{"id":"https://openalex.org/W7220975605","doi":"https://doi.org/10.48550/arxiv.2610.10102","title":"Analytical Modeling of Open- and Closed-Loop Dispersive Molecular Communication Channels with Pulsatile Flow","display_name":"Analytical Modeling of Open- and Closed-Loop Dispersive Molecular Communication Channels with Pulsatile Flow","publication_year":2026,"publication_date":"2026-10-07","ids":{"openalex":"https://openalex.org/W7220975605","doi":"https://doi.org/10.48550/arxiv.2610.10102"},"language":"en","primary_location":{"id":"pmh:oai:arXiv.org:2610.10102","doi":null,"is_oa":true,"landing_page_url":"https://arxiv.org/abs/2610.10102","pdf_url":"https://arxiv.org/pdf/2610.10102","source":{"id":"https://openalex.org/S4306400194","display_name":"arXiv (Cornell University)","issn_l":"2331-8422","issn":["2331-8422"],"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I205783295","host_organization_name":"Cornell University","host_organization_lineage":["https://openalex.org/I205783295"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"text"},"volume":null,"type":"preprint","is_traditional":true,"indexed_in":["arxiv","datacite"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://arxiv.org/pdf/2610.10102","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5133393646","display_name":"Theofilos Symeonidis","orcid":"https://orcid.org/0009-0005-6949-3362","observed_orcids":["https://orcid.org/0009-0005-6949-3362"]},"institutions":[{"id":"https://openalex.org/I181369854","display_name":"Friedrich-Alexander-Universit\u00e4t Erlangen-N\u00fcrnberg","ror":"https://ror.org/00f7hpc57","country_code":"DE","type":"education","lineage":["https://openalex.org/I181369854"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Symeonidis, Theofilos","raw_affiliation_strings":["Institute for Digital Communications , Friedrich-Alexander- Universit\u00e4t Erlangen-N\u00fcrnberg , Erlangen , Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute for Digital Communications , Friedrich-Alexander- Universit\u00e4t Erlangen-N\u00fcrnberg , Erlangen , Germany","institution_ids":["https://openalex.org/I181369854"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5054949989","display_name":"Fardad Vakilipoor","orcid":"https://orcid.org/0000-0002-1216-5385","observed_orcids":["https://orcid.org/0000-0002-1216-5385"]},"institutions":[{"id":"https://openalex.org/I181369854","display_name":"Friedrich-Alexander-Universit\u00e4t Erlangen-N\u00fcrnberg","ror":"https://ror.org/00f7hpc57","country_code":"DE","type":"education","lineage":["https://openalex.org/I181369854"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Vakilipoor, Fardad","raw_affiliation_strings":["Institute for Digital Communications , Friedrich-Alexander- Universit\u00e4t Erlangen-N\u00fcrnberg , Erlangen , Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute for Digital Communications , Friedrich-Alexander- Universit\u00e4t Erlangen-N\u00fcrnberg , Erlangen , Germany","institution_ids":["https://openalex.org/I181369854"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5114534505","display_name":"Timo Jakumeit","orcid":"https://orcid.org/0009-0007-1527-0942","observed_orcids":["https://orcid.org/0009-0007-1527-0942"]},"institutions":[{"id":"https://openalex.org/I181369854","display_name":"Friedrich-Alexander-Universit\u00e4t Erlangen-N\u00fcrnberg","ror":"https://ror.org/00f7hpc57","country_code":"DE","type":"education","lineage":["https://openalex.org/I181369854"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Jakumeit, Timo","raw_affiliation_strings":["Institute for Digital Communications , Friedrich-Alexander- Universit\u00e4t Erlangen-N\u00fcrnberg , Erlangen , Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute for Digital Communications , Friedrich-Alexander- Universit\u00e4t