foot Limb-Salvage and Ulcer Reconstruction, The First Affiliated Hospital of Guangxi Medical University","institution_ids":["https://openalex.org/I4210126060"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5141206635"],"corresponding_institution_ids":["https://openalex.org/I160354086","https://openalex.org/I4210126060"],"apc_list":{"value":3150,"currency":"CHF","value_usd":3801},"apc_paid":{"value":3150,"currency":"CHF","value_usd":3801},"fwci":0.0,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":{"value":0.75903854,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"13","issue":null,"first_page":"1863436","last_page":"1863436"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11227","display_name":"Diabetic Foot Ulcer Assessment and Management","score":0.9961000084877014,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11227","display_name":"Diabetic Foot Ulcer Assessment and Management","score":0.9961000084877014,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10771","display_name":"Wound Healing and Treatments","score":0.003000000026077032,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11355","display_name":"Inflammatory Biomarkers in Disease Prognosis","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/diabetic-foot-ulcer","display_name":"diabetic foot ulcer","score":0.9769999980926514},{"id":"https://openalex.org/keywords/wound-healing","display_name":"wound healing","score":0.6499999761581421},{"id":"https://openalex.org/keywords/nutritional-status","display_name":"nutritional status","score":0.5070000290870667},{"id":"https://openalex.org/keywords/immune-status","display_name":"immune status","score":0.753000020980835},{"id":"https://openalex.org/keywords/wagner-grade","display_name":"Wagner grade","score":0.7360000014305115},{"id":"https://openalex.org/keywords/disease-severity","display_name":"disease severity","score":0.7649999856948853},{"id":"https://openalex.org/keywords/preoperative-risk-stratification","display_name":"preoperative risk stratification","score":0.8889999985694885},{"id":"https://openalex.org/keywords/inflammatory-activation","display_name":"inflammatory activation","score":0.5199999809265137},{"id":"https://openalex.org/keywords/postoperative-recovery-monitoring","display_name":"postoperative recovery monitoring","score":0.5770000219345093},{"id":"https://openalex.org/keywords/prognostic-factors","display_name":"prognostic factors","score":0.5370000004768372},{"id":"https://openalex.org/keywords/cox-proportional-hazards-model","display_name":"Cox proportional hazards model","score":0.6119999885559082},{"id":"https://openalex.org/keywords/lasso","display_name":"LASSO","score":0.8410000205039978},{"id":"https://openalex.org/keywords/decision-curve-analysis","display_name":"decision curve analysis","score":0.6539999842643738}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9337999820709229},{"id":"https://openalex.org/C167135981","wikidata":"https://www.wikidata.org/wiki/Q2146302","display_name":"Retrospective cohort study","level":2,"score":0.741100013256073},{"id":"https://openalex.org/C151956035","wikidata":"https://www.wikidata.org/wiki/Q1132755","display_name":"Logistic regression","level":2,"score":0.6966000199317932},{"id":"https://openalex.org/C50382708","wikidata":"https://www.wikidata.org/wiki/Q223218","display_name":"Proportional hazards model","level":2,"score":0.6489999890327454},{"id":"https://openalex.org/C2780269544","wikidata":"https://www.wikidata.org/wiki/Q1509074","display_name":"Wound healing","level":2,"score":0.5223000049591064},{"id":"https://openalex.org/C2777858829","wikidata":"https://www.wikidata.org/wiki/Q52856","display_name":"Diabetic foot","level":3,"score":0.5083000063896179},{"id":"https://openalex.org/C555293320","wikidata":"https://www.wikidata.org/wiki/Q12206","display_name":"Diabetes mellitus","level":2,"score":0.48919999599456787},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.4846000075340271},{"id":"https://openalex.org/C2778144972","wikidata":"https://www.wikidata.org/wiki/Q52859","display_name":"Diabetic foot ulcer","level":4,"score":0.47780001163482666},{"id":"https://openalex.org/C207103383","wikidata":"https://www.wikidata.org/wiki/Q3930246","display_name":"Hazard ratio","level":3,"score":0.47360000014305115},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.3991999924182892},{"id":"https://openalex.org/C201903717","wikidata":"https://www.wikidata.org/wiki/Q1778788","display_name":"Cohort