{"id":"https://openalex.org/W7220832259","doi":"https://doi.org/10.1016/j.xagr.2026.100706","title":"Rare primary bilateral ovarian myeloid sarcoma preceding acute myeloid leukemia: ovarian-sparing management with long-term ovarian function and pregnancy after allogeneic hematopoietic stem cell transplantation\u2014a case report","display_name":"Rare primary bilateral ovarian myeloid sarcoma preceding acute myeloid leukemia: ovarian-sparing management with long-term ovarian function and pregnancy after allogeneic hematopoietic stem cell transplantation\u2014a case report","publication_year":2026,"publication_date":"2026-10-07","ids":{"openalex":"https://openalex.org/W7220832259","doi":"https://doi.org/10.1016/j.xagr.2026.100706","pmid":"https://pubmed.ncbi.nlm.nih.gov/42997612","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/13742098"},"language":"en","primary_location":{"id":"doi:10.1016/j.xagr.2026.100706","doi":"https://doi.org/10.1016/j.xagr.2026.100706","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.xagr.2026.100706","pdf_url":"https://www.sciencedirect.com/science/article/pii/S2666577826001048/pdf","source":{"id":"https://openalex.org/S4210231035","display_name":"AJOG Global Reports","issn_l":"2666-5778","issn":["2666-5778"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","jufo-1","ki-jl-1","norway-1","poland-20","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"AJOG Global Reports","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://www.sciencedirect.com/science/article/pii/S2666577826001048/pdf","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5049230197","display_name":"Aruna Tantia","orcid":"https://orcid.org/0000-0002-8561-4102","observed_orcids":["https://orcid.org/0000-0002-8561-4102"]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Aruna Tantia","raw_affiliation_strings":["Department of Obstetrics & Gynaecology and Minimal Invasive Gynaecology, ILS Hospitals, Kolkata, West Bengal, India (Tantia and Majumdar)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Obstetrics & Gynaecology and Minimal Invasive Gynaecology, ILS Hospitals, Kolkata, West Bengal, India (Tantia and Majumdar)","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5157877530","display_name":"Shashi Khanna","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Shashi Khanna","raw_affiliation_strings":["Department of Minimal Access Surgery, ILS Hospitals, Kolkata, West Bengal, India (Khanna)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Minimal Access Surgery, ILS Hospitals, Kolkata, West Bengal, India (Khanna)","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5157881943","display_name":"Poonam Kapoor","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Poonam Kapoor","raw_affiliation_strings":["Department of Pathology, ILS Hospitals, Kolkata, West Bengal, India (Kapoor)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pathology, ILS Hospitals, Kolkata, West Bengal, India (Kapoor)","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5057551710","display_name":"Kajari Majumdar","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Kajari Majumdar","raw_affiliation_strings":["Department of Obstetrics & Gynaecology and Minimal Invasive Gynaecology, ILS Hospitals, Kolkata, West Bengal, India (Tantia and Majumdar)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Obstetrics & Gynaecology and Minimal Invasive Gynaecology, ILS Hospitals, Kolkata, West Bengal, India (Tantia and Majumdar)","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":["https://openalex.org/A5049230197"],"corresponding_institution_ids":[],"apc_list":{"value":1980,"currency":"USD","value_usd":1980},"apc_paid":{"value":1980,"currency":"USD","value_usd":1980},"fwci":0.0,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":{"value":0.72571411,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"6","issue":"4","first_page":"100706","last_page":"100706"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10309","display_name":"Acute Myeloid Leukemia