Erlangen-N\u00fcrnberg , Erlangen , Germany","institution_ids":["https://openalex.org/I181369854"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5139863883","display_name":"Robert Schober","orcid":"https://orcid.org/0000-0002-6420-4884","observed_orcids":["https://orcid.org/0000-0002-6420-4884"]},"institutions":[{"id":"https://openalex.org/I181369854","display_name":"Friedrich-Alexander-Universit\u00e4t Erlangen-N\u00fcrnberg","ror":"https://ror.org/00f7hpc57","country_code":"DE","type":"education","lineage":["https://openalex.org/I181369854"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Schober, Robert","raw_affiliation_strings":["Institute for Digital Communications , Friedrich-Alexander- Universit\u00e4t Erlangen-N\u00fcrnberg , Erlangen , Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute for Digital Communications , Friedrich-Alexander- Universit\u00e4t Erlangen-N\u00fcrnberg , Erlangen , Germany","institution_ids":["https://openalex.org/I181369854"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5123335149","display_name":"Nunzio Tuccitto","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I181369854","display_name":"Friedrich-Alexander-Universit\u00e4t Erlangen-N\u00fcrnberg","ror":"https://ror.org/00f7hpc57","country_code":"DE","type":"education","lineage":["https://openalex.org/I181369854"]},{"id":"https://openalex.org/I39063666","display_name":"University of Catania","ror":"https://ror.org/03a64bh57","country_code":"IT","type":"education","lineage":["https://openalex.org/I39063666"]}],"countries":["DE","IT"],"is_corresponding":false,"raw_author_name":"Tuccitto, Nunzio","raw_affiliation_strings":["Institute for Digital Communications , Friedrich-Alexander- Universit\u00e4t Erlangen-N\u00fcrnberg , Erlangen , Germany","N. Tuccitto is with the University of Catania , Catania , Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute for Digital Communications , Friedrich-Alexander- Universit\u00e4t Erlangen-N\u00fcrnberg , Erlangen , Germany","institution_ids":["https://openalex.org/I181369854"]},{"raw_affiliation_string":"N. Tuccitto is with the University of Catania , Catania , Italy","institution_ids":["https://openalex.org/I39063666"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5074561882","display_name":"Maximilian Sch\u00e4fer","orcid":"https://orcid.org/0000-0002-3332-4701","observed_orcids":["https://orcid.org/0000-0002-3332-4701"]},"institutions":[{"id":"https://openalex.org/I181369854","display_name":"Friedrich-Alexander-Universit\u00e4t Erlangen-N\u00fcrnberg","ror":"https://ror.org/00f7hpc57","country_code":"DE","type":"education","lineage":["https://openalex.org/I181369854"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Sch\u00e4fer, Maximilian","raw_affiliation_strings":["Institute for Digital Communications , Friedrich-Alexander- Universit\u00e4t Erlangen-N\u00fcrnberg , Erlangen , Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute for Digital Communications , Friedrich-Alexander- Universit\u00e4t Erlangen-N\u00fcrnberg , Erlangen , Germany","institution_ids":["https://openalex.org/I181369854"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T13052","display_name":"Molecular Communication and Nanonetworks","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T13052","display_name":"Molecular Communication and Nanonetworks","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10851","display_name":"Optical Wireless Communication Technologies","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2208","display_name":"Electrical and Electronic Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T12029","display_name":"DNA and Biological Computing","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2614","display_name":"Theoretical Computer