study","level":2,"score":0.37459999322891235},{"id":"https://openalex.org/C72563966","wikidata":"https://www.wikidata.org/wiki/Q1303415","display_name":"Cohort","level":2,"score":0.3637999892234802},{"id":"https://openalex.org/C76318530","wikidata":"https://www.wikidata.org/wiki/Q16833590","display_name":"Area under the curve","level":2,"score":0.350600004196167},{"id":"https://openalex.org/C146357865","wikidata":"https://www.wikidata.org/wiki/Q1123245","display_name":"Stage (stratigraphy)","level":2,"score":0.30570000410079956},{"id":"https://openalex.org/C58471807","wikidata":"https://www.wikidata.org/wiki/Q327120","display_name":"Receiver operating characteristic","level":2,"score":0.29649999737739563},{"id":"https://openalex.org/C30036603","wikidata":"https://www.wikidata.org/wiki/Q17125150","display_name":"Severity of illness","level":2,"score":0.28349998593330383},{"id":"https://openalex.org/C152877465","wikidata":"https://www.wikidata.org/wiki/Q208042","display_name":"Regression analysis","level":2,"score":0.2639000117778778}],"mesh":[],"locations_count":4,"locations":[{"id":"doi:10.3389/fnut.2026.1863436","doi":"https://doi.org/10.3389/fnut.2026.1863436","is_oa":true,"landing_page_url":"https://doi.org/10.3389/fnut.2026.1863436","pdf_url":"https://www.frontiersin.org/journals/nutrition/articles/10.3389/fnut.2026.1863436/pdf","source":{"id":"https://openalex.org/S2596909297","display_name":"Frontiers in Nutrition","issn_l":"2296-861X","issn":["2296-861X"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","norway-1","poland-70","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320527","host_organization_name":"Frontiers Media","host_organization_lineage":["https://openalex.org/P4310320527"],"host_organization_lineage_names":["Frontiers Media"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in Nutrition","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:13687399","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC13687399/","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC13687399/pdf/fnut-13-1863436.pdf","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Front Nutr","raw_type":"Text"},{"id":"pmid:42923346","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/42923346","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in nutrition","raw_type":"Journal Article"},{"id":"pmh:oai:doaj.org/article:3d2a2cfee60c4f4c9830454c6fe8b1b0","doi":null,"is_oa":false,"landing_page_url":"https://doaj.org/article/3d2a2cfee60c4f4c9830454c6fe8b1b0","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Frontiers in Nutrition, Vol 13 (2026)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.3389/fnut.2026.1863436","doi":"https://doi.org/10.3389/fnut.2026.1863436","is_oa":true,"landing_page_url":"https://doi.org/10.3389/fnut.2026.1863436","pdf_url":"https://www.frontiersin.org/journals/nutrition/articles/10.3389/fnut.2026.1863436/pdf","source":{"id":"https://openalex.org/S2596909297","display_name":"Frontiers in Nutrition","issn_l":"2296-861X","issn":["2296-861X"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","norway-1","poland-70","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320527","host_organization_name":"Frontiers Media","host_organization_lineage":["https://openalex.org/P4310320527"],"host_organization_lineage_names":["Frontiers Media"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in Nutrition","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":1.0,"display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[{"id":"https://openalex.org/G4108296566","display_name":null,"funder_award_id":"82260448","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G6170534742","display_name":null,"funder_award_id":"2023JJD140126","funder_id":"https://openalex.org/F4320322768","funder_display_name":"Natural Science Foundation of Guangxi Province"}],"funders":[{"id":"https://openalex.org/F4320321001","display_name":"National Natural Science Foundation of China","ror":"https://ror.org/01h0zpd94"},{"id":"https://openalex.org/F4320322768","display_name":"Natural Science Foundation of Guangxi Province","ror":null},{"id":"https://openalex.org/F4320336618","display_name":"Science and Technology Program of