{"id":"https://openalex.org/W7220848486","doi":"https://doi.org/10.4103/bvjd.bvjd_59_26","title":"Comparative Evaluation of Erythritol and Glycine in Piezo-assisted Guided Biofilm Therapy: A Randomized Controlled Clinical Trial","display_name":"Comparative Evaluation of Erythritol and Glycine in Piezo-assisted Guided Biofilm Therapy: A Randomized Controlled Clinical Trial","publication_year":2026,"publication_date":"2026-07-01","ids":{"openalex":"https://openalex.org/W7220848486","doi":"https://doi.org/10.4103/bvjd.bvjd_59_26"},"language":"en","primary_location":{"id":"doi:10.4103/bvjd.bvjd_59_26","doi":"https://doi.org/10.4103/bvjd.bvjd_59_26","is_oa":true,"landing_page_url":"https://doi.org/10.4103/bvjd.bvjd_59_26","pdf_url":null,"source":{"id":"https://openalex.org/S5407047077","display_name":"Bharati Vidyapeeth Journal of Dentistry and Allied Sciences","issn_l":"3048-5398","issn":["3048-5398","3050-9904"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bharati Vidyapeeth Journal of Dentistry and Allied Sciences","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://doi.org/10.4103/bvjd.bvjd_59_26","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5157866313","display_name":"Vemula Niharika","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Vemula Niharika","raw_affiliation_strings":["Department of Periodontics, Lenora Institiute of Dental Sciences, Rajahmundry, Andhra Pradesh, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Periodontics, Lenora Institiute of Dental Sciences, Rajahmundry, Andhra Pradesh, India","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5157845196","display_name":"Sushma Sree Neeli","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Sushma Sree Neeli","raw_affiliation_strings":["Department of Periodontics, Lenora Institiute of Dental Sciences, Rajahmundry, Andhra Pradesh, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Periodontics, Lenora Institiute of Dental Sciences, Rajahmundry, Andhra Pradesh, India","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5093276641","display_name":"Anusha Gummadi","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Gummadi Anusha","raw_affiliation_strings":["Department of Periodontics, Lenora Institiute of Dental Sciences, Rajahmundry, Andhra Pradesh, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Periodontics, Lenora Institiute of Dental Sciences, Rajahmundry, Andhra Pradesh, India","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5016742453","display_name":"Santhi Gorle","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Gorle Santhi","raw_affiliation_strings":["Department of Periodontics, Lenora Institiute of Dental Sciences, Rajahmundry, Andhra Pradesh, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Periodontics, Lenora Institiute of Dental Sciences, Rajahmundry, Andhra Pradesh, India","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5121685611","display_name":"Bharath Simha Reddy Dalli","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Bharath Simha Reddy Dalli","raw_affiliation_strings":["Department of Periodontics, Lenora Institiute of Dental Sciences, Rajahmundry, Andhra Pradesh, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Periodontics, Lenora Institiute of Dental Sciences, Rajahmundry, Andhra Pradesh, India","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5065108593","display_name":"Sowmya Reddy Nandipati","orcid":"https://orcid.org/0000-0001-8458-2965","observed_orcids":["https://orcid.org/0000-0001-8458-2965"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Sowmya Reddy Nandipati","raw_affiliation_strings":["Department of Periodontics, Lenora Institiute of Dental Sciences, Rajahmundry, Andhra Pradesh, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Periodontics, Lenora