{"id":"https://openalex.org/W7220728607","doi":"https://doi.org/10.3389/fbioe.2026.1908609","title":"The impact of osteoporosis on spinal biomechanical stability in adolescent idiopathic scoliosis: a narrative review of finite element analysis and bone mineral density assessment","display_name":"The impact of osteoporosis on spinal biomechanical stability in adolescent idiopathic scoliosis: a narrative review of finite element analysis and bone mineral density assessment","publication_year":2026,"publication_date":"2026-10-06","ids":{"openalex":"https://openalex.org/W7220728607","doi":"https://doi.org/10.3389/fbioe.2026.1908609","pmid":"https://pubmed.ncbi.nlm.nih.gov/42903522","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/13680873"},"language":"en","primary_location":{"id":"doi:10.3389/fbioe.2026.1908609","doi":"https://doi.org/10.3389/fbioe.2026.1908609","is_oa":true,"landing_page_url":"https://doi.org/10.3389/fbioe.2026.1908609","pdf_url":"https://www.frontiersin.org/journals/bioengineering-and-biotechnology/articles/10.3389/fbioe.2026.1908609/pdf","source":{"id":"https://openalex.org/S2595131146","display_name":"Frontiers in Bioengineering and Biotechnology","issn_l":"2296-4185","issn":["2296-4185"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","jufo-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320527","host_organization_name":"Frontiers Media","host_organization_lineage":["https://openalex.org/P4310320527"],"host_organization_lineage_names":["Frontiers Media"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in Bioengineering and Biotechnology","raw_type":"journal-article"},"volume":null,"type":"review","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://www.frontiersin.org/journals/bioengineering-and-biotechnology/articles/10.3389/fbioe.2026.1908609/pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5083938718","display_name":"Zhaomeng Hou","orcid":"https://orcid.org/0000-0001-7151-3610","observed_orcids":["https://orcid.org/0000-0001-7151-3610"]},"institutions":[{"id":"https://openalex.org/I131434179","display_name":"Nanjing University of Chinese Medicine","ror":"https://ror.org/04523zj19","country_code":"CN","type":"education","lineage":["https://openalex.org/I131434179"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Zhaomeng Hou","raw_affiliation_strings":["Department of Orthopedics and Traumatology, Yancheng TCM Hospital","Department of Orthopedics and Traumatology, Yancheng TCM Hospital Affiliated to Nanjing University of Chinese Medicine"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Orthopedics and Traumatology, Yancheng TCM Hospital","institution_ids":[]},{"raw_affiliation_string":"Department of Orthopedics and Traumatology, Yancheng TCM Hospital Affiliated to Nanjing University of Chinese Medicine","institution_ids":["https://openalex.org/I131434179"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5157779034","display_name":"Jiaojiao Wu","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I83519826","display_name":"Nanjing Medical University","ror":"https://ror.org/059gcgy73","country_code":"CN","type":"education","lineage":["https://openalex.org/I83519826"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Jiaojiao Wu","raw_affiliation_strings":["Department of Pharmacology, School of Basic Medical Science, Nanjing Medical University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pharmacology, School of Basic Medical Science, Nanjing Medical University","institution_ids":["https://openalex.org/I83519826"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5084827918","display_name":"Hua L\u00fc","orcid":"https://orcid.org/0000-0003-2559-3597","observed_orcids":["https://orcid.org/0000-0003-2559-3597","https://orcid.org/0009-0004-6301-9945"]},"institutions":[{"id":"https://openalex.org/I131434179","display_name":"Nanjing University of Chinese Medicine","ror":"https://ror.org/04523zj19","country_code":"CN","type":"education","lineage":["https://openalex.org/I131434179"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Hua Lu","raw_affiliation_strings":["Department of Orthopedics and Traumatology, Yancheng TCM Hospital","Department of Orthopedics and Traumatology, Yancheng TCM Hospital Affiliated to Nanjing University of Chinese Medicine"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Orthopedics and Traumatology, Yancheng TCM Hospital","institution_ids":[]},{"raw_affiliation_string":"Department of Orthopedics and Traumatology, Yancheng TCM Hospital Affiliated