Research","score":0.6840999722480774,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10309","display_name":"Acute Myeloid Leukemia Research","score":0.6840999722480774,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10550","display_name":"Ovarian cancer diagnosis and treatment","score":0.19859999418258667,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10989","display_name":"Uterine Myomas and Treatments","score":0.03869999945163727,"subfield":{"id":"https://openalex.org/subfields/2729","display_name":"Obstetrics and Gynecology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/myeloid-sarcoma","display_name":"myeloid sarcoma","score":0.9139999747276306},{"id":"https://openalex.org/keywords/acute-myeloid-leukemia","display_name":"acute myeloid leukemia","score":0.8610000014305115},{"id":"https://openalex.org/keywords/bilateral-ovarian-involvement","display_name":"bilateral ovarian involvement","score":0.7319999933242798},{"id":"https://openalex.org/keywords/fertility-sparing-surgery","display_name":"fertility-sparing surgery","score":0.7229999899864197},{"id":"https://openalex.org/keywords/salpingo-oophorectomy","display_name":"salpingo-oophorectomy","score":0.9639999866485596},{"id":"https://openalex.org/keywords/ovarian-preservation","display_name":"ovarian preservation","score":0.8109999895095825},{"id":"https://openalex.org/keywords/in-vitro-fertilization","display_name":"in vitro fertilization","score":0.8510000109672546},{"id":"https://openalex.org/keywords/myeloperoxidase","display_name":"myeloperoxidase","score":0.7839999794960022},{"id":"https://openalex.org/keywords/c-kit","display_name":"CD117","score":0.7919999957084656},{"id":"https://openalex.org/keywords/cd45","display_name":"CD45","score":0.6800000071525574},{"id":"https://openalex.org/keywords/ovarian-adnexal-masses","display_name":"ovarian adnexal masses","score":0.550000011920929},{"id":"https://openalex.org/keywords/young-women","display_name":"young women","score":0.3700000047683716}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8700000047683716},{"id":"https://openalex.org/C2778613593","wikidata":"https://www.wikidata.org/wiki/Q3680952","display_name":"Myeloid sarcoma","level":3,"score":0.6865000128746033},{"id":"https://openalex.org/C2778729363","wikidata":"https://www.wikidata.org/wiki/Q11688946","display_name":"Myeloid leukemia","level":2,"score":0.5579000115394592},{"id":"https://openalex.org/C2778256501","wikidata":"https://www.wikidata.org/wiki/Q223911","display_name":"Sarcoma","level":2,"score":0.5145000219345093},{"id":"https://openalex.org/C2781100745","wikidata":"https://www.wikidata.org/wiki/Q1977435","display_name":"Debulking","level":4,"score":0.4708999991416931},{"id":"https://openalex.org/C544855455","wikidata":"https://www.wikidata.org/wiki/Q1070952","display_name":"Histopathology","level":2,"score":0.44369998574256897},{"id":"https://openalex.org/C2779282312","wikidata":"https://www.wikidata.org/wiki/Q1956561","display_name":"Myeloid","level":2,"score":0.42489999532699585},{"id":"https://openalex.org/C2778324911","wikidata":"https://www.wikidata.org/wiki/Q9631","display_name":"Ovary","level":2,"score":0.4171999990940094},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.4007999897003174},{"id":"https://openalex.org/C204232928","wikidata":"https://www.wikidata.org/wiki/Q899285","display_name":"Immunohistochemistry","level":2,"score":0.3831999897956848},{"id":"https://openalex.org/C143998085","wikidata":"https://www.wikidata.org/wiki/Q162555","display_name":"Oncology","level":1,"score":0.38019999861717224},{"id":"https://openalex.org/C2779234561","wikidata":"https://www.wikidata.org/wiki/Q11995","display_name":"Pregnancy","level":2,"score":0.38019999861717224},{"id":"https://openalex.org/C2780084626","wikidata":"https://www.wikidata.org/wiki/Q11793790","display_name":"Ovarian