{"id":"https://openalex.org/W7220768905","doi":null,"title":"Robust foundation model for healthcare","display_name":"Robust foundation model for healthcare","publication_year":2025,"publication_date":"2025-11-18","ids":{"openalex":"https://openalex.org/W7220768905"},"language":"en","primary_location":{"id":"pmh:oai:www.ideals.illinois.edu:2142/132499","doi":null,"is_oa":true,"landing_page_url":"https://hdl.handle.net/2142/132499","pdf_url":"https://www.ideals.illinois.edu/items/139500/bitstreams/450495/data.pdf","source":{"id":"https://openalex.org/S4306401358","display_name":"Illinois Digital Environment for Access to Learning and Scholarship (University of Illinois at Urbana-Champaign)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I2801919071","host_organization_name":"University of Illinois System","host_organization_lineage":["https://openalex.org/I2801919071"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Thesis"},"volume":null,"type":"dissertation","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.ideals.illinois.edu/items/139500/bitstreams/450495/data.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5029029234","display_name":"Zhenbang Wu","orcid":"https://orcid.org/0009-0003-2855-7978","observed_orcids":["https://orcid.org/0009-0003-2855-7978"]},"institutions":[{"id":"https://openalex.org/I157725225","display_name":"University of Illinois Urbana-Champaign","ror":"https://ror.org/047426m28","country_code":"US","type":"education","lineage":["https://openalex.org/I157725225"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Wu, Zhenbang","raw_affiliation_strings":["Graduate College of the University of Illinois Urbana-Champaign , 2025 Urbana , Illinois"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Graduate College of the University of Illinois Urbana-Champaign , 2025 Urbana , Illinois","institution_ids":["https://openalex.org/I157725225"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5029029234"],"corresponding_institution_ids":["https://openalex.org/I157725225"],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T13702","display_name":"Machine Learning in Healthcare","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/1702","display_name":"Artificial Intelligence"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T13702","display_name":"Machine Learning in Healthcare","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/1702","display_name":"Artificial Intelligence"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11636","display_name":"Artificial Intelligence in Healthcare and Education","score":0.0005000000237487257,"subfield":{"id":"https://openalex.org/subfields/2718","display_name":"Health Informatics"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11396","display_name":"Artificial Intelligence in Healthcare","score":0.0003000000142492354,"subfield":{"id":"https://openalex.org/subfields/3605","display_name":"Health Information Management"},"field":{"id":"https://openalex.org/fields/36","display_name":"Health Professions"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/data-fragmentation","display_name":"data fragmentation","score":0.6050000190734863},{"id":"https://openalex.org/keywords/missing-data","display_name":"missing data","score":0.8069999814033508},{"id":"https://openalex.org/keywords/distribution-shift","display_name":"distribution shift","score":0.7900000214576721},{"id":"https://openalex.org/keywords/domain-adaptation","display_name":"domain adaptation","score":0.6790000200271606},{"id":"https://openalex.org/keywords/large-language-models","display_name":"large language models","score":0.6370000243186951},{"id":"https://openalex.org/keywords/instruction-tuning","display_name":"instruction tuning","score":0.718999981880188},{"id":"https://openalex.org/keywords/clinical-data-interpretation","display_name":"clinical data interpretation","score":0.5809999704360962},{"id":"https://openalex.org/keywords/open-source-library","display_name":"open-source library","score":0.7250000238418579}],"concepts":[{"id":"https://openalex.org/C2780966255","wikidata":"https://www.wikidata.org/wiki/Q5474306","display_name":"Foundation (evidence)","level":2,"score":0.5626999735832214},{"id":"https://openalex.org/C160735492","wikidata":"https://www.wikidata.org/wiki/Q31207","display_name":"Health care","level":2,"score":0.48840001225471497},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.4869999885559082},{"id":"https://openalex.org/C127413603","wikidata":"https://www.wikidata.org/wiki/Q11023","display_name":"Engineering","level":0,"score":0.32820001244544983},{"id":"https://openalex.org/C2779343474","wikidata":"https://www.wikidata.org/wiki/Q3109175","display_name":"Context (archaeology)","level":2,"score":0.32710000872612},{"id":"https://openalex.org/C18762648","wikidata":"https://www.wikidata.org/wiki/Q42213","display_name":"Work (physics)","level":2,"score":0.3125},{"id":"https://openalex.org/C42475967","wikidata":"https://www.wikidata.org/wiki/Q194292","display_name":"Operations research","level":1,"score":0.27730000019073486},{"id":"https://openalex.org/C112930515","wikidata":"https://www.wikidata.org/wiki/Q4389547","display_name":"Risk analysis (engineering)","level":1,"score":0.27630001306533813},{"id":"https://openalex.org/C539667460","wikidata":"https://www.wikidata.org/wiki/Q2414942","display_name":"Management science","level":1,"score":0.27390000224113464},{"id":"https://openalex.org/C26517878","wikidata":"https://www.wikidata.org/wiki/Q228039","display_name":"Key (lock)","level":2,"score":0.2702000141143799},{"id":"https://openalex.org/C55587333","wikidata":"https://www.wikidata.org/wiki/Q1133029","display_name":"Engineering ethics","level":1,"score":0.2669000029563904},{"id":"https://openalex.org/C2988170871","wikidata":"https://www.wikidata.org/wiki/Q11000047","display_name":"Healthcare system","level":3,"score":0.2603999972343445}],"mesh":[],"locations_count":1,"locations":[{"id":"pmh:oai:www.ideals.illinois.edu:2142/132499","doi":null,"is_oa":true,"landing_page_url":"https://hdl.handle.net/2142/132499","pdf_url":"https://www.ideals.illinois.edu/items/139500/bitstreams/450495/data.pdf","source":{"id":"https://openalex.org/S4306401358","display_name":"Illinois Digital Environment for Access to Learning and Scholarship (University of Illinois at Urbana-Champaign)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I2801919071","host_organization_name":"University of Illinois System","host_organization_lineage":["https://openalex.org/I2801919071"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Thesis"}],"best_oa_location":{"id":"pmh:oai:www.ideals.illinois.edu:2142/132499","doi":null,"is_oa":true,"landing_page_url":"https://hdl.handle.net/2142/132499","pdf_url":"https://www.ideals.illinois.edu/items/139500/bitstreams/450495/data.pdf","source":{"id":"https://openalex.org/S4306401358","display_name":"Illinois Digital Environment for Access to Learning and Scholarship (University of Illinois at Urbana-Champaign)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I2801919071","host_organization_name":"University of Illinois System","host_organization_lineage":["https://openalex.org/I2801919071"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Thesis"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.7246000170707703}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W7220768905.pdf","grobid_xml":"https://content.openalex.org/works/W7220768905.grobid-xml"},"referenced_works_count":60,"referenced_works":["https://openalex.org/W1991232904","https://openalex.org/W2065240770","https://openalex.org/W2073471108","https://openalex.org/W2130942839","https://openalex.org/W2284851926","https://openalex.org/W2406368917","https://openalex.org/W2518582440","https://openalex.org/W2557074642","https://openalex.org/W2690721124","https://openalex.org/W2742491462","https://openalex.org/W2775078427","https://openalex.org/W2792621217","https://openalex.org/W2805089815","https://openalex.org/W2891113091","https://openalex.org/W2891400669","https://openalex.org/W2896457183","https://openalex.org/W2908510526","https://openalex.org/W2937036051","https://openalex.org/W2964068143","https://openalex.org/W2999645127","https://openalex.org/W3080098168","https://openalex.org/W3080565611","https://openalex.org/W3090721331","https://openalex.org/W3101128828","https://openalex.org/W3105966348","https://openalex.org/W3128252541","https://openalex.org/W3136873846","https://openalex.org/W3154280800","https://openalex.org/W3160137267","https://openalex.org/W3162922479","https://openalex.org/W3176404283","https://openalex.org/W3184497436","https://openalex.org/W4226182655","https://openalex.org/W4252076394","https://openalex.org/W4290927771","https://openalex.org/W4290944617","https://openalex.org/W4308885870","https://openalex.org/W4313439128","https://openalex.org/W4317904523","https://openalex.org/W4318718936","https://openalex.org/W4366330503","https://openalex.org/W4372272739","https://openalex.org/W4384071683","https://openalex.org/W4385562548","https://openalex.org/W4385567484","https://openalex.org/W4387840032","https://openalex.org/W4387929270","https://openalex.org/W4388184543","https://openalex.org/W4392044798","https://openalex.org/W4396914123","https://openalex.org/W4399326970","https://openalex.org/W4402670791","https://openalex.org/W4402671488","https://openalex.org