to Nanjing University of Chinese Medicine","institution_ids":["https://openalex.org/I131434179"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5148274894","display_name":"Chaoqun Chen","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I131434179","display_name":"Nanjing University of Chinese Medicine","ror":"https://ror.org/04523zj19","country_code":"CN","type":"education","lineage":["https://openalex.org/I131434179"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Chaoqun Chen","raw_affiliation_strings":["Department of Orthopedics and Traumatology, Yancheng TCM Hospital","Department of Orthopedics and Traumatology, Yancheng TCM Hospital Affiliated to Nanjing University of Chinese Medicine"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Orthopedics and Traumatology, Yancheng TCM Hospital","institution_ids":[]},{"raw_affiliation_string":"Department of Orthopedics and Traumatology, Yancheng TCM Hospital Affiliated to Nanjing University of Chinese Medicine","institution_ids":["https://openalex.org/I131434179"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5071059449","display_name":"Tingliang Han","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I131434179","display_name":"Nanjing University of Chinese Medicine","ror":"https://ror.org/04523zj19","country_code":"CN","type":"education","lineage":["https://openalex.org/I131434179"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Tingliang Han","raw_affiliation_strings":["Department of Orthopedics and Traumatology, Yancheng TCM Hospital","Department of Orthopedics and Traumatology, Yancheng TCM Hospital Affiliated to Nanjing University of Chinese Medicine"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Orthopedics and Traumatology, Yancheng TCM Hospital","institution_ids":[]},{"raw_affiliation_string":"Department of Orthopedics and Traumatology, Yancheng TCM Hospital Affiliated to Nanjing University of Chinese Medicine","institution_ids":["https://openalex.org/I131434179"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5071059449","https://openalex.org/A5083938718"],"corresponding_institution_ids":["https://openalex.org/I131434179"],"apc_list":{"value":3150,"currency":"CHF","value_usd":3801},"apc_paid":{"value":3150,"currency":"CHF","value_usd":3801},"fwci":0.0,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":{"value":0.62341492,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"14","issue":null,"first_page":"1908609","last_page":"1908609"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11030","display_name":"Scoliosis diagnosis and treatment","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11030","display_name":"Scoliosis diagnosis and treatment","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12830","display_name":"Pectus Deformity Diagnosis and Treatment","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10071","display_name":"Bone health and osteoporosis research","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2732","display_name":"Orthopedics and Sports Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/adolescent-idiopathic-scoliosis","display_name":"adolescent idiopathic scoliosis","score":0.9769999980926514},{"id":"https://openalex.org/keywords/osteoporosis","display_name":"osteoporosis","score":0.9980000257492065},{"id":"https://openalex.org/keywords/bone-mineral-density","display_name":"bone mineral density","score":0.9819999933242798},{"id":"https://openalex.org/keywords/curve-progression","display_name":"curve progression","score":0.7960000038146973},{"id":"https://openalex.org/keywords/spinal-flexibility","display_name":"spinal flexibility","score":0.9890000224113464}],"concepts":[{"id":"https://openalex.org/C2776541429","wikidata":"https://www.wikidata.org/wiki/Q165328","display_name":"Osteoporosis","level":2,"score":0.7472000122070312},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.7448999881744385},{"id":"https://openalex.org/C3020000205","wikidata":"https://www.wikidata.org/wiki/Q2412849","display_name":"Narrative review","level":2,"score":0.7027999758720398},{"id":"https://openalex.org/C2992931878","wikidata":"https://www.wikidata.org/wiki/Q7577457","display_name":"Spinal deformity","level":3,"score":0.6807000041007996},{"id":"https://openalex.org/C2993634128","wikidata":"https://www.wikidata.org/wiki/Q174857","display_name":"Idiopathic scoliosis","level":3,"score":0.5911999940872192},{"id":"https://openalex.org/C2776886416","wikidata":"https://www.wikidata.org/wiki/Q4941567","display_name":"Bone