Suzhou","ror":null}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W7220992947.pdf","grobid_xml":"https://content.openalex.org/works/W7220992947.grobid-xml"},"referenced_works_count":35,"referenced_works":["https://openalex.org/W1829956932","https://openalex.org/W2010287327","https://openalex.org/W2141955497","https://openalex.org/W2587680743","https://openalex.org/W2605517955","https://openalex.org/W2930890851","https://openalex.org/W2970454757","https://openalex.org/W2993759998","https://openalex.org/W3037154077","https://openalex.org/W4200278279","https://openalex.org/W4221062413","https://openalex.org/W4225277639","https://openalex.org/W4292543961","https://openalex.org/W4304607919","https://openalex.org/W4308771245","https://openalex.org/W4312188510","https://openalex.org/W4380231791","https://openalex.org/W4382918816","https://openalex.org/W4383187331","https://openalex.org/W4387472894","https://openalex.org/W4392504542","https://openalex.org/W4392971217","https://openalex.org/W4393356566","https://openalex.org/W4400090191","https://openalex.org/W4400228599","https://openalex.org/W4402334273","https://openalex.org/W4403881204","https://openalex.org/W4406608639","https://openalex.org/W4406809896","https://openalex.org/W4409467036","https://openalex.org/W4411668165","https://openalex.org/W4412810181","https://openalex.org/W4414843382","https://openalex.org/W4415386281","https://openalex.org/W7162335835"],"related_works":["https://openalex.org/W4322622125","https://openalex.org/W4400090191","https://openalex.org/W4403881204","https://openalex.org/W4400228599","https://openalex.org/W4313585926","https://openalex.org/W4400472084","https://openalex.org/W4396820112","https://openalex.org/W7006505375","https://openalex.org/W7162010047","https://openalex.org/W4413369599"],"abstract_inverted_index":{"Background":[0],"Although":[1],"tibial":[2],"transverse":[3],"transport":[4],"(TTT)":[5],"may":[6,269,294],"promote":[7],"wound":[8,41,136,213,228,248,290],"repair":[9],"in":[10,230,250,279],"complex":[11],"diabetic":[12],"foot":[13],"ulcer":[14],"(DFU),":[15],"reliable":[16],"indicators":[17,32],"reflecting":[18],"postoperative":[19,110,212],"recovery":[20],"remain":[21],"limited.":[22],"This":[23,48],"study":[24,51],"aimed":[25],"to":[26,69,80,99,126],"investigate":[27],"the":[28,128,231,303],"association":[29,129],"of":[30,226,299],"nutritional\u2013immune":[31,82,132,153,300],"and":[33,40,62,74,94,122,134,152,169,190,206,261,268,293],"their":[34],"dynamic":[35,131],"changes":[36,133],"with":[37,85,88,107,141,183,211,222,252,265,288],"DFU":[38,54,86,143,146,184,197,266],"severity":[39,267],"healing":[42,137,214,229,249,291],"time":[43,292],"after":[44,284],"TTT":[45,58,285],"treatment.":[46],"Methods":[47],"retrospective":[49],"cohort":[50],"included":[52],"227":[53],"patients":[55,106,147,251],"who":[56],"underwent":[57],"between":[59,130],"January":[60],"2023":[61],"May":[63],"2024.":[64],"Patients":[65],"were":[66,78,113,208],"classified":[67],"according":[68],"Wagner":[70],"grades.":[71],"LASSO":[72],"regression":[73,77,157],"multivariable":[75],"logistic":[76,156],"used":[79],"identify":[81],"factors":[83],"associated":[84,182,210,221,264,287],"severity,":[87],"ROC":[89,124],"curve":[90,96],"analysis,":[91,93],"calibration":[92],"decision":[95],"analysis":[97,121,125,245],"performed":[98],"evaluate":[100,127],"model":[101,187,234],"performance.":[102],"In":[103],"addition,":[104],"147":[105],"complete":[108],"1-month":[109],"laboratory":[111],"data":[112],"analyzed":[114],"using":[115],"Cox":[116,233],"proportional":[117],"hazards":[118],"regression,":[119],"Kaplan\u2013Meier":[120,244],"time-dependent":[123],"subsequent":[135,227,289],"time.":[138],"Results":[139],"Compared":[140],"non-severe":[142],"patients,":[144],"severe":[145,196],"showed":[148,192,246],"greater":[149,217,253],"inflammatory":[150],"activation":[151],"disturbances.":[154],"Multivariable":[155],"identified":[158],"ANLR":[159,189,207,262],"(OR":[160,171],"=":[161,167,172,178,199,236,242,257],"0.993,":[162],"95%":[163,174,201,238],"CI:":[164,175,202,239],"0.987\u20130.999,":[165],"p":[166,177,241,256],"0.020)":[168],"PNI":[170,191,205,260,280],"0.909,":[173],"0.853\u20130.969,":[176],"0.004)":[179],"as":[180],"independently":[181,220],"severity.":[185],"The":[186],"incorporating":[188],"good":[193],"discrimination":[194],"for":[195,273],"(AUC":[198],"0.825,":[200],"0.756\u20130.893).":[203],"Baseline":[204],"not":[209],"time,":[215],"whereas":[216],"\u0394PNI":[218,254],"was":[219],"a":[223],"higher":[224],"hazard":[225],"severity-stratified":[232],"(HR":[235],"1.030,":[237],"1.008\u20131.053,":[240],"0.008).":[243],"faster":[247],"(log-rank":[255],"0.018).":[258],"Conclusion":[259],"are":[263],"provide":[270],"complementary":[271],"information":[272],"preoperative":[274],"risk":[275],"stratification.":[276],"An":[277],"increase":[278],"at":[281],"1":[282],"month":[283],"is":[286],"represent":[295],"an":[296],"integrated":[297],"response":[298],"status":[301],"during":[302],"treatment":[304],"course.":[305]},"counts_by_year":[],"updated_date":"2026-10-29T09:56:32.521200","created_date":"2026-10-09T00:00:00"}