{"id":"https://openalex.org/W7220898438","doi":"https://doi.org/10.1161/res.139.suppl_1.wed079","title":"Abstract Wed079: Demographic Trends and Disparities in Mortality From Sudden Cardiac Death and Heart Failure Among Middle-Aged and Older Adults: A U.S. National Analysis (1999\u20132020)","display_name":"Abstract Wed079: Demographic Trends and Disparities in Mortality From Sudden Cardiac Death and Heart Failure Among Middle-Aged and Older Adults: A U.S. National Analysis (1999\u20132020)","publication_year":2026,"publication_date":"2026-07-17","ids":{"openalex":"https://openalex.org/W7220898438","doi":"https://doi.org/10.1161/res.139.suppl_1.wed079"},"language":"en","primary_location":{"id":"doi:10.1161/res.139.suppl_1.wed079","doi":"https://doi.org/10.1161/res.139.suppl_1.wed079","is_oa":false,"landing_page_url":"https://doi.org/10.1161/res.139.suppl_1.wed079","pdf_url":null,"source":{"id":"https://openalex.org/S10652568","display_name":"Circulation Research","issn_l":"0009-7330","issn":["0009-7330","1524-4571"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Circulation Research","raw_type":"journal-article"},"volume":null,"type":"conference-abstract","is_traditional":false,"indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5107495014","display_name":"Madiha Kiyani","orcid":"https://orcid.org/0009-0007-8812-9958","observed_orcids":["https://orcid.org/0009-0007-8812-9958"]},"institutions":[{"id":"https://openalex.org/I184565670","display_name":"Georgetown University","ror":"https://ror.org/05vzafd60","country_code":"US","type":"education","lineage":["https://openalex.org/I184565670"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Madiha Kiyani","raw_affiliation_strings":["Medstar Georgetown University, Baltimore, California, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Medstar Georgetown University, Baltimore, California, United States","institution_ids":["https://openalex.org/I184565670"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101593199","display_name":"Masab Ali","orcid":"https://orcid.org/0009-0007-8599-6861","observed_orcids":["https://orcid.org/0009-0007-8599-6861"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Masab Ali","raw_affiliation_strings":["Faisalabad Medical University, Faisalabad, Punjab, Pakistan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Faisalabad Medical University, Faisalabad, Punjab, Pakistan","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109746672","display_name":"Muhammad Abdullah","orcid":"https://orcid.org/0009-0001-4597-1412","observed_orcids":["https://orcid.org/0009-0001-4597-1412"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Muhammad Abdullah","raw_affiliation_strings":["Faisalabad Medical University, Faisalabad, Punjab, Pakistan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Faisalabad Medical University, Faisalabad, Punjab, Pakistan","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5157986029","display_name":"Ali Ashraf","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Ali Ashraf","raw_affiliation_strings":["Faisalabad Medical University, Faisalabad, Punjab, Pakistan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Faisalabad Medical University, Faisalabad, Punjab, Pakistan","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5157986533","display_name":"Muhammad Hassan","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Muhammad Hassan","raw_affiliation_strings":["Faisalabad Medical University, Faisalabad, Punjab, Pakistan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Faisalabad Medical University, Faisalabad, Punjab, Pakistan","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5061883254","display_name":"Taha Mehmood","orcid":"https://orcid.org/0009-0008-8221-3814","observed_orcids":["https://orcid.org/0009-0008-8221-3814"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Taha