mineral","level":3,"score":0.511900007724762},{"id":"https://openalex.org/C1862650","wikidata":"https://www.wikidata.org/wiki/Q186005","display_name":"Physical therapy","level":1,"score":0.46459999680519104},{"id":"https://openalex.org/C170700871","wikidata":"https://www.wikidata.org/wiki/Q193378","display_name":"Biomechanics","level":2,"score":0.44350001215934753},{"id":"https://openalex.org/C2779982284","wikidata":"https://www.wikidata.org/wiki/Q1182746","display_name":"Deformity","level":2,"score":0.43720000982284546},{"id":"https://openalex.org/C2779329777","wikidata":"https://www.wikidata.org/wiki/Q2304401","display_name":"Bone density","level":3,"score":0.42250001430511475},{"id":"https://openalex.org/C99508421","wikidata":"https://www.wikidata.org/wiki/Q2678675","display_name":"Physical medicine and rehabilitation","level":1,"score":0.4203999936580658},{"id":"https://openalex.org/C207886595","wikidata":"https://www.wikidata.org/wiki/Q1456138","display_name":"Pathological","level":2,"score":0.4056999981403351},{"id":"https://openalex.org/C2780955175","wikidata":"https://www.wikidata.org/wiki/Q174857","display_name":"Scoliosis","level":2,"score":0.40369999408721924},{"id":"https://openalex.org/C137627325","wikidata":"https://www.wikidata.org/wiki/Q156318","display_name":"Etiology","level":2,"score":0.35429999232292175},{"id":"https://openalex.org/C29694066","wikidata":"https://www.wikidata.org/wiki/Q118301","display_name":"Orthodontics","level":1,"score":0.32100000977516174},{"id":"https://openalex.org/C140608501","wikidata":"https://www.wikidata.org/wiki/Q7318358","display_name":"Review article","level":2,"score":0.314300000667572},{"id":"https://openalex.org/C60644358","wikidata":"https://www.wikidata.org/wiki/Q128570","display_name":"Bioinformatics","level":1,"score":0.30079999566078186},{"id":"https://openalex.org/C2777814797","wikidata":"https://www.wikidata.org/wiki/Q7577460","display_name":"Spinal fracture","level":2,"score":0.29919999837875366},{"id":"https://openalex.org/C146249460","wikidata":"https://www.wikidata.org/wiki/Q2914991","display_name":"Fixation (population genetics)","level":3,"score":0.29089999198913574},{"id":"https://openalex.org/C2911152345","wikidata":"https://www.wikidata.org/wiki/Q482853","display_name":"Spinal Curvatures","level":3,"score":0.2897000014781952},{"id":"https://openalex.org/C2777425516","wikidata":"https://www.wikidata.org/wiki/Q17083560","display_name":"Quantitative computed tomography","level":4,"score":0.2750000059604645},{"id":"https://openalex.org/C2779974597","wikidata":"https://www.wikidata.org/wiki/Q28448986","display_name":"Clinical Practice","level":2,"score":0.2727999985218048},{"id":"https://openalex.org/C2779473830","wikidata":"https://www.wikidata.org/wiki/Q1540899","display_name":"MEDLINE","level":2,"score":0.26669999957084656},{"id":"https://openalex.org/C107130276","wikidata":"https://www.wikidata.org/wiki/Q133805","display_name":"Epidemiology","level":2,"score":0.2533999979496002},{"id":"https://openalex.org/C2780811821","wikidata":"https://www.wikidata.org/wiki/Q1641175","display_name":"Rachis","level":2,"score":0.2529999911785126}],"mesh":[],"locations_count":4,"locations":[{"id":"doi:10.3389/fbioe.2026.1908609","doi":"https://doi.org/10.3389/fbioe.2026.1908609","is_oa":true,"landing_page_url":"https://doi.org/10.3389/fbioe.2026.1908609","pdf_url":"https://www.frontiersin.org/journals/bioengineering-and-biotechnology/articles/10.3389/fbioe.2026.1908609/pdf","source":{"id":"https://openalex.org/S2595131146","display_name":"Frontiers in Bioengineering and Biotechnology","issn_l":"2296-4185","issn":["2296-4185"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","jufo-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320527","host_organization_name":"Frontiers Media","host_organization_lineage":["https://openalex.org/P4310320527"],"host_organization_lineage_names":["Frontiers Media"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in Bioengineering and Biotechnology","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:13680873","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC13680873/","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC13680873/pdf/fbioe-14-1908609.pdf","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Front Bioeng Biotechnol","raw_type":"Text"},{"id":"pmid:42903522","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/42903522","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in bioengineering and biotechnology","raw_type":"Journal