Science"},"field":{"id":"https://openalex.org/fields/26","display_name":"Mathematics"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/molecular-communication","display_name":"molecular communication","score":0.9900000095367432},{"id":"https://openalex.org/keywords/pulsatile-blood-flow","display_name":"pulsatile blood flow","score":0.8180000185966492},{"id":"https://openalex.org/keywords/dispersive-channels","display_name":"dispersive channels","score":0.6949999928474426},{"id":"https://openalex.org/keywords/analytical-channel-model","display_name":"analytical channel model","score":0.6959999799728394},{"id":"https://openalex.org/keywords/wrapped-normal-distribution","display_name":"wrapped normal distribution","score":0.7360000014305115},{"id":"https://openalex.org/keywords/cardiovascular-system","display_name":"cardiovascular system","score":0.5989999771118164},{"id":"https://openalex.org/keywords/blood-vessel-geometry","display_name":"blood vessel geometry","score":0.4429999887943268},{"id":"https://openalex.org/keywords/hemorheology","display_name":"hemorheology","score":0.7549999952316284},{"id":"https://openalex.org/keywords/particle-simulation","display_name":"particle simulation","score":0.5109999775886536}],"concepts":[{"id":"https://openalex.org/C2779767902","wikidata":"https://www.wikidata.org/wiki/Q17037278","display_name":"Molecular communication","level":4,"score":0.9217000007629395},{"id":"https://openalex.org/C79191276","wikidata":"https://www.wikidata.org/wiki/Q7259620","display_name":"Pulsatile flow","level":2,"score":0.8794000148773193},{"id":"https://openalex.org/C69357855","wikidata":"https://www.wikidata.org/wiki/Q163214","display_name":"Diffusion","level":2,"score":0.6622999906539917},{"id":"https://openalex.org/C127162648","wikidata":"https://www.wikidata.org/wiki/Q16858953","display_name":"Channel (broadcasting)","level":2,"score":0.6355000138282776},{"id":"https://openalex.org/C38349280","wikidata":"https://www.wikidata.org/wiki/Q1434290","display_name":"Flow (mathematics)","level":2,"score":0.572700023651123},{"id":"https://openalex.org/C57879066","wikidata":"https://www.wikidata.org/wiki/Q41217","display_name":"Mechanics","level":1,"score":0.5534999966621399},{"id":"https://openalex.org/C158846371","wikidata":"https://www.wikidata.org/wiki/Q1642137","display_name":"Blood flow","level":2,"score":0.4855000078678131},{"id":"https://openalex.org/C121864883","wikidata":"https://www.wikidata.org/wiki/Q677916","display_name":"Statistical physics","level":1,"score":0.4657000005245209},{"id":"https://openalex.org/C57736034","wikidata":"https://www.wikidata.org/wiki/Q17104113","display_name":"Molecular diffusion","level":3,"score":0.44760000705718994},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.43849998712539673},{"id":"https://openalex.org/C186060115","wikidata":"https://www.wikidata.org/wiki/Q30336093","display_name":"Biological system","level":1,"score":0.4300999939441681},{"id":"https://openalex.org/C5072599","wikidata":"https://www.wikidata.org/wiki/Q379788","display_name":"Advection","level":2,"score":0.40720000863075256},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.38359999656677246},{"id":"https://openalex.org/C75755367","wikidata":"https://www.wikidata.org/wiki/Q104531076","display_name":"Equalization (audio)","level":3,"score":0.3756999969482422},{"id":"https://openalex.org/C76969082","wikidata":"https://www.wikidata.org/wiki/Q486902","display_name":"Mathematical model","level":2,"score":0.3100999891757965},{"id":"https://openalex.org/C44154836","wikidata":"https://www.wikidata.org/wiki/Q45045","display_name":"Simulation","level":1,"score":0.30869999527931213},{"id":"https://openalex.org/C101765175","wikidata":"https://www.wikidata.org/wiki/Q577764","display_name":"Communications