Mehmood","raw_affiliation_strings":["Faisalabad Medical University, Faisalabad, Punjab, Pakistan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Faisalabad Medical University, Faisalabad, Punjab, Pakistan","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5153699276","display_name":"Amina Jamil","orcid":"https://orcid.org/0009-0000-3803-8088","observed_orcids":["https://orcid.org/0009-0000-3803-8088"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Amina Jamil","raw_affiliation_strings":["Aziz Fatima Medical and Dental College, Faisalabad, Punjab, Pakistan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Aziz Fatima Medical and Dental College, Faisalabad, Punjab, Pakistan","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":"139","issue":"Suppl_1","first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10217","display_name":"Cardiac electrophysiology and arrhythmias","score":0.5054000020027161,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10217","display_name":"Cardiac electrophysiology and arrhythmias","score":0.5054000020027161,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10198","display_name":"Heart Failure Treatment and Management","score":0.2329999953508377,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12935","display_name":"Healthcare Systems and Public Health","score":0.08789999783039093,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/sudden-cardiac-death","display_name":"sudden cardiac death","score":1.0},{"id":"https://openalex.org/keywords/heart-failure","display_name":"heart failure","score":0.9990000128746033},{"id":"https://openalex.org/keywords/cardiovascular-mortality","display_name":"cardiovascular mortality","score":0.734000027179718},{"id":"https://openalex.org/keywords/demographic-disparities","display_name":"demographic disparities","score":0.6809999942779541},{"id":"https://openalex.org/keywords/racial-and-ethnic-disparities","display_name":"racial and ethnic disparities","score":0.6890000104904175},{"id":"https://openalex.org/keywords/sex-differences","display_name":"sex differences","score":0.828000009059906},{"id":"https://openalex.org/keywords/middle-aged-adults","display_name":"middle-aged adults","score":0.6639999747276306},{"id":"https://openalex.org/keywords/older-adults","display_name":"older adults","score":0.9980000257492065},{"id":"https://openalex.org/keywords/urban-rural-differences","display_name":"urban-rural differences","score":0.7889999747276306},{"id":"https://openalex.org/keywords/mortality-trends","display_name":"mortality trends","score":0.6539999842643738},{"id":"https://openalex.org/keywords/age-adjusted-mortality-rates","display_name":"age-adjusted mortality rates","score":0.7009999752044678},{"id":"https://openalex.org/keywords/place-of-death","display_name":"place of death","score":0.6430000066757202},{"id":"https://openalex.org/keywords/census-regions","display_name":"census regions","score":0.5720000267028809},{"id":"https://openalex.org/keywords/united-states","display_name":"United States","score":0.4359999895095825},{"id":"https://openalex.org/keywords/death-certificates","display_name":"death certificates","score":0.42800000309944153},{"id":"https://openalex.org/keywords/icd-10-coding","display_name":"ICD-10 coding","score":0.6690000295639038}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8389999866485596},{"id":"https://openalex.org/C2778198053","wikidata":"https://www.wikidata.org/wiki/Q181754","display_name":"Heart failure","level":2,"score":0.6179999709129333},{"id":"https://openalex.org/C149923435","wikidata":"https://www.wikidata.org/wiki/Q37732","display_name":"Demography","level":1,"score":0.6067000031471252},{"id":"https://openalex.org/C179755657","wikidata":"https://www.wikidata.org/wiki/Q58702","display_name":"Mortality