Article"},{"id":"pmh:oai:doaj.org/article:4eda3204e9644ef084177973be14db8a","doi":null,"is_oa":false,"landing_page_url":"https://doaj.org/article/4eda3204e9644ef084177973be14db8a","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Frontiers in Bioengineering and Biotechnology, Vol 14 (2026)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.3389/fbioe.2026.1908609","doi":"https://doi.org/10.3389/fbioe.2026.1908609","is_oa":true,"landing_page_url":"https://doi.org/10.3389/fbioe.2026.1908609","pdf_url":"https://www.frontiersin.org/journals/bioengineering-and-biotechnology/articles/10.3389/fbioe.2026.1908609/pdf","source":{"id":"https://openalex.org/S2595131146","display_name":"Frontiers in Bioengineering and Biotechnology","issn_l":"2296-4185","issn":["2296-4185"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","jufo-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320527","host_organization_name":"Frontiers Media","host_organization_lineage":["https://openalex.org/P4310320527"],"host_organization_lineage_names":["Frontiers Media"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in Bioengineering and Biotechnology","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.9763000011444092,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G7326384372","display_name":null,"funder_award_id":"82505790","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"}],"funders":[{"id":"https://openalex.org/F4320321001","display_name":"National Natural Science Foundation of China","ror":"https://ror.org/01h0zpd94"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W7220728607.pdf","grobid_xml":"https://content.openalex.org/works/W7220728607.grobid-xml"},"referenced_works_count":136,"referenced_works":["https://openalex.org/W1972878603","https://openalex.org/W1973269777","https://openalex.org/W2026477779","https://openalex.org/W2035340650","https://openalex.org/W2069541444","https://openalex.org/W2169626622","https://openalex.org/W2997675573","https://openalex.org/W3004210915","https://openalex.org/W3006850207","https://openalex.org/W3019986263","https://openalex.org/W3025525399","https://openalex.org/W3032953812","https://openalex.org/W3036660915","https://openalex.org/W3042361885","https://openalex.org/W3044527740","https://openalex.org/W3047396934","https://openalex.org/W3049752919","https://openalex.org/W3084958424","https://openalex.org/W3088912108","https://openalex.org/W3092261696","https://openalex.org/W3092382087","https://openalex.org/W3112388137","https://openalex.org/W3126437909","https://openalex.org/W3127179633","https://openalex.org/W3127236711","https://openalex.org/W3131038419","https://openalex.org/W3135034627","https://openalex.org/W3158303346","https://openalex.org/W3158905580","https://openalex.org/W3165174953","https://openalex.org/W3174854796","https://openalex.org/W3175668259","https://openalex.org/W3187006177","https://openalex.org/W3189068962","https://openalex.org/W3190887015","https://openalex.org/W3199221583","https://openalex.org/W3199755597","https://openalex.org/W3207501037","https://openalex.org/W3207642615","https://openalex.org/W4213264597","https://openalex.org/W4220689124","https://openalex.org/W4220736330","https://openalex.org/W4224323544","https://openalex.org/W4225485333","https://openalex.org/W4280598680","https://openalex.org/W4283824256","https://openalex.org/W4292013891","https://openalex.org/W4292560266","https://openalex.org/W4296991025","https://openalex.org/W4296992034","https://openalex.org/W4298088561","https://openalex.org/W4302284085","https://openalex.org/W4308712437","https://openalex.org/W4310526461","https://openalex.org/W4313362067","https://openalex.org/W4318263677","https://openalex.org/W4321091639","https://openalex.org/W4323357058","https://openalex.org/W4327614337","https://openalex.org/W4361010977","https://openalex.org/W4366548255","https://openalex.org/W4366606473","https://openalex.org/W4367834249","https://openalex.org/W4376254365","https://openalex.org/W4376872639","https://openalex.org/W4380077897","https://openalex.org/W4385751194","https://openalex.org/W4386293291","https://openalex.org/W4386725487","https://openalex.org/W4386894211","https://openalex.org/W4387397632","https://openalex.org/W4387865326","https://openalex.org/W4388571920","https://openalex.org/W4388767685","https://openalex.org/W4389438759","https://openalex.org/W4391097957","https://openalex.org/W4391657325","https://openalex.org/W4391885780","https://openalex.org/W4392245816","https