Institiute of Dental Sciences, Rajahmundry, Andhra Pradesh, India","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.0,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"3","issue":"3","first_page":"102","last_page":"109"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10257","display_name":"Oral microbiology and periodontitis research","score":0.9922000169754028,"subfield":{"id":"https://openalex.org/subfields/3506","display_name":"Periodontics"},"field":{"id":"https://openalex.org/fields/35","display_name":"Dentistry"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10257","display_name":"Oral microbiology and periodontitis research","score":0.9922000169754028,"subfield":{"id":"https://openalex.org/subfields/3506","display_name":"Periodontics"},"field":{"id":"https://openalex.org/fields/35","display_name":"Dentistry"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11570","display_name":"Periodontal Regeneration and Treatments","score":0.0027000000700354576,"subfield":{"id":"https://openalex.org/subfields/3506","display_name":"Periodontics"},"field":{"id":"https://openalex.org/fields/35","display_name":"Dentistry"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11566","display_name":"Laser Applications in Dentistry and Medicine","score":0.0006000000284984708,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/erythritol","display_name":"erythritol","score":0.9980000257492065},{"id":"https://openalex.org/keywords/glycine","display_name":"glycine","score":0.9980000257492065},{"id":"https://openalex.org/keywords/guided-biofilm-therapy","display_name":"guided biofilm therapy","score":0.906000018119812},{"id":"https://openalex.org/keywords/scaling-and-root-planing","display_name":"scaling and root planing","score":0.7390000224113464},{"id":"https://openalex.org/keywords/dental-plaque-reduction","display_name":"plaque reduction","score":0.6449999809265137},{"id":"https://openalex.org/keywords/gingivitis","display_name":"gingivitis","score":0.8500000238418579},{"id":"https://openalex.org/keywords/non-surgical-periodontal-therapy","display_name":"non-surgical periodontal therapy","score":0.878000020980835},{"id":"https://openalex.org/keywords/oral-hygiene","display_name":"oral hygiene","score":0.3779999911785126}],"concepts":[{"id":"https://openalex.org/C2779626320","wikidata":"https://www.wikidata.org/wiki/Q421873","display_name":"Erythritol","level":2,"score":0.9247000217437744},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.6657000184059143},{"id":"https://openalex.org/C199343813","wikidata":"https://www.wikidata.org/wiki/Q12128","display_name":"Dentistry","level":1,"score":0.629800021648407},{"id":"https://openalex.org/C2777756961","wikidata":"https://www.wikidata.org/wiki/Q620730","display_name":"Glycine","level":3,"score":0.5659999847412109},{"id":"https://openalex.org/C58123911","wikidata":"https://www.wikidata.org/wiki/Q467410","display_name":"Biofilm","level":3,"score":0.5598000288009644},{"id":"https://openalex.org/C535046627","wikidata":"https://www.wikidata.org/wiki/Q30612","display_name":"Clinical trial","level":2,"score":0.5435000061988831},{"id":"https://openalex.org/C515851188","wikidata":"https://www.wikidata.org/wiki/Q13445028","display_name":"Oral hygiene","level":2,"score":0.5396000146865845},{"id":"https://openalex.org/C168563851","wikidata":"https://www.wikidata.org/wiki/Q1436668","display_name":"Randomized controlled trial","level":2,"score":0.507099986076355},{"id":"https://openalex.org/C2777785397","wikidata":"https://www.wikidata.org/wiki/Q492194","display_name":"Group B","level":2,"score":0.38929998874664307},{"id":"https://openalex.org/C63363279","wikidata":"https://www.wikidata.org/wiki/Q5133848","display_name":"Clinical