tumor","level":4,"score":0.3790000081062317},{"id":"https://openalex.org/C2776694085","wikidata":"https://www.wikidata.org/wiki/Q974135","display_name":"Chemotherapy","level":2,"score":0.36309999227523804},{"id":"https://openalex.org/C29456083","wikidata":"https://www.wikidata.org/wiki/Q1221899","display_name":"Gynecology","level":1,"score":0.3571000099182129},{"id":"https://openalex.org/C2776611710","wikidata":"https://www.wikidata.org/wiki/Q16888295","display_name":"Induction chemotherapy","level":3,"score":0.3555000126361847},{"id":"https://openalex.org/C2779701055","wikidata":"https://www.wikidata.org/wiki/Q929833","display_name":"Rare disease","level":3,"score":0.3361999988555908},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.33160001039505005},{"id":"https://openalex.org/C28328180","wikidata":"https://www.wikidata.org/wiki/Q48196","display_name":"Stem cell","level":2,"score":0.3312000036239624},{"id":"https://openalex.org/C2781230225","wikidata":"https://www.wikidata.org/wiki/Q3150564","display_name":"Ovulation induction","level":4,"score":0.3206000030040741},{"id":"https://openalex.org/C2777408962","wikidata":"https://www.wikidata.org/wiki/Q1128050","display_name":"Hematopoietic stem cell transplantation","level":3,"score":0.3158000111579895},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.31380000710487366},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.30730000138282776},{"id":"https://openalex.org/C109159458","wikidata":"https://www.wikidata.org/wiki/Q919283","display_name":"Haematopoiesis","level":3,"score":0.30469998717308044},{"id":"https://openalex.org/C2776755627","wikidata":"https://www.wikidata.org/wiki/Q408524","display_name":"Cyclophosphamide","level":3,"score":0.3034999966621399},{"id":"https://openalex.org/C2780427987","wikidata":"https://www.wikidata.org/wiki/Q172341","display_name":"Ovarian cancer","level":3,"score":0.29280000925064087},{"id":"https://openalex.org/C90924648","wikidata":"https://www.wikidata.org/wiki/Q120569","display_name":"Gastroenterology","level":1,"score":0.2768999934196472},{"id":"https://openalex.org/C81182388","wikidata":"https://www.wikidata.org/wiki/Q353963","display_name":"Complication","level":2,"score":0.274399995803833},{"id":"https://openalex.org/C2778311097","wikidata":"https://www.wikidata.org/wiki/Q5903784","display_name":"Hormonal therapy","level":4,"score":0.2680000066757202},{"id":"https://openalex.org/C512716672","wikidata":"https://www.wikidata.org/wiki/Q200117","display_name":"In vitro fertilisation","level":3,"score":0.25519999861717224},{"id":"https://openalex.org/C2779013556","wikidata":"https://www.wikidata.org/wiki/Q181876","display_name":"Metastasis","level":3,"score":0.2531999945640564}],"mesh":[],"locations_count":3,"locations":[{"id":"doi:10.1016/j.xagr.2026.100706","doi":"https://doi.org/10.1016/j.xagr.2026.100706","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.xagr.2026.100706","pdf_url":"https://www.sciencedirect.com/science/article/pii/S2666577826001048/pdf","source":{"id":"https://openalex.org/S4210231035","display_name":"AJOG Global Reports","issn_l":"2666-5778","issn":["2666-5778"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","jufo-1","ki-jl-1","norway-1","poland-20","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"AJOG Global Reports","raw_type":"journal-article"},{"id":"pmid:42997612","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/42997612","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"AJOG global reports","raw_type":"Case Reports"},{"id":"pmh:oai:doaj.org/article:a9344cfe644f4d0881752aa96500161d","doi":null,"is_oa":false,"landing_page_url":"https://doaj.org/article/a9344cfe644f4d0881752aa96500161d","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"AJOG Global Reports, Vol 6, Iss 4, Pp 100706- (2026)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.1016/j.xagr.2026.100706","doi":"https://doi.org/10.1016/j.xagr.2026.100706","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.xagr.2026.100706","pdf_url":"https://www.sciencedirect.com/science/article/pii/S2666577826001048/pdf","source":{"id":"https://openalex.org/S4210231035","display_name":"AJOG Global Reports","issn_l":"2666-5778","issn":["2666-5778"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","jufo-1","ki-jl-1","norway-1","poland-20","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"AJOG