rate","level":2,"score":0.5947999954223633},{"id":"https://openalex.org/C2775935837","wikidata":"https://www.wikidata.org/wiki/Q202837","display_name":"Sudden cardiac death","level":2,"score":0.5546000003814697},{"id":"https://openalex.org/C2908647359","wikidata":"https://www.wikidata.org/wiki/Q2625603","display_name":"Population","level":2,"score":0.475600004196167},{"id":"https://openalex.org/C29374701","wikidata":"https://www.wikidata.org/wiki/Q1931388","display_name":"Cause of death","level":3,"score":0.420199990272522},{"id":"https://openalex.org/C44249647","wikidata":"https://www.wikidata.org/wiki/Q208498","display_name":"Confidence interval","level":2,"score":0.3849000036716461},{"id":"https://openalex.org/C74909509","wikidata":"https://www.wikidata.org/wiki/Q10387","display_name":"Gerontology","level":1,"score":0.35690000653266907},{"id":"https://openalex.org/C2993353509","wikidata":"https://www.wikidata.org/wiki/Q411867","display_name":"Sudden death","level":2,"score":0.3165999948978424},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.3149999976158142},{"id":"https://openalex.org/C205545832","wikidata":"https://www.wikidata.org/wiki/Q17156455","display_name":"Young adult","level":2,"score":0.30079999566078186},{"id":"https://openalex.org/C2777984932","wikidata":"https://www.wikidata.org/wiki/Q7336293","display_name":"Risk of mortality","level":2,"score":0.29980000853538513},{"id":"https://openalex.org/C52130261","wikidata":"https://www.wikidata.org/wiki/Q39825","display_name":"Census","level":3,"score":0.295199990272522},{"id":"https://openalex.org/C107130276","wikidata":"https://www.wikidata.org/wiki/Q133805","display_name":"Epidemiology","level":2,"score":0.28040000796318054},{"id":"https://openalex.org/C2779874844","wikidata":"https://www.wikidata.org/wiki/Q1967281","display_name":"National Health and Nutrition Examination Survey","level":3,"score":0.2680000066757202},{"id":"https://openalex.org/C48718317","wikidata":"https://www.wikidata.org/wiki/Q4691855","display_name":"Age adjustment","level":3,"score":0.2630000114440918},{"id":"https://openalex.org/C187212893","wikidata":"https://www.wikidata.org/wiki/Q123028","display_name":"Pediatrics","level":1,"score":0.25540000200271606},{"id":"https://openalex.org/C3018792137","wikidata":"https://www.wikidata.org/wiki/Q6914399","display_name":"Excess mortality","level":3,"score":0.25429999828338623}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1161/res.139.suppl_1.wed079","doi":"https://doi.org/10.1161/res.139.suppl_1.wed079","is_oa":false,"landing_page_url":"https://doi.org/10.1161/res.139.suppl_1.wed079","pdf_url":null,"source":{"id":"https://openalex.org/S10652568","display_name":"Circulation Research","issn_l":"0009-7330","issn":["0009-7330","1524-4571"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Circulation Research","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":1.0,"display_name":"Good health and well-being"},{"id":"https://metadata.un.org/sdg/10","score":0.7578999996185303,"display_name":"Reduced inequalities"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W4404323638","https://openalex.org/W4415792573","https://openalex.org/W7164124569","https://openalex.org/W4405550346","https://openalex.org/W4414128675","https://openalex.org/W7123363919","https://openalex.org/W7215079023","https://openalex.org/W4288051600","https://openalex.org/W4409563577","https://openalex.org/W4224987321"],"abstract_inverted_index":{"Introduction:":[0],"Sudden":[1],"cardiac":[2],"death":[3,90,92,96],"(SCD)":[4],"and":[5,28,44,53,74,83,112,122,160,245,289,329,352,369],"heart":[6],"failure":[7],"(HF)":[8],"are":[9],"major":[10],"contributors":[11],"to":[12,50,66,148,157,174,326,338,372],"cardiovascular":[13,366],"mortality":[14,48,63,103,193,231,253,266,342],"in":[15,47,79,172,176,265,285,320],"the":[16,32,37,163,200,229,286,300,303,314