significance","level":2,"score":0.38199999928474426},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.36070001125335693},{"id":"https://openalex.org/C2779914569","wikidata":"https://www.wikidata.org/wiki/Q143504","display_name":"Dental plaque","level":2,"score":0.3359000086784363},{"id":"https://openalex.org/C65409693","wikidata":"https://www.wikidata.org/wiki/Q425265","display_name":"Statistical significance","level":2,"score":0.33500000834465027},{"id":"https://openalex.org/C2992053201","wikidata":"https://www.wikidata.org/wiki/Q2585693","display_name":"Clinical efficacy","level":2,"score":0.3305000066757202},{"id":"https://openalex.org/C2986587452","wikidata":"https://www.wikidata.org/wiki/Q938438","display_name":"Statistical analysis","level":2,"score":0.319599986076355},{"id":"https://openalex.org/C2780385504","wikidata":"https://www.wikidata.org/wiki/Q520127","display_name":"Periodontitis","level":2,"score":0.2935999929904938},{"id":"https://openalex.org/C90924648","wikidata":"https://www.wikidata.org/wiki/Q120569","display_name":"Gastroenterology","level":1,"score":0.2904999852180481},{"id":"https://openalex.org/C2780791200","wikidata":"https://www.wikidata.org/wiki/Q673083","display_name":"Gingivitis","level":2,"score":0.2870999872684479},{"id":"https://openalex.org/C111335779","wikidata":"https://www.wikidata.org/wiki/Q3454686","display_name":"Reduction (mathematics)","level":2,"score":0.27239999175071716},{"id":"https://openalex.org/C58747440","wikidata":"https://www.wikidata.org/wiki/Q1059860","display_name":"Gingival and periodontal pocket","level":3,"score":0.26669999957084656},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.26030001044273376}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.4103/bvjd.bvjd_59_26","doi":"https://doi.org/10.4103/bvjd.bvjd_59_26","is_oa":true,"landing_page_url":"https://doi.org/10.4103/bvjd.bvjd_59_26","pdf_url":null,"source":{"id":"https://openalex.org/S5407047077","display_name":"Bharati Vidyapeeth Journal of Dentistry and Allied Sciences","issn_l":"3048-5398","issn":["3048-5398","3050-9904"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bharati Vidyapeeth Journal of Dentistry and Allied Sciences","raw_type":"journal-article"}],"best_oa_location":{"id":"doi:10.4103/bvjd.bvjd_59_26","doi":"https://doi.org/10.4103/bvjd.bvjd_59_26","is_oa":true,"landing_page_url":"https://doi.org/10.4103/bvjd.bvjd_59_26","pdf_url":null,"source":{"id":"https://openalex.org/S5407047077","display_name":"Bharati Vidyapeeth Journal of Dentistry and Allied Sciences","issn_l":"3048-5398","issn":["3048-5398","3050-9904"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bharati Vidyapeeth Journal of Dentistry and Allied Sciences","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.9940000176429749,"display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/randomized-controlled-trial","display_name":"Randomized Controlled Trial"},{"id":"https://openalex.org/study-designs/clinical-trial","display_name":"Clinical Trial"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":26,"referenced_works":["https://openalex.org/W1569659387","https://openalex.org/W1922518545","https://openalex.org/W1947627842","https://openalex.org/W1978657353","https://openalex.org/W1979357338","https://openalex.org/W2003469771","https://openalex.org/W2018904440","https://openalex.org/W2023972394","https://openalex.org/W2046426871","https://openalex.org/W2067354447","https://openalex.org/W2070300719","https://openalex.org/W2081514425","https://openalex.org/W2085100945","https://openalex.org/W2098594679","https://openalex.org/W2106671334","https://openalex.org/W2109833361","https://openalex.org/W2121671563","https://openalex.org/W2137090978","https://openalex.org/W2141