Global Reports","raw_type":"journal-article"},"sustainable_development_goals":[{"score":1.0,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Case Report","id":"https://openalex.org/study-designs/case-report"}],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W7220832259.pdf","grobid_xml":"https://content.openalex.org/works/W7220832259.grobid-xml"},"referenced_works_count":7,"referenced_works":["https://openalex.org/W1983769365","https://openalex.org/W2014156647","https://openalex.org/W2047737345","https://openalex.org/W2061717209","https://openalex.org/W2125665903","https://openalex.org/W2402831363","https://openalex.org/W2997140210"],"related_works":["https://openalex.org/W4376866111","https://openalex.org/W4389337968","https://openalex.org/W2118249933","https://openalex.org/W2110250284","https://openalex.org/W2804820550","https://openalex.org/W2997140210","https://openalex.org/W2466143209","https://openalex.org/W2997174172","https://openalex.org/W2001047420","https://openalex.org/W3111763520"],"abstract_inverted_index":{"BACKGROUND:":[0],"Myeloid":[1],"sarcoma":[2,93],"is":[3,24],"a":[4,35],"rare":[5],"extramedullary":[6],"manifestation":[7],"of":[8,50,78,147,180,188],"acute":[9],"myeloid":[10,92],"leukemia":[11],"(AML)":[12],"that":[13,192],"may":[14,196],"mimic":[15],"benign":[16],"gynecologic":[17],"disease":[18,29],"and":[19,45,71,85,89,100,105,117,155,170,191,200],"delay":[20],"diagnosis.":[21,65,87],"Ovarian":[22],"involvement":[23],"particularly":[25],"uncommon,":[26],"with":[27,40,62,68,94,115,145],"bilateral":[28,46],"rarely":[30],"reported.":[31],"CASE:":[32],"We":[33],"describe":[34],"24-year-old":[36],"nulliparous":[37],"woman":[38],"presenting":[39],"dysmenorrhea,":[41],"chronic":[42],"pelvic":[43],"pain":[44],"adnexal":[47],"masses":[48],"suggestive":[49],"endometrioma":[51],"on":[52],"ultrasonography.":[53],"Laparoscopy":[54],"demonstrated":[55],"bilaterally":[56],"enlarged":[57],"predominantly":[58],"solid":[59],"ovaries":[60],"inconsistent":[61],"the":[63,79,177,186],"preoperative":[64],"Fertility-conserving":[66],"surgery":[67],"unilateral":[69],"salpingo-oophorectomy":[70],"contralateral":[72],"ovarian":[73,148,184],"conservation":[74],"was":[75,111],"performed":[76],"because":[77],"patient's":[80],"young":[81,205],"age,":[82],"reproductive":[83,201],"goals":[84],"uncertain":[86],"Histopathology":[88],"immunohistochemistry":[90],"confirmed":[91],"variable":[95],"membranous":[96],"positive":[97],"for":[98,103,182],"CD45":[99],"strong":[101],"positivity":[102],"myeloperoxidase,":[104],"CD117.":[106],"Initial":[107],"peripheral":[108],"blood":[109],"smear":[110],"normal;":[112],"however,":[113],"AML":[114],"t(8;21)":[116],"RUNX1-RUNX1T1":[118],"fusion":[119],"developed":[120],"50":[121],"days":[122],"later.":[123],"The":[124],"patient":[125],"subsequently":[126,161],"underwent":[127,162],"cytarabine-based":[128],"chemotherapy":[129],"followed":[130],"by":[131,151],"allogeneic":[132],"hematopoietic":[133],"stem":[134],"cell":[135],"transplantation.":[136],"At":[137],"60-month":[138],"follow-up,":[139],"she":[140],"remains":[141],"in":[142,163,203],"complete":[143],"remission":[144],"restoration":[146],"function,":[149],"evidenced":[150],"regular":[152],"menstrual":[153],"cycles":[154],"normal":[156],"anti-M\u00fcllerian":[157],"hormone":[158],"levels.":[159],"She":[160],"vitro":[164],"fertilization":[165],"using":[166],"her":[167],"own":[168],"eggs":[169],"successfully":[171],"conceived.":[172],"CONCLUSION:":[173],"This":[174],"case":[175],"highlights":[176],"diagnostic":[178],"limitations":[179],"imaging":[181],"atypical":[183],"masses,":[185],"importance":[187],"intraoperative":[189],"reassessment,":[190],"individualized":[193],"fertility-conserving":[194],"management":[195],"achieve":[197],"favorable":[198],"oncologic":[199],"outcomes":[202],"selected":[204],"women.":[206]},"counts_by_year":[],"updated_date":"2026-11-09T13:22:03.289127","created_date":"2026-10-08T00:00:00"}