],"United":[17],"States,":[18],"particularly":[19],"among":[20,69,344],"aging":[21],"populations.":[22],"HF":[23,54,84,330],"is":[24],"associated":[25],"with":[26,134,197,216,273,340],"structural":[27],"electrical":[29],"remodeling":[30],"of":[31,39,89,95,120,152,310,354],"heart,":[33],"which":[34,80],"substantially":[35,208],"increases":[36],"risk":[38],"SCD.":[40],"However,":[41],"national":[42],"trends":[43,126],"demographic":[45],"disparities":[46],"due":[49,325],"concurrent":[51],"SCD":[52,82,159,328],"remain":[55],"poorly":[56],"characterized.":[57],"Methods:":[58],"We":[59],"analyzed":[60],"CDC":[61],"WONDER":[62],"data":[64],"(1999\u20132020)":[65],"identify":[67],"deaths":[68,154,311],"U.S.":[70],"middle-aged":[71,217],"(55\u201374":[72],"years)":[73,78],"older":[75,346],"adults":[76,206,218],"(\u226575":[77],"both":[81],"were":[85,97,109,127,155,283],"listed":[86],"as":[87],"causes":[88],"on":[91],"certificates.":[93],"Causes":[94],"identified":[98],"using":[99,129],"ICD-10":[100],"codes.":[101],"Age-adjusted":[102],"rates":[104,194,254,305],"(AAMRs)":[105],"per":[106,170],"100,000":[107,171],"population":[108],"calculated":[110],"overall":[111,164,306,334],"stratified":[113],"by":[114,235],"sex,":[115],"age":[116],"group,":[117],"race/ethnicity,":[118],"place":[119],"death,":[121],"Census":[123],"region.":[124],"Temporal":[125],"assessed":[128],"annual":[130],"percent":[131],"changes":[132],"(APCs)":[133],"95%":[135,212,220],"confidence":[136],"intervals.":[137],"A":[138],"p-value":[139],"<0.05":[140],"was":[141,181],"considered":[142],"statistically":[143],"significant.":[144],"Results:":[145],"From":[146],"1999":[147,173,337],"2020,":[149,177,339],"a":[150,178,262,332],"total":[151],"26,030":[153],"attributed":[156],"coexisting":[158,327],"HF.":[161],"Although":[162],"AAMR":[165,201],"declined":[166],"slightly":[167],"from":[168,336,364],"0.73":[169],"0.65":[175],"significant":[179],"decrease":[180],"observed":[182,343],"until":[183],"2018":[184],"(APC:":[185,267,276],"\u22121.66%,":[186],"p":[187,269,278],"<":[188,270,279],"0.05).":[189,280],"Males":[190],"had":[191,207,228,251,294],"higher":[192,209,252,341],"than":[195,255],"females,":[196],"nearly":[198],"twice":[199],"(0.81":[202],"vs":[203],"0.44).":[204],"Older":[205],"AAMRs":[210,282,297],"(2.49;":[211],"CI,":[213,221],"2.46\u20132.52)":[214],"compared":[215,272],"(0.32;":[219],"0.31\u20130.33).":[222],"By":[223],"race,":[224],"non-Hispanic":[225],"(NH)":[226],"Blacks":[227],"highest":[230,284],"rate":[232],"(1.0),":[233],"followed":[234],"NH":[236,240,246],"American":[237],"Indians":[238],"(0.59),":[239],"Whites":[241],"(0.58),":[242],"Hispanics":[243],"(0.25),":[244],"Asians":[247],"(0.19).":[248],"Rural":[249],"areas":[250,260,275],"urban":[256,259],"areas;":[257],"however,":[258],"experienced":[261],"steeper":[263],"increase":[264],"+14.0%,":[268],"0.05)":[271],"rural":[274,355],"+1.92%,":[277],"Regionally,":[281],"South":[287],"(0.78)":[288],"Midwest":[290],"(0.69).":[291],"The":[292],"Northeast":[293],"relatively":[295],"lower":[296],"(0.40),":[298],"while":[299],"West":[301],"maintained":[302],"lowest":[304],"(0.38).":[307],"Additionally,":[308],"39%":[309],"occurred":[312,319],"at":[313],"decedent\u2019s":[315],"home,":[316],"whereas":[317],"36%":[318],"medical":[321],"facilities.":[322],"Conclusion:":[323],"Mortality":[324],"showed":[331],"modest":[333],"decline":[335],"males,":[345],"adults,":[347],"non":[348],"hispanic":[349],"black":[350],"individuals,":[351],"residents":[353],"regions.":[356],"These":[357],"findings":[358],"highlight":[359],"populations":[360],"that":[361],"may":[362],"benefit":[363],"targeted":[365],"prevention":[367],"strategies":[368],"improved":[370],"access":[371],"care.":[373]},"counts_by_year":[],"updated_date":"2026-10-26T11:51:55.731654","created_date":"2026-10-09T00:00:00"}