275153","https://openalex.org/W2144440398","https://openalex.org/W2147331510","https://openalex.org/W2180757076","https://openalex.org/W2741223751","https://openalex.org/W2898616812","https://openalex.org/W3180758699","https://openalex.org/W4211140636"],"related_works":["https://openalex.org/W3180758699","https://openalex.org/W1978657353","https://openalex.org/W4412685895","https://openalex.org/W3163779876","https://openalex.org/W2281244281","https://openalex.org/W7202137940","https://openalex.org/W4283687004","https://openalex.org/W3117954653","https://openalex.org/W3185572031","https://openalex.org/W106450686"],"abstract_inverted_index":{"Abstract":[0],"Objectives:":[1],"To":[2],"compare":[3],"and":[4,10,18,68,102,115,142,162,166,169,194,204,217],"evaluate":[5,146],"the":[6,29,54,110,147,158,236,254],"efficacy":[7],"of":[8,22,128,149,238],"erythritol":[9,100,215,255,265],"glycine":[11,106,202,219,270],"by":[12,120],"piezo-assisted":[13],"guided":[14],"biofilm":[15,89,262],"therapy.":[16,155],"Materials":[17],"Methods:":[19],"A":[20,40,92],"total":[21],"30":[23],"eligible":[24],"patients":[25],"were":[26,34,74,118,137,160],"recruited":[27],"for":[28,60,87],"study.":[30],"The":[31],"study":[32],"participants":[33,159],"randomly":[35],"assigned":[36],"to":[37,48,109,145,187,231],"either":[38],"Group":[39,44,91,103,193],"(Erythritol":[41],"group)":[42,47],"or":[43],"B":[45,104],"(Glycine":[46],"ensure":[49],"an":[50,96],"unbiased":[51],"distribution":[52],"between":[53],"two":[55],"treatment":[56,86],"groups.":[57],"At":[58],"baseline,":[59],"all":[61],"participants,":[62],"comprehensive":[63],"periodontal":[64,154,274],"screening":[65],"was":[66,83,93,251],"performed,":[67],"plaque":[69],"index,":[70],"gingival":[71],"index":[72],"(GI)":[73],"assessed.":[75],"After":[76],"initial":[77],"screening,":[78],"disclosing":[79],"agent":[80],"(ALPHA":[81],"PLAC)":[82],"applied":[84],"before":[85],"targeted":[88],"removal.":[90],"treated":[94],"with":[95,105,258,264],"AIRFLOW\u00ae":[97],"device":[98],"using":[99],"powder,":[101,107],"according":[108],"manufacturer\u2019s":[111],"protocol.":[112],"Both":[113,241],"supragingival":[114],"subgingival":[116],"polishing":[117],"performed":[119],"a":[121,245],"single":[122],"calibrated":[123],"operator.":[124],"Participants":[125],"received":[126],"reinforcement":[127],"oral":[129],"hygiene":[130],"instructions":[131],"at":[132,139,164,229,235],"each":[133],"visit.":[134],"Clinical":[135],"parameters":[136],"reassessed":[138],"1":[140,167],"month":[141,168],"3":[143,170,239],"months":[144],"effectiveness":[148],"both":[150,175],"powders":[151],"in":[152,180,191,201,214,218,253,271],"nonsurgical":[153],"Results:":[156],"All":[157],"evaluated":[161],"examined":[163],"baseline":[165,230],"months,":[171],"On":[172],"statistical":[173],"evaluation":[174],"groups":[176,242],"showed":[177,222],"significant":[178,223,246],"reduction":[179,224],"Plaque":[181],"score":[182],"from":[183,195,208,225],"2.21":[184,196],"\u00b1":[185,189,197,199,210,212,227,233],"0.402":[186],"1.09":[188],"0.242":[190],"Erythritol":[192],"0.348\u20131.38":[198],"0.243":[200],"group":[203,216,220,256],"GI":[205],"Score":[206],"reduced":[207],"1.81":[209],"0.348\u20130.9":[211],"0.283":[213],"it":[221],"1.90":[226],"0.359":[228],"1.23":[232],"0.379":[234],"end":[237],"months.":[240],"have":[243],"shown":[244],"difference;":[247],"however,":[248],"greater":[249],"improvement":[250],"noted":[252],"compared":[257],"glycine.":[259],"Conclusion:":[260],"Piezo-assisted":[261],"removal":[263],"is":[266],"more":[267],"effective":[268],"than":[269],"enhancing":[272],"clinical":[273],"outcomes.":[275]},"counts_by_year":[],"updated_date":"2026-10-26T11:51:55.731654","created_date":"2026-10-08T00:00:00"}