/W4404781813","https://openalex.org/W4406152279","https://openalex.org/W4409283601","https://openalex.org/W4415795495","https://openalex.org/W6926337895","https://openalex.org/W7133197087","https://openalex.org/W7133216094"],"related_works":["https://openalex.org/W7220786289","https://openalex.org/W7211972869","https://openalex.org/W7220812681","https://openalex.org/W7087475951","https://openalex.org/W7220787326","https://openalex.org/W4380355584","https://openalex.org/W7220781462","https://openalex.org/W7220805325","https://openalex.org/W6944698737","https://openalex.org/W7220755006"],"abstract_inverted_index":{"Clinical":[0],"data":[1,47,58,77,85,90,116,151,193,231,256],"are":[2],"routinely":[3],"collected":[4],"during":[5],"patient":[6,50,121,134],"visits,":[7],"encompassing":[8],"demographics,":[9],"diagnoses,":[10],"laboratory":[11],"test":[12],"results,":[13],"medication":[14],"prescriptions,":[15],"medical":[16,255,303],"images,":[17],"and":[18,68,75,82,95,146,176,190,240,257,285,291,315,328],"clinical":[19,31,89,161,192,246,260,293],"notes.While":[20],"there":[21],"is":[22],"growing":[23],"interest":[24],"in":[25,65,80,170,281,302],"applying":[26],"deep":[27,217,278],"learning":[28,218,279],"techniques":[29],"to":[30,42,102,140,152,167,188,269,287],"predictive":[32,162,294],"modeling,":[33],"developing":[34],"robust":[35,290],"models":[36,163,186,295],"for":[37,113,182,216,245,252,276],"healthcare":[38,115,220,237],"remains":[39],"challenging":[40],"due":[41],"several":[43],"key":[44],"obstacles:":[45],"(1)":[46],"fragmentation,":[48],"with":[49,92,143,194],"health":[51,122,128],"records":[52,61,123],"scattered":[53],"across":[54,124],"multiple":[55,107],"institutions;":[56],"(2)":[57],"missingness,":[59],"as":[60],"frequently":[62],"contain":[63],"gaps":[64],"both":[66,324],"features":[67,145],"labels;":[69],"(3)":[70],"distribution":[71],"shift,":[72],"where":[73],"training":[74,139,150],"testing":[76],"often":[78],"differ":[79],"distribution;":[81],"(4)":[83],"complex":[84,195,254],"schema,":[86],"given":[87],"that":[88,164,211],"comes":[91],"varying":[93],"structures":[94],"standardizations.This":[96],"dissertation":[97,305],"presents":[98],"a":[99,179,213,273],"comprehensive":[100,214,274],"approach":[101],"addressing":[103,297],"these":[104,198,263],"challenges":[105,300],"through":[106],"contributions.First,":[108],"I":[109,201],"developed":[110],"foundational":[111,266],"methods":[112,268],"handling":[114,253],"complexities:":[117],"MedLink":[118],"links":[119],"de-identified":[120],"hospitals":[125],"by":[126],"matching":[127],"patterns":[129],"without":[130,311],"relying":[131],"on":[132,219],"sensitive":[133],"identifiers;":[135],"MUSE":[136],"extends":[137],"model":[138,154],"include":[141],"patients":[142],"missing":[144],"labels,":[147],"leveraging":[148],"additional":[149],"improve":[153],"performance;":[155],"SLDG":[156],"supports":[157],"the":[158,203,226,298,312],"development":[159,204],"of":[160,205,235,317],"effectively":[165],"adapt":[166],"domain":[168],"shifts":[169],"target":[171],"data,":[172],"ensuring":[173],"better":[174],"generalizability;":[175],"Llemr":[177],"introduces":[178],"general":[180],"framework":[181,215,275],"instruction-tuning":[183],"large":[184],"language":[185],"(LLMs)":[187],"process":[189],"interpret":[191],"structures.Building":[196],"upon":[197],"methodological":[199],"contributions,":[200,264],"co-led":[202],"PyHealth,":[206],"an":[207],"open-source":[208],"Python":[209],"library":[210,248],"provides":[212,249],"data.PyHealth":[221],"integrates":[222],"lessons":[223],"learned":[224],"from":[225,265],"aforementioned":[227],"research,":[228],"offering":[229],"standardized":[230],"processing":[232],"pipelines,":[233],"implementations":[234],"state-of-the-art":[236],"ML":[238],"models,":[239],"evaluation":[241],"protocols":[242],"specifically":[243],"designed":[244],"applications.The":[247],"practical":[250,270],"tools":[251],"supporting":[258],"various":[259],"prediction":[261],"tasks.Together,":[262],"research":[267],"tools,":[271],"provide":[272],"advancing":[277],"applications":[280],"healthcare,":[282],"enabling":[283],"researchers":[284],"practitioners":[286],"develop":[288],"more":[289],"reliable":[292],"while":[296],"fundamental":[299],"inherent":[301],"data.This":[304],"would":[306],"not":[307],"have":[308,322],"been":[309],"possible":[310],"support,":[313],"guidance,":[314],"encouragement":[316],"many":[318],"remarkable":[319],"individuals":[320],"who":[321],"shaped":[323],"my":[325],"academic":[326],"journey":[327],"personal":[329],"growth.":[330]},"counts_by_year":[],"updated_date":"2026-11-08T12:12:28.789561","created_date":"2026-10-07T00:00:00"}