system","level":2,"score":0.28690001368522644},{"id":"https://openalex.org/C164602753","wikidata":"https://www.wikidata.org/wiki/Q567544","display_name":"Anomalous diffusion","level":3,"score":0.28130000829696655},{"id":"https://openalex.org/C110121322","wikidata":"https://www.wikidata.org/wiki/Q865811","display_name":"Distribution (mathematics)","level":2,"score":0.27000001072883606},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.26179999113082886},{"id":"https://openalex.org/C166693061","wikidata":"https://www.wikidata.org/wiki/Q5462119","display_name":"Flow velocity","level":3,"score":0.257999986410141},{"id":"https://openalex.org/C180925781","wikidata":"https://www.wikidata.org/wiki/Q514096","display_name":"Open-channel flow","level":3,"score":0.25760000944137573}],"mesh":[],"locations_count":2,"locations":[{"id":"pmh:oai:arXiv.org:2610.10102","doi":null,"is_oa":true,"landing_page_url":"https://arxiv.org/abs/2610.10102","pdf_url":"https://arxiv.org/pdf/2610.10102","source":{"id":"https://openalex.org/S4306400194","display_name":"arXiv (Cornell University)","issn_l":"2331-8422","issn":["2331-8422"],"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I205783295","host_organization_name":"Cornell University","host_organization_lineage":["https://openalex.org/I205783295"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"text"},{"id":"doi:10.48550/arxiv.2610.10102","doi":"https://doi.org/10.48550/arxiv.2610.10102","is_oa":true,"landing_page_url":"https://doi.org/10.48550/arxiv.2610.10102","pdf_url":null,"source":{"id":"https://openalex.org/S4306400194","display_name":"arXiv (Cornell University)","issn_l":"2331-8422","issn":["2331-8422"],"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I205783295","host_organization_name":"Cornell University","host_organization_lineage":["https://openalex.org/I205783295"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Preprint"}],"best_oa_location":{"id":"pmh:oai:arXiv.org:2610.10102","doi":null,"is_oa":true,"landing_page_url":"https://arxiv.org/abs/2610.10102","pdf_url":"https://arxiv.org/pdf/2610.10102","source":{"id":"https://openalex.org/S4306400194","display_name":"arXiv (Cornell University)","issn_l":"2331-8422","issn":["2331-8422"],"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I205783295","host_organization_name":"Cornell University","host_organization_lineage":["https://openalex.org/I205783295"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"text"},"sustainable_development_goals":[],"study_designs":[],"awards":[{"id":"https://openalex.org/G4281694788","display_name":"GRK 2950: Synthetische molekulare Kommunikation \u00fcber unterschiedliche Gr\u00f6\u00dfenordnungen: Von der Theorie bis zu Experimenten","funder_award_id":"509922606","funder_id":"https://openalex.org/F4320320879","funder_display_name":"Deutsche Forschungsgemeinschaft"},{"id":"https://openalex.org/G4587792665","display_name":null,"funder_award_id":"GRK 2950","funder_id":"https://openalex.org/F4320320879","funder_display_name":"Deutsche Forschungsgemeinschaft"},{"id":"https://openalex.org/G8178504212","display_name":null,"funder_award_id":"SCHA 2350/2-1","funder_id":"https://openalex.org/F4320320879","funder_display_name":"Deutsche Forschungsgemeinschaft"},{"id":"https://openalex.org/G841117266","display_name":null,"funder_award_id":"101185661","funder_id":"https://openalex.org/F4320320300","funder_display_name":"European Commission"}],"funders":[{"id":"https://openalex.org/F4320320300","display_name":"European Commission","ror":"https://ror.org/00k4n6c32"},{"id":"https://openalex.org/F4320320879","display_name":"Deutsche Forschungsgemeinschaft","ror":"https://ror.org/018mejw64"},{"id":"https://openalex.org/F4320334322","display_name":"HORIZON EUROPE Framework