://openalex.org/W4392894173","https://openalex.org/W4392956311","https://openalex.org/W4396534520","https://openalex.org/W4399230087","https://openalex.org/W4399326624","https://openalex.org/W4400205547","https://openalex.org/W4400618406","https://openalex.org/W4400907465","https://openalex.org/W4401043753","https://openalex.org/W4401364874","https://openalex.org/W4401471922","https://openalex.org/W4401720836","https://openalex.org/W4401851613","https://openalex.org/W4402337435","https://openalex.org/W4403733907","https://openalex.org/W4404286322","https://openalex.org/W4404304953","https://openalex.org/W4405769063","https://openalex.org/W4406001297","https://openalex.org/W4406998904","https://openalex.org/W4407405317","https://openalex.org/W4407640861","https://openalex.org/W4408939804","https://openalex.org/W4409341444","https://openalex.org/W4409974986","https://openalex.org/W4410185945","https://openalex.org/W4410776009","https://openalex.org/W4411283141","https://openalex.org/W4411901807","https://openalex.org/W4412014703","https://openalex.org/W4412020002","https://openalex.org/W4412053735","https://openalex.org/W4412199521","https://openalex.org/W4412940028","https://openalex.org/W4413100430","https://openalex.org/W4413745127","https://openalex.org/W4413760158","https://openalex.org/W4413907496","https://openalex.org/W4415002106","https://openalex.org/W4415112952","https://openalex.org/W4415216035","https://openalex.org/W4415237302","https://openalex.org/W4415243957","https://openalex.org/W4415734700","https://openalex.org/W4415895991","https://openalex.org/W4415990976","https://openalex.org/W4416607812","https://openalex.org/W4416841252","https://openalex.org/W4417045185","https://openalex.org/W4417162118","https://openalex.org/W4417201930","https://openalex.org/W7124499741","https://openalex.org/W7128496106","https://openalex.org/W7134891743","https://openalex.org/W7139132173","https://openalex.org/W7141464082","https://openalex.org/W7146967950"],"related_works":["https://openalex.org/W4225485333","https://openalex.org/W2101512156","https://openalex.org/W4389438759","https://openalex.org/W2788227268","https://openalex.org/W3029362030","https://openalex.org/W772189296","https://openalex.org/W2069541444","https://openalex.org/W4385751194","https://openalex.org/W4292013891","https://openalex.org/W2006343718"],"abstract_inverted_index":{"Adolescent":[0],"Idiopathic":[1],"Scoliosis":[2],"(AIS)":[3],"is":[4],"a":[5,64,143,147],"complex":[6],"three-dimensional":[7],"spinal":[8,45,123],"deformity":[9],"whose":[10],"precise":[11],"etiology":[12],"and":[13,39,44,56,130,142,153,158,162],"pathological":[14],"mechanisms":[15,105,118],"remain":[16],"incompletely":[17],"understood.":[18],"In":[19],"recent":[20],"years,":[21],"increasing":[22],"attention":[23],"has":[24],"focused":[25],"on":[26,67,102],"the":[27,30,53,77,96,103,110,114,125,131],"association":[28],"between":[29],"prevalent":[31],"phenomenon":[32],"of":[33,59,95,113,127,133,150],"reduced":[34],"bone":[35],"mineral":[36],"density":[37],"(BMD)":[38],"osteoporosis":[40,60,108],"in":[41,61],"AIS":[42,115,151],"patients":[43],"biomechanical":[46,111],"stability.":[47],"This":[48,137],"review":[49,138],"aims":[50],"to":[51,72],"summarize":[52],"epidemiological":[54],"characteristics":[55],"assessment":[57,85,157],"methods":[58],"AIS,":[62],"with":[63,87],"primary":[65],"focus":[66],"elucidating":[68],"how":[69],"it":[70],"contributes":[71],"curve":[73,128],"progression":[74],"by":[75,106],"influencing":[76],"spine's":[78],"mechanical":[79],"properties.":[80],"By":[81],"integrating":[82],"clinical":[83,156],"BMD":[84],"data":[86],"analyses":[88],"from":[89],"patient-specific,":[90],"image-based":[91],"finite":[92],"element":[93],"models":[94],"spine,":[97],"this":[98],"article":[99],"systematically":[100],"elaborates":[101],"specific":[104],"which":[107],"affects":[109],"stability":[112],"spine.":[116],"These":[117],"encompass":[119],"vertebral":[120],"body":[121],"strength,":[122],"flexibility,":[124],"risk":[126],"progression,":[129],"outcomes":[132],"internal":[134],"fixation":[135],"surgery.":[136],"provides":[139],"novel":[140],"perspectives":[141],"theoretical":[144],"foundation":[145],"for":[146,154],"deeper":[148],"understanding":[149],"pathophysiology":[152],"optimizing":[155],"developing":[159],"individualized":[160],"prevention":[161],"treatment":[163],"strategies.":[164]},"counts_by_year":[],"updated_date":"2026-10-29T09:56:32.521200","created_date":"2026-10-07T00:00:00"}