Programme","ror":null}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W7220975605.pdf","grobid_xml":"https://content.openalex.org/works/W7220975605.grobid-xml"},"referenced_works_count":2,"referenced_works":["https://openalex.org/W2055473405","https://openalex.org/W7220988159"],"related_works":["https://openalex.org/W7153171517","https://openalex.org/W2767699530","https://openalex.org/W4414110678","https://openalex.org/W2905312169","https://openalex.org/W2873304218","https://openalex.org/W2948940334","https://openalex.org/W2752047120","https://openalex.org/W7092295582","https://openalex.org/W2215343205","https://openalex.org/W7095970676"],"abstract_inverted_index":{"Molecular":[0],"communication":[1,5],"(MC)":[2],"is":[3,10,49,59,121,176],"a":[4,75,92,116,139,202,211],"paradigm":[6],"in":[7],"which":[8],"information":[9],"conveyed":[11],"through":[12,115],"the":[13,31,35,42,88,101,144,150,156,159,170,180,198,215,218,224,239],"release,":[14],"propagation,":[15],"and":[16,46,53,98,106,109,131,148,179,191,253],"reception":[17],"of":[18,24,104,158,217],"molecules.":[19],"Many":[20],"envisioned":[21],"healthcare":[22],"applications":[23],"MC":[25,64,81],"are":[26,184],"expected":[27],"to":[28,112,227],"operate":[29],"inside":[30],"human":[32],"body,":[33],"where":[34],"cardiovascular":[36],"system":[37],"(CVS)":[38],"may":[39],"serve":[40],"as":[41,91,210,248],"physical":[43],"propagation":[44],"environment":[45],"molecular":[47,174],"transport":[48,175,240],"governed":[50],"by":[51],"diffusion":[52,105,190],"blood":[54,57,254],"flow.":[55,69,85],"Although":[56],"flow":[58,182],"inherently":[60],"pulsatile,":[61],"most":[62],"analytical":[63,77,220,225],"channel":[65],"models":[66],"assume":[67],"steady":[68],"In":[70],"this":[71],"paper,":[72],"we":[73],"develop":[74],"time-variant":[76,96],"model":[78,120,233],"for":[79,129,143,154,214],"dispersive":[80],"channels":[82,114],"with":[83,95],"pulsatile":[84,107],"We":[86,136],"derive":[87,138],"straight-duct":[89],"response":[90],"Normal":[93],"distribution":[94],"mean":[97],"variance,":[99],"capturing":[100],"combined":[102],"effects":[103],"flow,":[108],"extend":[110],"it":[111],"closed-loop":[113],"wrapped-Normal":[117],"representation.":[118],"The":[119],"validated":[122],"against":[123],"three-dimensional":[124],"(3D)":[125],"particle-based":[126],"simulations":[127],"(PBSs)":[128],"synthetic":[130],"physiologically":[132],"motivated":[133],"velocity":[134],"waveforms.":[135],"further":[137],"closed-form":[140],"first-order":[141],"approximation":[142],"first-arrival":[145],"peak":[146],"time":[147],"introduce":[149],"nondimensional":[151],"indicator":[152],"$S_{\\mathrm{Rx}}$":[153],"assessing":[155],"applicability":[157,216,234],"reduced":[160],"one-dimensional":[161],"(1D)":[162],"model.":[163,221],"Our":[164],"results":[165],"show":[166],"that":[167,232],"pulsatility":[168],"has":[169],"strongest":[171],"influence":[172],"when":[173],"predominantly":[177],"advective":[178],"temporal":[181],"variations":[183],"not":[185,236],"averaged":[186],"out,":[187],"whereas":[188],"stronger":[189],"faster":[192],"pulsations":[193],"reduce":[194],"its":[195],"impact":[196],"on":[197,238,244],"received":[199],"signal.":[200],"Moreover,":[201],"PBS-based":[203],"parameter":[204],"sweep":[205],"supports":[206],"$S_{\\mathrm{Rx}}":[207],"\\ge":[208],"2$":[209],"practical":[212],"criterion":[213],"proposed":[219],"Finally,":[222],"relating":[223],"assumptions":[226],"representative":[228],"blood-vessel":[229],"classes":[230],"shows":[231],"depends":[235],"only":[237],"conditions":[241],"but":[242],"also":[243],"physiological":[245],"properties":[246],"such":[247],"vessel":[249],"rigidity,":[250],"geometric":[251],"uniformity,":[252],"rheology.":[255]},"counts_by_year":[],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2026-10-09T00:00:00"}